ACRS Aclaris Therapeutics, Inc. - Common Stock
$6,36
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 6, 2026
Rango 52S
$2–$7
97% of range
Calificación del Analista
STRONG BUY
18 analysts
Precio Objetivo
$10
+60% upside
P/E (TTM)
-12.0
ROE
-55.3%
Margen de Beneficio Neto
-829.6%
ACRS Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$6.36
Capitalización Bursátil
$766M
P/E (TTM)
-12.0
BPA (TTM)
$-0.53
Ingresos (TTM)
$8M
Rendimiento div.
—
ROE
-55.3%
Deuda/Capital
—
Rango 52S
$2 – $7
ACRS Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$8M
2017-12-31
→
2025-12-31
BPA
$-0.53
2019-12-31
→
2025-12-31
Flujo de caja libre
$-47M
2016-12-31
→
2025-12-31
Márgenes
-829.6%
2017-12-31
→
2018-12-31
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
ACRS
Mediana de Pares
P/E (TTM)
-12.0
11.7
P/S (TTM) (P/V (TTM))
97.9
5.4
P/B (P/C)
7.4
3.2
Price / FCF (Precio / FCF)
-16.2
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
ACRS
Mediana de Pares
Operating Margin (Margen Operativo)
-975.9%
—
Net Profit Margin (Margen de Beneficio Neto)
-829.6%
-33.0%
ROA
-34.1%
-25.6%
ROE
-55.3%
-21.8%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
ACRS
Mediana de Pares
Current Ratio (Ratio corriente)
3.4
4.1
Quick Ratio (Ratio Rápido)
0.7
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
ACRS
Mediana de Pares
Revenue YoY (Ingresos interanuales)
-58.2%
—
Revenue CAGR 3Y (Ingresos CAGR 3A)
-35.9%
—
Revenue CAGR 5Y (Ingresos CAGR 5A)
3.8%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
ACRS
Mediana de Pares
ACRS Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
18 analistas
- Compra fuerte 8 44,4%
- Compra 8 44,4%
- Mantener 2 11,1%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
10 analistas · 2026-08-16
Mediana
$10.00
Ahora
$6.36
Mín
$4.00
Máx
$16.00
Objetivo mediano
$10.00
+57,2%
Objetivo medio
$10.20
+60,4%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.01%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.15 | $-0.16 | 0.01% |
| 31 de marzo de 2026 | $-0.15 | $-0.16 | 0.01% |
| 31 de diciembre de 2025 | $-0.16 | $-0.15 | -0.01% |
| 30 de septiembre de 2025 | $-0.12 | $-0.14 | 0.02% |
| 30 de junio de 2025 | $-0.13 | $-0.14 | 0.01% |
| 31 de marzo de 2025 | $-0.12 | $-0.12 | -0.00% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| ACRS | $363M | -5.7 | -58.2% | -829.6% | -55.3% | — |
| LXRX | $421M | -8.2 | 60.2% | -101.1% | -39.7% | — |
| PCRX | $1.06B | 161.8 | 3.6% | 0.97% | 0.97% | — |
| COLL | $1.47B | 26.8 | 23.6% | 8.1% | 23.5% | 59.4% |
| SGP | — | — | — | — | 50.0% | — |
| AMPH | $1.22B | 13.2 | -1.7% | 13.6% | 12.7% | 49.5% |
| PHAT | $1.18B | -5.5 | 216.9% | -126.4% | 52.4% | 87.1% |
| CRMD | $922M | 5.7 | 617.0% | 52.3% | 52.1% | 88.5% |
| ARVN | $753M | -10.4 | -0.30% | -30.8% | -15.5% | — |
| LLY | — | 46.8 | 44.7% | 31.7% | 101.2% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 17
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $8M | $19M | $31M | $30M | $7M | $6M | $4M | $6M | $2M | |
| Cost of Revenue | $2M | $3M | $3M | $4M | $5M | $5M | $4M | $4M | $1M | |
| Gross Profit | · | · | · | · | · | · | · | $3M | $476.0K | |
| R&D Expense | $53M | $34M | $98M | $78M | $44M | $29M | $64M | $61M | $36M | |
| SG&A Expense | $22M | $22M | $32M | $25M | $24M | $21M | $28M | $26M | $19M | |
| Operating Expenses | $84M | $161M | $129M | $120M | $96M | $57M | $115M | $91M | $56M | |
| Operating Income | $-76M | $-142M | $-97M | $-90M | $-90M | $-51M | $-111M | $-85M | $-54M | |
| Interest Income | $8M | $8M | $9M | · | · | · | · | · | · | |
| Other Non-op | $11M | $10M | $9M | $3M | $-1M | $-424.0K | $-2M | $3M | $2M | |
| Pretax Income | $-65M | $-132M | $-89M | $-87M | $-91M | $-51M | $-114M | $-82M | $-70M | |
| Income Tax | · | · | $-367.0K | · | · | $-182.0K | · | · | $-2M | |
| Net Income | $-65M | $-132M | $-88M | $-87M | $-91M | $-51M | $-161M | $-133M | $-69M | |
| EPS (Basic) | $-0.53 | $-1.71 | $-1.27 | $-1.33 | $-1.60 | $-1.20 | $-3.90 | · | · | |
| EPS (Diluted) | $-0.53 | $-1.71 | $-1.27 | $-1.33 | $-1.60 | $-1.20 | $-3.90 | · | · | |
| Shares (Basic) | 122,564,741 | 77,296,665 | 69,808,855 | 65,213,944 | 56,730,583 | 42,539,293 | 41,323,921 | · | · | |
