Insider at

04

Insider transactions

05
0 buys (P) 6 sells (S) Net: $-3,556,351 + 37 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

37 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
April 16, 2026 IONS S 973 $75.04 $73,014 67,500 Direct -1.42% Disposed -42.0% (price as of 2026-10-05)
Jan. 30, 2026 IONS S 6,179 $83.03 $513,042 66,247 Direct -8.53% Disposed -47.6% (price as of 2026-10-05)
Jan. 16, 2026 IONS S 8,480 $75.11 $636,933 60,435 Direct -12.31% Disposed -42.1% (price as of 2026-10-05)
Nov. 6, 2025 IONS S 10b5-1 8,000 $76.17 $609,360 48,826 Direct -14.08% Disposed -42.9% (price as of 2026-10-05)
Oct. 15, 2025 IONS S 10b5-1 12,425 $72.23 $897,458 56,826 Direct -17.94% Disposed -39.8% (price as of 2026-10-05)
Oct. 14, 2025 IONS S 10b5-1 11,475 $72.03 $826,544 56,826 Direct -16.80% Disposed -39.6% (price as of 2026-10-05)
April 16, 2025 IONS S 680 $28.37 $19,292 56,660 Direct -1.19% Disposed 53.3% (price as of 2026-10-05)
Jan. 16, 2025 IONS S 5,400 $32.70 $176,580 55,051 Direct -8.93% Disposed 33.0% (price as of 2026-10-05)
April 16, 2024 IONS S 905 $41.66 $37,702 46,156 Direct -1.92% Disposed 4.4% (price as of 2026-10-05)
Jan. 17, 2024 IONS S 4,497 $50.42 $226,739 44,582 Direct -9.16% Disposed -13.7% (price as of 2026-10-05)
April 18, 2023 IONS S 672 $36.50 $24,528 36,528 Direct -1.81% Disposed 19.2% (price as of 2026-10-05)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
April 15, 2026 IONS Restricted Stock Unit Common Stock (1,875) · · 1,875 Disposed
Jan. 15, 2026 IONS Restricted Stock Unit [F8] Common Stock (9,675) · · 9,675 Acquired
Jan. 15, 2026 IONS Restricted Stock Unit Common Stock (20,089) · · 20,089 Disposed
Jan. 15, 2026 IONS Performance Restricted Stock Units [F4] Common Stock (25,800) $0.00 · 25,800 Acquired
Jan. 2, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (19,350) $79.67 Jan. 1, 2036 19,350 Acquired
Oct. 15, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (12,425) $53.77 Jan. 1, 2026 12,425 Disposed
Oct. 14, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (11,475) $53.77 Jan. 1, 2026 11,475 Disposed
April 15, 2025 IONS Restricted Stock Unit Common Stock (1,875) · · 1,875 Disposed
Jan. 15, 2025 IONS Restricted Stock Unit Common Stock (14,283) · · 14,283 Disposed
Jan. 15, 2025 IONS Restricted Stock Unit [F5] Common Stock (33,000) · · 33,000 Acquired
Jan. 15, 2025 IONS Performance Restricted Stock Units [F3] Common Stock (22,000) $0.00 · 22,000 Acquired
Jan. 2, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (22,000) $34.69 Jan. 1, 2035 22,000 Acquired
April 15, 2024 IONS Restricted Stock Unit Common Stock (1,875) · · 1,875 Disposed
Jan. 16, 2024 IONS Restricted Stock Unit Common Stock (12,080) · · 12,080 Disposed
Jan. 15, 2024 IONS Restricted Stock Unit [F3] Common Stock (20,400) · · 20,400 Acquired
Jan. 15, 2024 IONS Performance Restricted Stock Units [F1] Common Stock (17,000) $0.00 · 17,000 Acquired
Jan. 2, 2024 IONS Non-Qualified Stock Option (right to buy) Common Stock (27,200) $52.87 Jan. 1, 2034 27,200 Acquired
Dec. 28, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (11,500) $47.34 Jan. 2, 2024 11,500 Disposed
April 17, 2023 IONS Restricted Stock Unit Common Stock (1,875) · · 1,875 Disposed

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 16 holdings

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Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
March 24, 2023 IONS Common Stock 35,325 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (19,500) 19,500 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (15,000) 15,000 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (22,942) 22,942 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (26,982) 26,982 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (31,500) 31,500 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (23,900) 23,900 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (22,000) 22,000 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (26,063) 26,063 Direct
March 24, 2023 IONS Non-Qualified Stock Option (right to buy)→ Common Stock (15,500) 15,500 Direct
March 24, 2023 IONS Performance Restricted Stock Units [F10]→ Common Stock (14,338) 14,338 Direct
March 24, 2023 IONS Restricted Stock Unit [F12]→ Common Stock (2,896) 2,896 Direct
March 24, 2023 IONS Restricted Stock Unit [F12]→ Common Stock (4,888) 4,888 Direct
March 24, 2023 IONS Restricted Stock Unit [F12]→ Common Stock (7,312) 7,312 Direct
March 24, 2023 IONS Restricted Stock Unit [F12]→ Common Stock (7,500) 7,500 Direct
March 24, 2023 IONS Restricted Stock Unit [F12]→ Common Stock (17,207) 17,207 Direct

Compensation (DEF 14A)

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Matched by name from proxy statements (DEF 14A) — verify against the filing.

Fiscal yearSalaryBonusStock awards Option awardsNon-equity incentivePension changeOtherTotal
2025 $580,154 $617,284 $1,095,930 $366,767 · · $48,009 $3,245,054

Figures from the Summary Compensation Table of the company's proxy statement (DEF 14A). Compensation is not a recommendation.