Insider at

04

Insider transactions

05
0 buys (P) 50 sells (S) Net: $-34,272,769 + 25 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

25 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Sept. 4, 2026 KRYS S 520 $354.54 $184,361 1,372,023 Direct -0.04% Disposed -9.1% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 2,029 $355.57 $721,452 1,369,994 Direct -0.15% Disposed -9.4% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,297 $356.37 $1,174,952 1,366,697 Direct -0.24% Disposed -9.6% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,981 $357.57 $1,423,486 1,362,716 Direct -0.29% Disposed -9.9% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,143 $358.42 $1,126,514 1,359,573 Direct -0.23% Disposed -10.1% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,357 $359.39 $1,206,472 1,356,216 Direct -0.25% Disposed -10.3% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 2,266 $360.46 $816,802 1,353,950 Direct -0.17% Disposed -10.6% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 1,214 $361.61 $438,995 1,352,736 Direct -0.09% Disposed -10.9% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 2,010 $362.65 $728,926 1,350,726 Direct -0.15% Disposed -11.1% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 573 $363.34 $208,194 1,350,153 Direct -0.04% Disposed -11.3% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 1,358 $364.48 $494,964 1,348,795 Direct -0.10% Disposed -11.6% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 847 $365.42 $309,511 1,347,948 Direct -0.06% Disposed -11.8% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 405 $366.56 $148,457 1,347,543 Direct -0.03% Disposed -12.1% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 40 $312.23 $12,489 1,450,253 Direct 0.00% Disposed 3.2% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 964 $311.36 $300,151 1,450,293 Direct -0.07% Disposed 3.5% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 2,652 $310.43 $823,260 1,451,257 Direct -0.18% Disposed 3.8% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 2,784 $309.49 $861,620 1,453,909 Direct -0.19% Disposed 4.1% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 4,830 $308.47 $1,489,910 1,456,693 Direct -0.33% Disposed 4.5% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 11,461 $307.68 $3,526,320 1,461,523 Direct -0.78% Disposed 4.7% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 589 $306.33 $180,428 1,472,984 Direct -0.04% Disposed 5.2% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 544 $304.81 $165,817 1,473,573 Direct -0.04% Disposed 5.7% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 176 $303.17 $53,358 1,474,117 Direct -0.01% Disposed 6.3% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 640 $302.24 $193,434 1,474,293 Direct -0.04% Disposed 6.6% (price as of 2026-10-02)
June 4, 2026 KRYS S 320 $300.75 $96,240 1,474,933 Direct -0.02% Disposed 7.2% (price as of 2026-10-02)
March 4, 2026 KRYS S 483 $257.31 $124,281 1,499,770 Direct -0.03% Disposed 25.2% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 470 $258.38 $121,439 1,499,300 Direct -0.03% Disposed 24.7% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 1,377 $259.87 $357,841 1,497,923 Direct -0.09% Disposed 24.0% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 3,128 $260.49 $814,813 1,494,795 Direct -0.21% Disposed 23.7% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 2,962 $261.41 $774,296 1,491,833 Direct -0.20% Disposed 23.3% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 2,380 $262.44 $624,607 1,489,453 Direct -0.16% Disposed 22.8% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 2,043 $263.70 $538,739 1,487,410 Direct -0.14% Disposed 22.2% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 8,798 $264.85 $2,330,150 1,478,612 Direct -0.59% Disposed 21.7% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 2,439 $265.59 $647,774 1,476,173 Direct -0.16% Disposed 21.3% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 920 $266.56 $245,235 1,475,253 Direct -0.06% Disposed 20.9% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 956 $214.28 $204,852 1,507,100 Direct -0.06% Disposed 50.4% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 344 $215.48 $74,125 1,506,756 Direct -0.02% Disposed 49.6% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 1,600 $217.04 $347,264 1,505,156 Direct -0.11% Disposed 48.5% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 2,577 $218.72 $563,641 1,502,579 Direct -0.17% Disposed 47.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 5,693 $219.55 $1,249,898 1,496,886 Direct -0.38% Disposed 46.8% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 2,625 $220.34 $578,392 1,494,261 Direct -0.18% Disposed 46.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 10,505 $221.78 $2,329,799 1,483,756 Direct -0.70% Disposed 45.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 700 $222.20 $155,540 1,483,056 Direct -0.05% Disposed 45.0% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 700 $214.25 $149,975 1,438,011 Indirect -0.05% Disposed 50.4% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 600 $215.49 $129,294 1,437,411 Indirect -0.04% Disposed 49.6% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 1,400 $216.97 $303,758 1,436,011 Indirect -0.10% Disposed 48.5% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 3,593 $218.83 $786,256 1,432,418 Indirect -0.25% Disposed 47.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 5,419 $219.68 $1,190,446 1,426,999 Indirect -0.38% Disposed 46.7% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 2,627 $220.52 $579,306 1,424,372 Indirect -0.18% Disposed 46.1% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 10,461 $221.82 $2,320,459 1,413,911 Indirect -0.73% Disposed 45.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 200 $222.38 $44,476 1,413,711 Indirect -0.01% Disposed 44.9% (price as of 2026-10-02)
July 16, 2025 KRYS S 10b5-1 1,389 $150.00 $208,350 1,508,056 Direct -0.09% Disposed 114.9% (price as of 2026-10-02)
July 16, 2025 KRYS S 10b5-1 1,529 $150.00 $229,350 1,438,711 Indirect -0.11% Disposed 114.9% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 2,184 $150.68 $329,085 1,510,345 Direct -0.14% Disposed 113.9% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 900 $151.79 $136,611 1,509,445 Direct -0.06% Disposed 112.3% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 2,236 $150.68 $336,920 1,441,040 Indirect -0.15% Disposed 113.9% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 800 $151.79 $121,432 1,440,240 Indirect -0.06% Disposed 112.3% (price as of 2026-10-02)
July 14, 2025 KRYS S 10b5-1 13,400 $150.30 $2,014,020 1,512,529 Direct -0.88% Disposed 114.4% (price as of 2026-10-02)
July 14, 2025 KRYS S 10b5-1 13,335 $150.29 $2,004,117 1,443,376 Indirect -0.92% Disposed 114.4% (price as of 2026-10-02)
July 14, 2025 KRYS S 10b5-1 100 $151.00 $15,100 1,443,276 Indirect -0.01% Disposed 113.4% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 6,627 $150.22 $995,508 1,526,229 Direct -0.43% Disposed 114.5% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 300 $151.39 $45,417 1,525,929 Direct -0.02% Disposed 112.9% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 6,500 $150.23 $976,495 1,457,011 Indirect -0.44% Disposed 114.5% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 300 $151.39 $45,417 1,456,711 Indirect -0.02% Disposed 112.9% (price as of 2026-10-02)
July 9, 2025 KRYS S 10b5-1 200 $150.07 $30,014 1,532,856 Direct -0.01% Disposed 114.8% (price as of 2026-10-02)
July 9, 2025 KRYS S 10b5-1 200 $150.14 $30,028 1,463,511 Indirect -0.01% Disposed 114.7% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,100 $175.83 $193,413 1,556,956 Direct -0.07% Disposed 83.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 4,944 $176.80 $874,099 1,552,012 Direct -0.32% Disposed 82.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 10,931 $177.62 $1,941,564 1,541,081 Direct -0.70% Disposed 81.4% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 6,769 $178.77 $1,210,094 1,534,312 Direct -0.44% Disposed 80.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,256 $179.57 $225,540 1,533,056 Direct -0.08% Disposed 79.5% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,639 $175.97 $288,415 1,487,072 Indirect -0.11% Disposed 83.1% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 4,579 $176.88 $809,934 1,482,493 Indirect -0.31% Disposed 82.2% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 10,937 $177.66 $1,943,067 1,471,556 Indirect -0.74% Disposed 81.4% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 6,514 $178.76 $1,164,443 1,465,042 Indirect -0.44% Disposed 80.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,331 $179.55 $238,981 1,463,711 Indirect -0.09% Disposed 79.5% (price as of 2026-10-02)