| Shares (Diluted) | 122,564,741 | 77,296,665 | 69,808,855 | 65,213,944 | 56,730,583 | 42,539,293 | 41,323,921 | · | · | |
| EBITDA | $-76M | $-141M | $-96M | $-89M | $-89M | $-50M | $-105M | $-134M | $-72M |
Balance general 27
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $20M | $25M | $40M | $45M | $27M | $22M | $34M | $168M | $20M | |
| Receivables | · | $318.0K | $298.0K | $484.0K | $623.0K | $772.0K | $704.0K | $563.0K | $481.0K | |
| Inventory | · | · | · | · | · | · | $0 | $791.0K | · | |
| Prepaid Expense | · | $12M | $9M | $13M | $13M | $3M | $3M | $5M | $6M | |
| Current Assets | $96M | $126M | $129M | $232M | $205M | $57M | $84M | $179M | $200M | |
| PP&E (Net) | $761.0K | $1M | $2M | $1M | $1M | $2M | $2M | $2M | $2M | |
| PP&E (Gross) | · | $6M | $6M | $5M | $5M | $4M | $5M | $4M | $3M | |
| Accum. Depreciation | · | $5M | $4M | $4M | $3M | $3M | $2M | $1M | $480.0K | |
| Goodwill | · | · | · | · | · | · | · | $19M | $19M | |
| Intangibles | · | · | $269.0K | $7M | $7M | $7M | $7M | $7M | $7M | |
| Other Non-current Assets | $3M | $3M | $4M | $3M | $4M | $5M | $5M | $332.0K | $279.0K | |
| Total Assets | $160M | $220M | $197M | $255M | $251M | $71M | $98M | $276M | $244M | |
| Accounts Payable | $13M | $5M | $9M | $10M | $10M | $5M | $10M | $12M | $8M | |
| Accrued Liabilities | $9M | $20M | $19M | $9M | $10M | $6M | $8M | $8M | $5M | |
| Current Liabilities | $29M | $32M | $31M | $22M | $23M | $15M | $22M | $27M | $13M | |
| Capital Leases | $2M | $2M | $3M | $2M | $2M | $3M | $4M | · | · | |
| Deferred Tax | · | · | · | $367.0K | $367.0K | $367.0K | $549.0K | $549.0K | $549.0K | |
| Other Non-current Liabilities | $2M | $4M | $3M | $2M | $2M | $3M | $4M | $476.0K | $558.0K | |
| Total Liabilities | $57M | $65M | $40M | $57M | $54M | $33M | $28M | $60M | $18M | |
| Long-term Debt | · | · | · | · | · | $11M | · | $30M | · | |
| Common Stock | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | · | · | · | · | |
| Paid-in Capital | $1.07B | $1.06B | $928M | $881M | $793M | $542M | $524M | $507M | $385M | |
| Retained Earnings | $-968M | $-903M | $-771M | $-682M | $-595M | $-505M | $-454M | $-292M | $-159M | |
| AOCI | $610.0K | $97.0K | $-106.0K | $-897.0K | $-224.0K | $-94.0K | $-66.0K | $-69.0K | $-246.0K | |
| Stockholders' Equity | $103M | $156M | $157M | $198M | $197M | $38M | $70M | $215M | $225M | |
| Liabilities + Equity | $160M | $220M | $197M | $255M | $251M | $71M | $98M | $276M | $244M | |
| Shares Outstanding | 120,499,433 | 107,850,124 | 70,894,889 | 66,688,647 | 61,228,446 | 45,109,314 | 41,485,638 | 41,210,725 | 30,856,505 |
Flujo de Efectivo 11
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $454.0K | $807.0K | $863.0K | $797.0K | $923.0K | $1M | $6M | $2M | $402.0K | |
| Stock-based Comp | $12M | $11M | $21M | $15M | $14M | $11M | $16M | $20M | $14M | |
| Amort. of Intangibles | · | · | $75.0K | $75.0K | $75.0K | $75.0K | $75.0K | $75.0K | $31.0K | |
| Restructuring | · | · | $3M | · | · | · | · | · | · | |
| Other Non-cash | $5M | $100M | $-11M | $4M | $24M | $-149.0K | $42M | $10M | $-972.0K | |
| Operating Cash Flow | $-47M | $-20M | $-78M | $-68M | $-52M | $-39M | $-96M | $-101M | $-55M | |
| CapEx | $111.0K | $121.0K | $1M | $605.0K | $308.0K | $453.0K | $2M | $1M | $1M | |
| Investing Cash Flow | $48M | $-70M | $46M | $13M | $-168M | $6M | $106M | $9M | $-56M | |
| Financing Cash Flow | $-6M | $75M | $27M | $73M | $225M | $18M | $-30M | $128M | $100M | |
| Net Change in Cash | $-5M | $-15M | $-5M | $18M | $5M | $-14M | $-21M | $37M | $-10M | |
| Free Cash Flow | $-47M | $-20M | $-80M | $-68M | $-52M | $-39M | $-98M | $-102M | $-56M |
Rentabilidad 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | · | · | · | · | · | · | · | 32.1% | 28.3% | |
| Operating Margin | -975.9% | -758.2% | -311.6% | -302.0% | -1327.1% | -785.4% | -2627.3% | -1341.9% | -4303.2% | |
| Net Margin | -829.6% | -705.5% | -283.2% | -292.1% | -1344.0% | -787.0% | -3817.2% | -1315.4% | -4071.5% | |
| Pretax Margin | -829.6% | -705.5% | -284.3% | -292.1% | -1344.0% | -792.0% | -3817.2% | -1315.4% | -4180.2% | |
