CRSP CRISPR Therapeutics AG - Common Shares

NASDAQ · Biotechnology · SEC EDGAR'da Görüntüle ↗
$56,87
Fiyat · Ağu 19, 2026
Temel veriler itibarıyla Ağu 3, 2026

CRISPR Therapeutics AG - Common Shares Hakkında Wikipedia'dan şirket genel bakışı

CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. The company does business as CRISPR Therapeutics, Inc. in the United States. It was one of the first companies formed to utilize the CRISPR gene editing platform to develop medicines for the treatment of various rare and common diseases. The company has approximately 500 employees and has offices in Zug, Switzerland; Boston, Massachusetts; San Francisco, California; and London, United Kingdom. Its manufacturing facility in Framingham, Massachusetts, won the Facilities of the Year Award (FOYA) award in 2022. The company’s lead program, exagamglogene autotemcel, or exa-cel, was granted regulatory approval by the US Food and Drug Administration (FDA) in December 2023.

Devamını oku

CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. The company does business as CRISPR Therapeutics, Inc. in the United States. It was one of the first companies formed to utilize the CRISPR gene editing platform to develop medicines for the treatment of various rare and common diseases. The company has approximately 500 employees and has offices in Zug, Switzerland; Boston, Massachusetts; San Francisco, California; and London, United Kingdom. Its manufacturing facility in Framingham, Massachusetts, won the Facilities of the Year Award (FOYA) award in 2022. The company’s lead program, exagamglogene autotemcel, or exa-cel (formerly CTX001), was granted regulatory approval by the US Food and Drug Administration (FDA) in December 2023.

History

CRISPR Therapeutics was founded in 2013 by Emmanuelle Charpentier, Shaun Foy and Rodger Novak. Charpentier later shared the Nobel Prize in Chemistry in 2020 with Jennifer Doudna. As part of a working group, she provided the first scientific documentation on the development and use of CRISPR gene editing. This allows DNA to be specifically modified and edited, which can be used to ameliorate diseases. CRISPR Therapeutics is applying this technology platform to research, develop and commercialize medicines for various diseases including sickle cell disease, beta thalassemia, various cancers, type 1 diabetes, and cardiovascular diseases. The CEO is Samarth Kulkarni, PhD, who joined the company in 2015 as chief business officer. Kulkarni became CEO in 2017.

CRISPR Therapeutics has formed collaborations in support of its mission of developing medicines. Vertex Pharmaceuticals and CRISPR Therapeutics entered into a strategic research collaboration in 2015 focused on the use of CRISPR/Cas9 to discover and develop potential new treatments aimed at the underlying genetic causes of human disease. One of the first treatments to emerge from the joint research program was CTX001 or exagamglogene autotemcel (commonly known as Exa-cel). Subsequently, CRISPR Therapeutics and Vertex expanded their collaboration to include diseases like Duchenne muscular dystrophy and type 1 diabetes. In 2016, the company signed an agreement with Bayer AG to operate Casebia Therapeutics as a joint venture with Bayer under the management of CRISPR Therapeutics. The company went public on the NASDAQ exchange in October 2016.

CRISPR Therapeutics has established partnerships with additional companies such as Viacyte (part of Vertex), Nkarta, Capsida, Curevac, and others.

Products

CRISPR Therapeutics has drugs approved and in development for blood diseases, cancer, diabetes, and other severe diseases.

Exa-cel

Exa-cel is a drug therapy for the treatment of the rare blood disorders beta thalassemia and sickle cell disease developed jointly with Vertex Pharmaceuticals, that received FDA approval for clinical use in December 2023. In May 2020, exa-cel had received orphan drug designation from the US Food and Drug Administration (FDA) for transfusion-dependent beta thalassemia and from the European Medicines Agency for sickle cell disease and transfusion-dependent beta thalassemia. As of 2022 Phase 3 clinical trial results supported the safety and efficacy of this treatment. The rolling Biologics License Applications (BLAs) were submitted to the FDA for exa-cel for sickle cell disease and transfusion-dependent beta thalassemia. EU and UK filings were completed in 2022, and the submissions were validated by European Medicines Agency and The Medicines and Healthcare products Regulatory Agency as of April 2023.

Kaynak: Wikipedia (İngilizce), CC BY-SA 4.0 · Wikipedia'da Görüntüle ↗

Wikidata ↗

CRSP Hisse Senedi Özeti Fiyat, piyasa değeri, P/E, EPS, ROE, borç/öz sermaye, 52 haftalık aralık

Fiyat
$56.87
Piyasa Değeri
$5.45B
P/E (TTM)
-8.8
EPS (TTM)
$-6.47
Gelir (TTM)
$4M
Temettü Verimi
ROE
-32.0%
D/E Borç/Özsermaye
52 Haftlık Aralık
$44 – $78

CRSP Hisse Senedi Fiyat Grafiği Teknik göstergeler ile günlük OHLCV — kaydır, yakınlaştır ve görünümünüzü özelleştirin

10 Yıllık Performans Gelir, net kar, marjlar ve EPS trendleri

Gelir ve Net Gelir $4M
10-point trend, -32.0%
2016-12-31 2025-12-31
Hisse Başına Kâr $-6.47
9-point trend, -278.4%
2017-12-31 2025-12-31
Serbest Nakit Akışı $-346M
10-point trend, -493.1%
2016-12-31 2025-12-31
Marjlar -16569.8%

Değerleme P/E, P/S, P/B, EV/EBITDA oranları — hisse senedi pahalı mı ucuz mu?

