INVA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $20.50
Market Cap (MRQ) $1.49B
P/E (TTM) 4.7
EPS (TTM) $4.35
Revenue (TTM) $440M
ROE (TTM) 36.7%
Debt/Equity (MRQ) 0.2
52W Range $17–$25

INVA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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Stock splits 1
Ex-date Split Type
June 3, 2014 1241-for-1000 Forward

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$411M
2016-12-31 → 2025-12-31
EPS$3.30
2016-12-31 → 2025-12-31
Free Cash Flow·
2016-12-31 → 2021-12-31
Net margin81.2%
2017-12-31 → 2021-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend INVA 5Y avg Peer Median Verdict
P/E (TTM) 4.75Y avg ≈14.6 ≈14.6 12.9 Undervalued
P/S (TTM) 3.4 · 6.9 Undervalued
P/B (MRQ) 1.2 · 3.9 Undervalued
Price / FCF (TTM) 7.9 · · ·
Price / Cash Flow (TTM) 7.8 · 26.5 Undervalued
Price / Tangible Book (MRQ) 1.45Y avg ≈2.3 ≈2.3 · ·
PEG Ratio ≈0.5 · · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Dividends Yield, payout ratio, dividend history, 5Y CAGR

13
Annualized Payout≈$1.00Paid quarterly
Ex-dateAmountCurrencyYield
Sep 8, 2015$0.25USD≈7.4%
Jun 10, 2015$0.25USD≈5.5%
Mar 10, 2015$0.25USD≈3.8%
Nov 21, 2014$0.25USD≈3.6%
Aug 26, 2014$0.25USD≈1.1%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -67.1%
Next Report Nov 03, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 4, 2026 $-1.14 $0.44 -356.4%
March 31, 2026 May 13, 2026 $-0.05 $0.40 -112.6%
Dec. 31, 2025 $1.94 $0.56 245.8%
Sept. 30, 2025 $1.08 $0.49 119.4%
June 30, 2025 $0.77 $0.51 51.0%
March 31, 2025 $-0.74 $0.30 -350.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 17
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $411M$359M$310M$331M$392M$337M$261M$261M$217M$134M$54M$8M
Gross Profit $308M$296M$246M·········
R&D Expense $31M$14M$34M$41M$576.0K$2M$0$0$1M$1M$3M$7M
SG&A Expense $113M$116M$98M$64M$16M$14M$15M$20M$32M$23M$20M$35M
Operating Expenses $144M$129M$132M$44M$-53M$-17M$15M$23M$34M$25M$22M$42M
Operating Income $164M$167M$114M·$375M$321M$246M$238M$184M$109M$32M$-34M
Interest Expense $17M$22M$19M$16M$19M$18M$19M$24M$44M$52M$52M$37M
Interest Income $21M$19M$16M$6M$2M$2M$6M·····
Other Non-op $-3M$-3M$-5M$-3M$-4M$-348.0K$-345.0K$-6M$-7M$2M$1M$-3M
Pretax Income $327M$37M$194M$287M$445M$354M$233M$210M$134M$60M$-19M$-74M
Income Tax $56M$14M$14M$67M$76M$60M$42M$-196M$4.0K$95.0K$0$0
Net Income $271M$23M$180M$220M$369M$294M$191M$406M$134M$60M$-19M·
EPS (Basic) $4.02$0.37$2.75$3.07$3.24$2.21$1.55$3.92$1.25$0.54$-0.16$-1.50
EPS (Diluted) $3.30$0.36$2.20$2.37$2.87$2.02$1.43$3.53$1.17$0.53$-0.16$-1.50
Shares (Basic) 67,395,00062,726,00065,435,00069,644,00082,062,000101,320,000101,150,000100,849,000106,945,000110,280,000115,372,000112,059,000
