BMRN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $55.75
Market Cap (MRQ) $10.79B
P/E (TTM) 142.9
EPS (TTM) $0.39
Revenue (TTM) $3.41B
ROE (TTM) 1.2%
Debt/Equity (MRQ) 0.7
52W Range $49–$71

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About BioMarin Pharmaceutical Inc. - Common Stock Company overview from Wikipedia

05 · wikidata

BioMarin Pharmaceutical Inc. is an American biotechnology company headquartered in San Rafael, California. It has offices and facilities in the United States, South America, Asia, and Europe. BioMarin's core business and research are in enzyme replacement therapies (ERTs). BioMarin was the first company to provide therapeutics for mucopolysaccharidosis type I (MPS I), by manufacturing laronidase (Aldurazyme, commercialized by Genzyme Corporation). BioMarin was also the first company to provide therapeutics for phenylketonuria (PKU).

Over the years, BioMarin has been criticised for drug pricing and for specific instances of denying access to drugs in clinical trials.

History

BioMarin was founded in 1997 by Christopher Starr Ph.D. and Grant W. Denison Jr. with an investment of a $1.5 million from Glyko Biomedical and went public in 1999. Seed investors were amongst others MPM Bioventures, Grosvenor Fund and Florian Schönharting.

Business development

In 2002, BioMarin acquired Glyko Biomedical. In 2009, BioMarin acquired Huxley Pharmaceuticals, Inc. (Huxley), which had rights to a proprietary form of 3,4-diaminopyridine (3,4-DAP), amifampridine phosphate. In 2010, BioMarin was granted marketing approval by the European Commission for 3,4-diaminopyridine (3,4-DAP), amifampridine phosphate for the treatment of the rare autoimmune disease Lambert–Eaton myasthenic syndrome (LEMS). BioMarin launched the product under the name Firdapse.

In 2010, BioMarin acquired LEAD Therapeutics, Inc. (LEAD), a small private drug discovery and early stage development company with key compound LT-673, an orally available poly (ADP-ribose) polymerase (PARP) inhibitor studied for the treatment of patients with rare, genetically defined cancers. This acquisition was followed by the purchase of ZyStor Therapeutics, Inc. (ZyStor), a privately held biotechnology company developing ERTs for the treatment of lysosomal storage disorders and its lead product candidate, ZC-701, a fusion of insulin-like growth factor 2 and alpha glucosidase (IGF2-GAA) in development for Pompe disease. At its R&D day in October 2010, BioMarin also announced a new program for a peptide therapeutic, vosoritide (BMN-111), for the treatment of achondroplasia.

In 2012, BioMarin acquired Zacharon Pharmaceuticals, a private biotechnology company based in San Diego focused on developing small molecules targeting pathways of glycan metabolism. In 2014, BioMarin acquired a histone deacetylase inhibitor chemical library from Repligen for $2 million with the intention of advancing work toward therapies for Friedreich's ataxia and other neurological disorders. In November 2014, the company agreed to the acquisition of Prosensa for up to $840 million; however, the range of treatments for Duchenne muscular dystrophy failed to attain FDA approval, and development ceased in May 2016. In October 2019 it was revealed that the group will open an office in Dublin to support further growth through Europe, the Middle East and Asia. In December 2025, BioMarin agreed to acquire Amicus Therapeutics for $4.8 billion.

Acquisition history

The following is an illustration of the company's major mergers and acquisitions and historical predecessors (this is not a comprehensive list):

Products

As of 2022, BioMarin has six products on the market, each of which is an orphan drug.

Tetrahydrobiopterin (branded as Kuvan) (sapropterin dihydrochloride), a small molecule drug for phenylketonuria, introduced in 2007 as the first medication-based intervention to treat phenylketonuria

Arylsulfatase B (branded as Naglazyme) (galsulfase), a recombinant protein therapeutic for Maroteaux–Lamy syndrome (also called mucopolysaccharidosis type VI)

Iduronidase (branded as Aldurazyme), a recombinant protein therapeutic for mucopolysaccharidosis I

Amifampridine (branded as Firdapse), a small molecule drug for Lambert–Eaton myasthenic syndrome (as of 2013 approved in the EU only)

Elosulfase alfa (branded as Vimizim), is the only enzyme replacement therapy to address the cause of Morquio A Syndrome (MPS IVA), which affects an estimated 3,000 patients in the developed world. The disease occurs as a result of a deficiency of activity in an enzyme involved in glycosaminoglycan (GAG) metabolism.

Cerliponase alfa (branded as Brineura), is an enzyme replacement treatment for Batten disease, which is a form of neuronal ceroid lipofuscinosis. It was approved in 2017.

Valoctocogene roxaparvovec (branded as Roctavian) is an adeno-associated viral vector for treatment of hemophilia A that aims to transfer a working copy of the Factor VIII gene into patients who lack one. It was approved in the EU in August 2022.

