AGEN Agenus Inc. - Common Stock

NASDAQ · Biotechnology · Ver en SEC EDGAR ↗
$8,15
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 7, 2026

Acerca de Agenus Inc. - Common Stock Descripción general de la empresa de Wikipedia

Agenus Inc. is a Lexington, Massachusetts-based biotechnology company focused on immunotherapy including immuno-oncology, a field that uses the immune system to control or cure cancer. The company is developing checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly fast-moving field, since early products have produced unprecedented clinical benefits for patients.

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Agenus Inc. is a Lexington, Massachusetts-based biotechnology company focused on immunotherapy including immuno-oncology, a field that uses the immune system to control or cure cancer. The company is developing checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly fast-moving field, since early products have produced unprecedented clinical benefits for patients.

History

Agenus (formerly Antigenics Inc.) was founded in 1994 by Garo H. Armen and Pramod K. Srivastava. The company has pioneered immunotherapies, including heat shock protein-based cancer vaccines, a program that has developed into its Prophage Series of personalized anti-cancer vaccines. Antigenics became a public company in February 2000 on the NASDAQ exchange with the ticker symbol AGEN. In 2000 Agenus acquired Aquila Biopharmaceuticals and a year later it acquired Aronex Pharmaceuticals. In February 2014 the company acquired a European firm, 4-Antibody, along with their portfolio of checkpoint modulators (CPMs) and a platform (Retrocyte Display® technology) to rapidly and efficiently discover new antibodies.

In October 2013, Agenus CEO Garo Armen issued a press release revealing that after an 18-month follow up on the RTS,S Malaria vaccine using QS21-Stimulon®, it was working well enough to support a regulatory filing in 2014. This was the first proof of the efficacy of Agenus's patented "QS-21 Stimulon" adjuvant

In April 2014, Agenus signed a deal with Merck potentially worth $100 million. Under the terms of that deal, Agenus is using its proprietary Retrocyte Display technology to discover antibodies against a pair of undisclosed checkpoint targets for the treatment of cancer. Agenus has advanced two of its own CPM candidates into early drug development and the company is planning to advance several more antibodies in clinical trials.

Today, Agenus is focused on developing a range of immuno-oncology products, including the Prophage vaccines, multiple checkpoint modulators (also known as checkpoint inhibitors or checkpoint antibodies) and its QS21-Stimulon adjuvant. The company's personalized, heat shock protein-based vaccines are in Phase 2 studies. The QS-21 Stimulon adjuvant platform is partnered with GlaxoSmithKline and Janssen. Several of those collaborations involve Phase 3 trials. Altogether, the company and its partners are sponsoring approximately 20 clinical trials of Agenus products.

In August 2023, Agenus announced a strategic restructuring to prioritize its botensilimab and balstilimab (BOT/BAL) clinical programs. The plan included a 25% reduction in its workforce (approximately 85 positions) and the temporary suspension of most preclinical and clinical programs not related to the BOT/BAL combination. The company stated the reorganization was intended to reduce annual operating expenses by approximately $40 million.

In 2025, Agenus sold their CDMO business to Zydus Lifesciences including their two biologics manufacturing sites in Emeryville and Berkeley. In addition, they would partner with Zydus to commercialize their molecules in India.

Key partners and deals

In April 2014, Agenus announced a collaboration and licensing agreement with Merck. The collaboration involved the discovery and development of therapeutic antibodies to two undisclosed Merck checkpoint targets, both thought to be relevant for cancer treatment, in addition to Agenus using its proprietary Retrocyte Display® platform to discover and optimize antibodies against the targets.

In February 2014, Agenus acquired European biotechnology firm 4-Antibody, along with its Retrocyte Display technology and a portfolio of checkpoint modulator antibody candidates .

In March 2012, GlaxoSmithKline acquired two extra rights in the two firms' agreement to use Agenus' QS-21 Stimulon adjuvant. The rights give GSK the first right in negotiation of purchase of Agenus or their assets, the rights expired in 2017 after five years had lapsed.

In June 2025, Agenus entered into a strategic collaboration with Zydus Lifesciences valued at up to $141 million. Under the agreement, Agenus transferred its biologics manufacturing facilities in Emeryville and Berkeley, California, to a new Zydus subsidiary, Zylidac Bio LLC, for an upfront payment of $75 million. The deal also included a $16 million equity investment by Zydus in Agenus common stock and up to $50 million in potential milestone payments. Additionally, Zydus obtained exclusive rights to develop and commercialize the botensilimab and balstilimab (BOT/BAL) combination therapy in India and Sri Lanka, with Agenus eligible for a 5% royalty on net sales. The transaction was formally closed in January 2026.

