AVTX Avalo Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$19.98
Price · Aug 18, 2026
Fundamentals as of Aug 6, 2026

AVTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$19.98
Market Cap
$492M
P/E (TTM)
-4.6
EPS (TTM)
$-5.84
Revenue (TTM)
$59.0K
Div Yield
ROE
-83.4%
Debt/Equity
52W Range
$8 – $24

AVTX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $59.0K
10-point trend, -94.9%
2016-12-31 2025-12-31
EPS $-5.84
7-point trend, -212.3%
2016-12-31 2025-12-31
Free Cash Flow
5-point trend, -83.8%
2016-12-31 2022-12-31
Margins -132642.4%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
AVTX
Peer Median
P/E (TTM)
5-point trend, +100.0%
-4.6
P/S (TTM)
5-point trend, -94.4%
8343.4
27.3
P/B
5-point trend, -100.0%
5.9
3.9

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
AVTX
Peer Median
Operating Margin
5-point trend, -8023.4%
-123601.7%
Net Profit Margin
5-point trend, -8385.9%
-132642.4%
-352.8%
ROA
5-point trend, +57.0%
-58.6%
-36.2%
ROE
5-point trend, +68.7%
-83.4%
-42.0%
ROIC
3-point trend, +76.5%
-88.0%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
AVTX
Peer Median
Current Ratio
5-point trend, +161.6%
8.1
12.0
Quick Ratio
5-point trend, +176.9%
7.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
AVTX
Peer Median
Revenue YoY
5-point trend, -98.9%
-86.6%
Revenue CAGR 3Y
5-point trend, -98.9%
-85.2%
Revenue CAGR 5Y
5-point trend, -98.9%
-61.2%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
AVTX
Peer Median
EPS (Diluted)
5-point trend, -386.7%
$-5.84

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
AVTX
Peer Median

AVTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 21 analysts
  • Strong Buy 10 47.6%
  • Buy 10 47.6%
  • Hold 1 4.8%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

13 analysts · 2026-08-14
Median target $42.00 +110.2%
Mean target $44.15 +121.0%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-1.2%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.83 $-0.59 -0.24%
March 31, 2026 $-0.98 $-1.05 0.07%
Dec. 31, 2025 $-1.13 $-1.49 0.36%
Sept. 30, 2025 $-2.19 $-1.69 -0.50%
June 30, 2025 $-1.92 $-1.43 -0.49%
March 31, 2025 $-1.25 $-1.41 0.16%
Dec. 31, 2024 $-7.95 $-0.40 -7.6%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
AVTX $336M -3.1 -86.6% -132642.4% -83.4%
REPL $633M -2.3 -146.2%
VOR $506M -0.2 83.4%
SANA $1.09B -4.2 -172.3%
SVRA $1.23B -11.4 -73.4%
ARDX $1.42B -22.4 22.1% -15.1% -40.2%
ODTX
KURA $913M -3.3 25.2% -413.0% -116.2%
JANX $833M -7.5 -5.5% -1136.2% -11.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Revenue 11-point trend, +59000.00 $59.0K $441.0K $2M $18M $5M $7M $7M $7M $28M $1M $0
Cost of Revenue 9-point trend, +1284000.00 · · $1M $3M $1M $300.0K $-566.5K $3M $635.6K $0 $0
R&D Expense 4-point trend, -12.2% · · · · · · · $6M $4M $10M $7M
SG&A Expense 11-point trend, +417.8% $23M $17M $10M $21M $25M $17M $10M $11M $8M $7M $4M
Operating Expenses 11-point trend, +562.9% $73M $69M $29M $55M $88M $80M $23M $42M $14M $17M $11M
Operating Income 11-point trend, -562.4% $-73M $-69M $-27M $-37M $-82M $-73M $-16M $-35M $14M $-16M $-11M
Other Non-op 11-point trend, -1094.3% $-5M $33M $-42.0K $-20.0K $-20.0K $409.0K $-28.3K $13.7K $0 $-391.6K $519.8K
