Orlov S Nicole Schaeffer

Insider

First SEC filing: June 4, 2014 · Latest: June 4, 2014

On this page

Insider at Companies where this person is a reporting insider.
Insider transactions Every share this person bought or sold, from Form 4 filings.
Derivatives Options and other derivative holdings reported by this person.
Initial holdings The stakes this person held when they first started reporting.

Insider at

INSM selling Jan. 2, 2026

Insider transactions

0 buys (P) 9 sells (S) Net: $-26,423,350 + 62 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

62 other filings hidden

Date	Ticker	Code	Shares	Price	Value	Owned after	Δ own	A/D	vs now
Jan. 2, 2026	INSM	A	5,293	—	—	41,754 Direct	+14.52%	Acquired	(price as of 2026-08-21)
Jan. 2, 2026	INSM	M 10b5-1	87,290	$13.91	$1,214,204	129,044 Direct	+209.06%	Acquired	801.6% (price as of 2026-08-21)
Jan. 2, 2026	INSM	S 10b5-1	31,030	$174.28	$5,407,908	98,014 Direct	-24.05%	Disposed	-28.0% (price as of 2026-08-21)
Jan. 2, 2026	INSM	S 10b5-1	34,103	$175.17	$5,973,823	63,911 Direct	-34.79%	Disposed	-28.4% (price as of 2026-08-21)
Jan. 2, 2026	INSM	S 10b5-1	12,832	$176.08	$2,259,459	51,079 Direct	-20.08%	Disposed	-28.8% (price as of 2026-08-21)
Jan. 2, 2026	INSM	S 10b5-1	9,125	$177.17	$1,616,676	41,954 Direct	-17.86%	Disposed	-29.2% (price as of 2026-08-21)
Jan. 2, 2026	INSM	S 10b5-1	200	$177.78	$35,556	41,754 Direct	-0.48%	Disposed	-29.5% (price as of 2026-08-21)
Jan. 2, 2026	INSM	A	27,600	—	—	27,600 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 2, 2026	INSM	M 10b5-1	87,290	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-21)
Sept. 12, 2025	INSM	M 10b5-1	56,520	$23.75	$1,342,350	112,981 Direct	+100.10%	Acquired	428.0% (price as of 2026-08-21)
Sept. 12, 2025	INSM	S 10b5-1	32,091	$144.60	$4,640,359	80,890 Direct	-28.40%	Disposed	-13.3% (price as of 2026-08-21)
Sept. 12, 2025	INSM	S 10b5-1	30,967	$145.67	$4,510,963	49,923 Direct	-38.28%	Disposed	-13.9% (price as of 2026-08-21)
Sept. 12, 2025	INSM	S 10b5-1	7,304	$146.57	$1,070,547	42,619 Direct	-14.63%	Disposed	-14.4% (price as of 2026-08-21)
Sept. 12, 2025	INSM	S 10b5-1	6,158	$147.46	$908,059	36,461 Direct	-14.45%	Disposed	-15.0% (price as of 2026-08-21)
Sept. 12, 2025	INSM	M 10b5-1	56,520	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-21)
Sept. 4, 2025	INSM	G	23,303	—	—	56,461 Direct	-29.21%	Disposed	(price as of 2026-08-21)
Aug. 14, 2025	INSM	S	3,554	$126.57	$449,830	86,210 Direct	-3.96%	Disposed	-0.9% (price as of 2026-08-21)
Aug. 14, 2025	INSM	S	5,746	$127.71	$733,822	80,464 Direct	-6.67%	Disposed	-1.8% (price as of 2026-08-21)
Aug. 14, 2025	INSM	S	700	$128.16	$89,712	79,764 Direct	-0.87%	Disposed	-2.1% (price as of 2026-08-21)
Jan. 5, 2023	INSM	S	1,448	$19.73	$28,569	68,262 Direct	-2.08%	Disposed	535.6% (price as of 2026-08-21)
Jan. 5, 2023	INSM	A	6,332	—	—	74,594 Direct	+9.28%	Acquired	(price as of 2026-08-21)
Jan. 5, 2023	INSM	A	29,050	—	—	29,050 Direct	—	Acquired	(price as of 2026-08-21)
May 17, 2022	INSM	S	1,670	$20.27	$33,851	68,822 Direct	-2.37%	Disposed	518.7% (price as of 2026-08-21)
May 16, 2022	INSM	S	1,114	$18.41	$20,509	70,492 Direct	-1.56%	Disposed	581.2% (price as of 2026-08-21)
