APGE Apogee Therapeutics, Inc. - Common Stock
$134,58
Precio · Ago 18, 2026
Fundamentales a fecha de Ago 10, 2026
Rango 52S
$35–$135
100% of range
Calificación del Analista
HOLD
21 analysts
Precio Objetivo
$135
+0% upside
P/E (TTM)
-31.9
ROE
—
Margen de Beneficio Neto
—
APGE Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$134.58
Capitalización Bursátil
$9.21B
P/E (TTM)
-31.9
BPA (TTM)
$-4.22
Ingresos (TTM)
—
Rendimiento div.
—
ROE
—
Deuda/Capital
—
Rango 52S
$35 – $135
APGE Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-4.22
2022-12-31
→
2025-12-31
Flujo de caja libre
$-233M
2023-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
APGE
Mediana de Pares
P/E (TTM)
-31.9
28.5
Price / FCF (Precio / FCF)
-39.6
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
APGE
Mediana de Pares
ROA
-30.3%
-28.4%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
APGE
Mediana de Pares
Current Ratio (Ratio corriente)
26.6
5.0
Quick Ratio (Ratio Rápido)
26.2
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
APGE
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
APGE
Mediana de Pares
APGE Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
MANTENER
21 analistas
- Compra fuerte 3 14,3%
- Compra 4 19,0%
- Mantener 14 66,7%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
11 analistas · 2026-08-14
Mediana
$135.00
Ahora
$134.58
Mín
$133.00
Máx
$135.11
Objetivo mediano
$135.00
+0,3%
Objetivo medio
$134.85
+0,2%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.08%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-1.14 | $-1.09 | -0.05% |
| 31 de marzo de 2026 | $-1.06 | $-1.12 | 0.06% |
| 31 de diciembre de 2025 | $-1.03 | $-1.08 | 0.05% |
| 30 de septiembre de 2025 | $-1.11 | $-1.21 | 0.10% |
| 30 de junio de 2025 | $-1.13 | $-1.10 | -0.03% |
| 31 de marzo de 2025 | $-0.95 | $-1.27 | 0.32% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| APGE | $5.16B | -17.9 | — | — | — | — |
| MDGL | $13.30B | -45.3 | 432.1% | -30.1% | -44.4% | — |
| HALO | $7.93B | 26.3 | 37.5% | 22.7% | 166.1% | — |
| PRAX | $7.43B | -21.9 | 249.5% | — | -47.3% | — |
| CYTK | $7.81B | -9.7 | 376.6% | -891.6% | 152.7% | — |
| PTGX | $5.47B | -42.6 | -89.4% | -282.8% | -20.3% | — |
| KRYS | $7.20B | 36.0 | 33.9% | 52.6% | 18.1% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
| SMMT | $13.56B | -12.1 | — | — | -235.1% | — |
| IONS | $12.92B | -33.2 | — | — | -68.1% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| R&D Expense | $215M | $168M | $68M | $28M | |
| SG&A Expense | $71M | $49M | $25M | $3M | |
| Operating Expenses | $286M | $217M | $93M | $31M | |
| Operating Income | $-286M | $-217M | $-93M | $-31M | |
| Interest Income | $30M | $35M | $9M | $92.0K | |
| Other Non-op | $30M | $35M | $9M | $-9M | |
| Pretax Income | $-256M | $-182M | $-84M | · | |
| Income Tax | $278.0K | $18.0K | $0 | · | |
| Net Income | $-256M | $-182M | $-84M | $-40M | |
| EPS (Basic) | $-4.22 | $-3.30 | $-3.36 | $-16.16 | |
| EPS (Diluted) | $-4.22 | $-3.30 | $-3.36 | $-16.16 | |
| Shares (Basic) | 60,690,820 | 55,193,971 | 25,005,774 | 2,462,236 | |
| Shares (Diluted) | 60,690,820 | 55,193,971 | 25,005,774 | 2,462,236 | |
| EBITDA | $-286M | $-217M | $-93M | · |
Balance general 20
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $132M | $142M | $118M | $152M | |
| Short-term Investments | $599M | $379M | $277M | · | |
| Prepaid Expense | $11M | $9M | $3M | $165.0K | |
| Other Current Assets | $605.0K | $2M | $1M | $57.0K | |
| Current Assets | $741M | $530M | $398M | $152M | |
| PP&E (Net) | $6M | $2M | $377.0K | · | |
| Accum. Depreciation | $2M | $189.0K | · | · | |
| Other Non-current Assets | $9M | $498.0K | $401.0K | · | |
| Total Assets | $937M | $754M | $401M | $152M | |
