Insider at

04

Insider transactions

05
2 buys (P) 26 sells (S) Net: $-7,196,725 + 3 non-open-market transactions below Avg return of open purchases vs close of 2026-10-23: 5.7% 12 months to the week close of 2026-10-23

Price change vs the latest weekly close (updated to the current quote in your browser when available), split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

3 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Oct. 14, 2026 PVLA S 10b5-1 476 $121.14 $57,663 139,314 Direct -0.34% Disposed 3.3% (price as of )
Oct. 14, 2026 PVLA S 10b5-1 2,072 $122.62 $254,069 137,242 Direct -1.49% Disposed 2.0% (price as of )
Oct. 14, 2026 PVLA S 10b5-1 2,604 $123.29 $321,047 134,638 Direct -1.90% Disposed 1.5% (price as of )
Oct. 14, 2026 PVLA S 10b5-1 920 $124.37 $114,420 133,718 Direct -0.68% Disposed 0.6% (price as of )
Oct. 14, 2026 PVLA S 10b5-1 597 $125.33 $74,822 133,121 Direct -0.45% Disposed -0.2% (price as of )
Oct. 14, 2026 PVLA S 10b5-1 505 $126.55 $63,908 132,616 Direct -0.38% Disposed -1.1% (price as of )
Oct. 13, 2026 PVLA S 10b5-1 2,004 $128.52 $257,554 144,960 Direct -1.36% Disposed -2.7% (price as of )
Oct. 13, 2026 PVLA S 10b5-1 1,644 $129.23 $212,454 143,316 Direct -1.13% Disposed -3.2% (price as of )
Oct. 13, 2026 PVLA S 10b5-1 990 $130.48 $129,175 142,326 Direct -0.69% Disposed -4.1% (price as of )
Oct. 13, 2026 PVLA S 10b5-1 1,035 $131.49 $136,092 141,291 Direct -0.73% Disposed -4.9% (price as of )
Oct. 13, 2026 PVLA S 10b5-1 579 $132.40 $76,660 140,712 Direct -0.41% Disposed -5.5% (price as of )
Oct. 13, 2026 PVLA S 10b5-1 922 $133.72 $123,290 139,790 Direct -0.66% Disposed -6.4% (price as of )
Oct. 12, 2026 PVLA S 10b5-1 5,095 $132.62 $675,699 155,021 Direct -3.18% Disposed -5.7% (price as of )
Oct. 12, 2026 PVLA S 10b5-1 2,458 $133.25 $327,528 152,563 Direct -1.59% Disposed -6.1% (price as of )
Oct. 12, 2026 PVLA S 10b5-1 3,335 $134.21 $447,590 149,228 Direct -2.19% Disposed -6.8% (price as of )
Oct. 12, 2026 PVLA S 10b5-1 1,447 $135.50 $196,068 147,781 Direct -0.97% Disposed -7.7% (price as of )
Oct. 12, 2026 PVLA S 10b5-1 817 $136.44 $111,471 146,964 Direct -0.55% Disposed -8.3% (price as of )
Sept. 15, 2026 PVLA S 954 $149.38 $142,509 160,939 Direct -0.59% Disposed -16.3% (price as of )
Sept. 15, 2026 PVLA S 263 $150.40 $39,555 160,676 Direct -0.16% Disposed -16.8% (price as of )
Sept. 15, 2026 PVLA S 560 $151.33 $84,745 160,116 Direct -0.35% Disposed -17.3% (price as of )
Sept. 14, 2026 PVLA S 5,632 $151.46 $853,023 169,613 Direct -3.21% Disposed -17.4% (price as of )
Sept. 14, 2026 PVLA S 6,160 $152.12 $937,059 163,453 Direct -3.63% Disposed -17.8% (price as of )
Sept. 14, 2026 PVLA S 1,560 $153.10 $238,836 161,893 Direct -0.95% Disposed -18.3% (price as of )
Sept. 11, 2026 PVLA S 6,520 $150.62 $982,042 181,096 Direct -3.48% Disposed -16.9% (price as of )
Sept. 11, 2026 PVLA S 4,577 $151.72 $694,422 176,519 Direct -2.53% Disposed -17.5% (price as of )
Sept. 11, 2026 PVLA S 1,274 $153.06 $194,998 175,245 Direct -0.72% Disposed -18.3% (price as of )
March 30, 2026 PVLA P 445 $112.30 $49,974 187,616 Direct +0.24% Acquired 11.4% (price as of )
Feb. 27, 2026 PVLA P 4,000 $125.00 $500,000 187,171 Direct +2.18% Acquired 0.1% (price as of )
April 9, 2025 PVLA P 2,500 $20.13 $50,325 183,171 Direct +1.38% Acquired 521.5% (price as of )
April 9, 2025 PVLA P 2,490 $20.27 $50,472 13,516 Indirect +22.58% Acquired 517.2% (price as of )
Dec. 18, 2024 PVLA P 4,000 $12.93 $51,720 180,671 Direct +2.26% Acquired 867.5% (price as of )

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
June 10, 2026 PVLA Stock Option (Right to Buy) Common Stock (3,000) $102.19 June 10, 2036 3,000 Acquired
June 10, 2025 PVLA Non-Qualified Stock Option (right to buy) Common Stock (12,350) $26.23 June 10, 2035 12,350 Acquired
Dec. 13, 2024 PVLA Stock Option (right to buy) Common Stock (24,700) $13.60 Dec. 13, 2034 24,700 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 4 holdings

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Dec. 16, 2024 PVLA Common Stock 176,671 Direct
Dec. 16, 2024 PVLA Common Stock 11,026 Indirect
Dec. 16, 2024 PVLA Stock Option (right to buy)→ Common Stock (6,963) 6,963 Direct
Dec. 16, 2024 PVLA Stock Option (right to buy)→ Common Stock (11,462) 11,462 Direct

Holdings reported on Form 4 5 reported holdings

08

Positions listed on each Form 4 without a transaction in that filing (Table I and II holdings), newest filing first.

DateTickerSecuritySharesExercise priceExpirationOwnership
Oct. 14, 2026 PVLA Common Stock 13,516 · · Indirect
Sept. 15, 2026 PVLA Common Stock 13,516 · · Indirect
April 1, 2026 PVLA Common Stock 13,516 · · Indirect
March 2, 2026 PVLA Common Stock 13,516 · · Indirect
Dec. 19, 2024 PVLA Common Stock 11,026 · · Indirect