SKYE Skye Bioscience, Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 14, 2026
$1.68
· of 52w range
· above low
· to high
$1.5052w low
$18.4052w high
Market Cap (MRQ)
$59M
P/E
-1.2
EPS
$-1.41
your badges
52W Range
$2–$18
Analyst Rating
BUY
Price Target
$68
P/E
-1.2
ROE
-175.6%
Net Profit Margin
·
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SKYE Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$1.68
Market Cap (MRQ)
$59M
P/E
-1.2
EPS
$-1.41
ROE
-175.6%
52W Range
$2–$18
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Stock splits
| Ex-date | Split | Type |
|---|---|---|
| Aug. 24, 2026 | 1-for-8 | Reverse |
| Sept. 8, 2023 | 1-for-250 | Reverse |
10-Year Performance Revenue, net income, margins and EPS trends
EPS$-1.412018-12-31 → 2025-12-31
Free Cash Flow$-43M2020-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | SKYE | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -1.25Y avg ≈-131.1 | ≈-131.1 | · | · | |
| P/B (MRQ) | -118.75Y avg ≈-34.5 | ≈-34.5 | · | · | |
| Price / FCF (TTM) | -1.55Y avg ≈-247.0 | ≈-247.0 | · | · | |
| Price / Cash Flow (TTM) | -1.55Y avg ≈-249.8 | ≈-249.8 | · | · | |
| Price / Tangible Book | 2.85Y avg ≈352.7 | ≈352.7 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | SKYE | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -110.7%5Y avg ≈-174.5% | ≈-174.5% | -96.7% | In line | |
| ROE | -175.6%5Y avg ≈3506.4% | ≈3506.4% | -138.9% | Below avg | |
| ROIC | -290.5%5Y avg ≈354.0% | ≈354.0% | -141.8% | Weak |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | SKYE | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 1.05Y avg ≈4.7 | ≈4.7 | 2.5 | Low liquidity | |
| Quick Ratio | 3.15Y avg ≈4.3 | ≈4.3 | 3.0 | Low liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-122.4%
Next Report
Nov 09, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 14, 2026 | $-1.55 | $-2.01 | 23.1% |
| March 31, 2026 | May 6, 2026 | $-2.56 | $-2.52 | -1.5% |
| Dec. 31, 2025 | $-2.88 | $-2.42 | -19.0% | |
| Sept. 30, 2025 | $-2.56 | $-2.71 | 5.6% | |
| June 30, 2025 | $-2.69 | $-0.32 | -746.7% | |
| March 31, 2025 | $-0.28 | $-0.29 | 4.3% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | · | · | · | $6M | $3M | $2M | $2M | $330.0K | |
| SG&A Expense | $16M | $18M | $8M | $6M | $5M | $4M | $4M | $4M | |
| Operating Expenses | $58M | $30M | $35M | $18M | $8M | $6M | $7M | $5M | |
| Operating Income | $-58M | $-30M | $-35M | $-18M | $-8M | $-6M | $-7M | $-5M | |
| Interest Expense | $0 | $749.3K | $906.3K | $665.1K | $769.2K | $706.4K | $1M | $94.8K | |
| Interest Income | $2M | $3M | $100.0K | $19.0K | $3 | $29 | $26 | $84 | |
| Other Non-op | $-502 | $-2.2K | $3 | $-1M | $-672.4K | $-270.1K | $8M | $-15M | |
| Pretax Income | $-56M | $-27M | $-38M | $-19M | $-9M | $-7M | $1M | $-19M | |
| Income Tax | $5.4K | $10.1K | $3.6K | $6.7K | $2.1K | $1.6K | $1.6K | $1.6K | |
| Net Income | $-56M | $-27M | $-38M | $-19M | $-9M | $-7M | $1M | $-19M | |
| EPS (Basic) | $-1.41 | $-0.73 | $-5.37 | $-8.77 | $-0.02 | $-0.03 | $0.01 | $-0.16 | |
