Paul B Manning

CIK 1494695 · View on SEC EDGAR ↗

Insider Activist

First SEC filing: March 18, 2026 · Latest: June 8, 2026

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Insider at

Insider transactions

1 buys (P) 1 sells (S) Net: $2,273,180 + 44 non-open-market transactions below Avg return of open purchases vs now: 144.3% last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

44 other filings hidden
Date Ticker Code Shares Price Value Owned after Δ own A/D vs now
June 4, 2026 LQDA S 11,513 $63.13 $726,816 798,335 — — 15.5% (price as of 2026-08-20)
Feb. 23, 2026 CADL P 550,458 $5.45 $2,999,996 2,763,527 Indirect +24.87% Acquired 144.3% (price as of 2026-08-20)
Dec. 16, 2024 CADL P 750,000 $6.00 $4,500,000 1,303,752 Indirect +135.44% Acquired 121.9% (price as of 2026-08-20)
Dec. 16, 2024 CADL P 500,000 $6.00 $3,000,000 1,142,406 Indirect +77.83% Acquired 121.9% (price as of 2026-08-20)
Sept. 12, 2024 LQDA P 337,078 $8.90 $2,999,994 816,311 Indirect +70.34% Acquired 719.2% (price as of 2026-08-20)
Dec. 14, 2023 LQDA P 279,330 $7.16 $2,000,003 279,330 Direct — Acquired 918.2% (price as of 2026-08-20)
Nov. 17, 2023 TSHA P 100,000 $1.63 $163,000 16,566,667 Indirect +0.61% Acquired 274.2% (price as of 2026-08-20)
Aug. 16, 2023 TSHA P 16,466,667 $0.90 $14,820,000 16,466,667 Indirect — Acquired 577.8% (price as of 2026-08-20)
Oct. 31, 2022 TSHA P 1,500,000 $2.00 $3,000,000 1,642,202 Direct +1054.84% Acquired 205.0% (price as of 2026-08-20)
July 5, 2022 VRCA P 4,761,904 $2.10 $9,999,998 13,651,128 Direct +53.57% Acquired -76.2% (price as of 2026-08-20)
April 18, 2022 LQDA P 392,156 $5.10 $1,999,996 392,156 Direct — Acquired 1329.5% (price as of 2026-08-20)
Feb. 3, 2022 TSHA P 26,602 $7.84 $208,560 2,091,704 Indirect +1.29% Acquired -22.2% (price as of 2026-08-20)
Feb. 3, 2022 TSHA P 50,000 $7.84 $392,000 142,202 Direct +54.23% Acquired -22.2% (price as of 2026-08-20)
Feb. 2, 2022 TSHA P 22,000 $7.77 $170,940 22,000 Indirect — Acquired -21.5% (price as of 2026-08-20)
Feb. 2, 2022 TSHA P 45,000 $7.77 $349,650 2,065,102 Indirect +2.23% Acquired -21.5% (price as of 2026-08-20)
Feb. 2, 2022 TSHA P 58,000 $7.77 $450,660 92,202 Direct +169.58% Acquired -21.5% (price as of 2026-08-20)
Dec. 3, 2021 VRCA P 19,977 $9.22 $184,188 8,149,394 Direct +0.25% Acquired -94.6% (price as of 2026-08-20)
Dec. 2, 2021 VRCA P 30,023 $9.45 $283,717 8,129,417 Direct +0.37% Acquired -94.7% (price as of 2026-08-20)
Nov. 24, 2021 TSHA P 2,202 $13.19 $29,044 34,202 Direct +6.88% Acquired -53.8% (price as of 2026-08-20)
Nov. 23, 2021 TSHA P 20,000 $12.54 $250,800 32,000 Direct +166.67% Acquired -51.4% (price as of 2026-08-20)
July 29, 2021 CADL P 1,625,000 $8.00 $13,000,000 1,681,000 Direct +2901.79% Acquired 66.4% (price as of 2026-08-20)
July 29, 2021 CADL P 20,000 $7.30 $146,000 56,000 Direct +55.56% Acquired 82.4% (price as of 2026-08-20)
July 27, 2021 CADL P 36,000 $7.36 $264,960 36,000 Direct — Acquired 80.9% (price as of 2026-08-20)
July 6, 2021 ABOS P 312,500 $16.00 $5,000,000 3,352,693 Indirect +10.28% Acquired -80.7% (price as of 2026-08-20)
May 14, 2021 TSHA P 12,000 $20.98 $251,760 12,000 Direct — Acquired -70.9% (price as of 2026-08-20)
