CNTA Centessa Pharmaceuticals plc - American Depositary Shares
$39.72
Price · May 20, 2026
Fundamentals as of May 5, 2026
52W Range
$11–$40
98% of range
Analyst Rating
HOLD
19 analysts
Price Target
$45
+12% upside
P/E (TTM)
-17.1
ROE
-45.3%
Net Profit Margin
-1316.9%
CNTA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$39.72
Market Cap
$3.73B
P/E (TTM)
-17.1
EPS (TTM)
$-1.46
Revenue (TTM)
$15M
Div Yield
—
ROE
-45.3%
Debt/Equity
0.2
52W Range
$11 – $40
CNTA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$15M
2022-12-31
→
2025-12-31
EPS
$-1.46
2021-12-31
→
2025-12-31
Free Cash Flow
$-194M
2022-12-31
→
2025-12-31
Margins
-1316.9%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
CNTA
Peer Median
P/E (TTM)
-17.1
87.0
P/S (TTM)
248.8
10.2
P/B
7.1
1.7
EV / EBITDA
-17.2
—
Price / FCF
-19.2
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
CNTA
Peer Median
Operating Margin
-1384.6%
—
Net Profit Margin
-1316.9%
-439.7%
ROA
-31.2%
-29.2%
ROE
-45.3%
-35.5%
ROIC
-32.9%
—
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
CNTA
Peer Median
Debt / Equity
0.2
0.0
Current Ratio
8.6
6.2
Quick Ratio
6.9
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
CNTA
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
CNTA
Peer Median
CNTA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
19 analysts
- Strong Buy 4 21.1%
- Buy 5 26.3%
- Hold 10 52.6%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
7 analysts · 2026-05-17
Median
$42.00
Mean
$44.57
Now
$39.72
Low
$38.00
High
$62.00
Median target
$42.00
+5.8%
Mean target
$44.57
+12.2%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.03%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.52 | $-0.40 | -0.12% |
| Dec. 31, 2025 | $-0.48 | $-0.39 | -0.09% |
| Sept. 30, 2025 | $-0.41 | $-0.40 | -0.01% |
| June 30, 2025 | $-0.38 | $-0.35 | -0.03% |
| March 31, 2025 | $-0.20 | $-0.38 | 0.18% |
| Dec. 31, 2024 | $-0.58 | $-0.46 | -0.12% |
Peer Comparison Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| CNTA | $3.73B | -17.1 | — | -1316.9% | -45.3% | — |
| ROIV | $7.02B | -42.0 | -11.2% | -592.0% | -3.2% | — |
| KNSA | $3.15B | 55.0 | 60.1% | 8.7% | 11.1% | — |
| IMCR | $1.76B | -48.9 | 28.9% | -8.9% | -9.2% | — |
| CMPS | $663M | -2.2 | — | — | -524.8% | — |
| AUTL | — | -1.8 | 644.9% | -381.4% | -109.6% | — |
| BCYC | $491M | -2.2 | 105.8% | -301.7% | -34.2% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $15M | $0 | $7M | $0 | |
| SG&A Expense | $50M | $51M | $54M | $55M | |
| Operating Income | $-208M | $-201M | $-171M | $-212M | |
| Interest Expense | · | · | $10M | $7M | |
| Interest Income | $21M | $14M | $10M | · | |
| Other Non-op | $3M | $-2M | $-5M | $2M | |
| Pretax Income | $-196M | $-233M | $-176M | $-217M | |
| Income Tax | $2M | $3M | $-25M | $-747.0K | |
| Net Income | $-198M | $-236M | $-151M | $-216M | |
| EPS (Basic) | $-1.46 | $-2.06 | $-1.57 | $-2.31 | |
| EPS (Diluted) | $-1.46 | $-2.06 | $-1.57 | $-2.31 | |
| Shares (Basic) | 135,715,608 | 114,473,449 | 96,177,578 | 93,400,513 | |
| Shares (Diluted) | 135,715,608 | 114,473,449 | 96,177,578 | 93,400,513 | |
| EBITDA | $-207M | $-200M | $-170M | $-212M |
Balance Sheet 25
| Metric | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $61M | $383M | $128M | $394M | |
| Short-term Investments | $233M | $99M | $129M | $0 | |
| Prepaid Expense | $19M | $10M | $21M | $20M | |
| Other Current Assets | $2M | $1M | $2M | $3M | |
| Current Assets | $368M | $536M | $315M | $438M | |
| PP&E (Net) | $807.0K | $744.0K | $1M | $1M | |
| PP&E (Gross) | $2M | $2M | $2M | $1M | |
