AGIO Agios Pharmaceuticals, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$33.46
Price · Aug 18, 2026
Fundamentals as of Jul 30, 2026
52W Range
$22–$46
47% of range
Analyst Rating
BUY
16 analysts
Price Target
$46
+37% upside
P/E (TTM)
-6075.0
ROE
-32.2%
Net Profit Margin
-764.0%

About Agios Pharmaceuticals, Inc. - Common Stock Company overview from Wikipedia

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Read more

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 (or 2007) by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

History

In 2012, Agios was named among the defendants in a lawsuit against one of its founders, Craig Thompson, alleging that Thompson used research illegally taken from the Abramson Family Cancer Research Institute in research at Agios.

In May 2016, the company announced it would launch partnership with Celgene, developing metabolic immuno-oncology therapies and licensing AG-221 as well as AG-881 to Celgene, potentially garnering Agios $120 million in drug licensing payments.

In April 2017, the company raised $250 million in a new stock offering in anticipation of approval for its first cancer drug, enasidenib, by the US Food and Drug Administration.

In December 2017, the company filed a New Drug Application with the US FDA for ivosidenib for the treatment of adult patients with relapsed or refractory acute myeloid leukemia with an IDH1 mutation.

In November 2019, Agios announced an underwritten public offering of 8,250,000 shares of common stock at a price of $31.00 per share which would result in approximately $256 million aggregate gross proceeds.

In April 2022, the FDA approved mitapivat as first disease-modifying therapy for hemolytic anemia in adults with pyruvate kinase deficiency.

Corporate governance

As of August 2022, Agios' CEO is Brian Goff.

Agios was established as a private company and converted to a public company with its initial public offering in July 2013 and subsequent listing on NASDAQ.

== References ==

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

AGIO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$33.46
Market Cap
$2.53T
P/E (TTM)
-6075.0
EPS (TTM)
$-7.12
Revenue (TTM)
$54M
Div Yield
—
ROE
-32.2%
Debt/Equity
—
52W Range
$22 – $46

AGIO Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $54M
10-point trend, -22.7%
2016-12-31 → 2025-12-31
EPS $-7.12
7-point trend, -3.8%
2019-12-31 → 2025-12-31
Free Cash Flow $-377M
10-point trend, -1417.0%
2016-12-31 → 2025-12-31
Margins -764.0%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
AGIO
Peer Median
P/E (TTM)
5-point trend, -408.8%
-6075.0
27.2
P/S (TTM)
5-point trend, +6.3%
46793.6
25.4
P/B
5-point trend, -3.5%
2119.0
5.1
Price / FCF
5-point trend, +2.5%
-6700.8
—

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
AGIO
Peer Median
Operating Margin
5-point trend, -461.6%
-873.9%
—
Net Profit Margin
5-point trend, -374.2%
-764.0%
-473.7%
ROA
5-point trend, -119.9%
-27.9%
-40.2%
ROE
5-point trend, -127.0%
-32.2%
-50.4%
ROIC
5-point trend, +53.8%
-39.5%
—

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
AGIO
Peer Median
Current Ratio
5-point trend, -35.6%
11.5
9.0
Quick Ratio
5-point trend, -68.1%
1.1
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
AGIO
Peer Median
Revenue YoY
5-point trend, +54028000.00
48.0%
—
Revenue CAGR 3Y
5-point trend, +54028000.00
56.0%
—

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
AGIO
Peer Median
EPS (Diluted)
5-point trend, -126.8%
$-7.12
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
AGIO
Peer Median

AGIO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 16 analysts
  • Strong Buy 5 31.2%
  • Buy 7 43.8%
  • Hold 4 25.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

