PGEN Precigen, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$7.01
Price · Aug 19, 2026
Fundamentals as of Aug 4, 2026
52W Range
$3–$7
93% of range
Analyst Rating
BUY
9 analysts
Price Target
$14
+107% upside
P/E (TTM)
-5.1
ROE
3159.1%
Net Profit Margin
-2588.2%

About Precigen, Inc. - Common Stock Company overview from Wikipedia

Precigen, Inc. is an American biotechnology company. Its president and CEO is Helen Sabzevari.

Read more

Precigen, Inc. (formerly Intrexon Corporation, NASDAQ: PGEN) is an American biotechnology company. Its president and CEO is Helen Sabzevari.

Intrexon was founded in 1998, and is headquartered in Germantown, Maryland. With a suite of proprietary and complementary technologies, Intrexon applies engineering to biological systems to enable DNA-based control over the function and output of living cells.

## History

In 2015, Intrexon purchased Oxitec, a maker of genetically sterile insects, for $160 million. In April 2019, Intrexon formed a subsidiary called Precigen, with a focus on human gene therapy. Precigen went on to win orphan drug status from the FDA for a CAR-T based therapy (investigational drug name PRGN-3006) to treat acute myeloid leukemia. In early 2020, Intrexon adopted the name of its subsidiary, Precigen, and narrowed its focus to human gene editing. With the change in name the CEO of subsidiary Precigen, Helen Sabzevari, took over leadership of the company from Randal J. Kirk.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

PGEN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$7.01
Market Cap
$2.49B
P/E (TTM)
-5.1
EPS (TTM)
$-1.37
Revenue (TTM)
$10M
Div Yield
—
ROE
3159.1%
Debt/Equity
4.5
52W Range
$3 – $7

PGEN Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $10M
10-point trend, -94.9%
2016-12-31 → 2025-12-31
EPS $-1.37
7-point trend, +34.4%
2019-12-31 → 2025-12-31
Free Cash Flow $-90M
8-point trend, -2.5%
2016-12-31 → 2025-12-31
Margins -2588.2%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
PGEN
Peer Median
P/E (TTM)
5-point trend, +61.3%
-5.1
55.4
P/S (TTM)
5-point trend, +1448.9%
257.6
7.7
P/B
5-point trend, +467.0%
119.3
7.1
EV / EBITDA
5-point trend, -133.0%
-23.2
—
Price / FCF
5-point trend, -219.9%
-27.8
—

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
PGEN
Peer Median
Operating Margin
3-point trend, -1640.6%
-1141.1%
—
Net Profit Margin
5-point trend, -5009.0%
-2588.2%
-2.0%
ROA
5-point trend, -203.0%
-166.7%
-32.7%
ROE
5-point trend, +2229.6%
3159.1%
-37.9%
ROIC
4-point trend, -348.6%
-96.9%
—

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
PGEN
Peer Median
Debt / Equity
5-point trend, +46.6%
4.5
18.7
Current Ratio
5-point trend, +61.8%
3.1
7.4
Quick Ratio
5-point trend, +250.4%
2.7
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
PGEN
Peer Median
Revenue YoY
5-point trend, -32.1%
146.7%
—
Revenue CAGR 3Y
5-point trend, -32.1%
-28.9%
—
Revenue CAGR 5Y
5-point trend, -32.1%
-21.3%
—

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
PGEN
Peer Median
EPS (Diluted)
5-point trend, -191.5%
$-1.37
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
PGEN
Peer Median

PGEN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 9 analysts
  • Strong Buy 2 22.2%
  • Buy 5 55.6%
  • Hold 2 22.2%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