| EPS (Diluted) | $-1.41 | $-0.73 | $-5.37 | $-8.77 | $-0.02 | $-0.03 | $-0.05 | $-0.16 | |
| Shares (Basic) | 39,662,664 | 36,486,519 | 7,006,038 | 2,221,080 | 406,599,390 | 230,746,878 | 135,154,931 | 121,154,334 | |
| Shares (Diluted) | 39,662,664 | 36,486,519 | 7,006,038 | 2,221,080 | 406,599,390 | 231,420,973 | 169,560,265 | 121,154,334 | |
| EBITDA | $-57M | $-30M | $-35M | $-18M | $-8M | $-6M | $-7M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $6M | $68M | $1M | $1M | $9M | $2M | $2M | $2M | |
| Short-term Investments | $20M | $0 | · | · | · | · | · | · | |
| Prepaid Expense | $504.9K | $202.0K | $194.3K | $780.8K | $554.2K | $190.1K | $152.7K | $93.2K | |
| Other Current Assets | $852.0K | $2M | $1M | $481.6K | $56.9K | $275 | $7.5K | $2.6K | |
| Current Assets | $27M | $71M | $12M | $9M | $10M | $3M | $2M | $2M | |
| PP&E (Net) | $898.9K | $1M | $43.3K | $87.9K | $87.7K | $7.3K | $2.0K | $3.4K | |
| PP&E (Gross) | $2M | $2M | $138.7K | · | · | · | · | · | |
| Accum. Depreciation | $773.6K | $233.5K | $95.4K | · | · | · | · | · | |
| Other Non-current Assets | $53.9K | $53.9K | $8.3K | $8.3K | $8.3K | $0 | · | · | |
| Total Assets | $28M | $73M | $12M | $9M | $10M | $3M | $2M | $2M | |
| Accounts Payable | $2M | $569.3K | $1M | $2M | $897.9K | $364.3K | $129.8K | $15.6K | |
| Accrued Liabilities | · | · | · | · | · | $5.5K | $77.9K | · | |
| Current Liabilities | $8M | $4M | $14M | $12M | $4M | $787.2K | $970.8K | $16M | |
| Capital Leases | $84.0K | $273.2K | $171.2K | $0 | $78.7K | $0 | · | · | |
| Total Liabilities | $8M | $5M | $14M | $12M | $4M | $2M | $1M | $18M | |
| Common Stock | $33.4K | $31.0K | $12.3K | $3.7K | $476.1K | $288.1K | $182.9K | $133.9K | |
| Retained Earnings | $-187M | $-131M | $-104M | $-67M | $-47M | $-39M | $-32M | $-33M | |
| Stockholders' Equity | $20M | $68M | $-2M | $-3M | $6M | $450.8K | $548.1K | $-16M | |
| Liabilities + Equity | $28M | $73M | $12M | $9M | $10M | $3M | $2M | $2M | |
| Shares Outstanding | 33,378,139 | 30,974,559 | 12,349,243 | 3,654,119 | 476,108,445 | 288,074,415 | 182,895,247 | 133,907,747 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| D&A | $723.4K | $298.6K | $124.3K | · | · | · | · | · | |
| Stock-based Comp | $8M | $8M | $987.5K | $629.0K | $869.2K | $302.7K | $680.5K | $675.0K | |
| Other Non-cash | $4M | $-7M | · | · | · | · | · | · | |
| Operating Cash Flow | $-43M | $-25M | $-14M | $-13M | $-6M | $-6M | $-6M | $-4M | |
| CapEx | $6.3K | $2M | $12.6K | $28.1K | $90.9K | $7.2K | · | $4.4K | |
| Investing Cash Flow | $-20M | $-245.6K | $7M | $5M | $-90.9K | $-7.2K | · | $-4.4K | |
| Stock Issued | · | $0 | $5M | $0 | $6M | $6M | $2M | $3M | |
| Net Stock Activity | · | $0 | $5M | $0 | $6M | $6M | $2M | · | |
| Financing Cash Flow | $29.6K | $84M | $16M | $-208.8K | $13M | $7M | $6M | $6M | |
| Net Change in Cash | $-63M | $58M | $9M | $-8M | $7M | $639.5K | $-23.4K | $2M | |
| Free Cash Flow | $-43M | $-27M | $-14M | $-13M | $-7M | $-6M | · | · | |