Biomarin is working to develop several new drugs.

Controversies

In 2010, BioMarin became involved in controversy surrounding 3,4-diaminopyridine (3,4-DAP). BioMarin markets a phosphate salt of 3,4-DAP under the name Firdapse. In 2010, BioMarin was granted exclusive licensing rights to Firdapse for 10 years. As a result, the price of a prescribed National Health Service treatment course has increased from $1,987 for the unlicensed drug to $69,970 for Firdapse. The company states that prior to its licensing, there was no guaranteed quality control of the product and no way of formally monitoring for uncommon side effects through the regulatory process.

In 2013, BioMarin Pharmaceuticals was at the center of a high-profile debate regarding expanded access of cancer patients to experimental drugs. On the advice of her doctor, Andrea Sloan, a patient with advanced ovarian cancer, requested that the company provide her with access to BMN 673, an unapproved PARP inhibitor drug candidate that had exhibited promising activity in a small Phase 1 clinical trial. The company declined, citing safety concerns. Ms. Sloan eventually received a similar drug candidate from a different company.

In 2015, there was another controversy over expanded access, concerning the supply of a drug on clinical trial to a German child who was suffering from a brain disorder but who was not part of the trial.

In April 2019, the BBC reported that patients who took part in a trial treatment for the drug Kuvan (sapropterin hydrochloride) were later denied access to it. The company was criticised by the NHS and Stephen Hammond MP for patient profiteering. The company commented the following in response: "BioMarin is disappointed that the NHS England has not recognised the value of treating PKU patients with Kuvan, despite more than a decade of positive patient outcomes across 26 countries in Europe, Russia and Turkey"

In June 2019, a Belgian court ordered BioMarin to continue supplying Vimizim to a young girl suffering from Morquio syndrome free of charge. BioMarin stopped providing free Vimizim at the beginning of the year after negotiations with Belgian health authorities regarding reimbursement of the product repeatedly failed. This caused the parents to start legal proceedings to force the company to keep providing the medicine free of charge. BioMarin was ordered in a preliminary injunction to keep doing so until a definitive judgment would be rendered, or until the medicine would be available on the Belgian market at a reasonable price.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