Metrik
5 Yıllık trend
CRSP
Akran Ortalaması
P/E (TTM)
5-point trend, -150.3%
-8.8
P/S (TTM) (F/S (TTM))
5-point trend, +22368.1%
1553.7
56.3
P/B (F/D)
5-point trend, +7.6%
2.8
3.0
Price / FCF (Fiyat / Serbest Nakit Akışı)
5-point trend, -213.9%
-15.8

Kârlılık Brüt, faaliyet ve net kâr marjları; ROE, ROA, ROIC

Metrik
5 Yıllık trend
CRSP
Akran Ortalaması
Operating Margin (Faaliyet Kâr Marjı)
5-point trend, -46483.3%
-18933.7%
Net Profit Margin (Net Kâr Marjı)
5-point trend, -40239.9%
-16569.8%
-1643.9%
ROA
5-point trend, -256.5%
-25.8%
-40.2%
ROE
5-point trend, -308.2%
-32.0%
-75.3%
ROIC
5-point trend, -324.7%
-34.8%

Finansal Sağlık Borç, likidite, solventlik — bilanço gücü

Metrik
5 Yıllık trend
CRSP
Akran Ortalaması
Current Ratio (Cari Oran)
5-point trend, -34.0%
13.3
6.7
Quick Ratio (Cari Oran)
5-point trend, -33.2%
13.2

Büyüme Gelir, EPS ve net gelir büyümesi: YOY, 3 Yıllık CAGR, 5 Yıllık CAGR

Metrik
5 Yıllık trend
CRSP
Akran Ortalaması
Revenue YoY (Gelir Yıllık Bazda)
5-point trend, -99.6%
-90.6%
Revenue CAGR 3Y (Gelir 3 Yıllık Bileşik Büyüme Oranı)
5-point trend, -99.6%
43.1%
Revenue CAGR 5Y (Gelir 5 Yıllık Bileşik Büyüme Oranı)
5-point trend, -99.6%
37.3%

Hisse Başı Metrikler Hisse Başı Kâr, hisse başına defter değeri, hisse başına nakit akışı, hisse başına temettü

Metrik
5 Yıllık trend
CRSP
Akran Ortalaması
EPS (Diluted) (Hisse Başına Kar (Seyreltilmiş))
5-point trend, -237.7%
$-6.47

Sermaye Verimliliği Aktif devir hızı, stok devir hızı, alacak devir hızı

Metrik
5 Yıllık trend
CRSP
Akran Ortalaması

CRSP Analist Uzlaşması Boğa ve ayı analist görüşleri, 12 aylık fiyat hedefi, yukarı yönlü potansiyel

AL 29 analist
  • Güçlü Al 6 20,7%
  • Al 11 37,9%
  • Tut 12 41,4%
  • Sat 0 0,0%
  • Güçlü Sat 0 0,0%

12 Aylık Fiyat Hedefi

18 analist · 2026-08-15
Medyan hedef $80.00 +40,7%
Ortalama hedef $87.56 +54,0%

Kazanç Geçmişi EPS gerçekleşen vs tahmin, sürpriz %, kazanma oranı, bir sonraki kazanç tarihi

Ort. Sürpriz
0.01%
Dönem EPS Gerçek EPS Tahmin Sürpriz
30 Haziran 2026 $-0.94 $-1.22 0.28%
31 Mart 2026 $-1.28 $-1.25 -0.03%
31 Aralık 2025 $-1.37 $-1.18 -0.19%
30 Eylül 2025 $-1.17 $-1.29 0.12%
30 Haziran 2025 $-1.29 $-1.45 0.16%
31 Mart 2025 $-1.58 $-1.28 -0.30%

Akran karşılaştırması (GICS alt sektörü) Anahtar metrikler sektördeki benzerlerine karşı

Hisse Sembolü Piyasa Değeri P/E Gelir YoY Net Kar Marjı ROE Brüt Kar Marjı
CRSP $5.03B -8.1 -90.6% -16569.8% -32.0%
MLTX -3.7 -60.5%
ACIU
ADCT $444M -3.2 14.8% -175.3% 74.1%

