IRON — الملاك المؤسسيون (13F)
المؤسسات التي تبلغ عن حيازتها لهذا السهم في نموذج SEC 13F ربع السنوي الخاص بها. المراكز الطويلة فقط؛ قد يظهر مقدم واحد مرتين لأرجل خيارات منفصلة. الأرجل الكبيرة المتعاكسة من خيارات البيع/الشراء تعكس عادةً صناعة السوق أو المخزون المتحوط، وليس القناعة الاتجاهية.
| مؤسسة | القيمة | الأسهم | % من 13F المتتبعة | النوع |
|---|---|---|---|---|
| FMR LLC | $357981753 | 4894473 | 11,37% | الأسهم |
| BlackRock, Inc. | $180502133 | 2467899 | 5,73% | الأسهم |
| RA CAPITAL MANAGEMENT, L.P. | $179209164 | 2450221 | 5,69% | الأسهم |
| VANGUARD GROUP INC | $140371470 | 1767680 | 4,46% | الأسهم |
| JPMORGAN CHASE & CO | $139868053 | 1875795 | 4,44% | الأسهم |
| WELLINGTON MANAGEMENT GROUP LLP | $127362413 | 1741351 | 4,05% | الأسهم |
| STATE STREET CORP | $120595865 | 1648836 | 3,83% | الأسهم |
| Vestal Point Capital, LP | $113367000 | 1550000 | 3,60% | الأسهم |
| Atlas Venture Life Science Advisors, LLC | $110724818 | 1513875 | 3,52% | الأسهم |
| VANGUARD CAPITAL MANAGEMENT LLC | $100130635 | 1369027 | 3,18% | الأسهم |
| Frazier Life Sciences Management, L.P. | $99093875 | 1354852 | 3,15% | الأسهم |
| TCG Crossover Management, LLC | $98143787 | 1341862 | 3,12% | الأسهم |
| BVF INC/IL | $84375182 | 1153612 | 2,68% | الأسهم |
| Woodline Partners LP | $70088672 | 958281 | 2,23% | الأسهم |
| Siren, L.L.C. | $64977649 | 888401 | 2,06% | الأسهم |
| Logos Global Management LP | $63997500 | 875000 | 2,03% | الأسهم |
| Opaleye Management Inc. | $62534700 | 855000 | 1,99% | الأسهم |
| GEODE CAPITAL MANAGEMENT, LLC | $57772342 | 789724 | 1,84% | الأسهم |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $48052980 | 657000 | 1,53% | الأسهم |
| DIMENSIONAL FUND ADVISORS LP | $41622451 | 569018 | 1,32% | الأسهم |
| Bellevue Group AG | $40958400 | 560000 | 1,30% | الأسهم |
| Saturn V Capital Management LP | $38378752 | 524730 | 1,22% | الأسهم |
| ARMISTICE CAPITAL, LLC | $33644400 | 460000 | 1,07% | الأسهم |
| JENNISON ASSOCIATES LLC | $32146492 | 439520 | 1,02% | الأسهم |
| Aberdeen Group plc | $32048046 | 438174 | 1,02% | الأسهم |
| Palo Alto Investors LP | $30473488 | 416646 | 0,97% | الأسهم |
| EVENTIDE ASSET MANAGEMENT, LLC | $28938480 | 395651 | 0,92% | الأسهم |
| Pictet Asset Management Holding SA | $28186328 | 385375 | 0,90% | الأسهم |
| Assenagon Asset Management S.A. | $28097316 | 384158 | 0,89% | الأسهم |
| LOOMIS SAYLES & CO L P | $27929533 | 381864 | 0,89% | الأسهم |
| Foresite Capital Management V, LLC | $27359407 | 374069 | 0,87% | الأسهم |
| ORBIMED ADVISORS LLC | $26150110 | 357535 | 0,83% | الأسهم |
| BAKER BROS. ADVISORS LP | $25573913 | 349657 | 0,81% | الأسهم |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20620872 | 281937 | 0,66% | الأسهم |
| Octagon Capital Advisors LP | $19747800 | 270000 | 0,63% | الأسهم |
| NORTHERN TRUST CORP | $19381368 | 264990 | 0,62% | الأسهم |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $18824919 | 257382 | 0,60% | الأسهم |
| Checkpoint Capital L.P. | $17562743 | 240125 | 0,56% | الأسهم |
| VANGUARD FIDUCIARY TRUST CO | $16470982 | 225198 | 0,52% | الأسهم |
| CITADEL ADVISORS LLC | $15308787 | 209308 | 0,49% | الأسهم |
| Bank of New York Mellon Corp | $14973763 | 204727 | 0,48% | الأسهم |