8 analysts · 2026-08-16
Median target $42.50 +27.0%
Mean target $45.75 +36.7%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.10%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-1.69 $-1.70 0.01%
March 31, 2026 $-1.69 $-1.84 0.15%
Dec. 31, 2025 $-1.86 $-1.99 0.13%
Sept. 30, 2025 $-1.78 $-1.94 0.16%
June 30, 2025 $-1.93 $-1.84 -0.09%
March 31, 2025 $-1.55 $-1.82 0.27%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
AGIO $1.59B -3.8 48.0% -764.0% -32.2% —
ADMA $4.34B 30.4 19.6% 28.8% 33.6% 57.4%
VRDN $3.17B -7.7 23359.9% -483.6% -55.4% —
STOK $1.87B -264.5 404.5% -3.7% -2.0% —
ZBIO $1.98B -4.3 100.0% -3777.4% -156.8% —
TSHA $1.57B -16.2 17.3% -1115.3% -44.0% —
GENB — — — — — —
DMRA — — 38.3% -17981.1% -167.0% —
SRPT $2.26B -3.0 15.6% -32.5% -57.1% —
SNDX $1.84B -6.4 627.8% -165.6% -257.1% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, -17.3% $54M $36M $27M $14M $0 $0 $118M $94M $43M $70M $59M $65M
Cost of Revenue 10-point trend, +6345000.00 $6M $4M $3M $2M $0 $0 $1M $1M $0 $0 · ·
R&D Expense 12-point trend, +238.3% $340M $301M $296M $280M $257M $221M $214M $341M $293M $220M $142M $100M
SG&A Expense 12-point trend, +842.9% $180M $157M $120M $122M $121M $115M $102M $114M $71M $51M $36M $19M
Operating Expenses 12-point trend, +340.3% $526M $462M $418M $403M $378M $336M $316M $457M $364M $271M $178M $119M
Operating Income 12-point trend, -772.2% $-472M $-426M $-391M $-389M $-378M $-336M $-316M $-362M $-321M $-201M $-119M $-54M
Interest Income 9-point trend, +6202.0% · · · $13M $836.0K $7M $15M $16M $6M $3M $968.0K $203.0K
Other Non-op 7-point trend, +1956000.00 $2M $6M $6M $7M $14M $0 $0 · · · · ·
Pretax Income 12-point trend, -667.3% $-414M $718M $-352M $-232M $-357M $-329M $-301M $-346M $-315M $-198M $-118M $-54M
Income Tax 10-point trend, -138.5% $-1M $44M $0 $0 · · $0 $0 $0 $0 $0 $-426.0K
Net Income 12-point trend, -671.5% $-413M $674M $-352M $-232M $1.60B $-327M $-411M $-346M $-315M $-198M $-118M $-54M
EPS (Basic) 7-point trend, -3.8% $-7.12 $11.86 $-6.33 $-4.23 $26.55 $-4.74 $-6.86 · · · · ·
EPS (Diluted) 7-point trend, -3.8% $-7.12 $11.64 $-6.33 $-4.23 $26.55 $-4.74 $-6.86 · · · · ·
Shares (Basic) 7-point trend, -3.4% 57,972,004 56,807,415 55,651,487 54,789,435 60,447,346 68,997,879 59,994,539 · · · · ·
Shares (Diluted) 7-point trend, -3.4% 57,972,004 57,889,255 55,651,487 54,789,435 60,447,346 68,997,879 59,994,539 · · · · ·
EBITDA 12-point trend, -772.2% $-472M $-426M $-391M $-389M $-378M $-316M $-418M $-362M $-321M $-201M $-119M $-54M
Balance Sheet 22
Annual Balance Sheet data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +535.2% $89M $76M $88M $139M $203M $127M $81M $71M $103M $161M $72M $14M
Short-term Investments 3-point trend, +35.3% · · · · · · · $515M $321M $381M · ·
Inventory 9-point trend, +32920000.00 $33M $28M $19M $8M $0 $15M $7M $869.0K $0 · · ·
Prepaid Expense 12-point trend, +816.7% $44M $40M $35M $39M $40M $16M $24M $17M $18M $10M $9M $5M
Current Assets 12-point trend, +162.0% $942M $966M $834M $833M $1.06B $637M $612M $614M $445M $560M $337M $360M
PP&E (Net) 12-point trend, +68.7% $11M $12M $15M $23M $29M $31M $31M $24M $24M $25M $23M $6M
PP&E (Gross) 12-point trend, +493.5% $71M $68M $68M $73M $74M $72M $64M $50M $44M $39M $31M $12M
