HOUGEN ELIZABETH L

CIK 1074773 · View on SEC EDGAR ↗

Insider

First SEC filing: March 18, 2026 · Latest: March 18, 2026

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Insider at

Insider transactions

0 buys (P) 6 sells (S) Net: $-21,117,075 + 80 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

80 other filings hidden
Date Ticker Code Shares Price Value Owned after Δ own A/D vs now
March 17, 2026 IONS S 10b5-1 10,172 $73.21 $744,692 82,660 Direct -10.96% Disposed -18.2% (price as of 2026-08-21)
March 16, 2026 IONS S 10b5-1 205,608 $72.38 $14,881,907 102,272 Direct -66.78% Disposed -17.3% (price as of 2026-08-21)
March 16, 2026 IONS S 10b5-1 9,440 $72.76 $686,854 92,832 Direct -9.23% Disposed -17.7% (price as of 2026-08-21)
Jan. 30, 2026 IONS S 6,988 $83.24 $581,681 132,881 Direct -5.00% Disposed -28.1% (price as of 2026-08-21)
Jan. 16, 2026 IONS S 12,922 $75.22 $971,993 126,307 Direct -9.28% Disposed -20.4% (price as of 2026-08-21)
Sept. 30, 2025 IONS S 10b5-1 49,800 $65.26 $3,249,948 110,500 Direct -31.07% Disposed -8.2% (price as of 2026-08-21)
Jan. 31, 2025 IONS S 1,523 $32.44 $49,406 110,500 Direct -1.36% Disposed 84.6% (price as of 2026-08-21)
Jan. 16, 2025 IONS S 8,870 $32.81 $291,025 107,885 Direct -7.60% Disposed 82.5% (price as of 2026-08-21)
Feb. 2, 2024 IONS S 2,162 $49.54 $107,105 92,868 Direct -2.28% Disposed 20.9% (price as of 2026-08-21)
Feb. 2, 2024 IONS S 2,125 $49.54 $105,272 92,905 Direct -2.24% Disposed 20.9% (price as of 2026-08-21)
Jan. 17, 2024 IONS S 8,683 $50.42 $437,797 90,890 Direct -8.72% Disposed 18.8% (price as of 2026-08-21)
Feb. 6, 2023 IONS S 2,079 $40.59 $84,387 75,496 Direct -2.68% Disposed 47.5% (price as of 2026-08-21)
Jan. 18, 2023 IONS S 8,280 $39.70 $328,716 73,435 Direct -10.13% Disposed 50.8% (price as of 2026-08-21)
Nov. 25, 2020 IONS S 10b5-1 21,680 $50.05 $1,085,084 32,495 Direct -40.02% Disposed 19.6% (price as of 2026-08-21)
Nov. 24, 2020 IONS S 10b5-1 4,320 $50.83 $219,586 32,495 Direct -11.73% Disposed 17.8% (price as of 2026-08-21)
Nov. 23, 2020 IONS S 10b5-1 5,875 $50.11 $294,396 32,495 Direct -15.31% Disposed 19.5% (price as of 2026-08-21)
Nov. 23, 2020 IONS S 10b5-1 13,125 $50.11 $657,694 32,495 Direct -28.77% Disposed 19.5% (price as of 2026-08-21)
Dec. 4, 2019 IONS S 10b5-1 4,062 $65.00 $264,030 20,055 Direct -16.84% Disposed -7.9% (price as of 2026-08-21)
Dec. 4, 2019 IONS S 10b5-1 504 $65.00 $32,760 20,055 Direct -2.45% Disposed -7.9% (price as of 2026-08-21)
Nov. 25, 2019 IONS S 10b5-1 4,000 $62.50 $250,000 20,055 Direct -16.63% Disposed -4.2% (price as of 2026-08-21)

Showing latest 100 of 253 transactions

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II)

Options, RSUs and convertible securities reported on Form 4 Table II.