| EBITDA Margin | -970.1% | -753.9% | -308.8% | -299.3% | -1313.4% | -765.0% | -2475.7% | -1323.3% | -4279.3% | |
| ROA | -34.1% | -63.2% | -39.1% | -34.4% | -56.4% | -60.3% | -86.3% | -51.1% | -32.7% | |
| ROE | -55.3% | -92.5% | -56.5% | -41.6% | -43.9% | -130.1% | -207.9% | -73.5% | -34.7% | |
| ROIC | · | · | -61.7% | · | · | -134.8% | · | · | -31.3% |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.4 | 4.0 | 4.2 | 10.6 | 8.9 | 3.9 | 3.7 | 6.6 | 15.7 | |
| Quick Ratio | 0.7 | 0.8 | 1.3 | 2.1 | 1.2 | 1.5 | 3.4 | 6.3 | 1.6 |
Eficiencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | 0.1 | 0.1 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | |
| Inventory Turnover | · | · | · | · | · | · | 10.3 | 17.3 | · | |
| Receivables Turnover | · | 60.8 | 79.9 | 53.8 | 9.7 | 8.8 | 6.7 | 3.8 | 7.0 |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -58.2% | -40.1% | 5.0% | 340.1% | 4.3% | · | · | · | · | |
| Revenue CAGR 3Y | -35.9% | 40.4% | 68.9% | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 3.8% | · | · | · | · | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $8M | $19M | $31M | $30M | $7M | $6M | $4M | $6M | $2M | |
| Net Income TTM | $-65M | $-132M | $-88M | $-87M | $-91M | $-51M | $-161M | $-133M | $-69M | |
| Market Cap | $363M | $267M | $74M | $1.05B | $890M | $292M | $78M | $305M | $760M | |
| P/E | -5.7 | -1.5 | -0.8 | -11.8 | -9.1 | -5.4 | -0.5 | · | · | |
| P/S | 46.3 | 14.3 | 2.4 | 35.3 | 131.7 | 45.0 | 18.5 | 49.5 | 451.8 | |
| P/B | 3.5 | 1.7 | 0.5 | 5.3 | 4.5 | 7.8 | 1.1 | 1.4 | 3.4 | |
| P / Tangible Book | 3.5 | 1.7 | 0.5 | 5.5 | 4.7 | 9.6 | · | · | · | |
| P / Cash Flow | -7.7 | -13.3 | -1.0 | -15.5 | -17.1 | -7.6 | -0.8 | -3.0 | -13.9 | |
| P / FCF | -7.7 | -13.2 | -0.9 | -15.4 | -17.0 | -7.5 | -0.8 | -3.0 | -13.6 | |
| Earnings Yield | -17.6% | -69.0% | -121.0% | -8.4% | -11.0% | -18.6% | -206.3% | · | · |
Estado de resultados 15
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $2M | $2M | $1M | $3M | $2M | $1M | $9M | $4M | $3M | $2M | $18M | $9M | $2M | $3M | $8M | $19M | |
| Cost of Revenue | $218.0K | $395.0K | $532.0K | $538.0K | $515.0K | $506.0K | $705.0K | $654.0K | $624.0K | $809.0K | $725.0K | $848.0K | $1M | $808.0K | $877.0K | $923.0K | |
| R&D Expense | $18M | $16M | $17M | $13M | $11M | $12M | $9M | $6M | $9M | $10M | $27M | $24M | $25M | $23M | $21M | $24M | |
| SG&A Expense | $6M | $7M | $6M | $5M | $5M | $6M | $5M | $6M | $5M | $7M | $8M | $7M | $8M | $9M | $7M | $6M | |
| Operating Expenses | $26M | $24M | $24M | $20M | $20M | $20M | $109M | $15M | $16M | $21M | $22M | $41M | $34M | $32M | $37M | $40M | |
| Operating Income | $-24M | $-22M | $-23M | $-17M | $-18M | $-18M | $-100M | $-10M | $-13M | $-19M | $-4M | $-32M | $-32M | $-30M | $-29M | $-21M | |
| Interest Income | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | · | · | · | |
| Other Non-op | $3M | $2M | $3M | $3M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $922.0K | |
| Pretax Income | · | · | $-20M | $-15M | $-15M | $-15M | $-97M | $-8M | $-11M | $-17M | · | · | · | · | · | · | |
| Net Income | $-22M | $-20M | $-20M | $-15M | $-15M | $-15M | $-97M | $-8M | $-11M | $-17M | $-1M | $-29M | $-30M | $-28M | $-28M | $-20M | |
| EPS (Basic) | $-0.15 | $-0.15 | $-0.16 | $-0.12 | $-0.13 | $-0.12 | $-1.21 | $-0.11 | $-0.15 | $-0.24 | $-0.02 | $-0.41 | $-0.42 | $-0.42 | $-0.41 | $-0.30 | |
| EPS (Diluted) | $-0.15 | $-0.15 | $-0.16 | $-0.12 | $-0.13 | $-0.12 | $-1.21 | $-0.11 | $-0.15 | $-0.24 | $-0.02 | $-0.41 | $-0.42 | $-0.42 | $-0.41 | $-0.30 | |
| Shares (Basic) | 142,736,848 | 128,810,050 | -245,025,840 | 122,619,311 | 122,580,967 | 122,390,303 | -136,451,324 | 71,381,731 | 71,291,400 | 71,074,858 | -138,505,385 | 70,807,934 | 70,633,528 | 66,872,778 | -128,882,450 | 66,675,337 | |
| Shares (Diluted) | 142,736,848 | 128,810,050 | -245,025,840 | 122,619,311 | 122,580,967 | 122,390,303 | -136,451,324 | 71,381,731 | 71,291,400 | 71,074,858 | -138,505,385 | 70,807,934 | 70,633,528 | 66,872,778 | -128,882,450 | 66,675,337 | |
| EBITDA | $-24M | $-22M | · | $-17M | $-18M | $-18M | · | $-10M | $-13M | $-19M | · | $-32M | $-32M | $-30M | · | $-21M |
Balance general 24