| BNP PARIBAS FINANCIAL MARKETS | $13508592 | 184695 | 0,43% | الأسهم |
| Catalio Capital Management, LP | $11657346 | 159384 | 0,37% | الأسهم |
| Caption Management, LLC | $10971000 | 150000 | 0,35% | عقد خيار الشراء |
| Sofinnova Investments, Inc. | $10695920 | 146239 | 0,34% | الأسهم |
| Bain Capital Life Sciences Investors, LLC | $10329855 | 141234 | 0,33% | الأسهم |
| TWO SIGMA INVESTMENTS, LP | $10001895 | 136750 | 0,32% | الأسهم |
| BANK OF AMERICA CORP /DE/ | $9882018 | 135111 | 0,31% | الأسهم |
| Alyeska Investment Group, L.P. | $9142500 | 125000 | 0,29% | الأسهم |
| Ensign Peak Advisors, Inc | $8931199 | 122111 | 0,28% | الأسهم |
| UBS Group AG | $8116419 | 110971 | 0,26% | الأسهم |
| Trexquant Investment LP | $7877105 | 107699 | 0,25% | الأسهم |
| KENNEDY CAPITAL MANAGEMENT LLC | $7809085 | 106769 | 0,25% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $7770979 | 106248 | 0,25% | الأسهم |
| GOLDMAN SACHS GROUP INC | $7122593 | 97383 | 0,23% | الأسهم |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $7090307 | 110890 | 0,23% | الأسهم |
| MORGAN STANLEY | $6699315 | 91595 | 0,21% | الأسهم |
| SILVERARC CAPITAL MANAGEMENT, LLC | $6055992 | 82800 | 0,19% | الأسهم |
| RAYMOND JAMES FINANCIAL INC | $5703384 | 77980 | 0,18% | الأسهم |
| Squarepoint Ops LLC | $5549278 | 75872 | 0,18% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5383104 | 73600 | 0,17% | عقد خيار الشراء |
| DNB Asset Management AS | $5348509 | 73127 | 0,17% | الأسهم |
| Casdin Capital, LLC | $4754100 | 65000 | 0,15% | الأسهم |
| SPHERA FUNDS MANAGEMENT LTD. | $4647169 | 63538 | 0,15% | الأسهم |
| Nuveen, LLC | $4414511 | 60357 | 0,14% | الأسهم |
| PEAK6 LLC | $4388400 | 60000 | 0,14% | عقد خيار الشراء |
| KVP Capital Advisors, LP | $4260405 | 58250 | 0,14% | الأسهم |
| MOORE CAPITAL MANAGEMENT, LP | $4227199 | 57796 | 0,13% | الأسهم |
| XTX Topco Ltd | $4147769 | 56710 | 0,13% | الأسهم |
| NEXTBio Capital Management LP | $3851187 | 52655 | 0,12% | الأسهم |
| ALGERT GLOBAL LLC | $3792309 | 51850 | 0,12% | الأسهم |
| ExodusPoint Capital Management, LP | $3775706 | 51623 | 0,12% | الأسهم |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $3725000 | 50000 | 0,12% | الأسهم |
| Burkehill Global Management, LP | $3657000 | 50000 | 0,12% | الأسهم |
| Brevan Howard Capital Management LP | $3656707 | 49996 | 0,12% | الأسهم |
| Swiss National Bank | $3642372 | 49800 | 0,12% | الأسهم |
| AMERIPRISE FINANCIAL INC | $3355224 | 45874 | 0,11% | الأسهم |
| Atle Fund Management AB | $3194901 | 43682 | 0,10% | الأسهم |
| Quadrature Capital Ltd | $3102526 | 42419 | 0,10% | الأسهم |
| Invesco Ltd. | $3076049 | 42057 | 0,10% | الأسهم |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2878790 | 39360 | 0,09% | الأسهم |
| ALPS ADVISORS INC | $2820644 | 38565 | 0,09% | الأسهم |
| CITIGROUP INC | $2802506 | 38317 | 0,09% | الأسهم |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $2798483 | 38262 | 0,09% | الأسهم |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $2679411 | 36634 | 0,09% | الأسهم |
| RHUMBLINE ADVISERS | $2621620 | 35844 | 0,08% | الأسهم |
| LAZARD ASSET MANAGEMENT LLC | $2562387 | 35034 | 0,08% | الأسهم |
| SEVEN GRAND MANAGERS, LLC | $2559900 | 35000 | 0,08% | الأسهم |
