Opaleye Management Inc.
CIK 1595855 · View on SEC EDGAR ↗
Insider
First SEC filing: June 11, 2026 · Latest: June 11, 2026
On this page
Institution
Insider at
Insider transactions
22 buys (P)
9 sells (S)
Net:
$-3,290,581
+ 1 non-open-market transaction below
Avg return of open purchases vs now:
32.4%
last 12 months, based on the transactions shown below
Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted
1 other filing hidden
| Date | Ticker | Code | Shares | Price | Value | Owned after | Δ own | A/D | vs now |
|---|---|---|---|---|---|---|---|---|---|
| Aug. 14, 2026 | GRCE | P | 11,608 | $2.09 | $24,261 | 2,760,000 Indirect | +0.42% | Acquired | 5.0% (price as of 2026-08-21) |
| Aug. 12, 2026 | SLGL | P | 951 | $71.50 | $67,996 | 494,887 Indirect | +0.19% | Acquired | 14.6% (price as of 2026-08-21) |
| Aug. 3, 2026 | ACOG | P | 50,000 | $8.00 | $400,000 | 3,048,223 Indirect | +1.67% | Acquired | 25.9% (price as of 2026-08-21) |
| July 31, 2026 | ACOG | P | 2,900 | $7.92 | $22,968 | 2,998,223 Indirect | +0.10% | Acquired | 27.2% (price as of 2026-08-21) |
| July 24, 2026 | ACOG | P | 130 | $7.90 | $1,027 | 2,995,323 Indirect | 0.00% | Acquired | 27.5% (price as of 2026-08-21) |
| July 23, 2026 | ACOG | P | 49,849 | $7.80 | $388,822 | 2,995,193 Indirect | +1.69% | Acquired | 29.2% (price as of 2026-08-21) |
| July 22, 2026 | ACOG | P | 10,000 | $7.83 | $78,300 | 100,000 Indirect | +11.11% | Acquired | 28.7% (price as of 2026-08-21) |
| July 22, 2026 | ACOG | P | 140,237 | $7.83 | $1,098,056 | 2,945,344 Indirect | +5.00% | Acquired | 28.7% (price as of 2026-08-21) |
| July 14, 2026 | ETON | S | 13,315 | $37.54 | $499,845 | 40,000 Indirect | -24.97% | Disposed | 62.3% (price as of 2026-08-21) |
| July 14, 2026 | ETON | S | 15,000 | $37.54 | $563,100 | 2,665,000 Indirect | -0.56% | Disposed | 62.3% (price as of 2026-08-21) |
| July 14, 2026 | ETON | S | 13,315 | $37.54 | $499,845 | 40,000 Indirect | -24.97% | Disposed | 62.3% (price as of 2026-08-21) |
| July 14, 2026 | ETON | S | 15,000 | $37.54 | $563,100 | 2,665,000 Indirect | -0.56% | Disposed | 62.3% (price as of 2026-08-21) |
| July 14, 2026 | SLGL | P | 920 | $73.43 | $67,556 | 493,936 Indirect | +0.19% | Acquired | 11.6% (price as of 2026-08-21) |
| July 13, 2026 | SLGL | P | 775 | $73.89 | $57,265 | 493,016 Indirect | +0.16% | Acquired | 10.9% (price as of 2026-08-21) |
| July 10, 2026 | SLGL | P | 229 | $73.95 | $16,935 | 492,241 Indirect | +0.05% | Acquired | 10.8% (price as of 2026-08-21) |
| July 8, 2026 | SLGL | P | 300 | $73.69 | $22,107 | 492,012 Indirect | +0.06% | Acquired | 11.2% (price as of 2026-08-21) |
| July 7, 2026 | ETON | S | 6,685 | $38.37 | $256,503 | 53,315 Indirect | -11.14% | Disposed | 58.8% (price as of 2026-08-21) |
| July 7, 2026 | ETON | S | 20,000 | $38.37 | $767,400 | 2,680,000 Indirect | -0.74% | Disposed | 58.8% (price as of 2026-08-21) |
| July 6, 2026 | ETON | S | 10,000 | $38.00 | $380,000 | 2,700,000 Indirect | -0.37% | Disposed | 60.4% (price as of 2026-08-21) |