sectorHealthcare industryBiotechnology employees3,221 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$3.22B
2016-12-31 → 2025-12-31
EPS$1.80
2016-12-31 → 2025-12-31
Free Cash Flow$725M
2016-12-31 → 2025-12-31
Net margin2.1%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend BMRN 5Y avg Peer Median Verdict
P/E (TTM) 142.95Y avg ≈11.8 ≈11.8 35.7 Overvalued
P/S (TTM) 3.25Y avg ≈6.7 ≈6.7 9.7 Undervalued
P/B (MRQ) 1.75Y avg ≈3.2 ≈3.2 7.2 Undervalued
Price / FCF (TTM) 14.65Y avg ≈152.1 ≈152.1 · ·
Price / Cash Flow (TTM) 12.65Y avg ≈62.6 ≈62.6 16.0 Fair value
Price / Tangible Book (MRQ) 7.55Y avg ≈3.5 ≈3.5 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -38.2%
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 3, 2026 $0.73 $0.70 4.0%
March 31, 2026 $0.54 $0.77 -29.5%
Dec. 31, 2025 $-0.24 $0.64 -137.7%
Sept. 30, 2025 $-0.16 $0.38 -142.2%
June 30, 2025 $1.23 $0.85 44.4%
March 31, 2025 $0.95 $0.72 31.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 16
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $3.22B$2.85B$2.42B$2.10B$1.85B$1.86B$1.70B$1.49B$1.31B$1.12B$890M$749M
Cost of Revenue $717M$580M$532M$503M$471M$524M$359M$315M$242M$210M$152M$122M
R&D Expense $922M$747M$747M$650M$629M$628M$715M$696M$611M$662M$635M$462M
SG&A Expense $1.15B$1.01B$892M$823M$759M$738M$681M$604M$554M$477M$402M$302M
Operating Expenses $2.81B$2.37B$2.23B$1.94B$1.93B$1.90B$1.80B$1.61B$1.33B$1.92B$1.00B$842M
Operating Income $409M$484M$186M$161M$-82M$-43M$-100M$-124M$-15M$-803M$-111M$-93M
Interest Expense ··$17M$16M$15M$29M$23M$44M$43M$39M$38M$37M
Interest Income $75M$75M$58M$18M$10M$17M$23M$23M$15M$7M$5M$6M
Pretax Income $482M$542M$189M$150M$-75M$-49M$-95M$-143M$-36M$-831M$-155M$-125M
Income Tax $134M$115M$21M$8M$-11M$-903M$-71M$-65M$81M$-201M$17M$9M
Net Income $349M$427M$168M$142M$-64M$854M$-24M$-77M$-117M$-630M$-172M$-134M
EPS (Basic) $1.82$2.25$0.89$0.76$-0.35$4.72$-0.13$-0.44$-0.67$-3.80$-1.07$-0.92
EPS (Diluted) $1.80$2.21$0.87$0.75$-0.35$4.50$-0.13$-0.44$-0.67$-3.81$-1.07$-0.92
Shares (Basic) 191,787,000190,027,000187,834,000185,266,000182,852,000180,804,000179,039,000177,061,000174,427,000165,985,000160,025,000146,349,000
Shares (Diluted) 197,394,000196,708,000191,595,000188,963,000182,852,000191,678,000179,039,000177,268,000174,427,000166,219,000160,025,000146,349,000
EBITDA $489M$581M$262M$252M$26M$68M$5M$-28M$73M$-707M$-64M$-93M
Balance Sheet 28
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $1.31B$943M$755M$725M$587M$649M$437M$494M$598M$408M$397M$875M
Short-term Investments ········$798M$381M$196M$70M
Receivables $908M$661M$634M$461M$373M$448M$377M$343M$261M$215M$165M$144M
Inventory $1.30B$1.23B$1.11B$894M$777M$699M$680M$531M$476M$355M$272M$199M
Prepaid Expense ··········$28M$35M
Other Current Assets $186M$202M$141M$105M$110M$130M$131M$98M$74M$62M$60M$109M
Current Assets $3.95B$3.23B$2.96B$2.75B$2.27B$2.34B$1.94B$2.06B$2.21B$1.42B$1.09B$1.40B
PP&E (Net) $953M$1.04B$1.07B$1.07B$1.04B$1.03B$1.01B$949M$897M$799M$704M$524M
PP&E (Gross) $2.03B$1.93B$1.93B$1.88B$1.76B$1.67B$1.56B$1.42B$1.30B$1.14B$983M$752M
Accum. Depreciation $1.07B$892M$867M$802M$721M$636M$549M$473M$407M$343M$279M$229M
Goodwill $196M$196M$196M$196M$196M$196M$197M$197M$197M$197M$197M$54M
Intangibles $214M$255M$295M$339M$389M$417M$457M$492M$518M$554M$684M$157M
Other Non-current Assets $277M$251M$172M$176M$152M$142M$122M$37M$30M$33M$409M$55M
Total Assets $7.59B$6.99B$6.84B$6.38B$6.00B$5.85B$4.69B$4.43B$4.63B$4.02B$3.73B$2.48B
Accounts Payable $759M$607M$683M$573M$498M$493M$571M$437M$402M$371M$393M$232M
Accrued Liabilities ···········$98M
Current Liabilities $759M$607M$1.18B$589M$546M$493M$933M$523M$817M$439M$445M$236M
Capital Leases $37M$31M$38M$26M$32M$40M$44M·····
Deferred Tax ·········$0$144M·
Other Non-current Liabilities $151M$129M$120M$100M$98M$114M$98M$59M$59M$42M$45M$30M
Total Liabilities $1.51B$1.33B$1.89B$1.77B$1.74B$1.74B$1.57B$1.46B$1.82B$1.26B$1.33B$947M
Long-term Debt $597M···········
Common Stock $192.0K$191.0K$189.0K$186.0K$184.0K$182.0K$180.0K$178.0K$176.0K$173.0K$162.0K$149.0K
Retained Earnings $154M$-195M$-622M$-789M$-931M$-862M$-1.72B$-1.69B$-1.64B$-1.52B$-1.02B$-850M
AOCI $-13M$62M$-29M$-4M$14M$-16M$20M$5M$-23M$13M$21M$27M
