SION — الملاك المؤسسيون (13F)
المؤسسات التي تبلغ عن حيازتها لهذا السهم في نموذج SEC 13F ربع السنوي الخاص بها. المراكز الطويلة فقط؛ قد يظهر مقدم واحد مرتين لأرجل خيارات منفصلة. الأرجل الكبيرة المتعاكسة من خيارات البيع/الشراء تعكس عادةً صناعة السوق أو المخزون المتحوط، وليس القناعة الاتجاهية.
| مؤسسة | القيمة | الأسهم | % من 13F المتتبعة | النوع |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $435722930 | 9905045 | 20,30% | الأسهم |
| TPG GP A, LLC | $285713378 | 6494962 | 13,31% | الأسهم |
| VIKING GLOBAL INVESTORS LP | $140556012 | 3195181 | 6,55% | الأسهم |
| Atlas Venture Life Science Advisors, LLC | $131776532 | 2995602 | 6,14% | الأسهم |
| ORBIMED ADVISORS LLC | $112433029 | 2555877 | 5,24% | الأسهم |
| ENAVATE SCIENCES GP, LLC | $109008540 | 2478030 | 5,08% | الأسهم |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $70384000 | 1600000 | 3,28% | الأسهم |
| BlackRock, Inc. | $64875089 | 1474769 | 3,02% | الأسهم |
| JPMORGAN CHASE & CO | $64085673 | 1490508 | 2,99% | الأسهم |
| JENNISON ASSOCIATES LLC | $51562131 | 1172133 | 2,40% | الأسهم |
| CITADEL ADVISORS LLC | $50484507 | 1147636 | 2,35% | الأسهم |
| VANGUARD CAPITAL MANAGEMENT LLC | $49796724 | 1132001 | 2,32% | الأسهم |
| VANGUARD GROUP INC | $48748883 | 1184951 | 2,27% | الأسهم |
| STATE STREET CORP | $44937281 | 1021534 | 2,09% | الأسهم |
| PERCEPTIVE ADVISORS LLC | $39810950 | 905000 | 1,85% | الأسهم |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $29953495 | 680916 | 1,40% | الأسهم |
| Siren, L.L.C. | $26856555 | 610515 | 1,25% | الأسهم |
| EVENTIDE ASSET MANAGEMENT, LLC | $20894402 | 474981 | 0,97% | الأسهم |
| GEODE CAPITAL MANAGEMENT, LLC | $20113984 | 457145 | 0,94% | الأسهم |
| Casdin Capital, LLC | $17596000 | 400000 | 0,82% | الأسهم |
| BAKER BROS. ADVISORS LP | $17596000 | 400000 | 0,82% | الأسهم |
| GOLDMAN SACHS GROUP INC | $17103752 | 388810 | 0,80% | الأسهم |
| Driehaus Capital Management LLC | $16955814 | 385447 | 0,79% | الأسهم |
| FRANKLIN RESOURCES INC | $12762071 | 290113 | 0,59% | الأسهم |
| Aberdeen Group plc | $12499231 | 284138 | 0,58% | الأسهم |
| FMR LLC | $12242065 | 278292 | 0,57% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $12173485 | 276733 | 0,57% | الأسهم |
| Candriam S.C.A. | $10248950 | 233208 | 0,48% | الأسهم |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $9807527 | 222949 | 0,46% | الأسهم |
| Kalehua Capital Management LLC | $8669197 | 197072 | 0,40% | الأسهم |
| Longaeva Partners L.P. | $8637524 | 196352 | 0,40% | الأسهم |
| Artisan Partners Limited Partnership | $8336017 | 189498 | 0,39% | الأسهم |
| Ensign Peak Advisors, Inc | $8117563 | 184532 | 0,38% | الأسهم |
| Soleus Capital Management, L.P. | $7816451 | 177687 | 0,36% | الأسهم |
| NORTHERN TRUST CORP | $6795399 | 154476 | 0,32% | الأسهم |
| MORGAN STANLEY | $6644558 | 151047 | 0,31% | الأسهم |
| Sofinnova Investments, Inc. | $6353564 | 144432 | 0,30% | الأسهم |
| Qube Research & Technologies Ltd | $6172193 | 140309 | 0,29% | الأسهم |
| Alyeska Investment Group, L.P. | $5992406 | 136222 | 0,28% | الأسهم |
| GordonMD Global Investments LP | $5982640 | 136000 | 0,28% | الأسهم |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $5707834 | 129753 | 0,27% | الأسهم |
| Sio Capital Management, LLC | $5622274 | 127808 | 0,26% | الأسهم |
| VANGUARD FIDUCIARY TRUST CO | $5342234 | 121442 | 0,25% | الأسهم |
| Artia Global Partners LP | $5267407 | 119741 | 0,25% | الأسهم |
| UBS Group AG | $5111902 | 116206 | 0,24% | الأسهم |
| First Turn Management, LLC | $4860587 | 110493 | 0,23% | الأسهم |
| CITIGROUP INC | $4846070 | 110163 | 0,23% | الأسهم |