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $19M | $29M | $20M | $25M | $25M | $30M | $25M | $48M | $23M | $36M | $40M | $39M | $31M | $45M | $45M | $62M | |
| Receivables | · | · | · | · | $194.0K | $250.0K | · | $343.0K | $325.0K | $373.0K | $298.0K | $346.0K | $431.0K | $686.0K | $484.0K | $597.0K | |
| Prepaid Expense | · | · | · | · | $4M | $3M | · | $4M | $6M | $7M | $9M | $20M | $13M | $13M | $13M | $8M | |
| Current Assets | $98M | $110M | $96M | $101M | $104M | $109M | $126M | $132M | $118M | $135M | $129M | $123M | $133M | $184M | $232M | $257M | |
| PP&E (Net) | $664.0K | $750.0K | $761.0K | $811.0K | $868.0K | $942.0K | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | |
| PP&E (Gross) | · | · | · | $6M | $6M | $6M | · | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $5M | $5M | |
| Accum. Depreciation | · | · | · | $5M | $5M | $5M | · | $5M | $5M | $4M | $4M | $5M | $4M | $4M | $4M | $4M | |
| Intangibles | · | · | · | · | · | · | · | · | · | · | · | $7M | $7M | $7M | $7M | $7M | |
| Other Non-current Assets | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | |
| Total Assets | $180M | $199M | $160M | $176M | $189M | $198M | $220M | $182M | $161M | $174M | $197M | $218M | $236M | $230M | $255M | $268M | |
| Accounts Payable | $16M | $15M | $13M | $9M | $9M | $6M | $5M | $8M | $7M | $11M | $9M | $10M | $11M | $8M | $10M | $8M | |
| Accrued Liabilities | $6M | $6M | $9M | $10M | $11M | $9M | $20M | $5M | $6M | $7M | $19M | $15M | $9M | $7M | $9M | $9M | |
| Current Liabilities | $28M | $27M | $29M | $26M | $27M | $22M | $32M | $19M | $16M | $20M | $31M | $27M | $23M | $18M | $22M | $20M | |
| Capital Leases | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | |
| Deferred Tax | · | · | · | · | · | · | · | · | · | · | · | $367.0K | $367.0K | $367.0K | $367.0K | $367.0K | |
| Other Non-current Liabilities | $1M | $1M | $2M | $2M | $2M | $4M | $4M | $2M | $2M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | |
| Total Liabilities | $55M | $55M | $57M | $55M | $57M | $54M | $65M | $52M | $27M | $32M | $40M | $62M | $56M | $53M | $57M | $48M | |
| Common Stock | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | |
| Paid-in Capital | $1.13B | $1.13B | $1.07B | $1.07B | $1.06B | $1.06B | $1.06B | $936M | $933M | $930M | $928M | $927M | $921M | $888M | $881M | $876M | |
| Retained Earnings | $-1.01B | $-988M | $-968M | $-948M | $-933M | $-918M | $-903M | $-806M | $-799M | $-788M | $-771M | $-769M | $-740M | $-710M | $-682M | $-655M | |
| AOCI | $-304.0K | $22.0K | $610.0K | $597.0K | $482.0K | $434.0K | $97.0K | $427.0K | $-463.0K | $-364.0K | $-106.0K | $-1M | $-1M | $-354.0K | $-897.0K | $-1M | |
| Stockholders' Equity | $125M | $144M | $103M | $120M | $132M | $144M | $156M | $130M | $134M | $142M | $157M | $156M | $180M | $177M | $198M | $220M | |
| Liabilities + Equity | $180M | $199M | $160M | $176M | $189M | $198M | $220M | $182M | $161M | $174M | $197M | $218M | $236M | $230M | $255M | $268M | |
| Shares Outstanding | 139,824,273 | 139,652,849 | 120,499,433 | 108,342,592 | 108,328,794 | 108,265,529 | 107,850,124 | 71,417,513 | 71,332,825 | 71,248,017 | 70,894,889 | 70,818,954 | 70,769,702 | 67,206,025 | 66,688,647 | 66,679,641 |
Flujo de Efectivo 11
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $107.0K | $102.0K | $102.0K | $110.0K | $114.0K | $128.0K | $143.0K | $179.0K | $242.0K | $243.0K | $228.0K | $219.0K | $218.0K | $198.0K | $190.0K | $193.0K | |
| Stock-based Comp | $3M | $3M | $3M | $3M | $3M | $4M | $3M | $3M | $3M | $2M | $1M | $6M | $7M | $7M | $5M | $4M | |
| Amort. of Intangibles | · | · | · | · | · | · | · | · | · | · | · | $19.0K | $19.0K | $19.0K | $18.0K | $19.0K | |
| Restructuring | · | · | · | · | · | · | · | $32.0K | $98.0K | $3M | · | · | · | · | · | · | |
| Other Non-cash | · | $-2M | · | · | · | $-2M | · | · | · | $-6M | · | · | · | $-5M | · | · | |
| Operating Cash Flow | $-20M | $-18M | $-13M | $-11M | $-10M | $-13M | $-9M | $22M | $-12M | $-21M | $-7M | $-25M | $-21M | $-26M | $-19M | $-8M | |
| CapEx | $58.0K | $13.0K | $24.0K | $23.0K | $21.0K | $43.0K | $0 | $0 | $-14.0K | $135.0K | $441.0K | $84.0K | $231.0K | $553.0K | $105.0K | $150.0K | |