| July 2, 2026 | ETON | S | 25,000 | $37.39 | $934,750 | 60,000 Indirect | -29.41% | Disposed | 63.0% (price as of 2026-08-21) |
| July 2, 2026 | ETON | S | 65,000 | $37.39 | $2,430,350 | 2,710,000 Indirect | -2.34% | Disposed | 63.0% (price as of 2026-08-21) |
| July 2, 2026 | SLGL | P | 1,400 | $71.97 | $100,758 | 491,712 Indirect | +0.29% | Acquired | 13.8% (price as of 2026-08-21) |
| July 1, 2026 | SLGL | P | 312 | $71.99 | $22,461 | 490,312 Indirect | +0.06% | Acquired | 13.8% (price as of 2026-08-21) |
| June 26, 2026 | ACOG | P | 152,336 | $6.40 | $974,950 | 2,805,107 Indirect | +5.74% | Acquired | 57.4% (price as of 2026-08-21) |
| June 25, 2026 | ACOG | P | 197 | $6.50 | $1,280 | 2,652,771 Indirect | +0.01% | Acquired | 55.0% (price as of 2026-08-21) |
| June 15, 2026 | ACOG | P | 4,550 | $5.99 | $27,254 | 2,652,574 Indirect | +0.17% | Acquired | 68.2% (price as of 2026-08-21) |
| June 12, 2026 | ACOG | P | 273 | $5.93 | $1,619 | 2,648,024 Indirect | +0.01% | Acquired | 69.9% (price as of 2026-08-21) |
| June 11, 2026 | ACOG | P | 2,862 | $5.91 | $16,914 | 2,647,751 Indirect | +0.11% | Acquired | 70.5% (price as of 2026-08-21) |
| June 9, 2026 | ACOG | P | 24,856 | $5.98 | $148,534 | 2,644,889 | — | — | 68.5% (price as of 2026-08-21) |
| June 5, 2026 | 1595855 | P | 10,054 | $5.83 | $58,596 | 2,614,161 | — | — | |
| May 27, 2026 | 1595855 | P | 1,161 | $5.73 | $6,653 | 2,604,107 | — | — | |
| Nov. 10, 2023 | 1595855 | S | 4,324,008 | $0.29 | $1,272,123 | 0 | — | — | |
| March 9, 2023 | 1595855 | P | 174,508 | $1.38 | $240,821 | 4,324,508 | — | — | |
| Dec. 14, 2022 | 1595855 | P | 140,000 | $1.26 | $175,826 | 440,000 | — | — | |
| Dec. 6, 2022 | 1595855 | S | 1,539 | $1.44 | $2,216 | 4,010,000 | — | — | |
| Oct. 18, 2022 | 1595855 | P | 10,000 | $1.65 | $16,500 | 4,125,000 | — | — | |
| Sept. 29, 2022 | 1595855 | P | 9,400 | $1.74 | $16,370 | 410,000 | — | — | |
| Sept. 27, 2022 | 1595855 | P | 1,700 | $1.69 | $2,877 | 400,600 | — | — | |
| Sept. 22, 2022 | 1595855 | P | 3,411 | $1.73 | $5,900 | 398,900 | — | — | |
| Sept. 20, 2022 | 1595855 | P | 10,000 | $1.85 | $18,524 | 385,000 | — | — | |
| Sept. 19, 2022 | 1595855 | P | 5,000 | $1.87 | $9,366 | 375,000 | — | — | |
| July 26, 2022 | 1595855 | P | 2,254 | $1.72 | $3,877 | 370,000 | — | — | |
| July 15, 2022 | 1595855 | P | 11,826 | $1.78 | $21,068 | 367,746 | — | — | |
| July 14, 2022 | 1595855 | P | 7,187 | $1.81 | $13,024 | 355,920 | — | — | |
| June 24, 2022 | 1595855 | P | 11,419 | $1.39 | $15,894 | 348,733 | — | — | |
| June 21, 2022 | 1595855 | P | 841,989 | $1.31 | $1,105,279 | 3,776,589 | — | — | |
| May 10, 2022 | 1595855 | P | 8,500 | $1.76 | $14,925 | 337,314 | — | — | |
| April 29, 2022 | 1595855 | P | 6,100 | $1.98 | $12,078 | 336,114 | — | — | |
| April 22, 2022 | 1595855 | P | 37,704 | $2.24 | $84,333 | 335,114 | — | — | |
| April 13, 2022 | 1595855 | P | 5,000 | $2.50 | $12,499 | 330,041 | — | — | |
| April 11, 2022 | 1595855 | P | 6,463 | $2.42 | $15,639 | 325,000 | — | — | |