| Accounts Payable | $1M | $1M | $2M | $418.0K | |
| Accrued Liabilities | $23M | $24M | $17M | $10M | |
| Current Liabilities | $28M | $29M | $21M | $10M | |
| Capital Leases | $5M | $9M | $933.0K | · | |
| Total Liabilities | $33M | $37M | $21M | $10M | |
| Common Stock | $1.0K | $1.0K | · | · | |
| Paid-in Capital | $1.46B | $1.02B | $503M | · | |
| Retained Earnings | $-562M | $-306M | $-124M | $-40M | |
| AOCI | $1M | $915.0K | $329.0K | · | |
| Liabilities + Equity | $937M | $754M | $401M | $152M | |
| Shares Outstanding | 68,401,349 | 58,062,898 | 48,338,769 | 0 |
Flujo de Efectivo 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $46M | $23M | $6M | $2M | |
| Operating Cash Flow | $-227M | $-171M | $-75M | $-16M | |
| CapEx | $5M | $1M | $167.0K | · | |
| Investing Cash Flow | $-180M | $-300M | $-274M | · | |
| Stock Issued | · | $450M | $315M | · | |
| Net Stock Activity | · | $450M | $315M | · | |
| Financing Cash Flow | $396M | $495M | $315M | $168M | |
| Net Change in Cash | $-11M | $23M | $-33M | $152M | |
| Taxes Paid | · | $360.0K | · | · | |
| Free Cash Flow | $-233M | $-172M | $-75M | · |
Rentabilidad 1
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| ROA | -30.3% | -31.5% | -30.3% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 26.6 | 18.5 | 19.4 | · | |
| Quick Ratio | 26.2 | 18.2 | 19.2 | · |
Valoración (TTM) 6
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Net Income TTM | $-256M | $-182M | $-84M | · | |
| Market Cap | $5.16B | $2.63B | $1.35B | · | |
| P/E | -17.9 | -13.7 | -8.3 | · | |
| P / Cash Flow | -22.7 | -15.4 | -18.1 | · | |
| P / FCF | -22.2 | -15.3 | -18.0 | · | |
| Earnings Yield | -5.6% | -7.3% | -12.0% | · |
Estado de resultados 14
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $67M | $61M | $58M | $54M | $56M | $46M | $60M | $46M | $33M | $29M | $17M | $14M | $8M | |
| SG&A Expense | $24M | $22M | $20M | $17M | $17M | $17M | $16M | $13M | $11M | $9M | $7M | $5M | $4M | |
| Operating Expenses | $96M | $83M | $78M | $71M | $73M | $63M | $76M | $59M | $44M | $38M | $24M | $19M | $13M | |
| Operating Income | $-96M | $-83M | $-78M | $-71M | $-73M | $-63M | $-76M | $-59M | $-44M | $-38M | $-24M | $-19M | $-13M | |
| Interest Income | $12M | $9M | $9M | $6M | $7M | $8M | $9M | $10M | $10M | $6M | $3M | $0 | $133.0K | |
| Other Non-op | $10M | $9M | $9M | $6M | $7M | $8M | $9M | $10M | $10M | $6M | $3M | $0 | $133.0K | |
| Pretax Income | $-86M | $-74M | $-69M | $-65M | $-66M | $-55M | $-67M | $-49M | $-34M | $-32M | · | · | · | |
| Income Tax | $78.0K | $79.0K | $62.0K | $61.0K | $72.0K | $83.0K | $18.0K | $0 | $0 | $0 | · | · | · | |
| Net Income | $-86M | $-74M | $-69M | $-65M | $-66M | $-55M | $-67M | $-49M | $-34M | $-32M | $-21M | $-19M | $-13M | |
| EPS (Basic) | $-1.14 | $-1.06 | $-1.03 | $-1.11 | $-1.13 | $-0.95 | $-1.20 | $-0.86 | $-0.60 | $-0.64 | $-0.51 | $-3.78 | $-2.51 | |
| EPS (Diluted) | $-1.14 | $-1.06 | $-1.03 | $-1.11 | $-1.13 | $-0.95 | $-1.20 | $-0.86 | $-0.60 | $-0.64 | $-0.51 | $-3.78 | $-2.51 | |
| Shares (Basic) | 75,443,496 | 69,668,439 | -114,706,527 | 58,773,731 | 58,428,344 | 58,195,272 | -108,306,384 | 56,795,544 | 56,515,003 | 50,189,808 | 41,231,379 | 5,000,000 | 5,000,000 | |
| Shares (Diluted) | 75,443,496 | 69,668,439 | -114,706,527 | 58,773,731 | 58,428,344 | 58,195,272 | -108,306,384 | 56,795,544 | 56,515,003 | 50,189,808 | 41,231,379 | 5,000,000 | 5,000,000 | |
| EBITDA | $-96M | $-83M | · | $-71M | $-73M | $-63M | · | $-59M | $-44M | $-38M | $-24M | $-19M | · |
Balance general 20
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $106M | $452M | $132M | $108M | $124M | $107M | $142M | $119M | $307M | $485M | · | $125M | · | |
