Karen L. Smith
Insider
First SEC filing: May 28, 2020 · Latest: May 28, 2020
Insider at
Insider transactions
0 buys (P)
0 sells (S)
Net: $0
Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted
| Date | Ticker | Code | Shares | Price | Value | Owned after | Δ own | A/D | vs now |
|---|---|---|---|---|---|---|---|---|---|
| June 24, 2026 | CNTX | A | 45,000 | · | · | 45,000 Direct | · | Acquired | (price as of 2026-10-06) |
| March 31, 2026 | SKYE | A | 75,000 | · | · | 75,000 Direct | · | Acquired | (price as of 2026-10-06) |
| Feb. 6, 2026 | SKYE | A | 35,000 | · | · | 35,000 Direct | · | Acquired | (price as of 2026-10-06) |
| June 12, 2025 | CNTX | A | 123,500 | · | · | 123,500 Direct | · | Acquired | (price as of 2026-10-06) |
| Feb. 24, 2025 | SKYE | A | 35,000 | · | · | 35,000 Direct | · | Acquired | (price as of 2026-10-06) |
| Nov. 21, 2024 | AUPH | A | 12,135 | · | · | 24,807 Direct | +95.76% | Acquired | (price as of 2026-10-06) |
| Nov. 21, 2024 | AUPH | A | 18,641 | · | · | 18,641 Direct | · | Acquired | (price as of 2026-10-06) |
| Nov. 11, 2024 | AUPH | S | 5,241 | $8.43 | $44,182 | 12,672 Direct | -29.26% | Disposed | 86.1% (price as of 2026-10-06) |
| Nov. 8, 2024 | AUPH | M | 17,913 | · | · | 17,913 Direct | · | Acquired | (price as of 2026-10-06) |
| Nov. 8, 2024 | AUPH | M | 17,913 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-06) |
| Oct. 28, 2024 | SKYE | A | 70,000 | · | · | 70,000 Direct | · | Acquired | (price as of 2026-10-06) |
| Sept. 4, 2024 | CNTX | A | 19,315 | · | · | 19,315 Direct | · | Acquired | (price as of 2026-10-06) |
| July 2, 2024 | SKYE | A | 40,000 | · | · | 40,000 Direct | · | Acquired | (price as of 2026-10-06) |
| Aug. 18, 2023 | AUPH | A | 17,913 | · | · | 17,913 Direct | · | Acquired | (price as of 2026-10-06) |
| Aug. 18, 2023 | AUPH | A | 28,959 | · | · | 28,959 Direct | · | Acquired | (price as of 2026-10-06) |
| Feb. 1, 2023 | QNCX | A | 225,000 | · | · | 225,000 Direct | · | Acquired | (price as of 2026-10-06) |
| May 23, 2022 | QNCX | A | 1,365,449 | · | · | 1,365,449 Direct | · | Acquired | (price as of 2026-10-06) |
| May 19, 2022 | QNCX | A | 170,354 | · | · | 194,690 Direct | +700.01% | Acquired | (price as of 2026-10-06) |
| May 19, 2022 | QNCX | A | 151,799 | · | · | 151,799 Direct | · | Acquired | (price as of 2026-10-06) |
| May 19, 2022 | QNCX | A | 24,336 | · | · | 24,336 Direct | · | Acquired | (price as of 2026-10-06) |
| May 7, 2021 | EBS | F | 305 | $60.85 | $18,559 | 11,888 Direct | -2.50% | Disposed | -88.6% (price as of 2026-10-06) |
| Feb. 24, 2021 | EBS | A | 2,942 | · | · | 9,252 Direct | +46.62% | Acquired | (price as of 2026-10-06) |
| Feb. 24, 2021 | EBS | A | 2,941 | · | · | 12,193 Direct | +31.79% | Acquired | (price as of 2026-10-06) |
