Joseph Klein III
CIK 1206369 · View on SEC EDGAR ↗
Insider
First SEC filing: May 5, 2026 · Latest: May 5, 2026
On this page
Insider at
Insider transactions
0 buys (P)
14 sells (S)
Net:
$-9,356,036
+ 69 non-open-market transactions below
last 12 months, based on the transactions shown below
Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted
69 other filings hidden
| Date | Ticker | Code | Shares | Price | Value | Owned after | Δ own | A/D | vs now |
|---|---|---|---|---|---|---|---|---|---|
| July 1, 2026 | IONS | S 10b5-1 | 11,419 | $79.04 | $902,558 | 11,014 Direct | -50.90% | Disposed | -24.8% (price as of 2026-08-20) |
| July 1, 2026 | IONS | S 10b5-1 | 99 | $79.45 | $7,866 | 22,433 Direct | -0.44% | Disposed | -25.2% (price as of 2026-08-20) |
| May 1, 2026 | IONS | S 10b5-1 | 1,431 | $74.45 | $106,538 | 11,014 Direct | -11.50% | Disposed | -20.1% (price as of 2026-08-20) |
| May 1, 2026 | IONS | S 10b5-1 | 8,680 | $73.35 | $636,678 | 12,445 Direct | -41.09% | Disposed | -18.9% (price as of 2026-08-20) |
| April 1, 2026 | IONS | S 10b5-1 | 2,216 | $75.95 | $168,305 | 11,014 Direct | -16.75% | Disposed | -21.7% (price as of 2026-08-20) |
| April 1, 2026 | IONS | S 10b5-1 | 20,105 | $75.50 | $1,517,928 | 13,230 Direct | -60.31% | Disposed | -21.2% (price as of 2026-08-20) |
| March 3, 2026 | IONS | S 10b5-1 | 1,012 | $80.82 | $81,790 | 11,014 Direct | -8.42% | Disposed | -26.4% (price as of 2026-08-20) |
| March 3, 2026 | IONS | S 10b5-1 | 6,794 | $80.00 | $543,520 | 12,026 Direct | -36.10% | Disposed | -25.7% (price as of 2026-08-20) |
| March 3, 2026 | IONS | S 10b5-1 | 13,526 | $79.17 | $1,070,853 | 18,820 Direct | -41.82% | Disposed | -24.9% (price as of 2026-08-20) |
| Nov. 25, 2025 | IONS | S 10b5-1 | 4,000 | $80.00 | $320,000 | 0 Indirect | -100.00% | Disposed | -25.7% (price as of 2026-08-20) |
| Nov. 25, 2025 | IONS | S 10b5-1 | 4,000 | $80.00 | $320,000 | 0 Indirect | -100.00% | Disposed | -25.7% (price as of 2026-08-20) |
| Nov. 25, 2025 | IONS | S 10b5-1 | 4,000 | $80.00 | $320,000 | 0 Indirect | -100.00% | Disposed | -25.7% (price as of 2026-08-20) |
| Sept. 3, 2025 | IONS | S 10b5-1 | 28,000 | $60.00 | $1,680,000 | 0 Indirect | -100.00% | Disposed | -0.9% (price as of 2026-08-20) |
| Sept. 3, 2025 | IONS | S 10b5-1 | 28,000 | $60.00 | $1,680,000 | 0 Indirect | -100.00% | Disposed | -0.9% (price as of 2026-08-20) |
| July 16, 2024 | IONS | S 10b5-1 | 12,000 | $50.00 | $600,000 | 0 Indirect | -100.00% | Disposed | 18.9% (price as of 2026-08-20) |
| May 3, 2024 | IONS | S | 930 | $42.90 | $39,897 | 0 Indirect | -100.00% | Disposed | 38.6% (price as of 2026-08-20) |
| May 3, 2024 | IONS | S | 1,070 | $42.55 | $45,528 | 930 Indirect | -53.50% | Disposed | 39.7% (price as of 2026-08-20) |
| May 3, 2024 | IONS | S | 731 | $42.98 | $31,418 | 2,000 Indirect | -26.77% | Disposed | 38.3% (price as of 2026-08-20) |
| May 3, 2024 | IONS | S | 1,269 | $42.59 | $54,047 | 2,731 Indirect | -31.72% | Disposed | 39.6% (price as of 2026-08-20) |
| May 3, 2024 | IONS | S | 682 | $42.94 | $29,285 | 4,000 Indirect | -14.57% | Disposed | 38.5% (price as of 2026-08-20) |
| May 3, 2024 | IONS | S | 1,318 | $42.57 | $56,107 | 4,682 Indirect | -21.97% | Disposed | 39.7% (price as of 2026-08-20) |
| Nov. 15, 2023 | IONS | S 10b5-1 | 2,000 | $50.00 | $100,000 | 16,346 Direct | -10.90% | Disposed | 18.9% (price as of 2026-08-20) |
