Insider at

04

Insider transactions

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0 buys (P) 0 sells (S) Net: $0 + 8 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

No open-market trades on record; showing all filings.

DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
July 15, 2019 IONS M 3,542 · · 3,798 Direct +1383.59% Acquired (price as of 2026-10-02)
July 15, 2019 IONS F 1,225 $67.86 $83,128 2,573 Direct -32.25% Disposed -35.8% (price as of 2026-10-02)
July 15, 2019 IONS M 3,542 · · 10,625 Direct -25.00% Disposed (price as of 2026-10-02)
July 1, 2019 IONS J 256 $45.70 $11,699 256 Direct · Acquired -4.7% (price as of 2026-10-02)
Jan. 15, 2019 IONS A 13,065 · · 13,065 Direct · Acquired (price as of 2026-10-02)
Jan. 2, 2019 IONS A 29,400 · · 29,400 Direct · Acquired (price as of 2026-10-02)
July 15, 2018 IONS A 14,167 · · 14,167 Direct · Acquired (price as of 2026-10-02)
June 18, 2018 IONS A 63,750 · · 63,750 Direct · Acquired (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

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DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
July 15, 2019 IONS Restricted Stock Units Common Stock (3,542) · · 3,542 Disposed
Jan. 15, 2019 IONS Restricted Stock Units Common Stock (13,065) · · 13,065 Acquired
Jan. 2, 2019 IONS Employee Stock Option (right to buy) Common Stock (29,400) $53.77 Jan. 1, 2026 29,400 Acquired
July 15, 2018 IONS Restricted Stock Units Common Stock (14,167) · · 14,167 Acquired
June 18, 2018 IONS Employee Stock Option (right to buy) Common Stock (63,750) $43.60 June 17, 2025 63,750 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 1 holding

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Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
June 18, 2018 IONS No Securities Owned 0 Direct