Date Ticker Security Underlying Exercise price Expiration Shares A/D
March 16, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (33,118) $32.60 Jan. 2, 2032 33,118 Disposed
March 16, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (20,541) $37.58 Jan. 2, 2033 20,541 Disposed
March 16, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (61,041) $56.78 Jan. 3, 2028 61,041 Disposed
March 16, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (60,299) $60.89 Jan. 1, 2027 60,299 Disposed
Jan. 15, 2026 IONS Restricted Stock Unit [F8] Common Stock (12,885) — — 12,885 Acquired
Jan. 15, 2026 IONS Restricted Stock Unit Common Stock (28,729) — — 28,729 Disposed
Jan. 15, 2026 IONS Performance Restricted Stock Units [F4] Common Stock (34,360) $0.00 — 34,360 Acquired
Jan. 2, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (25,770) $79.67 Jan. 1, 2036 25,770 Acquired
Sept. 30, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (49,800) $53.77 Jan. 1, 2026 49,800 Disposed
June 24, 2025 ARTV Director Stock Option (Right to Buy) Common Stock (13,750) $1.61 June 23, 2035 13,750 Acquired
Jan. 15, 2025 IONS Restricted Stock Unit Common Stock (23,887) — — 23,887 Disposed
Jan. 15, 2025 IONS Restricted Stock Unit [F6] Common Stock (46,500) — — 46,500 Acquired
Jan. 15, 2025 IONS Performance Restricted Stock Units [F4] Common Stock (31,000) $0.00 — 31,000 Acquired
Jan. 2, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (31,000) $34.69 Jan. 1, 2035 31,000 Acquired
Jan. 16, 2024 IONS Restricted Stock Unit Common Stock (22,487) — — 22,487 Disposed
Jan. 15, 2024 IONS Restricted Stock Unit [F3] Common Stock (32,400) — — 32,400 Acquired
Jan. 15, 2024 IONS Performance Restricted Stock Units [F1] Common Stock (27,000) $0.00 — 27,000 Acquired
Jan. 2, 2024 IONS Non-Qualified Stock Option (right to buy) Common Stock (43,200) $52.87 Jan. 1, 2034 43,200 Acquired
Dec. 28, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (45,225) $47.34 Jan. 2, 2024 45,225 Disposed
Jan. 17, 2023 IONS Restricted Stock Unit Common Stock (23,154) — — 23,154 Disposed
Jan. 15, 2023 IONS Restricted Stock Unit [F3] Common Stock (19,460) — — 19,460 Acquired
Jan. 15, 2023 IONS Performance Restricted Stock Units [F1] Common Stock (16,216) $0.00 — 16,216 Acquired
Jan. 3, 2023 IONS Non-Qualified Stock Option (right to buy) Common Stock (25,946) $37.58 Jan. 2, 2033 25,946 Acquired
Jan. 18, 2022 IONS Restricted Stock Unit Common Stock (22,050) — — 22,050 Disposed
Jan. 15, 2022 IONS Restricted Stock Unit [F3] Common Stock (16,559) — — 16,559 Acquired
Jan. 15, 2022 IONS Performance Restricted Stock Units [F1] Common Stock (12,419) $0.00 — 12,419 Acquired
Jan. 3, 2022 IONS Non-Qualified Stock Option (right to buy) Common Stock (33,118) $32.60 Jan. 2, 2032 33,118 Acquired
Jan. 15, 2021 IONS Restricted Stock Units Common Stock (27,129) — — 27,129 Acquired
Jan. 15, 2021 IONS Restricted Stock Units Common Stock (17,151) — — 17,151 Disposed
Jan. 4, 2021 IONS Employee Stock Option (right to buy) Common Stock (61,041) $56.78 Jan. 3, 2028 61,041 Acquired
Nov. 25, 2020 IONS Non-Qualified Stock Option (right to buy) Common Stock (0) $39.87 Jan. 1, 2021 21,680 Disposed
Nov. 24, 2020 IONS Non-Qualified Stock Option (right to buy) Common Stock (0) $39.87 Jan. 1, 2021 4,320 Disposed
Nov. 23, 2020 IONS Non-Qualified Stock Option (right to buy) Common Stock (0) $39.87 Jan. 1, 2021 5,875 Disposed
Nov. 23, 2020 IONS Non-Qualified Stock Option (right to buy) Common Stock (0) $39.87 Jan. 1, 2021 13,125 Disposed
Jan. 15, 2020 IONS Restricted Stock Units Common Stock (12,044) — — 12,044 Disposed