| Levered FCF | $-43M | $-28M | $-15M | $-13M | $-7M | $-7M | · | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| ROA | -110.7% | -62.7% | -357.6% | -205.4% | -136.1% | -281.1% | 53.2% | · | |
| ROE | -175.6% | -36.9% | 17246.1% | 619.1% | -120.6% | -569.5% | -13.3% | · | |
| ROIC | -290.5% | -44.3% | 1629.5% | 609.0% | -133.9% | -1395.5% | -1208.4% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.3 | 16.3 | 0.8 | 0.7 | 2.5 | 3.4 | 2.1 | · | |
| Quick Ratio | 3.1 | 15.8 | 0.1 | 0.1 | 2.3 | 3.1 | 1.9 | · | |
| Interest Coverage | · | -40.3 | -38.3 | -27.5 | -10.2 | -8.9 | -6.6 | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $0.60 | $2.20 | $-0.17 | $-0.00 | $0.01 | $0.00 | $0.00 | · | |
| Cash Flow / Share | $-1.09 | $-0.69 | $-1.99 | $-0.02 | $-0.02 | $-0.03 | $-0.04 | · | |
| Cash / Share | $0.18 | $2.21 | $0.10 | $0.00 | $0.02 | $0.01 | $0.01 | · | |
| EPS (TTM) | $-1.41 | $-0.73 | $-5.37 | $-8.77 | $-0.02 | $-0.03 | $-0.05 | $-0.16 |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-56M | $-27M | $-38M | $-19M | $-9M | $-7M | $1M | $-19M | |
| Market Cap | $25M | $88M | $34M | $3.65B | $6.19B | $2.88B | $5.99B | · | |
| P/E | -0.5 | -3.9 | -0.5 | -0.5 | -650.0 | -333.3 | -655.0 | -625.0 | |
| P/B | 1.3 | 1.3 | -15.8 | -1214.8 | 1055.5 | 6390.5 | 10929.2 | · | |
| P / Tangible Book | 1.3 | 1.3 | · | · | 1055.5 | 6390.5 | · | · | |
| P / Cash Flow | -0.6 | -3.5 | -2.4 | -286.7 | -955.9 | -475.8 | -993.7 | · | |
| P / FCF | -0.6 | -3.3 | -2.4 | -286.1 | -942.7 | -475.3 | · | · | |
| Earnings Yield | -188.0% | -25.8% | -197.4% | -219.2% | -0.15% | -0.30% | -0.15% | -0.16% |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | · | · | · | · | · | · | · | · | · | · | · | · | $1M | · | $2M | |
| SG&A Expense | $4M | $5M | $3M | $4M | $4M | $5M | $5M | $5M | $4M | $4M | $2M | $2M | $2M | $2M | $1M | |
| Operating Expenses | $11M | $13M | $15M | $13M | $18M | $12M | $11M | $5M | $8M | $6M | $4M | $25M | $3M | $9M | $3M | |
| Operating Income | $-11M | $-13M | $-15M | $-13M | $-18M | $-12M | $-11M | $-5M | $-8M | $-6M | $-4M | $-25M | $-3M | $-9M | $-3M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | $436.9K | $430.1K | $271.3K | $18.4K | $49.6K | $211.2K | |
| Interest Income | $103.2K | $169.6K | $313.3K | $418.5K | $533.1K | $619.1K | $732.3K | $907.7K | $961.2K | $427.6K | $50.3K | $16.6K | $24.5K | $19.0K | $0 | |
| Other Non-op | $0 | $-2.4K | $-41.1K | $0 | $0 | $40.6K | $0 | $-801 | $-359 | $-1.0K | $2M | $0 | $-2M | $-607.0K | $-205.0K | |
| Pretax Income | $-11M | $-13M | $-14M | $-13M | $-18M | $-11M | $-10M | $-4M | $-8M | $-5M | $-4M | $-25M | $-5M | $-10M | $-3M | |
| Income Tax | $3.4K | $0 | $0 | $0 | $3.4K | $2.0K | $0 | $0 | $8.1K | $2.0K | $0 | $0 | $0 | $1.6K | $0 | |
| Net Income | $-11M | $-13M | $-14M | $-13M | $-18M | $-11M | $-10M | $-4M | $-8M | $-5M | $-4M | $-25M | $-5M | $-10M | $-3M | |
| EPS (Basic) | $-0.27 | $-0.32 | $-0.37 | $-0.32 | $-0.44 | $-0.28 | $-0.25 | $-0.10 | $-0.20 | $-0.18 | $-0.03 | $-3.17 | $-1.37 | $-7.17 | $-1.58 | |
