Insider at

04

Insider transactions

05
0 buys (P) 0 sells (S) Net: $0 + 50 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

50 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
March 13, 2025 MDGL S 1,951 $322.45 $629,100 355,867 Direct -0.55% Disposed 54.9% (price as of 2026-10-02)
March 13, 2025 MDGL S 1,649 $323.47 $533,402 354,218 Direct -0.46% Disposed 54.4% (price as of 2026-10-02)
March 13, 2025 MDGL S 900 $324.69 $292,221 353,318 Direct -0.25% Disposed 53.8% (price as of 2026-10-02)
March 13, 2025 MDGL S 800 $325.63 $260,504 352,518 Direct -0.23% Disposed 53.4% (price as of 2026-10-02)
March 13, 2025 MDGL S 1,000 $327.63 $327,630 351,518 Direct -0.28% Disposed 52.4% (price as of 2026-10-02)
March 13, 2025 MDGL S 400 $328.68 $131,472 351,118 Direct -0.11% Disposed 51.9% (price as of 2026-10-02)
March 13, 2025 MDGL S 967 $329.86 $318,975 350,151 Direct -0.28% Disposed 51.4% (price as of 2026-10-02)
March 13, 2025 MDGL S 75 $330.22 $24,766 350,076 Direct -0.02% Disposed 51.2% (price as of 2026-10-02)
March 12, 2025 MDGL S 1,587 $330.54 $524,567 356,217 Direct -0.44% Disposed 51.1% (price as of 2026-10-02)
March 12, 2025 MDGL S 2,759 $331.36 $914,222 353,458 Direct -0.77% Disposed 50.7% (price as of 2026-10-02)
March 12, 2025 MDGL S 2,382 $332.38 $791,729 351,076 Direct -0.67% Disposed 50.2% (price as of 2026-10-02)
March 12, 2025 MDGL S 800 $333.66 $266,928 350,276 Direct -0.23% Disposed 49.7% (price as of 2026-10-02)
March 12, 2025 MDGL S 200 $334.97 $66,994 350,076 Direct -0.06% Disposed 49.1% (price as of 2026-10-02)
Dec. 3, 2024 MDGL S 3,080 $315.21 $970,847 11,520 Indirect -21.10% Disposed 58.4% (price as of 2026-10-02)
Dec. 3, 2024 MDGL S 520 $315.90 $164,268 11,000 Indirect -4.51% Disposed 58.1% (price as of 2026-10-02)
Nov. 25, 2024 MDGL S 2,200 $350.08 $770,176 15,800 Indirect -12.22% Disposed 42.7% (price as of 2026-10-02)
Nov. 25, 2024 MDGL S 1,200 $350.71 $420,852 14,600 Indirect -7.59% Disposed 42.4% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 100 $219.90 $21,990 413,362 Direct -0.02% Disposed 127.1% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 1,000 $218.99 $218,990 413,462 Direct -0.24% Disposed 128.0% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 1,100 $217.86 $239,646 414,462 Direct -0.26% Disposed 129.2% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 721 $216.98 $156,443 415,562 Direct -0.17% Disposed 130.2% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 375 $216.08 $81,030 416,283 Direct -0.09% Disposed 131.1% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 1,804 $214.68 $387,283 416,658 Direct -0.43% Disposed 132.6% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 2,190 $213.85 $468,332 418,462 Direct -0.52% Disposed 133.5% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 1,363 $212.85 $290,115 420,652 Direct -0.32% Disposed 134.6% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 5,009 $211.84 $1,061,107 422,015 Direct -1.17% Disposed 135.7% (price as of 2026-10-02)
May 14, 2024 MDGL S 10b5-1 8,827 $210.99 $1,862,409 427,024 Direct -2.03% Disposed 136.7% (price as of 2026-10-02)
Aug. 19, 2020 MDGL S 7,303 $107.64 $786,095 42,875 Indirect -14.55% Disposed 364.0% (price as of 2026-10-02)
Aug. 18, 2020 MDGL S 10,197 $110.03 $1,121,976 50,178 Indirect -16.89% Disposed 353.9% (price as of 2026-10-02)
Aug. 17, 2020 MDGL S 12,500 $110.73 $1,384,125 60,375 Indirect -17.15% Disposed 351.0% (price as of 2026-10-02)
Dec. 13, 2019 MDGL S 25,320 $105.47 $2,670,500 88,152 Indirect -22.31% Disposed 373.5% (price as of 2026-10-02)
Dec. 13, 2019 MDGL S 1,174,680 $105.47 $123,893,500 4,089,702 Indirect -22.31% Disposed 373.5% (price as of 2026-10-02)
Nov. 19, 2018 MDGL P 900 $125.00 $112,500 298,067 Direct +0.30% Acquired 299.5% (price as of 2026-10-02)
Nov. 19, 2018 MDGL P 1,000 $124.57 $124,570 297,167 Direct +0.34% Acquired 300.9% (price as of 2026-10-02)
Nov. 19, 2018 MDGL P 100 $123.17 $12,317 296,167 Direct +0.03% Acquired 305.5% (price as of 2026-10-02)
June 11, 2018 MDGL S 5,908 $287.46 $1,698,314 113,472 Indirect -4.95% Disposed 73.7% (price as of 2026-10-02)
June 11, 2018 MDGL S 5,908 $287.46 $1,698,314 113,472 Indirect +5.49% Acquired 73.7% (price as of 2026-10-02)
June 11, 2018 MDGL S 274,092 $287.46 $78,790,486 5,264,382 Indirect -4.95% Disposed 73.7% (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