2 analysts · 2026-08-13
Median target $14.50 +106.8%
Mean target $14.50 +106.8%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.12%
Period EPS Actual EPS Est Surprise
June 30, 2026 $0.05 $-0.01 0.06%
March 31, 2026 $-0.02 $-0.03 0.01%
Dec. 31, 2025 $-0.07 $-0.09 0.01%
Sept. 30, 2025 $-1.06 $-0.10 -0.96%
June 30, 2025 $-0.09 $-0.08 -0.01%
March 31, 2025 $-0.07 $-0.08 0.01%
Dec. 31, 2024 $-0.06 $-0.06 -0.00%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PGEN $1.48B -3.1 146.7% -2588.2% 3159.1% —
RARE $2.22B -3.9 20.2% -85.4% -1613.2% —
BCRX $1.66B 6.4 94.1% 30.2% -97.6% —
COAG — — — — — —
KLRA — — — — — —
CDNA $959M -47.1 13.8% -5.6% -6.8% —
VERA — -10.9 — — -55.9% —
MLYS $2.96B -15.8 — — -32.2% —
VCEL $1.82B 112.5 16.4% 6.0% 5.0% 74.4%
PVLA $1.30B -28.2 65.3% -1610.6% -110.1% —
BHVN $1.50B -1.6 — — -310.8% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, -86.5% $10M $4M $6M $27M $14M $32M $91M $151M $231M $191M $174M $72M
Cost of Revenue 4-point trend, +201.4% · · · · · · · · $33M $38M $41M $11M
R&D Expense 8-point trend, -29.9% $41M $53M $49M · · · · $405M $143M $112M $147M $59M
SG&A Expense 8-point trend, +10.2% $70M $41M $40M · · · · $138M $146M $142M $109M $64M
Operating Expenses 8-point trend, -15.3% $120M $139M $106M · · · · $666M $369M $316M $320M $142M
Operating Income 8-point trend, -58.0% $-111M $-135M $-100M · · · · $-506M $-138M $-125M $-147M $-70M
Interest Expense 5-point trend, +1180.8% · · · · · · · $9M $611.0K $861.0K $1M $666.0K
Other Non-op 8-point trend, +125.6% $43.0K $6M $627.0K · · · · $630.0K $1M $2M $1M $-168.0K
Pretax Income 12-point trend, -192.4% $-251M $-128M $-96M $-80M $-111M $-105M $-171M $-396M $-78M $-194M $-87M $-86M
Income Tax 12-point trend, +102.9% $3.0K $-2M $-458.0K $-189.0K $-160.0K $-82.0K $-930.0K $-15M $2M $-4M $1M $-103.0K
Net Income 12-point trend, -206.3% $-251M $-126M $-96M $28M $-92M $-171M $-322M $-509M $-117M $-187M $-84M $-82M
EPS (Basic) 7-point trend, +34.4% $-1.37 $-0.47 $-0.39 $0.14 $-0.47 $-1.02 $-2.09 · · · · ·
EPS (Diluted) 7-point trend, +34.4% $-1.37 $-0.47 $-0.39 $0.14 $-0.47 $-1.02 $-2.09 · · · · ·
Shares (Basic) 7-point trend, +103.1% 312,980,562 267,727,426 244,536,221 200,360,821 197,759,900 167,065,539 154,138,774 · · · · ·
Shares (Diluted) 7-point trend, +103.1% 312,980,562 267,727,426 244,536,221 200,360,821 197,759,900 167,065,539 154,138,774 · · · · ·
EBITDA 9-point trend, -80.2% $-107M · · $11M $14M $18M $25M $-472M $-107M $-101M · $-60M
Balance Sheet 27
Annual Balance Sheet data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +10.1% $30M $30M $8M $5M $36M $52M $66M $97M $68M $63M $136M $27M
Short-term Investments 12-point trend, -23.6% $68M $68M $55M $51M $72M $48M $9M $120M $6M $175M $103M $88M
Receivables 12-point trend, -73.1% $4M $926.0K $902.0K $978.0K $1M $16M $21M $21M $20M $22M $25M $15M