| March 16, 2022 | 1595855 | P | 2,235 | $2.20 | $4,917 | 2,837,735 | — | — | |
| Jan. 28, 2022 | 1595855 | P | 500 | $2.20 | $1,100 | 2,820,500 | — | — | |
| Jan. 21, 2022 | 1595855 | P | 30,000 | $2.19 | $65,838 | 317,363 | — | — | |
| Jan. 19, 2022 | 1595855 | P | 20,000 | $2.24 | $44,816 | 310,000 | — | — | |
| Dec. 29, 2021 | 1595855 | P | 32,325 | $2.51 | $81,152 | 305,000 | — | — | |
| Dec. 27, 2021 | 1595855 | P | 75,000 | $2.92 | $219,098 | 285,000 | — | — | |
| Dec. 1, 2021 | 1595855 | P | 20,000 | $2.43 | $48,522 | 252,675 | — | — | |
| Dec. 1, 2021 | 1595855 | P | 14,000 | $2.64 | $36,974 | 250,711 | — | — | |
| Dec. 1, 2021 | 1595855 | P | 80,000 | $2.30 | $183,624 | 242,507 | — | — | |
| Dec. 1, 2021 | 1595855 | P | 45,000 | $2.40 | $108,144 | 230,500 | — | — | |
| Dec. 22, 2020 | 1595855 | P | 496,277 | $8.06 | $3,999,993 | 2,293,371 | — | — | |
| Oct. 21, 2020 | 1595855 | P | 3,000 | $4.40 | $13,191 | 1,797,094 | — | — | |
| Sept. 23, 2020 | 1595855 | P | 2,200 | $4.83 | $10,633 | 1,785,438 | — | — | |
| Sept. 4, 2020 | 1595855 | P | 566 | $2.88 | $1,633 | 1,709,438 | — | — | |
| Sept. 1, 2020 | 1595855 | P | 1,400 | $2.04 | $2,862 | 1,655,946 | — | — | |
| Aug. 27, 2020 | 1595855 | P | 147,946 | $1.71 | $252,514 | 1,502,346 | — | — |
P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding
Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.
Initial ownership (Form 3) 17 holdings
Securities held when first becoming an insider, per SEC Form 3.
| Date | Ticker | Security | Shares | Ownership |
|---|---|---|---|---|
| Feb. 20, 2026 | ACOG | Common Stock, no par value | 2,193,589 | Indirect |
| Feb. 20, 2026 | ACOG | Common Stock, no par value | 75,000 | Indirect |
| Feb. 20, 2026 | ACOG | Common Stock, no par value | 2,125,000 | Indirect |
| Feb. 20, 2026 | ACOG | Common Stock, no par value | 68,589 | Indirect |
| Nov. 17, 2025 | SLGL | Ordinary Shares, par value NIS 1.00 per share | 357,367 | Indirect |
| Nov. 17, 2025 | SLGL | Ordinary Shares, par value NIS 1.00 per share | 10,000 | Indirect |
| Sept. 12, 2024 | ETON | Common Stock, par value $0.001 per share | 2,610,000 | Indirect |
| Sept. 12, 2024 | ETON | Common Stock, par value $0.001 per share | 62,500 | Indirect |
| May 22, 2020 | HROW | Common Stock, $0.001 par value | 2,480,500 | Indirect |
| May 22, 2020 | HROW | Common Stock, $0.001 par value | 118,600 | Indirect |
| April 6, 2020 | ETON | Common Stock, $0.001 par value | 3,500,000 | Indirect |
| April 6, 2020 | ETON | Common Stock, $0.001 par value | 140,000 | Indirect |
| Dec. 27, 2019 | OCUL | Common Stock, $0.0001 par value | 4,888,500 | Indirect |
| Dec. 27, 2019 | OCUL | Common Stock, $0.0001 par value | 202,500 | Indirect |
| Dec. 27, 2019 | OCUL | American-style call option→ Common Stock (1,000) | 1,000 | Direct |
| May 20, 2015 | HROW | Imprimis Pharmaceuticals, Inc. | 1,167,199 | Indirect |
| May 20, 2015 | HROW | Imprimis Pharmaceuticals, Inc. | 1,167,199 | Indirect |