Tüm Temeller Tüm metrikler yıla göre — gelir tablosu, bilanço, nakit akışı

Gelir Tablosu 15
CRSP için Yıllık Gelir Tablosu verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Revenue 11-point trend, +1321.1% $4M $37M $371M $1M $915M $719.0K $290M $3M $41M $5M $247.0K
R&D Expense 11-point trend, +2165.2% $285M $310M $387M $462M $341M $221M $179M $114M $70M $42M $13M
SG&A Expense 11-point trend, +448.7% $74M $73M $76M $102M $100M $86M $63M $48M $36M $31M $13M
Operating Expenses 11-point trend, +2471.9% $668M $504M $594M $674M $541M $355M $243M $162M $106M $73M $26M
Operating Income 11-point trend, -2483.0% $-665M $-467M $-223M $-673M $374M $-354M $47M $-159M $-65M $-68M $-26M
Interest Income 3-point trend, +347.6% · $104M $76M $23M · · · · · · ·
Other Non-op 11-point trend, +541187.5% $87M $104M $72M $23M $6M $6M $26M $-1M $-197.0K $79M $16.0K
Pretax Income 11-point trend, -2138.4% $-578M $-363M $-151M $-650M $380M $-348M $67M $-164M $-67M $-23M $-26M
Income Tax 11-point trend, +51814.3% $4M $4M $3M $-325.0K $2M $809.0K $448.0K $553.0K $2M $484.0K $7.0K
Net Income 11-point trend, -2180.5% $-582M $-366M $-154M $-650M $378M $-349M $67M $-165M $-68M $-23M $-26M
EPS (Basic) 9-point trend, -278.4% $-6.47 $-4.34 $-1.94 $-8.36 $4.97 $-5.29 $1.23 $-3.44 $-1.71 · ·
EPS (Diluted) 9-point trend, -278.4% $-6.47 $-4.34 $-1.94 $-8.36 $4.70 $-5.29 $1.17 $-3.44 $-1.71 · ·
Shares (Basic) 9-point trend, +124.5% 89,925,109 84,359,126 79,220,930 77,746,575 75,948,686 65,949,672 54,392,304 47,964,368 40,057,365 · ·
Shares (Diluted) 9-point trend, +124.5% 89,925,109 84,359,126 79,220,930 77,746,575 80,393,496 65,949,672 56,932,798 47,964,368 40,057,365 · ·
EBITDA 10-point trend, -859.9% $-645M $-447M $-203M $-649M $391M $-345M $51M $-155M $-62M $-67M ·
Bilanço 25
CRSP için Yıllık Bilanço verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, +122.8% $348M $298M $389M $212M $923M $1.17B $944M $457M $240M $316M $156M
Short-term Investments 7-point trend, +1628269000.00 $1.63B $1.61B $1.30B $1.60B $1.46B $522M $0 · · · ·
Receivables 11-point trend, -100.0% $0 $25M $200M $0 $305.0K $144.0K $99.0K $88.0K $3M $3M $339.0K
Prepaid Expense 11-point trend, +1722.8% $10M $8M $14M $38M $38M $26M $44M $10M $6M $2M $540.0K
Current Assets 11-point trend, +1166.0% $1.99B $1.94B $1.91B $1.85B $2.42B $1.72B $988M $466M $248M $320M $157M
PP&E (Net) 11-point trend, +8623.7% $116M $134M $152M $164M $138M $42M $31M $18M $19M $21M $1M
PP&E (Gross) 11-point trend, +14678.8% $207M $206M $205M $197M $175M $63M $43M $26M $23M $22M $1M
Accum. Depreciation 11-point trend, +126361.1% $91M $72M $53M $34M $38M $21M $12M $7M $4M $942.0K $72.0K
Intangibles 10-point trend, -100.0% · $0 $16.0K $71.0K $125.0K $180.0K $235.0K $289.0K $344.0K $399.0K $454.0K
Other Non-current Assets 11-point trend, +24026.7% $24M $16M $2M $5M $5M $1M $1M $669.0K $606.0K $198.0K $101.0K
Total Assets 11-point trend, +1320.9% $2.27B $2.24B $2.23B $2.24B $2.75B $1.83B $1.07B $489M $271M $345M $159M
Accounts Payable 11-point trend, +603.2% $11M $15M $38M $27M $15M $9M $6M $5M $2M $5M $2M
Accrued Liabilities 11-point trend, +960.6% $89M $41M $45M $78M $91M $54M $30M $21M $11M $16M $8M
Current Liabilities 11-point trend, +1368.4% $149M $88M $109M $121M $120M $94M $57M $28M $15M $22M $10M
Capital Leases 7-point trend, +327.2% $188M $206M $223M $228M $213M $50M $44M · · · ·
Other Non-current Liabilities 11-point trend, +2085.8% $6M $3M $958.0K $6M $7M $8M $14M $243.0K $314.0K $189.0K $281.0K
Total Liabilities 11-point trend, +176.9% $343M $310M $347M $368M $352M $164M $127M $97M $84M $112M $124M
Long-term Debt $0 · · · · · · · · · ·
Common Stock 11-point trend, +1605.5% $3M $3M $2M $2M $2M $2M $2M $2M $1M $1M $181.0K
Retained Earnings 11-point trend, -5644.0% $-1.95B $-1.37B $-1000M $-846M $-196M $-574M $-225M $-292M $-125M $-57M $-34M
Treasury Stock 11-point trend, +60000.00 $60.0K $62.0K $62.0K $63.0K $63.0K $63.0K $63.0K $57.0K $0 $0 $0
AOCI 11-point trend, +60362.5% $5M $2M $2M $-16M $-5M $-83.0K $7.0K $-8.0K $14.0K $-26.0K $-8.0K
Stockholders' Equity 11-point trend, +6704.8% $1.92B $1.93B $1.88B $1.88B $2.40B $1.66B $939M $392M $188M $233M $-29M
Liabilities + Equity 11-point trend, +1320.9% $2.27B $2.24B $2.23B $2.24B $2.75B $1.83B $1.07B $489M $271M $345M $159M
Shares Outstanding 11-point trend, +1634.7% 95,894,341 85,741,981 80,044,378 78,512,450 76,990,066 73,914,844 60,783,799 51,852,862 40,592,248 39,719,434 5,528,079
Nakit Akışı 14
CRSP için Yıllık Nakit Akışı verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
D&A 11-point trend, +15237.8% $19M $19M $20M $24M $18M $9M $5M $4M $3M $925.0K $127.0K