| Investing Cash Flow | $10M | $-31M | $10M | $14M | $5M | $19M | $-89M | $3M | $-674.0K | $17M | $8M | $33M | $-20M | $26M | $3M | $1M | |
| Financing Cash Flow | $91.0K | $58M | $-3M | $-3M | $-9.0K | $-275.0K | $75M | $22.0K | $-11.0K | $-55.0K | $49.0K | $-87.0K | · | · | $37.0K | $-11.0K | |
| Net Change in Cash | $-9M | $9M | $-5M | $-146.0K | $-5M | $6M | $-23M | $25M | $-13M | $-4M | $838.0K | $8M | $-14M | $-555.0K | $-16M | $-7M | |
| Free Cash Flow | · | $-18M | · | · | · | $-13M | · | · | · | $-21M | · | · | · | $-27M | · | · |
Rentabilidad 6
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1487.9% | -1111.8% | · | -519.8% | -1035.9% | -1242.9% | · | -240.9% | -464.7% | -789.4% | · | -340.2% | -1702.2% | -1183.5% | · | -109.8% | |
| Net Margin | -1320.1% | -993.2% | · | -443.0% | -868.3% | -1036.8% | · | -174.6% | -397.2% | -706.5% | · | -315.2% | -1582.1% | -1113.9% | · | -104.9% | |
| Pretax Margin | · | · | · | -443.0% | -868.3% | -1036.8% | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -1487.9% | -1106.7% | · | -519.8% | -1035.9% | -1234.1% | · | -240.9% | -464.7% | -779.3% | · | -340.2% | -1702.2% | -1175.6% | · | -109.8% | |
| ROA | -11.7% | -10.0% | · | -8.2% | -8.8% | -8.1% | · | -3.8% | -5.5% | -8.4% | · | -12.0% | -11.5% | -12.3% | · | -7.5% | |
| ROE | -16.8% | -13.8% | · | -11.7% | -11.6% | -10.5% | · | -5.3% | -7.0% | -10.6% | · | -15.6% | -14.2% | -15.8% | · | -9.1% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.5 | 4.0 | · | 3.9 | 3.9 | 5.1 | · | 7.0 | 7.5 | 6.7 | · | 4.5 | 5.8 | 10.1 | · | 13.0 | |
| Quick Ratio | 0.7 | 1.0 | · | 1.0 | 1.0 | 1.4 | · | 2.6 | 1.5 | 1.8 | · | 1.4 | 1.4 | 2.5 | · | 3.1 |
Eficiencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.1 | |
| Receivables Turnover | · | · | · | · | 6.8 | 4.7 | · | 12.6 | 7.3 | 4.5 | · | 19.7 | 3.5 | 3.8 | · | 27.0 |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $9M | $9M | · | $11M | $10M | $11M | · | $19M | $16M | $16M | · | $33M | $25M | $25M | · | $24M | |
| Net Income TTM | $-71M | $-65M | · | $-53M | $-49M | $-51M | · | $-65M | $-87M | $-104M | · | $-107M | $-98M | $-87M | · | $-80M | |
| Market Cap | $740M | $524M | · | $206M | $154M | $166M | · | $82M | $78M | $88M | · | $485M | $734M | $544M | · | $1.05B | |
| P/E | -9.6 | -7.2 | · | -4.0 | -2.8 | -2.5 | · | -1.3 | -0.9 | -0.8 | · | -4.4 | -7.2 | -6.0 | · | -12.4 | |
| P/S | 85.0 | 61.4 | · | 18.9 | 14.9 | 15.1 | · | 4.4 | 4.8 | 5.5 | · | 14.8 | 29.4 | 22.2 | · | 44.4 | |
| P/B | 5.9 | 3.6 | · | 1.7 | 1.2 | 1.1 | · | 0.6 | 0.6 | 0.6 | · | 3.1 | 4.1 | 3.1 | · | 4.8 | |
| P / Tangible Book | 5.9 | 3.6 | · | 1.7 | 1.2 | 1.1 | · | 0.6 | 0.6 | 0.6 | · | 3.2 | 4.2 | 3.2 | · | 4.9 | |
| P / Cash Flow | · | -28.9 | · | · | · | -12.7 | · | · | · | -4.2 | · | · | · | -20.6 | · | · | |
| P / FCF | · | -28.8 | · | · | · | -12.6 | · | · | · | -4.2 | · | · | · | -20.2 | · | · | |
| Earnings Yield | -10.4% | -13.9% | · | -25.3% | -35.9% | -40.5% | · | -79.1% | -110.9% | -120.2% | · | -22.6% | -14.0% | -16.6% | · | -8.1% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $8M | $19M | $31M | $30M | $7M |
| Margen Operativo % | -975.9% | -758.2% | -311.6% | -302.0% | -1327.1% |
| Beneficio neto | $-65M | $-132M | $-88M | $-87M | $-91M |
| EPS Diluido | $-0.53 | $-1.71 | $-1.27 | $-1.33 | $-1.60 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 3.4 | 4.0 | 4.2 | 10.6 | 8.9 |
| Ratio Rápido | 0.7 | 0.8 | 1.3 | 2.1 | 1.2 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-47M | $-20M | $-80M | $-68M | $-52M |
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Propietarios institucionales (13F) 160 declarantes · $533.8M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 34 (+3 vs trimestre anterior) | 13 (-1 vs trimestre anterior) | 61 (+22 vs trimestre anterior) | 35 (-4 vs trimestre anterior) | +16.3M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $67 304 808 | 12 723 026 | 12,61% | Acciones |
| BML Capital Management, LLC | $63 347 750 | 11 975 000 | 11,87% | Acciones |
| Deep Track Capital, LP | $49 435 050 | 9 345 000 | 9,26% | Acciones |