Accum. Depreciation 12-point trend, +981.6% $60M $56M $52M $50M $45M $41M $32M $26M $19M $13M $8M $6M
Other Non-current Assets 12-point trend, +566.3% $4M $5M $4M $4M $3M $0 $0 $238.0K $891.0K $2M $611.0K $590.0K
Total Assets 12-point trend, +163.7% $1.30B $1.66B $937M $1.24B $1.44B $853M $891M $858M $614M $619M $420M $492M
Accounts Payable 12-point trend, +65.9% $18M $17M $10M $19M $17M $18M $22M $18M $23M $17M $15M $11M
Accrued Liabilities 12-point trend, +224.2% $45M $47M $43M $30M $32M $31M $53M $42M $34M $32M $16M $14M
Current Liabilities 12-point trend, +34.6% $82M $81M $68M $63M $60M $94M $93M $94M $95M $88M $53M $61M
Capital Leases 7-point trend, -79.4% $22M $40M $57M $72M $86M $97M $106M · · · · ·
Other Non-current Liabilities 5-point trend, +90000.00 $90.0K $880.0K $1M $3M $0 · · · · · · ·
Total Liabilities 10-point trend, -60.0% $104M $122M $126M $138M $146M $453M $250M $171M $239M $261M · ·
Common Stock 8-point trend, +91.9% · · · · $71.0K $69.0K $68.0K $58.0K $49.0K $42.0K $38.0K $37.0K
Retained Earnings 12-point trend, -236.5% $-562M $-149M $-823M $-471M $-239M $-1.84B $-1.52B $-1.10B $-798M $-483M $-285M $-167M
Treasury Stock 6-point trend, +802486000.00 $802M $802M $802M $802M $802M $0 · · · · · ·
Stockholders' Equity 12-point trend, +181.2% $1.19B $1.54B $811M $1.10B $1.29B $400M $641M $688M $376M $359M $345M $424M
Liabilities + Equity 12-point trend, +163.7% $1.30B $1.66B $937M $1.24B $1.44B $853M $891M $858M $614M $619M $420M $492M
Shares Outstanding 12-point trend, +57.5% 58,448,592 73,372,696,000 72,161,489 71,256,118 70,550,631 69,293,920 68,401,105 58,218,653 48,826,153 42,220,444 37,696,502 37,100,513
Cash Flow 13
Annual Cash Flow data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
D&A 3-point trend, +25.7% · · · · · · $8M $7M $6M · · ·
Stock-based Comp 12-point trend, +356.7% $53M $43M $45M $49M $54M $62M $58M $73M $48M $42M $32M $12M
Deferred Tax Flat — no change across 3 periods · · · · · · · · · $0 $0 $0
Other Non-cash · · · · · · $-40M · · · · ·
Operating Cash Flow 12-point trend, -528.4% $-373M $-390M $-296M $-309M $-407M $-291M $-371M $-304M $-285M $39M $-77M $-59M
CapEx 12-point trend, +94.8% $4M $2M $999.0K $5M $6M $14M $12M $7M $5M $10M $20M $2M
Investing Cash Flow 11-point trend, +194.0% $377M $363M $240M $243M $1.25B $76M $91M $-274M $-58M $-119M $128M ·
Stock Issued 8-point trend, -100.0% · · · · $0 $0 $277M $516M $270M $162M $0 $334M
Net Stock Activity 7-point trend, -100.0% · · · · $0 $0 $277M $516M $270M $162M · $334M
Financing Cash Flow 11-point trend, +36.1% $9M $14M $5M $2M $-766M $262M $290M $546M $285M $170M $6M ·
Net Change in Cash 12-point trend, +122.4% $13M $-12M $-51M $-64M $76M $47M $10M $-32M $-58M $89M $58M $-58M
Taxes Paid 3-point trend, -60.0% $628.0K $43M $2M · · · · · · · · ·
Free Cash Flow 12-point trend, -512.8% $-377M $-392M $-297M $-314M $-413M $-306M $-383M $-311M $-290M $29M $-97M $-62M
Profitability 7
Annual Profitability data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 8-point trend, -955.0% -873.9% -1166.5% -1459.5% -2732.1% · -155.6% -361.6% · -745.8% · · -82.8%
Net Margin 8-point trend, -833.3% -764.0% 1845.9% -1312.6% -1627.8% · -161.1% -349.0% · -731.6% · · -81.9%
