Insider at

04

Insider transactions

05
0 buys (P) 7 sells (S) Net: $-1,691,387 + 56 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

56 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
April 2, 2026 AGIO S 10b5-1 12,472 $34.71 $432,903 177,604 Direct -6.56% Disposed -8.4% (price as of 2026-10-02)
April 2, 2026 AGIO S 10b5-1 6,596 $34.71 $228,947 184,508 Direct -3.45% Disposed -8.4% (price as of 2026-10-02)
March 2, 2026 AGIO S 10b5-1 3,870 $28.96 $112,075 147,733 Direct -2.55% Disposed 9.8% (price as of 2026-10-02)
March 2, 2026 AGIO S 10b5-1 8,267 $28.96 $239,412 157,466 Direct -4.99% Disposed 9.8% (price as of 2026-10-02)
March 2, 2026 AGIO S 10b5-1 5,918 $28.96 $171,385 164,548 Direct -3.47% Disposed 9.8% (price as of 2026-10-02)
Dec. 30, 2025 AGIO S 10b5-1 12,473 $27.09 $337,894 136,583 Direct -8.37% Disposed 17.4% (price as of 2026-10-02)
Dec. 30, 2025 AGIO S 10b5-1 6,230 $27.09 $168,771 143,103 Direct -4.17% Disposed 17.4% (price as of 2026-10-02)
Aug. 8, 2025 AGIO S 10b5-1 11,085 $36.67 $406,487 123,528 Direct -8.23% Disposed -13.3% (price as of 2026-10-02)
June 24, 2025 AGIO S 10b5-1 12,471 $33.54 $418,277 105,401 Direct -10.58% Disposed -5.2% (price as of 2026-10-02)
June 24, 2025 AGIO S 10b5-1 6,229 $33.54 $208,921 111,922 Direct -5.27% Disposed -5.2% (price as of 2026-10-02)
March 3, 2025 AGIO S 10b5-1 4,153 $35.54 $147,598 83,139 Direct -4.76% Disposed -10.5% (price as of 2026-10-02)
March 3, 2025 AGIO S 10b5-1 8,794 $35.54 $312,539 92,345 Direct -8.69% Disposed -10.5% (price as of 2026-10-02)
Aug. 8, 2024 AGIO S 10b5-1 11,091 $42.75 $474,140 78,792 Direct -12.34% Disposed -25.6% (price as of 2026-10-02)
June 5, 2024 AGIO S 10b5-1 12,115 $48.84 $591,697 67,192 Direct -15.28% Disposed -34.9% (price as of 2026-10-02)
March 5, 2024 AGIO S 10b5-1 4,156 $32.57 $135,361 53,780 Direct -7.17% Disposed -2.4% (price as of 2026-10-02)
Jan. 24, 2024 AGIO S 10b5-1 7,635 $21.64 $165,221 49,436 Direct -13.38% Disposed 47.0% (price as of 2026-10-02)
Jan. 9, 2024 AGIO S 10b5-1 12,066 $22.99 $277,397 40,053 Direct -23.15% Disposed 38.3% (price as of 2026-10-02)
Aug. 8, 2023 AGIO S 10,178 $25.48 $259,335 26,592 Direct -27.68% Disposed 24.8% (price as of 2026-10-02)
June 30, 2023 AGIO S 11,449 $28.36 $324,694 14,079 Direct -44.85% Disposed 12.1% (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
June 18, 2026 AGIO Restricted stock units Common stock (39,000) · · 39,000 Acquired
June 18, 2026 AGIO Performance share units Common stock (39,000) · · 39,000 Disposed
June 9, 2026 NTLA Stock Option (right to buy) Common Stock (13,300) $12.89 June 8, 2036 13,300 Acquired
April 2, 2026 AGIO Performance share units Common stock (25,528) · · 25,528 Disposed
April 2, 2026 AGIO Performance share units Common stock (13,500) · · 13,500 Disposed
March 2, 2026 AGIO Restricted stock units Common stock (8,500) · · 8,500 Disposed
March 2, 2026 AGIO Restricted stock units Common stock (18,000) · · 18,000 Disposed
March 2, 2026 AGIO Restricted stock units Common stock (13,000) · · 13,000 Disposed
March 1, 2026 AGIO Restricted stock units Common stock (48,000) · · 48,000 Acquired
March 1, 2026 AGIO Stock options (right to buy) Common stock (174,000) $30.23 March 1, 2036 174,000 Acquired
Dec. 30, 2025 AGIO Performance share units Common stock (25,528) · · 25,528 Disposed
Dec. 30, 2025 AGIO Performance share units Common stock (12,750) · · 12,750 Disposed
Aug. 8, 2025 AGIO Restricted stock units Common stock (22,691) · · 22,691 Disposed
June 24, 2025 AGIO Performance share units Common stock (25,527) · · 25,527 Disposed
June 24, 2025 AGIO Performance share units Common stock (12,750) · · 12,750 Disposed
June 11, 2025 NTLA Stock Option (right to buy) Common Stock (11,450) $8.37 June 10, 2035 11,450 Acquired
March 1, 2025 AGIO Restricted stock units Common stock (39,000) · · 39,000 Acquired
March 1, 2025 AGIO Stock options (right to buy) Common stock (142,500) $35.54 March 1, 2035 142,500 Acquired
March 1, 2025 AGIO Restricted stock units Common stock (8,500) · · 8,500 Disposed
March 1, 2025 AGIO Restricted stock units Common stock (18,000) · · 18,000 Disposed
Aug. 8, 2024 AGIO Restricted stock units Common stock (22,691) · · 22,691 Disposed
June 13, 2024 NTLA Stock Option (right to buy) Common Stock (22,297) $25.96 June 12, 2034 22,297 Acquired
June 5, 2024 AGIO Performance share units Common stock (25,527) · · 25,527 Disposed
March 1, 2024 AGIO Restricted stock units Common stock (54,000) · · 54,000 Acquired
March 1, 2024 AGIO Stock options (right to buy) Common stock (195,500) $32.27 March 1, 2034 195,500 Acquired
March 1, 2024 AGIO Restricted stock units Common stock (8,500) · · 8,500 Disposed
Jan. 20, 2024 AGIO Performance share units Common stock (17,018) · · 17,018 Disposed
Jan. 5, 2024 AGIO Performance share units Common stock (25,527) · · 25,527 Disposed
Aug. 8, 2023 AGIO Restricted stock units Common stock (22,691) · · 22,691 Disposed
June 28, 2023 AGIO Performance share units Common stock (25,528) · · 25,528 Disposed
March 1, 2023 AGIO Restricted stock units Common stock (25,500) · · 25,500 Acquired
March 1, 2023 AGIO Stock options (right to buy) Common stock (94,500) $25.01 March 1, 2033 94,500 Acquired
Aug. 8, 2022 AGIO Stock option (right to buy) Common stock (561,083) $29.38 Aug. 8, 2032 561,083 Acquired
Aug. 8, 2022 AGIO Restricted stock units Common stock (68,073) · · 68,073 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Compensation (DEF 14A)

08

Matched by name from proxy statements (DEF 14A) — verify against the filing.

Fiscal yearSalaryBonusStock awards Option awardsNon-equity incentivePension changeOtherTotal
2025 $846,864 · · · $592,804 · $11,789 $5,370,389
2024 $822,198 · · · $719,423 · $11,653 $6,776,359
2023 $798,250 · · · $648,179 · $12,546 $3,416,453

Figures from the Summary Compensation Table of the company's proxy statement (DEF 14A). Compensation is not a recommendation.