Insider at

04

Insider transactions

05
0 buys (P) 10 sells (S) Net: $-16,705,490 + 73 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

73 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
July 7, 2026 IONS S 10b5-1 15,000 $85.46 $1,281,900 0 Indirect -100.00% Disposed -49.1% (price as of 2026-10-02)
July 7, 2026 IONS S 10b5-1 5,536 $83.58 $462,699 75,018 Direct -6.87% Disposed -47.9% (price as of 2026-10-02)
March 3, 2026 IONS S 10b5-1 802 $80.76 $64,770 80,554 Direct -0.99% Disposed -46.1% (price as of 2026-10-02)
March 3, 2026 IONS S 10b5-1 12,687 $79.88 $1,013,438 81,356 Direct -13.49% Disposed -45.5% (price as of 2026-10-02)
March 3, 2026 IONS S 10b5-1 71,600 $79.10 $5,663,560 94,043 Direct -43.23% Disposed -45.0% (price as of 2026-10-02)
Feb. 2, 2026 IONS S 16,463 $83.03 $1,366,923 80,293 Direct -17.01% Disposed -47.6% (price as of 2026-10-02)
Feb. 2, 2026 IONS S 48,626 $83.03 $4,037,417 80,293 Direct -37.72% Disposed -47.6% (price as of 2026-10-02)
Feb. 2, 2026 IONS S 20,000 $82.60 $1,652,000 80,293 Direct -19.94% Disposed -47.3% (price as of 2026-10-02)
Jan. 30, 2026 IONS S 5,885 $82.95 $488,161 100,293 Direct -5.54% Disposed -47.5% (price as of 2026-10-02)
Jan. 16, 2026 IONS S 8,977 $75.15 $674,622 94,757 Direct -8.65% Disposed -42.1% (price as of 2026-10-02)
Sept. 5, 2025 IONS S 10b5-1 6,000 $59.60 $357,600 82,679 Direct -6.77% Disposed -26.9% (price as of 2026-10-02)
Sept. 3, 2025 IONS S 10b5-1 33,909 $60.62 $2,055,564 101,570 Direct -25.03% Disposed -28.2% (price as of 2026-10-02)
Sept. 2, 2025 IONS S 10b5-1 5,000 $49.14 $245,700 88,679 Direct -5.34% Disposed -11.4% (price as of 2026-10-02)
Aug. 18, 2025 IONS S 10b5-1 10,000 $43.98 $439,800 93,466 Direct -9.67% Disposed -1.0% (price as of 2026-10-02)
Jan. 31, 2025 IONS S 1,327 $32.46 $43,074 93,146 Direct -1.40% Disposed 34.1% (price as of 2026-10-02)
Jan. 16, 2025 IONS S 6,752 $32.90 $222,141 90,866 Direct -6.92% Disposed 32.3% (price as of 2026-10-02)
Feb. 2, 2024 IONS S 1,885 $49.52 $93,345 79,047 Direct -2.33% Disposed -12.1% (price as of 2026-10-02)
Feb. 2, 2024 IONS S 1,853 $49.52 $91,761 79,079 Direct -2.29% Disposed -12.1% (price as of 2026-10-02)
Jan. 17, 2024 IONS S 6,745 $50.42 $340,083 77,323 Direct -8.02% Disposed -13.6% (price as of 2026-10-02)
Dec. 21, 2023 IONS S 16,113 $49.29 $794,210 65,754 Direct -19.68% Disposed -11.7% (price as of 2026-10-02)
Dec. 20, 2023 IONS S 6,500 $49.64 $322,660 65,754 Direct -9.00% Disposed -12.3% (price as of 2026-10-02)
Dec. 14, 2023 IONS S 8,610 $50.19 $432,136 65,754 Direct -11.58% Disposed -13.2% (price as of 2026-10-02)
Dec. 14, 2023 IONS S 14,002 $49.21 $689,038 65,754 Direct -17.56% Disposed -11.5% (price as of 2026-10-02)
Sept. 28, 2023 IONS S 10b5-1 4,460 $46.50 $207,390 65,754 Direct -6.35% Disposed -6.4% (price as of 2026-10-02)
Feb. 6, 2023 IONS S 1,813 $40.57 $73,553 69,651 Direct -2.54% Disposed 7.3% (price as of 2026-10-02)
Jan. 18, 2023 IONS S 6,978 $38.89 $271,374 67,855 Direct -9.32% Disposed 12.0% (price as of 2026-10-02)
Dec. 4, 2020 IONS S 10b5-1 7,947 $51.04 $405,615 32,476 Direct -19.66% Disposed -14.7% (price as of 2026-10-02)

