UPB — الملاك المؤسسيون (13F)
المؤسسات التي تبلغ عن حيازتها لهذا السهم في نموذج SEC 13F ربع السنوي الخاص بها. المراكز الطويلة فقط؛ قد يظهر مقدم واحد مرتين لأرجل خيارات منفصلة. الأرجل الكبيرة المتعاكسة من خيارات البيع/الشراء تعكس عادةً صناعة السوق أو المخزون المتحوط، وليس القناعة الاتجاهية.
| مؤسسة | القيمة | الأسهم | % من 13F المتتبعة | النوع |
|---|---|---|---|---|
| VANGUARD GROUP INC | $64846119 | 2388439 | 15,74% | الأسهم |
| FMR LLC | $56487247 | 8162897 | 13,71% | الأسهم |
| ORBIMED ADVISORS LLC | $39399636 | 5693589 | 9,56% | الأسهم |
| NORGES BANK | $26078843 | 3768619 | 6,33% | الأسهم |
| BlackRock, Inc. | $25973237 | 3753358 | 6,30% | الأسهم |
| Decheng Capital LLC | $18856087 | 2724868 | 4,58% | الأسهم |
| ENAVATE SCIENCES GP, LLC | $17021145 | 2459703 | 4,13% | الأسهم |
| VANGUARD CAPITAL MANAGEMENT LLC | $12986999 | 1876734 | 3,15% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $7914923 | 1143775 | 1,92% | الأسهم |
| D. E. Shaw & Co., Inc. | $7169425 | 1036044 | 1,74% | الأسهم |
| JPMORGAN CHASE & CO | $7013464 | 1012044 | 1,70% | الأسهم |
| Qube Research & Technologies Ltd | $6771220 | 978500 | 1,64% | الأسهم |
| Parkman Healthcare Partners LLC | $6471909 | 935247 | 1,57% | الأسهم |
| GEODE CAPITAL MANAGEMENT, LLC | $6445888 | 931261 | 1,56% | الأسهم |
| SEB Asset Management AB | $6079022 | 878473 | 1,48% | الأسهم |
| Woodline Partners LP | $5753849 | 831481 | 1,40% | الأسهم |
| STATE STREET CORP | $5302955 | 766323 | 1,29% | الأسهم |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4931656 | 712667 | 1,20% | الأسهم |
| Y-Intercept (Hong Kong) Ltd | $4799401 | 693555 | 1,16% | الأسهم |
| Bain Capital Life Sciences Investors, LLC | $4158567 | 600949 | 1,01% | الأسهم |
| AQR CAPITAL MANAGEMENT LLC | $3770493 | 544869 | 0,92% | الأسهم |
| MORGAN STANLEY | $3630453 | 524632 | 0,88% | الأسهم |
| BNP PARIBAS FINANCIAL MARKETS | $3539898 | 511546 | 0,86% | الأسهم |
| Walleye Capital LLC | $3449551 | 498490 | 0,84% | الأسهم |
| Trexquant Investment LP | $3227696 | 466430 | 0,78% | الأسهم |
| Point72 Asset Management, L.P. | $3134836 | 453011 | 0,76% | الأسهم |
| BANK OF AMERICA CORP /DE/ | $2710993 | 391762 | 0,66% | الأسهم |
| DIMENSIONAL FUND ADVISORS LP | $2640811 | 381613 | 0,64% | الأسهم |
| Altshuler Shaham Ltd | $2630022 | 380061 | 0,64% | الأسهم |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $2475672 | 357756 | 0,60% | الأسهم |
| SAMSARA BIOCAPITAL, LLC | $2447722 | 353717 | 0,59% | الأسهم |
| Propel Bio Management, LLC | $2424692 | 350389 | 0,59% | الأسهم |
| WELLINGTON MANAGEMENT GROUP LLP | $2369083 | 342353 | 0,57% | الأسهم |
| NORTHERN TRUST CORP | $2057634 | 297346 | 0,50% | الأسهم |
| Squarepoint Ops LLC | $2013056 | 290904 | 0,49% | الأسهم |
| Voleon Capital Management LP | $1973819 | 285234 | 0,48% | الأسهم |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1816196 | 262456 | 0,44% | الأسهم |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1751397 | 253092 | 0,43% | الأسهم |
| GOLDMAN SACHS GROUP INC | $1708666 | 246917 | 0,41% | الأسهم |
| XTX Topco Ltd | $1677034 | 242346 | 0,41% | الأسهم |
| DEUTSCHE BANK AG\ | $1670814 | 241447 | 0,41% | الأسهم |
| VANGUARD FIDUCIARY TRUST CO | $1658143 | 239616 | 0,40% | الأسهم |
| UBS Group AG | $1624221 | 234714 | 0,39% | الأسهم |
| Schonfeld Strategic Advisors LLC | $1562258 | 225760 | 0,38% | الأسهم |
| Jump Financial, LLC | $1544703 | 223223 | 0,37% | الأسهم |
| SPHERA FUNDS MANAGEMENT LTD. | $1520324 | 219700 | 0,37% | الأسهم |