Shares (Diluted) 84,760,00074,187,00086,876,00095,248,00094,310,000113,554,000113,409,000113,408,000119,866,000123,233,000115,372,000112,059,000
EBITDA ····$389M$335M·$252M$198M$123M$46M$-22M
Balance Sheet 28
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $551M$305M$194M$291M$202M$246M$278M$62M$73M$118M$159M$97M
Short-term Investments ····$0·······
Receivables ···········$0
Inventory $39M$34M$41M$56M$0······$0
Prepaid Expense $27M$21M$22M$30M$1M$2M$962.0K$849.0K$754.0K$766.0K$814.0K$1M
Other Current Assets $2M$656.0K$4M$3M$70.0K·······
Current Assets $728M$554M$344M$444M$314M$342M$431M$199M$200M$198M$214M$252M
PP&E (Net) $2M$514.0K$483.0K$170.0K$12.0K$28.0K$33.0K$160.0K$209.0K$368.0K$221.0K$324.0K
PP&E (Gross) ···········$324.0K
Accum. Depreciation ···········$0
Goodwill $18M$18M$18M$27M$0·······
Intangibles $182M$208M$230M$253M$0·······
Other Non-current Assets $41M$41M$3M$4M$11.0K$214.0K$312.0K$37.0K$37.0K$37.0K$18.0K$18M
Total Assets $1.64B$1.30B$1.24B$1.23B$926M$1000M$725M$548M$367M$379M$409M$522M
Accounts Payable $5M$2M$7M$3M$27.0K$66.0K$10.0K$11.0K$601.0K$128.0K$818.0K$0
Current Liabilities $50M$236M$38M$135M$6M$6M$5M$6M$35M$20M$13M$14M
Capital Leases $11M$1M$2M$2M$0··$0····
Deferred Tax $32M$0$563.0K$6M$0·······
Other Non-current Liabilities $66M$64M$72M$71M$0$106.0K$219.0K$586.0K$940.0K$1M$2M$2M
Long-term Debt ·········$716M$748M$726M
Total Debt ····$395M$386M·$383M$574M$716M··
Common Stock $747.0K$627.0K$633.0K$692.0K$696.0K$1M$1M$1M$1M$1M$1M$1M
Retained Earnings $269M$-2M$-25M$-205M$-456M$-722M$-946M$-1.10B$-1.50B$-1.63B$-1.69B$-1.67B
Treasury Stock ·$0$394M$394M$394M$0·$0$3M$3M$3M$3M
AOCI ·····$0$27.0K$-3.0K$-18.0K$1.0K$-2.0K$-87.0K
Stockholders' Equity $1.17B$691M$675M$566M$526M$608M$313M$154M$-243M$-353M$-343M$-223M
Liabilities + Equity $1.64B$1.30B$1.24B$1.23B$926M$1000M$725M$548M$367M$379M$409M$522M
Shares Outstanding 74,636,00062,665,00063,307,00069,188,00069,566,000101,392,000101,288,000101,098,000102,046,000108,585,000114,933,000116,445,000
Cash Flow 17
Metric Trend 202520242023202220212020201920182017201620152014
D&A ····$14M$14M$14M$14M$14M$14M$14M$12M
Stock-based Comp $9M$6M$6M$7M$2M$2M$2M$3M$10M$8M$7M$27M
Deferred Tax $44M$-13M$4M$25M$76M$60M$42M$-196M$0$0··
Amort. of Intangibles $26M$26M$22M$6M$0$0······
Other Non-cash ····$-97M$-57M·$-4M$-16M···
Operating Cash Flow $197M$189M$141M$202M$364M$313M$257M$224M$142M$61M$10M$-131M
CapEx $1M$270.0K$411.0K$67.0K$0$13.0K$12.0K$0$0$278.0K$7.0K$689.0K
Investing Cash Flow $40M$-64M$-67M$-57M$44M$-315M$-18M$4M$-23M$-5M$159M$-65M
Stock Issued $3M$1M$170.0K$370.0K$1M$436.0K$627.0K$1M$435.0K$385.0K$8M$55M
Stock Repurchased $5M$15M$76M$9M$394M$0$0$0$98M$78M$26M$0
Net Stock Activity ····$-393M$436.0K·$1M$-97M$-78M$-20M$49M
Dividends Paid ····$0$0$11.0K$80.0K$281.0K$960.0K$87M$57M