Showing latest 100 of 416 transactions

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
July 7, 2026 IONS Restricted Stock Unit Common Stock (15,000) $0.00 · 15,000 Disposed
March 3, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (16,463) $32.60 Jan. 2, 2032 16,463 Disposed
March 3, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (48,626) $60.89 Jan. 1, 2027 48,626 Disposed
Feb. 2, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (48,626) $60.89 Jan. 1, 2027 48,626 Disposed
Feb. 2, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (16,463) $32.60 Jan. 2, 2032 16,463 Disposed
Jan. 15, 2026 IONS Restricted Stock Unit [F8] Common Stock (9,675) · · 9,675 Acquired
Jan. 15, 2026 IONS Restricted Stock Unit Common Stock (21,055) · · 21,055 Disposed
Jan. 15, 2026 IONS Performance Restricted Stock Units [F4] Common Stock (25,800) $0.00 · 25,800 Acquired
Jan. 2, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (19,350) $79.67 Jan. 1, 2036 19,350 Acquired
Sept. 3, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (46,800) $53.77 Jan. 1, 2026 46,800 Disposed
Aug. 18, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (10,000) $32.60 Jan. 2, 2032 10,000 Disposed
Jan. 15, 2025 IONS Restricted Stock Unit Common Stock (18,011) · · 18,011 Disposed
Jan. 15, 2025 IONS Restricted Stock Unit [F6] Common Stock (33,000) · · 33,000 Acquired
Jan. 15, 2025 IONS Performance Restricted Stock Units [F4] Common Stock (22,000) $0.00 · 22,000 Acquired
Jan. 2, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (22,000) $34.69 Jan. 1, 2035 22,000 Acquired
Jan. 16, 2024 IONS Restricted Stock Unit Common Stock (18,314) · · 18,314 Disposed
Jan. 15, 2024 IONS Restricted Stock Unit [F3] Common Stock (20,400) · · 20,400 Acquired
Jan. 15, 2024 IONS Performance Restricted Stock Units [F1] Common Stock (17,000) $0.00 · 17,000 Acquired
Jan. 2, 2024 IONS Non-Qualified Stock Option (right to buy) Common Stock (27,200) $52.87 Jan. 1, 2034 27,200 Acquired
Dec. 21, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (16,113) $47.34 Jan. 2, 2024 16,113 Disposed
Dec. 20, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (6,500) $47.34 Jan. 2, 2024 6,500 Disposed
Dec. 14, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (8,610) $47.34 Jan. 2, 2024 8,610 Disposed
Dec. 14, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (14,002) $47.34 Jan. 2, 2024 14,002 Disposed
Jan. 17, 2023 IONS Restricted Stock Unit Common Stock (19,417) · · 19,417 Disposed
Jan. 15, 2023 IONS Restricted Stock Unit [F3] Common Stock (16,387) · · 16,387 Acquired
Jan. 15, 2023 IONS Performance Restricted Stock Units [F1] Common Stock (13,656) $0.00 · 13,656 Acquired
Jan. 3, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (21,849) $37.58 Jan. 2, 2033 21,849 Acquired
Jan. 18, 2022 IONS Restricted Stock Unit Common Stock (18,842) · · 18,842 Disposed
Jan. 15, 2022 IONS Restricted Stock Unit [F3] Common Stock (14,435) · · 14,435 Acquired
Jan. 15, 2022 IONS Performance Restricted Stock Units [F1] Common Stock (10,826) $0.00 · 10,826 Acquired
Jan. 3, 2022 IONS Non-Qualified Stock Option (right to buy) Common Stock (28,869) $32.60 Jan. 2, 2032 28,869 Acquired
Jan. 15, 2021 IONS Restricted Stock Units Common Stock (15,520) · · 15,520 Disposed
Jan. 15, 2021 IONS Restricted Stock Units Common Stock (20,822) · · 20,822 Acquired
