NCNA NuCana plc - American Depositary Shares

NASDAQ · Biotechnology
$1.56
Price · Aug 19, 2026

NCNA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$1.56
Market Cap
P/E (TTM)
EPS (TTM)
Revenue (TTM)
Div Yield
ROE
Debt/Equity
52W Range
$1 – $7

NCNA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
EPS
Free Cash Flow
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
NCNA
Peer Median

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
NCNA
Peer Median

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
NCNA
Peer Median

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
NCNA
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
NCNA
Peer Median

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
NCNA
Peer Median

NCNA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 8 analysts
  • Strong Buy 3 37.5%
  • Buy 3 37.5%
  • Hold 2 25.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-74.6%
Period EPS Actual EPS Est Surprise
Sept. 30, 2024 $-350.00 $-545.51 195.5%
June 30, 2024 $-600.00 $-369.08 -230.9%
March 31, 2024 $-650.00 $-564.79 -85.2%
Dec. 31, 2023 $-700.00 $-522.30 -177.7%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
NCNA
ROIV $19.95B -51.3 -71.6% -3629.2% -6.5%

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Institutional owners (13F) 11 filers · $143K total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
5 (+2 vs prior Q) 2 (-2 vs prior Q) 3 (+3 vs prior Q) 0 (-2 vs prior Q) +55K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
StoneX Group Inc. $71,510 47,043 49.92% Shares
CITADEL ADVISORS LLC $41,190 27,099 28.75% Shares
Glass Jacobson Investment Advisors llc $22,800 15,000 15.92% Shares
RHUMBLINE ADVISERS $7,139 4,698 4.98% Shares
Integrated Wealth Concepts LLC $286 188 0.20% Shares
CITIGROUP INC $286 188 0.20% Shares
HRT FINANCIAL LP $25 16,870 0.02% Shares
Caitong International Asset Management Co., Ltd $8 5 0.01% Shares
MORGAN STANLEY $3 2 0.00% Shares
SBI Securities Co., Ltd. $2 1 0.00% Shares
ACADIAN ASSET MANAGEMENT LLC $0 2 0.00% Shares

Company insiders 3 insiders · 2 officers · 1 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Theresa Margaret Ms Bruce Chief Operating Officer April 15, 2026 A 0 0 $0
Jeffrey D. Bloss Chief Medical Officer June 19, 2026 D 0 0 $0
Elliott M. Levy Director June 19, 2026 D 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 6 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Hugh S. Griffith March 18, 2026 12.00% Initial filing Passive investment SEC
Sofinnova Venture Partners VIII, L.P., Sofinnova Management VIII, L.L.C., Sofinnova Venture Partners X, L.P., Sofinnova Management X, L.P., Sofinnova Management X-A, L.L.C., Dr. James I. Healy, Dr. Maha Katabi Feb. 25, 2025 0.10% Amendment Passive investment SEC
Sofinnova Capital VI FCPR, Sofinnova Partners SAS, Antoine Papiernik, Henrijette Richter, Maina Bhaman, Graziano Seghezzi, Anta Gkelou, Karl Naegler Feb. 14, 2025 5.10% Amendment Passive investment SEC
Sofinnova Venture Partners VIII, L.P. (“SVP VIII”), Sofinnova Management VIII, L.L.C. (“SM VIII”), Dr. James I. Healy (“Healy”), Dr. Maha Katabi (“Katabi”), Sofinnova Venture Partners X, L.P. (“SVP X”), Sofinnova Management X, L.P. (“SM X LP”), Sofinnova Management X- A , L.L.C. (“SM X LLC”) ×4 filings Feb. 27, 2024 Initial filing Passive investment SEC
Sofinnova Capital VI FCPR (“SC VI”), Sofinnova Partners SAS, a French corporation (“SP SAS”), Denis Lucquin (“Lucquin”), Antoine Papiernik (“Papiernik”), Henrijette Richter (“Richter”), Monique Saulnier (“Saulnier”), Graziano Seghezzi (“Seghezzi”) ×6 filings June 15, 2021 Initial filing SEC
Abingworth LLP, Abingworth Bioventures VII, LP Sept. 28, 2020 Initial filing Board campaign SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.