| Feb. 24, 2021 | EBS | A | 11,765 | $93.49 | $1,099,910 | 11,765 Direct | · | Acquired | -92.6% (price as of 2026-10-06) |
| March 5, 2018 | JAZZ | F | 648 | $143.39 | $92,917 | 28,474 Direct | -2.23% | Disposed | 61.4% (price as of 2026-10-06) |
| March 1, 2018 | JAZZ | A | 8,000 | · | · | 29,122 Direct | +37.88% | Acquired | (price as of 2026-10-06) |
| March 1, 2018 | JAZZ | A | 710 | · | · | 710 Direct | · | Acquired | (price as of 2026-10-06) |
| March 1, 2018 | JAZZ | A | 19,290 | · | · | 19,290 Direct | · | Acquired | (price as of 2026-10-06) |
| Feb. 26, 2018 | JAZZ | F | 525 | $147.44 | $77,406 | 21,122 Direct | -2.43% | Disposed | 56.9% (price as of 2026-10-06) |
| March 2, 2017 | JAZZ | A | 7,500 | · | · | 21,168 Direct | +54.87% | Acquired | (price as of 2026-10-06) |
| March 2, 2017 | JAZZ | A | 902 | · | · | 902 Direct | · | Acquired | (price as of 2026-10-06) |
| March 2, 2017 | JAZZ | A | 17,848 | · | · | 17,848 Direct | · | Acquired | (price as of 2026-10-06) |
| Feb. 27, 2017 | JAZZ | F | 571 | $136.97 | $78,210 | 13,668 Direct | -4.01% | Disposed | 68.9% (price as of 2026-10-06) |
| Aug. 12, 2016 | JAZZ | P 10b5-1 | 607 | $137.10 | $83,220 | 14,181 Direct | +4.47% | Acquired | 68.8% (price as of 2026-10-06) |
| Aug. 12, 2016 | JAZZ | P 10b5-1 | 1 | $137.26 | $137 | 14,182 Direct | +0.01% | Acquired | 68.6% (price as of 2026-10-06) |
| July 13, 2016 | JAZZ | P 10b5-1 | 580 | $143.63 | $83,305 | 13,574 Direct | +4.46% | Acquired | 61.1% (price as of 2026-10-06) |
| June 13, 2016 | JAZZ | P 10b5-1 | 557 | $149.61 | $83,333 | 12,994 Direct | +4.48% | Acquired | 54.7% (price as of 2026-10-06) |
| May 11, 2016 | JAZZ | F | 641 | $148.76 | $95,355 | 12,399 Direct | -4.92% | Disposed | 55.5% (price as of 2026-10-06) |
| April 13, 2016 | JAZZ | F | 103 | $147.34 | $15,176 | 13,040 Direct | -0.78% | Disposed | 57.0% (price as of 2026-10-06) |
| Feb. 25, 2016 | JAZZ | A | 6,000 | · | · | 13,143 Direct | +84.00% | Acquired | (price as of 2026-10-06) |
| Feb. 25, 2016 | JAZZ | A | 625 | · | · | 625 Direct | · | Acquired | (price as of 2026-10-06) |
| Feb. 25, 2016 | JAZZ | A | 14,375 | · | · | 14,375 Direct | · | Acquired | (price as of 2026-10-06) |
| May 11, 2015 | JAZZ | A | 6,830 | · | · | 6,830 Direct | · | Acquired | (price as of 2026-10-06) |
| May 11, 2015 | JAZZ | A | 275 | · | · | 7,105 Direct | +4.03% | Acquired | (price as of 2026-10-06) |
| May 11, 2015 | JAZZ | A | 2,264 | · | · | 2,264 Direct | · | Acquired | (price as of 2026-10-06) |
| May 11, 2015 | JAZZ | A | 15,516 | · | · | 15,516 Direct | · | Acquired | (price as of 2026-10-06) |
P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding
Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.
Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.