Pretax Income 4-point trend, -87.6% $-78M $-35M $-32M $-42M · · · · · · ·
Income Tax 11-point trend, +165000.00 $165.0K $114.0K $14.0K $28.0K $-196.0K $-3M $280.3K $-49.5K $2M $0 $0
Net Income 11-point trend, -646.0% $-78M $-35M $-32M $-42M $-84M $-64M $-16M $-40M $12M $-16M $-10M
EPS (Basic) 8-point trend, -24.0% $-5.84 $-7.94 $-113.58 $-1063.00 · · · $-1.20 $0.42 $-1.87 $-4.71
EPS (Diluted) 8-point trend, -24.0% $-5.84 $-20.91 $-113.58 $-1063.00 · · · $-1.20 $0.42 $-1.87 $-4.71
Shares (Basic) 8-point trend, +502.2% 13,404,830 4,426,149 277,727 39,202 · · · 34,773,613 18,410,005 8,830,396 2,226,023
Shares (Diluted) 8-point trend, +502.2% 13,404,830 7,496,389 277,727 39,202 · · · 34,773,613 18,754,799 8,830,396 2,226,023
EBITDA 9-point trend, -559.2% $-73M $-68M $-27M $-37M $-80M $-71M $-12M · · $-16M $-11M
Balance Sheet 28
Annual Balance Sheet data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, -25.1% $16M $135M $7M $13M $55M $19M $4M $11M $2M $5M $21M
Short-term Investments 2-point trend, +82478000.00 $82M $0 · · · · · · · · ·
Receivables · · · $0 · · · · · · ·
Inventory 8-point trend, +0.00 · · $0 $20.0K $38.0K $3.0K $21.3K $317.9K $382.2K $0 ·
Prepaid Expense 11-point trend, +1621.6% $7M $4M $843.0K $1M $2M $3M $707.0K $732.0K $703.2K $391.3K $401.6K
Current Assets 11-point trend, +386.9% $105M $139M $8M $16M $62M $26M $18M $22M $11M $6M $22M
PP&E (Net) 5-point trend, +4010.8% · · · · · · $1M $586.5K $44.6K $43.2K $35.2K
PP&E (Gross) 4-point trend, +648.2% · · · · · · · $718.7K $154.3K $130.9K $96.1K
Accum. Depreciation 4-point trend, +117.2% · · · · · · · $132.2K $109.6K $87.7K $60.8K
Goodwill 10-point trend, +10502000.00 $11M $11M $11M $14M $14M $14M $14M $14M $12M $0 ·
Intangibles 7-point trend, +0.00 · · · $0 $38.0K $2M $2M $4M $18M $0 ·
Total Assets 11-point trend, +437.7% $116M $151M $21M $33M $80M $44M $36M $70M $43M $6M $22M
Accounts Payable 11-point trend, -79.8% $137.0K $283.0K $446.0K $3M $3M $3M $2M $1M $1M $1M $678.1K
Short-term Debt 3-point trend, +0.00 · · $0 $6M $0 · · · · · ·
Current Liabilities 11-point trend, +121.2% $13M $7M $5M $22M $20M $15M $12M $26M $11M $4M $6M
Capital Leases 7-point trend, -96.9% $35.0K $350.0K $1M $2M $2M $1M $1M · · · ·
Deferred Tax 10-point trend, +434000.00 $434.0K $270.0K $155.0K $141.0K $113.0K $90.0K $86.0K $69.2K $7.1K $0 ·
Other Non-current Liabilities 11-point trend, -90.6% $35.0K $350.0K $1M $2M $2M $2M $1M $385.5K $24.3K $0 $370.5K
Total Liabilities 11-point trend, +289.7% $33M $18M $14M $44M $57M $19M $15M $49M $15M $6M $9M
Long-term Debt 4-point trend, +176.5% · · · · · · · $15M $0 $2M $6M
Total Debt 4-point trend, -100.0% · · $0 $6M · · · · · $2M $6M
Common Stock 11-point trend, +108.1% $18.0K $10.0K $1.0K $0 $9.0K $75.0K $44.4K $40.8K $31.3K $9.4K $8.7K
Paid-in Capital 11-point trend, +697.6% $531M $503M $342M $293M $285M $202M $135M $119M $83M $70M $67M
Retained Earnings 11-point trend, -737.4% $-449M $-370M $-335M $-304M $-262M $-178M $-114M $-98M $-58M $-70M $-54M
AOCI 2-point trend, +68000.00 $68.0K $0 · · · · · · · · ·
Stockholders' Equity 11-point trend, +534.8% $83M $133M $7M $-11M $23M $25M $21M $21M $28M $207.0K $13M
Liabilities + Equity 11-point trend, +437.7% $116M $151M $21M $33M $80M $44M $36M $70M $43M $6M $22M