Stock-based Comp 11-point trend, +1867.9% $72M $87M $81M $98M $102M $66M $44M $35M $19M $11M $4M
Deferred Tax 11-point trend, +1794.4% $915.0K $-484.0K $-424.0K $-1M $2M $409.0K $-34.0K $6.0K $180.0K $-137.0K $-54.0K
Other Non-cash 10-point trend, +428.3% $144M $118M $-207M $33M $39M $35M $-59M $30M $-24M $-44M ·
Operating Cash Flow 11-point trend, -680.6% $-345M $-143M $-260M $-496M $539M $-238M $57M $-96M $-70M $-53M $59M
CapEx 11-point trend, -20.8% $914.0K $2M $9M $37M $82M $18M $7M $3M $8M $3M $1M
Investing Cash Flow 10-point trend, -199.8% $-32M $-280M $375M $-259M $-1.04B $-541M $1M $-3M $-8M $32M ·
Stock Issued 10-point trend, +347.0% $398M $301M $33M $970.0K $213M $982M $415M $307M $0 $89M ·
Stock Repurchased · · · · · · · $57.0K · · ·
Net Stock Activity 8-point trend, +29.7% $398M $301M $33M $970.0K $213M $982M $415M $307M · · ·
Financing Cash Flow 10-point trend, +132.5% $426M $332M $63M $39M $251M $1.02B $431M $316M $3M $183M ·
Net Change in Cash 11-point trend, -68.2% $49M $-91M $177M $-716M $-246M $237M $489M $217M $-76M $162M $155M
Taxes Paid $3M · · · · · · · · · ·
Free Cash Flow 10-point trend, -493.1% $-346M $-145M $-270M $-533M $457M $-257M $50M $-99M $-78M $-58M ·
Kârlılık 7
CRSP için Yıllık Kârlılık verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Operating Margin 10-point trend, -1335.1% -18933.7% -1250.4% -60.0% -56190.4% 40.8% -49295.5% 16.1% -5087.8% -157.7% -1319.3% ·
Net Margin 10-point trend, -3591.9% -16569.8% -981.5% -41.4% -54271.7% 41.3% -48520.9% 23.1% -5281.1% -166.7% -448.8% ·
Pretax Margin 10-point trend, -3642.9% -16466.2% -971.9% -40.6% -54298.8% 41.5% -48408.3% 23.2% -5263.4% -162.5% -439.9% ·
EBITDA Margin 10-point trend, -1312.2% -18378.7% -1198.8% -54.6% -54172.7% 42.8% -48018.2% 17.8% -4975.2% -150.3% -1301.4% ·
ROA 10-point trend, -180.8% -25.8% -16.4% -6.9% -26.0% 16.5% -24.1% 8.6% -43.4% -22.2% -9.2% ·
ROE 10-point trend, -40.7% -32.0% -18.9% -8.5% -34.0% 15.4% -23.2% 8.7% -40.8% -32.5% -22.8% ·
ROIC 10-point trend, -16.5% -34.8% -24.4% -12.0% -35.9% 15.5% -21.3% 4.9% -40.7% -35.3% -29.9% ·
Likidite ve Solventlik 2
CRSP için Yıllık Likidite ve Solventlik verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Current Ratio 10-point trend, -8.5% 13.3 22.1 17.5 15.3 20.2 18.2 17.3 16.8 17.1 14.6 ·
Quick Ratio 10-point trend, -8.5% 13.2 22.0 17.4 15.0 19.8 17.9 16.5 16.5 16.7 14.5 ·
Verimlilik 2
CRSP için Yıllık Verimlilik verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Asset Turnover 10-point trend, -92.2% 0.0 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.1 0.0 ·
Receivables Turnover 10-point trend, -90.5% 0.3 0.3 3.7 7.9 4075.6 5.9 3097.2 2.3 14.2 3.0 ·
Hisse Başına 5
CRSP için Yıllık Hisse Başına verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Book Value / Share 10-point trend, +241.9% $20.04 $22.53 $23.52 $23.89 $31.17 $22.52 $15.46 $7.56 $4.63 $5.86 ·
Revenue / Share 7-point trend, -99.2% $0.04 $0.44 $4.69 $0.02 $11.38 $0.01 $5.09 · · · ·
Cash Flow / Share 7-point trend, -485.4% $-3.84 $-1.69 $-3.29 $-6.38 $6.70 $-3.61 $1.00 · · · ·
Cash / Share 10-point trend, -54.4% $3.62 $3.48 $4.87 $2.70 $11.99 $15.81 $15.53 $8.81 $5.91 $7.94 ·
EPS (TTM) 10-point trend, +8.2% $-6.47 $-4.34 $-1.94 $-8.36 $4.70 $-5.29 $1.17 $-3.44 $-1.71 $-7.05 ·
Büyüme Oranları 3
CRSP için Yıllık Büyüme Oranları verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Revenue YoY 5-point trend, -100.1% -90.6% -90.0% 30885.5% -99.9% 127154.9% · · · · · ·
Revenue CAGR 3Y 3-point trend, -93.9% 43.1% -65.6% 702.2% · · · · · · · ·
Revenue CAGR 5Y 37.3% · · · · · · · · · ·
Değerleme (TTM) 10
CRSP için Yıllık Değerleme (TTM) verileri
Metrik Eğilim 20252024202320222021202020192018201720162015
Revenue TTM 10-point trend, -32.0% $4M $37M $371M $1M $915M $719.0K $290M $3M $41M $5M ·
Net Income TTM 10-point trend, -2409.4% $-582M $-366M $-154M $-650M $378M $-349M $67M $-165M $-68M $-23M ·
Market Cap 10-point trend, +524.9% $5.03B $3.37B $5.01B $3.19B $5.83B $11.32B $3.70B $1.48B $953M $805M ·
P/E 10-point trend, -182.0% -8.1 -9.1 -32.3 -4.9 16.1 -28.9 52.1 -8.3 -13.7 -2.9 ·
P/S 10-point trend, +819.4% 1432.7 90.4 13.5 2664.0 6.4 15740.1 12.8 474.2 23.2 155.8 ·
P/B 10-point trend, -24.3% 2.6 1.7 2.7 1.7 2.4 6.8 3.9 3.8 5.1 3.5 ·
P / Tangible Book 6-point trend, -61.5% 2.6 1.7 2.7 1.7 2.4 6.8 · · · · ·
P / Cash Flow 10-point trend, -0.2% -14.6 -23.6 -19.2 -6.4 10.8 -47.5 65.3 -15.4 -13.6 -14.5 ·
P / FCF 10-point trend, -5.4% -14.5 -23.3 -18.6 -6.0 12.8 -44.1 74.1 -15.0 -12.2 -13.8 ·
Earnings Yield 10-point trend, +64.5% -12.3% -11.0% -3.1% -20.6% 6.2% -3.5% 1.9% -12.0% -7.3% -34.8% ·