| Vivo Capital, LLC | $35 414 630 | 6 694 637 | 6,63% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $30 776 511 | 5 817 866 | 5,77% | Acciones |
| Frazier Life Sciences Management, L.P. | $26 055 228 | 4 925 374 | 4,88% | Acciones |
| Rock Springs Capital Management LP | $22 908 514 | 4 330 532 | 4,29% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $21 535 590 | 4 071 000 | 4,03% | Acciones |
| Decheng Capital LLC | $21 380 783 | 4 041 736 | 4,01% | Acciones |
| STATE STREET CORP | $17 220 749 | 3 255 340 | 3,23% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $14 410 007 | 2 723 241 | 2,70% | Acciones |
| BRAIDWELL LP | $11 333 021 | 2 142 348 | 2,12% | Acciones |
| Balyasny Asset Management L.P. | $10 704 156 | 2 023 470 | 2,01% | Acciones |
| SILVERARC CAPITAL MANAGEMENT, LLC | $10 296 890 | 1 946 482 | 1,93% | Acciones |
| Kalehua Capital Management LLC | $9 693 211 | 1 832 365 | 1,82% | Acciones |
| Jones Hill Capital LP | $9 307 713 | 1 759 492 | 1,74% | Acciones |
| Palo Alto Investors LP | $8 535 045 | 1 613 430 | 1,60% | Acciones |
| Woodline Partners LP | $8 522 476 | 1 611 054 | 1,60% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $7 753 738 | 1 465 735 | 1,45% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $7 174 044 | 1 356 152 | 1,34% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $6 400 297 | 1 209 886 | 1,20% | Acciones |
| MPM BIOIMPACT LLC | $5 514 650 | 1 042 467 | 1,03% | Acciones |
| Aldebaran Capital, LLC | $4 955 307 | 936 731 | 0,93% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $4 798 945 | 907 173 | 0,90% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $4 324 739 | 817 531 | 0,81% | Acciones |
| Three Bridge Wealth Advisors, LLC | $3 781 414 | 714 823 | 0,71% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $2 771 405 | 523 895 | 0,52% | Acciones |
| CITADEL ADVISORS LLC | $2 756 090 | 521 000 | 0,52% | Opción de compra |
| Aisling Capital Management LP | $2 298 267 | 434 455 | 0,43% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $2 263 078 | 427 803 | 0,42% | Acciones |
| ORBIMED ADVISORS LLC | $2 229 735 | 421 500 | 0,42% | Acciones |
| D. E. Shaw & Co., Inc. | $2 192 700 | 414 499 | 0,41% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 182 384 | 412 549 | 0,41% | Acciones |
| Tetragon Partners GP Ltd | $2 116 000 | 400 000 | 0,40% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 830 647 | 346 058 | 0,34% | Acciones |
| GOLDMAN SACHS GROUP INC | $1 546 352 | 292 316 | 0,29% | Acciones |
| FMR LLC | $1 534 645 | 290 103 | 0,29% | Acciones |
| SUPERSTRING CAPITAL MANAGEMENT LP | $1 363 101 | 257 675 | 0,26% | Acciones |
| HighTower Advisors, LLC | $1 150 702 | 217 524 | 0,22% | Acciones |
| Logos Global Management LP | $1 058 000 | 200 000 | 0,20% | Acciones |
| CITADEL ADVISORS LLC | $997 075 | 188 483 | 0,19% | Acciones |
| Verdad Advisers, LP | $927 189 | 175 272 | 0,17% | Acciones |
| KOTLER KEVIN | $920 846 | 305 929 | 0,17% | Acciones |
| Informed Momentum Co LLC | $906 320 | 171 327 | 0,17% | Acciones |
| Assenagon Asset Management S.A. | $817 591 | 154 554 | 0,15% | Acciones |
| Atom Investors LP | $787 443 | 148 855 | 0,15% | Acciones |
| TWO SIGMA ADVISERS, LP | $768 754 | 255 400 | 0,14% | Acciones |
| RHUMBLINE ADVISERS | $757 603 | 143 216 | 0,14% | Acciones |
| ALPS ADVISORS INC | $749 852 | 141 749 | 0,14% | Acciones |
| SEI INVESTMENTS CO | $734 136 | 138 778 | 0,14% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $703 930 | 133 068 | 0,13% | Acciones |
| Vanguard Global Advisers, LLC | $682 706 | 129 056 | 0,13% | Acciones |
| Hudson Bay Capital Management LP | $634 800 | 120 000 | 0,12% | Acciones |
| CenterBook Partners LP | $625 426 | 118 228 | 0,12% | Acciones |
| CITIGROUP INC | $586 904 | 110 946 | 0,11% | Acciones |
| WELLS FARGO & COMPANY/MN | $558 857 | 105 644 | 0,10% | Acciones |
| CITADEL ADVISORS LLC | $550 160 | 104 000 | 0,10% | Opción de venta |
| Verition Fund Management LLC | $518 420 | 98 000 | 0,10% | Acciones |
| BlackRock, Inc. | $478 761 | 90 503 | 0,09% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $448 253 | 84 736 | 0,08% | Acciones |