| EPS (Diluted) | $-0.27 | $-0.32 | $-0.37 | $-0.32 | $-0.44 | $-0.28 | $-0.25 | $-0.10 | $-0.20 | $-0.18 | $-0.03 | $-3.17 | $-1.37 | $-7.17 | $-1.58 | |
| Shares (Basic) | 39,694,243 | 39,681,465 | · | 39,665,927 | 39,659,266 | 39,651,888 | · | 38,819,387 | 38,669,330 | 27,999,901 | · | 7,880,546 | 3,767,578 | · | 1,983,700 | |
| Shares (Diluted) | 39,694,243 | 39,681,465 | · | 39,665,927 | 39,659,266 | 39,651,888 | · | 38,819,387 | 38,669,330 | 27,999,901 | · | 7,880,546 | 3,767,578 | · | 1,983,700 | |
| EBITDA | $-11M | $-13M | · | $-13M | $-18M | $-12M | · | $-5M | $-8M | $-6M | · | $-25M | $-3M | · | $-3M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $8M | $8M | $6M | $18M | $24M | $46M | $68M | $67M | $74M | $83M | $1M | $5M | $3M | $1M | $415.4K | |
| Short-term Investments | $2M | $9M | $20M | $17M | $25M | $13M | $0 | · | · | · | · | · | · | · | · | |
| Receivables | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Prepaid Expense | $415.2K | $1M | $504.9K | $4M | $1M | $575.4K | $202.0K | $664.6K | $1M | $640.5K | $194.3K | $207.2K | $957.6K | $780.8K | $708.5K | |
| Other Current Assets | $479.6K | $234.8K | $852.0K | $900.2K | $733.4K | $3M | $2M | $3M | $3M | $2M | $1M | $867.9K | $820.0K | $481.6K | $143.9K | |
| Current Assets | $11M | $19M | $27M | $40M | $51M | $63M | $71M | $80M | $87M | $95M | $12M | $15M | $4M | $9M | $3M | |
| PP&E (Net) | $32.9K | $756.1K | $898.9K | $1M | $1M | $1M | $1M | $2M | $45.8K | $36.1K | $43.3K | $55.3K | $77.1K | $87.9K | $86.2K | |
| PP&E (Gross) | $140.8K | · | $2M | · | · | · | $2M | $2M | · | · | $138.7K | · | · | · | · | |
| Accum. Depreciation | $107.9K | · | $773.6K | · | · | · | $233.5K | $99.6K | · | · | $95.4K | · | · | · | · | |
| Other Non-current Assets | $8.3K | $35.9K | $53.9K | $53.9K | $53.9K | $53.9K | $53.9K | $26.3K | $8.3K | $8.3K | $8.3K | $8.3K | $8.3K | $8.3K | $8.3K | |
| Total Assets | $11M | $19M | $28M | $41M | $52M | $65M | $73M | $82M | $87M | $95M | $12M | $16M | $5M | $9M | $3M | |
| Accounts Payable | $4M | $4M | $2M | $3M | $3M | $2M | $569.3K | $780.0K | $1M | $1M | · | $2M | $1M | · | $2M | |
| Current Liabilities | $12M | $10M | $8M | $8M | $8M | $5M | $4M | $6M | $14M | $16M | $14M | $14M | $9M | $12M | $6M | |
| Capital Leases | $0 | $0 | $84.0K | $120.2K | $172.5K | $223.5K | $273.2K | $108.1K | $129.9K | $151.0K | $171.2K | $190.5K | $0 | $0 | $8.2K | |
| Total Liabilities | $12M | $10M | $8M | $8M | $8M | $6M | $5M | $6M | $14M | $16M | $14M | $14M | $9M | $12M | $6M | |
| Common Stock | $35.1K | $35.1K | $33.4K | $31.0K | $31.0K | $31.0K | $31.0K | $30.3K | $28.1K | $28.1K | $12.3K | $12.3K | $971.5K | $3.7K | $495.9K | |
| Retained Earnings | $-210M | $-199M | $-187M | $-172M | $-160M | $-142M | $-131M | $-121M | $-117M | $-109M | $-104M | $-100M | $-72M | $-67M | $-57M | |
| AOCI | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Stockholders' Equity | $-497.3K | $9M | $20M | $33M | $44M | $59M | $68M | $76M | $73M | $79M | $-2M | $2M | $-5M | $-3M | $-3M | |