| Date | Ticker | Security | Underlying | Exercise price | Expiration | Shares | A/D |
|---|---|---|---|---|---|---|---|
| June 24, 2026 | CNTX | Stock Option (right to buy) | Common Stock | $0.58 | June 23, 2036 | 45,000 | Acquired |
| March 31, 2026 | SKYE | Stock Option (Right to Buy) | Common Stock | $0.62 | March 31, 2036 | 75,000 | Acquired |
| Feb. 6, 2026 | SKYE | Stock Option (Right to Buy) | Common Stock | $0.82 | Feb. 6, 2036 | 35,000 | Acquired |
| June 12, 2025 | CNTX | Stock Option (right to buy) | Common Stock | $0.65 | June 11, 2035 | 123,500 | Acquired |
| Feb. 24, 2025 | SKYE | Stock Option (Right to Buy) | Common Stock | $2.89 | Feb. 25, 2035 | 35,000 | Acquired |
| Nov. 21, 2024 | AUPH | Director Stock Option (right to buy) | Common Shares | $8.24 | Nov. 21, 2034 | 18,641 | Acquired |
| Nov. 8, 2024 | AUPH | Restricted Stock Units | Common Stock | · | · | 17,913 | Disposed |
| Oct. 28, 2024 | SKYE | Stock Option (Right to Buy) | Common Stock | $5.15 | Oct. 27, 2034 | 70,000 | Acquired |
| Sept. 4, 2024 | CNTX | Stock Option (right to buy) | Common Stock | $2.43 | Sept. 3, 2034 | 19,315 | Acquired |
| July 2, 2024 | SKYE | Director Stock Option (Right to Buy) | Common Stock | $7.56 | July 1, 2034 | 40,000 | Acquired |
| Aug. 18, 2023 | AUPH | Restricted Stock Units | Common Stock | · | · | 17,913 | Acquired |
| Aug. 18, 2023 | AUPH | Stock Option (right to buy) | Common Stock | $9.49 | Aug. 18, 2033 | 28,959 | Acquired |
| Feb. 1, 2023 | QNCX | Employee Stock Option (right to buy) | Common Stock | $0.94 | Jan. 31, 2033 | 225,000 | Acquired |
| May 23, 2022 | QNCX | Employee Stock Option (right to buy) | Common Stock | $2.98 | May 22, 2032 | 1,365,449 | Acquired |
| May 19, 2022 | QNCX | Employee Stock Option (right to buy) | Common Stock | $0.55 | March 27, 2032 | 151,799 | Acquired |
| Feb. 24, 2021 | EBS | Employee Stock Options (Right to Buy) | Common Stock | $93.49 | Feb. 23, 2028 | 11,765 | Acquired |
| March 1, 2018 | JAZZ | Incentive Stock Option (right to buy) | Ordinary Shares | $140.67 | Feb. 29, 2028 | 710 | Acquired |
| March 1, 2018 | JAZZ | Non-Qualified Stock Option (right to buy) | Ordinary Shares | $140.67 | Feb. 29, 2028 | 19,290 | Acquired |
| March 2, 2017 | JAZZ | Incentive Stock Option (right to buy) | Ordinary Shares | $136.18 | March 1, 2027 | 902 | Acquired |
| March 2, 2017 | JAZZ | Non-Qualified Stock Option (right to buy) | Ordinary Shares | $136.18 | March 1, 2027 | 17,848 | Acquired |
| Feb. 25, 2016 | JAZZ | Incentive Stock Option (right to buy) | Ordinary Shares | $123.36 | Feb. 24, 2026 | 625 | Acquired |
| Feb. 25, 2016 | JAZZ | Non-Qualified Stock Option (right to buy) | Ordinary Shares | $123.36 | Feb. 24, 2026 | 14,375 | Acquired |
| May 11, 2015 | JAZZ | Incentive Stock Option (right to buy) | Common Stock | $176.51 | May 10, 2025 | 2,264 | Acquired |
| May 11, 2015 | JAZZ | Non-Qualified Stock Option (right to buy) | Ordinary Shares | $176.51 | May 10, 2025 | 15,516 | Acquired |
Exercise/conversion price is blank when not applicable (e.g. RSUs).
Initial ownership (Form 3) 2 holdings
Securities held when first becoming an insider, per SEC Form 3.
Compensation (DEF 14A)
Matched by name from proxy statements (DEF 14A) — verify against the filing.
| Fiscal year | Salary | Bonus | Stock awards | Option awards | Non-equity incentive | Pension change | Other | Total |
|---|---|---|---|---|---|---|---|---|
| 2017 | $516,923 | · | $1,176,530 | $915,873 | $287,700 | · | $10,722 | $2,907,748 |
| 2016 | $496,154 | · | · | · | $245,000 | · | $4,695 | $2,087,805 |
| 2015 | $337,981 | $290,000 | · | · | $130,000 | · | $67,492 | $3,113,926 |
| Fiscal year | Salary | Bonus | Stock awards | Option awards | Non-equity incentive | Pension change | Other | Total |
|---|---|---|---|---|---|---|---|---|
| 2023 | $336,458 | · | $66,256 | · | · | · | $696,168 | $1,347,920 |
| 2022 | $273,734 | · | · | · | $115,208 | · | $4,000 | $3,485,274 |
Figures from the Summary Compensation Table of the company's proxy statement (DEF 14A). Compensation is not a recommendation.