Karen A Dawes

CIK 1261506 · View on SEC EDGAR ↗

Insider

First SEC filing: Sept. 19, 2005 · Latest: Feb. 10, 2023

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Insider at

Insider transactions

0 buys (P) 1 sells (S) Net: $-44,275 + 35 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

35 other filings hidden
Date Ticker Code Shares Price Value Owned after Δ own A/D vs now
Dec. 17, 2025 RGEN S 275 $161.00 $44,275 91,821 Direct -0.30% Disposed 9.7% (price as of 2026-08-21)
Feb. 27, 2024 RGEN S 1,000 $193.35 $193,350 87,367 Direct -1.13% Disposed -8.6% (price as of 2026-08-21)
Aug. 29, 2023 RGEN S 850 $171.38 $145,673 83,741 Direct -1.00% Disposed 3.1% (price as of 2026-08-21)
Sept. 9, 2022 RGEN S 775 $227.17 $176,057 76,401 Direct -1.00% Disposed -22.2% (price as of 2026-08-21)
May 25, 2022 RGEN S 742 $152.84 $113,407 76,532 Direct -0.96% Disposed 15.6% (price as of 2026-08-21)
May 25, 2022 RGEN S 1,875 $152.14 $285,262 77,274 Direct -2.37% Disposed 16.1% (price as of 2026-08-21)
May 25, 2022 RGEN S 1,845 $151.14 $278,853 79,149 Direct -2.28% Disposed 16.9% (price as of 2026-08-21)
May 25, 2022 RGEN S 7,677 $150.19 $1,153,009 80,994 Direct -8.66% Disposed 17.6% (price as of 2026-08-21)
May 25, 2022 RGEN S 2,576 $149.18 $384,288 88,671 Direct -2.82% Disposed 18.4% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 1,038 $262.28 $272,247 94,294 Direct -1.09% Disposed -32.7% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 1,119 $263.23 $294,554 93,175 Direct -1.19% Disposed -32.9% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 336 $264.21 $88,775 92,839 Direct -0.36% Disposed -33.1% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 488 $265.27 $129,452 92,351 Direct -0.53% Disposed -33.4% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 486 $266.72 $129,626 91,865 Direct -0.53% Disposed -33.8% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 14 $271.28 $3,798 91,247 Direct -0.02% Disposed -34.9% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 255 $269.94 $68,835 91,261 Direct -0.28% Disposed -34.6% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 349 $267.75 $93,445 91,516 Direct -0.38% Disposed -34.0% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 236 $261.10 $61,620 95,332 Direct -0.25% Disposed -32.3% (price as of 2026-08-21)
Nov. 10, 2021 RGEN S 462 $259.75 $120,004 95,568 Direct -0.48% Disposed -32.0% (price as of 2026-08-21)
Nov. 2, 2021 RGEN S 283 $306.49 $86,737 91,247 Direct -0.31% Disposed -42.4% (price as of 2026-08-21)
Nov. 2, 2021 RGEN S 700 $305.91 $214,137 91,530 Direct -0.76% Disposed -42.3% (price as of 2026-08-21)
Nov. 2, 2021 RGEN S 124 $304.23 $37,725 92,230 Direct -0.13% Disposed -41.9% (price as of 2026-08-21)
Nov. 2, 2021 RGEN S 532 $303.48 $161,451 92,354 Direct -0.57% Disposed -41.8% (price as of 2026-08-21)
Nov. 2, 2021 RGEN S 446 $301.97 $134,679 92,886 Direct -0.48% Disposed -41.5% (price as of 2026-08-21)
Nov. 2, 2021 RGEN S 251 $301.20 $75,601 93,332 Direct -0.27% Disposed -41.4% (price as of 2026-08-21)
Nov. 2, 2021 RGEN S 64 $299.02 $19,137 93,583 Direct -0.07% Disposed -40.9% (price as of 2026-08-21)
Sept. 14, 2021 RGEN S 27 $295.82 $7,987 93,647 Direct -0.03% Disposed -40.3% (price as of 2026-08-21)
Sept. 14, 2021 RGEN S 108 $295.02 $31,862 93,674 Direct -0.12% Disposed -40.1% (price as of 2026-08-21)
Sept. 14, 2021 RGEN S 101 $294.06 $29,700 93,782 Direct -0.11% Disposed -39.9% (price as of 2026-08-21)
Sept. 14, 2021 RGEN S 25 $292.34 $7,308 93,883 Direct -0.03% Disposed -39.6% (price as of 2026-08-21)
Sept. 14, 2021 RGEN S 13 $290.02 $3,770 93,908 Direct -0.01% Disposed -39.1% (price as of 2026-08-21)