Prepaid Expense 12-point trend, -8.6% $3M $3M $4M $5M $5M $7M $6M $5M $7M $7M $7M $4M
Current Assets 12-point trend, -34.1% $115M $102M $69M $118M $157M $149M $235M $285M $154M $315M $324M $175M
PP&E (Net) 12-point trend, -63.8% $14M $14M $7M $7M $9M $35M $44M $87M $113M $65M $43M $38M
PP&E (Gross) 12-point trend, -37.9% $38M $37M $31M $31M $30M $70M $80M $136M $158M $99M $69M $60M
Accum. Depreciation 12-point trend, +5.9% $24M $23M $24M $23M $21M $35M $36M $49M $46M $34M $26M $22M
Goodwill 12-point trend, -84.9% $15M $19M $27M $37M $38M $54M $54M $94M $94M $157M $165M $101M
Intangibles 12-point trend, -95.2% $3M $4M $41M $44M $52M $65M $68M $89M $233M $226M $248M $66M
Other Non-current Assets 12-point trend, -28.6% $908.0K $371.0K $767.0K $1M $936.0K $2M $1M $2M $4M $4M $4M $1M
Total Assets 12-point trend, -73.0% $156M $145M $151M $216M $360M $315M $456M $716M $847M $949M $982M $576M
Accounts Payable 12-point trend, +91.2% $12M $4M $2M $4M $3M $5M $6M $12M $9M $8M $5M $6M
Short-term Debt 2-point trend, -100.0% · · $0 $43M · · · · · · · ·
Current Liabilities 12-point trend, -21.4% $37M $22M $23M $79M $35M $42M $123M $62M $80M $95M $76M $47M
Capital Leases 8-point trend, +3980000.00 $4M $5M $6M $7M $9M $8M $10M $0 · · · ·
Deferred Tax 11-point trend, +0.00 · $0 $2M $2M $3M $3M $3M $4M $16M $17M $22M $0
Other Non-current Liabilities 10-point trend, -80.8% $134.0K $0 · · $50.0K $100.0K $0 $3M $3M $4M $795.0K $699.0K
Total Liabilities 12-point trend, -19.4% $135M $79M $33M $90M $253M $247M $384M $337M $300M $380M $277M $167M
Long-term Debt 11-point trend, +798.6% $93M $0 · $43M $180M $172M $218M $212M $8M $8M $9M $10M
Total Debt 9-point trend, +798.6% $93M · · $43M $183M $172M $218M $212M $8M $8M · $10M
Paid-in Capital 12-point trend, +180.2% $2.36B $2.13B $2.08B $2.00B $2.02B $1.89B $1.75B $1.72B $1.40B $1.33B $1.25B $843M
Retained Earnings 12-point trend, -410.9% $-2.34B $-2.09B $-1.96B $-1.87B $-1.92B $-1.82B $-1.65B $-1.33B $-848M $-729M $-543M $-458M
AOCI 12-point trend, +275.0% $7.0K $12.0K $-2M $-3M $203.0K $4M $-27M $-29M $-16M $-36M $-13M $-4.0K
Stockholders' Equity 12-point trend, -94.6% $21M $39M $118M $126M $107M $67M $72M $363M $534M $560M $694M $385M
Liabilities + Equity 12-point trend, -73.0% $156M $145M $151M $216M $360M $315M $456M $716M $847M $949M $982M $576M
Shares Outstanding 12-point trend, +251.9% 353,910,926 292,869,097 248,919,096 208,150,021 206,739,874 187,663,207 163,274,880 160,020,466 122,087,040 118,688,770 116,658,886 100,557,932
Cash Flow 16
Annual Cash Flow data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, -69.3% $3M $5M $7M $11M $14M $18M $25M $33M $31M $25M $18M $10M
Stock-based Comp 12-point trend, -50.3% $11M $9M $10M $10M $14M $18M $19M $36M $42M $42M $39M $22M
Deferred Tax 12-point trend, +0.00 $0 $-2M $-479.0K $-150.0K $-167.0K $-156.0K $-4M $-21M $-3M $-3M $1M $0
Amort. of Intangibles 12-point trend, -70.0% $1M $3M $5M $5M $5M $5M $8M $12M $11M $15M $10M $4M