| Boxer Capital Management, LLC | $1038000 | 150000 | 0,25% | الأسهم |
| RENAISSANCE TECHNOLOGIES LLC | $908596 | 131300 | 0,22% | الأسهم |
| EntryPoint Capital, LLC | $895766 | 129446 | 0,22% | الأسهم |
| ALGERT GLOBAL LLC | $820920 | 118630 | 0,20% | الأسهم |
| Bank of New York Mellon Corp | $593369 | 85747 | 0,14% | الأسهم |
| Nuveen, LLC | $586608 | 84770 | 0,14% | الأسهم |
| AMERICAN CENTURY COMPANIES INC | $541102 | 78194 | 0,13% | الأسهم |
| Man Group plc | $510855 | 73823 | 0,12% | الأسهم |
| ALLIANCEBERNSTEIN L.P. | $465120 | 51680 | 0,11% | الأسهم |
| Simplify Asset Management Inc. | $429822 | 62113 | 0,10% | الأسهم |
| ALPS ADVISORS INC | $382178 | 55228 | 0,09% | الأسهم |
| Quantinno Capital Management LP | $379479 | 54838 | 0,09% | الأسهم |
| Virtus Investment Advisers, LLC | $371175 | 53638 | 0,09% | الأسهم |
| Invesco Ltd. | $369508 | 53397 | 0,09% | الأسهم |
| Brevan Howard Capital Management LP | $348553 | 50369 | 0,08% | الأسهم |
| Swiss National Bank | $332852 | 48100 | 0,08% | الأسهم |
| Russell Investments Group, Ltd. | $329000 | 47543 | 0,08% | الأسهم |
| Allspring Global Investments Holdings, LLC | $298819 | 43182 | 0,07% | الأسهم |
| RHUMBLINE ADVISERS | $293288 | 42384 | 0,07% | الأسهم |
| TWO SIGMA INVESTMENTS, LP | $292889 | 42325 | 0,07% | الأسهم |
| ExodusPoint Capital Management, LP | $284031 | 41045 | 0,07% | الأسهم |
| CITIGROUP INC | $279145 | 40339 | 0,07% | الأسهم |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $267347 | 38634 | 0,06% | الأسهم |
| Stonepine Capital Management, LLC | $231349 | 33432 | 0,06% | الأسهم |
| Mariner, LLC | $229337 | 33141 | 0,06% | الأسهم |
| WELLS FARGO & COMPANY/MN | $204119 | 29497 | 0,05% | الأسهم |
| BARCLAYS PLC | $202120 | 29208 | 0,05% | الأسهم |
| Creative Planning | $197102 | 28483 | 0,05% | الأسهم |
| Quantbot Technologies LP | $194992 | 28178 | 0,05% | الأسهم |
| AXQ CAPITAL, LP | $187311 | 27068 | 0,05% | الأسهم |
| nVerses Capital, LLC | $166280 | 24029 | 0,04% | الأسهم |
| DNB Asset Management AS | $163312 | 23600 | 0,04% | الأسهم |
| VANGUARD ASSET MANAGEMENT, Ltd | $157250 | 22724 | 0,04% | الأسهم |
| Graham Capital Management, L.P. | $155755 | 22508 | 0,04% | الأسهم |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $154904 | 22385 | 0,04% | الأسهم |
| Verdad Advisers, LP | $150925 | 21810 | 0,04% | الأسهم |
| MetLife Investment Management, LLC | $144296 | 20852 | 0,04% | الأسهم |
| SEI INVESTMENTS CO | $138580 | 20026 | 0,03% | الأسهم |
| WINTON GROUP Ltd | $137016 | 19800 | 0,03% | الأسهم |
| IEQ CAPITAL, LLC | $135182 | 19535 | 0,03% | الأسهم |
| DIADEMA PARTNERS LP | $132124 | 19093 | 0,03% | الأسهم |
| Shay Capital LLC | $124560 | 18000 | 0,03% | الأسهم |
| Quadrature Capital Ltd | $124477 | 17988 | 0,03% | الأسهم |
| Entropy Technologies, LP | $121391 | 17542 | 0,03% | الأسهم |
| STATE OF WISCONSIN INVESTMENT BOARD | $118090 | 17065 | 0,03% | الأسهم |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $112222 | 16217 | 0,03% | الأسهم |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $108886 | 15735 | 0,03% | الأسهم |
| JANE STREET GROUP, LLC | $107910 | 15594 | 0,03% | الأسهم |
| CITADEL ADVISORS LLC | $103800 | 15000 | 0,03% | عقد خيار الشراء |
| MERCER GLOBAL ADVISORS INC /ADV | $92396 | 13352 | 0,02% | الأسهم |
| Vanguard Global Advisers, LLC | $90368 | 13059 | 0,02% | الأسهم |
| Legal & General Group Plc | $86922 | 12561 | 0,02% | الأسهم |
| Engineers Gate Manager LP | $86438 | 12491 | 0,02% | الأسهم |
| STRS OHIO | $83040 | 12000 | 0,02% | الأسهم |