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DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
March 13, 2025 MDGL Stock Option (Right to Buy) Common Stock (7,742) $65.06 June 16, 2025 7,742 Disposed
March 12, 2025 MDGL Stock Option (Right to Buy) Common Stock (1,728) $65.06 June 16, 2025 1,728 Disposed
March 12, 2025 MDGL Stock Option (Right to Buy) Common Stock (6,000) $111.06 June 17, 2025 6,000 Disposed
June 25, 2024 MDGL Stock Option (Right to Buy) Common Stock (1,105) $280.04 June 25, 2031 1,105 Acquired
May 14, 2024 MDGL Stock Option (right to buy) Common Stock (12,489) $105.08 June 17, 2024 12,489 Disposed
May 14, 2024 MDGL Stock Option (right to buy) Common Stock (10,000) $100.45 June 27, 2024 10,000 Disposed
June 16, 2022 MDGL Stock Option (Right to Buy) Common Stock (9,470) $65.06 June 16, 2025 9,470 Acquired
June 17, 2021 MDGL Stock Option (Right to Buy) Common Stock (12,489) $105.08 June 17, 2024 12,489 Acquired
June 17, 2020 MDGL Stock Option (Right to Buy) Common Stock (6,000) $111.06 June 17, 2025 6,000 Acquired
July 23, 2019 TWST Director Stock Option (right to buy) Common Stock (5,590) $30.41 July 22, 2029 5,590 Acquired
June 27, 2019 MDGL Stock Option (Right to Buy) Common Stock (10,000) $100.45 June 27, 2024 10,000 Acquired
Nov. 2, 2018 TWST Series D Preferred Stock Common Stock (8,603) · · 8,603 Disposed
Nov. 2, 2018 TWST Series C Preferred Stock Common Stock (7,158) · · 7,158 Disposed
Nov. 2, 2018 TWST Series B Preferred Stock Common Stock (51,010) · · 51,010 Disposed
June 19, 2018 MDGL Stock Option (Right to Buy) Common Stock (10,000) $303.79 June 19, 2028 10,000 Acquired
June 29, 2017 MDGL Stock Option (Right to Buy) Common Stock (10,000) $16.46 June 29, 2027 10,000 Acquired
July 22, 2016 MDGL Stock Option (Right to Buy) Common Stock (20,000) · July 22, 2026 20,000 Acquired
July 22, 2016 MDGL Stock Option (Right to Buy) Common Stock (20,000) $12.01 July 22, 2026 20,000 Acquired
June 1, 2005 INCY Non-Qualified Stock Options Common stock (20,000) $7.68 June 1, 2015 20,000 Acquired
May 25, 2004 INCY Non-Qualified Stock Options Common Stock (10,000) $70.02 May 25, 2014 10,000 Acquired
May 25, 2004 INCY Non-Qualified Stock Option (right to buy) Common Stock (10,000) $7.02 May 25, 2014 10,000 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 4 holdings

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Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Oct. 30, 2018 TWST Common Stock 0 Direct
Oct. 30, 2018 TWST Series B Preferred Stock→ Common Stock (51,010) 51,010 Indirect
Oct. 30, 2018 TWST Series C Preferred Stock→ Common Stock (7,158) 7,158 Indirect
Oct. 30, 2018 TWST Series D Preferred Stock→ Common Stock (8,603) 8,603 Indirect