Other Non-cash 9-point trend, +400.8% $149M · · $-114M $9M $58M $146M $337M $-57M $67M · $30M
Operating Cash Flow 12-point trend, -342.3% $-88M $-68M $-67M $-65M $-56M $-77M $-136M $-124M $-104M $-49M $36M $-20M
CapEx 12-point trend, -68.7% $2M $9M $2M $5M $7M $8M $38M $42M $47M $32M $13M $6M
Investing Cash Flow 12-point trend, +94.1% $-2M $-21M $-3M $226M $-75M $28M $87M $-151M $104M $-28M $-259M $-26M
Debt Issued 11-point trend, +34533.6% $93M $0 $0 · $0 $0 $376.0K $220M $325.0K $547.0K $81.0K $268.0K
Net Debt Issued 9-point trend, +24590.2% $93M · · $-155M $-466.0K $-490.0K $-242.0K $219M $-194.0K $-654.0K · $-379.0K
Stock Issued 8-point trend, -355000.00 $-355.0K $31M $73M $0 · · · · $0 $0 $328M $0
Net Stock Activity 3-point trend, -355000.00 $-355.0K · · · · · · · $0 $0 · ·
Financing Cash Flow 12-point trend, +275.1% $90M $111M $30M $-155M $121M $33M $8M $310M $4M $12M $332M $24M
Net Change in Cash 12-point trend, +103.3% $717.0K $22M $-41M $5M $-9M $-16M $-42M $35M $6M $-66M $108M $-22M
Free Cash Flow 9-point trend, -242.5% $-90M · · $-70M $-63M $-85M $-174M $-166M $-151M $-88M · $-26M
Levered FCF 4-point trend, -547.0% · · · · · · · $-174M $-151M $-88M · $-27M
Profitability 7
Annual Profitability data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 4-point trend, -1073.3% -1141.1% · · · · · · · -59.7% -65.6% · -97.3%
Net Margin 7-point trend, -2175.3% -2588.2% · · 105.2% -88.7% -165.3% · · -50.7% -97.7% · -113.8%
Pretax Margin 7-point trend, -2071.8% -2588.2% · · -297.2% -93.3% -100.7% · · -56.1% -101.7% · -119.2%
EBITDA Margin 7-point trend, -1238.6% -1108.1% · · 40.0% 13.2% 17.0% · · -46.2% -52.7% · -82.8%
ROA 9-point trend, -965.0% -166.7% · · 9.8% -27.3% -44.3% -55.0% -65.2% -13.0% -19.3% · -15.7%
ROE 9-point trend, +14604.5% 3159.1% · · 21.1% -77.3% -271.3% -148.3% -113.6% -21.4% -29.8% · -21.8%
ROIC 5-point trend, -447.9% -96.9% · · · · · · -84.5% -24.9% -21.6% · -17.7%
Liquidity & Solvency 5
Annual Liquidity & Solvency data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 9-point trend, -16.1% 3.1 · · 1.5 4.5 3.5 1.9 4.6 1.9 3.3 · 3.7
Quick Ratio 9-point trend, -0.8% 2.7 · · 0.7 3.9 2.8 0.8 4.0 1.2 2.7 · 2.7
Debt / Equity 9-point trend, +16463.9% 4.5 · · 0.3 1.7 2.6 3.0 0.6 0.0 0.0 · 0.0
LT Debt / Equity 9-point trend, +19615.5% 4.5 · · 0.0 1.7 2.6 2.6 0.6 0.0 0.0 · 0.0
Interest Coverage 4-point trend, +43.6% · · · · · · · -59.3 -225.7 -145.4 · -105.0
Efficiency 2
Annual Efficiency data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 7-point trend, -53.2% 0.1 · · 0.1 0.3 0.3 · · 0.3 0.2 · 0.1
Receivables Turnover 7-point trend, -57.3% 4.0 · · 23.4 5.6 5.6 · · 11.2 8.2 · 9.4
Per Share 5
Annual Per Share data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, -98.5% $0.06 · · $0.61 $0.52 $0.36 $0.44 $2.27 $4.37 $4.72 · $3.83
