Insider at

04

Insider transactions

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0 buys (P) 0 sells (S) Net: $0 + 2 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

No open-market trades on record; showing all filings.

DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Dec. 9, 2008 ALNY A 15,000 · · 15,000 Direct · Acquired (price as of 2026-10-05)
Sept. 29, 2008 ALNY A 200,000 · · 200,000 Direct · Acquired (price as of 2026-10-05)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

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DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
Dec. 9, 2008 ALNY Stock Option (right to buy) Common Stock (15,000) $21.35 Dec. 8, 2018 15,000 Acquired
Sept. 29, 2008 ALNY Stock Option (right to buy) Common Stock (200,000) $30.25 Sept. 28, 2018 200,000 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 1 holding

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Oct. 1, 2008 ALNY Stock Option (right to buy)→ Common Stock (200,000) 200,000 Direct