| Liabilities + Equity | $11M | $19M | $28M | $41M | $52M | $65M | $73M | $82M | $87M | $95M | $12M | $16M | $5M | $9M | $3M | |
| Shares Outstanding | 35,143,722 | 35,126,884 | 33,378,139 | 30,989,046 | 30,988,108 | 30,974,559 | 30,974,559 | 30,338,290 | 28,067,907 | 28,062,907 | 12,349,243 | 12,338,910 | 971,549,608 | 3,654,119 | 495,925,112 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $157.6K | $172.9K | $180.0K | $178.9K | $187.1K | $177.4K | $175.3K | $47.5K | $29.8K | $27.6K | $86.1K | $12.8K | · | · | · | |
| Stock-based Comp | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $592.9K | $160.2K | $131.6K | $203.2K | $144.1K | |
| Other Non-cash | · | $2M | · | · | · | $-461.4K | · | · | · | · | · | · | · | · | · | |
| Operating Cash Flow | $-7M | $-9M | $-10M | $-13M | $-11M | $-9M | $-8M | $-5M | $-7M | $-5M | $-4M | $-4M | $-4M | $-5M | $-2M | |
| CapEx | $0 | $0 | $0 | $0 | $0 | $6.3K | $50.0K | $2M | $32.5K | $3.2K | $7.0K | $3.7K | $1.9K | $12.5K | $10.3K | |
| Investing Cash Flow | $7M | $11M | $-3M | $8M | $-12M | $-13M | $90.4K | $-1M | $-32.5K | $1M | $-7.0K | $1M | $6M | $6M | $-366.1K | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | $-7M | · | · | · | · | |
| Financing Cash Flow | $-101.0K | $-71.5K | $11.4K | $0 | $18.2K | $0 | $5.6K | $0 | $-2M | $86M | $-22.7K | $17M | $-45.3K | $34.2K | $-91.8K | |
| Net Change in Cash | $-80.7K | $2M | $-13M | $-5M | $-23M | $-22M | $-8M | $-7M | $-9M | $82M | $-4M | $14M | $1M | $829.1K | $-3M | |
| Taxes Paid | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Free Cash Flow | · | $-9M | · | · | · | $-9M | · | · | · | $-5M | · | · | $-4M | · | · | |
| Levered FCF | · | · | · | · | · | · | · | · | · | $-5M | · | · | · | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -34.1% | -29.7% | · | -20.8% | -25.3% | -13.9% | · | -8.0% | -17.1% | -10.1% | · | -270.1% | -87.6% | · | -43.0% | |
| ROE | -50.0% | -36.6% | · | -23.5% | -30.3% | -16.1% | · | -10.1% | -21.8% | -13.6% | · | 3138.4% | 571.8% | · | -125.6% | |
| ROIC | 2224.9% | -140.6% | · | -40.4% | -41.8% | -19.9% | · | -6.6% | -11.6% | -7.8% | · | -1457.3% | · | · | 89.0% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.0 | 1.8 | · | 4.8 | 6.1 | 11.8 | · | 14.2 | 6.1 | 6.0 | · | 1.1 | 0.5 | · | 0.4 | |
| Quick Ratio | 0.9 | 1.6 | · | 4.2 | 5.8 | 11.1 | · | 12.0 | 5.2 | 5.3 | · | 0.4 | 0.3 | · | 0.1 | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -14.1 | · | -91.1 | -168.5 | · | -13.8 |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $-0.01 | $0.26 | · | $1.06 | $1.41 | $1.91 | · | $2.50 | $2.59 | $2.81 | · | $0.14 | $-0.00 | · | $-0.01 | |
| Cash Flow / Share | · | $-0.22 | · | · | · | $-0.23 | · | · | · | $-0.17 | · | · | $-0.00 | · | · | |
| Cash / Share | $0.23 | $0.23 | · | $0.60 | $0.77 | $1.50 | · | $2.22 | $2.64 | $2.97 | · | $0.42 | $0.00 | · | $0.00 | |