Revenue / Share 3-point trend, -94.1% $0.03 · · $0.13 $0.53 · · · · · · ·
Cash Flow / Share 3-point trend, +0.5% $-0.28 · · $-0.32 $-0.28 · · · · · · ·
Cash / Share 9-point trend, -68.7% $0.09 · · $0.02 $0.21 $0.28 $0.40 $0.64 $0.56 $0.53 · $0.27
EPS (TTM) 12-point trend, -63.1% $-1.37 $-0.47 $-0.39 $0.14 $-0.47 $-1.02 $-2.09 $-1.54 $-1.54 $-1.54 $-0.74 $-0.84
Growth Rates 3
Annual Growth Rates data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +364.9% 146.7% -37.0% -76.9% 88.6% -55.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +31.3% -28.9% -35.0% -42.0% · · · · · · · · ·
Revenue CAGR 5Y -21.3% · · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for PGEN
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -86.5% $10M $4M $6M $27M $14M $32M $91M $151M $231M $191M $174M $72M
Net Income TTM 12-point trend, -206.3% $-251M $-126M $-96M $28M $-92M $-171M $-322M $-509M $-117M $-187M $-84M $-82M
Market Cap 9-point trend, -44.1% $1.48B · · $316M $767M $1.91B $895M $1.05B $1.41B $2.86B · $2.65B
Enterprise Value 9-point trend, -41.9% $1.47B · · $304M $835M $1.99B $1.04B $1.04B $1.34B $2.63B · $2.54B
P/E 12-point trend, +90.3% -3.1 -2.4 -3.4 10.9 -7.9 -10.0 -2.6 -4.2 -7.5 -15.6 -40.4 -31.3
P/S 9-point trend, +315.3% 152.8 · · 11.8 53.8 59.8 9.9 6.9 6.1 15.0 · 36.8
P/B 9-point trend, +928.8% 70.7 · · 2.5 7.1 28.5 12.5 2.9 2.6 5.1 · 6.9
P / Tangible Book 5-point trend, +1252.0% 592.5 8.0 6.5 7.0 43.8 · · · · · · ·
P / Cash Flow 9-point trend, +87.4% -16.8 · · -4.9 -13.8 -24.9 -6.6 -8.4 -13.5 -51.1 · -133.2
P / FCF 9-point trend, +83.7% -16.5 · · -4.5 -12.2 -22.6 -5.1 -6.3 -9.3 -32.6 · -100.9
EV / EBITDA 9-point trend, +67.8% -13.7 · · 28.2 60.7 113.4 41.7 -2.2 -12.6 -26.1 · -42.7
EV / FCF 9-point trend, +83.0% -16.4 · · -4.3 -13.3 -23.5 -6.0 -6.2 -8.9 -30.0 · -96.8
EV / Revenue 9-point trend, +331.2% 152.3 · · 11.3 58.5 62.1 11.4 6.9 5.8 13.8 · 35.3
Earnings Yield 12-point trend, -927.6% -32.8% -42.0% -29.1% 9.2% -12.7% -10.0% -38.1% -23.5% -13.4% -6.4% -2.5% -3.2%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $10M$4M$6M$27M$14M
Operating Margin % -1141.1%————
Net Income $-251M$-126M$-96M$28M$-92M
Diluted EPS $-1.37$-0.47$-0.39$0.14$-0.47
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 4.5——0.31.7
Current Ratio 3.1——1.54.5
Quick Ratio 2.7——0.73.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-90M——$-70M$-63M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 234 filers · $661.7M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
47 (+4 vs prior Q) 26 (+9 vs prior Q) 74 (+6 vs prior Q) 49 (+2 vs prior Q) +19.0M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Patient Capital Management, LLC $108,510,760 19,036,976 16.40% Shares
STATE STREET CORP $68,414,051 12,002,465 10.34% Shares
Diametric Capital, LP $52,838,578 9,269,926 7.98% Shares
VANGUARD CAPITAL MANAGEMENT LLC $45,065,112 7,906,160 6.81% Shares