Jan. 4, 2021 IONS Employee Stock Option (right to buy) Common Stock (46,850) $56.78 Jan. 3, 2028 46,850 Acquired
Dec. 4, 2020 IONS Employee Stock Option (right to buy) Common Stock (0) $39.87 Jan. 1, 2021 7,947 Disposed
Dec. 2, 2020 IONS Employee Stock Option (right to buy) Common Stock (0) $39.87 Jan. 1, 2021 7,053 Disposed
Nov. 3, 2020 IONS Employee Stock Option (right to buy) Common Stock (15,000) $39.87 Jan. 1, 2021 15,000 Disposed
June 25, 2020 IONS Employee Stock Option (right to buy) Common Stock (15,000) $39.87 Jan. 1, 2021 15,000 Disposed
Jan. 15, 2020 IONS Restricted Stock Units Common Stock (11,711) · · 11,711 Disposed
Jan. 15, 2020 IONS Restricted Stock Units Common Stock (21,612) · · 21,612 Acquired
Jan. 2, 2020 IONS Employee Stock Option (right to buy) Common Stock (48,626) $60.89 Jan. 1, 2027 48,626 Acquired
Feb. 1, 2019 IONS Employee Stock Option (right to buy) Common Stock (9,013) $14.69 Jan. 29, 2020 9,013 Acquired
Jan. 15, 2019 IONS Restricted Stock Units Common Stock (7,822) · · 7,822 Disposed
Jan. 15, 2019 IONS Restricted Stock Units Common Stock (20,797) · · 20,797 Acquired
Jan. 2, 2019 IONS Employee Stock Option (right to buy) Common Stock (46,800) $53.77 Jan. 1, 2026 46,800 Acquired
Nov. 1, 2018 IONS Employee Stock Option (right to buy) Common Stock (12,500) $14.69 Jan. 29, 2020 12,500 Acquired
Aug. 8, 2018 IONS Employee Stock Option (right to buy) Common Stock (12,487) $14.69 Jan. 29, 2020 12,487 Acquired
Aug. 8, 2018 IONS Employee Stock Option (right to buy) Common Stock (13) $7.25 Jan. 2, 2019 13 Acquired
May 11, 2018 IONS Employee Stock Option (right to buy) Common Stock (12,500) $7.25 Jan. 2, 2019 12,500 Acquired
Feb. 1, 2018 IONS Employee Stock Option (right to buy) Common Stock (12,500) $7.25 Jan. 2, 2019 12,500 Acquired
Jan. 15, 2018 IONS Restricted Stock Units Common Stock (6,663) · · 6,663 Disposed
Jan. 15, 2018 IONS Restricted Stock Units Common Stock (12,137) · · 12,137 Acquired
Jan. 2, 2018 IONS Employee Stock Option (right to buy) Common Stock (54,619) $49.25 Jan. 1, 2025 54,619 Acquired
Oct. 18, 2017 IONS Employee Stock Option (right to buy) Common Stock (12,250) $10.29 Jan. 2, 2018 12,250 Disposed
July 24, 2017 IONS Employee Stock Option (right to buy) Common Stock (10,000) $10.29 Jan. 2, 2018 10,000 Disposed
March 3, 2017 IONS Employee Stock Option (right to buy) Common Stock (5,000) $10.29 Jan. 2, 2018 5,000 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (1,594) · · 1,594 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (1,311) · · 1,311 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (1,875) · · 1,875 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (1,415) · · 1,415 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (7,537) · · 7,537 Acquired
Jan. 3, 2017 IONS Employee Stock Option (right to buy) Common Stock (45,225) $47.34 Jan. 2, 2024 45,225 Acquired
Nov. 9, 2016 IONS Employee Stock Option (right to buy) Common Stock (22,805) $11.27 Jan. 3, 2017 22,805 Disposed
Nov. 7, 2016 IONS Employee Stock Option (right to buy) Common Stock (5,000) $11.27 Jan. 3, 2017 5,000 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (1,311) · · 1,311 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (1,875) · · 1,875 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (1,415) · · 1,415 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (694) · · 694 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (6,373) · · 6,373 Acquired