| Ikarian Capital, LLC | $4728925 | 107500 | 0,22% | عقد خيار البيع |
| D. E. Shaw & Co., Inc. | $4471320 | 101644 | 0,21% | الأسهم |
| Rock Springs Capital Management LP | $4373882 | 99429 | 0,20% | الأسهم |
| Walleye Capital LLC | $4282295 | 97347 | 0,20% | الأسهم |
| Rhenman & Partners Asset Management AB | $4271429 | 97100 | 0,20% | الأسهم |
| BANK OF AMERICA CORP /DE/ | $3911063 | 88908 | 0,18% | الأسهم |
| AMERIPRISE FINANCIAL INC | $3617386 | 82232 | 0,17% | الأسهم |
| Integral Health Asset Management, LLC | $3299250 | 75000 | 0,15% | الأسهم |
| SUPERSTRING CAPITAL MANAGEMENT LP | $2778232 | 63156 | 0,13% | الأسهم |
| STEMPOINT CAPITAL LP | $2614150 | 59426 | 0,12% | الأسهم |
| DEUTSCHE BANK AG\ | $2346998 | 53353 | 0,11% | الأسهم |
| SEVEN GRAND MANAGERS, LLC | $2199500 | 50000 | 0,10% | الأسهم |
| Point72 Asset Management, L.P. | $2169939 | 49328 | 0,10% | الأسهم |
| TD Asset Management Inc | $2084950 | 47396 | 0,10% | الأسهم |
| ALPS ADVISORS INC | $2002645 | 45525 | 0,09% | الأسهم |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1868607 | 42478 | 0,09% | الأسهم |
| Russell Investments Group, Ltd. | $1858960 | 42258 | 0,09% | الأسهم |
| Bank of New York Mellon Corp | $1829361 | 41586 | 0,09% | الأسهم |
| Nuveen, LLC | $1814984 | 41259 | 0,08% | الأسهم |
| XTX Topco Ltd | $1675843 | 38096 | 0,08% | الأسهم |
| WELLINGTON MANAGEMENT GROUP LLP | $1643686 | 37365 | 0,08% | الأسهم |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $1582232 | 35968 | 0,07% | الأسهم |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1558126 | 35420 | 0,07% | الأسهم |
| BOOTHBAY FUND MANAGEMENT, LLC | $1429675 | 32500 | 0,07% | عقد خيار البيع |
| BNP PARIBAS FINANCIAL MARKETS | $1399014 | 31803 | 0,07% | الأسهم |
| Ishara Investments LP | $1350540 | 123000 | 0,06% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $1258114 | 28600 | 0,06% | عقد خيار البيع |
| Swiss National Bank | $1187730 | 27000 | 0,06% | الأسهم |
| Quadrature Capital Ltd | $1144752 | 26023 | 0,05% | الأسهم |
| Trexquant Investment LP | $1047402 | 23810 | 0,05% | الأسهم |
| NEW YORK STATE COMMON RETIREMENT FUND | $1037548 | 23586 | 0,05% | الأسهم |
| ALLIANCEBERNSTEIN L.P. | $1020291 | 25450 | 0,05% | الأسهم |
| TUDOR INVESTMENT CORP ET AL | $993074 | 22575 | 0,05% | الأسهم |
| RHUMBLINE ADVISERS | $981362 | 22309 | 0,05% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $879800 | 20000 | 0,04% | عقد خيار الشراء |
| Maven Securities LTD | $879800 | 20000 | 0,04% | الأسهم |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $820193 | 18645 | 0,04% | الأسهم |
| Susquehanna Portfolio Strategies, LLC | $793316 | 18034 | 0,04% | الأسهم |
| Rafferty Asset Management, LLC | $791996 | 18004 | 0,04% | الأسهم |
| Shay Capital LLC | $791820 | 18000 | 0,04% | الأسهم |
| WELLS FARGO & COMPANY/MN | $739955 | 16821 | 0,03% | الأسهم |
| Engineers Gate Manager LP | $686376 | 15603 | 0,03% | الأسهم |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $653339 | 14852 | 0,03% | الأسهم |
| KENNEDY CAPITAL MANAGEMENT LLC | $555198 | 12621 | 0,03% | الأسهم |
| MARSHALL WACE, LLP | $554230 | 12599 | 0,03% | الأسهم |
| Invesco Ltd. | $546267 | 12418 | 0,03% | الأسهم |
| MetLife Investment Management, LLC | $482658 | 10972 | 0,02% | الأسهم |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $463369 | 10582 | 0,02% | الأسهم |
| Jump Financial, LLC | $460708 | 10473 | 0,02% | الأسهم |
| VANGUARD ASSET MANAGEMENT, Ltd | $419445 | 9535 | 0,02% | الأسهم |
| PROFUND ADVISORS LLC | $402069 | 9140 | 0,02% | الأسهم |
| Virtus Investment Advisers, LLC | $400705 | 9109 | 0,02% | الأسهم |
| Legal & General Group Plc | $397846 | 9044 | 0,02% | الأسهم |