Shares Outstanding 11-point trend, +114.0% 18,512,757 10,471,934 801,746 39,294 39,164 75,004,127 44,384,222 40,804,189 31,266,989 9,434,141 8,650,143
Cash Flow 14
Annual Cash Flow data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
D&A 11-point trend, +1363.3% $344.0K $169.0K $158.0K $166.0K $2M $2M $4M $5M $425.5K $26.9K $23.5K
Stock-based Comp 11-point trend, +3350.6% $14M $6M $3M $8M $8M $7M $3M $2M $1M $2M $394.7K
Deferred Tax 11-point trend, +165000.00 $165.0K $114.0K $14.0K $28.0K $22.0K $-196.0K $16.7K $-16.7K $-832.6K $0 $0
Amort. of Intangibles 8-point trend, +0.00 · · $0 $38.0K $2M $2M $1M $2M $400.0K $0 ·
Other Non-cash 7-point trend, +233.8% $13M $-20M $-3M $7M $4M $15M $-9M · · · ·
Operating Cash Flow 11-point trend, -406.3% $-51M $-49M $-31M $-27M $-71M $-41M $-19M $-3M $13M $-15M $-10M
CapEx 8-point trend, +375.4% · · · $95.0K $113.0K $63.0K $262.0K $564.4K $23.3K $34.9K $20.0K
Investing Cash Flow 11-point trend, -408827.1% $-82M $356.0K $-133.0K $-95.0K $-113.0K $11M $-443.0K $865.5K $-19M $-34.9K $-20.0K
Net Debt Issued 4-point trend, +100.0% · · · · · $0 $-256.1K · · $-3M $-2M
Stock Issued 11-point trend, +14762000.00 $15M $0 $32M $0 $29M $35M $9M $0 $2M $2M $0
Net Stock Activity 8-point trend, +636.9% $15M $0 $46M $0 $29M $35M $9M · · $2M ·
Financing Cash Flow 11-point trend, -25.6% $15M $176M $25M $-15M $107M $45M $13M $10M $4M $-1M $20M
Net Change in Cash 11-point trend, -1359.0% $-119M $127M $-6M $-42M $36M $15M $-7M $8M $-3M $-16M $9M
Free Cash Flow 6-point trend, -163.6% · · · $-27M $-71M $-41M $-19M · · $-15M $-10M
Profitability 7
Annual Profitability data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Operating Margin 7-point trend, -51603.2% -123601.7% -15535.6% -1421.6% -207.4% -1521.6% -1087.4% -239.1% · · · ·
Net Margin 7-point trend, -55512.9% -132642.4% -7965.8% -1639.5% -230.8% -1563.1% -947.9% -238.5% · · · ·
Pretax Margin 3-point trend, -7977.0% -132362.7% -7939.9% -1638.8% · · · · · · · ·
EBITDA Margin 7-point trend, -67667.7% -123018.6% -15497.3% -1413.4% -206.5% -1490.9% -1059.9% -181.5% · · · ·
ROA 9-point trend, +5.1% -58.6% -40.9% -116.1% -73.4% -136.1% -159.0% -30.3% · · -120.1% -61.8%
ROE 9-point trend, -152.7% -83.4% -45.6% -286.8% 643.7% -266.2% -201.2% -82.1% · · -247.9% 158.4%
ROIC 3-point trend, +76.5% -88.0% -51.7% -374.6% · · · · · · · ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Current Ratio 9-point trend, +120.1% 8.1 20.0 1.8 0.7 3.1 1.7 1.5 · · 1.3 3.7
Quick Ratio 9-point trend, +110.1% 7.6 19.3 1.6 0.6 2.7 1.2 0.3 · · 1.2 3.6
Debt / Equity 4-point trend, -100.0% · · 0.0 -0.5 · · · · · 11.4 0.4
LT Debt / Equity 2-point trend, -100.0% · · · · · · · · · 0.0 0.2
Efficiency 2
Annual Efficiency data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Asset Turnover 7-point trend, -99.7% 0.0 0.0 0.1 0.3 0.1 0.2 0.1 · · · ·
Inventory Turnover 5-point trend, +3944.5% · · 128.4 118.4 72.7 24.5 -3.3 · · · ·
Per Share 5
Annual Per Share data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Book Value / Share 9-point trend, +196.6% $4.49 $12.70 $9.11 $-1.16 $0.20 $0.33 $0.47 · · $0.02 $1.51
Revenue / Share 4-point trend, -99.8% $0.00 $0.06 $6.93 $1.92 · · · · · · ·