Product descriptions

Checkpoint modulators (CPMs) interfere with cancers’ ability to “hijack” natural immune defense systems. To protect the body against disease, but without attacking healthy cells, the immune system uses multiple “checkpoint” systems. Some checkpoints stimulate immune responses while others inhibit them. Cancer cells can evolve means to evade checkpoints, and CPMs can reverse that effect, helping the immune system better fight the cancer.

Agenus has programs targeting the checkpoint modulators GITR, OX40, CTLA-4, LAG-3, TIM-3 and PD-1. The company is expanding that portfolio by using a proprietary process to generate fully human therapeutic antibody drug candidates. The platform is a high-throughput approach incorporating IgG format human antibody libraries expressed in mammalian B-lineage cells.

The Prophage series of patient-specific cancer vaccine candidates can also enhance the immune system's response to tumors. Because each cancer is unique, the vaccine is derived from the patient's own tumor sample. To process these samples, Agenus has established a multi-product "good manufacturing practices" facility, which has already helped process over 1,000 tumor samples from across the globe.

The company's QS-21 Stimulon® adjuvant platform strengthens and broadens immune responses to antigens on cancers or foreign invaders’ surfaces. Agenus has multiple partnerships around this product to study its effects with vaccines for diseases including Alzheimer's, melanoma, and malaria. In October 2013, GlaxoSmithKline and Agenus announced positive data from an 18-month follow-up of GSK's RTS,S malaria vaccine with QS21-Stimulon. GSK stated that the treatment was working well enough to support a regulatory filing. RTS,S is the most advanced vaccine for malaria in development.

Agenus is the sole US-manufacturer of a patented and FDA-approved triterpene glycoside extract known as (QS-21, Matrix M), which is a key component in the manufacturing of the Oxford–AstraZeneca COVID-19 as well as the Novavax COVID-19 vaccines. Supplies are tightly controlled, and the US has invoked the US Defence Production Act to preserve vaccine raw materials for its own companies.

Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗

Wikidata ↗

AGEN Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas

Precio
$8.15
Capitalización Bursátil
$288M
P/E (TTM)
BPA (TTM)
$0.00
Ingresos (TTM)
$114M
Rendimiento div.
ROE
1.0%
Deuda/Capital
-0.2
Rango 52S
$3 – $9

AGEN Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista

Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA

Ingresos y Beneficio Neto $114M
10-point trend, +405.9%
2016-12-31 2025-12-31
BPA $0.00
6-point trend, +100.0%
2020-12-31 2025-12-31
Flujo de caja libre $-77M
10-point trend, +16.5%
2016-12-31 2025-12-31
Márgenes -2.7%

Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?

Métrica
Tendencia a 5 años
AGEN
Mediana de Pares
P/S (TTM) (P/V (TTM))
2.5
25.4
P/B (P/C)
-1.1
1.8
EV / EBITDA
-16.3
Price / FCF (Precio / FCF)
-3.7

Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC

Métrica
Tendencia a 5 años
AGEN
Mediana de Pares
Operating Margin (Margen Operativo)
5-point trend, -302.8%
-17.7%
Net Profit Margin (Margen de Beneficio Neto)
5-point trend, +72.2%
-2.7%
-892.4%
ROA
5-point trend, +83.9%
-1.4%
-40.4%
ROE
5-point trend, -97.0%
1.0%
-52.2%
ROIC
3-point trend, +107.6%
8.9%

Salud financiera Deuda, liquidez, solvencia — solidez del balance general

Métrica
Tendencia a 5 años
AGEN
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
5-point trend, -141.9%
-0.2
0.0
Current Ratio (Ratio corriente)
5-point trend, -80.5%
0.4
6.5
Quick Ratio (Ratio Rápido)
5-point trend, -99.2%
0.0

Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años

Métrica
Tendencia a 5 años
AGEN
Mediana de Pares
Revenue YoY (Ingresos interanuales)
5-point trend, -61.4%
10.4%
Revenue CAGR 3Y (Ingresos CAGR 3A)
5-point trend, -61.4%
5.2%
Revenue CAGR 5Y (Ingresos CAGR 5A)
5-point trend, -61.4%
5.3%

Métricas por acción BPA, valor contable por acción, flujo de caja por acción, dividendo por acción

Métrica
Tendencia a 5 años
AGEN
Mediana de Pares
EPS (Diluted) (BPA (Diluido))
5-point trend, +100.0%
$0.00

Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar

Métrica
Tendencia a 5 años
AGEN
Mediana de Pares

AGEN Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista

COMPRA 8 analistas
  • Compra fuerte 2 25,0%
  • Compra 5 62,5%
  • Mantener 1 12,5%
  • Venta 0 0,0%
  • Venta fuerte 0 0,0%

Precio objetivo a 12 meses

2 analistas · 2026-08-16
Objetivo mediano $19.50 +139,3%
Objetivo medio $19.50 +139,3%

Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados

Sorpresa Media
-0.38%
Período EPS Actual EPS est. Sorpresa
30 de junio de 2026 $-0.01 $0.05 -0.06%
31 de marzo de 2026 $0.00 $2.14 -2.1%
31 de diciembre de 2025 $-0.31 $-1.07 0.76%
30 de septiembre de 2025 $1.94 $2.02 -0.08%
30 de junio de 2025 $-1.00 $1.38 -2.4%
31 de marzo de 2025 $-1.03 $-1.69 0.66%
31 de diciembre de 2024 $-2.04 $-2.59 0.55%

Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector

Ticker Capitalización Bursátil P/E Ingresos interanuales Margen Neto ROE Margen Bruto
AGEN $111M 10.4% -2.7% 1.0%
ENTA $256M -3.1 -3.4% -125.4% -103.5%
RCKT
UPB $1.47B -10.2 20.4% -5026.0% -38.3%
IPSC $87M -7.1 1556.8% -8.8% -5.2%
XFOR $364M -2.1 150.0% -1218.5% -83.2%
PALI $375M -7.8 -25.4%
GALT $271M -8.7 25.0%

Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja

Estado de resultados 16
Datos anuales de Estado de resultados para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +1536.6% $114M $103M $156M $98M $296M $88M $150M $37M $43M $23M $25M $7M
Cost of Revenue 7-point trend, +1022000.00 $1M $486.0K $3M $11M $3M $2M · · · · · $0
R&D Expense 12-point trend, +255.0% $79M $156M $235M $187M $179M $143M $168M $125M $116M $95M $70M $22M
SG&A Expense 12-point trend, +156.0% $54M $72M $79M $81M $76M $59M $46M $37M $34M $33M $28M $21M
Operating Income 12-point trend, +53.4% $-20M $-120M $-160M $-179M $26M $-117M $-70M $-124M $-104M $-107M $-81M $-43M
Interest Expense · · · · · · · · · · · $1M
Interest Income 4-point trend, -84.7% $345.0K $3M $6M $2M · · · · · · · ·
Other Non-op 12-point trend, +3351.7% $72M $6M $37.0K $11M $5M $-2M $28.0K $-2M $2M $-2M $-6M $2M
Pretax Income 7-point trend, +92.7% $-3M $-232M $-257M · · · · · $-121M $-127M $-93M $-42M
Income Tax 12-point trend, +0.00 $0 $0 $0 $0 $0 $0 $0 $0 $0 $0 $-5M $0
Net Income 11-point trend, +92.7% $-3M $-232M $-257M $-231M $-29M $-183M $-112M · $-121M $-127M $-88M $-42M
EPS (Basic) 6-point trend, +100.0% $0.00 $-10.59 $-13.75 $-15.64 $-0.11 $-1.05 · · · · · ·
EPS (Diluted) 6-point trend, +100.0% $0.00 $-10.59 $-13.75 $-15.64 $-0.11 $-1.05 · · · · · ·
Shares (Basic) 6-point trend, +17136.7% 29,734,000 21,473,000 17,894,000 14,087,000 228,919 172,504 · · · · · ·
Shares (Diluted) 6-point trend, +17136.7% 29,734,000 21,473,000 17,894,000 14,087,000 228,919 172,504 · · · · · ·
EBITDA 11-point trend, +75.0% $-20M $-120M $-160M $-179M $26M $-117M $-70M $-124M $-104M $-107M $-81M ·
Balance general 29
Datos anuales de Balance general para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, -88.3% $3M $40M $76M $179M $292M $100M $62M $53M $60M $71M $137M $26M
Short-term Investments 5-point trend, +1.2% · · · $15M $15M · · · · $5M $35M $15M
Receivables 12-point trend, +295.5% $2M $407.0K $26M $3M $2M $1M $16M $938.0K $1M $11M $10M $463.0K
Inventory 6-point trend, -100.0% · · · · · · $0 $55.0K $79.5K $88.2K $88.2K $95.7K
Prepaid Expense 12-point trend, -37.1% $785.0K $2M $8M $14M $20M $11M $7M $19M $11M $3M $2M $1M
Other Current Assets 12-point trend, +70.2% $1M $2M $2M $3M $3M $2M $1M $1M $1M $838.5K $582.3K $640.0K
Current Assets 12-point trend, +212.7% $133M $46M $112M $213M $332M $114M $87M $75M $74M $91M $184M $43M