Finansal Tablolar Gelir tablosu, bilanço, nakit akışı — yıllık, son 5 yıl

Gelir Tablosu
2025-12-312024-12-312023-12-312022-12-312021-12-31
Gelir $4M$37M$371M$1M$915M
Faaliyet Kâr Marjı % -18933.7%-1250.4%-60.0%-56190.4%40.8%
Net Gelir $-582M$-366M$-154M$-650M$378M
Seyreltilmiş Hisse Başı Kâr $-6.47$-4.34$-1.94$-8.36$4.70
Bilanço
2025-12-312024-12-312023-12-312022-12-312021-12-31
Cari Oran 13.322.117.515.320.2
Cari Oran 13.222.017.415.019.8
Nakit Akışı
2025-12-312024-12-312023-12-312022-12-312021-12-31
Serbest Nakit Akışı $-346M$-145M$-270M$-533M$457M

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Sizin için önemli olan metrikleri seçin — yukarıdaki Tam Temeller'deki herhangi bir satırın yanındaki ➕ düğmesine tıklayın.

Seçiminiz kaydedildi ve tüm hisse senetlerinde sizinle birlikte gelir.

Kurumsal Sahipler (13F) 573 dosya · $3.3B toplam · Tarih itibarıyla 30 Haziran 2026

Çeyreklik SEC Form 13F'lerinde bu hisse senedini tuttuklarını bildiren kurumlar. Yalnızca uzun pozisyonlar; tek bir başvuru sahibi, ayrı opsiyon bacakları için iki kez görünebilir. Büyük dengeleyici alım/satım bacakları genellikle piyasa yapımını veya korunmuş envanteri yansıtır, yönlü bir inancı değil.

Kurumsal faaliyet — Q2 2026 ve önceki çeyrek
Yeni pozisyonlar Çıkan pozisyonlar Artırıldı Azaldı Net hisse senedi değişimi
89 (0 önceki Ç'ye göre) 47 (-13 önceki Ç'ye göre) 148 (-24 önceki Ç'ye göre) 145 (+21 önceki Ç'ye göre) +5.4M

Q1 2026 ile karşılaştırıldı. SEC Form 13F başvuruları, çeyrek sonundan itibaren 45 gün içinde ve geç başvuranlar için kısa bir ek süre içinde tamamlanmalıdır — bu pencere içindeki çeyrekler, en son tam olarak raporlanan çifte tercih edilerek atlanır.