Cash Flow / Share 4-point trend, -35.0% $-3.84 $-6.54 $-110.47 $-2.84 · · · · · · ·
Cash / Share 9-point trend, -65.0% $0.86 $12.85 $9.25 $1.40 $0.48 $0.25 $0.08 · · $0.54 $2.45
EPS (TTM) 8-point trend, -24.0% $-5.84 $-20.91 $-113.58 $-1063.00 · · · $-1.20 $0.42 $-1.87 $-4.71
Growth Rates 3
Annual Growth Rates data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Revenue YoY 5-point trend, -346.0% -86.6% -77.1% -89.3% 234.4% -19.4% · · · · · ·
Revenue CAGR 3Y 3-point trend, -150.3% -85.2% -56.6% -34.0% · · · · · · · ·
Revenue CAGR 5Y -61.2% · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for AVTX
Metric Trend 20252024202320222021202020192018201720162015
Revenue TTM 11-point trend, +59000.00 $59.0K $441.0K $2M $18M $5M $7M $7M $7M $28M $1M $0
Net Income TTM 11-point trend, -646.0% $-78M $-35M $-32M $-42M $-84M $-64M $-16M $-40M $12M $-16M $-10M
Market Cap 9-point trend, -99.6% $336M $78M $7M $11.41B $552.24B $570.27B $688.99B · · $23.91B $83.46B
Enterprise Value 4-point trend, -100.0% · · $-119.1K $11.40B · · · · · $23.91B $83.44B
P/E 8-point trend, +99.8% -3.1 -0.4 -0.1 -1.1 · · · -7752.0 21942.9 -1355.3 -2048.4
P/S 8-point trend, -72.5% 5698.2 176.4 3.8 631.9 102304.6 85127.8 102066.6 · · 20737.3 ·
P/B 9-point trend, -99.9% 4.0 0.6 1.0 -1045.1 23925.2 23218.0 32815.7 · · 115505.6 6378.7
P / Tangible Book 4-point trend, -100.0% 4.6 0.6 · · 63953.7 66558.3 · · · · ·
P / Cash Flow 9-point trend, +99.9% -6.5 -1.6 -0.2 -426.4 -7789.9 -14067.0 -36007.8 · · -1640.7 -8211.5
P / FCF 6-point trend, +94.8% · · · -424.9 -7777.5 -14045.3 -35521.4 · · -1636.8 -8195.4
EV / EBITDA 4-point trend, +100.0% · · 0.0 -305.8 · · · · · -1486.8 -7578.7
EV / FCF 3-point trend, +94.8% · · · -424.6 · · · · · -1636.6 -8193.9
EV / Revenue 3-point trend, -100.0% · · -0.1 631.5 · · · · · 20734.9 ·
Earnings Yield 8-point trend, -64220.0% -32.2% -281.4% -1248.1% -87.9% · · · -0.01% 0.00% -0.07% -0.05%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $59.0K$441.0K$2M$18M$5M
Operating Margin % -123601.7%-15535.6%-1421.6%-207.4%-1521.6%
Net Income $-78M$-35M$-32M$-42M$-84M
Diluted EPS $-5.84$-20.91$-113.58$-1063.00
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.0-0.5
Current Ratio 8.120.01.80.73.1
Quick Ratio 7.619.31.60.62.7
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-27M$-71M

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Institutional owners (13F) 138 filers · $1.1B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
67 (+33 vs prior Q) 26 (+9 vs prior Q) 43 (+7 vs prior Q) 16 (-1 vs prior Q) +33.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Deep Track Capital, LP $66,712,800 3,610,000 5.98% Shares
FMR LLC $64,220,273 3,475,123 5.76% Shares
Caligan Partners LP $58,468,244 3,163,866 5.24% Shares
TCG Crossover Management, LLC $55,756,378 3,017,120 5.00% Shares
Affinity Asset Advisors, LLC $53,592,000 2,900,000 4.81% Shares
STATE STREET CORP $53,394,024 2,889,287 4.79% Shares
FARALLON CAPITAL MANAGEMENT, L.L.C. $46,163,040 2,498,000 4.14% Shares
Point72 Asset Management, L.P. $44,112,240 2,387,026 3.96% Shares
Avoro Capital Advisors LLC $43,119,994 2,333,333 3.87% Shares
VANGUARD CAPITAL MANAGEMENT LLC $41,843,266 2,264,246 3.75% Shares
BVF INC/IL $38,356,072 2,075,545 3.44% Shares