| JANE STREET GROUP, LLC | $82348 | 11900 | 0,02% | عقد خيار الشراء |
| CANADA PENSION PLAN INVESTMENT BOARD | $79580 | 11500 | 0,02% | الأسهم |
| HSBC HOLDINGS PLC | $77602 | 10793 | 0,02% | الأسهم |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $75428 | 10017 | 0,02% | الأسهم |
| PRELUDE CAPITAL MANAGEMENT, LLC | $73006 | 10550 | 0,02% | الأسهم |
| AMERIPRISE FINANCIAL INC | $72570 | 10487 | 0,02% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $69892 | 10100 | 0,02% | عقد خيار الشراء |
| Police & Firemen's Retirement System of New Jersey | $65436 | 9456 | 0,02% | الأسهم |
| China Universal Asset Management Co., Ltd. | $59934 | 8661 | 0,01% | الأسهم |
| KLP KAPITALFORVALTNING AS | $40828 | 5900 | 0,01% | الأسهم |
| NEW YORK STATE COMMON RETIREMENT FUND | $35984 | 5200 | 0,01% | الأسهم |
| CWM, LLC | $34947 | 3883 | 0,01% | الأسهم |
| Persistent Asset Partners Ltd | $33597 | 4855 | 0,01% | الأسهم |
| Tower Research Capital LLC (TRC) | $33133 | 4788 | 0,01% | الأسهم |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $32524 | 4700 | 0,01% | الأسهم |
| NISA INVESTMENT ADVISORS, LLC | $29604 | 4278 | 0,01% | الأسهم |
| Vanguard Investments Australia, Ltd. | $28344 | 4096 | 0,01% | الأسهم |
| Ameritas Investment Partners, Inc. | $18968 | 2741 | 0,00% | الأسهم |
| Mirae Asset Global Investments Co., Ltd. | $16843 | 2434 | 0,00% | الأسهم |
| Global Retirement Partners, LLC | $12940 | 1870 | 0,00% | الأسهم |
| Arax Advisory Partners | $12255 | 1771 | 0,00% | الأسهم |
| GAMMA Investing LLC | $8055 | 1164 | 0,00% | الأسهم |
| GF FUND MANAGEMENT CO. LTD. | $7923 | 1145 | 0,00% | الأسهم |
| ROYAL BANK OF CANADA | $7000 | 1091 | 0,00% | الأسهم |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $6678 | 965 | 0,00% | الأسهم |
| Quarry LP | $6180 | 893 | 0,00% | الأسهم |
| Allworth Financial LP | $5384 | 778 | 0,00% | الأسهم |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $5292 | 588 | 0,00% | الأسهم |
| Rockefeller Capital Management L.P. | $5107 | 738 | 0,00% | الأسهم |
| Sterling Capital Management LLC | $4913 | 710 | 0,00% | الأسهم |
| PNC Financial Services Group, Inc. | $2678 | 387 | 0,00% | الأسهم |
| Farther Finance Advisors, LLC | $2443 | 353 | 0,00% | الأسهم |
| ROTHSCHILD INVESTMENT LLC | $1986 | 287 | 0,00% | الأسهم |
| EverSource Wealth Advisors, LLC | $1882 | 272 | 0,00% | الأسهم |
| US BANCORP \DE\ | $1827 | 264 | 0,00% | الأسهم |
| IFP Advisors, Inc | $1675 | 242 | 0,00% | الأسهم |
| Torren Management, LLC | $1458 | 162 | 0,00% | الأسهم |
| ACADIAN ASSET MANAGEMENT LLC | $1208 | 175110 | 0,00% | الأسهم |
| HRT FINANCIAL LP | $1180 | 170590 | 0,00% | الأسهم |
| Physician Wealth Advisors, Inc. | $1108 | 160 | 0,00% | الأسهم |
| Essential Partners LLC | $1010 | 146 | 0,00% | الأسهم |
| N.E.W. Advisory Services LLC | $830 | 120 | 0,00% | الأسهم |
| SJS Investment Consulting Inc. | $526 | 76 | 0,00% | الأسهم |
| GSA CAPITAL PARTNERS LLP | $480 | 69348 | 0,00% | الأسهم |
| PRICE T ROWE ASSOCIATES INC /MD/ | $195 | 28058 | 0,00% | الأسهم |
| Silver Grove Financial Group, Inc. | $194 | 28 | 0,00% | الأسهم |
| SG Americas Securities, LLC | $141 | 20338 | 0,00% | الأسهم |
| SIMPLEX TRADING, LLC | $138 | 20 | 0,00% | الأسهم |
| OSAIC HOLDINGS, INC. | $131 | 19 | 0,00% | الأسهم |
| Clearstead Advisors, LLC | $105 | 15 | 0,00% | الأسهم |
| JPL Wealth Management, LLC | $97 | 14 | 0,00% | الأسهم |
| Freestone Grove Partners LP | $7 | 1 | 0,00% | الأسهم |
| NATIONAL BANK OF CANADA /FI/ | $7 | 1 | 0,00% | الأسهم |
| Covestor Ltd | $0 | 39 | 0,00% | الأسهم |