| Sept. 26, 2023 | IONS | S 10b5-1 | 2,000 | $45.13 | $90,260 | 18,346 Direct | -9.83% | Disposed | 31.8% (price as of 2026-08-20) |
| July 18, 2023 | IONS | S 10b5-1 | 3,555 | $42.00 | $149,310 | 20,346 Direct | -14.87% | Disposed | 41.6% (price as of 2026-08-20) |
| Jan. 17, 2023 | IONS | S 10b5-1 | 2,000 | $40.00 | $80,000 | 16,791 Direct | -10.64% | Disposed | 48.7% (price as of 2026-08-20) |
| July 15, 2022 | IONS | S 10b5-1 | 644 | $38.78 | $24,974 | 18,791 Direct | -3.31% | Disposed | 53.3% (price as of 2026-08-20) |
| July 15, 2022 | IONS | S 10b5-1 | 689 | $37.74 | $26,003 | 19,435 Direct | -3.42% | Disposed | 57.6% (price as of 2026-08-20) |
| July 15, 2021 | IONS | S 10b5-1 | 4,334 | $35.30 | $152,990 | 18,126 Direct | -19.30% | Disposed | 68.4% (price as of 2026-08-20) |
| Oct. 20, 2020 | IONS | S 10b5-1 | 2,889 | $46.86 | $135,379 | 13,794 Direct | -17.32% | Disposed | 26.9% (price as of 2026-08-20) |
| Dec. 23, 2019 | IONS | S 10b5-1 | 1,000 | $61.87 | $61,870 | 12,683 Direct | -7.31% | Disposed | -3.9% (price as of 2026-08-20) |
| Dec. 16, 2019 | IONS | S 10b5-1 | 1,000 | $65.45 | $65,450 | 12,683 Direct | -7.31% | Disposed | -9.2% (price as of 2026-08-20) |
Showing latest 100 of 396 transactions
P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding
Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.
Derivative holdings (Form 4 Table II)
Options, RSUs and convertible securities reported on Form 4 Table II.
| Date | Ticker | Security | Underlying | Exercise price | Expiration | Shares | A/D |
|---|---|---|---|---|---|---|---|
| July 1, 2026 | IONS | Restricted Stock Unit | Common Stock (2,301) | — | — | 2,301 | Acquired |
| July 1, 2026 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (5,369) | $79.19 | June 30, 2036 | 5,369 | Acquired |
| July 1, 2026 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (11,518) | $39.94 | June 30, 2035 | 11,518 | Disposed |
| May 1, 2026 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (10,111) | $47.11 | June 30, 2034 | 10,111 | Disposed |
| April 1, 2026 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (10,321) | $41.08 | July 2, 2033 | 10,321 | Disposed |
| April 1, 2026 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (12,000) | $38.06 | June 30, 2032 | 12,000 | Disposed |
| March 3, 2026 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (4,000) | $42.88 | July 1, 2028 | 4,000 | Disposed |
| March 3, 2026 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (12,000) | $40.05 | June 30, 2031 | 12,000 | Disposed |
| Nov. 25, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (4,000) | $60.20 | June 30, 2030 | 4,000 | Disposed |
| Nov. 25, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (4,000) | $60.20 | June 30, 2030 | 4,000 | Disposed |
| Nov. 25, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (4,000) | $60.20 | June 30, 2030 | 4,000 | Disposed |
| Sept. 3, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (16,000) | $52.22 | July 2, 2027 | 16,000 | Disposed |
| Sept. 3, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (12,000) | $42.88 | July 1, 2028 | 12,000 | Disposed |
| Sept. 3, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (16,000) | $52.22 | July 2, 2027 | 16,000 | Disposed |
