Insider at

04

Insider transactions

05
0 buys (P) 50 sells (S) Net: $-34,273,502 + 25 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

25 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Sept. 4, 2026 KRYS S 520 $354.54 $184,361 1,326,625 Direct -0.04% Disposed -9.1% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 2,006 $355.57 $713,273 1,324,619 Direct -0.15% Disposed -9.4% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,267 $356.37 $1,164,261 1,321,352 Direct -0.25% Disposed -9.6% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,962 $357.57 $1,416,692 1,317,390 Direct -0.30% Disposed -9.9% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,180 $358.42 $1,139,776 1,314,210 Direct -0.24% Disposed -10.1% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 3,392 $359.39 $1,219,051 1,310,818 Direct -0.26% Disposed -10.3% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 2,320 $360.47 $836,290 1,308,498 Direct -0.18% Disposed -10.6% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 1,242 $361.61 $449,120 1,307,256 Direct -0.09% Disposed -10.9% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 1,992 $362.65 $722,399 1,305,264 Direct -0.15% Disposed -11.1% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 565 $363.34 $205,287 1,304,699 Direct -0.04% Disposed -11.3% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 1,329 $364.48 $484,394 1,303,370 Direct -0.10% Disposed -11.6% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 826 $365.41 $301,829 1,302,544 Direct -0.06% Disposed -11.8% (price as of 2026-10-02)
Sept. 4, 2026 KRYS S 10b5-1 399 $366.56 $146,257 1,302,145 Direct -0.03% Disposed -12.1% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 240 $311.65 $74,796 1,378,155 Direct -0.02% Disposed 3.4% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 2,039 $310.94 $634,007 1,378,395 Direct -0.15% Disposed 3.6% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 2,801 $309.95 $868,170 1,380,434 Direct -0.20% Disposed 4.0% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 3,803 $308.89 $1,174,709 1,383,235 Direct -0.27% Disposed 4.3% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 12,729 $307.81 $3,918,113 1,387,038 Direct -0.91% Disposed 4.7% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 1,348 $307.09 $413,957 1,399,767 Direct -0.10% Disposed 4.9% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 480 $305.86 $146,813 1,401,115 Direct -0.03% Disposed 5.4% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 400 $304.89 $121,956 1,401,595 Direct -0.03% Disposed 5.7% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 247 $303.17 $74,883 1,401,995 Direct -0.02% Disposed 6.3% (price as of 2026-10-02)
June 4, 2026 KRYS S 10b5-1 593 $302.25 $179,234 1,402,242 Direct -0.04% Disposed 6.6% (price as of 2026-10-02)
June 4, 2026 KRYS S 320 $300.75 $96,240 1,402,835 Direct -0.02% Disposed 7.2% (price as of 2026-10-02)
March 4, 2026 KRYS S 407 $257.32 $104,729 1,427,748 Direct -0.03% Disposed 25.2% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 589 $258.54 $152,280 1,427,159 Direct -0.04% Disposed 24.7% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 668 $259.61 $173,419 1,426,491 Direct -0.05% Disposed 24.1% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 3,667 $260.37 $954,777 1,422,824 Direct -0.26% Disposed 23.8% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 2,931 $261.41 $766,193 1,419,893 Direct -0.21% Disposed 23.3% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 1,938 $262.35 $508,434 1,417,955 Direct -0.14% Disposed 22.8% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 2,248 $263.58 $592,528 1,415,707 Direct -0.16% Disposed 22.3% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 4,852 $264.64 $1,284,033 1,410,855 Direct -0.34% Disposed 21.8% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 6,000 $265.16 $1,590,960 1,404,855 Direct -0.43% Disposed 21.5% (price as of 2026-10-02)