| MARSHALL WACE, LLP | $2515577 | 34394 | 0,08% | الأسهم |
| Jump Financial, LLC | $2380634 | 32549 | 0,08% | الأسهم |
| BANK OF MONTREAL /CAN/ | $2363007 | 32308 | 0,08% | الأسهم |
| DEUTSCHE BANK AG\ | $2241229 | 30643 | 0,07% | الأسهم |
| ALLIANCEBERNSTEIN L.P. | $2216800 | 34670 | 0,07% | الأسهم |
| RTW INVESTMENTS, LP | $2194200 | 30000 | 0,07% | الأسهم |
| Squadron Capital Management LLC | $2194200 | 30000 | 0,07% | عقد خيار الشراء |
| VICTORY CAPITAL MANAGEMENT INC | $2129618 | 29117 | 0,07% | الأسهم |
| WELLS FARGO & COMPANY/MN | $2115464 | 28924 | 0,07% | الأسهم |
| TUDOR INVESTMENT CORP ET AL | $2096412 | 28663 | 0,07% | الأسهم |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2031171 | 27771 | 0,06% | الأسهم |
| Y-Intercept (Hong Kong) Ltd | $1966588 | 26888 | 0,06% | الأسهم |
| Rafferty Asset Management, LLC | $1943037 | 26566 | 0,06% | الأسهم |
| Campbell & CO Investment Adviser LLC | $1870044 | 25568 | 0,06% | الأسهم |
| PNC Financial Services Group, Inc. | $1633435 | 22333 | 0,05% | الأسهم |
| TD Asset Management Inc | $1579824 | 21600 | 0,05% | الأسهم |
| Engineers Gate Manager LP | $1430033 | 19552 | 0,05% | الأسهم |
| BARCLAYS PLC | $1368450 | 18710 | 0,04% | الأسهم |
| Legal & General Group Plc | $1350019 | 18458 | 0,04% | الأسهم |
| DLD Asset Management, LP | $1330238 | 18200 | 0,04% | عقد خيار البيع |
| CITADEL ADVISORS LLC | $1258008 | 17200 | 0,04% | عقد خيار البيع |
| MetLife Investment Management, LLC | $1213246 | 16588 | 0,04% | الأسهم |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1182775 | 16114 | 0,04% | الأسهم |
| VANGUARD ASSET MANAGEMENT, Ltd | $1178359 | 16111 | 0,04% | الأسهم |
| JANE STREET GROUP, LLC | $1171045 | 16011 | 0,04% | الأسهم |
| CITADEL ADVISORS LLC | $1155612 | 15800 | 0,04% | عقد خيار الشراء |
| STATE OF WISCONSIN INVESTMENT BOARD | $1128477 | 15429 | 0,04% | الأسهم |
| Man Group plc | $1091615 | 14925 | 0,03% | الأسهم |
| HighVista Strategies LLC | $1039978 | 14219 | 0,03% | الأسهم |
| PROFUND ADVISORS LLC | $988048 | 13509 | 0,03% | الأسهم |
| Ikarian Capital, LLC | $972762 | 13300 | 0,03% | عقد خيار الشراء |
| Ikarian Capital, LLC | $972762 | 13300 | 0,03% | عقد خيار البيع |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $948699 | 12971 | 0,03% | الأسهم |
| Qube Research & Technologies Ltd | $933120 | 12758 | 0,03% | الأسهم |
| SEI INVESTMENTS CO | $925008 | 12647 | 0,03% | الأسهم |
| MARTINGALE ASSET MANAGEMENT L P | $878339 | 12009 | 0,03% | الأسهم |
| Vanguard Global Advisers, LLC | $848205 | 11597 | 0,03% | الأسهم |
| JANUS HENDERSON GROUP PLC | $739462 | 11555 | 0,02% | الأسهم |
| NEW YORK STATE COMMON RETIREMENT FUND | $736959 | 10076 | 0,02% | الأسهم |
| AQR CAPITAL MANAGEMENT LLC | $721745 | 9868 | 0,02% | الأسهم |
| JANE STREET GROUP, LLC | $665574 | 9100 | 0,02% | عقد خيار الشراء |
| Entropy Technologies, LP | $614961 | 8408 | 0,02% | الأسهم |
| Police & Firemen's Retirement System of New Jersey | $610353 | 8345 | 0,02% | الأسهم |
| China Universal Asset Management Co., Ltd. | $602600 | 8239 | 0,02% | الأسهم |
| Lion Point Capital, LP | $592434 | 8100 | 0,02% | الأسهم |
| Russell Investments Group, Ltd. | $591190 | 8083 | 0,02% | الأسهم |