| Sept. 3, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (12,000) | $42.88 | July 1, 2028 | 12,000 | Disposed |
| July 1, 2025 | IONS | Restricted Stock Unit | Common Stock (5,220) | — | — | 5,220 | Acquired |
| July 1, 2025 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (11,518) | $39.94 | June 30, 2035 | 11,518 | Acquired |
| July 16, 2024 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (12,000) | $24.42 | June 30, 2026 | 12,000 | Disposed |
| July 1, 2024 | IONS | Restricted Stock Unit | Common Stock (4,079) | — | — | 4,079 | Acquired |
| July 1, 2024 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (10,111) | $47.11 | June 30, 2034 | 10,111 | Acquired |
| July 17, 2023 | IONS | Restricted Stock Unit | Common Stock (5,333) | — | — | 5,333 | Disposed |
| July 17, 2023 | IONS | Restricted Stock Unit | Common Stock (1,777) | — | — | 1,777 | Disposed |
| July 3, 2023 | IONS | Restricted Stock Unit | Common Stock (4,677) | — | — | 4,677 | Acquired |
| July 3, 2023 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (10,321) | $41.08 | July 2, 2033 | 10,321 | Acquired |
| July 15, 2022 | IONS | Restricted Stock Unit | Common Stock (2,665) | — | — | 2,665 | Disposed |
| July 15, 2022 | IONS | Restricted Stock Unit | Common Stock (5,333) | — | — | 5,333 | Disposed |
| July 1, 2022 | IONS | Restricted Stock Unit | Common Stock (5,333) | — | — | 5,333 | Acquired |
| July 1, 2022 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (12,000) | $38.06 | June 30, 2032 | 12,000 | Acquired |
| July 15, 2021 | IONS | Restricted Stock Unit | Common Stock (5,333) | — | — | 5,333 | Disposed |
| July 15, 2021 | IONS | Restricted Stock Unit | Common Stock (889) | — | — | 889 | Disposed |
| July 15, 2021 | IONS | Restricted Stock Unit | Common Stock (666) | — | — | 666 | Disposed |
| July 15, 2021 | IONS | Restricted Stock Unit | Common Stock (1,778) | — | — | 1,778 | Disposed |
| July 1, 2021 | IONS | Restricted Stock Unit | Common Stock (5,333) | — | — | 5,333 | Acquired |
| July 1, 2021 | IONS | Non-Qualified Stock Option (right to buy) | Common Stock (12,000) | $40.05 | June 30, 2031 | 12,000 | Acquired |
| July 6, 2020 | IONS | Restricted Stock Units | Common Stock (667) | — | — | 667 | Disposed |
| July 2, 2020 | IONS | Restricted Stock Units | Common Stock (889) | — | — | 889 | Disposed |
| July 1, 2020 | IONS | Director Stock Option (right to buy) | Common Stock (12,000) | $60.20 | June 30, 2030 | 12,000 | Acquired |
| July 1, 2020 | IONS | Restricted Stock Units | Common Stock (5,333) | — | — | 5,333 | Acquired |
| July 1, 2020 | IONS | Restricted Stock Units | Common Stock (1,778) | — | — | 1,778 | Disposed |
| July 1, 2020 | IONS | Restricted Stock Units | Common Stock (666) | — | — | 666 | Disposed |
| Dec. 23, 2019 | IONS | Employee Stock Option (right to buy) | Common Stock (1,000) | $35.53 | June 30, 2024 | 1,000 | Disposed |
| Dec. 16, 2019 | IONS | Employee Stock Option (right to buy) | Common Stock (1,000) | $35.53 | June 30, 2024 | 1,000 | Disposed |
| Dec. 9, 2019 | IONS | Employee Stock Option (right to buy) | Common Stock (1,000) | $35.53 | June 30, 2024 | 1,000 | Disposed |
| Dec. 2, 2019 | IONS | Employee Stock Option (right to buy) | Common Stock (1,000) | $35.53 | June 30, 2024 | 1,000 | Disposed |
| July 3, 2019 | IONS | Restricted Stock Units | Common Stock (667) | — | — | 667 | Disposed |