Pretax Margin 8-point trend, -828.2% -765.9% 1967.2% -1312.6% -1627.8% · -161.2% -349.0% · -731.6% · · -82.5%
EBITDA Margin 8-point trend, -955.0% -873.9% -1166.5% -1459.5% -2732.1% · -155.6% -354.7% · -745.8% · · -82.8%
ROA 12-point trend, -80.6% -27.9% 51.8% -32.4% -17.3% 140.1% -37.5% -47.0% -47.0% -51.0% -38.2% -25.8% -15.4%
ROE 12-point trend, -67.3% -32.2% 42.5% -41.5% -21.6% 119.4% -74.4% -75.6% -47.8% -85.7% -56.4% -30.6% -19.2%
ROIC 6-point trend, -211.8% -39.5% -25.9% · · · · -66.6% -52.7% -85.4% · · -12.7%
Liquidity & Solvency 2
Annual Liquidity & Solvency data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, +94.7% 11.5 11.9 12.3 13.3 17.8 6.7 6.6 6.6 4.7 6.3 6.4 5.9
Quick Ratio 12-point trend, +372.0% 1.1 0.9 1.3 2.2 3.4 1.4 0.9 6.3 4.5 1.8 1.4 0.2
Efficiency 2
Annual Efficiency data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 8-point trend, -80.6% 0.0 0.0 0.0 0.0 · 0.2 0.1 · 0.1 · · 0.2
Inventory Turnover 7-point trend, -93.5% 0.2 0.2 0.2 0.4 · 0.3 0.3 3.2 · · · ·
Per Share 5
Annual Per Share data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, +78.5% $20.41 $26.96 $14.50 $20.00 $23.78 $5.77 $9.36 $11.81 $7.69 $8.49 $9.16 $11.44
Revenue / Share 4-point trend, +258.6% $0.93 $0.63 $0.48 $0.26 · · · · · · · ·
Cash Flow / Share 5-point trend, +4.5% $-6.43 $-6.73 $-5.32 $-5.65 $-6.74 · · · · · · ·
Cash / Share 12-point trend, +303.2% $1.52 $1.33 $1.58 $2.53 $3.74 $1.84 $1.18 $1.21 $2.10 $3.81 $1.90 $0.38
EPS (TTM) 8-point trend, -347.8% $-7.12 $11.64 $-6.33 $-4.23 $26.55 $-4.74 $-6.86 · · · · $-1.59
Growth Rates 4
Annual Growth Rates data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 3-point trend, -45.6% 48.0% 36.1% 88.4% · · · · · · · · ·
Revenue CAGR 3Y 56.0% · · · · · · · · · · ·
EPS CAGR 3Y · -24.0% · · · · · · · · · ·
Net Income CAGR 3Y · -25.1% · · · · · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for AGIO
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -17.3% $54M $36M $27M $14M $0 $0 $118M $94M $43M $70M $59M $65M
Net Income TTM 12-point trend, -671.5% $-413M $674M $-352M $-232M $1.60B $-327M $-411M $-346M $-315M $-198M $-118M $-54M
Market Cap 12-point trend, -61.7% $1.59B $1.88B $1.25B $1.55B $1.79B $3.00B $3.27B $2.68B $2.79B $1.76B $2.45B $4.16B
P/E 8-point trend, +94.6% -3.8 2.8 -3.5 -6.6 1.2 -9.1 -7.0 · · · · -70.5
P/S 10-point trend, -53.7% 29.4 51.5 46.4 108.5 · · 27.7 28.4 64.9 25.2 41.4 63.6
P/B 12-point trend, -86.4% 1.3 1.2 1.5 1.4 1.4 7.5 5.1 3.9 7.4 4.9 7.1 9.8
P / Tangible Book 6-point trend, -82.3% 1.3 1.2 1.5 1.4 1.4 7.5 · · · · · ·
P / Cash Flow 12-point trend, +93.9% -4.3 -4.8 -4.2 -5.0 -4.4 -10.3 -8.8 -8.8 -9.8 45.7 -31.8 -70.0
P / FCF 12-point trend, +93.8% -4.2 -4.8 -4.2 -4.9 -4.3 -9.8 -8.5 -8.6 -9.6 61.5 -25.2 -67.5
Earnings Yield 8-point trend, -1742.3% -26.2% 35.4% -28.4% -15.1% 80.8% -10.9% -14.4% · · · · -1.4%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $54M$36M$27M$14M$0
Operating Margin % -873.9%-1166.5%-1459.5%-2732.1%—
Net Income $-413M$674M$-352M$-232M$1.60B
Diluted EPS $-7.12$11.64$-6.33$-4.23$26.55
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 11.511.912.313.317.8
Quick Ratio 1.10.91.32.23.4