| Short-term Investments | $866M | $608M | $599M | $419M | $381M | $406M | $379M | $407M | $369M | $331M | $235M | · | · | |
| Prepaid Expense | $20M | $14M | $11M | $13M | $11M | $8M | $9M | $8M | $6M | $4M | $4M | $6M | · | |
| Other Current Assets | $1M | $1M | $605.0K | $919.0K | $963.0K | $586.0K | $2M | $396.0K | $3M | $3M | $1M | $887.0K | · | |
| Current Assets | $992M | $1.07B | $741M | $540M | $516M | $522M | $530M | $534M | $682M | $821M | $426M | $131M | · | |
| PP&E (Net) | $5M | $5M | $6M | $6M | $6M | $6M | $2M | $1M | $714.0K | $699.0K | · | · | · | |
| Accum. Depreciation | $2M | $2M | $2M | $1M | $796.0K | $396.0K | $189.0K | $113.0K | · | · | · | · | · | |
| Other Non-current Assets | $11M | $9M | $9M | $9M | $9M | $7M | $498.0K | $514.0K | $468.0K | $401.0K | · | · | · | |
| Total Assets | $1.34B | $1.29B | $937M | $626M | $658M | $714M | $754M | $776M | $801M | $824M | $426M | $131M | · | |
| Accounts Payable | $3M | $1M | $1M | $376.0K | $6M | $2M | $1M | $2M | $6M | $4M | $1M | $11M | · | |
| Accrued Liabilities | $32M | $29M | $23M | $30M | $22M | $27M | $24M | $28M | $17M | $16M | $16M | $6M | · | |
| Current Liabilities | $38M | $33M | $28M | $34M | $32M | $33M | $29M | $33M | $25M | $22M | $17M | $18M | · | |
| Capital Leases | $4M | $5M | $5M | $6M | $7M | $8M | $9M | $9M | $2M | $630.0K | · | · | · | |
| Total Liabilities | $141M | $38M | $33M | $40M | $38M | $41M | $37M | $42M | $27M | $22M | $17M | $18M | · | |
| Common Stock | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | · | · | · | |
| Paid-in Capital | $1.92B | $1.89B | $1.46B | $1.08B | $1.05B | $1.03B | $1.02B | $970M | $964M | $958M | $501M | · | · | |
| Retained Earnings | $-722M | $-636M | $-562M | $-492M | $-427M | $-361M | $-306M | $-239M | $-190M | $-156M | $-92M | $-71M | · | |
| AOCI | $-3M | $-749.0K | $1M | $1M | $685.0K | $1M | $915.0K | $3M | $-289.0K | $-177.0K | $135.0K | · | · | |
| Liabilities + Equity | $1.34B | $1.29B | $937M | $626M | $658M | $714M | $754M | $776M | $801M | $824M | $426M | $131M | · | |
| Shares Outstanding | 75,339,499 | 74,882,396 | 68,401,349 | 59,315,738 | 58,560,525 | 58,304,801 | 58,062,898 | 56,899,295 | 56,676,465 | 56,367,802 | 48,017,621 | · | · |
Flujo de Efectivo 9
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $17M | $17M | $12M | $12M | $11M | $11M | $8M | $6M | $6M | $4M | $2M | $1M | $1M | |
| Operating Cash Flow | $-71M | $-56M | $-63M | $-54M | $-62M | $-48M | $-68M | $-43M | $-29M | $-32M | $-20M | $-15M | $-11M | |
| CapEx | · | · | $62.0K | $0 | $768.0K | $4M | $-1.0K | $751.0K | $51.0K | $351.0K | · | · | · | |
| Investing Cash Flow | $-382M | $-35M | $-289M | $18M | $78M | $13M | $46M | $-146M | $-149M | $-52M | · | · | · | |
| Stock Issued | $-728.0K | $378M | · | $0 | $0 | $0 | · | $0 | $-541.0K | $450M | · | · | · | |
| Net Stock Activity | · | $378M | · | · | · | $0 | · | · | · | $450M | · | · | · | |
| Financing Cash Flow | $107M | $411M | $375M | $20M | $1M | $622.0K | $44M | $383.0K | $-150.0K | $451M | $317M | · | · | |
| Net Change in Cash | $-346M | $320M | $24M | $-17M | $17M | $-35M | $23M | $-189M | $-178M | $367M | $63M | $-16M | $-11M | |
| Free Cash Flow | · | · | · | · | · | $-53M | · | · | · | $-32M | · | · | · |
Rentabilidad 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -8.6% | -7.4% | · | -9.3% | -9.1% | -7.2% | · | -8.2% | -7.3% | -7.8% | -9.8% | -28.9% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 26.4 | 32.6 | · | 15.9 | 16.4 | 15.8 | · | 16.4 | 27.7 | 38.1 | 24.8 | 7.4 | · | |
| Quick Ratio | 25.9 | 32.2 | · | 15.5 | 16.0 | 15.6 | · | 16.1 | 27.5 | 37.9 | 13.7 | 7.1 | · |
Valoración (TTM) 6