March 4, 2026 KRYS S 10b5-1 1,700 $266.42 $452,914 1,403,155 Direct -0.12% Disposed 21.0% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 700 $214.25 $149,975 1,438,011 Direct -0.05% Disposed 50.4% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 600 $215.49 $129,294 1,437,411 Direct -0.04% Disposed 49.6% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 1,400 $216.97 $303,758 1,436,011 Direct -0.10% Disposed 48.5% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 3,593 $218.83 $786,256 1,432,418 Direct -0.25% Disposed 47.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 5,419 $219.68 $1,190,446 1,426,999 Direct -0.38% Disposed 46.7% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 2,627 $220.52 $579,306 1,424,372 Direct -0.18% Disposed 46.1% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 10,461 $221.82 $2,320,459 1,413,911 Direct -0.73% Disposed 45.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 200 $222.38 $44,476 1,413,711 Direct -0.01% Disposed 44.9% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 956 $214.28 $204,852 1,507,100 Indirect -0.06% Disposed 50.4% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 344 $215.48 $74,125 1,506,756 Indirect -0.02% Disposed 49.6% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 1,600 $217.04 $347,264 1,505,156 Indirect -0.11% Disposed 48.5% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 2,577 $218.72 $563,641 1,502,579 Indirect -0.17% Disposed 47.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 5,693 $219.53 $1,249,784 1,496,886 Indirect -0.38% Disposed 46.8% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 2,625 $220.34 $578,392 1,494,261 Indirect -0.18% Disposed 46.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 10,505 $221.78 $2,329,799 1,483,756 Indirect -0.70% Disposed 45.3% (price as of 2026-10-02)
Dec. 4, 2025 KRYS S 10b5-1 700 $222.20 $155,540 1,483,056 Indirect -0.05% Disposed 45.0% (price as of 2026-10-02)
July 16, 2025 KRYS S 10b5-1 1,529 $150.00 $229,350 1,438,711 Direct -0.11% Disposed 114.9% (price as of 2026-10-02)
July 16, 2025 KRYS S 10b5-1 1,389 $150.00 $208,350 1,508,056 Indirect -0.09% Disposed 114.9% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 2,236 $150.68 $336,920 1,441,040 Direct -0.15% Disposed 113.9% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 800 $151.79 $121,432 1,440,240 Direct -0.06% Disposed 112.3% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 2,184 $150.68 $329,085 1,510,345 Indirect -0.14% Disposed 113.9% (price as of 2026-10-02)
July 15, 2025 KRYS S 10b5-1 900 $151.79 $136,611 1,509,445 Indirect -0.06% Disposed 112.3% (price as of 2026-10-02)
July 14, 2025 KRYS S 10b5-1 13,335 $150.29 $2,004,117 1,443,376 Direct -0.92% Disposed 114.4% (price as of 2026-10-02)
July 14, 2025 KRYS S 10b5-1 100 $151.00 $15,100 1,443,276 Direct -0.01% Disposed 113.4% (price as of 2026-10-02)
July 14, 2025 KRYS S 10b5-1 13,400 $150.30 $2,014,020 1,512,529 Indirect -0.88% Disposed 114.4% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 6,500 $150.23 $976,495 1,457,011 Direct -0.44% Disposed 114.5% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 300 $151.39 $45,417 1,456,711 Direct -0.02% Disposed 112.9% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 6,627 $150.22 $995,508 1,526,229 Indirect -0.43% Disposed 114.5% (price as of 2026-10-02)
July 10, 2025 KRYS S 10b5-1 300 $151.39 $45,417 1,525,929 Indirect -0.02% Disposed 112.9% (price as of 2026-10-02)
July 9, 2025 KRYS S 10b5-1 200 $150.14 $30,028 1,463,511 Direct -0.01% Disposed 114.7% (price as of 2026-10-02)
July 9, 2025 KRYS S 10b5-1 200 $150.07 $30,014 1,532,856 Indirect -0.01% Disposed 114.8% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,639 $175.97 $288,415 1,487,072 Direct -0.11% Disposed 83.1% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 4,579 $176.88 $809,934 1,482,493 Direct -0.31% Disposed 82.2% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 10,937 $177.66 $1,943,067 1,471,556 Direct -0.74% Disposed 81.4% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 6,514 $178.76 $1,164,443 1,465,042 Direct -0.44% Disposed 80.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,331 $179.55 $238,981 1,463,711 Direct -0.09% Disposed 79.5% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,100 $175.83 $193,413 1,556,956 Indirect -0.07% Disposed 83.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 4,944 $176.80 $874,099 1,552,012 Indirect -0.32% Disposed 82.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 10,931 $177.62 $1,941,564 1,541,081 Indirect -0.70% Disposed 81.4% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 6,769 $178.77 $1,210,094 1,534,312 Indirect -0.44% Disposed 80.3% (price as of 2026-10-02)
March 13, 2025 KRYS S 10b5-1 1,256 $179.57 $225,540 1,533,056 Indirect -0.08% Disposed 79.5% (price as of 2026-10-02)