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-377M$-392M$-297M$-314M$-413M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 264 filers · $2.0B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
46 (+12 vs prior Q) 30 (-3 vs prior Q) 95 (+17 vs prior Q) 62 (-27 vs prior Q) +12.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FARALLON CAPITAL MANAGEMENT, L.L.C. $219,594,714 5,917,400 11.17% Shares
STATE STREET CORP $131,144,972 3,533,633 6.67% Shares
Lynx1 Capital Management LP $126,505,652 3,408,937 6.43% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $107,552,091 2,898,197 5.47% Shares
ARMISTICE CAPITAL, LLC $104,279,100 2,810,000 5.30% Call option
VANGUARD CAPITAL MANAGEMENT LLC $99,523,268 2,681,845 5.06% Shares
ARMISTICE CAPITAL, LLC $89,064,000 2,400,000 4.53% Shares
Erste Asset Management GmbH $81,972,396 2,154,900 4.17% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $78,332,000 2,110,809 3.98% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $51,046,957 1,375,558 2.60% Shares
GEODE CAPITAL MANAGEMENT, LLC $50,151,466 1,351,093 2.55% Shares
ADAR1 Capital Management, LLC $47,799,647 1,288,053 2.43% Shares
DIMENSIONAL FUND ADVISORS LP $44,225,805 1,191,749 2.25% Shares
GOLDMAN SACHS GROUP INC $36,642,971 987,415 1.86% Shares
D. E. Shaw & Co., Inc. $34,087,168 918,544 1.73% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $30,078,768 810,530 1.53% Shares
Foresite Capital Management VI LLC $29,131,350 785,000 1.48% Shares
CITADEL ADVISORS LLC $26,154,683 704,788 1.33% Shares
Parkman Healthcare Partners LLC $24,828,297 669,046 1.26% Shares
SCS Capital Management LLC $22,742,864 612,850 1.16% Shares
Qube Research & Technologies Ltd $22,178,346 597,638 1.13% Shares
Defilade Capital Management, L.P. $20,293,529 546,848 1.03% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19,969,930 538,128 1.02% Shares
TWO SIGMA INVESTMENTS, LP $19,905,062 536,380 1.01% Shares
Rock Springs Capital Management LP $19,763,413 532,563 1.01% Shares
Schonfeld Strategic Advisors LLC $19,300,279 520,083 0.98% Shares
Point72 Asset Management, L.P. $18,790,426 506,344 0.96% Shares
JANE STREET GROUP, LLC $18,280,312 492,598 0.93% Shares
VANGUARD FIDUCIARY TRUST CO $14,690,661 395,868 0.75% Shares
PANAGORA ASSET MANAGEMENT INC $13,876,579 373,931 0.71% Shares
KENNEDY CAPITAL MANAGEMENT LLC $13,850,565 373,230 0.70% Shares
Connor, Clark & Lunn Investment Management Ltd. $13,342,901 359,550 0.68% Shares
Squarepoint Ops LLC $11,917,431 321,138 0.61% Shares
JPMORGAN CHASE & CO $11,853,074 309,008 0.60% Shares
Ensign Peak Advisors, Inc $11,045,049 297,630 0.56% Shares
BNP PARIBAS FINANCIAL MARKETS $9,996,803 269,383 0.51% Shares
ALGERT GLOBAL LLC $9,203,540 248,007 0.47% Shares
JANE STREET GROUP, LLC $7,974,939 214,900 0.41% Put option
Palo Alto Investors LP $7,926,733 213,601 0.40% Shares
Tetragon Partners GP Ltd $7,629,037 205,579 0.39% Shares
AXA Investment Managers S.A. $7,131,875 177,675 0.36% Shares
Cutter Capital Management, LP $6,895,755 235,350 0.35% Shares
BlackRock, Inc. $6,545,388 176,378 0.33% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $6,334,677 170,700 0.32% Call option
BNP PARIBAS ASSET MANAGEMENT Holding S.A. $6,306,139 169,931 0.32% Shares