Financing Cash Flow $9M$-13M$-172M$-56M$-452M$-30M$-24M$-238M$-163M$-98M$-107M$149M
Net Change in Cash $246M$111M$-98M$90M$-45M$-32M$216M$-11M$-45M$-41M$62M$-47M
Taxes Paid $19M$12M$0$54M$0$0······
Free Cash Flow ····$364M$313M·$224M$142M$61M$10M$-131M
Levered FCF ····$348M$298M·$177M··$-42M·
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin ····95.7%95.3%·91.3%84.5%81.6%58.5%-402.3%
Net Margin ····94.1%87.2%·155.7%61.8%···
Pretax Margin ····113.6%105.2%·80.6%·44.6%-34.8%·
EBITDA Margin ····99.2%99.5%·96.6%91.0%92.0%84.4%-258.0%
ROA ····38.3%34.1%·88.8%36.0%···
ROE ····72.1%68.9%·-910.3%-45.1%···
ROIC ····38.4%28.8%·85.8%··-9.2%·
Liquidity & Solvency 5
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio ····54.056.0·34.95.89.915.918.3
Quick Ratio ····34.740.3·11.02.15.911.87.0
Debt / Equity ····1.00.7·2.5-2.4-2.0··
LT Debt / Equity ····1.00.7·2.5-2.4-2.0··
Interest Coverage ····19.717.5·9.94.22.10.6-0.9
Efficiency 2
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover ····0.40.4·0.60.60.30.10.0
Receivables Turnover ···········84.8
Per Share 6
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share ····$5.96$5.33·$1.52$-2.38$-3.25$-2.98·
Revenue / Share ····$4.16$2.97·$2.30$1.81$1.08··
Cash Flow / Share ····$3.86$2.76·$1.97$1.18$0.49··
Cash / Share ····$2.90$2.43·$0.62$0.72$1.09$1.39·
Dividend / Share ········$0.00$0.00$0.75$0.50
EPS (TTM) $3.30$0.36$2.20$2.37$2.87$2.02$1.43$3.53$1.17$0.53$-0.16$-1.50
Growth Rates 9
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 14.7%15.5%-6.3%-15.4%16.4%·······
Revenue CAGR 3Y 7.5%-2.9%-2.7%·········
Revenue CAGR 5Y 4.1%···········
EPS YoY 816.7%-83.6%-7.2%-17.4%42.1%·······
EPS CAGR 3Y 11.7%-49.9%2.9%·········
EPS CAGR 5Y 10.3%···········
Net Income YoY 1059.2%-87.0%-18.4%-40.3%25.5%·······
Net Income CAGR 3Y 7.2%-60.1%-15.1%·········
Net Income CAGR 5Y -1.6%···········
Valuation (TTM) 17
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $411M$359M$310M$331M$392M$337M$261M$261M$217M$134M$54M$8M
Net Income TTM $271M$23M$180M$220M$369M$294M$191M$406M$134M$60M$-19M·
Market Cap ····$1.20B$1.26B·$1.76B$1.45B$1.16B$1.21B·
Enterprise Value ····$1.39B$1.40B·$2.08B$1.95B$1.76B··
P/E 6.148.27.35.66.06.19.94.912.120.2-65.9-9.4
P/S ····3.13.7·6.86.78.722.5·
P/B ····2.92.3·11.5-6.0-3.3-3.5·
P / Tangible Book 1.52.32.43.22.32.1······
P / Cash Flow ····3.34.0·7.910.219.1119.6·
P / FCF ····3.34.0·7.910.219.1119.7·
EV / EBITDA ····3.64.2·8.39.914.3··
EV / FCF ····3.84.5·9.313.829.0··
EV / Revenue ····3.64.1·8.09.013.2··
Dividend Yield ····0.00%0.00%·0.00%0.02%0.08%7.2%·
Earnings Yield 16.5%2.1%13.7%17.9%16.6%16.3%10.1%20.2%8.2%5.0%-1.5%-10.6%
Payout Ratio ····0.00%0.00%·0.02%0.21%···
Annual Payout ····$0$0$11.0K$80.0K$281.0K$960.0K$87M$57M