| Accum. Depreciation | $1M | $791.0K | $462.0K | $164.0K | |
| Other Non-current Assets | $1M | $2M | $3M | $2M | |
| Total Assets | $687M | $577M | $360M | $444M | |
| Accounts Payable | $8M | $7M | $12M | $14M | |
| Accrued Liabilities | $35M | $51M | $28M | $25M | |
| Current Liabilities | $43M | $58M | $39M | $38M | |
| Capital Leases | $8M | $8M | $9M | $0 | |
| Other Non-current Liabilities | $29.0K | $29.0K | $29.0K | $0 | |
| Total Liabilities | $161M | $175M | $124M | $108M | |
| Long-term Debt | $110M | $109M | $0 | · | |
| Total Debt | $110M | $109M | $76M | $70M | |
| Common Stock | $405.0K | $359.0K | $273.0K | $265.0K | |
| Paid-in Capital | $1.71B | $1.39B | $987M | $939M | |
| Retained Earnings | $-1.19B | $-989M | $-753M | $-602M | |
| AOCI | $3M | $4M | $1M | $-1M | |
| Stockholders' Equity | $527M | $402M | $236M | $336M | |
| Liabilities + Equity | $687M | $577M | $360M | $444M | |
| Shares Outstanding | 149,228,068 | 132,631,587 | 98,774,827 | 94,843,391 |
Cash Flow 13
| Metric | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| D&A | $921.0K | $942.0K | $810.0K | $131.0K | |
| Stock-based Comp | $31M | $34M | $29M | $25M | |
| Deferred Tax | $3M | $3M | $-27M | $-3M | |
| Other Non-cash | $-31M | $57M | $-13M | $-7M | |
| Operating Cash Flow | $-194M | $-142M | $-160M | $-201M | |
| CapEx | $371.0K | $34.0K | $169.0K | $1M | |
| Investing Cash Flow | $-419M | $31M | $-127M | $-931.0K | |
| Stock Issued | · | · | $21M | $0 | |
| Net Stock Activity | · | · | $21M | · | |
| Financing Cash Flow | $292M | $365M | $21M | $457.0K | |
| Net Change in Cash | $-321M | $255M | $-266M | $-201M | |
| Free Cash Flow | $-194M | $-142M | $-161M | $-202M | |
| Levered FCF | · | · | $-169M | · |
Profitability 7
| Metric | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | -1384.6% | · | -2499.4% | · | |
| Net Margin | -1316.9% | · | -2204.7% | · | |
| Pretax Margin | -1304.8% | · | -2570.3% | · | |
| EBITDA Margin | -1378.5% | · | -2487.6% | · | |
| ROA | -31.2% | -50.3% | -37.6% | -40.3% | |
| ROE | -45.3% | -52.3% | -61.0% | -61.0% | |
| ROIC | -32.9% | -39.9% | -47.1% | -52.1% |
Liquidity & Solvency 5
| Metric | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 8.6 | 9.2 | 8.0 | 11.4 | |
| Quick Ratio | 6.9 | 8.3 | 6.5 | 10.3 | |
| Debt / Equity | 0.2 | 0.3 | 0.3 | 0.2 | |
| LT Debt / Equity | 0.2 | 0.3 | 0.3 | 0.2 | |
| Interest Coverage | · | · | -17.3 | · |
Efficiency 1
| Metric | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | · |
Valuation (TTM) 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $15M | $0 | $7M | $0 | |
| Net Income TTM | $-198M | $-236M | $-151M | $-216M | |
| Market Cap | $3.73B | $2.22B | $786M | $294M | |
| Enterprise Value | $3.55B | $1.85B | $605M | $-30M | |
| P/E | -17.1 | -8.1 | -5.1 | -1.3 | |
| P/S | 248.8 | · | 114.7 | · | |
| P/B | 7.1 | 5.5 | 3.3 | 0.9 | |
| P / Tangible Book | 7.1 | 5.5 | 3.3 | 0.9 | |
| P / Cash Flow | -19.3 | -15.6 | -4.9 | -1.5 | |
| P / FCF | -19.2 | -15.6 | -4.9 | -1.5 | |
| EV / EBITDA | -17.2 | -9.2 | -3.6 | 0.1 | |
| EV / FCF | -18.3 | -13.0 | -3.8 | 0.1 | |
| EV / Revenue | 236.5 | · | 88.3 | · | |
| Earnings Yield | -5.8% | -12.3% | -19.7% | -74.5% |
Income Statement 14
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $15M | $0 | $0 | $0 | $0 | |
| SG&A Expense | $20M | $14M | $12M | $12M | $12M | $14M | $13M | $11M | $13M | |
| Operating Income | $-80M | $-68M | $-54M | $-55M | $-31M | $-75M | $-46M | $-44M | $-36M | |
| Interest Expense | · | · | · | · | · | · | · | · | $3M | |