Showing latest 100 of 298 transactions

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
Feb. 27, 2026 KRYS Performance Stock Units Common Stock (22,500) · · 22,500 Disposed
Feb. 27, 2026 KRYS Restricted Stock Units Common Stock (4,000) · · 4,000 Disposed
Feb. 27, 2026 KRYS Stock Option (Right to Buy) Common Stock (18,100) $275.64 Feb. 26, 2036 18,100 Acquired
Feb. 27, 2026 KRYS Restricted Stock Units Common Stock (7,256) · · 7,256 Acquired
Feb. 27, 2026 KRYS Performance Stock Units Common Stock (43,536) · · 43,536 Acquired
Feb. 28, 2025 KRYS Performance Stock Units Common Stock (7,500) · · 7,500 Disposed
Feb. 28, 2025 KRYS Performance Stock Units Common Stock (22,500) · · 22,500 Disposed
Feb. 28, 2025 KRYS Stock Option (Right to Buy) Common Stock (25,000) $179.25 Feb. 28, 2035 25,000 Acquired
Feb. 28, 2025 KRYS Restricted Stock Units Common Stock (16,000) · · 16,000 Acquired
Feb. 29, 2024 KRYS Performance Stock Units Common Stock (45,000) · · 45,000 Acquired
Feb. 28, 2024 KRYS Performance Stock Units Common Stock (7,500) · · 7,500 Disposed
Feb. 28, 2023 KRYS Stock Option (Right to Buy) Common Stock (30,000) $81.91 Feb. 28, 2033 30,000 Acquired
Feb. 28, 2023 KRYS Performance Stock Units Common Stock · · 15,000 Acquired
Feb. 28, 2022 KRYS Stock Option (Right to Buy) Common Stock (50,000) $63.55 Feb. 28, 2032 50,000 Acquired
Feb. 26, 2021 KRYS Stock Option (Right to Buy) Common Stock (42,600) $78.89 Feb. 26, 2025 42,600 Acquired
Sept. 22, 2017 KRYS Series A Convertible Preferred Stock Common Stock (112,162) · · 112,162 Disposed
Jan. 29, 2016 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (14,657) $6.88 Jan. 3, 2022 14,657 Disposed
Jan. 28, 2016 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (14,657) $6.88 Dec. 5, 2021 14,657 Disposed
May 18, 2015 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (42,000) $7.12 Jan. 3, 2022 42,000 Disposed
May 18, 2015 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (42,000) $7.12 Dec. 5, 2021 42,000 Disposed
March 20, 2014 PGEN Option to Purchase Common Stock (Right to Buy) Common Stock (300,000) $30.72 March 20, 2024 300,000 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 5 holdings

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Sept. 25, 2017 KRYS Series A Convertible Preferred Stock [F1]→ Common Stock · Indirect
Sept. 19, 2017 KRYS Common Stock 1,835,249 Direct
Sept. 19, 2017 KRYS Common Stock 1,835,249 Indirect
Sept. 19, 2017 KRYS Series A Convertible Preferred Stock [F2] 112,162 Indirect
Aug. 7, 2013 PGEN Option to Purchase Common Stock→ Common Stock (85,714) 85,714 Direct

Compensation (DEF 14A)

08

Matched by name from proxy statements (DEF 14A) — verify against the filing.

Fiscal yearSalaryBonusStock awards Option awardsNon-equity incentivePension changeOtherTotal
2020 $392,215 $140,054 · · · · · $532,269
2019 $305,642 · · · · · · $305,642
2018 $366,994 $128,450 · · · · · $495,444

Figures from the Summary Compensation Table of the company's proxy statement (DEF 14A). Compensation is not a recommendation.