Insider at

04

Insider transactions

05
0 buys (P) 0 sells (S) Net: $0 + 13 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

13 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Aug. 11, 2008 IONS S 10b5-1 10,000 $18.95 $189,500 0 Direct -100.00% Disposed 129.8% (price as of 2026-10-02)
Aug. 11, 2008 IONS S 10b5-1 10,000 $17.96 $179,600 10,000 Direct -50.00% Disposed 142.4% (price as of 2026-10-02)
Sept. 21, 2007 IONS S 10b5-1 10,000 $14.95 $149,500 0 Direct -100.00% Disposed 191.2% (price as of 2026-10-02)
Sept. 14, 2007 IONS S 10b5-1 10,000 $13.96 $139,600 0 Direct -100.00% Disposed 211.9% (price as of 2026-10-02)
July 12, 2007 IONS S 10b5-1 10,000 $11.95 $119,500 0 Direct -100.00% Disposed 264.4% (price as of 2026-10-02)
July 10, 2007 IONS S 10b5-1 10,000 $11.95 $119,500 0 Direct -100.00% Disposed 264.4% (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
Aug. 11, 2008 IONS Employee Stock Option (right to buy) Common Stock (20,000) $5.95 Dec. 5, 2011 20,000 Disposed
Jan. 2, 2008 IONS Employee Stock Option (right to buy) Common Stock (21,840) $15.38 Jan. 1, 2015 21,840 Acquired
Sept. 21, 2007 IONS Employee Stock Option (right to buy) Common Stock (10,000) $5.95 Dec. 5, 2011 10,000 Disposed
Sept. 14, 2007 IONS Employee Stock Option (right to buy) Common Stock (10,000) $5.95 Dec. 5, 2011 10,000 Disposed
July 12, 2007 IONS Employee Stock Option (right to buy) Common Stock (10,000) $5.95 Dec. 5, 2011 10,000 Disposed
July 10, 2007 IONS Employee Stock Option (right to buy) Common Stock (10,000) $5.25 Jan. 2, 2013 10,000 Disposed
Jan. 2, 2007 IONS Employee Stock Option (right to buy) Common Stock (41,110) $11.12 Jan. 1, 2014 41,110 Acquired
Jan. 3, 2006 IONS Employee Stock Option (right to buy) Common Stock (40,842) $5.25 Jan. 2, 2013 40,842 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 2 holdings

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Dec. 21, 2004 IONS No securities beneficially owned 0 Direct
Dec. 21, 2004 IONS Employee Stock Option (right to buy)→ Common Stock (90,000) 90,000 Direct

Compensation (DEF 14A)

08

Matched by name from proxy statements (DEF 14A) — verify against the filing.

IONS

Vice President,
Fiscal yearSalaryBonusStock awards Option awardsNon-equity incentivePension changeOtherTotal
2007 $356,131 $256,414 · $232,093 · · $11,583 $856,221
2006 $340,795 $146,201 · $173,127 · · $11,142 $671,265

Figures from the Summary Compensation Table of the company's proxy statement (DEF 14A). Compensation is not a recommendation.