FIRST TRUST ADVISORS LP $6,144,933 165,587 0.31% Shares
Ishara Investments LP $6,086,040 164,000 0.31% Shares
GROUP ONE TRADING LLC $5,640,497 151,994 0.29% Shares
BOOTHBAY FUND MANAGEMENT, LLC $5,562,269 149,886 0.28% Shares
BANK OF AMERICA CORP /DE/ $5,505,083 148,345 0.28% Shares
MARSHALL WACE, LLP $5,150,868 138,800 0.26% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5,080,359 136,900 0.26% Put option
AMERICAN CENTURY COMPANIES INC $4,991,740 134,512 0.25% Shares
Man Group plc $4,617,931 124,439 0.23% Shares
ArrowMark Colorado Holdings LLC $4,368,367 117,714 0.22% Shares
Pictet Asset Management Holding SA $4,247,606 111,861 0.22% Shares
Swiss National Bank $4,143,703 111,660 0.21% Shares
CAPITAL FUND MANAGEMENT S.A. $3,862,408 104,080 0.20% Shares
Assenagon Asset Management S.A. $3,857,770 103,955 0.20% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $3,700,831 99,726 0.19% Shares
Knott David M Jr $3,527,602 95,058 0.18% Shares
Trexquant Investment LP $3,471,232 93,539 0.18% Shares
CITADEL ADVISORS LLC $3,402,987 91,700 0.17% Call option
Jain Global LLC $3,401,020 91,647 0.17% Shares
Caligan Partners LP $3,339,900 90,000 0.17% Call option
CITADEL ADVISORS LLC $3,295,368 88,800 0.17% Put option
CITIGROUP INC $3,182,331 85,754 0.16% Shares
RHUMBLINE ADVISERS $2,948,045 79,441 0.15% Shares
Bank of New York Mellon Corp $2,916,846 78,600 0.15% Shares
Campbell & CO Investment Adviser LLC $2,712,555 73,095 0.14% Shares
Exome Asset Management LLC $2,616,255 70,500 0.13% Shares
Edgestream Partners, L.P. $2,604,936 70,195 0.13% Shares
TUDOR INVESTMENT CORP ET AL $2,441,059 65,779 0.12% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $2,319,520 68,564 0.12% Shares
TWO SIGMA ADVISERS, LP $2,319,144 85,200 0.12% Shares
ALPS ADVISORS INC $2,228,789 60,059 0.11% Shares
Seven Fleet Capital Management LP $2,111,559 56,900 0.11% Shares
ALLIANCEBERNSTEIN L.P. $2,092,859 61,864 0.11% Shares
Rafferty Asset Management, LLC $2,062,574 55,580 0.10% Shares
Engineers Gate Manager LP $2,000,674 53,912 0.10% Shares
WELLS FARGO & COMPANY/MN $1,935,843 52,165 0.10% Shares
VANGUARD ASSET MANAGEMENT, Ltd $1,931,576 52,050 0.10% Shares
XTX Topco Ltd $1,869,082 50,366 0.10% Shares
Caption Management, LLC $1,855,500 50,000 0.09% Call option
Tetragon Partners GP Ltd $1,855,500 50,000 0.09% Call option
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main $1,846,742 49,764 0.09% Shares
BARCLAYS PLC $1,725,651 46,501 0.09% Shares
Quantinno Capital Management LP $1,614,805 43,514 0.08% Shares
MARTINGALE ASSET MANAGEMENT L P $1,596,064 43,009 0.08% Shares
IEQ CAPITAL, LLC $1,499,392 40,404 0.08% Shares
Kodai Capital Management LP $1,485,276 50,692 0.08% Shares
Virtus Investment Advisers, LLC $1,464,843 39,473 0.07% Shares
Caption Management, LLC $1,456,530 39,249 0.07% Shares
JANE STREET GROUP, LLC $1,451,001 39,100 0.07% Call option
FMR LLC $1,446,325 38,974 0.07% Shares
Aquatic Capital Management LLC $1,433,448 38,627 0.07% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $1,400,049 37,727 0.07% Shares
VANGUARD GROUP INC $1,308,928 48,087 0.07% Shares
EDGEWOOD MANAGEMENT LLC $1,298,850 35,000 0.07% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1,298,776 34,998 0.07% Shares