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $411M $359M $310M $331M $392M
Operating Margin % · · · · 95.7%
Net Income $271M $23M $180M $220M $369M
Diluted EPS $3.30 $0.36 $2.20 $2.37 $2.87

Institutional owners (13F) 322 filers · $1.8B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 322
Value held $1.8B
New positions 44
Exited positions 21
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
44 (-12 vs prior Q) 21 (-13 vs prior Q) 131 (+20 vs prior Q) 83 (-1 vs prior Q) +3K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BlackRock, Inc. $262,418,797 11,555,209 14.33% Shares
VANGUARD GROUP INC $158,262,890 7,917,103 8.64% Shares
DIMENSIONAL FUND ADVISORS LP $102,062,559 4,494,053 5.57% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $95,842,400 4,220,273 5.24% Shares
RENAISSANCE TECHNOLOGIES LLC $91,669,642 4,036,532 5.01% Shares
STATE STREET CORP $74,216,371 3,268,004 4.05% Shares
VANGUARD CAPITAL MANAGEMENT LLC $71,719,384 3,158,053 3.92% Shares
MILLENNIUM MANAGEMENT LLC $57,708,585 2,541,109 3.15% Shares
GEODE CAPITAL MANAGEMENT, LLC $47,125,306 2,074,709 2.57% Shares
SYSTEMATIC FINANCIAL MANAGEMENT LP $45,955,194 2,023,565 2.51% Shares
Boston Partners $43,777,396 1,927,959 2.39% Shares
Sarissa Capital Management LP $42,935,617 1,890,604 2.35% Shares
BANK OF AMERICA CORP /DE/ $37,873,400 1,667,697 2.07% Shares
GOLDMAN SACHS GROUP INC $36,792,312 1,620,093 2.01% Shares
AMERICAN CENTURY COMPANIES INC $34,020,579 1,498,044 1.86% Shares
MARSHALL WACE, LLP $33,027,585 1,454,319 1.80% Shares
MORGAN STANLEY $27,725,102 1,220,831 1.51% Shares
ROYCE & ASSOCIATES LP $26,631,790 1,172,690 1.45% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $26,146,182 1,151,307 1.43% Shares
TWO SIGMA INVESTMENTS, LP $23,455,047 1,032,807 1.28% Shares
Qube Research & Technologies Ltd $22,122,356 974,124 1.21% Shares
DEUTSCHE BANK AG\ $20,846,894 917,961 1.14% Shares
NORTHERN TRUST CORP $18,876,530 831,199 1.03% Shares
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main $18,857,793 830,374 1.03% Shares
Invesco Ltd. $16,640,071 732,720 0.91% Shares
Nuveen, LLC $15,158,154 667,466 0.83% Shares
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC $14,583,817 642,176 0.80% Shares
VICTORY CAPITAL MANAGEMENT INC $14,211,963 625,802 0.78% Shares
AQR CAPITAL MANAGEMENT LLC $12,480,349 549,553 0.68% Shares
UBS Group AG $12,349,494 543,791 0.67% Shares
Bank of New York Mellon Corp $11,607,062 511,099 0.63% Shares
Allianz Asset Management GmbH $11,029,770 485,679 0.60% Shares
Russell Investments Group, Ltd. $10,867,504 478,533 0.59% Shares
VANGUARD FIDUCIARY TRUST CO $10,654,079 469,136 0.58% Shares
Assenagon Asset Management S.A. $10,088,282 444,222 0.55% Shares
PRINCIPAL FINANCIAL GROUP INC $9,461,440 416,620 0.52% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $7,954,246 350,253 0.43% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $7,725,215 340,168 0.42% Shares
Empowered Funds, LLC $7,407,935 326,197 0.40% Shares
FIRST TRUST ADVISORS LP $6,489,314 285,747 0.35% Shares
Balyasny Asset Management L.P. $6,486,203 285,610 0.35% Shares
Baird Financial Group, Inc. $6,231,420 274,391 0.34% Shares
FRANKLIN RESOURCES INC $6,203,690 273,170 0.34% Shares
JANE STREET GROUP, LLC $6,153,002 270,938 0.34% Shares
Edgestream Partners, L.P. $6,116,893 269,348 0.33% Shares
Uniplan Investment Counsel, Inc. $6,000,241 264,211 0.33% Shares
Public Sector Pension Investment Board $5,471,021 240,908 0.30% Shares
ASSETMARK, INC $5,162,437 227,320 0.28% Shares
ENVESTNET ASSET MANAGEMENT INC $4,942,741 217,646 0.27% Shares
AMERIPRISE FINANCIAL INC $4,777,253 210,359 0.26% Shares