Sept. 1, 2021 RGEN S 851 $285.44 $242,909 93,921 Direct -0.90% Disposed -38.1% (price as of 2026-08-21)
Sept. 1, 2021 RGEN S 1,107 $284.64 $315,096 94,772 Direct -1.15% Disposed -37.9% (price as of 2026-08-21)
Sept. 1, 2021 RGEN S 661 $283.56 $187,433 95,879 Direct -0.68% Disposed -37.7% (price as of 2026-08-21)
Sept. 1, 2021 RGEN S 405 $282.53 $114,425 96,540 Direct -0.42% Disposed -37.5% (price as of 2026-08-21)
Sept. 1, 2021 RGEN S 196 $281.68 $55,209 96,945 Direct -0.20% Disposed -37.3% (price as of 2026-08-21)
Sept. 1, 2021 RGEN S 239 $280.27 $66,985 97,141 Direct -0.25% Disposed -37.0% (price as of 2026-08-21)
Aug. 18, 2021 RGEN S 40 $262.31 $10,492 93,921 Direct +0.04% Acquired -32.7% (price as of 2026-08-21)
Aug. 18, 2021 RGEN S 78 $260.91 $20,351 93,961 Direct -0.08% Disposed -32.3% (price as of 2026-08-21)
Aug. 18, 2021 RGEN S 388 $259.93 $100,853 94,039 Direct -0.41% Disposed -32.0% (price as of 2026-08-21)
Aug. 18, 2021 RGEN S 634 $258.91 $164,149 94,427 Direct -0.67% Disposed -31.8% (price as of 2026-08-21)
Aug. 18, 2021 RGEN S 302 $257.66 $77,813 95,061 Direct -0.32% Disposed -31.4% (price as of 2026-08-21)
Aug. 17, 2021 RGEN S 194 $256.43 $49,747 95,363 Direct -0.20% Disposed -31.1% (price as of 2026-08-21)
Aug. 17, 2021 RGEN S 2,231 $255.07 $569,061 95,557 Direct -2.28% Disposed -30.7% (price as of 2026-08-21)
Aug. 17, 2021 RGEN S 8,580 $254.09 $2,180,092 97,788 Direct -8.07% Disposed -30.5% (price as of 2026-08-21)
Aug. 17, 2021 RGEN S 4,665 $253.34 $1,181,831 106,368 Direct -4.20% Disposed -30.3% (price as of 2026-08-21)
Aug. 17, 2021 RGEN S 920 $251.92 $231,766 111,033 Direct -0.82% Disposed -29.9% (price as of 2026-08-21)
Aug. 17, 2021 RGEN S 924 $251.15 $232,063 111,953 Direct -0.82% Disposed -29.7% (price as of 2026-08-21)
July 20, 2021 RGEN S 614 $203.11 $124,710 112,877 Direct -0.54% Disposed -13.0% (price as of 2026-08-21)
July 20, 2021 RGEN S 2,877 $202.29 $581,988 113,491 Direct -2.47% Disposed -12.7% (price as of 2026-08-21)
July 20, 2021 RGEN S 806 $201.37 $162,304 116,368 Direct -0.69% Disposed -12.3% (price as of 2026-08-21)
July 20, 2021 RGEN S 288 $200.01 $57,603 117,174 Direct -0.25% Disposed -11.7% (price as of 2026-08-21)
July 13, 2021 RGEN S 441 $201.27 $88,760 118,541 Direct -0.37% Disposed -12.2% (price as of 2026-08-21)
July 13, 2021 RGEN S 630 $202.29 $127,443 117,911 Direct -0.53% Disposed -12.7% (price as of 2026-08-21)
July 13, 2021 RGEN S 5 $204.02 $1,020 117,462 Direct 0.00% Disposed -13.4% (price as of 2026-08-21)
July 13, 2021 RGEN S 444 $203.09 $90,172 117,467 Direct -0.38% Disposed -13.0% (price as of 2026-08-21)
July 13, 2021 RGEN S 1,520 $202.23 $307,390 117,462 Direct +1.31% Acquired -12.7% (price as of 2026-08-21)
May 11, 2021 RGEN S 285 $176.85 $50,402 115,449 Direct -0.25% Disposed -0.1% (price as of 2026-08-21)
May 4, 2021 BRNS P 1,700 $17.00 $28,900 1,700 Direct Acquired -96.3% (price as of 2026-08-21)
June 18, 2020 RGEN S 2,568 $116.56 $299,326 100,734 Direct -2.49% Disposed 51.5% (price as of 2026-08-21)
June 18, 2020 RGEN S 8,217 $115.76 $951,200 103,302 Direct -7.37% Disposed 52.6% (price as of 2026-08-21)
June 18, 2020 RGEN S 5,243 $114.49 $600,271 111,519 Direct -4.49% Disposed 54.3% (price as of 2026-08-21)
June 18, 2020 RGEN S 2,677 $113.58 $304,054 116,762 Direct -2.24% Disposed 55.5% (price as of 2026-08-21)
April 20, 2020 RGEN S 3,202 $104.98 $336,146 118,032 Direct -2.64% Disposed 68.3% (price as of 2026-08-21)
April 20, 2020 RGEN S 8,998 $104.42 $939,571 109,034 Direct -7.62% Disposed 69.2% (price as of 2026-08-21)