Showing latest 100 of 284 transactions

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
Feb. 27, 2026 KRYS Restricted Stock Units Common Stock (8,750) · · 8,750 Disposed
Feb. 27, 2026 KRYS Performance Stock Units Common Stock (26,250) · · 26,250 Disposed
Feb. 27, 2026 KRYS Restricted Stock Units Common Stock (5,725) · · 5,725 Disposed
Feb. 27, 2026 KRYS Stock Option (Right to Buy) Common Stock (45,249) $275.64 Feb. 26, 2036 45,249 Acquired
Feb. 27, 2026 KRYS Restricted Stock Units Common Stock (18,140) · · 18,140 Acquired
Feb. 28, 2025 KRYS Performance Stock Units Common Stock (12,500) · · 12,500 Disposed
Feb. 28, 2025 KRYS Restricted Stock Units Common Stock (8,750) · · 8,750 Disposed
Feb. 28, 2025 KRYS Performance Stock Units Common Stock (26,250) · · 26,250 Disposed
Feb. 28, 2025 KRYS Stock Option (Right to Buy) Common Stock (39,300) $179.25 Feb. 28, 2035 39,300 Acquired
Feb. 28, 2025 KRYS Restricted Stock Units Common Stock (22,900) · · 22,900 Acquired
Feb. 29, 2024 KRYS Restricted Stock Units Common Stock (35,000) · · 35,000 Acquired
Feb. 29, 2024 KRYS Performance Stock Units Common Stock (52,500) · · 52,500 Acquired
Feb. 28, 2024 KRYS Performance Stock Units Common Stock (12,500) · · 12,500 Disposed
Feb. 28, 2023 KRYS Stock Option (Right to Buy) Common Stock (50,000) $81.91 Feb. 28, 2033 50,000 Acquired
Feb. 28, 2023 KRYS Performance Stock Units Common Stock · · 25,000 Acquired
Feb. 28, 2022 KRYS Stock Option (Right to Buy) Common Stock (50,000) $63.55 Feb. 28, 2032 50,000 Acquired
Feb. 26, 2021 KRYS Stock Option (Right to Buy) Common Stock (61,200) $78.89 Feb. 26, 2025 61,200 Acquired
Sept. 22, 2017 KRYS Series A Convertible Preferred Stock Common Stock (112,162) · · 112,162 Disposed
Jan. 29, 2016 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (14,657) $6.88 Jan. 3, 2022 14,657 Disposed
Jan. 28, 2016 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (14,657) $6.88 Dec. 5, 2021 14,657 Disposed
May 18, 2015 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (42,000) $7.12 Dec. 5, 2021 42,000 Disposed
May 18, 2015 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (42,000) $7.12 Jan. 3, 2022 42,000 Disposed
March 20, 2014 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (500,000) $30.72 March 20, 2024 500,000 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 5 holdings

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Sept. 25, 2017 KRYS Series A Convertible Preferred Stock [F1]→ Common Stock · Indirect
Sept. 19, 2017 KRYS Common Stock 1,835,249 Direct
Sept. 19, 2017 KRYS Common Stock 1,835,249 Indirect
Sept. 19, 2017 KRYS Series A Convertible Preferred Stock [F2] 112,162 Indirect
Aug. 7, 2013 PGEN Option to Purchase Common Stock→ Common Stock (571,428) 571,428 Direct