Show all 322 institutional owners →

Activists & 5%+ owners 5 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Innoviva, Inc., Innoviva Strategic Opportunities LLC ×24 filings May 13, 2026 82.70% Amendment · SEC
Sarissa Capital Management LP, DENNER ALEXANDER J ×2 filings March 17, 2025 4.70% Amendment · SEC
Innoviva, Inc, Innoviva Strategic Opportunities LLC ×2 filings Nov. 14, 2024 · Initial filing · SEC
OR ×4 filings May 15, 2023 · Initial filing · SEC
April 5, 2021 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 53 insiders · 23 officers · 28 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Pavel Raifeld Chief Executive Officer Aug. 20, 2026 F 284,799 0 0 $0
Stephen Basso Chief Financial Officer Aug. 20, 2026 F 88,013 0 0 $0
Eric Desparbes SVP and CFO May 21, 2018 S 373,081 0 0 $0
Marty Glick Executive VP, Finance and CFO Oct. 5, 2004 P 267,805 0 0 $0
Matthew Ronsheim Dr. Ronsheim is President of Innoviva Specialty Therapeutics, Inc. which is a wholly owned subsidiary of Innoviva Specialty Ther May 20, 2024 F 40,510 0 0 $0
Michael W Aguiar President & Chief Exec Officer Dec. 4, 2017 S 980,907 0 0 $0
Marianne Zhen Chief Accounting Officer Aug. 20, 2026 F 56,389 0 0 $0
Margaret Koziel Chief Medical Officer July 31, 2023 A · 0 0 $0
Geoffrey Hulme Interim Principal Exec Officer May 20, 2020 F 46,251 0 0 $0
Theodore L Witek JR Sr. VP & Chief Scientific Off. Aug. 21, 2018 S 247,767 0 0 $0
George B Abercrombie Sr. VP & Chief Comm. Officer Aug. 21, 2018 S 285,479 0 0 $0
Michael E. Faerm Sr VP & Chief Business Officer Nov. 20, 2017 F 279,422 0 0 $0
Junning Lee Sr. VP, Technical Operations Aug. 20, 2014 F 262,198 0 0 $0
Mathai Mammen SVP, Research & Early Clin Dev Aug. 20, 2014 F 334,040 0 0 $0
Bradford J Shafer Sr VP, Gen. Counsel, Secretary Aug. 20, 2014 F 443,013 0 0 $0
Leonard M Blum Sr VP, Chief Comm. Officer June 16, 2014 A 404,799 0 0 $0
Frank Pasqualone Sr. Vice President, Operations Jan. 23, 2014 A 20,000 0 0 $0
Jeffrey David Jonker Senior VP, Corp. & Bus. Dev. Oct. 22, 2013 A 15,000 0 0 $0
David L Brinkley Head of Business Dev. May 29, 2013 S 48,749 0 0 $0
Michael Kitt Sr. Vice President Development June 4, 2008 M 30,738 0 0 $0
Arthur L Campbell Sr. VP, Technical Operations Jan. 29, 2008 A 5,376 0 0 $0
Patrick Pa Humphrey Executive VP Research Dec. 10, 2007 M 54,310 0 0 $0
Gregory A Sturmer Vice President Finance Feb. 10, 2005 A 290 0 0 $0
Josephine Linden Director May 18, 2026 A 15,194 0 0 $0
Mark Dipaolo Director May 4, 2026 A 140,492 0 0 $0
Derek A Small Director May 4, 2026 A 45,035 0 0 $0
Sarah J. Schlesinger Director May 4, 2026 A 140,492 0 0 $0
Jules Haimovitz Director May 4, 2026 A 152,692 0 0 $0
Sapna Srivastava Director June 17, 2024 A 44,096 0 0 $0
Odysseas D Kostas Director June 17, 2024 A 122,625 0 0 $0
Deborah Birx Director May 22, 2023 A 58,984 0 0 $0
George Bickerstaff Director April 25, 2022 A 137,207 0 0 $0
Paul Pepe Director April 20, 2017 A 73,805 0 0 $0
Barbara Gayle Duncan Director April 20, 2017 A 52,318 0 0 $0
James L Tyree Director April 20, 2017 A 70,554 0 0 $0
William H Waltrip Director April 20, 2017 A 161,789 0 0 $0
Patrick G Lepore Director April 20, 2017 A 58,278 0 0 $0