Nantahala Capital Management, LLC $34,414,380 1,862,250 3.09% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $31,951,920 1,729,000 2.87% Shares
Soleus Capital Management, L.P. $30,583,993 1,654,978 2.74% Shares
BRAIDWELL LP $30,107,283 1,629,182 2.70% Shares
ALLIANCEBERNSTEIN L.P. $23,297,533 1,260,689 2.09% Shares
Logos Global Management LP $21,252,000 1,150,000 1.91% Shares
Commodore Capital LP $18,818,535 1,018,319 1.69% Shares
RA CAPITAL MANAGEMENT, L.P. $18,480,000 1,000,000 1.66% Shares
GEODE CAPITAL MANAGEMENT, LLC $17,333,308 937,633 1.55% Shares
GOLDMAN SACHS GROUP INC $16,917,571 915,453 1.52% Shares
Trails Edge Capital Partners, LP $16,481,961 891,881 1.48% Shares
AMERIPRISE FINANCIAL INC $16,127,145 872,681 1.45% Shares
Balyasny Asset Management L.P. $15,924,419 861,711 1.43% Shares
Vestal Point Capital, LP $14,322,000 775,000 1.28% Shares
Parkman Healthcare Partners LLC $14,161,039 766,290 1.27% Shares
BOOTHBAY FUND MANAGEMENT, LLC $12,973,902 702,051 1.16% Shares
Squarepoint Ops LLC $10,889,248 589,245 0.98% Shares
BAKER BROS. ADVISORS LP $10,164,000 550,000 0.91% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $9,247,429 500,402 0.83% Shares
Davern Capital Partners, LP $8,660,948 468,666 0.78% Shares
Seven Fleet Capital Management LP $8,104,441 438,552 0.73% Shares
Pivotal bioVenture Partners Investment Advisor LLC $8,020,930 434,033 0.72% Shares
FRANKLIN RESOURCES INC $7,469,450 404,191 0.67% Shares
Boxer Capital Management, LLC $6,930,000 375,000 0.62% Shares
RENAISSANCE TECHNOLOGIES LLC $6,601,056 357,200 0.59% Shares
Caption Management, LLC $6,371,904 344,800 0.57% Put option
DV EQUITIES, LLC $6,139,296 332,213 0.55% Shares
VANGUARD FIDUCIARY TRUST CO $6,002,452 324,808 0.54% Shares
Velan Capital Investment Management LP $5,995,873 324,452 0.54% Shares
CITADEL ADVISORS LLC $5,984,434 323,833 0.54% Shares
Schonfeld Strategic Advisors LLC $5,728,947 310,008 0.51% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $5,261,293 284,702 0.47% Shares
Vivo Capital, LLC $5,082,000 275,000 0.46% Shares
BANK OF AMERICA CORP /DE/ $4,796,762 259,565 0.43% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $4,470,312 241,900 0.40% Call option
Eagle Health Investments LP $4,344,519 235,093 0.39% Shares
SPHERA FUNDS MANAGEMENT LTD. $4,292,793 232,294 0.39% Shares
PERCEPTIVE ADVISORS LLC $4,062,144 219,813 0.36% Shares
Caption Management, LLC $3,880,800 210,000 0.35% Shares
Jump Financial, LLC $3,731,149 201,902 0.33% Shares
NAN FUNG TRINITY (HK) LTD $3,492,720 189,000 0.31% Shares
ACUTA CAPITAL PARTNERS, LLC $3,442,972 186,308 0.31% Shares
Walleye Capital LLC $3,430,128 185,613 0.31% Shares
RTW INVESTMENTS, LP $3,234,000 175,000 0.29% Shares
Ally Bridge Group (NY) LLC $2,772,000 150,000 0.25% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $2,540,538 137,475 0.23% Shares
BNP PARIBAS FINANCIAL MARKETS $2,477,928 134,087 0.22% Shares
CenterBook Partners LP $2,455,419 132,869 0.22% Shares
Moody Aldrich Partners LLC $2,320,755 125,582 0.21% Shares
HighVista Strategies LLC $2,265,832 122,610 0.20% Shares
BlackRock, Inc. $2,259,956 122,292 0.20% Shares
Aberdeen Group plc $2,257,683 122,169 0.20% Shares