Kurum Değer Hisse senetleri % izlenen 13F'nin Tür
ARK Investment Management LLC $515.999.631 9.460.939 15,58% Hisse senetleri
Orbis Allan Gray Ltd $296.334.582 5.433.344 8,95% Hisse senetleri
Capital World Investors $259.039.094 4.749.525 7,82% Hisse senetleri
STATE STREET CORP $235.703.664 4.321.666 7,12% Hisse senetleri
GSK plc $175.652.997 3.220.627 5,30% Hisse senetleri
GEODE CAPITAL MANAGEMENT, LLC $117.453.717 2.153.015 3,55% Hisse senetleri
SR One Capital Management, LP $111.194.134 2.038.763 3,36% Hisse senetleri
TWO SIGMA INVESTMENTS, LP $108.459.389 1.988.621 3,27% Hisse senetleri
Sumitomo Mitsui Trust Group, Inc. $93.848.832 1.720.734 2,83% Hisse senetleri
Amova Asset Management Americas, Inc. $93.762.487 1.720.097 2,83% Hisse senetleri
EcoR1 Capital, LLC $75.771.113 1.389.276 2,29% Hisse senetleri
Capital International Investors $69.178.918 1.268.407 2,09% Hisse senetleri
VANGUARD CAPITAL MANAGEMENT LLC $64.457.935 1.181.847 1,95% Hisse senetleri
NEA Management Company, LLC $57.734.408 1.058.570 1,74% Hisse senetleri
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $57.694.430 1.057.837 1,74% Hisse senetleri
FMR LLC $53.577.751 982.357 1,62% Hisse senetleri
D. E. Shaw & Co., Inc. $48.748.506 893.812 1,47% Hisse senetleri
VANGUARD PORTFOLIO MANAGEMENT LLC $35.380.807 648.713 1,07% Hisse senetleri
UBS Group AG $32.419.612 594.419 0,98% Hisse senetleri
VANGUARD FIDUCIARY TRUST CO $31.089.982 570.040 0,94% Hisse senetleri
VANGUARD GROUP INC $27.714.225 528.494 0,84% Hisse senetleri
CITADEL ADVISORS LLC $25.404.514 465.796 0,77% Hisse senetleri
BANK OF AMERICA CORP /DE/ $23.509.740 431.055 0,71% Hisse senetleri
SUSQUEHANNA INTERNATIONAL GROUP, LLP $23.298.288 427.178 0,70% Hisse senetleri
MILLENNIUM MANAGEMENT LLC $20.836.025 382.032 0,63% Hisse senetleri
IQ EQ FUND MANAGEMENT (IRELAND) Ltd $20.833.789 381.991 0,63% Hisse senetleri
SUSQUEHANNA INTERNATIONAL GROUP, LLP $18.456.336 338.400 0,56% Satım opsiyonu
SUSQUEHANNA INTERNATIONAL GROUP, LLP $17.763.678 325.700 0,54% Alım opsiyonu
Logos Global Management LP $16.362.000 300.000 0,49% Hisse senetleri
CITADEL ADVISORS LLC $15.822.054 290.100 0,48% Satım opsiyonu
Squarepoint Ops LLC $15.641.472 286.789 0,47% Hisse senetleri
NORGES BANK $14.767.032 270.756 0,45% Hisse senetleri
CITADEL ADVISORS LLC $13.973.148 256.200 0,42% Alım opsiyonu
GOLDMAN SACHS GROUP INC $12.748.193 233.740 0,38% Hisse senetleri
JANE STREET GROUP, LLC $12.566.016 230.400 0,38% Alım opsiyonu
PEAK6 LLC $11.633.382 213.300 0,35% Satım opsiyonu
Swiss National Bank $9.228.168 169.200 0,28% Hisse senetleri
Susquehanna Portfolio Strategies, LLC $8.945.978 164.026 0,27% Hisse senetleri
TWO SIGMA ADVISERS, LP $8.516.256 162.400 0,26% Hisse senetleri
LPL Financial LLC $8.376.280 153.581 0,25% Hisse senetleri
Bank of New York Mellon Corp $8.337.366 152.867 0,25% Hisse senetleri
DIMENSIONAL FUND ADVISORS LP $8.301.261 152.205 0,25% Hisse senetleri
Versant Venture Management, LLC $8.117.243 148.831 0,25% Hisse senetleri
Pictet Asset Management Holding SA $7.989.776 142.213 0,24% Hisse senetleri
Life Cycle Investment Partners Ltd $7.836.962 143.692 0,24% Hisse senetleri
TD Asset Management Inc $7.777.513 142.602 0,23% Hisse senetleri
AMERICAN CENTURY COMPANIES INC $7.606.257 139.462 0,23% Hisse senetleri
RAYMOND JAMES FINANCIAL INC $7.230.750 132.577 0,22% Hisse senetleri
RHUMBLINE ADVISERS $6.627.197 121.511 0,20% Hisse senetleri
SFE Investment Counsel $6.229.434 16.700 0,19% Satım opsiyonu
Private Advisor Group, LLC $6.060.980 111.129 0,18% Hisse senetleri
EverSource Wealth Advisors, LLC $6.032.669 110.610 0,18% Hisse senetleri
CONGRESS ASSET MANAGEMENT CO $5.969.567 109.453 0,18% Hisse senetleri
BlackRock, Inc. $5.937.061 108.857 0,18% Hisse senetleri
D. E. Shaw & Co., Inc. $5.901.228 108.200 0,18% Alım opsiyonu
Campbell & CO Investment Adviser LLC $5.864.632 107.529 0,18% Hisse senetleri
JANE STREET GROUP, LLC $5.852.142 107.300 0,18% Satım opsiyonu
California Public Employees Retirement System $5.599.567 102.669 0,17% Hisse senetleri
CAPITAL INTERNATIONAL SARL $5.521.521 101.238 0,17% Hisse senetleri
Affinity Asset Advisors, LLC $5.454.000 100.000 0,16% Hisse senetleri
ALLIANCEBERNSTEIN L.P. $5.439.011 114.337 0,16% Hisse senetleri
CLOUGH CAPITAL PARTNERS L P $5.363.300 98.337 0,16% Hisse senetleri
Zurcher Kantonalbank (Zurich Cantonalbank) $5.172.465 94.838 0,16% Hisse senetleri
Slow Capital, Inc. $5.066.439 92.894 0,15% Hisse senetleri
CAPITAL FUND MANAGEMENT S.A. $4.867.258 89.242 0,15% Hisse senetleri
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $4.815.606 101.232 0,15% Hisse senetleri
VANGUARD ASSET MANAGEMENT, Ltd $4.720.437 86.550 0,14% Hisse senetleri
GROUP ONE TRADING LLC $4.638.082 85.040 0,14% Hisse senetleri
HIMENSION CAPITAL (SINGAPORE) PTE. LTD. $4.575.742 83.897 0,14% Hisse senetleri
STATE OF MICHIGAN RETIREMENT SYSTEM $4.502.113 82.547 0,14% Hisse senetleri
Concurrent Investment Advisors, LLC $4.497.728 82.467 0,14% Hisse senetleri
WELLS FARGO & COMPANY/MN $4.309.151 79.009 0,13% Hisse senetleri
Fisher Asset Management, LLC $4.251.957 77.960 0,13% Hisse senetleri
Trexquant Investment LP $4.225.268 77.471 0,13% Hisse senetleri
COMMONWEALTH EQUITY SERVICES, LLC $4.194.122 76.900 0,13% Hisse senetleri
JONES FINANCIAL COMPANIES LLLP $4.055.652 73.847 0,12% Hisse senetleri
Man Group plc $3.992.001 73.194 0,12% Hisse senetleri
PEAK6 LLC $3.834.162 70.300 0,12% Alım opsiyonu
ENVESTNET ASSET MANAGEMENT INC $3.822.196 70.081 0,12% Hisse senetleri
ALGERT GLOBAL LLC $3.593.095 65.880 0,11% Hisse senetleri
Walleye Trading LLC $3.528.738 64.700 0,11% Satım opsiyonu
MILLENNIUM MANAGEMENT LLC $3.146.958 57.700 0,10% Alım opsiyonu
CAPITAL INTERNATIONAL LTD /CA/ $3.057.840 56.066 0,09% Hisse senetleri
NOMURA HOLDINGS INC $3.055.713 56.027 0,09% Hisse senetleri
Rafferty Asset Management, LLC $3.045.132 55.833 0,09% Hisse senetleri
Green Alpha Advisors, LLC $3.043.550 55.804 0,09% Hisse senetleri
Walleye Trading LLC $3.005.154 55.100 0,09% Alım opsiyonu
Caption Management, LLC $2.999.700 55.000 0,09% Alım opsiyonu
MetLife Investment Management, LLC $2.958.413 54.243 0,09% Hisse senetleri
BENJAMIN EDWARDS INC $2.956.845 54.216 0,09% Hisse senetleri
Quantinno Capital Management LP $2.869.349 52.610 0,09% Hisse senetleri
Cetera Investment Advisers $2.856.133 52.368 0,09% Hisse senetleri
STATE OF WISCONSIN INVESTMENT BOARD $2.788.521 51.128 0,08% Hisse senetleri
CITIGROUP INC $2.781.540 51.000 0,08% Alım opsiyonu
CITIGROUP INC $2.781.540 51.000 0,08% Satım opsiyonu
WOLVERINE ASSET MANAGEMENT LLC $2.727.000 50.000 0,08% Satım opsiyonu
OSAIC HOLDINGS, INC. $2.693.150 49.381 0,08% Hisse senetleri
Privium Fund Management B.V. $2.452.882 44.974 0,07% Hisse senetleri
CANADA PENSION PLAN INVESTMENT BOARD $2.394.306 43.900 0,07% Hisse senetleri
TUDOR INVESTMENT CORP ET AL $2.318.604 42.512 0,07% Hisse senetleri