April 13, 2021 LQDA P 198,413 $2.52 $500,001 737,646 Indirect +36.80% Acquired 2793.1% (price as of 2026-08-20)
March 25, 2021 VRCA P 739,830 $14.75 $10,912,492 739,830 Indirect — Acquired -96.6% (price as of 2026-08-20)
Aug. 20, 2020 VRCA P 20,000 $9.09 $181,800 8,099,394 Direct +0.25% Acquired -94.5% (price as of 2026-08-20)
Aug. 18, 2020 VRCA P 10,000 $8.55 $85,500 1,481,719 Indirect +0.68% Acquired -94.2% (price as of 2026-08-20)
Aug. 17, 2020 VRCA P 6,000 $6.92 $41,520 1,471,719 Indirect +0.41% Acquired -92.8% (price as of 2026-08-20)
Aug. 14, 2020 VRCA P 50,000 $6.51 $325,500 1,465,719 Indirect +3.53% Acquired -92.3% (price as of 2026-08-20)
Aug. 13, 2020 VRCA P 108,500 $6.41 $695,485 1,415,719 Indirect +8.30% Acquired -92.2% (price as of 2026-08-20)
Oct. 10, 2019 VRCA P 6,900 $15.05 $103,845 8,079,394 Direct +0.09% Acquired -96.7% (price as of 2026-08-20)
Oct. 9, 2019 VRCA P 8,778 $14.06 $123,419 8,072,494 Direct +0.11% Acquired -96.4% (price as of 2026-08-20)
Oct. 8, 2019 VRCA P 5,208 $14.02 $73,016 8,063,716 Direct +0.06% Acquired -96.4% (price as of 2026-08-20)
Jan. 7, 2019 VRCA P 911 $11.99 $10,923 1,307,219 Indirect +0.07% Acquired -95.8% (price as of 2026-08-20)
Jan. 7, 2019 VRCA P 6,706 $11.55 $77,454 1,306,308 Indirect +0.52% Acquired -95.7% (price as of 2026-08-20)
Jan. 7, 2019 VRCA P 4,258 $10.41 $44,326 1,299,602 Indirect +0.33% Acquired -95.2% (price as of 2026-08-20)
Jan. 7, 2019 VRCA P 2,734 $11.99 $32,781 8,058,508 Direct +0.03% Acquired -95.8% (price as of 2026-08-20)
Jan. 7, 2019 VRCA P 20,116 $11.55 $232,340 8,055,774 Direct +0.25% Acquired -95.7% (price as of 2026-08-20)
Jan. 7, 2019 VRCA P 12,775 $10.41 $132,988 8,035,658 Direct +0.16% Acquired -95.2% (price as of 2026-08-20)
Nov. 13, 2018 VRCA P 55 $15.60 $858 1,295,344 Indirect 0.00% Acquired -96.8% (price as of 2026-08-20)
Nov. 13, 2018 VRCA P 55 $15.60 $858 8,022,883 Direct 0.00% Acquired -96.8% (price as of 2026-08-20)
Nov. 13, 2018 VRCA P 9,418 $14.94 $140,705 1,295,289 Indirect +0.73% Acquired -96.7% (price as of 2026-08-20)
Nov. 13, 2018 VRCA P 9,418 $14.94 $140,705 8,022,828 Direct +0.12% Acquired -96.7% (price as of 2026-08-20)
Nov. 13, 2018 VRCA P 10,527 $14.08 $148,220 1,285,871 Indirect +0.83% Acquired -96.4% (price as of 2026-08-20)
Nov. 13, 2018 VRCA P 10,527 $14.08 $148,220 8,013,410 Direct +0.13% Acquired -96.4% (price as of 2026-08-20)
Nov. 12, 2018 VRCA P 9,950 $13.96 $138,902 1,275,344 Indirect +0.79% Acquired -96.4% (price as of 2026-08-20)
Nov. 12, 2018 VRCA P 9,950 $13.96 $138,902 8,002,883 Direct +0.12% Acquired -96.4% (price as of 2026-08-20)
Nov. 12, 2018 VRCA P 5,150 $13.17 $67,826 1,265,394 Indirect +0.41% Acquired -96.2% (price as of 2026-08-20)
Nov. 12, 2018 VRCA P 5,150 $13.17 $67,826 7,992,933 Direct +0.06% Acquired -96.2% (price as of 2026-08-20)
Aug. 10, 2018 VRCA P 33,000 $15.08 $497,640 7,787,783 Direct +0.43% Acquired -96.7% (price as of 2026-08-20)
June 19, 2018 VRCA P 100,000 $15.00 $1,500,000 1,260,244 Indirect +8.62% Acquired -96.7% (price as of 2026-08-20)
June 19, 2018 VRCA P 200,000 $15.00 $3,000,000 7,987,783 Direct +2.57% Acquired -96.7% (price as of 2026-08-20)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II)