| Interest Income | $5M | $4M | $4M | $4M | $8M | $5M | $3M | $3M | $3M | |
| Other Non-op | $-1M | $103.0K | $-2M | $4M | $1M | $-4M | $4M | $154.0K | $-2M | |
| Pretax Income | $-78M | $-67M | $-55M | $-50M | $-25M | $-110M | $-42M | $-43M | $-38M | |
| Income Tax | $850.0K | $-522.0K | $166.0K | $778.0K | $1M | $1M | $608.0K | $705.0K | $481.0K | |
| Net Income | $-79M | $-66M | $-55M | $-50M | $-26M | $-111M | $-43M | $-44M | $-38M | |
| EPS (Basic) | $-0.52 | $-0.47 | $-0.41 | $-0.38 | $-0.20 | $-0.91 | $-0.37 | $-0.40 | $-0.38 | |
| EPS (Diluted) | $-0.52 | $-0.47 | $-0.41 | $-0.38 | $-0.20 | $-0.91 | $-0.37 | $-0.40 | $-0.38 | |
| Shares (Basic) | 153,549,733 | -265,158,830 | 134,163,492 | 133,677,405 | 133,033,541 | -211,157,357 | 116,253,902 | 109,489,184 | 99,887,720 | |
| Shares (Diluted) | 153,549,733 | -265,158,830 | 134,163,492 | 133,677,405 | 133,033,541 | -211,157,357 | 116,253,902 | 109,489,184 | 99,887,720 | |
| EBITDA | $-80M | · | $-54M | $-55M | $-31M | · | · | · | $-36M |
Balance Sheet 25
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $62M | $61M | $51M | $44M | $105M | $383M | $395M | $127M | $118M | |
| Short-term Investments | $214M | $233M | $195M | $206M | $179M | $99M | $123M | $167M | $112M | |
| Prepaid Expense | $16M | $19M | $12M | $9M | $14M | $10M | $16M | $19M | $18M | |
| Other Current Assets | $2M | $2M | $3M | $2M | $2M | $1M | $3M | $2M | $2M | |
| Current Assets | $349M | $368M | $308M | $300M | $348M | $536M | $568M | $356M | $284M | |
| PP&E (Net) | $722.0K | $807.0K | $894.0K | $733.0K | $681.0K | $744.0K | $821.0K | $903.0K | $952.0K | |
| PP&E (Gross) | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | $1M | $1M | $1M | $928.0K | $854.0K | $791.0K | $714.0K | $632.0K | $549.0K | |
| Other Non-current Assets | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Total Assets | $642M | $687M | $448M | $492M | $528M | $577M | $610M | $399M | $328M | |
| Accounts Payable | $11M | $8M | $9M | $6M | $5M | $7M | $7M | $5M | $7M | |
| Accrued Liabilities | $26M | $35M | $20M | $24M | $19M | $51M | $19M | $21M | $20M | |
| Current Liabilities | $37M | $43M | $29M | $30M | $24M | $58M | $26M | $27M | $27M | |
| Capital Leases | $7M | $8M | $8M | $8M | $8M | $8M | $8M | $9M | $9M | |
| Other Non-current Liabilities | $29.0K | $29.0K | $29.0K | $29.0K | $29.0K | $29.0K | $29.0K | $29.0K | $29.0K | |
| Total Liabilities | $154M | $161M | $147M | $147M | $142M | $175M | $111M | $112M | $113M | |
| Long-term Debt | $110M | $110M | $110M | $110M | $109M | $109M | · | · | · | |
| Total Debt | $110M | · | $110M | $110M | $109M | · | · | · | $77M | |
| Common Stock | $419.0K | $405.0K | $364.0K | $363.0K | $362.0K | $359.0K | $357.0K | $309.0K | $277.0K | |
| Paid-in Capital | $1.75B | $1.71B | $1.42B | $1.41B | $1.40B | $1.39B | $1.37B | $1.12B | $1.00B | |
| Retained Earnings | $-1.27B | $-1.19B | $-1.12B | $-1.07B | $-1.01B | $-989M | $-877M | $-835M | $-791M | |
| AOCI | $1M | $3M | $3M | $2M | $2M | $4M | $2M | $2M | $2M | |
| Stockholders' Equity | $487M | $527M | $302M | $345M | $386M | $402M | $499M | $287M | $215M | |
| Liabilities + Equity | $642M | $687M | $448M | $492M | $528M | $577M | $610M | $399M | $328M | |
| Shares Outstanding | 154,728,966 | 149,228,068 | 134,421,149 | 133,913,556 | 133,554,598 | 132,631,587 | 131,659,103 | 113,177,764 | 100,481,993 |
Cash Flow 13
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $239.0K | $241.0K | $237.0K | $226.0K | $217.0K | $230.0K | $236.0K | $236.0K | $240.0K | |
| Stock-based Comp | $11M | $8M | $7M | $8M | $8M | $8M | $8M | $9M | $8M | |