Stockholders' Equity $6.09B$5.66B$4.95B$4.60B$4.27B$4.10B$3.12B$2.97B$2.81B$2.77B$2.40B$1.53B
Liabilities + Equity $7.59B$6.99B$6.84B$6.38B$6.00B$5.85B$4.69B$4.43B$4.63B$4.02B$3.73B$2.48B
Shares Outstanding 192,300,101190,761,000188,598,000186,251,000183,913,000181,741,000179,838,000178,252,954175,843,749172,647,588161,526,044149,093,647
Cash Flow 16
Metric Trend 202520242023202220212020201920182017201620152014
D&A $80M$96M$104M$102M$108M$105M$105M$96M$88M$97M$47M$46M
Stock-based Comp $181M$202M$207M$196M$197M$190M$160M$149M$140M$135M$112M$86M
Deferred Tax $49M$56M$-45M$-52M$-16M$-890M$-83M$-68M$44M$-228M$-77M$-26M
Amort. of Intangibles $19M$43M$62M$67M·······$10M
Other Non-cash $169M$-208M$-275M$-212M$79M$-180M$-110M$-79M$-164M$399M$-132M·
Operating Cash Flow $828M$573M$159M$176M$305M$85M$48M$20M$-9M$-228M$-219M$-70M
CapEx $103M$85M$97M$121M$96M$114M$145M$145M$199M$148M$228M$117M
Investing Cash Flow $-414M$136M$-111M$-20M$-366M$-54M$-31M$264M$-305M$-484M··
Stock Issued ·······$0$0$713M$888M$117M
Stock Repurchased ···$0$0$50M$0$0····
Net Stock Activity ···$0$0$-50M·$0$0$713M$888M$117M
Financing Cash Flow $-42M$-526M$-19M$-19M$-48.0K$181M$-75M$-388M$507M$727M··
Net Change in Cash $369M$188M$31M$137M$-62M$212M$-57M$-104M$190M$11M$-478M$307M
Taxes Paid $96M···········
Free Cash Flow $725M$487M$63M$55M$209M$-29M$-97M$-124M$-208M$-376M$-449M$-192M
Levered FCF ··$47M$40M$196M$566M$-103M$-148M$-347M$-406M$-492M$-232M
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 12.7%17.0%6.5%7.1%-4.5%-2.0%-5.9%-8.3%-1.1%-71.9%-12.4%-12.4%
Net Margin 10.8%15.0%6.9%6.8%-3.5%46.2%-1.4%-5.2%-8.9%-56.4%-19.3%-17.8%
Pretax Margin 15.0%19.0%7.8%7.1%-4.1%-2.3%-5.6%-9.6%-2.7%-74.4%-17.4%-16.6%
EBITDA Margin 15.2%20.3%10.8%12.0%1.4%3.7%0.28%-1.9%5.6%-63.3%-7.1%-12.4%
ROA 4.8%6.2%2.5%2.3%-1.1%16.3%-0.52%-1.7%-2.7%-16.3%-5.5%-5.7%
ROE 5.8%7.7%3.4%3.1%-1.5%21.1%-0.77%-2.6%-4.2%-24.4%-8.8%-9.3%
ROIC 4.9%6.7%2.8%3.1%-1.6%18.2%-0.81%-2.2%-1.7%-22.0%-5.1%-6.5%
Liquidity & Solvency 3
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 5.25.32.54.74.24.82.13.92.73.22.46.0
Quick Ratio 2.92.61.22.01.82.20.91.62.02.31.74.6
Interest Coverage ··9.19.4-5.4-1.3-4.3-2.8-0.3-20.3-2.9-2.5
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.40.40.40.30.30.40.40.30.30.30.30.3
Inventory Turnover 0.60.50.50.60.60.80.60.60.60.70.60.7
Receivables Turnover 4.14.44.45.04.54.54.74.95.55.95.85.7
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $31.65$29.66$26.25$24.71$23.22$22.59$17.36$16.65$15.97$16.02$14.86$10.25
Revenue / Share $16.32$14.51$12.63$11.09$10.10$9.71$9.52$8.41$7.53$6.72··
Cash Flow / Share $4.19$2.91$0.83$0.93$1.67$0.45$0.27$0.11$-0.05$-1.37··
Cash / Share $6.82$4.94$4.00$3.89$3.19$3.57$2.43$2.77$3.40$2.37$2.46$5.87
EPS (TTM) $1.80$2.21$0.87$0.75$-0.35$4.50$-0.13$-0.44$-0.67$-3.81$-1.07$-0.92
Growth Rates 9
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 12.9%18.0%15.4%13.5%-0.76%·······
Revenue CAGR 3Y 15.4%15.6%9.2%·········
Revenue CAGR 5Y 11.6%···········
EPS YoY -18.6%154.0%16.0%·········
EPS CAGR 3Y 33.9%·-42.2%·········
EPS CAGR 5Y -16.7%···········
Net Income YoY -18.3%154.6%18.4%·········
Net Income CAGR 3Y 35.1%·-41.9%·········
Net Income CAGR 5Y -16.4%···········
Valuation (TTM) 10
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $3.22B$2.85B$2.42B$2.10B$1.85B$1.86B$1.70B$1.49B$1.31B$1.12B$890M$749M
Net Income TTM $349M$427M$168M$142M$-64M$854M$-24M$-77M$-117M$-630M$-172M$-134M
Market Cap $11.43B$12.54B$18.18B$19.28B$16.25B$15.94B$15.21B$15.18B$15.68B$14.30B$16.92B$13.48B
P/E 33.029.7110.8138.0-252.419.5-650.4-193.5-133.1-21.7-97.9-98.3
P/S 3.54.47.59.28.88.68.910.211.912.819.018.0
P/B 1.92.23.74.23.83.94.95.15.65.27.08.8
P / Tangible Book 2.02.44.14.74.44.6······
P / Cash Flow 13.821.9114.2109.653.4186.7315.1751.1-1790.6-62.8-76.3-183.3
P / FCF 15.825.7290.6350.877.8-550.6-157.1-122.0-75.4-38.0-37.7-70.1
Earnings Yield 3.0%3.4%0.90%0.72%-0.40%5.1%-0.15%-0.52%-0.75%-4.6%-1.0%-1.0%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $3.22B $2.85B $2.42B $2.10B $1.85B
Operating Margin % 12.7% 17.0% 6.5% 7.1% -4.5%
Net Income $349M $427M $168M $142M $-64M
Diluted EPS $1.80 $2.21 $0.87 $0.75 $-0.35