SECTORAL ASSET MANAGEMENT INC $2,216,177 119,923 0.20% Shares
CITADEL ADVISORS LLC $2,080,848 112,600 0.19% Call option
LMR Partners LLP $1,738,968 94,100 0.16% Call option
Ikarian Capital, LLC $1,666,581 90,183 0.15% Shares
TD Asset Management Inc $1,431,720 77,474 0.13% Shares
TWO SIGMA INVESTMENTS, LP $1,239,897 67,094 0.11% Shares
CITIGROUP INC $1,230,823 66,603 0.11% Shares
JANE STREET GROUP, LLC $1,068,144 57,800 0.10% Call option
Rafferty Asset Management, LLC $1,042,475 56,411 0.09% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $994,206 53,799 0.09% Shares
RHUMBLINE ADVISERS $984,789 53,290 0.09% Shares
XTX Topco Ltd $971,734 52,583 0.09% Shares
TWO SIGMA ADVISERS, LP $897,104 49,400 0.08% Shares
Verition Fund Management LLC $706,675 38,240 0.06% Shares
Man Group plc $681,468 36,876 0.06% Shares
WELLS FARGO & COMPANY/MN $675,924 36,576 0.06% Shares
WELLINGTON MANAGEMENT GROUP LLP $615,717 33,318 0.06% Shares
Verdad Advisers, LP $606,643 32,827 0.05% Shares
DIMENSIONAL FUND ADVISORS LP $584,726 31,641 0.05% Shares
Bank of New York Mellon Corp $556,414 30,109 0.05% Shares
LMR Partners LLP $554,400 30,000 0.05% Put option
PROFUND ADVISORS LLC $523,150 28,309 0.05% Shares
GLENMEDE TRUST CO NA $522,614 28,280 0.05% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $503,155 27,227 0.05% Shares
Persistent Asset Partners Ltd $453,573 24,544 0.04% Shares
MetLife Investment Management, LLC $452,742 24,499 0.04% Shares
ENVESTNET ASSET MANAGEMENT INC $416,521 22,539 0.04% Shares
Virtus Investment Advisers, LLC $409,665 22,168 0.04% Shares
Vanguard Global Advisers, LLC $369,785 20,010 0.03% Shares
SEI INVESTMENTS CO $331,365 17,931 0.03% Shares
Invesco Ltd. $307,895 16,661 0.03% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $304,920 16,500 0.03% Put option
ExodusPoint Capital Management, LP $304,828 16,495 0.03% Shares
Quadrature Capital Ltd $284,684 15,405 0.03% Shares
NEW YORK STATE COMMON RETIREMENT FUND $271,656 14,700 0.02% Shares
CITADEL ADVISORS LLC $255,024 13,800 0.02% Put option
Jain Global LLC $234,437 12,686 0.02% Shares

Company insiders 48 insiders · 14 officers · 23 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Garry Arthur Neil Chief Executive Officer May 21, 2026 A 190,314 0 0 $0
Peter Greenleaf Chief Executive Officer March 27, 2018 A 400,000 0 0 $0
Blake M Paterson CEO and President Oct. 20, 2015 A 0 0 $0
Christopher Ryan Sullivan Chief Financial Officer June 10, 2026 F 40,773 0 0 $0
Schond L. Greenway CFO June 10, 2021 P 1,652 0 0 $0
Mariam E Morris Chief Financial Officer Aug. 17, 2016 A 0 0 $0
Robert Moscato Jr. COO Dec. 4, 2017 P 2,592,743 0 0 $0
Paul Varki Chief Legal Officer June 10, 2026 F 32,576 0 0 $0
Stephen Smolinski Chief Commercial Officer Jan. 4, 2022 A 0 0 $0
Jeffrey H Wilkins Chief Medical Officer June 10, 2021 P 27,002 0 0 $0
James Archie Harrell Jr Chief Commercial Officer June 10, 2021 P 35,673 0 0 $0
Simon Pedder Executive Chairman of the Bd June 28, 2019 A 0 0 $0
Ronald Marcus Chief Medical Officer Aug. 17, 2016 A 36,000 0 0 $0
John Joseph Kaiser Chief Business Officer Aug. 17, 2016 A 0 0 $0
Ron M Philip Director June 30, 2026 A 0 0 $0
Rita Jain Director June 30, 2026 A 0 0 $0
Kevin Robert Lind Director June 30, 2026 A 0 0 $0