PP&E (Net) 12-point trend, +158.0% $15M $120M $133M $133M $60M $27M $26M $25M $26M $26M $15M $6M
PP&E (Gross) 12-point trend, +83.1% $63M $193M $195M $187M $111M $74M $69M $63M $60M $57M $45M $34M
Accum. Depreciation 12-point trend, +67.3% $47M $73M $62M $54M $51M $47M $43M $38M $34M $31M $29M $28M
Goodwill 12-point trend, +34.8% $24M $24M $25M $25M $25M $25M $23M $23M $23M $22M $23M $18M
Intangibles 12-point trend, -55.2% $3M $3M $4M $6M $8M $11M $11M $12M $14M $16M $19M $7M
Other Non-current Assets 12-point trend, +171.8% $3M $6M $9M $4M $10M $4M $1M $1M $1M $1M $1M $1M
Total Assets 12-point trend, +204.3% $227M $226M $314M $414M $466M $215M $155M $136M $138M $157M $242M $75M
Accounts Payable 12-point trend, +4750.4% $83M $61M $61M $41M $30M $17M $14M $14M $8M $5M $4M $2M
Accrued Liabilities 12-point trend, +522.1% $34M $35M $45M $38M $42M $29M $31M $25M $22M $28M $14M $6M
Current Liabilities 12-point trend, +3405.0% $323M $221M $256M $189M $157M $130M $122M $68M $56M $41M $29M $9M
Capital Leases 7-point trend, +26.0% $10M $55M $63M $63M $42M $34M $8M · · · · ·
Other Non-current Liabilities 12-point trend, -90.8% $259.0K $738.0K $5M $15M $2M $2M $4M $3M $3M $5M $8M $3M
Long-term Debt 12-point trend, +641.0% $45M $33M $13M $13M $14M $20M $14M $13M $163M $131M $114M $6M
Total Debt 11-point trend, -61.0% $45M $33M $13M $13M $14M $20M $14M $13M $163M $131M $114M ·
Common Stock 12-point trend, -43.7% $353.0K $236.0K $197.0K $3M $3M $2M $1M $1M $1M $877.9K $863.9K $627.2K
Paid-in Capital 12-point trend, +167.1% $1.91B $1.86B $1.80B $1.64B $1.52B $1.26B $1.06B $1.01B $952M $867M $851M $716M
Retained Earnings 12-point trend, -215.7% $-2.18B $-2.18B $-1.96B $-1.71B $-1.49B $-1.47B $-1.28B $-1.18B $-1.03B $-905M $-779M $-691M
Treasury Stock · · · · · · · · · · · $0
AOCI 12-point trend, +77.7% $-439.0K $-1M $-955.0K $915.0K $1M $3M $-1M $-2M $-2M $-2M $-2M $-2M
Stockholders' Equity 12-point trend, -1277.8% $-271M $-326M $-160M $-61M $34M $-204M $-225M $-172M $-76M $-39M $71M $23M
Liabilities + Equity 12-point trend, +204.3% $227M $226M $314M $414M $466M $215M $155M $136M $138M $157M $242M $75M
Shares Outstanding 3-point trend, +79.1% 35,320,397 23,634,670 19,718,662 · · · · · · · · ·
Flujo de Efectivo 12
Datos anuales de Flujo de Efectivo para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
D&A 12-point trend, +531.3% $10M $13M $14M $7M $7M $7M $7M $6M $6M $5M $2M $2M
Stock-based Comp 12-point trend, +194.7% $14M $17M $23M $18M $20M $10M $10M $8M $12M $13M $7M $5M
Deferred Tax 4-point trend, +100.0% $0 $0 $0 · · · · · · · $-5M ·
Amort. of Intangibles 12-point trend, -35.1% $300.0K $500.0K $2M $2M $2M $2M $2M $2M $2M $2M $2M $462.0K
Operating Cash Flow 12-point trend, -101.9% $-77M $-158M $-224M $-175M $10M $-139M $-19M $-131M $-94M $-80M $-47M $-38M
CapEx 12-point trend, -99.8% $6.0K $576.0K $10M $53M $34M $3M $5M $4M $3M $13M $4M $3M
Investing Cash Flow 11-point trend, +107.1% $1M $27.0K $3M $-34M $-43M $-4M $-5M $-4M $2M $18M · $-17M
Debt Issued 3-point trend, -94.3% · · · · · $6M · · $15M · $109M ·
Net Debt Issued 4-point trend, -102.3% $-2M · · · · $6M · · $15M · $109M ·
Financing Cash Flow 11-point trend, -30.7% $37M $123M $120M $96M $225M $184M $31M $128M $81M $-2M · $53M