| State of New Jersey Common Pension Fund D | $586583 | 8020 | 0,02% | الأسهم |
| PSP Research LLC | $585120 | 8000 | 0,02% | الأسهم |
| Cubist Systematic Strategies, LLC | $575848 | 8714 | 0,02% | الأسهم |
| Quantinno Capital Management LP | $533703 | 7297 | 0,02% | الأسهم |
| JANE STREET GROUP, LLC | $526608 | 7200 | 0,02% | عقد خيار البيع |
| ARIZONA STATE RETIREMENT SYSTEM | $500570 | 6844 | 0,02% | الأسهم |
| EntryPoint Capital, LLC | $465975 | 6371 | 0,01% | الأسهم |
| SummitTX Capital, L.P. | $461440 | 6309 | 0,01% | الأسهم |
| Creative Planning | $457418 | 6254 | 0,01% | الأسهم |
| INTECH INVESTMENT MANAGEMENT LLC | $442790 | 6054 | 0,01% | الأسهم |
| AXQ CAPITAL, LP | $441400 | 6035 | 0,01% | الأسهم |
| D. E. Shaw & Co., Inc. | $440815 | 6027 | 0,01% | الأسهم |
| Vanguard Investments Australia, Ltd. | $435841 | 5959 | 0,01% | الأسهم |
| Susquehanna Portfolio Strategies, LLC | $424797 | 5808 | 0,01% | الأسهم |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $412510 | 5640 | 0,01% | الأسهم |
| VOYA INVESTMENT MANAGEMENT LLC | $397150 | 5430 | 0,01% | الأسهم |
| KLP KAPITALFORVALTNING AS | $380328 | 5200 | 0,01% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $365700 | 5000 | 0,01% | عقد خيار البيع |
| ProShare Advisors LLC | $362701 | 4959 | 0,01% | الأسهم |
| Virtus Investment Advisers, LLC | $351950 | 4812 | 0,01% | الأسهم |
| JONES FINANCIAL COMPANIES LLLP | $345184 | 4616 | 0,01% | الأسهم |
| PRUDENTIAL FINANCIAL INC | $338638 | 4630 | 0,01% | الأسهم |
| Eleva Capital SAS | $327053 | 5115 | 0,01% | الأسهم |
| Fiduciary Trust Co | $296290 | 4051 | 0,01% | الأسهم |
| AlphaCentric Advisors LLC | $294754 | 4030 | 0,01% | الأسهم |
| BOOTHBAY FUND MANAGEMENT, LLC | $292560 | 4000 | 0,01% | عقد خيار الشراء |
| BOOTHBAY FUND MANAGEMENT, LLC | $292560 | 4000 | 0,01% | عقد خيار البيع |
| E Fund Management Co., Ltd. | $273982 | 3746 | 0,01% | الأسهم |
| Bryce Point Capital, LLC | $258505 | 3912 | 0,01% | الأسهم |
| CAPSTONE INVESTMENT ADVISORS, LLC | $245385 | 3355 | 0,01% | الأسهم |
| Jain Global LLC | $228928 | 3130 | 0,01% | الأسهم |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $225417 | 3082 | 0,01% | الأسهم |
| DLD Asset Management, LP | $219420 | 3000 | 0,01% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $213130 | 2914 | 0,01% | الأسهم |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $211741 | 2895 | 0,01% | الأسهم |
| STRS OHIO | $197478 | 2700 | 0,01% | الأسهم |
| Ameritas Investment Partners, Inc. | $187824 | 2568 | 0,01% | الأسهم |
| Quantbot Technologies LP | $152863 | 2090 | 0,00% | الأسهم |
| PRICE T ROWE ASSOCIATES INC /MD/ | $137168 | 1875399 | 0,00% | الأسهم |
| Mirae Asset Global Investments Co., Ltd. | $124923 | 1708 | 0,00% | الأسهم |
| US BANCORP \DE\ | $89889 | 1229 | 0,00% | الأسهم |
| ROYAL BANK OF CANADA | $73000 | 989 | 0,00% | الأسهم |
| Foresite Capital Management VI LLC | $70946 | 970 | 0,00% | الأسهم |
| Tower Research Capital LLC (TRC) | $68678 | 939 | 0,00% | الأسهم |
| CWM, LLC | $66178 | 1035 | 0,00% | الأسهم |
| GF FUND MANAGEMENT CO. LTD. | $59170 | 809 | 0,00% | الأسهم |
| Allworth Financial LP | $46298 | 633 | 0,00% | الأسهم |
| NISA INVESTMENT ADVISORS, LLC | $41397 | 566 | 0,00% | الأسهم |