| July 2, 2019 | IONS | Restricted Stock Units | Common Stock (889) | — | — | 889 | Disposed |
| July 1, 2019 | IONS | Restricted Stock Units | Common Stock (7,110) | — | — | 7,110 | Acquired |
| July 1, 2019 | IONS | Director Stock Option (right to buy) | Common Stock (16,000) | $64.80 | June 30, 2029 | 16,000 | Acquired |
| July 1, 2019 | IONS | Restricted Stock Units | Common Stock (667) | — | — | 667 | Disposed |
| July 1, 2019 | IONS | Restricted Stock Units | Common Stock (666) | — | — | 666 | Disposed |
| July 3, 2018 | IONS | Restricted Stock Units | Common Stock (667) | — | — | 667 | Disposed |
| July 2, 2018 | IONS | Director Stock Option (right to buy) | Common Stock (16,000) | $42.88 | July 1, 2028 | 16,000 | Acquired |
| July 2, 2018 | IONS | Restricted Stock Units | Common Stock (3,555) | — | — | 3,555 | Acquired |
| July 1, 2018 | IONS | Restricted Stock Units | Common Stock (2,000) | — | — | 2,000 | Disposed |
| March 29, 2018 | IONS | Employee Stock Option (right to buy) | Common Stock (2,000) | $24.42 | June 30, 2026 | 2,000 | Acquired |
| March 15, 2018 | IONS | Employee Stock Option (right to buy) | Common Stock (2,000) | $24.42 | June 30, 2026 | 2,000 | Acquired |
| Feb. 28, 2018 | IONS | Employee Stock Option (right to buy) | Common Stock (3,000) | $35.53 | June 30, 2024 | 3,000 | Acquired |
| Feb. 15, 2018 | IONS | Employee Stock Option (right to buy) | Common Stock (3,000) | $35.53 | June 30, 2024 | 3,000 | Acquired |
| Jan. 30, 2018 | IONS | Employee Stock Option (right to buy) | Common Stock (3,000) | $35.53 | June 30, 2024 | 3,000 | Acquired |
| Jan. 16, 2018 | IONS | Employee Stock Option (right to buy) | Common Stock (3,000) | $35.53 | June 30, 2024 | 3,000 | Disposed |
| Dec. 29, 2017 | IONS | Non-Employee Director Stock Option (right to buy) | Common Stock (3,000) | $28.47 | June 30, 2023 | 3,000 | Disposed |
| Dec. 15, 2017 | IONS | NonEmployee Director stock option (right to buy) | Common Stock (3,000) | $28.47 | June 30, 2023 | 3,000 | Disposed |
| Nov. 30, 2017 | IONS | Director Stock Option (right to buy) | Common Stock (3,000) | $28.47 | June 30, 2023 | 3,000 | Disposed |
| Nov. 16, 2017 | IONS | Non-Employee Director Stock Option (right to buy) | Common Stock (2,812) | $12.94 | July 1, 2022 | 2,812 | Disposed |
| Nov. 15, 2017 | IONS | Non-Employee Director Stock Option (right to buy) | Common Stock (2,250) | $28.47 | June 30, 2023 | 2,250 | Disposed |
| July 3, 2017 | IONS | Director Stock Option (right to buy) | Common Stock (16,000) | $52.22 | July 2, 2027 | 16,000 | Acquired |
| July 3, 2017 | IONS | Restricted Stock Units | Common Stock (2,667) | — | — | 2,667 | Acquired |
| July 1, 2017 | IONS | Restricted Stock Units | Common Stock (2,469) | — | — | 2,469 | Disposed |
| July 2, 2016 | IONS | Restricted Stock Units | Common Stock (312) | — | — | 312 | Disposed |
| July 1, 2016 | IONS | Director Stock Option (right to buy) | Common Stock (16,000) | $24.42 | June 30, 2026 | 16,000 | Acquired |
| July 1, 2016 | IONS | Restricted Stock Units | Common Stock (2,667) | — | — | 2,667 | Acquired |
| July 1, 2016 | IONS | Restricted Stock Units | Common Stock (1,803) | — | — | 1,803 | Disposed |
| Nov. 11, 2015 | IONS | Director Stock Option (right to buy) | Common Stock (3,125) | $12.94 | July 1, 2022 | 3,125 | Disposed |
