Insider at

04

Insider transactions

05
0 buys (P) 0 sells (S) Net: $0 + 24 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

No open-market trades on record; showing all filings.

DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
May 14, 2026 RARE A 7,751 · · 40,441 Direct +23.71% Acquired (price as of 2026-10-02)
May 14, 2026 RARE A 14,058 · · 14,058 Direct · Acquired (price as of 2026-10-02)
May 15, 2025 RARE A 10,787 · · 10,787 Direct · Acquired (price as of 2026-10-02)
May 15, 2025 RARE A 5,740 · · 32,690 Direct +21.30% Acquired (price as of 2026-10-02)
June 18, 2024 RARE A 9,900 · · 9,900 Direct · Acquired (price as of 2026-10-02)
June 18, 2024 RARE A 5,345 · · 26,950 Direct +24.74% Acquired (price as of 2026-10-02)
June 7, 2023 RARE A 7,110 · · 7,110 Direct · Acquired (price as of 2026-10-02)
June 7, 2023 RARE A 3,860 · · 21,605 Direct +21.75% Acquired (price as of 2026-10-02)
June 24, 2022 RARE A 6,245 · · 6,245 Direct · Acquired (price as of 2026-10-02)
June 24, 2022 RARE A 3,300 · · 17,745 Direct +22.85% Acquired (price as of 2026-10-02)
June 24, 2021 RARE A 4,125 · · 4,125 Direct · Acquired (price as of 2026-10-02)
June 24, 2021 RARE A 2,145 · · 14,445 Direct +17.44% Acquired (price as of 2026-10-02)
June 26, 2020 RARE A 4,250 · · 4,250 Direct · Acquired (price as of 2026-10-02)
June 26, 2020 RARE A 2,550 · · 12,300 Direct +26.15% Acquired (price as of 2026-10-02)
June 11, 2019 RARE A 5,000 · · 5,000 Direct · Acquired (price as of 2026-10-02)
June 11, 2019 RARE A 3,000 · · 9,750 Direct +44.44% Acquired (price as of 2026-10-02)
June 19, 2018 RARE A 5,000 · · 5,000 Direct · Acquired (price as of 2026-10-02)
June 19, 2018 RARE A 3,000 · · 6,750 Direct +80.00% Acquired (price as of 2026-10-02)
June 22, 2017 RARE A 3,750 · · 3,750 Direct · Acquired (price as of 2026-10-02)
June 22, 2017 RARE A 1,875 · · 3,750 Direct +100.00% Acquired (price as of 2026-10-02)
June 9, 2016 RARE A 1,875 · · 1,875 Direct · Acquired (price as of 2026-10-02)
June 9, 2016 RARE A 3,750 · · 3,750 Direct · Acquired (price as of 2026-10-02)
June 18, 2015 RARE A 7,500 · · 7,500 Direct · Acquired (price as of 2026-10-02)
Feb. 20, 2015 RARE A 17,500 · · 17,500 Direct · Acquired (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
May 14, 2026 RARE Stock Option (Right to Buy) Common Stock (14,058) $25.80 May 14, 2036 14,058 Acquired
May 15, 2025 RARE Stock Option (Right to Buy) Common Stock (10,787) $34.84 May 15, 2035 10,787 Acquired
June 18, 2024 RARE Stock Option (Right to Buy) Common Stock (9,900) $37.42 June 18, 2034 9,900 Acquired
June 7, 2023 RARE Common Stock Common Stock (7,110) $51.82 June 7, 2033 7,110 Acquired
June 24, 2022 RARE Stock Option (Right to Buy) Common Stock (6,245) $60.57 June 24, 2032 6,245 Acquired
June 24, 2021 RARE Stock Option (Right to Buy) Common Stock (4,125) $93.20 June 24, 2031 4,125 Acquired
June 26, 2020 RARE Stock Option (Right to Buy) Common Stock (4,250) $76.58 June 26, 2030 4,250 Acquired
June 11, 2019 RARE Stock Option (Right to Buy) Common Stock (5,000) $58.74 June 11, 2029 5,000 Acquired
June 19, 2018 RARE Stock Option (Right to Buy) Common Stock (5,000) $80.69 June 19, 2028 5,000 Acquired
June 22, 2017 RARE Employee Stock Option (Right to Buy) Common Stock (3,750) $65.66 June 22, 2027 3,750 Acquired
June 9, 2016 RARE Employee Stock Option (Right to Buy) Common Stock (3,750) $65.85 June 9, 2026 3,750 Acquired
June 18, 2015 RARE Stock Option (Right to Buy) Common Stock (7,500) $97.85 June 17, 2025 7,500 Acquired
Feb. 20, 2015 RARE Stock Option (Right to Buy) Common Stock (17,500) $55.57 Feb. 19, 2025 17,500 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).