| CITADEL ADVISORS LLC | $369516 | 8400 | 0,02% | عقد خيار البيع |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $356319 | 8100 | 0,02% | عقد خيار الشراء |
| Vanguard Global Advisers, LLC | $345409 | 7852 | 0,02% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $338723 | 7700 | 0,02% | عقد خيار البيع |
| China Universal Asset Management Co., Ltd. | $316112 | 7186 | 0,01% | الأسهم |
| Quarry LP | $296933 | 6750 | 0,01% | الأسهم |
| BARCLAYS PLC | $285715 | 6495 | 0,01% | الأسهم |
| VARCOV Co. | $282328 | 6418 | 0,01% | الأسهم |
| Police & Firemen's Retirement System of New Jersey | $239218 | 5438 | 0,01% | الأسهم |
| Squarepoint Ops LLC | $238206 | 5415 | 0,01% | الأسهم |
| INTECH INVESTMENT MANAGEMENT LLC | $229540 | 5218 | 0,01% | الأسهم |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $229408 | 5215 | 0,01% | الأسهم |
| SEI INVESTMENTS CO | $226900 | 5158 | 0,01% | الأسهم |
| Verition Fund Management LLC | $219950 | 5000 | 0,01% | عقد خيار الشراء |
| AlphaCentric Advisors LLC | $213923 | 4863 | 0,01% | الأسهم |
| Jain Global LLC | $210272 | 4780 | 0,01% | الأسهم |
| AXQ CAPITAL, LP | $202222 | 4597 | 0,01% | الأسهم |
| STRS OHIO | $153965 | 3500 | 0,01% | الأسهم |
| Vanguard Investments Australia, Ltd. | $153525 | 3490 | 0,01% | الأسهم |
| KLP KAPITALFORVALTNING AS | $136369 | 3100 | 0,01% | الأسهم |
| Mirae Asset Global Investments Co., Ltd. | $88816 | 2019 | 0,00% | الأسهم |
| Quantbot Technologies LP | $80062 | 1820 | 0,00% | الأسهم |
| Ameritas Investment Partners, Inc. | $73595 | 1673 | 0,00% | الأسهم |
| Tower Research Capital LLC (TRC) | $56263 | 1279 | 0,00% | الأسهم |
| Mitsubishi UFJ Asset Management Co., Ltd. | $43990 | 1000 | 0,00% | الأسهم |
| GF FUND MANAGEMENT CO. LTD. | $41615 | 946 | 0,00% | الأسهم |
| State of Wyoming | $35368 | 804 | 0,00% | الأسهم |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $31189 | 709 | 0,00% | الأسهم |
| ROYAL BANK OF CANADA | $25000 | 568 | 0,00% | الأسهم |
| PRICE T ROWE ASSOCIATES INC /MD/ | $21029 | 478016 | 0,00% | الأسهم |
| NISA INVESTMENT ADVISORS, LLC | $16936 | 385 | 0,00% | الأسهم |
| GAMMA Investing LLC | $10734 | 244 | 0,00% | الأسهم |
| Federation des caisses Desjardins du Quebec | $9238 | 210 | 0,00% | الأسهم |
| Farther Finance Advisors, LLC | $8622 | 196 | 0,00% | الأسهم |
| Rockefeller Capital Management L.P. | $5015 | 114 | 0,00% | الأسهم |
| Hurley Capital, LLC | $4971 | 113 | 0,00% | الأسهم |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $4650 | 116 | 0,00% | الأسهم |
| US BANCORP \DE\ | $4575 | 104 | 0,00% | الأسهم |
| Sterling Capital Management LLC | $2859 | 65 | 0,00% | الأسهم |
| CWM, LLC | $2686 | 67 | 0,00% | الأسهم |
| Arax Advisory Partners | $1804 | 41 | 0,00% | الأسهم |
| Bare Financial Services, Inc | $1628 | 37 | 0,00% | الأسهم |
| Caitong International Asset Management Co., Ltd | $1364 | 31 | 0,00% | الأسهم |
| Hughes Financial Services, LLC | $1100 | 25 | 0,00% | الأسهم |
| EverSource Wealth Advisors, LLC | $880 | 20 | 0,00% | الأسهم |
| Fortitude Family Office, LLC | $660 | 15 | 0,00% | الأسهم |
| SJS Investment Consulting Inc. | $396 | 9 | 0,00% | الأسهم |
| CONTRAVISORY INVESTMENT MANAGEMENT, INC. | $264 | 6 | 0,00% | الأسهم |
| PNC Financial Services Group, Inc. | $220 | 5 | 0,00% | الأسهم |
| Steward Partners Investment Advisory, LLC | $176 | 4 | 0,00% | الأسهم |
| NATIONAL BANK OF CANADA /FI/ | $88 | 2 | 0,00% | الأسهم |
| ROTHSCHILD INVESTMENT LLC | $44 | 1 | 0,00% | الأسهم |
| Allworth Financial LP | $44 | 1 | 0,00% | الأسهم |
| Pacer Advisors, Inc. | $13 | 301 | 0,00% | الأسهم |
| Covestor Ltd | $1 | 12 | 0,00% | الأسهم |