Institutional owners (13F) 616 filers · $12.2B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 616
Value held $12.2B
New positions 89
Exited positions 75
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
89 (-16 vs prior Q) 75 (+9 vs prior Q) 209 (+1 vs prior Q) 199 (+30 vs prior Q) +10.2M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BlackRock, Inc. $1,169,875,004 20,445,212 9.56% Shares
VANGUARD GROUP INC $1,077,337,946 18,127,847 8.81% Shares
Dodge & Cox $849,426,895 14,844,930 6.94% Shares
PRIMECAP MANAGEMENT CO/CA/ $811,962,329 14,190,183 6.64% Shares
VANGUARD CAPITAL MANAGEMENT LLC $500,310,680 8,743,633 4.09% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $494,877,355 8,648,678 4.05% Shares
NORGES BANK $469,659,128 8,207,954 3.84% Shares
STATE STREET CORP $446,370,874 7,800,959 3.65% Shares
VIKING GLOBAL INVESTORS LP $435,819,735 7,616,563 3.56% Shares
Vestal Point Capital, LP $344,750,500 6,025,000 2.82% Shares
AQR CAPITAL MANAGEMENT LLC $322,537,038 5,699,541 2.64% Shares
FMR LLC $275,965,970 4,822,893 2.26% Shares
DIMENSIONAL FUND ADVISORS LP $233,217,034 4,075,714 1.91% Shares
GEODE CAPITAL MANAGEMENT, LLC $223,885,722 3,911,794 1.83% Shares
Capital Research Global Investors $200,521,024 3,504,387 1.64% Shares
Deep Track Capital, LP $189,254,063 3,307,481 1.55% Shares
MILLENNIUM MANAGEMENT LLC $118,549,312 2,071,816 0.97% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $92,468,664 1,616,020 0.76% Shares
FIRST TRUST ADVISORS LP $91,910,897 1,606,273 0.75% Shares
NORTHERN TRUST CORP $89,154,711 1,558,104 0.73% Shares
MORGAN STANLEY $86,115,553 1,504,989 0.70% Shares
Jones Hill Capital LP $81,915,580 1,431,590 0.67% Shares
Assenagon Asset Management S.A. $80,373,600 1,339,560 0.66% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $76,264,876 1,332,836 0.62% Shares
Swedbank AB $75,232,112 1,314,787 0.61% Shares
UBS Group AG $73,613,817 1,286,505 0.60% Shares
DNB Asset Management AS $72,566,061 1,268,194 0.59% Shares
Caisse de depot et placement du Quebec $70,749,440 1,236,446 0.58% Shares
VANGUARD FIDUCIARY TRUST CO $70,030,356 1,223,879 0.57% Shares
GOLDMAN SACHS GROUP INC $68,777,119 1,201,977 0.56% Shares
AMERIPRISE FINANCIAL INC $66,255,506 1,157,865 0.54% Shares
Bank of New York Mellon Corp $66,106,543 1,155,305 0.54% Shares
CITADEL ADVISORS LLC $64,224,186 1,122,408 0.52% Shares
Balyasny Asset Management L.P. $60,344,956 1,054,613 0.49% Shares
ARGA Investment Management, LP $59,474,983 1,039,409 0.49% Shares
Brandywine Global Investment Management, LLC $56,211,687 945,847 0.46% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $54,484,884 952,200 0.45% Call option
FRANKLIN RESOURCES INC $53,560,439 936,044 0.44% Shares
MACKENZIE FINANCIAL CORP $53,321,258 931,864 0.44% Shares
JANUS HENDERSON GROUP PLC $48,409,915 857,010 0.40% Shares
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $48,062,765 850,819 0.39% Shares
Hudson Bay Capital Management LP $47,206,614 825,002 0.39% Shares
Russell Investments Group, Ltd. $44,813,913 783,148 0.37% Shares
FORT WASHINGTON INVESTMENT ADVISORS INC /OH/ $42,723,120 712,052 0.35% Shares
LOOMIS SAYLES & CO L P $40,835,454 713,657 0.33% Shares
JPMORGAN CHASE & CO $40,573,267 694,550 0.33% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $39,869,980 696,784 0.33% Shares
Nuveen, LLC $39,432,077 689,131 0.32% Shares
EDMOND DE ROTHSCHILD HOLDING S.A. $39,311,857 687,030 0.32% Shares
Palo Alto Investors LP $39,068,500 682,777 0.32% Shares