| Steward Partners Investment Advisory, LLC | $38618 | 528 | 0,00% | الأسهم |
| Bayforest Capital Ltd | $32986 | 451 | 0,00% | الأسهم |
| AlphaQuest LLC | $29064 | 366 | 0,00% | الأسهم |
| State of Wyoming | $25306 | 346 | 0,00% | الأسهم |
| GAMMA Investing LLC | $21357 | 292 | 0,00% | الأسهم |
| Kemnay Advisory Services Inc. | $19675 | 269 | 0,00% | الأسهم |
| OSAIC HOLDINGS, INC. | $19602 | 268 | 0,00% | الأسهم |
| TORONTO DOMINION BANK | $14482 | 198 | 0,00% | الأسهم |
| J.Safra Asset Management Corp | $11776 | 161 | 0,00% | الأسهم |
| Larson Financial Group LLC | $8996 | 123 | 0,00% | الأسهم |
| Sterling Capital Management LLC | $7241 | 99 | 0,00% | الأسهم |
| Smartleaf Asset Management LLC | $6854 | 92 | 0,00% | الأسهم |
| HRT FINANCIAL LP | $6642 | 90822 | 0,00% | الأسهم |
| Arax Advisory Partners | $6290 | 86 | 0,00% | الأسهم |
| CoreCap Advisors, LLC | $5705 | 78 | 0,00% | الأسهم |
| iA Global Asset Management Inc. | $4829 | 66023 | 0,00% | الأسهم |
| Optiver Holding B.V. | $4754 | 65 | 0,00% | الأسهم |
| Farther Finance Advisors, LLC | $3439 | 47 | 0,00% | الأسهم |
| Versant Capital Management, Inc | $3273 | 50 | 0,00% | الأسهم |
| Lindbrook Capital, LLC | $2879 | 58 | 0,00% | الأسهم |
| FIRST HORIZON CORP | $2633 | 36 | 0,00% | الأسهم |
| ROTHSCHILD INVESTMENT LLC | $2340 | 32 | 0,00% | الأسهم |
| Silver Grove Financial Group, Inc. | $1902 | 26 | 0,00% | الأسهم |
| FIFTH THIRD BANCORP | $1844 | 25 | 0,00% | الأسهم |
| COMERICA BANK | $1544 | 19 | 0,00% | الأسهم |
| Parkside Financial Bank & Trust | $1462 | 20 | 0,00% | الأسهم |
| Quarry LP | $1317 | 18 | 0,00% | الأسهم |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | $1287 | 17599 | 0,00% | الأسهم |
| JPL Wealth Management, LLC | $1244 | 17 | 0,00% | الأسهم |
| EverSource Wealth Advisors, LLC | $1243 | 17 | 0,00% | الأسهم |
| GSA CAPITAL PARTNERS LLP | $1194 | 16324 | 0,00% | الأسهم |
| Geneos Wealth Management Inc. | $951 | 13 | 0,00% | الأسهم |
| HUNTINGTON NATIONAL BANK | $878 | 12 | 0,00% | الأسهم |
| ASSETMARK, INC | $878 | 12 | 0,00% | الأسهم |
| Cornerstone Financial Management LLC | $805 | 11 | 0,00% | الأسهم |
| Bare Financial Services, Inc | $658 | 9 | 0,00% | الأسهم |
| SG Americas Securities, LLC | $563 | 7704 | 0,00% | الأسهم |
| Keating Financial Advisory Services, Inc. | $439 | 6 | 0,00% | الأسهم |
| Essential Partners LLC | $366 | 5 | 0,00% | الأسهم |
| Virtu Financial LLC | $343 | 4694 | 0,00% | الأسهم |
| Global Retirement Partners, LLC | $293 | 4 | 0,00% | الأسهم |
| Clearstead Advisors, LLC | $148 | 2 | 0,00% | الأسهم |
| Hughes Financial Services, LLC | $146 | 2 | 0,00% | الأسهم |
| Downshift Financial, LLC | $146 | 2 | 0,00% | الأسهم |
| KBC Group NV | $74 | 1011 | 0,00% | الأسهم |
| Fortitude Family Office, LLC | $73 | 1 | 0,00% | الأسهم |
| Wealth Enhancement Trust Services, Inc. | $73 | 1 | 0,00% | الأسهم |
| SBI Securities Co., Ltd. | $73 | 1 | 0,00% | الأسهم |
| IFP Advisors, Inc | $73 | 1 | 0,00% | الأسهم |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | $53 | 730 | 0,00% | الأسهم |
| Pacer Advisors, Inc. | $32 | 444 | 0,00% | الأسهم |
| Covestor Ltd | $1 | 7 | 0,00% | الأسهم |
| GW&K Investment Management, LLC | $1 | 16 | 0,00% | الأسهم |