TANG CAPITAL MANAGEMENT LLC $36,579,750 6,417,500 5.53% Shares
Boxer Capital Management, LLC $29,355,000 5,150,000 4.44% Shares
GEODE CAPITAL MANAGEMENT, LLC $24,765,144 4,343,981 3.74% Shares
IRIDIAN ASSET MANAGEMENT LLC/CT $22,982,189 4,031,963 3.47% Shares
Occam Crest Management LP $19,652,378 3,605,941 2.97% Shares
GOLDMAN SACHS GROUP INC $17,290,013 3,033,336 2.61% Shares
FMR LLC $14,640,068 2,568,433 2.21% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $12,603,680 2,211,172 1.90% Shares
MORGAN STANLEY $12,563,991 2,204,209 1.90% Shares
FIRST TRUST ADVISORS LP $11,483,556 2,014,659 1.74% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $10,192,940 1,788,235 1.54% Shares
Caption Management, LLC $9,690,000 1,700,000 1.46% Put option
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $8,640,362 1,515,853 1.31% Shares
Diametric Capital, LP $8,048,400 1,412,000 1.22% Call option
Woodline Partners LP $7,991,087 1,401,945 1.21% Shares
VANGUARD FIDUCIARY TRUST CO $7,386,904 1,295,948 1.12% Shares
Point72 Asset Management, L.P. $7,220,070 1,266,679 1.09% Shares
Caption Management, LLC $5,130,000 900,000 0.78% Shares
PRELUDE CAPITAL MANAGEMENT, LLC $5,028,922 882,267 0.76% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5,023,410 881,300 0.76% Call option
VANGUARD GROUP INC $4,949,421 1,184,072 0.75% Shares
CITADEL ADVISORS LLC $4,676,217 820,389 0.71% Shares
CITIGROUP INC $4,068,341 713,744 0.61% Shares
ESSEX INVESTMENT MANAGEMENT CO LLC $4,025,876 706,294 0.61% Shares
GMT Capital Corp $3,812,331 668,830 0.58% Shares
LexAurum Advisors, LLC $3,638,954 638,413 0.55% Shares
RENAISSANCE TECHNOLOGIES LLC $3,450,210 605,300 0.52% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,430,511 601,844 0.52% Shares
BANK OF AMERICA CORP /DE/ $3,030,816 531,722 0.46% Shares
Lansing Street Advisors $2,823,905 495,422 0.43% Shares
BARCLAYS PLC $2,806,687 492,401 0.42% Shares
CIBC Bancorp USA Inc. $2,788,736 489,252 0.42% Shares
Swiss National Bank $2,226,420 390,600 0.34% Shares
Cetera Investment Advisers $2,209,947 387,710 0.33% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $2,175,222 381,618 0.33% Shares
PEAK6 LLC $2,100,450 368,500 0.32% Call option
Squarepoint Ops LLC $2,013,650 353,272 0.30% Shares
Corient Private Wealth LP $1,908,373 334,802 0.29% Shares
ExodusPoint Capital Management, LP $1,778,001 311,930 0.27% Shares
JANE STREET GROUP, LLC $1,572,060 275,800 0.24% Call option
Virtus Investment Advisers, LLC $1,489,535 261,322 0.23% Shares
SIMPLEX TRADING, LLC $1,419,339 249,007 0.21% Shares
RHUMBLINE ADVISERS $1,347,743 236,448 0.20% Shares
BlackRock, Inc. $1,337,271 234,609 0.20% Shares
ALPINE WOODS CAPITAL INVESTORS, LLC $1,308,823 229,618 0.20% Shares
LPL Financial LLC $1,302,518 228,512 0.20% Shares
STATE OF WISCONSIN INVESTMENT BOARD $1,132,385 198,664 0.17% Shares
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $1,122,687 290,100 0.17% Shares