Show all 616 institutional owners →

Activists & 5%+ owners 4 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
BioMarin Pharmaceutical Inc., BioMarin Falcons B.V., BioMarin Giants B.V. ×5 filings Feb. 2, 2015 · Initial filing · SEC
Millenco LLC, Integrated Core Strategies (US) LLC, Catapult Partners, Ltd., Catapult Capital Management LLC, Millennium International Management LP, Millennium International Management GP LLC, Millennium Management LLC, Israel A. Englander ×2 filings July 31, 2009 · Initial filing · SEC
June 6, 2005 · Initial filing Board campaign SEC
OrbiMed Advisors LLC, OrbiMed Capital LLC, Samuel D. Isaly, Richard B. Brewer, Joseph Klein, III ×2 filings May 6, 2005 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 50 insiders · 21 officers · 30 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Alexander Hardy Chief Executive Officer March 17, 2026 F 214,635 0 0 $0
Louis Drapeau Chief Executive Officer May 2, 2005 A 14,934 0 0 $0
Fredric D Price Chief Executive Officer May 6, 2004 P 79,285 0 0 $0
Brian Mueller EVP, Chief Financial Officer March 17, 2026 F 123,314 0 0 $0
Daniel K Spiegelman EVP, Chief Financial Officer April 30, 2019 A 47,686 0 0 $0
Jeffrey H Cooper SVP, Chief Financial Officer May 14, 2012 M 41,089 0 0 $0
Henry J Fuchs President, Worldwide R&D Sept. 13, 2024 F 185,074 0 0 $0
Robert Baffi President, Global Mfg/Tech Ops March 20, 2020 F 117,138 0 0 $0
Gregory R Friberg EVP, Chief R&D Officer Sept. 30, 2026 F 47,732 0 2 $-558,646
George Eric Davis EVP, Chief Legal Officer Sept. 2, 2026 S 61,003 0 2 $-2,762,781
Cristin Hubbard EVP, Chief Commercial Officer May 20, 2026 F 42,472 0 0 $0
Charles Greg Guyer EVP, Chief Technical Officer March 17, 2026 F 84,140 0 1 $-996,744
Rashmi Virendra Ramchandani VP, Chief Accounting Officer Jan. 20, 2026 A 25,610 0 0 $0
Erin Burkhart GVP, Chief Accounting Officer May 20, 2025 S 14,173 0 0 $0
Jeffrey Robert Ajer EVP, Chief Commercial Officer May 2, 2024 S 66,767 0 0 $0
Andrea Acosta GVP, Chief Accounting Officer July 16, 2021 F 18,122 0 0 $0
Steve Aselage EVP, Chief Business Officer July 2, 2012 M 59,030 0 0 $0
Emil D Kakkis Chief Medical Officer March 2, 2009 M 39,621 0 0 $0
Stuart J Swiedler SVP, Clinical Affairs July 7, 2008 A 12,000 0 0 $0
Christopher M Starr SVP, Chief Scientific Officer Dec. 1, 2005 M 295,176 0 0 $0
Jeffrey Landau SVP, Administration Oct. 31, 2004 A 2,740 0 0 $0
Robert M Plenge Director Sept. 10, 2026 A 6,140 0 0 $0
Elizabeth M Anderson Director June 2, 2026 A 41,940 0 0 $0
Barbara W. Bodem Director June 2, 2026 A 21,045 0 0 $0
Maykin Ho Director June 2, 2026 A 35,500 0 0 $0
Mark J Enyedy Director June 2, 2026 A 21,040 0 0 $0
Athena Countouriotis Director June 2, 2026 A 21,040 0 0 $0
Robert J. Hombach Director June 2, 2026 A 49,360 0 0 $0
Timothy P Walbert Director June 2, 2026 A 17,270 0 0 $0
Ian T Clark Director June 2, 2026 A 14,490 0 0 $0
Willard H Dere Director June 2, 2026 A 46,440 0 0 $0
Richard A Meier Director May 20, 2025 A 127,426 0 0 $0
Elaine J Heron Director June 3, 2024 M 97,720 0 0 $0
David E I Pyott Director May 21, 2024 A 49,750 0 0 $0
Jean Jacques Bienaime Director May 20, 2024 F 473,792 0 0 $0
Dennis Slamon Director March 18, 2024 M 31,299 0 0 $0
Mark J Alles Director May 23, 2023 A 15,095 0 0 $0
Bryan V Lawlis Director May 23, 2023 A 33,140 0 0 $0
Michael G Grey Director March 5, 2021 M 42,840 0 0 $0
Alan Lewis Director June 4, 2019 A 25,590 0 0 $0
Kathryn E Falberg Director July 15, 2016 A 2,640 0 0 $0
William D Young Director June 10, 2015 A 11,875 0 0 $0
Kenneth Bate Director June 10, 2015 A 11,875 0 0 $0