Jan. 15, 2020 IONS Restricted Stock Units Common Stock (26,800) — — 26,800 Acquired
Jan. 2, 2020 IONS Employee Stock Option (right to buy) Common Stock (60,299) $60.89 Jan. 1, 2027 60,299 Acquired
Dec. 20, 2019 IONS Employee Stock Option (right to buy) Common Stock (3,438) $10.82 Jan. 1, 2020 3,438 Disposed
Dec. 20, 2019 IONS Employee Stock Option (right to buy) Common Stock (7,196) $10.82 Jan. 1, 2020 7,196 Disposed
Dec. 4, 2019 IONS Employee Stock Option (right to buy) Common Stock (4,062) $10.82 Jan. 1, 2020 4,062 Disposed
Dec. 4, 2019 IONS Employee Stock Option (right to buy) Common Stock (504) $10.82 Jan. 1, 2020 504 Disposed
Nov. 25, 2019 IONS Employee Stock Option (right to buy) Common Stock (4,000) $10.82 Jan. 1, 2020 4,000 Disposed
Nov. 19, 2019 IONS Employee Stock Option (right to buy) Common Stock (4,000) $10.82 Jan. 1, 2020 4,000 Disposed
Jan. 15, 2019 IONS Restricted Stock Units Common Stock (7,891) — — 7,891 Disposed
Jan. 15, 2019 IONS Restricted Stock Units Common Stock (22,131) — — 22,131 Acquired
Jan. 2, 2019 IONS Employee Stock Option (right to buy) Common Stock (49,800) $53.77 Jan. 1, 2026 49,800 Acquired
Dec. 19, 2018 IONS Employee Stock Option (right to buy) Common Stock (2,063) $7.25 Jan. 2, 2019 2,063 Acquired
Dec. 18, 2018 IONS Employee Stock Option (right to buy) Common Stock (2,000) $7.25 Jan. 2, 2019 2,000 Acquired
Jan. 15, 2018 IONS Restricted Stock Units Common Stock (6,732) — — 6,732 Disposed
Jan. 15, 2018 IONS Restricted Stock Units Common Stock (12,137) — — 12,137 Acquired
Jan. 2, 2018 IONS Employee Stock Option (right to buy) Common Stock (54,619) $49.25 Jan. 1, 2025 54,619 Acquired
Dec. 15, 2017 IONS Employee Stock Option (right to buy) Common Stock (5,000) $10.29 Jan. 2, 2018 5,000 Disposed
Dec. 4, 2017 IONS Employee Stock Option (right to buy) Common Stock (4,000) $10.29 Jan. 2, 2018 4,000 Disposed
Nov. 29, 2017 IONS Employee Stock Option (right to buy) Common Stock (6,000) $10.29 Jan. 2, 2018 6,000 Disposed
Nov. 16, 2017 IONS Employee Stock Option (right to buy) Common Stock (7,000) $10.29 Jan. 2, 2018 7,000 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (1,594) — — 1,594 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (1,380) — — 1,380 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (1,875) — — 1,875 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (653) — — 653 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (312) — — 312 Disposed
Jan. 15, 2017 IONS Restricted Stock Units Common Stock (7,537) — — 7,537 Acquired
Jan. 3, 2017 IONS Employee Stock Option (right to buy) Common Stock (45,225) $47.34 Jan. 2, 2024 45,225 Acquired
Dec. 5, 2016 IONS Employee Stock Option (right to buy) Common Stock (2,500) $11.27 Jan. 3, 2017 2,500 Disposed
Nov. 14, 2016 IONS Employee Stock Option (right to buy) Common Stock (2,500) $11.27 Jan. 3, 2017 2,500 Disposed
Nov. 11, 2016 IONS Employee Stock Option (right to buy) Common Stock (2,500) $11.27 Jan. 3, 2017 2,500 Disposed
Nov. 9, 2016 IONS Employee Stock Option (right to buy) Common Stock (2,500) $11.27 Jan. 3, 2017 2,500 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (1,380) — — 1,380 Disposed
Jan. 15, 2016 IONS Restricted Stock Unit Common Stock (1,875) — — 1,875 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (654) — — 654 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (312) — — 312 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (541) — — 541 Disposed
Jan. 15, 2016 IONS Restricted Stock Units Common Stock (6,373) — — 6,373 Acquired