May 11, 2022	INSM	A	69,060	—	—	69,060 Direct	—	Acquired	(price as of 2026-08-21)
May 11, 2022	INSM	A	14,645	—	—	71,606 Direct	+25.71%	Acquired	(price as of 2026-08-21)
Jan. 11, 2022	INSM	S	925	$25.11	$23,227	56,961 Direct	-1.60%	Disposed	399.4% (price as of 2026-08-21)
Jan. 6, 2022	INSM	A	45,700	—	—	45,700 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 6, 2022	INSM	A	9,458	—	—	57,886 Direct	+19.53%	Acquired	(price as of 2026-08-21)
Jan. 6, 2022	INSM	S	1,612	$26.00	$41,912	48,428 Direct	-3.22%	Disposed	382.3% (price as of 2026-08-21)
Jan. 5, 2022	INSM	S	1,503	$27.61	$41,498	50,040 Direct	-2.92%	Disposed	354.2% (price as of 2026-08-21)
Nov. 1, 2021	INSM	M	25,000	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-21)
Nov. 1, 2021	INSM	M	36,000	—	—	25,000 Direct	-59.02%	Disposed	(price as of 2026-08-21)
Nov. 1, 2021	INSM	S 10b5-1	340	$31.08	$10,567	51,514 Direct	-0.66%	Disposed	303.5% (price as of 2026-08-21)
Nov. 1, 2021	INSM	S 10b5-1	60,660	$30.28	$1,836,785	51,854 Direct	-53.91%	Disposed	314.2% (price as of 2026-08-21)
Nov. 1, 2021	INSM	M 10b5-1	61,000	$12.44	$758,840	112,514 Direct	+118.41%	Acquired	908.1% (price as of 2026-08-21)
May 15, 2021	INSM	F	1,806	$26.23	$47,371	50,792 Direct	-3.43%	Disposed	378.1% (price as of 2026-08-21)
May 12, 2021	INSM	A	45,760	—	—	45,760 Direct	—	Acquired	(price as of 2026-08-21)
May 12, 2021	INSM	A	9,448	—	—	52,598 Direct	+21.90%	Acquired	(price as of 2026-08-21)
March 8, 2021	INSM	M	4,709	$20.49	$96,487	45,629 Direct	+11.51%	Acquired	512.1% (price as of 2026-08-21)
March 8, 2021	INSM	F	2,479	$38.92	$96,483	43,150 Direct	-5.43%	Disposed	222.2% (price as of 2026-08-21)
March 8, 2021	INSM	M	4,709	—	—	22,791 Direct	+26.04%	Acquired	(price as of 2026-08-21)
Jan. 7, 2021	INSM	A	36,480	—	—	36,480 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 7, 2021	INSM	A	7,346	—	—	40,920 Direct	+21.88%	Acquired	(price as of 2026-08-21)
Jan. 4, 2021	INSM	F	910	$33.42	$30,412	33,574 Direct	-2.64%	Disposed	275.3% (price as of 2026-08-21)
Jan. 3, 2021	INSM	F	949	$33.29	$31,592	34,484 Direct	-2.68%	Disposed	276.7% (price as of 2026-08-21)
Aug. 12, 2020	INSM	M	4,000	—	—	8,500 Direct	-32.00%	Disposed	(price as of 2026-08-21)
Aug. 12, 2020	INSM	M	465	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-21)
Aug. 12, 2020	INSM	S	4,000	$28.80	$115,200	35,227 Direct	-10.20%	Disposed	335.5% (price as of 2026-08-21)
Aug. 12, 2020	INSM	M	4,000	$12.44	$49,760	39,227 Direct	+11.35%	Acquired	908.1% (price as of 2026-08-21)
Aug. 12, 2020	INSM	S	465	$28.77	$13,378	35,227 Direct	-1.30%	Disposed	335.9% (price as of 2026-08-21)
Aug. 12, 2020	INSM	M	465	$6.96	$3,236	35,692 Direct	+1.32%	Acquired	1701.9% (price as of 2026-08-21)
Aug. 11, 2020	INSM	M	3,761	—	—	465 Direct	-89.00%	Disposed	(price as of 2026-08-21)
Aug. 11, 2020	INSM	S	3,761	$30.07	$113,093	35,227 Direct	-9.65%	Disposed	317.1% (price as of 2026-08-21)
Aug. 11, 2020	INSM	M	3,761	$6.96	$26,177	38,988 Direct	+10.68%	Acquired	1701.9% (price as of 2026-08-21)
May 15, 2020	INSM	F	1,126	$25.46	$28,668	35,227 Direct	-3.10%	Disposed	392.6% (price as of 2026-08-21)
Jan. 3, 2020	INSM	A	56,520	—	—	56,520 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 3, 2020	INSM	F	979	$23.75	$23,251	35,552 Direct	-2.68%	Disposed	428.0% (price as of 2026-08-21)