Şirket yöneticileri 32 içeriden öğrenenler · 12 yöneticiler · 16 yönetim kurulu üyeleri

İçeriden Öğrenen Rol Son işlem Sahip olunan hisse senetleri Alımlar 12ay Satışlar 12ay Net 12ay
Samarth Kulkarni Chief Executive Officer 20 Mart 2026 M 255.501 0 9 $-10.756.932
Brendan Smith Chief Financial Officer 18 Şubat 2023 M 5.072 0 0 $0
Michael John Tomsicek Chief Financial Officer 11 Mart 2021 M 1.891 0 0 $0
Julianne Bruno Chief Operating Officer 20 Mart 2025 M 10.544 0 0 $0
Lawrence Otto Klein CBO & COO 16 Ağustos 2022 A 26.797 0 0 $0
Naimish Patel Chief Medical Officer 29 Mayıs 2026 A 19.357 1 2 $-312.892
James R. Kasinger General Counsel and Secretary 29 Mayıs 2026 A 94.308 0 5 $-645.902
Phuong Khanh Morrow Chief Medical Officer 13 Ekim 2023 A 4.411 0 0 $0
Tony W Ho Executive VP, Head of R&D 03 Aralık 2021 M 52.364 0 0 $0
Tyler Dylan-Hyde Chief Legal Officer 16 Ocak 2018 M 25.204 0 0 $0
Kala Subramanian Senior Vice President, Strategic Development and Operations 15 Haziran 2017 A 0 0 $0
Sven Ante Lundberg Chief Scientific Officer 24 Ekim 2016 C 505.617 0 0 $0
Christian Rommel Yönetim kurulu üyesi 05 Haziran 2026 A 0 0 $0
Harold Edward Fleming Yönetim kurulu üyesi 05 Haziran 2026 A 0 0 $0
Douglas A Treco Yönetim kurulu üyesi 05 Haziran 2026 A 0 0 $0
Briggs Morrison Yönetim kurulu üyesi 05 Haziran 2026 A 0 0 $0
Katherine A High Yönetim kurulu üyesi 05 Haziran 2026 A 0 0 $0
Ali Behbahani Yönetim kurulu üyesi 05 Haziran 2026 A 14 0 0 $0
John Greene Yönetim kurulu üyesi 05 Haziran 2026 A 7.000 0 0 $0
Simeon George Yönetim kurulu üyesi 05 Haziran 2026 A 1.730.179 0 0 $0
Maria Fardis Yönetim kurulu üyesi 05 Haziran 2026 A 0 0 $0
Sandesh Mahatme Yönetim kurulu üyesi 05 Haziran 2026 A 0 0 $0
Bradley J Bolzon PhD Yönetim kurulu üyesi 09 Haziran 2022 A 148.831 0 0 $0
Pablo J Cagnoni Yönetim kurulu üyesi 19 Kasım 2019 M 0 0 0 $0
Kurt Von Emster Yönetim kurulu üyesi 18 Aralık 2018 S 1.171.268 0 0 $0
Thomas Woiwode Yönetim kurulu üyesi 15 Haziran 2018 A 640.014 0 0 $0
Anthony N Coles Yönetim kurulu üyesi 31 Mayıs 2017 A 70.000 0 0 $0
CELGENE CORP /DE/ 10% sahip 04 Aralık 2017 S 3.722.534 0 0 $0
Hadley Harbor Master Investors (Cayman) L.P. 10% sahip 24 Ekim 2016 C 744.380 0 0 $0
GSK plc 10% sahip 24 Ekim 2016 C 3.220.627 0 0 $0
Raju Prasad 07 Ağustos 2026 G 14.815 0 10 $-5.100.841
Rodger Novak 30 Haziran 2021 S 573.007 0 0 $0

SEC Form 3/4/5 başvurularından yöneticiler; net = yalnızca açık piyasa Alış/Satış

Aktivistler ve %5+ sahipler 6 pozisyon

SEC Çizelge 13D dosyalayan yatırımcılar — ihraççı üzerinde nüfuz etme niyetiyle %5'in üzerinde faydalı sahiplik (aktivist hisseler, yönetim kurulu kampanyaları, M&A). Her satır, o başvuru sahibinin pozisyonunun bilinen en son durumunu gösterir.