Pierre Lapalme Director June 10, 2015 A 31,250 0 0 $0
Joseph Klein III Director March 8, 2010 S 35,000 0 0 $0
Franz L Cristiani Director June 14, 2006 A · 0 0 $0
Erich Sager Director Feb. 24, 2006 M 3,309 0 0 $0
Gwynn Williams Director Nov. 30, 2004 A 812,565 0 0 $0
John Urquhart Director July 28, 2004 A · 0 0 $0
Mark Wood · May 22, 2013 M 20,277 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 85 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PBE · Invesco Exchange-Traded Fund Trust 2.32% 176,657 SH Oct. 23, 2026 Daily
BBP · ETFis Series Trust I 1.48% 24,255 NS July 31, 2026 N-PORT
HTEC · EXCHANGE TRADED CONCEPTS TRUST 1.31% 15,080 NS July 31, 2026 N-PORT
SRHQ · Elevation Series Trust 1.17% 41,384 NS July 31, 2026 N-PORT
RNIN · EA Series Trust 1.15% 35,050 NS July 31, 2026 N-PORT
IBB · iShares Trust 0.92% 1,454,497 SH Sept. 11, 2026 Daily
CALF · Pacer Funds Trust 0.79% 482,285 NS July 31, 2026 N-PORT
JOET · Virtus ETF Trust II 0.76% 30,936 NS July 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.73% 60,076 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.72% 14,556 SH Oct. 23, 2026 Daily
AFMC · First Trust Exchange-Traded Fund VI… 0.71% 23,122 NS Aug. 31, 2026 N-PORT
FXH · First Trust Exchange-Traded AlphaDE… 0.44% 77,415 NS July 31, 2026 N-PORT
IQSM · New York Life Investments ETF Trust 0.44% 24,133 NS July 31, 2026 N-PORT
QVMM · Invesco Exchange-Traded Fund Trust … 0.36% 26,512 SH Oct. 23, 2026 Daily
IVOG · VANGUARD ADMIRAL FUNDS 0.33% 108,709 SH Aug. 19, 2026 Daily
PTMC · Pacer Funds Trust 0.33% 21,272 NS July 31, 2026 N-PORT
DFSV · Dimensional ETF Trust 0.32% 436,803 NS July 31, 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 0.30% 2,559,860 SH Aug. 19, 2026 Daily
IVOO · VANGUARD ADMIRAL FUNDS 0.30% 312,378 SH Aug. 19, 2026 Daily
BKMC · BNY Mellon ETF Trust 0.28% 29,895 NS July 31, 2026 N-PORT
IVOV · VANGUARD ADMIRAL FUNDS 0.27% 71,381 SH Aug. 19, 2026 Daily
BBMC · J.P. Morgan Exchange-Traded Fund Tr… 0.25% 84,704 NS July 31, 2026 N-PORT
MIDU · Direxion Shares ETF Trust 0.25% 2,838 NS July 31, 2026 N-PORT
PWS · Pacer Funds Trust 0.20% 821 NS July 31, 2026 N-PORT
IYH · iShares Trust 0.20% 111,984 SH Sept. 11, 2026 Daily
SMMD · iShares Trust 0.17% 102,244 SH Sept. 11, 2026 Daily
FNY · First Trust Exchange-Traded AlphaDE… 0.17% 16,041 NS July 31, 2026 N-PORT
VFMF · VANGUARD WELLINGTON FUND 0.16% 19,998 SH Aug. 19, 2026 Daily
DFAS · Dimensional ETF Trust 0.16% 401,829 NS July 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.15% 84,531 NS July 31, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.15% 534,462 SH Aug. 19, 2026 Daily
ISCG · iShares Trust 0.15% 21,366 SH Sept. 11, 2026 Daily
DEUS · DBX ETF Trust 0.14% 6,578 NS Aug. 31, 2026 N-PORT
VFVA · VANGUARD WELLINGTON FUND 0.14% 20,990 SH Aug. 19, 2026 Daily
ESML · iShares Trust 0.13% 56,252 SH Sept. 11, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.13% 4,433,137 SH Aug. 19, 2026 Daily
IWS · iShares Trust 0.12% 286,469 SH Sept. 11, 2026 Daily
RWK · Invesco Exchange-Traded Fund Trust … 0.12% 28,178 SH Oct. 23, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.12% 2,217,617 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.11% 11,104 SH Sept. 11, 2026 Daily
FYEE · Fidelity Greenwood Street Trust 0.11% 3,901 NS July 31, 2026 N-PORT
PEXL · Pacer Funds Trust 0.09% 797 NS July 31, 2026 N-PORT
IWR · iShares Trust 0.09% 787,222 SH Sept. 11, 2026 Daily
EQAL · Invesco Exchange-Traded Fund Trust … 0.08% 11,498 SH Oct. 23, 2026 Daily