Jan. 3, 2020	INSM	A	10,526	—	—	36,531 Direct	+40.48%	Acquired	(price as of 2026-08-21)
June 6, 2019	INSM	M	12,000	—	—	4,226 Direct	-73.96%	Disposed	(price as of 2026-08-21)
June 6, 2019	INSM	S	12,000	$23.24	$278,880	24,350 Direct	-33.01%	Disposed	439.6% (price as of 2026-08-21)
June 6, 2019	INSM	M	12,000	$6.96	$83,520	36,350 Direct	+49.28%	Acquired	1701.9% (price as of 2026-08-21)
May 15, 2019	INSM	A	14,660	—	—	24,350 Direct	+151.29%	Acquired	(price as of 2026-08-21)
Jan. 4, 2019	INSM	F	979	$14.85	$14,538	9,690 Direct	-9.18%	Disposed	744.5% (price as of 2026-08-21)
Jan. 3, 2019	INSM	A	157,290	—	—	157,290 Direct	—	Acquired	(price as of 2026-08-21)
Sept. 28, 2018	INSM	A	12,500	—	—	12,500 Direct	—	Acquired	(price as of 2026-08-21)
May 30, 2018	INSM	M	25,991	—	—	37,575 Direct	-40.89%	Disposed	(price as of 2026-08-21)
May 30, 2018	INSM	S	25,991	$28.24	$733,986	10,669 Direct	-70.90%	Disposed	344.1% (price as of 2026-08-21)
May 30, 2018	INSM	M	25,991	$10.85	$282,002	36,660 Direct	+243.61%	Acquired	1055.9% (price as of 2026-08-21)
May 29, 2018	INSM	M	11,584	—	—	63,566 Direct	-15.41%	Disposed	(price as of 2026-08-21)
May 29, 2018	INSM	S	11,584	$27.68	$320,645	10,669 Direct	-52.06%	Disposed	353.1% (price as of 2026-08-21)
May 29, 2018	INSM	M	11,584	$10.85	$125,686	22,253 Direct	+108.58%	Acquired	1055.9% (price as of 2026-08-21)
Jan. 4, 2018	INSM	A	55,400	—	—	55,400 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 4, 2018	INSM	A	10,669	—	—	10,669 Direct	—	Acquired	(price as of 2026-08-21)
May 17, 2017	INSM	A	38,300	—	—	38,300 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 5, 2017	INSM	A	41,140	—	—	41,140 Direct	—	Acquired	(price as of 2026-08-21)
Nov. 9, 2016	INSM	M	8,009	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-21)
Nov. 9, 2016	INSM	S	8,009	$13.25	$106,119	0 Direct	-100.00%	Disposed	846.5% (price as of 2026-08-21)
Nov. 9, 2016	INSM	M	8,009	$6.96	$55,743	8,009 Direct	—	Acquired	1701.9% (price as of 2026-08-21)
Nov. 7, 2016	INSM	M	23,265	—	—	8,009 Direct	-74.39%	Disposed	(price as of 2026-08-21)
Nov. 7, 2016	INSM	M	37,500	—	—	16,226 Direct	-69.80%	Disposed	(price as of 2026-08-21)
Nov. 7, 2016	INSM	S	23,265	$11.78	$274,062	0 Direct	-100.00%	Disposed	964.6% (price as of 2026-08-21)
Nov. 7, 2016	INSM	M	23,265	$6.96	$161,924	23,265 Direct	—	Acquired	1701.9% (price as of 2026-08-21)
Nov. 7, 2016	INSM	S	37,500	$11.78	$441,750	0 Direct	-100.00%	Disposed	964.6% (price as of 2026-08-21)
Nov. 7, 2016	INSM	M	37,500	$6.96	$261,000	37,500 Direct	—	Acquired	1701.9% (price as of 2026-08-21)
May 19, 2016	INSM	A	75,150	—	—	75,150 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 7, 2016	INSM	A	50,000	—	—	50,000 Direct	—	Acquired	(price as of 2026-08-21)
May 21, 2015	INSM	A	41,250	$22.76	$938,850	41,250 Direct	—	Acquired	451.0% (price as of 2026-08-21)
Feb. 26, 2015	INSM	A	12,500	—	—	12,500 Direct	—	Acquired	(price as of 2026-08-21)
Jan. 8, 2015	INSM	A	13,750	—	—	13,750 Direct	—	Acquired	(price as of 2026-08-21)
June 2, 2014	INSM	A	27,500	$12.58	$345,950	27,500 Direct	—	Acquired	896.9% (price as of 2026-08-21)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II)