Rafferty Asset Management, LLC $1,122,626 196,952 0.17% Shares
Shay Capital LLC $1,083,000 190,000 0.16% Shares
WELLS FARGO & COMPANY/MN $1,003,975 176,136 0.15% Shares
WELLINGTON MANAGEMENT GROUP LLP $1,003,952 176,132 0.15% Shares
VICTORY CAPITAL MANAGEMENT INC $964,275 169,171 0.15% Shares
OSAIC HOLDINGS, INC. $902,052 158,257 0.14% Shares
VANGUARD ASSET MANAGEMENT, Ltd $891,999 156,491 0.13% Shares
Pathstone Holdings, LLC $891,349 156,377 0.13% Shares
ALLIANCEBERNSTEIN L.P. $877,631 226,778 0.13% Shares
CITADEL ADVISORS LLC $869,250 152,500 0.13% Call option
CIBC Private Wealth Group LLC $847,060 257,465 0.13% Shares
Voleon Capital Management LP $808,836 141,901 0.12% Shares
GLR Partners, LLC $798,963 140,169 0.12% Shares
TWO SIGMA INVESTMENTS, LP $780,729 136,970 0.12% Shares
DIADEMA PARTNERS LP $771,170 135,293 0.12% Shares
Bank of New York Mellon Corp $756,937 132,796 0.11% Shares
Aquatic Capital Management LLC $698,336 122,515 0.11% Shares
Shay Capital LLC $684,000 120,000 0.10% Call option
Vanguard Global Advisers, LLC $672,104 117,913 0.10% Shares
AXQ CAPITAL, LP $666,775 116,978 0.10% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $662,501 171,189 0.10% Shares
PRUDENTIAL FINANCIAL INC $661,029 115,970 0.10% Shares
MetLife Investment Management, LLC $643,638 112,919 0.10% Shares
Investment Insight Wealth Management, LLC $603,009 105,791 0.09% Shares
Mill Creek Capital Advisors, LLC $581,081 150,150 0.09% Shares
MILLENNIUM MANAGEMENT LLC $574,976 100,873 0.09% Shares
US BANCORP \DE\ $570,000 100,000 0.09% Shares
PROFUND ADVISORS LLC $568,877 99,803 0.09% Shares
HighTower Advisors, LLC $554,279 97,242 0.08% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $519,253 91,097 0.08% Shares
Integrated Quantitative Investments LLC $516,734 90,655 0.08% Shares
CARY STREET PARTNERS FINANCIAL LLC $499,280 87,593 0.08% Shares
Invesco Ltd. $438,330 76,900 0.07% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $414,390 72,700 0.06% Put option
CITADEL ADVISORS LLC $412,110 72,300 0.06% Put option
AMERICAN FINANCIAL GROUP INC $376,850 66,114 0.06% Shares
State of New Jersey Common Pension Fund D $358,769 62,942 0.05% Shares
HAP Trading, LLC $350,625 412,500 0.05% Call option
JANUS HENDERSON GROUP PLC $343,985 89,000 0.05% Shares
China Universal Asset Management Co., Ltd. $323,412 56,739 0.05% Shares
Cubist Systematic Strategies, LLC $320,775 97,500 0.05% Call option
Mitsubishi UFJ Asset Management Co., Ltd. $306,848 53,833 0.05% Shares
ARIZONA STATE RETIREMENT SYSTEM $306,164 53,713 0.05% Shares
TWO SIGMA ADVISERS, LP $305,558 73,100 0.05% Shares
Russell Investments Group, Ltd. $304,277 53,382 0.05% Shares
Police & Firemen's Retirement System of New Jersey $303,046 53,166 0.05% Shares
Pinnacle Financial Partners, Inc. $300,903 52,790 0.05% Shares
ENVESTNET ASSET MANAGEMENT INC $300,749 52,763 0.05% Shares