| EPS (TTM) | $-1.28 | $-1.45 | · | $-1.29 | $-1.07 | $-0.83 | · | $-0.51 | $-3.58 | $-4.18 | · | $-12.51 | $-10.13 | · | $-1.60 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-50M | $-57M | · | $-51M | $-42M | $-33M | · | $-21M | $-42M | $-37M | · | $-43M | $-22M | · | $-12M | |
| Market Cap | $24M | $22M | · | $122M | $130M | $49M | · | $119M | $225M | $439M | · | $50M | $4.13B | · | $3.22B | |
| P/E | -0.5 | -0.4 | · | -3.0 | -3.9 | -1.9 | · | -7.7 | -2.2 | -3.7 | · | -0.3 | -0.4 | · | -4.1 | |
| P/B | -49.0 | 2.4 | · | 3.7 | 3.0 | 0.8 | · | 1.6 | 3.1 | 5.6 | · | 29.8 | -863.7 | · | -981.3 | |
| P / Tangible Book | · | 2.4 | · | 3.7 | 3.0 | 0.8 | · | 1.6 | 3.1 | 5.6 | · | 29.8 | · | · | · | |
| P / Cash Flow | · | -2.5 | · | · | · | -5.4 | · | · | · | -93.2 | · | · | -1016.8 | · | · | |
| Earnings Yield | -184.7% | -235.8% | · | -32.8% | -25.6% | -52.2% | · | -13.0% | -44.7% | -26.7% | · | -305.9% | -238.4% | · | -24.6% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Net Income | $-56M | $-27M | $-38M | $-19M | $-9M |
| Diluted EPS | $-1.41 | $-0.73 | $-5.37 | $-8.77 | $-0.02 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 3.3 | 16.3 | 0.8 | 0.7 | 2.5 |
| Quick Ratio | 3.1 | 15.8 | 0.1 | 0.1 | 2.3 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | $-43M | $-27M | $-14M | $-13M | $-7M |
Institutional owners (13F) 46 filers · $11.9M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
46
Value held
$11.9M
New positions
6
Exited positions
3
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 6 (+1 vs prior Q) | 3 (-11 vs prior Q) | 3 (-7 vs prior Q) | 13 (+4 vs prior Q) | -82K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| 5AM Venture Management, LLC | $6,712,366 | 9,681,763 | 56.47% | Shares |
| Versant Venture Management, LLC | $1,391,941 | 2,007,704 | 11.71% | Shares |
| BAKER BROS. ADVISORS LP | $1,092,116 | 1,575,243 | 9.19% | Shares |
| VANGUARD GROUP INC | $662,089 | 882,785 | 5.57% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $529,370 | 763,882 | 4.45% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $470,701 | 678,928 | 3.96% | Shares |
| PLATINUM INVESTMENT MANAGEMENT LTD | $161,605 | 233,095 | 1.36% | Shares |
| BlackRock, Inc. | $161,452 | 232,874 | 1.36% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $151,232 | 218,055 | 1.27% | Shares |
| MILLENNIUM MANAGEMENT LLC | $137,637 | 198,524 | 1.16% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $72,231 | 104,229 | 0.61% | Shares |
| CITADEL ADVISORS LLC | $61,426 | 88,600 | 0.52% | Call option |
| STATE STREET CORP | $51,186 | 73,830 | 0.43% | Shares |
| UBS Group AG | $51,143 | 73,800 | 0.43% | Shares |
| NORTHERN TRUST CORP | $39,052 | 56,327 | 0.33% | Shares |
| TWO SIGMA ADVISERS, LP | $30,724 | 40,982 | 0.26% | Shares |
| Qube Research & Technologies Ltd | $29,869 | 43,082 | 0.25% | Shares |
| CITADEL ADVISORS LLC | $24,543 | 35,400 | 0.21% | Put option |
| SIMPLEX TRADING, LLC | $18,702 | 26,976 | 0.16% | Shares |
| XTX Topco Ltd | $14,554 | 20,993 | 0.12% | Shares |
| Engineers Gate Manager LP | $14,001 | 20,194 | 0.12% | Shares |