| Nov. 11, 2015 | IONS | Director Stock Option (right to buy) | Common Stock (3,750) | $9.30 | June 30, 2021 | 3,750 | Disposed |
| July 2, 2015 | IONS | Restricted Stock Units | Common Stock (312) | — | — | 312 | Disposed |
| July 1, 2015 | IONS | Director Stock Option (right to buy) | Common Stock (16,000) | $57.16 | June 30, 2025 | 16,000 | Acquired |
| July 1, 2015 | IONS | Restricted Stock Units | Common Stock (2,667) | — | — | 2,667 | Acquired |
| July 1, 2015 | IONS | Restricted Stock Units | Common Stock (667) | — | — | 667 | Disposed |
| July 1, 2015 | IONS | Restricted Stock Units | Common Stock (469) | — | — | 469 | Disposed |
| March 5, 2015 | IONS | Director Stock Option (right to buy) | Common Stock (2,500) | $12.94 | July 1, 2022 | 2,500 | Disposed |
| March 5, 2015 | IONS | Director Stock Option (right to buy) | Common Stock (3,750) | $9.30 | June 30, 2021 | 3,750 | Disposed |
| March 5, 2015 | IONS | Director Stock Option (right to buy) | Common Stock (3,750) | $9.22 | June 30, 2020 | 3,750 | Disposed |
| July 2, 2014 | IONS | Restricted Stock Units | Common Stock (313) | — | — | 313 | Disposed |
| July 1, 2014 | IONS | Director Stock Option (right to buy) | Common Stock (16,000) | $35.53 | June 30, 2024 | 16,000 | Acquired |
| July 1, 2014 | IONS | Restricted Stock Units | Common Stock (2,667) | — | — | 2,667 | Acquired |
| July 1, 2014 | IONS | Restricted Stock Units | Common Stock (469) | — | — | 469 | Disposed |
| Jan. 24, 2014 | IONS | Director Stock Option (right to buy) | Common Stock (2,813) | $12.94 | July 1, 2022 | 2,813 | Disposed |
| Jan. 24, 2014 | IONS | Director Stock Option (right to buy) | Common Stock (7,500) | $16.32 | June 30, 2019 | 7,500 | Disposed |
| Aug. 9, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (7,500) | $9.30 | June 30, 2021 | 7,500 | Disposed |
| Aug. 9, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (7,500) | $9.22 | June 30, 2020 | 7,500 | Disposed |
| Aug. 9, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (3,750) | $13.88 | June 30, 2018 | 3,750 | Disposed |
| July 2, 2013 | IONS | Restricted Stock Units | Common Stock (313) | — | — | 313 | Disposed |
| July 1, 2013 | IONS | Restricted Stock Units | Common Stock (1,875) | — | — | 1,875 | Acquired |
| July 1, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (11,250) | $28.47 | June 30, 2023 | 11,250 | Acquired |
| March 20, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (3,750) | $13.88 | June 30, 2018 | 3,750 | Disposed |
| March 20, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (4,166) | $9.77 | July 1, 2017 | 4,166 | Disposed |
| March 20, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (2,500) | $16.32 | June 30, 2019 | 2,500 | Disposed |
| March 19, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (3,726) | $5.93 | July 2, 2016 | 3,726 | Disposed |
| March 19, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (3,726) | $5.93 | July 2, 2016 | 3,726 | Disposed |
| March 19, 2013 | IONS | Director Stock Option (right to buy) | Common Stock (3,727) | $5.93 | July 2, 2016 | 3,727 | Disposed |
Showing latest 100 of 163 transactions
Exercise/conversion price is blank when not applicable (e.g. RSUs).
Initial ownership (Form 3) 2 holdings
Securities held when first becoming an insider, per SEC Form 3.