Net Change in Cash 12-point trend, -2303.8% $-39M $-36M $-102M $-113M $192M $41M $9M $-7M $-11M $-65M $111M $-2M
Free Cash Flow 11-point trend, -52.1% $-77M $-159M $-234M $-228M $-24M $-143M $-23M $-135M $-97M $-92M $-51M ·
Rentabilidad 7
Datos anuales de Rentabilidad para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +94.6% -17.7% -116.4% -102.1% -183.0% 8.7% -133.0% -46.7% -336.6% -242.1% -476.1% -325.2% ·
Net Margin 8-point trend, +99.2% -2.7% -224.5% -164.7% -235.3% -9.7% · · · -281.5% -562.6% -354.1% ·
Pretax Margin 4-point trend, +99.3% -2.7% · · · · · · · -281.5% -562.6% -375.8% ·
EBITDA Margin 11-point trend, +94.6% -17.7% -116.4% -102.1% -183.0% 8.7% -133.0% -46.7% -336.6% -242.1% -476.1% -325.2% ·
ROA 8-point trend, +97.5% -1.4% -86.0% -70.8% -52.4% -8.4% · · · -81.7% -63.6% -55.5% ·
ROE 8-point trend, +100.5% 1.0% 95.5% 232.3% 1718.9% 34.0% · · · 210.0% -803.7% -187.5% ·
ROIC 4-point trend, +121.7% 8.9% · · · · · · · -119.0% -117.4% -41.1% ·
Liquidez y Solvencia 4
Datos anuales de Liquidez y Solvencia para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -93.5% 0.4 0.2 0.4 1.1 2.1 0.9 0.7 1.1 1.3 2.2 6.4 ·
Quick Ratio 11-point trend, -99.8% 0.0 0.2 0.4 1.0 2.0 0.8 0.6 0.8 1.1 2.1 6.3 ·
Debt / Equity 11-point trend, -110.2% -0.2 -0.1 -0.1 -0.2 0.4 -0.1 -0.1 -0.1 -2.2 -3.3 1.6 ·
LT Debt / Equity 11-point trend, -100.0% 0.0 -0.1 -0.1 -0.2 0.4 -0.1 -0.1 -0.1 -1.9 -3.3 1.6 ·
Eficiencia 2
Datos anuales de Eficiencia para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +221.7% 0.5 0.4 0.4 0.2 0.9 0.5 1.0 0.3 0.3 0.1 0.2 ·
Receivables Turnover 11-point trend, +2010.3% 102.1 7.9 10.9 46.0 221.1 10.1 17.4 35.5 6.9 2.1 4.8 ·
Por Acción 5
Datos anuales de Por Acción para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Book Value / Share $-7.68 · · · · · · · · · · ·
Revenue / Share 4-point trend, -98.9% $3.84 $4.82 $436.77 $347.92 · · · · · · · ·
Cash Flow / Share 4-point trend, +99.6% $-2.60 $-7.37 $-626.46 $-622.46 · · · · · · · ·
Cash / Share $0.08 · · · · · · · · · · ·
EPS (TTM) 11-point trend, +100.0% $0.00 $-10.59 $-13.75 $-15.64 $-0.11 $-1.05 $-0.81 · $-1.13 $-1.13 $-1.13 $-1.13
Tasas de Crecimiento 3
Datos anuales de Tasas de Crecimiento para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -95.6% 10.4% -33.8% 59.5% -66.8% 235.3% · · · · · · ·
Revenue CAGR 3Y 3-point trend, -75.2% 5.2% -29.5% 21.0% · · · · · · · · ·
Revenue CAGR 5Y 5.3% · · · · · · · · · · ·
Valoración (TTM) 13
Datos anuales de Valoración (TTM) para AGEN
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +1536.6% $114M $103M $156M $98M $296M $88M $150M $37M $43M $23M $25M $7M
Net Income TTM 12-point trend, +92.7% $-3M $-232M $-257M $-231M $-29M $-183M $-112M $-162M $-121M $-127M $-88M $-42M
Market Cap $111M · · · · · · · · · · ·
Enterprise Value $153M · · · · · · · · · · ·
P/E 10-point trend, +99.6% · -0.3 -1.2 -3.0 -574.5 -59.4 -98.6 · -56.6 -71.6 -78.9 -69.0
P/S 1.0 · · · · · · · · · · ·
P/B -0.4 · · · · · · · · · · ·
P / Cash Flow -1.4 · · · · · · · · · · ·
P / FCF -1.4 · · · · · · · · · · ·
EV / EBITDA -7.6 · · · · · · · · · · ·
EV / FCF -2.0 · · · · · · · · · · ·
EV / Revenue 1.3 · · · · · · · · · · ·
Earnings Yield 11-point trend, +100.0% 0.00% -386.5% -82.8% -33.2% -0.17% -1.7% -1.0% · -1.8% -1.4% -1.3% -1.5%

Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años

Estado de resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ingresos $114M$103M$156M$98M$296M
Margen Operativo % -17.7%-116.4%-102.1%-183.0%8.7%
Beneficio neto $-3M$-232M$-257M$-231M$-29M
EPS Diluido $0.00$-10.59$-13.75$-15.64$-0.11
Balance general
2025-12-312024-12-312023-12-312022-12-312021-12-31
Deuda / Patrimonio -0.2-0.1-0.1-0.20.4
Ratio corriente 0.40.20.41.12.1
Ratio Rápido 0.00.20.41.02.0
Flujo de Efectivo
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flujo de caja libre $-77M$-159M$-234M$-228M$-24M

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Propietarios institucionales (13F) 117 declarantes · $30.7M total · A fecha de 30 de junio de 2026

Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.

Actividad institucional — Q2 2026 vs trimestre anterior
Nuevas posiciones Posiciones cerradas Aumentado Disminuido Cambio neto de acciones
37 (+23 vs trimestre anterior) 14 (-3 vs trimestre anterior) 27 (+7 vs trimestre anterior) 22 (-6 vs trimestre anterior) +2.4M

Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.

Institución Valor Acciones % de 13F rastreadas Tipo
VANGUARD CAPITAL MANAGEMENT LLC $5 128 854 1 676 096 16,71% Acciones
VANGUARD PORTFOLIO MANAGEMENT LLC $4 368 416 1 427 587 14,23% Acciones
Siren, L.L.C. $3 256 605 1 064 250 10,61% Acciones
GEODE CAPITAL MANAGEMENT, LLC $2 731 786 892 458 8,90% Acciones
MACKENZIE FINANCIAL CORP $2 185 376 714 175 7,12% Acciones
GLOBEFLEX CAPITAL L P $1 280 858 418 581 4,17% Acciones
STATE STREET CORP $1 261 892 412 383 4,11% Acciones
Man Group plc $1 041 701 340 425 3,39% Acciones
GOLDMAN SACHS GROUP INC $1 017 753 332 599 3,32% Acciones
Connor, Clark & Lunn Investment Management Ltd. $948 707 310 035 3,09% Acciones
VANGUARD FIDUCIARY TRUST CO $831 139 271 614 2,71% Acciones
RENAISSANCE TECHNOLOGIES LLC $698 739 228 346 2,28% Acciones
PANAGORA ASSET MANAGEMENT INC $549 542 179 589 1,79% Acciones
Susquehanna Portfolio Strategies, LLC $485 735 158 737 1,58% Acciones
Cubist Systematic Strategies, LLC $393 512 102 211 1,28% Acciones
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $304 140 99 392 0,99% Acciones
TWO SIGMA INVESTMENTS, LP $301 976 98 685 0,98% Acciones
STRS OHIO $235 314 76 900 0,77% Acciones
CANADA PENSION PLAN INVESTMENT BOARD $205 326 67 100 0,67% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $128 569 42 016 0,42% Acciones
Avestar Capital, LLC $125 460 41 000 0,41% Acciones
BlackRock, Inc. $124 756 40 770 0,41% Acciones
DEUTSCHE BANK AG\ $119 046 38 904 0,39% Acciones
Bank of New York Mellon Corp $115 998 37 908 0,38% Acciones
MARSHALL WACE, LLP $109 602 35 818 0,36% Acciones
TWO SIGMA ADVISERS, LP $107 529 34 245 0,35% Acciones
Claro Advisors Inc. $102 051 33 350 0,33% Acciones
XTX Topco Ltd $96 849 31 650 0,32% Acciones
CITADEL ADVISORS LLC $90 270 29 500 0,29% Opción de compra
RHUMBLINE ADVISERS $90 226 29 488 0,29% Acciones
CAPTRUST FINANCIAL ADVISORS $88 654 28 972 0,29% Acciones
BANK OF AMERICA CORP /DE/ $87 354 28 547 0,28% Acciones
Engineers Gate Manager LP $85 092 27 808 0,28% Acciones
CITIGROUP INC $77 733 25 403 0,25% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $77 418 25 300 0,25% Opción de compra
LPL Financial LLC $73 948 24 166 0,24% Acciones
Key Client Fiduciary Advisors, LLC $73 823 24 125 0,24% Acciones
OSAIC HOLDINGS, INC. $71 774 23 456 0,23% Acciones
BNP PARIBAS FINANCIAL MARKETS $67 002 21 896 0,22% Acciones
