Eve Elizabeth Slater

Insider

First SEC filing: June 4, 2007 · Latest: June 4, 2007

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Insider at

0 buys (P) 0 sells (S) Net: $0 + 9 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

9 other filings hidden

Date	Ticker	Code	Shares	Price	Value	Owned after	Δ own	A/D	vs now
June 1, 2007	VRTX	A	20,000	—	—	20,000 Direct	—	Acquired	(price as of 2026-08-21)
May 29, 2007	VRTX	M	10,000	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-21)
May 29, 2007	VRTX	S	10,000	$30.42	$304,200	1,105 Direct	-90.05%	Disposed	1697.9% (price as of 2026-08-21)
May 29, 2007	VRTX	M	10,000	$13.32	$133,200	11,105 Direct	+904.98%	Acquired	4006.0% (price as of 2026-08-21)
April 25, 2007	INVA	A	15,000	—	—	15,000 Direct	—	Acquired	(price as of 2026-08-21)
June 1, 2006	VRTX	A	20,000	—	—	57,500 Direct	+53.33%	Acquired	(price as of 2026-08-21)
May 17, 2006	VRTX	P	455	$31.98	$14,551	1,105 Direct	+70.00%	Acquired	1610.2% (price as of 2026-08-21)
April 26, 2006	INVA	A	12,903	—	—	12,903 Direct	—	Acquired	(price as of 2026-08-21)
March 23, 2006	VRTX	P	650	$36.00	$23,400	650 Direct	—	Acquired	1419.2% (price as of 2026-08-21)
Dec. 8, 2005	INVA	A	25,806	—	—	25,806 Direct	—	Acquired	(price as of 2026-08-21)
June 1, 2005	VRTX	A	10,000	—	—	37,500 Direct	+36.36%	Acquired	(price as of 2026-08-21)
June 1, 2004	VRTX	A	7,500	—	—	27,500 Direct	+37.50%	Acquired	(price as of 2026-08-21)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Options, RSUs and convertible securities reported on Form 4 Table II.

Date	Ticker	Security	Underlying	Exercise price	Expiration	Shares	A/D
June 1, 2007	VRTX	Stock Option	Common Stock (20,000)	$29.84	May 31, 2017	20,000	Acquired
May 29, 2007	VRTX	Stock Option	Common Stock (10,000)	$13.32	May 31, 2015	10,000	Disposed
April 25, 2007	INVA	Stock Option (Right to Buy)	Common Stock (15,000)	$33.25	April 24, 2017	15,000	Acquired
June 1, 2006	VRTX	Stock Option	Common Stock (20,000)	$34.32	May 31, 2016	20,000	Acquired
April 26, 2006	INVA	Stock Option (Right to Buy)	Common Stock (12,903)	$27.56	April 25, 2016	12,903	Acquired
Dec. 8, 2005	INVA	Stock Option (right to buy)	Common Stock (25,806)	$21.02	Dec. 7, 2015	25,806	Acquired
June 1, 2005	VRTX	Stock Option	Common Stock (10,000)	$13.32	May 31, 2015	10,000	Acquired
June 1, 2004	VRTX	Stock Option	Common Stock (7,500)	$9.09	May 31, 2014	7,500	Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Securities held when first becoming an insider, per SEC Form 3.

Date	Ticker	Security	Shares	Ownership
May 10, 2004	VRTX	Stock Option [F1]→ Common Stock (20,000)	20,000	Direct