Company insiders 33 insiders · 12 officers · 19 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Brian Goff Chief Executive Officer June 18, 2026 A — 0 0 $0
Cecilia Jones Chief Financial Officer June 18, 2026 A — 0 0 $0
Andrew Hirsch Chief Financial Officer April 22, 2019 A 12,374 0 0 $0
John Duncan Higgons Chief Operating Officer Jan. 4, 2016 M 120,834 0 0 $0
Krishnan Viswanadhan Chief Strategy and Operations June 18, 2026 A — 0 0 $0
Tsveta Milanova Chief Commercial Officer June 18, 2026 A — 0 0 $0
James William Burns Chief Legal Officer June 18, 2026 A — 0 0 $0
Scott Biller Chief Scientific Officer April 5, 2019 M 26,511 0 0 $0
Christopher Bowden Chief Medical Officer April 1, 2019 M 7,238 0 0 $0
Steven L. Hoerter Chief Commercial Officer March 4, 2019 M 10,941 0 0 $0
Carman Alenson Principal Accounting Officer Feb. 22, 2019 A 2,796 0 0 $0
Glenn Goddard Senior Vice President, Finance Feb. 16, 2016 A 0 0 0 $0
Adams Catherine Owen Director June 18, 2026 A 10,865 0 0 $0
Rahul D. Ballal Director June 18, 2026 A 15,230 0 0 $0
David Scadden Director June 18, 2026 A 20,419 0 0 $0
Maykin Ho Director June 18, 2026 A 19,848 0 0 $0
Cynthia Smith Director June 18, 2026 A 15,230 0 0 $0
Jacqualyn A Fouse Director June 18, 2026 A 154,156 0 0 $0
Kaye I Foster-Cheek Director June 18, 2026 A 10,284 0 0 $0
Jeffrey D Capello Director June 18, 2026 A 10,865 0 0 $0
Paul J Clancy Director May 31, 2019 M 1,400 0 0 $0
Ian T Clark Director May 31, 2019 M 1,400 0 0 $0
John Maraganore Director May 31, 2019 M 37,609 0 0 $0
David P Schenkein Director Feb. 22, 2019 A 89,503 0 0 $0
Lewis Clayton Cantley Jr. Director Dec. 7, 2017 S 79,515 0 0 $0
Robert Nelsen Director March 6, 2017 S 0 0 0 $0
Douglas G. Cole Director Aug. 10, 2016 J 2,778 0 0 $0
Marc Tessier-Lavigne Director June 21, 2016 A 101,009 0 0 $0
Perry A Karsen Director June 23, 2015 A — 0 0 $0
Kevin P Starr Director Feb. 19, 2015 J 184,386 0 0 $0
Celgene European Investment Co LLC 10% owner Dec. 16, 2014 P 1,231,778 0 0 $0
Sarah Gheuens — Aug. 4, 2026 S 54,645 0 2 $-1,064,903
Jay T. Backstrom — July 8, 2026 M 1,447 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 3 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
BRISTOL-MYERS SQUIBB COMPANY, CELGENE CORPORATION, CELGENE SWITZERLAND LLC, CELGENE EUROPEAN INVESTMENT COMPANY LLC, CELGENE ALPINE INVESTMENT CO., LLC April 5, 2021 — Initial filing — SEC
CELGENE SWITZERLAND LLC, CELGENE EUROPEAN INVESTMENT COMPANY LLC, CELGENE ALPINE INVESTMENT CO., LLC, CELGENE CORPORATION ×3 filings Nov. 14, 2019 — Initial filing Capital structure SEC
CELGENE EUROPEAN INVESTMENT COMPANY LLC, CELGENE ALPINE INVESTMENT CO., LLC, CELGENE CORPORATION ×3 filings Dec. 17, 2014 — Initial filing — SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 57 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBP · ETFis Series Trust I 1.64% 34,703 NS April 30, 2026 N-PORT
SBIO · ALPS ETF Trust 1.10% 60,392 NS May 31, 2026 N-PORT
HAPS · Harbor ETF Trust 0.77% 43,269 NS April 30, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.60% 110,585 NS April 30, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.54% 3,805 SH Aug. 8, 2026 Daily