| GROUP ONE TRADING LLC | $3,182 | 4,589 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $3,158 | 4,557 | 0.03% | Shares |
| MORGAN STANLEY | $1,711 | 2,469 | 0.01% | Shares |
| BARCLAYS PLC | $455 | 655 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $413 | 600 | 0.00% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $275 | 400 | 0.00% | Shares |
| JPMORGAN CHASE & CO | $44 | 66 | 0.00% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $36 | 52 | 0.00% | Shares |
| TD Waterhouse Canada Inc. | $35 | 52 | 0.00% | Shares |
| Federation des caisses Desjardins du Quebec | $35 | 51 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $27 | 39 | 0.00% | Shares |
| Optiver Holding B.V. | $14 | 20 | 0.00% | Shares |
| CoreCap Advisors, LLC | $6 | 8 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $5 | 8 | 0.00% | Shares |
| GILPIN WEALTH MANAGEMENT, LLC | $3 | 4 | 0.00% | Shares |
| Plante Moran Financial Advisors, LLC | $2 | 3 | 0.00% | Shares |
| PFS Partners, LLC | $1 | 1 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $1 | 1 | 0.00% | Shares |
| Leo H. Evart, Inc. | $1 | 1 | 0.00% | Shares |
| WELLS FARGO & COMPANY/MN | $1 | 1 | 0.00% | Shares |
| NFSG Corp | $1 | 1 | 0.00% | Shares |
| MCGUIRE CAPITAL ADVISORS INC | $1 | 2 | 0.00% | Shares |
| FMR LLC | $1 | 1 | 0.00% | Shares |
| IFP Advisors, Inc | $1 | 1 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $0 | 120 | 0.00% | Shares |
Activists & 5%+ owners 8 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| 5AM Co-Investors II, L.P., 5AM Partners II, LLC, 5AM Partners VII, LLC, 5AM Ventures II, L.P., 5AM Ventures VII, L.P., Andrew J. Schwab, John D. Diekman, Kush Parmar, Scott M. Rocklage ×2 filings | Sept. 24, 2026 | 26.10% | Amendment | · | SEC |
| 5AM Partners VII, LLC, 5AM Ventures VII, L.P., 5AM Partners II, LLC, 5AM Ventures II, L.P., 5AM Co-Investors II, L.P., Andrew J. Schwab, Kush Parmar, John D. Diekman, Scott M. Rocklage ×2 filings | Dec. 16, 2025 | 34.00% | Amendment | · | SEC |
| 5AM Ventures VII, L.P., 5AM Partners VII, LLC, 5AM Ventures II, L.P., 5AM Co-Investors II, L.P., 5AM Partners II, LLC, Andrew J. Schwab, Kush Parmar, John D. Diekman, Scott M. Rocklage ×3 filings | March 13, 2024 | · | Initial filing | · | SEC |
| Emerald Health Sciences Inc. ×9 filings | March 20, 2023 | · | Initial filing | · | SEC |
| Undisclosed reporting person | March 28, 2017 | · | Initial filing | · | SEC |
| Cosmas N. Lykos ×2 filings | Feb. 1, 2016 | · | Initial filing | · | SEC |
| YOSBANI MENDEZ ×2 filings | Nov. 12, 2014 | · | Initial filing | Passive investment | SEC |
| Reg Alexander Lapham | Nov. 10, 2014 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 31 insiders · 13 officers · 18 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Punit Dhillon | Chief Executive Officer | Aug. 7, 2026 A | 1,419,823 | 0 | 0 | $0 |
| Brian Stuart Murphy | CEO, Chief Medical Officer | Jan. 18, 2018 A | 1,275,000 | 0 | 0 | $0 |
| John B Hollister | Chief Executive Officer | Dec. 4, 2014 A | · | 0 | 0 | $0 |