Başvuru sahibi Dosyalandı Hisse Durum Amaç Başvuru
Versant Venture Capital IV, L.P., Versant Side Fund IV, L.P., Versant Ventures IV, LLC, Versant Venture Capital V, L.P., Versant Affiliates Fund V, L.P., Versant Ophthalmic Affiliates Fund I, L.P., Versant Ventures V, LLC, Versant Venture Capital V (Canada) LP, Versant Ventures V GP-GP (Canada), Inc., Versant Ventures V (Canada), L.P., Versant Venture Management, LLC ×5 başvurular 16 Şubat 2021 İlk başvuru SEC
GlaxoSmithKline plc ×5 başvurular 10 Temmuz 2020 İlk başvuru SEC
Bayer Global Investments B.V., Bayer AG ×4 başvurular 04 Şubat 2020 İlk başvuru SEC
Vertex Pharmaceuticals Incorporated (“Vertex US”), Vertex Pharmaceuticals (Europe) Limited (“Vertex Europe”) ×4 başvurular 07 Haziran 2019 İlk başvuru SEC
CELGENE ALPINE INVESTMENT CO. III, LLC, CELGENE CORPORATION ×4 başvurular 08 Şubat 2018 İlk başvuru SEC
Abingworth LLP 98-051-8585, Abingworth Bioventures VI, LP ×3 başvurular 16 Ocak 2018 İlk başvuru SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF sahipliği 32 ETF'ler tarafından tutuluyor

Ağırlık yalnızca doğrudan öz sermaye varlıklarını (N-PORT) yansıtır; kaldıraçlı veya türev tabanlı fonlar gösterilmeyen ek swap pozisyonlarına sahip olabilir.

Fon Ağırlık Birimler Tarih itibarıyla Kaynak
GNOM · Global X Funds 3,85% 38.191 NS 31 Mayıs 2026 N-PORT
IDNA · iShares Trust 1,63% 62.247 SH 08 Ağustos 2026 Günlük
LABU · Direxion Shares ETF Trust 0,98% 97.235 NS 30 Nisan 2026 N-PORT
IBB · iShares Trust 0,36% 658.537 SH 08 Ağustos 2026 Günlük
IBBQ · Invesco Exchange-Traded Fund Trust … 0,35% 5.248 SH 08 Ağustos 2026 Günlük
VTWV · VANGUARD SCOTTSDALE FUNDS 0,28% 70.696 SH 08 Ağustos 2026 Günlük
IWN · iShares Trust 0,27% 752.223 SH 08 Ağustos 2026 Günlük
AVSC · AMERICAN CENTURY ETF TRUST 0,21% 104.016 NS 31 Mayıs 2026 N-PORT
ISCV · iShares Trust 0,15% 20.568 SH 08 Ağustos 2026 Günlük
IWM · iShares Trust 0,15% 2.353.025 SH 08 Ağustos 2026 Günlük
VTWO · VANGUARD SCOTTSDALE FUNDS 0,15% 536.446 SH 08 Ağustos 2026 Günlük
RSSL · Global X Funds 0,15% 39.589 NS 30 Nisan 2026 N-PORT
PDN · Invesco Exchange-Traded Fund Trust … 0,10% 6.636 SH 08 Ağustos 2026 Günlük
ISCB · iShares Trust 0,07% 4.136 SH 08 Ağustos 2026 Günlük
SMLF · iShares Trust 0,07% 57.970 SH 08 Ağustos 2026 Günlük
VXF · VANGUARD INDEX FUNDS 0,06% 1.106.455 SH 08 Ağustos 2026 Günlük
ESML · iShares Trust 0,06% 33.283 SH 08 Ağustos 2026 Günlük
AVIE · AMERICAN CENTURY ETF TRUST 0,06% 108 NS 31 Mayıs 2026 N-PORT
WSML · iShares Trust 0,04% 5.486 SH 08 Ağustos 2026 Günlük
VTWG · VANGUARD SCOTTSDALE FUNDS 0,04% 13.170 SH 08 Ağustos 2026 Günlük
IWO · iShares Trust 0,04% 109.974 SH 08 Ağustos 2026 Günlük
OMFS · Invesco Exchange-Traded Self-Indexe… 0,03% 1.736 SH 08 Ağustos 2026 Günlük
XT · iShares Trust 0,03% 21.837 SH 08 Ağustos 2026 Günlük
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,03% 3.509 NS 31 Mayıs 2026 N-PORT
VTHR · VANGUARD SCOTTSDALE FUNDS 0,01% 7.774 SH 08 Ağustos 2026 Günlük
ESGV · VANGUARD WORLD FUND 0,01% 20.627 SH 08 Ağustos 2026 Günlük
IYY · iShares Trust 0,01% 4.231 SH 08 Ağustos 2026 Günlük
ITOT · iShares Trust 0,01% 128.511 SH 08 Ağustos 2026 Günlük
AVUS · AMERICAN CENTURY ETF TRUST 0,01% 15.609 NS 31 Mayıs 2026 N-PORT
IWV · iShares Trust 0,01% 25.457 SH 08 Ağustos 2026 Günlük
AVSU · AMERICAN CENTURY ETF TRUST 0,00% 289 NS 31 Mayıs 2026 N-PORT
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0,00% 75.392 SH 08 Ağustos 2026 Günlük