FULC
NASDAQ
US
Fulcrum Therapeutics, Inc. - Common Stock
$8.04
▲ +$0.56
(+7.49%)
Vol 1.0M
5
Quality Score
fail
Rev ✗
NI ✗
>IPO ✗
Mkt Cap
$746.1M
ROE
-24.5%
Margin
8.1%
D/E
0.00
Beta
3.20
52W
$2–$16
Wall Street Consensus
16 analysts · Apr 20265
Strong Buy
8
Buy
2
Hold
1
Sell
0
Strong Sell
81.2%
Buy Rating
Price Chart
Similar Stocks
Earnings
Beat rate: 75.0%| Quarter | EPS Est | EPS Act | Surprise |
|---|---|---|---|
| Dec 2025 | $-0.32 | $-0.31 | +$0.01 |
| Sep 2025 | $-0.30 | $-0.31 | $-0.01 |
| Jun 2025 | $-0.30 | $-0.28 | +$0.02 |
| Mar 2025 | $-0.30 | $-0.28 | +$0.02 |
Quarterly Revenue & Earnings
| Quarter | 2024-0… | 2024-1… | 2025-0… | 2025-0… | 2025-0… | 2025-1… |
|---|---|---|---|---|---|---|
| Revenue | — | — | — | — | — | — |
| Net Income | — | -$16.6M | -$17.7M | -$17.3M | -$19.6M | -$20.3M |
Fundamentals Trend
| Metric | 2025-06-30 | 2025-09-02 | 2025-10-02 | 2025-11-03 | 2025-12-03 | 2026-01-02 |
|---|---|---|---|---|---|---|
| ROE (TTM) | -23.3% | -23.3% | -23.3% | -23.3% | -24.5% | -24.5% |
| P/E (TTM) | — | — | — | — | — | — |
| Net Margin | — | 8.1% | 8.1% | 8.1% | 8.1% | 8.1% |
| Gross Margin | — | — | — | — | — | — |
| D/E Ratio | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Current Ratio | 24.42 | 24.42 | 24.42 | 24.42 | 17.70 | 17.70 |
Key Ratios
ROA (TTM)
-22.8%
P/S (TTM)
9.14
P/B
1.0
EPS (TTM)
$-0.86
CF/Share
$-1.64
Rev Growth 3Y
+61.0%
52W High
$15.74
52W Low
$2.32
$2.32
52-Week Range
$15.74
Financial Health
Free Cash Flow
-$17.0M
Net Debt
-$191.1M
Cash
$197.5M
Total Debt
$6.4M
As of Dec 31, 2025
How does FULC compare to Pharmaceuticals peers?
Peer group: Micro-cap Pharmaceuticals (All) · 171 companies
FULC valuation vs Pharmaceuticals peers
P/E ratio
—
▼
0%
below
peers
(22.4)
vs Peers
vs Industry
Undervalued
P/S ratio
9.1
▲
85%
above
peers
(5.0)
vs Peers
vs Industry
Pricier
P/B ratio
1.0
▼
51%
below
peers
(2.1)
vs Peers
vs Industry
Undervalued
Div yield
—
▼
0%
below
peers
(2.0%)
vs Peers
vs Industry
Low yield
FULC profitability vs Pharmaceuticals peers
ROE
-24.5%
▲
55%
above
peers
(-54.3%)
vs Peers
vs Industry
Below avg
Net margin
8.1%
▲
117%
above
peers
(-47.4%)
vs Peers
vs Industry
Below avg
Gross margin
—
▼
0%
below
peers
(68.3%)
vs Peers
vs Industry
In line
ROA
-22.8%
▲
39%
above
peers
(-37.4%)
vs Peers
vs Industry
Below avg
FULC financial health vs Pharmaceuticals peers
D/E ratio
0.0
▼
100%
below
peers
(1.5)
vs Peers
vs Industry
Low debt
Current ratio
17.7
▲
427%
above
peers
(3.4)
vs Peers
vs Industry
Strong liquidity
Beta
3.2
▲
241%
above
peers
(0.9)
vs Peers
vs Industry
More volatile
FULC fundamentals radar
FULC
Peer median
Industry
FULC profitability vs leverage
Bubble size = market cap · X = net margin · Y = D/E ratio
FULC vs peers: key metrics
Insider Activity
NeutralBuys
0
Sells
0
GOULD ROBERT J.
Director · Feb 02
15000 shs
Last 90 days
Top Holders
Top 5: 39.67%Suvretta Capital Management…
9.85%
$44.2M
RA Capital Management, L.P.
9.09%
$40.7M
TCG Crossover Management, L…
7.88%
$35.3M
Nantahala Capital Managemen…
6.45%
$28.9M
Blackrock Inc.
6.40%
$28.7M
As of Dec 31, 2025
Latest News
No related news yet