Samantha Truex Director June 2, 2026 A 0 0 $0
Aaron Kantoff Director June 2, 2026 A 0 0 $0
Michael Thomas Heffernan Director June 2, 2026 A 0 0 $0
Gilla Kaplan Director June 2, 2026 A 6,333 0 0 $0
Joseph M Miller Director Dec. 31, 2021 A 40,582 0 0 $0
Magnus Persson Director Dec. 31, 2021 A 0 0 $0
June Sherie Almenoff Director Dec. 31, 2021 A 0 0 $0
Sol J Barer Director June 15, 2021 A 0 0 $0
Uli Hacksell Director June 28, 2019 A 0 0 $0
Keith Schmidt Director June 11, 2019 A 0 0 $0
Isaac Blech Director Dec. 31, 2017 A 385,452 0 0 $0
Randal Jones Director Nov. 17, 2017 A 0 0 $0
Thomas H Aasen Director Sept. 30, 2016 A 0 0 $0
Eugene A Bauer Director Sept. 30, 2016 A 0 0 $0
Behshad Sheldon Director May 18, 2016 A 0 0 $0
Anthony A. Florence, Jr. 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Peter W. Sonsini 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Ravi Viswanathan 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Harry R Weller 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Forest Baskett 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Krishna Kittu Kolluri 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Scott D. Sandell 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Patrick J. Kerins 10% owner Oct. 20, 2015 C 594,245 0 0 $0
David M Mott 10% owner Oct. 20, 2015 C 594,245 0 0 $0
James M Barrett 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Peter J Barris 10% owner Oct. 20, 2015 C 594,245 0 0 $0
Jennifer Riley Aug. 11, 2026 S 37,041 0 1 $-52,011
Mittie Doyle Aug. 10, 2026 M 51,776 0 5 $-163,624
Michael F Cola July 1, 2021 A 175,746 0 0 $0
Phil Gutry June 30, 2021 A 0 0 $0
Suzanne Louise Bruhn June 30, 2021 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 4 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Armistice Capital, LLC, Steven Boyd ×28 filings June 28, 2023 Initial filing Passive investment SEC
Fremantle, LLC (fka Fremantle Corporation) 1, Randal Jones Oct. 18, 2018 Initial filing Passive investment SEC
LRS International, LLC, Robert Moscato, Jr. ×2 filings Oct. 18, 2018 Initial filing Passive investment SEC
Fremantle Corporation, Randal Jones Nov. 27, 2017 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 15 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
MEDI · Harbor ETF Trust 0.50% 10,218 NS April 30, 2026 N-PORT
IWC · iShares Trust 0.18% 142,127 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.03% 196,629 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.02% 1,071,150 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.02% 185,898 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 240,501 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.02% 17,926 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.02% 22,825 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.01% 537,095 SH Aug. 8, 2026 Daily
ITOT · iShares Trust 0.00% 80,307 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 11,077 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 9,276 NS April 30, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.00% 140 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 1,675,498 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 3,450 SH Aug. 8, 2026 Daily