Showing latest 100 of 172 transactions

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II)

Options, RSUs and convertible securities reported on Form 4 Table II.

Date Ticker Security Underlying Exercise price Expiration Shares A/D
May 14, 2026 RGEN Stock Option (Right to Buy) Common Stock (2,239) $103.38 May 14, 2036 2,239 Acquired
May 15, 2025 RGEN Stock Option (Right to Buy) Common Stock (1,800) $123.26 May 15, 2035 1,800 Acquired
June 14, 2024 RGEN Stock Option (Right to Buy) Common Stock (2,953) $67.71 May 15, 2029 2,953 Acquired
May 16, 2024 RGEN Stock Option (Right to Buy) Common Stock (1,576) $171.03 May 16, 2034 1,576 Acquired
Feb. 27, 2024 RGEN Stock Option (Right to Buy) Common Stock (4,626) $42.07 May 16, 2028 4,626 Acquired
Aug. 29, 2023 RGEN Stock Option (Right to Buy) Common Stock (7,392) $18.12 May 15, 2024 7,392 Acquired
May 18, 2023 RGEN Stock Option (Right to Buy) Common Stock (1,730) $156.63 May 18, 2033 1,730 Acquired
May 11, 2023 BRNS Share Option (Right to Buy) Ordinary Shares [F2] (19,197) $2.27 May 11, 2033 19,197 Acquired
May 26, 2022 RGEN Stock Option (Right to Buy) Common Stock (1,565) $159.17 May 26, 2032 1,565 Acquired
Nov. 10, 2021 RGEN Stock Option (Right to Buy) Common Stock (4,783) $26.12 May 11, 2026 4,783 Acquired
Sept. 1, 2021 RGEN Stock Option (Right to Buy) Common Stock (3,459) $38.76 May 18, 2027 3,459 Acquired
July 13, 2021 RGEN Stock Option (Right to Buy) Common Stock (2,929) $41.19 July 21, 2025 2,929 Acquired
July 13, 2021 RGEN Stock Option (Right to Buy) Common Stock (2,929) $41.19 July 21, 2025 2,929 Acquired
May 13, 2021 RGEN Stock Option (Right to Buy) Common Stock (1,522) $169.65 May 13, 2031 1,522 Acquired
May 11, 2021 RGEN Stock Option (Right to Buy) Common Stock (15,000) $3.22 Dec. 15, 2021 15,000 Disposed
April 29, 2021 BRNS Share Option (Right to Buy) Ordinary Shares [F1] (34,328) $17.00 April 29, 2031 34,328 Acquired
May 13, 2020 RGEN Stock Option (Right to Buy) Common Stock (1,761) $128.18 May 13, 2030 1,761 Acquired
May 13, 2020 RGEN Stock Option (Right to Buy) Common Stock (1,761) $128.18 May 13, 2030 1,761 Acquired
April 21, 2020 RGEN Stock Option (Right to Buy) Common Stock (11,800) $3.30 Sept. 16, 2020 11,800 Disposed