Jan. 4, 2016 IONS Employee Stock Option (right to buy) Common Stock (38,240) $61.68 Jan. 3, 2023 38,240 Acquired
Dec. 16, 2015 IONS Employee Stock Option (right to buy) Common Stock (3,909) $14.47 Jan. 1, 2016 3,909 Disposed
Dec. 15, 2015 IONS Employee Stock Option (right to buy) Common Stock (4,000) $14.47 Jan. 1, 2016 4,000 Disposed
Nov. 10, 2015 IONS Employee Stock Option (right to buy) Common Stock (5,000) $14.47 Jan. 1, 2016 5,000 Disposed
Nov. 6, 2015 IONS Employee Stock Option (right to buy) Common Stock (5,000) $14.47 Jan. 1, 2016 5,000 Disposed
March 24, 2015 IONS Employee Stock Option (right to buy) Common Stock (9,000) $14.47 Jan. 2, 2016 9,000 Disposed
March 23, 2015 IONS Employee Stock Option (right to buy) Common Stock (6,000) $14.47 Jan. 1, 2016 6,000 Disposed
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (5,242) · · 5,242 Acquired
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (694) · · 694 Disposed
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (1,415) · · 1,415 Disposed
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (1,875) · · 1,875 Disposed
Jan. 2, 2015 IONS Employee Stock Option (right to buy) Common Stock (31,457) $61.57 Jan. 1, 2022 31,457 Acquired
Aug. 27, 2014 IONS Employee Stock Option (right to buy) Common Stock (5,000) $15.38 Jan. 1, 2015 5,000 Disposed
June 23, 2014 IONS Employee Stock Option (right to buy) Common Stock (11,200) $15.38 Jan. 1, 2015 11,200 Disposed
Jan. 15, 2014 IONS Restricted Stock Units Common Stock (695) · · 695 Disposed
Jan. 15, 2014 IONS Restricted Stock Units Common Stock (1,415) · · 1,415 Disposed
Jan. 15, 2014 IONS Restricted Stock Units Common Stock (7,500) · · 7,500 Acquired
Jan. 2, 2014 IONS Employee Stock Option (right to buy) Common Stock (45,000) $39.87 Jan. 1, 2021 45,000 Acquired
Dec. 5, 2013 IONS Employee Stock Option (right to buy) Common Stock (10,000) $15.38 Jan. 1, 2015 10,000 Disposed
Sept. 19, 2013 IONS Employee Stock Option (right to buy) Common Stock (10,000) $15.38 Jan. 1, 2015 10,000 Disposed
Sept. 9, 2013 IONS Employee Stock Option (right to buy) Common Stock (10,000) $15.38 Jan. 1, 2015 10,000 Disposed
May 1, 2013 IONS Employee Stock Option (right to buy) Common Stock (6,145) $11.12 Jan. 1, 2014 6,145 Disposed
May 1, 2013 IONS Employee Stock Option (right to buy) Common Stock (23,800) $6.81 Jan. 1, 2014 23,800 Disposed
April 30, 2013 IONS Employee Stock Option (right to buy) Common Stock (30,000) $11.12 Jan. 1, 2014 30,000 Disposed
Jan. 30, 2013 IONS Restricted Stock Units Common Stock (5,660) · · 5,660 Acquired
Jan. 30, 2013 IONS Employee Stock Option (right to buy) Common Stock (34,000) $14.69 Jan. 29, 2020 34,000 Acquired
Jan. 15, 2013 IONS Restricted Stock Units Common Stock · · 695 Disposed
July 9, 2012 IONS Employee Stock Option (right to buy) Common Stock (5,000) $6.81 Jan. 1, 2014 5,000 Disposed
July 9, 2012 IONS Employee Stock Option (right to buy) Common Stock (5,500) $6.84 Jan. 1, 2013 5,500 Disposed
July 3, 2012 IONS Employee Stock Option (right to buy) Common Stock' (6,000) $6.84 Jan. 1, 2013 6,000 Disposed
Jan. 3, 2012 IONS Employee Stock Option (right to buy) Common Stock (25,013) $7.25 Jan. 2, 2022 25,013 Acquired

Showing latest 100 of 137 transactions

Exercise/conversion price is blank when not applicable (e.g. RSUs).