Company insiders 37 insiders · 12 officers · 10 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Helen Sabzevari President and CEO June 29, 2026 M 3,768,872 0 2 $-2,562,794
Harry Thomasian Jr. Chief Financial Officer July 31, 2026 S 254,535 2 4 $-1,861,741
Rick L. Sterling Chief Financial Officer Jan. 4, 2021 M 340,020 0 0 $0
Thomas Bostick Chief Operating Officer Jan. 4, 2020 M 74,280 0 0 $0
Phil Tennant Chief Commercial Officer May 28, 2026 S 139,369 1 1 $-110,506
Donald P. Lehr Chief Legal Officer May 28, 2026 S 755,461 0 1 $-127,011
Jeffrey Thomas Perez SVP, IP Affairs Aug. 9, 2024 P 743,097 0 0 $0
Bradford D. Osborne VP, Finance and Accounting April 21, 2021 A — 0 0 $0
Thomas D. Reed Chief Science Officer Jan. 4, 2020 M 148,888 0 0 $0
Robert F. Walsh III SVP, Energy & Fine Chem. June 30, 2019 M 28,816 0 0 $0
Nir Nimrodi Chief Business Officer Jan. 4, 2019 A 19,482 0 0 $0
Joel D Liffman SVP, Finance Jan. 4, 2019 A 99,315 0 0 $0
RANDAL J. KIRK Director March 30, 2026 S 12,262,741 0 28 $-60,808,573
Vinita D Gupta Director March 13, 2026 M 666,027 0 0 $0
Steven Frank Director March 13, 2026 M 1,226,391 0 0 $0
James S Turley Director March 13, 2026 M 685,417 0 0 $0
Nancy H Agee Director March 13, 2026 M 305,776 3 0 $167,651
Cesar L Alvarez Director March 13, 2026 M 782,909 0 0 $0
Jeffrey B Kindler Director March 13, 2026 M 202,100 0 3 $-1,458,937
Fred Hassan Director March 13, 2026 M 1,243,239 0 0 $0
Dean J Mitchell Director March 14, 2024 A 503,183 0 0 $0
Robert B Shapiro Director March 9, 2023 A 329,656 0 0 $0
Trading S.A. Ares 10% owner Oct. 13, 2021 S 20,647,152 0 0 $0
Rutul R Shah — Aug. 6, 2026 S 465,012 1 4 $-874,598
Andrew J. Last — Nov. 13, 2017 P 4,000 0 0 $0
Geno J Germano — Sept. 22, 2016 A — 0 0 $0
Suma Krishnan — Jan. 29, 2016 M 56,657 0 0 $0
Krish S Krishnan — Jan. 29, 2016 M 56,657 0 0 $0
Ena Chan Cratsenburg — Jan. 7, 2016 A — 0 0 $0
INTREXON CORP — Jan. 7, 2016 A — 0 0 $0
Joseph L Vaillancourt — Oct. 19, 2015 A — 0 0 $0
Corey Huck — Oct. 12, 2015 A — 0 0 $0
Samuel Broder — July 21, 2015 A — 0 0 $0
Jack A Bobo — July 20, 2015 A — 0 0 $0
Olivier Roger Jarry — June 11, 2015 A — 0 0 $0
Gregory Ian Frost — May 28, 2015 M 300,000 0 0 $0
HORNER LARRY D /FA — March 12, 2015 A 68,507 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 3 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
RANDAL J. KIRK, R.J. KIRK DECLARATION OF TRUST, THIRD SECURITY, LLC ×21 filings March 31, 2026 35.90% Amendment — SEC
Jan. 6, 2020 — Initial filing — SEC
Oct. 23, 2017 — Initial filing — SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 37 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBC · ETFis Series Trust I 0.83% 74,799 NS April 30, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.82% 25,796 SH Aug. 8, 2026 Daily
FYC · First Trust Exchange-Traded AlphaDE… 0.48% 1,206,971 NS April 30, 2026 N-PORT
IWC · iShares Trust 0.30% 656,858 SH Aug. 8, 2026 Daily
LABU · Direxion Shares ETF Trust 0.28% 343,575 NS April 30, 2026 N-PORT
FYX · First Trust Exchange-Traded AlphaDE… 0.18% 538,178 NS April 30, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.18% 19,403 SH Aug. 8, 2026 Daily
FAD · First Trust Exchange-Traded AlphaDE… 0.10% 112,542 NS April 30, 2026 N-PORT
IBB · iShares Trust 0.08% 1,154,248 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.08% 1,738,974 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.08% 292,277 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.08% 13,080 NS May 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.06% 206,995 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.04% 4,900,839 SH Aug. 8, 2026 Daily
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.04% 71,286 NS April 30, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.03% 1,111,545 SH Aug. 8, 2026 Daily
GSSC · Goldman Sachs ETF Trust 0.03% 65,610 NS May 31, 2026 N-PORT
ISCV · iShares Trust 0.03% 25,549 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.02% 78,008 NS April 30, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.02% 585,833 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.02% 8,486 NS May 31, 2026 N-PORT
ISCB · iShares Trust 0.02% 8,008 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.02% 839,393 NS May 31, 2026 N-PORT
ISCG · iShares Trust 0.02% 22,039 SH Aug. 8, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.01% 81,104 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.01% 6,636 NS May 31, 2026 N-PORT
WSML · iShares Trust 0.01% 10,653 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.01% 2,042,450 SH Aug. 8, 2026 Daily
URTY · ProShares Trust 0.01% 6,714 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.01% 126,693 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 6,924 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 168 NS May 31, 2026 N-PORT
IWV · iShares Trust 0.00% 61,530 SH Aug. 8, 2026 Daily
ITOT · iShares Trust 0.00% 286,791 SH Aug. 8, 2026 Daily
SCHB · SCHWAB STRATEGIC TRUST 0.00% 108,070 NS May 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 5,690,796 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 14,522 SH Aug. 8, 2026 Daily