| Deferred Tax | $828.0K | $233.0K | $255.0K | $1M | $995.0K | $398.0K | $1M | $567.0K | $434.0K | |
| Other Non-cash | $-5M | · | · | · | $-40M | · | · | · | $-8M | |
| Operating Cash Flow | $-72M | $-56M | $-58M | $-22M | $-57M | $-43M | $-21M | $-41M | $-37M | |
| CapEx | · | $11.0K | $234.0K | · | · | $0 | $34.0K | $0 | $0 | |
| Investing Cash Flow | $43M | $-218M | $62M | $-40M | $-222M | $25M | $45M | $-55M | $17M | |
| Stock Issued | $0 | · | · | · | $6M | · | · | · | $10M | |
| Net Stock Activity | $0 | · | · | · | · | · | · | · | $10M | |
| Financing Cash Flow | $30M | $283M | $3M | $2M | $3M | $3M | $246M | $105M | $10M | |
| Net Change in Cash | $1M | $11M | $7M | $-61M | $-278M | $-12M | $268M | $9M | $-10M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | $-37M | |
| Levered FCF | · | · | · | · | · | · | · | · | $-40M |
Profitability 7
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | -205.2% | · | · | · | · | |
| Net Margin | · | · | · | · | -174.2% | · | · | · | · | |
| Pretax Margin | · | · | · | · | -164.9% | · | · | · | · | |
| EBITDA Margin | · | · | · | · | -203.7% | · | · | · | · | |
| ROA | -13.6% | · | -10.4% | -11.3% | -6.1% | · | · | · | -10.4% | |
| ROE | -18.1% | · | -13.7% | -15.9% | -8.7% | · | · | · | -15.0% | |
| ROIC | -13.5% | · | -13.1% | -12.2% | -6.6% | · | · | · | -12.5% |
Liquidity & Solvency 5
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.5 | · | 10.6 | 10.1 | 14.4 | · | · | · | 10.4 | |
| Quick Ratio | 7.6 | · | 8.5 | 8.4 | 11.8 | · | · | · | 8.4 | |
| Debt / Equity | 0.2 | · | 0.4 | 0.3 | 0.3 | · | · | · | 0.4 | |
| LT Debt / Equity | 0.2 | · | 0.4 | 0.3 | 0.3 | · | · | · | 0.4 | |
| Interest Coverage | · | · | · | · | · | · | · | · | -14.3 |
Efficiency 1
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | · | · |
Valuation (TTM) 14
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $15M | · | $15M | $15M | $15M | · | · | · | · | |
| Net Income TTM | $-211M | · | $-174M | $-163M | $-151M | · | $-163M | $-145M | $-152M | |
| Market Cap | $6.15B | · | $3.26B | $1.76B | $1.92B | · | · | · | $1.14B | |
| Enterprise Value | $5.98B | · | $3.12B | $1.62B | $1.75B | · | · | · | $982M | |
| P/E | -26.3 | · | -17.8 | -9.7 | -10.7 | · | -10.3 | -6.3 | -7.2 | |
| P/S | 409.7 | · | 217.3 | 117.3 | 128.0 | · | · | · | · | |
| P/B | 12.6 | · | 10.8 | 5.1 | 5.0 | · | · | · | 5.3 | |
| P / Tangible Book | 12.6 | · | 10.8 | 5.1 | 5.0 | · | 4.2 | 3.6 | 5.3 | |
| P / Cash Flow | -85.1 | · | · | · | -33.5 | · | · | · | -30.5 | |
| P / FCF | · | · | · | · | · | · | · | · | -30.5 | |
| EV / EBITDA | -75.2 | · | -58.1 | -29.6 | -57.1 | · | · | · | -27.4 | |
| EV / FCF | · | · | · | · | · | · | · | · | -26.3 | |
| EV / Revenue | 398.6 | · | 208.2 | 107.9 | 116.4 | · | · | · | · | |
| Earnings Yield | -3.8% | · | -5.6% | -10.3% | -9.4% | · | -9.7% | -16.0% | -13.9% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $15M | $0 | $7M | $0 | — |
| Operating Margin % | -1384.6% | — | -2499.4% | — | — |
| Net Income | $-198M | $-236M | $-151M | $-216M | $-381M |
| Diluted EPS | $-1.46 | $-2.06 | $-1.57 | $-2.31 | $-5.07 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Debt / Equity | 0.2 | 0.3 | 0.3 | 0.2 | — |
| Current Ratio | 8.6 | 9.2 | 8.0 | 11.4 | — |
| Quick Ratio | 6.9 | 8.3 | 6.5 | 10.3 | — |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-194M | $-142M | $-161M | $-202M | — |
Latest News Recent headlines mentioning this company
My Metrics Your personal watchlist — selected rows from Full Fundamentals
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