April 21, 2020 RGEN Stock Option (Right to Buy) Common Stock (11,800) $3.30 Sept. 16, 2020 11,800 Disposed
April 20, 2020 RGEN Stock Option (Right to Buy) Common Stock (8,200) $3.30 Sept. 16, 2020 8,200 Disposed
April 20, 2020 RGEN Stock Option (Right to Buy) Common Stock (8,200) $3.30 Sept. 16, 2020 8,200 Disposed
June 17, 2019 RGEN Stock Options (Right to Buy) Common Stock (20,000) $4.96 Sept. 11, 2019 20,000 Disposed
May 15, 2019 RGEN Stock Option (Right to Buy) Common Stock (2,953) $67.71 May 15, 2029 2,953 Acquired
May 16, 2018 RGEN Stock Option (Right to Buy) Common Stock (4,626) $42.07 May 16, 2028 4,626 Acquired
May 11, 2018 RGEN Stock Option (Right to Buy) Common Stock (20,000) $5.08 Sept. 12, 2018 20,000 Disposed
May 18, 2017 RGEN Stock Option (Right to Buy) Common Stock (3,459) $38.76 May 18, 2027 3,459 Acquired
March 21, 2017 RGEN Stock Option (Right to Buy) Common Stock (20,000) $4.29 Sept. 14, 2017 20,000 Disposed
June 27, 2016 RGEN Stock Option (Right to Buy) Common Stock (15,000) $3.10 Sept. 15, 2016 15,000 Disposed
May 11, 2016 RGEN Stock Option (Right to Buy) Common Stock (4,783) $26.12 May 11, 2026 4,783 Acquired
May 21, 2015 RGEN Stock Option (Right to Buy) Common Stock (2,929) $41.19 May 21, 2025 2,929 Acquired
May 15, 2014 RGEN Stock Option (Right to Buy) Common Stock (7,392) $18.12 May 15, 2024 7,392 Acquired
Dec. 15, 2011 RGEN Stock Option (Right to Buy) Common Stock (15,000) $3.22 Dec. 15, 2021 15,000 Acquired
Sept. 16, 2010 RGEN Stock Option (Right to Buy) Common Stock (20,000) $3.30 Sept. 16, 2020 20,000 Acquired
Sept. 11, 2009 RGEN Stock Option (Right to Buy) Common Stock (20,000) $4.96 Sept. 11, 2019 20,000 Acquired
Sept. 12, 2008 RGEN Stock Option (Right to Buy) Common Stock (20,000) $5.08 Sept. 12, 2018 20,000 Acquired
Sept. 14, 2007 RGEN Stock Option (Right to Buy) Common Stock (20,000) $4.29 Sept. 14, 2017 20,000 Acquired
Sept. 15, 2006 RGEN Stock Option (Right to Buy) Common Stock (15,000) $3.10 Sept. 15, 2016 15,000 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 2 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date Ticker Security Shares Ownership
Sept. 19, 2005 RGEN Stock Option(Right to Buy)→ Common Stock (15,000) 15,000 Direct
Sept. 19, 2005 RGEN Stock Option (Right to Buy)→ Common Stock (24,000) 24,000 Direct