Jan. 4, 2016 IONS Employee Stock Option (right to buy) Common Stock (38,240) $61.68 Jan. 3, 2023 38,240 Acquired
March 19, 2015 IONS Employee Stock Option (right to buy) Common Stock (10,000) $11.27 Jan. 3, 2017 10,000 Disposed
March 5, 2015 IONS Employee Stock Option (right to buy) Common Stock (15,437) $7.25 Jan. 2, 2019 15,437 Disposed
March 5, 2015 IONS Employee Stock Option (right to buy) Common Stock (12,657) $14.47 Jan. 2, 2016 12,657 Disposed
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (5,518) — — 5,518 Acquired
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (541) — — 541 Disposed
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (313) — — 313 Disposed
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (654) — — 654 Disposed
Jan. 15, 2015 IONS Restricted Stock Units Common Stock (1,875) — — 1,875 Disposed
Jan. 2, 2015 IONS Employee Stock Option (right to buy) Common Stock (33,112) $61.57 Jan. 1, 2022 33,112 Acquired
Jan. 15, 2014 IONS Restricted Stock Units Common Stock (313) — — 313 Disposed
Jan. 15, 2014 IONS Restricted Stock Units Common Stock (542) — — 542 Disposed
Jan. 15, 2014 IONS Restricted Stock Units Common Stock (654) — — 654 Disposed
Jan. 15, 2014 IONS Restricted Stock Units Common Stock (7,500) — — 7,500 Acquired
Jan. 2, 2014 IONS Employee Stock Option (right to buy) Common Stock (45,000) $39.87 Jan. 1, 2021 45,000 Acquired
April 24, 2013 IONS Employee Stock Option (right to buy) Common Stock (10,417) $15.38 Jan. 1, 2015 10,417 Disposed
April 22, 2013 IONS Employee Stock Option (right to buy) Common Stock (7,813) $15.38 Jan. 1, 2015 7,813 Disposed
April 22, 2013 IONS Employee Stock Option (right to buy) Common Stock (9,843) $14.47 Jan. 1, 2016 9,843 Disposed
March 20, 2013 IONS Employee Stock Option (right to buy) Common Stock (4,792) $11.12 Dec. 31, 2013 4,792 Disposed
March 20, 2013 IONS Employee Stock Option (right to buy) Common Stock (9,584) $11.12 Jan. 1, 2014 9,584 Disposed
March 5, 2013 IONS Employee Stock Option (right to buy) Common Stock (5,040) $6.81 Jan. 1, 2014 5,040 Disposed
Jan. 15, 2013 IONS Restricted Stock Units Common Stock (2,615) — — 2,615 Acquired
Jan. 15, 2013 IONS Restricted Stock Units Common Stock (1,250) — — 1,250 Acquired
Jan. 15, 2013 IONS Restricted Stock Units Common Stock — — 542 Disposed
Jan. 2, 2013 IONS Employee Stock Option (right to buy) Common Stock (7,500) $10.82 Jan. 1, 2020 7,500 Acquired
Jan. 2, 2013 IONS Employee Stock Option (right to buy) Common Stock (15,700) $10.82 Jan. 1, 2020 15,700 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 12 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date Ticker Security Shares Ownership
July 18, 2024 ARTV Director Stock Option (right to buy)→ Common Stock (13,679) 13,679 Direct
July 18, 2024 ARTV Director Stock Option (right to buy)→ Common Stock (3,419) 3,419 Direct
Jan. 3, 2013 IONS No securities are beneficially owned 0 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (5,040) 5,040 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (4,792) 4,792 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (9,584) 9,584 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (18,230) 18,230 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (22,500) 22,500 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (20,000) 20,000 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (22,000) 22,000 Direct
Jan. 3, 2013 IONS Employee Stock Option (right to buy)→ Common Stock (19,500) 19,500 Direct
Jan. 3, 2013 IONS Restricted Stock Units→ Common Stock (2,166) 2,166 Direct