WOLVERINE TRADING, LLC $63 282 15 900 0,21% Opción de compra
CITADEL ADVISORS LLC $62 730 20 500 0,20% Opción de venta
PRELUDE CAPITAL MANAGEMENT, LLC $60 469 19 761 0,20% Acciones
PRUDENTIAL FINANCIAL INC $59 395 19 410 0,19% Acciones
Vanguard Personalized Indexing Management, LLC $58 749 19 199 0,19% Acciones
NEW YORK STATE COMMON RETIREMENT FUND $57 834 18 900 0,19% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $56 916 18 600 0,19% Opción de venta
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $56 142 18 347 0,18% Acciones
UBS Group AG $52 825 17 263 0,17% Acciones
VANGUARD GROUP INC $49 945 15 906 0,16% Acciones
Vanguard Global Advisers, LLC $48 672 15 906 0,16% Acciones
Invesco Ltd. $48 620 15 889 0,16% Acciones
SHERBROOKE PARK ADVISERS LLC $48 325 15 390 0,16% Acciones
DIVERSIFIED TRUST CO $47 677 15 581 0,16% Acciones
BANK OF MONTREAL /CAN/ $47 207 15 427 0,15% Acciones
Police & Firemen's Retirement System of New Jersey $46 947 15 342 0,15% Acciones
ALLIANCEBERNSTEIN L.P. $41 349 12 380 0,13% Acciones
R Squared Ltd $41 068 13 421 0,13% Acciones
FMR LLC $40 582 13 262 0,13% Acciones
Post Resch Tallon Group Inc. $39 015 12 750 0,13% Acciones
StoneX Group Inc. $36 849 10 728 0,12% Acciones
Abel Hall, LLC $35 986 11 760 0,12% Acciones
RAYMOND JAMES FINANCIAL INC $35 707 11 669 0,12% Acciones
Graham Capital Management, L.P. $35 052 11 455 0,11% Acciones
HSBC HOLDINGS PLC $34 757 11 176 0,11% Acciones
MORGAN STANLEY $34 070 11 134 0,11% Acciones
Values First Advisors, Inc. $33 612 10 984 0,11% Acciones
ZACKS INVESTMENT MANAGEMENT $32 285 10 550 0,11% Acciones
JANE STREET GROUP, LLC $31 824 10 400 0,10% Opción de compra
Point72 Asia (Singapore) Pte. Ltd. $31 366 8 147 0,10% Acciones
EP Wealth Advisors, LLC $30 600 10 000 0,10% Acciones
NORTHERN TRUST CORP $18 902 6 177 0,06% Acciones
BARCLAYS PLC $17 950 5 866 0,06% Acciones
Legal & General Group Plc $11 824 3 864 0,04% Acciones
Ameritas Investment Partners, Inc. $11 065 3 616 0,04% Acciones
FEDERATED HERMES, INC. $10 343 3 380 0,03% Acciones
Pinnacle Wealth Planning Services, Inc. $10 321 3 373 0,03% Acciones
Russell Investments Group, Ltd. $9 733 3 181 0,03% Acciones
Tower Research Capital LLC (TRC) $7 072 2 311 0,02% Acciones
CoreCap Advisors, LLC $6 120 2 000 0,02% Acciones
Atlantic Union Bankshares Corp $5 355 1 750 0,02% Acciones
Caitong International Asset Management Co., Ltd $4 997 1 633 0,02% Acciones
ROYAL BANK OF CANADA $4 000 1 360 0,01% Acciones
Jump Financial, LLC $3 614 1 181 0,01% Acciones
CHILTON CAPITAL MANAGEMENT LLC $3 238 1 058 0,01% Acciones
CWM, LLC $2 739 820 0,01% Acciones
NISA INVESTMENT ADVISORS, LLC $2 592 847 0,01% Acciones
Sterling Capital Management LLC $2 157 705 0,01% Acciones
HUNTINGTON NATIONAL BANK $2 032 664 0,01% Acciones
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO $1 937 633 0,01% Acciones
Physician Wealth Advisors, Inc. $1 901 621 0,01% Acciones
Game Plan Financial Advisors, LLC $1 790 585 0,01% Acciones
Optiver Holding B.V. $1 756 574 0,01% Acciones
GROUP ONE TRADING LLC $1 717 561 0,01% Acciones
JPMORGAN CHASE & CO $1 203 382 0,00% Acciones
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $952 285 0,00% Acciones
Rialto Wealth Management, LLC $934 305 0,00% Acciones
WELLS FARGO & COMPANY/MN $704 230 0,00% Acciones
Bare Financial Services, Inc $529 173 0,00% Acciones
Bogart Wealth, LLC $523 171 0,00% Acciones
Sandy Spring Bank $377 250 0,00% Acciones