FNX · First Trust Exchange-Traded AlphaDE… 0.08% 18,000 NS July 31, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.06% 5,934 NS July 31, 2026 N-PORT
DFAT · Dimensional ETF Trust 0.06% 143,957 NS July 31, 2026 N-PORT
FBUF · Fidelity Greenwood Street Trust 0.05% 212 NS July 31, 2026 N-PORT
QARP · DBX ETF Trust 0.05% 614 NS Aug. 31, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.05% 4,814 NS July 31, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.05% 18,819 NS July 31, 2026 N-PORT
OMFL · Invesco Exchange-Traded Self-Indexe… 0.05% 40,633 SH Oct. 23, 2026 Daily
DFAC · Dimensional ETF Trust 0.04% 347,063 NS July 31, 2026 N-PORT
MNZL · EA Series Trust 0.04% 168 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.03% 19,135 NS July 31, 2026 N-PORT
IWD · iShares Trust 0.03% 425,477 SH Sept. 11, 2026 Daily
DSI · iShares Trust 0.03% 27,701 SH Sept. 11, 2026 Daily
REVS · Columbia ETF Trust I 0.03% 1,740 NS July 31, 2026 N-PORT
VONV · VANGUARD SCOTTSDALE FUNDS 0.03% 115,700 SH Aug. 19, 2026 Daily
DFUV · Dimensional ETF Trust 0.03% 74,321 NS July 31, 2026 N-PORT
TILT · FlexShares Trust 0.03% 9,322 NS July 31, 2026 N-PORT
PRF · Invesco Exchange-Traded Fund Trust 0.03% 45,169 SH Oct. 23, 2026 Daily
FHEQ · Fidelity Greenwood Street Trust 0.02% 3,375 NS July 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.02% 44,514 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.02% 6,143,206 SH Aug. 19, 2026 Daily
VONE · VANGUARD SCOTTSDALE FUNDS 0.02% 31,861 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.02% 16,031 SH Aug. 19, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.02% 43,345 SH Aug. 19, 2026 Daily
IUSG · iShares Trust 0.02% 97,914 SH Sept. 11, 2026 Daily
IWB · iShares Trust 0.02% 130,403 SH Sept. 11, 2026 Daily
IYY · iShares Trust 0.02% 8,059 SH Sept. 11, 2026 Daily
ITOT · iShares Trust 0.02% 253,576 SH Sept. 11, 2026 Daily
IUSV · iShares Trust 0.02% 71,403 SH Sept. 11, 2026 Daily
RECS · Columbia ETF Trust I 0.02% 16,398 NS July 31, 2026 N-PORT
IWV · iShares Trust 0.02% 51,240 SH Sept. 11, 2026 Daily
DFUS · Dimensional ETF Trust 0.02% 53,858 NS July 31, 2026 N-PORT
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.01% 169,270 SH Aug. 19, 2026 Daily
DFLV · Dimensional ETF Trust 0.00% 1,028 NS July 31, 2026 N-PORT
IJH · iShares Trust · 6,782,201 SH Sept. 11, 2026 Daily
IJK · iShares Trust · 638,802 SH Sept. 11, 2026 Daily
IJJ · iShares Trust · 423,789 SH Aug. 21, 2026 Daily
XJH · iShares Trust · 26,404 SH Sept. 8, 2026 Daily
ISCB · iShares Trust · 8,699 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 27,848 SH Sept. 11, 2026 Daily
SMMV · iShares Trust · 29,688 SH Aug. 19, 2026 Daily

BMRN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 35 analysts BUY
Median target $90.00 +61.4%
10 28.6% Strong Buy
17 48.6% Buy
8 22.9% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

27 analysts · 2026-10-24

Mean target $91.56 +64.2%

← Below all targets Current price $55.75
Low$60.00 Mean$91.56 High$122.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
BMRN $11.43B 33.0 12.9% 10.8% 5.8% ·
NBIX $14.20B 30.4 21.4% 16.7% 16.1% ·
HALO $7.93B 26.3 37.5% 22.7% 166.1% ·
BBIO $14.90B -20.2 126.3% -146.0% 41.2% ·
SMMT $13.56B -12.1 · · -235.1% ·
MDGL $13.30B -45.3 432.1% -30.1% -44.4% ·
PCVX $6.05B -8.2 · · -26.6% ·
KYMR $6.33B -21.1 -16.7% -794.0% -24.4% ·
KRYS $7.20B 36.0 33.9% 52.6% 18.1% ·

Latest News Recent headlines mentioning this company

23

Trading Signals Recent buy/sell signals with entry price and risk/reward ratio

25

No open signal right now — no card is filled, and that's honest.

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 6, 2026