Insider at

04

Insider transactions

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0 buys (P) 4 sells (S) Net: $-3,334,240 + 17 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

17 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
April 16, 2026 IONS S 4,902 $75.17 $368,483 23,713 Direct -17.13% Disposed -42.1% (price as of 2026-10-02)
March 10, 2026 IONS S 10b5-1 16,086 $76.30 $1,227,362 11,714 Direct -57.86% Disposed -42.9% (price as of 2026-10-02)
March 10, 2026 IONS S 10b5-1 21,191 $75.50 $1,599,920 27,800 Direct -43.25% Disposed -42.3% (price as of 2026-10-02)
Jan. 16, 2026 IONS S 1,823 $75.96 $138,475 16,389 Direct -10.01% Disposed -42.7% (price as of 2026-10-02)
April 16, 2025 IONS S 3,016 $28.36 $85,534 11,199 Direct -21.22% Disposed 53.5% (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

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DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
April 15, 2026 IONS Restricted Stock Unit Common Stock (12,226) · · 12,226 Disposed
March 10, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (32,602) $46.10 Feb. 25, 2034 32,602 Disposed
March 10, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (4,675) $34.69 Jan. 1, 2035 4,675 Disposed
Jan. 15, 2026 IONS Restricted Stock Unit Common Stock (7,013) · · 7,013 Disposed
Jan. 15, 2026 IONS Restricted Stock Unit [F6] Common Stock (9,675) · · 9,675 Acquired
Jan. 15, 2026 IONS Performance Restricted Stock Units [F4] Common Stock (25,800) $0.00 · 25,800 Acquired
Jan. 2, 2026 IONS Non-Qualified Stock Option (right to buy) Common Stock (19,350) $79.67 Jan. 1, 2036 19,350 Acquired
April 15, 2025 IONS Restricted Stock Unit Common Stock (12,226) · · 12,226 Disposed
Jan. 15, 2025 IONS Restricted Stock Unit [F3] Common Stock (28,050) · · 28,050 Acquired
Jan. 15, 2025 IONS Performance Restricted Stock Units [F1] Common Stock (18,700) $0.00 · 18,700 Acquired
Jan. 2, 2025 IONS Non-Qualified Stock Option (right to buy) Common Stock (18,700) $34.69 Jan. 1, 2035 18,700 Acquired
Feb. 26, 2024 IONS Non-Qualified Stock Option (right to buy) Common Stock (65,203) $46.10 Feb. 25, 2034 65,203 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 1 holding

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Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
March 13, 2024 IONS Common Stock 1,989 Direct