Options, RSUs and convertible securities reported on Form 4 Table II.

Date Ticker Security Underlying Exercise price Expiration Shares A/D
June 30, 2026 CADL Stock Option (Right to Buy) Common Stock (2,199) $10.30 June 30, 2036 2,199 Acquired
June 23, 2026 CADL Stock Option (Right to Buy) Common Stock (32,000) $9.08 June 23, 2036 32,000 Acquired
June 17, 2025 CADL Stock Option (Right to Buy) Common Stock (14,240) $4.94 June 17, 2035 14,240 Acquired
June 26, 2024 CADL Stock Option (Right to Buy) Common Stock (14,240) $5.71 June 26, 2034 14,240 Acquired
June 28, 2023 CADL Stock Option (Right to Buy) Common Stock (14,240) $1.22 June 28, 2033 14,240 Acquired
June 19, 2023 LQDA Non-Qualified Stock Option (right to buy) Common Stock (20,000) $8.63 June 19, 2033 20,000 Acquired
Oct. 13, 2022 CADL Stock Option (Right to Buy) Common Stock (14,240) $2.81 Oct. 13, 2032 14,240 Acquired
June 17, 2022 LQDA Non-Qualified Stock Option (right to buy) Common Stock (20,000) $4.86 June 17, 2032 20,000 Acquired
June 17, 2022 TSHA Stock Option (right to buy) Common Stock (15,500) $2.81 June 17, 2032 15,500 Acquired
Aug. 20, 2021 LQDA Non-Qualified Stock Option (right to buy) Common Stock (20,000) $2.59 Aug. 20, 2031 20,000 Acquired
July 29, 2021 CADL Series B Preferred Stock Common Stock (679,158) — — 1,669,303 Disposed
July 29, 2021 CADL Series B Preferred Stock Common Stock (553,752) — — 1,361,069 Disposed
July 29, 2021 CADL Series B Preferred Stock Common Stock (553,752) — — 1,361,069 Disposed
July 29, 2021 CADL Series B Preferred Stock Common Stock (679,158) — — 1,669,303 Disposed
July 6, 2021 ABOS Series B Preferred Stock Common Stock (657,985) — — 657,985 Disposed
July 6, 2021 ABOS Series B Preferred Stock Common Stock (1,315,969) — — 1,315,969 Disposed
July 6, 2021 ABOS Series A-1 Preferred Stock Common Stock (1,634,515) — — 1,634,515 Disposed
June 17, 2021 TSHA Stock Option (right to buy) Common Stock (15,500) $25.04 June 17, 2031 15,500 Acquired
March 24, 2021 LQDA Non-Qualified Stock Option (right to buy) Common Stock (21,385) $2.51 March 24, 2031 21,385 Acquired
Nov. 18, 2020 LQDA Non-Qualified Stock Option (right to buy) Common Stock (30,000) $3.38 Nov. 18, 2030 30,000 Acquired
Sept. 28, 2020 TSHA Series B Preferred Stock Common Stock (11,944) — — 10,963 Disposed
Sept. 28, 2020 TSHA Series A Preferred Stock Common Stock (2,008,158) — — 1,843,193 Disposed
Sept. 28, 2020 TSHA Series A Preferred Stock Common Stock (3,275,205) — — 3,006,155 Disposed
Sept. 23, 2020 TSHA Stock Option (right to buy) Common Stock (31,000) $20.00 Sept. 23, 2030 31,000 Acquired
June 19, 2018 VRCA Series A Convertible Preferred Stock Common Stock (256,634) — — 256,634 Disposed
June 19, 2018 VRCA Series A Convertible Preferred Stock Common Stock (1,132,900) — — 1,132,900 Disposed
June 19, 2018 VRCA Series A Convertible Preferred Stock Common Stock (7,754,783) — — 7,754,783 Disposed

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 18 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date Ticker Security Shares Ownership
July 26, 2021 CADL Series B Preferred Stock→ Common Stock (679,158) 679,158 Indirect
July 26, 2021 CADL Series B Preferred Stock→ Common Stock (553,752) 553,752 Indirect
July 26, 2021 CADL Warrants to purchase Common Stock→ Common Stock (679,158) 679,158 Indirect
July 26, 2021 CADL Warrants to purchase Common Stock→ Common Stock (553,752) 553,752 Indirect
June 30, 2021 ABOS Common Stock 89,709 Indirect
June 30, 2021 ABOS Series A-1 Preferred Stock→ Common Stock (1,634,515) 1,634,515 Indirect
June 30, 2021 ABOS Series B Preferred Stock→ Common Stock (1,315,969) 1,315,969 Indirect
June 30, 2021 ABOS Series B Preferred Stock→ Common Stock (657,985) 657,985 Indirect
Nov. 19, 2020 LQDA Common Stock 3,921,075 Indirect
Nov. 19, 2020 LQDA Common Stock 539,233 Indirect
Nov. 19, 2020 LQDA Common Stock 479,233 Indirect
Sept. 23, 2020 TSHA Series A Preferred Stock→ Common Stock (3,275,205) 3,275,205 Indirect
Sept. 23, 2020 TSHA Series A Preferred Stock→ Common Stock (2,008,158) 2,008,158 Indirect
Sept. 23, 2020 TSHA Series B Preferred Stock→ Common Stock (11,944) 11,944 Indirect
June 14, 2018 VRCA Common Stock 27,344 Indirect
June 14, 2018 VRCA Series A Convertible Preferred Stock→ Common Stock (7,754,783) 7,754,783 Direct
June 14, 2018 VRCA Series A Convertible Preferred Stock→ Common Stock (1,132,900) 1,132,900 Indirect
June 14, 2018 VRCA Series A Convertible Preferred Stock→ Common Stock (256,634) 256,634 Indirect