Terrence C Kearney Director April 24, 2015 A 37,083 0 0 $0
Rick E Winningham Director Aug. 15, 2014 D 825,391 0 0 $0
Henrietta Fore Director May 22, 2014 A 33,000 0 0 $0
Robert V Gunderson JR Director May 22, 2014 A 115,970 0 0 $0
George M Whitesides Director May 22, 2014 A 606,377 0 0 $0
William D Young Director May 22, 2014 A 83,935 0 0 $0
Peter S Ringrose Director May 22, 2014 A 36,000 0 0 $0
Burton G Malkiel Director May 22, 2014 A 40,000 0 0 $0
DRAZAN JEFFREY M Director May 1, 2012 S 33,465 0 0 $0
Eve Elizabeth Slater Director April 25, 2007 A · 0 0 $0
Ronn Loewenthal Director May 2, 2006 M 0 0 0 $0
Julian C. Baker Director April 26, 2006 A 0 0 0 $0
GSK plc · May 20, 2021 S 0 0 0 $0
Cathy Friedman · April 20, 2017 A 73,805 0 0 $0
Arnold J Levine · March 21, 2014 M 111,794 0 0 $0
VAGELOS P ROY · Dec. 23, 2009 M 404,802 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 66 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PJP · Invesco Exchange-Traded Fund Trust 3.21% 844,579 SH Oct. 1, 2026 Daily
SCOW · Pacer Funds Trust 1.04% 851 NS July 31, 2026 N-PORT
PILL · Direxion Shares ETF Trust 1.04% 10,214 NS July 31, 2026 N-PORT
RNIN · EA Series Trust 0.98% 84,978 NS July 31, 2026 N-PORT
PSCH · Invesco Exchange-Traded Fund Trust … 0.83% 69,613 SH Oct. 1, 2026 Daily
HSMV · First Trust Exchange-Traded Fund III 0.63% 10,579 NS July 31, 2026 N-PORT
CAFG · Pacer Funds Trust 0.59% 8,470 NS July 31, 2026 N-PORT
FYT · First Trust Exchange-Traded AlphaDE… 0.57% 52,620 NS July 31, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.53% 5,773 SH Oct. 1, 2026 Daily
ROSC · Lattice Strategies Trust 0.49% 14,251 NS July 31, 2026 N-PORT
VFMV · VANGUARD WELLINGTON FUND 0.46% 84,775 SH Aug. 19, 2026 Daily
XSHQ · Invesco Exchange-Traded Fund Trust … 0.46% 61,253 SH Oct. 1, 2026 Daily
IHE · iShares Trust 0.33% 259,677 SH Sept. 11, 2026 Daily
FYX · First Trust Exchange-Traded AlphaDE… 0.29% 192,060 NS July 31, 2026 N-PORT
JPSE · J.P. Morgan Exchange-Traded Fund Tr… 0.24% 68,619 NS July 31, 2026 N-PORT
SMDX · Tidal Trust III 0.19% 11,742 NS July 31, 2026 N-PORT
CALF · Pacer Funds Trust 0.16% 281,067 NS July 31, 2026 N-PORT
FAB · First Trust Exchange-Traded AlphaDE… 0.11% 9,099 NS July 31, 2026 N-PORT
VTWV · VANGUARD SCOTTSDALE FUNDS 0.11% 65,756 SH Aug. 19, 2026 Daily
DFSV · Dimensional ETF Trust 0.11% 425,619 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.10% 5,119 SH Oct. 1, 2026 Daily
VIOG · VANGUARD ADMIRAL FUNDS 0.10% 49,242 SH Aug. 19, 2026 Daily
QVMS · Invesco Exchange-Traded Fund Trust … 0.09% 10,402 SH Oct. 1, 2026 Daily
FSMD · FIDELITY COVINGTON TRUST 0.09% 110,972 NS July 31, 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0.09% 245,491 SH Aug. 19, 2026 Daily
EBIT · Harbor ETF Trust 0.08% 455 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.08% 96,256 SH Oct. 1, 2026 Daily
DFAT · Dimensional ETF Trust 0.07% 508,220 NS July 31, 2026 N-PORT
VIOV · VANGUARD ADMIRAL FUNDS 0.07% 61,003 SH Aug. 19, 2026 Daily
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.06% 19,394 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.05% 1,938,845 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.05% 36,129 NS July 31, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.05% 434,766 SH Aug. 19, 2026 Daily