Informantes de la empresa 46 insiders · 7 directivos · 4 consejeros

Insider Rol Última actividad Acciones en propiedad Compras 12m Ventas 12m Neto 12m
Jeff D Clark Chief Financial Officer 18 de febrero de 2004 A 0 0 $0
Austin Charette Principal Accounting Officer 24 de abril de 2026 A 0 0 $0
Christine M Klaskin PFO & PAO 18 de junio de 2025 A 23 478 0 0 $0
Evan Kearns Vice President and General Counsel 24 de diciembre de 2019 A 0 0 $0
Christian Cortis Chief Strategy Officer & Head of Finance 19 de junio de 2019 A 0 0 $0
Alex Duncan Chief Technology Officer 19 de junio de 2019 A 21 026 0 0 $0
Neal Gordon SrVP, Manufacturing Operations 18 de febrero de 2004 A 0 0 $0
Ulf Wiinberg Consejero 1 de octubre de 2024 A 124 063 0 0 $0
Allison M Jeynes-Ellis Consejero 5 de febrero de 2024 A 66 176 0 0 $0
Wadih Jordan Consejero 3 de octubre de 2022 A 0 0 $0
Paul N Clark Consejero 27 de agosto de 2020 A 0 0 $0
AGENUS INC Propietario del 10% 16 de octubre de 2023 P 21 772 863 0 0 $0
INCYTE CORP Propietario del 10% 17 de junio de 2020 S 16 972 968 0 0 $0
Brad M Kelley Propietario del 10% 24 de septiembre de 2003 P 5 546 740 0 0 $0
Garo H Armen 10 de agosto de 2026 A 371 108 0 0 $0
Steven J O'Day 5 de agosto de 2026 A 57 116 0 0 $0
Susan B Hirsch 5 de agosto de 2026 A 108 725 0 0 $0
Jennifer Buell 5 de agosto de 2026 A 19 738 0 0 $0
Brian Corvese 5 de agosto de 2026 A 92 085 0 0 $0
Timothy Wright 5 de agosto de 2026 A 50 391 0 0 $0
Thomas L Harrison 5 de agosto de 2026 A 47 545 0 0 $0
Adam Krauss 15 de junio de 2021 A 0 0 $0
Shalini Sharp 21 de junio de 2018 A 104 270 0 0 $0
Ozer Baysal 20 de junio de 2018 A 58 790 0 0 $0
Karen Valentine 20 de junio de 2018 A 101 521 0 0 $0
Jean-Marie Cuillerot 31 de marzo de 2017 A 0 0 $0
Robert Benjamin Stein 31 de marzo de 2017 A 20 986 0 0 $0
Shahzad Malik 15 de junio de 2016 A 1 587 302 0 0 $0
Charles Evan Ballantyne 14 de junio de 2016 A 24 795 0 0 $0
Tom Dechaene 4 de enero de 2016 A 0 0 $0
Kerry Wentworth 26 de febrero de 2014 S 57 410 0 0 $0
John Hatsopoulos 3 de octubre de 2011 A 65 000 0 0 $0
ROTHWELL TIMOTHY G 3 de octubre de 2011 J 7 389 0 0 $0
Hyam Levitsky 1 de julio de 2011 A 15 376 0 0 $0
Peter Thornton 5 de junio de 2008 A 5 000 0 0 $0
Eisen Margaret 5 de junio de 2008 A 20 000 0 0 $0
AFEYAN NOUBAR 2 de abril de 2007 A 0 0 0 $0
ATLEE FRANK V III 2 de abril de 2007 A 0 0 0 $0
Pramod Srivastava 9 de febrero de 2007 S 1 610 0 0 $0
Roman Chicz 5 de enero de 2007 A 0 0 $0
Mark Kessel 2 de octubre de 2006 A 0 0 $0
Bruce Leicher 15 de septiembre de 2006 A 0 0 $0
Alastair Jj Wood 15 de junio de 2006 A 0 0 $0
Gamil De Chadarevian 28 de febrero de 2006 M 88 610 0 0 $0
Renu Gupta 24 de febrero de 2006 A 0 0 $0
Russell Herndon 8 de diciembre de 2004 A 0 0 $0

Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto

Activistas y propietarios del %+ 5 5 tenencias

Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.

Declarante Presentado Participación Estado Propósito Presentación
ZYNEXT VENTURES USA LLC, ZYNEXT VENTURES PTE LTD, ZYDUS LIFESCIENCES LTD 23 de enero de 2026 5,90% Presentación inicial SEC
Agenus Inc. (“Agenus”) ×3 presentaciones 26 de mayo de 2023 Presentación inicial Inversión pasiva SEC
Garo H. Armen 22 de enero de 2008 Presentación inicial Inversión pasiva SEC
Brad M. Kelley 2) ×4 presentaciones 27 de febrero de 2003 Presentación inicial SEC
Persona informante no revelada 1 de mayo de 2001 Presentación inicial M&A / venta SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Propiedad de ETFs Mantenido por 11 ETFs

El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.

Fondo Ponderación Unidades A fecha de Fuente
VXF · VANGUARD INDEX FUNDS 15 de julio de 2026 Diario
VTI · VANGUARD INDEX FUNDS 15 de julio de 2026 Diario
VTWO · VANGUARD SCOTTSDALE FUNDS 15 de julio de 2026 Diario
VTWV · VANGUARD SCOTTSDALE FUNDS 15 de julio de 2026 Diario
VTWG · VANGUARD SCOTTSDALE FUNDS 15 de julio de 2026 Diario
VTHR · VANGUARD SCOTTSDALE FUNDS 15 de julio de 2026 Diario
IWN · iShares Trust 17 de agosto de 2026 Diario
IWO · iShares Trust 18 de agosto de 2026 Diario
IWM · iShares Trust 18 de agosto de 2026 Diario
IWC · iShares Trust 18 de agosto de 2026 Diario
QQQS · Invesco Exchange-Traded Fund Trust … 5 de agosto de 2026 Diario