Insider at

04

Insider transactions

05
0 buys (P) 0 sells (S) Net: $0 + 7 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

No open-market trades on record; showing all filings.

DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Aug. 18, 2017 AVTX A 25,000 · · 25,000 Direct · Acquired (price as of 2026-10-02)
Jan. 26, 2017 AVTX A 25,000 · · 25,000 Direct · Acquired (price as of 2026-10-02)
Aug. 17, 2016 AVTX A 32,500 · · 32,500 Direct · Acquired (price as of 2026-10-02)
Feb. 24, 2016 AVTX A 31,288 · · 31,288 Direct · Acquired (price as of 2026-10-02)
Oct. 20, 2015 AVTX A 40,000 · · 40,000 Direct · Acquired (price as of 2026-10-02)
Oct. 20, 2008 ACAD A 40,000 · · 40,000 Direct · Acquired (price as of 2026-10-02)
March 7, 2008 ACAD A 85,000 · · 85,000 Direct · Acquired (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
Aug. 18, 2017 AVTX Employee Stock Option (Right to Buy) Common Stock (25,000) $0.62 Aug. 18, 2027 25,000 Acquired
Jan. 26, 2017 AVTX Employee Stock Option (Right to Buy) Common Stock (25,000) $0.87 Jan. 25, 2027 25,000 Acquired
Aug. 17, 2016 AVTX Employee Stock Option (Right to Buy) Common Stock (32,500) $3.77 Aug. 16, 2026 32,500 Acquired
Feb. 24, 2016 AVTX Employee Stock Option (Right to Buy) Common Stock (31,288) $3.01 Feb. 24, 2026 31,288 Acquired
Oct. 20, 2015 AVTX Employee Stock Option (Right to Buy) Common Stock (40,000) $6.49 Oct. 19, 2024 40,000 Acquired
Oct. 20, 2008 ACAD Stock Option (right to buy) Common Stock (40,000) $2.00 Oct. 19, 2018 40,000 Acquired
March 7, 2008 ACAD Stock option (right to buy) Common Stock (85,000) $8.32 March 6, 2018 85,000 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 3 holdings

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Oct. 14, 2015 AVTX Stock Option (Right to Buy)→ Common Stock (14,285) 14,285 Direct
Oct. 14, 2015 AVTX Stock Option (Right to Buy)→ Common Stock (7,142) 7,142 Direct
Oct. 14, 2015 AVTX Stock Option (Right to Buy)→ Common Stock (19,285) 19,285 Direct

Compensation (DEF 14A)

08

Matched by name from proxy statements (DEF 14A) — verify against the filing.

Fiscal yearSalaryBonusStock awards Option awardsNon-equity incentivePension changeOtherTotal
2009 $288,632 $50,000 · · · · $12,845 $351,477
2008 $245,913 $110,500 · · · · $80,068 $526,696

AVTX

CEO
Fiscal yearSalaryBonusStock awards Option awardsNon-equity incentivePension changeOtherTotal
2017 $321,871 · · $27,055 · · $6,718 $355,644
2016 $297,000 · · $153,411 · · · $450,411
2015 $292,013 $89,100 · $117,004 · · · $498,117

Figures from the Summary Compensation Table of the company's proxy statement (DEF 14A). Compensation is not a recommendation.