Options, RSUs and convertible securities reported on Form 4 Table II.

Date	Ticker	Security	Underlying	Exercise price	Expiration	Shares	A/D
Jan. 2, 2026	INSM	Stock Option (right to buy)	Common Stock (27,600)	$177.12	Jan. 2, 2036	27,600	Acquired
Jan. 2, 2026	INSM	Stock Option (right to buy)	Common Stock (87,290)	$13.91	Jan. 3, 2029	87,290	Disposed
Sept. 12, 2025	INSM	Stock Option (right to buy)	Common Stock (56,520)	$23.75	Jan. 3, 2030	56,520	Disposed
Jan. 5, 2023	INSM	Stock Option (right to buy)	Common Stock (29,050)	$19.74	Jan. 5, 2033	29,050	Acquired
May 11, 2022	INSM	Stock Option (right to buy)	Common Stock (69,060)	$17.07	May 11, 2032	69,060	Acquired
Jan. 6, 2022	INSM	Stock Option (right to buy)	Common Stock (45,700)	$26.43	Jan. 6, 2032	45,700	Acquired
Nov. 1, 2021	INSM	Stock Option (right to buy)	Common Stock (25,000)	$12.44	May 23, 2023	25,000	Disposed
Nov. 1, 2021	INSM	Stock Option (right to buy)	Common Stock (36,000)	$12.44	May 23, 2023	36,000	Disposed
May 12, 2021	INSM	Stock Option (right to buy)	Common Stock (45,760)	$26.46	May 12, 2031	45,760	Acquired
March 8, 2021	INSM	Stock Option (right to buy)	Common Stock (4,709)	$20.49	Jan. 4, 2024	4,709	Acquired
Jan. 7, 2021	INSM	Stock Option (right to buy)	Common Stock (36,480)	$34.03	Jan. 7, 2031	36,480	Acquired
Aug. 12, 2020	INSM	Stock Option (right to buy)	Common Stock (4,000)	$12.44	May 23, 2023	4,000	Disposed
Aug. 12, 2020	INSM	Stock Option (right to buy)	Common Stock (465)	$6.96	Jan. 2, 2023	465	Disposed
Aug. 11, 2020	INSM	Stock Option (right to buy)	Common Stock (3,761)	$6.96	Jan. 2, 2023	3,761	Disposed
Jan. 3, 2020	INSM	Stock Option (right to buy)	Common Stock (56,520)	$23.75	Jan. 3, 2030	56,520	Acquired
June 6, 2019	INSM	Stock Option (right to buy)	Common Stock (12,000)	$6.96	Jan. 2, 2023	12,000	Disposed
Jan. 3, 2019	INSM	Stock Option	Common Stock (157,290)	$13.91	Jan. 3, 2029	157,290	Acquired
Sept. 28, 2018	INSM	Stock Option	Common Stock	$12.44	May 23, 2023	12,500	Acquired
May 30, 2018	INSM	Stock Option (right to buy)	Common Stock (25,991)	$10.85	May 19, 2026	25,991	Disposed
May 29, 2018	INSM	Stock Option (right to buy)	Common Stock (11,584)	$10.85	May 19, 2026	11,584	Disposed
Jan. 4, 2018	INSM	Stock Option	Common Stock (55,400)	$30.46	Jan. 4, 2028	55,400	Acquired
May 17, 2017	INSM	Stock Option	Common Stock (38,300)	$17.16	May 17, 2027	38,300	Acquired
Jan. 5, 2017	INSM	Stock Option	Common Stock (41,140)	$13.67	Jan. 5, 2027	41,140	Acquired
Nov. 9, 2016	INSM	Stock Option	Common Stock (8,009)	$6.96	Jan. 2, 2023	8,009	Disposed
Nov. 7, 2016	INSM	Stock Option	Common Stock (23,265)	$6.96	Jan. 2, 2023	23,265	Disposed
Nov. 7, 2016	INSM	Stock Option	Common Stock (37,500)	$6.96	Jan. 2, 2023	37,500	Disposed
May 19, 2016	INSM	Stock Option	Common Stock (75,150)	$10.85	May 19, 2026	75,150	Acquired
Jan. 7, 2016	INSM	Stock Option	Common Stock (50,000)	$16.16	Jan. 7, 2026	50,000	Acquired
May 21, 2015	INSM	Stock Option	Common Stock (41,250)	$22.76	May 21, 2025	41,250	Acquired
Feb. 26, 2015	INSM	Stock Option	Common Stock (12,500)	$12.44	May 23, 2023	12,500	Acquired
Jan. 8, 2015	INSM	Stock Option	Common Stock (13,750)	$16.07	Jan. 8, 2025	13,750	Acquired
June 2, 2014	INSM	Stock Option	Common Stock (27,500)	$12.58	June 2, 2024	27,500	Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 4 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date	Ticker	Security	Shares	Ownership
June 4, 2014	INSM	Stock Option→ Common Stock (85,000)	85,000	Direct
June 4, 2014	INSM	Stock Option→ Common Stock (40,000)	40,000	Direct
June 4, 2014	INSM	Stock Option→ Common Stock (25,000)	25,000	Direct
June 4, 2014	INSM	Stock Option→ Common Stock (27,500)	27,500	Direct