AGNG · Global X Funds 0.28% 7,695 NS May 31, 2026 N-PORT
FYC · First Trust Exchange-Traded AlphaDE… 0.27% 101,599 NS April 30, 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0.19% 17,290 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.14% 408,719 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.13% 3,239 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.13% 48,730 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.13% 113,617 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.12% 109,727 NS May 31, 2026 N-PORT
IWN · iShares Trust 0.11% 515,162 SH Aug. 8, 2026 Daily
FYX · First Trust Exchange-Traded AlphaDE… 0.09% 40,934 NS April 30, 2026 N-PORT
BIB · ProShares Trust 0.09% 2,166 NS May 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.08% 22,172 NS April 30, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.07% 340,226 SH Aug. 8, 2026 Daily
VBK · VANGUARD INDEX FUNDS 0.06% 788,655 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.06% 1,508,427 SH Aug. 8, 2026 Daily
FAD · First Trust Exchange-Traded AlphaDE… 0.06% 9,472 NS April 30, 2026 N-PORT
ESML · iShares Trust 0.05% 48,207 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.05% 24,449 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.04% 2,658 NS May 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.04% 193,306 NS April 30, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.04% 280,734 NS May 31, 2026 N-PORT
ISCG · iShares Trust 0.03% 10,195 SH Aug. 8, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.03% 1,364,364 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 167,169 SH Aug. 8, 2026 Daily
ISCB · iShares Trust 0.03% 2,463 SH Aug. 8, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.02% 25,231 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.02% 2,079 NS May 31, 2026 N-PORT
ISCV · iShares Trust 0.02% 5,020 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.02% 683,802 SH Aug. 8, 2026 Daily
DXUV · Dimensional ETF Trust 0.02% 2,762 NS April 30, 2026 N-PORT
URTY · ProShares Trust 0.02% 2,105 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.02% 5,903 NS May 31, 2026 N-PORT
WSML · iShares Trust 0.02% 3,329 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 3,639 SH Aug. 8, 2026 Daily
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 2,328 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.01% 136,570 NS April 30, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.01% 8,867 NS April 30, 2026 N-PORT
HDG · ProShares Trust 0.01% 53 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.01% 25,095 NS May 31, 2026 N-PORT
IWO · iShares Trust 0.01% 30,958 SH Aug. 8, 2026 Daily
AVSU · AMERICAN CENTURY ETF TRUST 0.01% 1,068 NS May 31, 2026 N-PORT
TILT · FlexShares Trust 0.01% 4,329 NS April 30, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 17,627 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 19,324 NS April 30, 2026 N-PORT
IWV · iShares Trust 0.00% 16,536 SH Aug. 8, 2026 Daily