| Bank of New York Mellon Corp | $430 839 | 81 444 | 0,08% | Acciones |
| STRS OHIO | $430 606 | 81 400 | 0,08% | Acciones |
| BANK OF AMERICA CORP /DE/ | $427 332 | 80 781 | 0,08% | Acciones |
| Voleon Capital Management LP | $408 219 | 77 168 | 0,08% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $403 468 | 76 270 | 0,08% | Acciones |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $396 851 | 75 019 | 0,07% | Acciones |
| MetLife Investment Management, LLC | $368 708 | 69 699 | 0,07% | Acciones |
| BARCLAYS PLC | $349 151 | 66 002 | 0,07% | Acciones |
| JPMORGAN CHASE & CO | $341 772 | 68 082 | 0,06% | Acciones |
| AQR CAPITAL MANAGEMENT LLC | $313 332 | 59 231 | 0,06% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $288 718 | 54 578 | 0,05% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $280 899 | 53 100 | 0,05% | Opción de venta |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $271 906 | 51 400 | 0,05% | Opción de compra |
| MANGROVE PARTNERS IM, LLC | $266 039 | 50 291 | 0,05% | Acciones |
| Invesco Ltd. | $246 905 | 46 674 | 0,05% | Acciones |
| DIVERSIFIED TRUST CO | $240 816 | 45 523 | 0,05% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $213 750 | 57 000 | 0,04% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $205 390 | 38 826 | 0,04% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $187 922 | 35 524 | 0,04% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $171 428 | 32 406 | 0,03% | Acciones |
| PROFUND ADVISORS LLC | $161 271 | 30 486 | 0,03% | Acciones |
| State of Wyoming | $145 152 | 27 439 | 0,03% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $144 417 | 27 300 | 0,03% | Acciones |
| Nuveen, LLC | $139 503 | 26 371 | 0,03% | Acciones |
| INTECH INVESTMENT MANAGEMENT LLC | $130 494 | 24 668 | 0,02% | Acciones |
| VOYA INVESTMENT MANAGEMENT LLC | $122 220 | 23 104 | 0,02% | Acciones |
| China Universal Asset Management Co., Ltd. | $117 586 | 22 228 | 0,02% | Acciones |
| Rafferty Asset Management, LLC | $116 364 | 21 997 | 0,02% | Acciones |
| PRUDENTIAL FINANCIAL INC | $107 228 | 20 270 | 0,02% | Acciones |
| ProShare Advisors LLC | $106 302 | 20 095 | 0,02% | Acciones |
| Verition Fund Management LLC | $105 800 | 20 000 | 0,02% | Opción de compra |
| VANGUARD GROUP INC | $103 661 | 34 439 | 0,02% | Acciones |
| Walleye Capital LLC | $103 557 | 19 576 | 0,02% | Acciones |
| NEUBERGER BERMAN GROUP LLC | $101 991 | 19 280 | 0,02% | Acciones |
| NORTHERN TRUST CORP | $98 463 | 18 613 | 0,02% | Acciones |
| Vontobel Holding Ltd. | $95 220 | 18 000 | 0,02% | Acciones |
| CRA Financial Services, LLC | $94 067 | 17 782 | 0,02% | Acciones |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | $85 021 | 16 072 | 0,02% | Acciones |
| Vanguard Personalized Indexing Management, LLC | $83 005 | 15 691 | 0,02% | Acciones |
| Dynamic Technology Lab Private Ltd | $72 000 | 13 521 | 0,01% | Acciones |
Informantes de la empresa 26 insiders · 13 directivos · 13 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Neal Walker | Interim President and CEO | 1 de marzo de 2024 M | 1 279 445 | 0 | 0 | $0 |
| Douglas J. Manion | Pres and CEO | 1 de enero de 2024 M | 41 813 | 0 | 0 | $0 |
| Kevin Balthaser | Chief Financial Officer | 2 de marzo de 2024 M | 23 983 | 0 | 0 | $0 |
| Frank Ruffo | Chief Financial Officer | 10 de marzo de 2022 S | 201 883 | 0 | 0 | $0 |
| Roland Wilhelm Kolbeck | Chief Scientific Officer | 1 de agosto de 2026 M | 23 990 | 0 | 0 | $0 |
| Joseph Monahan | Chief Scientific Officer | 2 de marzo de 2024 M | 186 783 | 0 | 0 | $0 |
| James Loerop | Chief Business Officer | 1 de febrero de 2024 A | 34 017 | 0 | 0 | $0 |
| Gail Cawkwell | Chief Medical Officer | 1 de julio de 2023 M | 9 593 | 0 | 0 | $0 |
| Kamil Ali-Jackson | Chief Legal Officer | 3 de enero de 2022 M | 160 214 | 0 | 0 | $0 |
| David N. Gordon | Chief Medical Officer | 13 de julio de 2021 S | 147 447 | 0 | 0 | $0 |
| Stuart Shanler | Chief Scientific Officer | 1 de marzo de 2019 A | 272 047 | 0 | 0 | $0 |
| Brett Fair | Chief Commercial Officer | 1 de febrero de 2019 M | 10 582 | 0 | 0 | $0 |
| Christopher Powala | Chief Reg & Develop Officer | 1 de febrero de 2019 M | 141 729 | 0 | 0 | $0 |