DFAS · Dimensional ETF Trust 0.03% 241,993 NS July 31, 2026 N-PORT
VBR · VANGUARD INDEX FUNDS 0.03% 1,021,419 SH Aug. 19, 2026 Daily
VFVA · VANGUARD WELLINGTON FUND 0.03% 10,116 SH Aug. 19, 2026 Daily
RWJ · Invesco Exchange-Traded Fund Trust … 0.03% 27,199 SH Oct. 1, 2026 Daily
ISCG · iShares Trust 0.03% 12,247 SH Sept. 11, 2026 Daily
OMFS · Invesco Exchange-Traded Self-Indexe… 0.03% 3,144 SH Oct. 1, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.02% 33,538 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.02% 803,072 SH Aug. 19, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.02% 1,610,347 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.02% 211,449 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.01% 4,033 SH Sept. 11, 2026 Daily
DFAC · Dimensional ETF Trust 0.01% 198,691 NS July 31, 2026 N-PORT
DFUV · Dimensional ETF Trust 0.01% 53,396 NS July 31, 2026 N-PORT
TILT · FlexShares Trust 0.01% 6,691 NS July 31, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.01% 1,559 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.01% 8,987 NS July 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 20,704 NS July 31, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 24,791 NS July 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 103,511 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 19,040 SH Sept. 3, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 2,231,526 SH Aug. 19, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.00% 52,609 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 6,178 SH Aug. 19, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.00% 16,651 SH Aug. 19, 2026 Daily
IJR · iShares Trust · 4,277,518 SH Sept. 10, 2026 Daily
IJT · iShares Trust · 392,937 SH Sept. 9, 2026 Daily
IJS · iShares Trust · 254,717 SH Sept. 8, 2026 Daily
IWN · iShares Trust · 710,119 SH Sept. 11, 2026 Daily
XJR · iShares Trust · 9,719 SH Aug. 31, 2026 Daily
SVAL · iShares Trust · 26,399 SH Sept. 3, 2026 Daily
ISCB · iShares Trust · 3,289 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 7,550 SH Sept. 11, 2026 Daily
SMMV · iShares Trust · 29,790 SH Sept. 1, 2026 Daily

INVA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 11 analysts BUY
Median target $35.00 +70.7%
4 36.4% Strong Buy
5 45.5% Buy
1 9.1% Hold
1 9.1% Sell
0 0.0% Strong Sell

12-Month Price Target

5 analysts · 2026-09-29

Mean target $35.00 +70.7%

Now Current price $20.50
Low$18.00 Mean$35.00 High$46.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
INVA · 6.1 14.7% · · ·
OCUL $2.62B -8.5 -18.5% -511.9% -55.4% ·
ETON $457M · 104.9% -5.8% -18.4% 53.5%
RAPP $1.45B -10.6 · · -29.8% ·
NKTR $862M -4.3 -43.9% -297.1% -500.1% ·
PAHC · 12.9 17.1% 6.6% 29.7% 33.8%
MAZE $2.04B -13.6 · · -598.9% ·
XERS $1.30B · 43.7% 0.19% -19.7% ·
KARD · · · · · ·
OMER $1.23B -343.6 · · 1.9% ·
AVLN · · · · · ·

Latest News Recent headlines mentioning this company

23

Trading Signals Recent buy/sell signals with entry price and risk/reward ratio

25

No open signal right now — no card is filled, and that's honest.

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 5, 2026