| Kaitlyn Melanie Arsenault | Chief Financial Officer | Feb. 6, 2026 A | 167,522 | 0 | 0 | $0 |
| Elena Traistaru | CFO and Secretary | Aug. 7, 2020 A | · | 0 | 0 | $0 |
| Douglas A Cesario | CFO and Secretary | July 23, 2018 A | 643,501 | 0 | 0 | $0 |
| Elizabeth Berecz | Chief Financial Officer | Jan. 18, 2018 A | 1,050,000 | 0 | 0 | $0 |
| Tuan Tu Diep | Chief Operating Officer | March 31, 2026 D | 82,259 | 0 | 0 | $0 |
| Christopher Twitty | Chief Scientific Officer | March 31, 2026 D | · | 0 | 0 | $0 |
| Puneet S. Arora | Chief Medical Officer | Feb. 6, 2026 A | · | 0 | 0 | $0 |
| Dennis D Kim | Chief Medical Officer | Aug. 7, 2020 A | · | 0 | 0 | $0 |
| Cosmas N Lykos | Chairman | Jan. 18, 2018 A | 4,599,400 | 0 | 0 | $0 |
| Douglas S Ingram | Vice Chairman | Oct. 20, 2015 A | 372,500 | 0 | 0 | $0 |
| Andrew J. Schwab | Director | Sept. 23, 2026 S | 0 | 0 | 15 | $-444,600 |
| Deborah H. Charych | Director | March 31, 2026 A | · | 0 | 0 | $0 |
| Paul A. Grayson | Director | March 31, 2026 A | 259,701 | 0 | 0 | $0 |
| Karen L. Smith | Director | March 31, 2026 A | · | 0 | 0 | $0 |
| Annalisa Jenkins | Director | March 31, 2026 A | · | 0 | 0 | $0 |
| Keith Wayne Ward | Director | Feb. 29, 2024 A | · | 0 | 0 | $0 |
| Praveen Tyle | Director | Feb. 29, 2024 A | · | 0 | 0 | $0 |
| Margaret Dalesandro | Director | Feb. 29, 2024 A | · | 0 | 0 | $0 |
| Sukhwinder Singh Rai | Director | Jan. 5, 2023 A | 73,561 | 0 | 0 | $0 |
| James L Heppell | Director | Sept. 14, 2021 A | 500,000 | 0 | 0 | $0 |
| Avtar S Dhillon | Director | Oct. 10, 2018 A | · | 0 | 0 | $0 |
| Gerald W. Mclaughlin | Director | Oct. 20, 2015 A | 61,250 | 0 | 0 | $0 |
| Thomas George | Director | Oct. 20, 2015 A | 60,000 | 0 | 0 | $0 |
| Emerald Health Sciences Inc. | 10% owner | Feb. 22, 2023 D | 169,407,901 | 0 | 0 | $0 |
| Reg Alexander Lapham | 10% owner | March 13, 2017 X | 3,787,500 | 0 | 0 | $0 |
| Brian D Ladin | 10% owner | April 10, 2015 S | 249,098 | 0 | 0 | $0 |
| Francisco Javier Mendez | · | Oct. 31, 2014 J | 0 | 0 | 0 | $0 |
| Yosbani Mendez | · | Oct. 31, 2014 J | 2,440 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 2 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
SKYE Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 12 analysts
BUY
Median target
$48.00
+2757.1%
2 16.7%
Strong Buy
7 58.3%
Buy
3 25.0%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
4 analysts · 2026-09-30Mean target $68.00 +3947.6%
← Below all targets
Current price $1.68
Low$16.00
Mean$68.00
High$160.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| SKYE | $25M | -0.5 | · | · | -175.6% | · |
| SNGX | $14M | -0.6 | -85.8% | · | -311.2% | · |
| ENSC | $4M | -0.2 | -2.8% | -200.9% | -294.0% | · |
| KALA | $15M | -0.2 | · | · | -1423.8% | · |
| IMNN | $13M | -0.6 | · | · | -298.2% | · |
| BIAF | · | · | · | · | · | · |
| ACXP | $6M | -0.5 | · | · | -180.3% | · |
| BOLT | $11M | -0.3 | 0.07% | -433.7% | -102.2% | · |
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Source: SEC 10-Q filed Aug 14, 2026