| Maxine Gowen | Consejero | 5 de junio de 2026 M | 33 334 | 0 | 0 | $0 |
| Vincent Milano | Consejero | 5 de junio de 2026 M | 28 896 | 0 | 0 | $0 |
| Andrew N Schiff | Consejero | 5 de junio de 2026 M | 25 540 | 0 | 0 | $0 |
| William D. Humphries | Consejero | 4 de junio de 2026 A | 45 105 | 0 | 0 | $0 |
| Christopher P. Molineaux | Consejero | 4 de junio de 2026 A | 69 536 | 0 | 0 | $0 |
| Anand Mehra | Consejero | 4 de junio de 2026 A | 726 403 | 0 | 0 | $0 |
| Andrew Kenneth William Powell | Consejero | 4 de marzo de 2024 P | 28 863 | 0 | 0 | $0 |
| Bryan M. Reasons | Consejero | 2 de junio de 2023 M | 24 072 | 0 | 0 | $0 |
| Stephen A. Tullman | Consejero | 4 de octubre de 2018 P | 177 457 | 0 | 0 | $0 |
| Rick Bierly | Consejero | 15 de junio de 2017 A | — | 0 | 0 | $0 |
| Albert Cha | Consejero | 29 de junio de 2016 A | 4 191 397 | 0 | 0 | $0 |
| Leonard Braden Michael | — | 23 de abril de 2026 S | 13 950 000 | 0 | 1 | $-1 359 000 |
| FMR LLC | — | 21 de agosto de 2017 | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 4 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| M. Arkin (1999) Ltd., Moshe Arkin ×3 presentaciones | 19 de diciembre de 2019 | — | Presentación inicial | — | SEC |
| Vivo Ventures VII, LLC ×6 presentaciones | 14 de febrero de 2019 | — | Presentación inicial | — | SEC |
| Sofinnova Venture Partners VIII, L.P. (“SVP VIII”), Sofinnova Management VIII, L.L.C. (“SM VIII”), Dr. Michael F. Powell (“Powell”), Dr. James I. Healy (“Healy”), Dr. Anand Mehra (“Mehra”) ×3 presentaciones | 14 de febrero de 2018 | — | Presentación inicial | Inversión pasiva | SEC |
| Vivo Ventures VII, LLC FEIN, Vivo Ventures Fund VII, L.P. FEIN, Vivo Ventures VII Affiliates Fund, L.P. FEIN | 20 de octubre de 2015 | — | Presentación inicial | Inversión pasiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 31 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| QQQS · Invesco Exchange-Traded Fund Trust … | 0,64% | 24 606 SH | 8 de agosto de 2026 | Diario |
| SBIO · ALPS ETF Trust | 0,35% | 124 304 NS | 31 de mayo de 2026 | N-PORT |
| IWC · iShares Trust | 0,16% | 403 020 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,09% | 325 402 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,06% | 7 600 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,05% | 804 183 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,04% | 937 472 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,03% | 109 271 SH | 8 de agosto de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 140 543 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,03% | 4 459 NS | 31 de mayo de 2026 | N-PORT |
| IWM · iShares Trust | 0,02% | 3 031 548 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 682 643 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,02% | 112 161 NS | 31 de mayo de 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,02% | 8 224 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,01% | 39 794 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 4 319 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 1 449 139 SH | 8 de agosto de 2026 | Diario |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 14 250 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 324 191 SH | 8 de agosto de 2026 | Diario |
| IWN · iShares Trust | 0,01% | 165 919 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,01% | 3 377 NS | 31 de mayo de 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 3 414 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 92 512 NS | 30 de abril de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 86 NS | 31 de mayo de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 275 717 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 39 408 SH | 8 de agosto de 2026 | Diario |
| DFAU · Dimensional ETF Trust | 0,00% | 26 214 NS | 30 de abril de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 404 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 21 533 NS | 30 de abril de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 4 243 349 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 9 978 SH | 8 de agosto de 2026 | Diario |