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-291M | $-261M | · | $-235M | $-204M | $-170M | · | $-136M | $-106M | $-84M | $-72M | $-53M | · | |
| Market Cap | $10.00B | $6.30B | · | $2.36B | $2.54B | $2.18B | · | $3.34B | $2.23B | $3.75B | $1.02B | · | · | |
| P/E | -29.9 | -19.8 | · | -9.8 | -12.3 | -12.2 | · | -22.5 | -7.1 | -8.9 | -1.3 | · | · | |
| P / Cash Flow | · | -113.4 | · | · | · | -44.9 | · | · | · | -118.4 | · | · | · | |
| P / FCF | · | · | · | · | · | -41.3 | · | · | · | -117.1 | · | · | · | |
| Earnings Yield | -3.4% | -5.1% | · | -10.2% | -8.2% | -8.2% | · | -4.4% | -14.1% | -11.2% | -76.3% | · | · |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Beneficio neto | $-256M | $-182M | $-84M | $-40M |
| EPS Diluido | $-4.22 | $-3.30 | $-3.36 | $-16.16 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Ratio corriente | 26.6 | 18.5 | 19.4 | — |
| Ratio Rápido | 26.2 | 18.2 | 19.2 | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Flujo de caja libre | $-233M | $-172M | $-75M | — |
Últimas noticias Noticias recientes que mencionan a esta empresa
- Is AbbVie a Buy After Its Purchase of Apogee?
- AbbVie Just Sparked a 46% Rally in Apogee. Here’s Why This $10.9 Billion Deal Could Be a Win for AbbVie Investors.
- Apogee Therapeutics (APGE) Hits Fresh High on AbbVie $10.9B Merger
- The $11 Billion Reason Abbvie Stock Is Up Today
- Stock Market Today, June 22: Apogee Therapeutics Soars on AbbVie Cash Buyout Offer
- AbbVie to acquire Apogee Therapeutics in $10.9B deal
- VR Adviser Agrega Más de 1 Millón de Acciones de Savara
Mis Métricas Tu lista de seguimiento personal — filas seleccionadas de Fundamentales Completos
📊
Elige las métricas que te importan — haz clic en el ➕ junto a cualquier fila en Fundamentales Completos arriba.
Tu selección se guarda y te sigue en todos los tickers.
Propietarios institucionales (13F) 315 declarantes · $7.1B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 130 (+75 vs trimestre anterior) | 47 (+20 vs trimestre anterior) | 81 (-23 vs trimestre anterior) | 67 (+17 vs trimestre anterior) | -4.7M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Venrock Adviser, LLC | $1 127 318 496 | 8 493 321 | 15,92% | Acciones |
| HBK INVESTMENTS L P | $378 280 500 | 2 850 000 | 5,34% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $341 397 355 | 2 572 119 | 4,82% | Acciones |
| STATE STREET CORP | $304 979 428 | 2 297 743 | 4,31% | Acciones |
| FMR LLC | $241 465 867 | 1 819 226 | 3,41% | Acciones |
| Driehaus Capital Management LLC | $230 963 606 | 1 740 101 | 3,26% | Acciones |
| Balyasny Asset Management L.P. | $221 006 068 | 1 665 080 | 3,12% | Acciones |
| Paradigm Biocapital Advisors LP | $209 233 581 | 1 576 385 | 2,95% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $202 910 988 | 1 528 750 | 2,86% | Acciones |
| GOLDMAN SACHS GROUP INC | $201 319 157 | 1 516 757 | 2,84% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $197 954 053 | 1 491 404 | 2,79% | Acciones |
| Pentwater Capital Management LP | $189 140 250 | 1 425 000 | 2,67% | Acciones |
| PERCEPTIVE ADVISORS LLC | $173 625 838 | 1 308 113 | 2,45% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $149 266 292 | 1 124 299 | 2,11% | Acciones |
| Affinity Asset Advisors, LLC | $131 004 510 | 987 000 | 1,85% | Acciones |
| MERCER GLOBAL ADVISORS INC /ADV | $124 936 493 | 941 283 | 1,76% | Acciones |
| First Light Asset Management, LLC | $123 477 259 | 930 289 | 1,74% | Acciones |
| Kryger Capital LLC | $98 559 325 | 742 555 | 1,39% | Acciones |
| Qube Research & Technologies Ltd | $87 559 061 | 659 678 | 1,24% | Acciones |
| First Trust Capital Management L.P. | $82 980 407 | 625 182 | 1,17% | Acciones |
| Remedium Capital Partners, LLC | $77 871 496 | 586 691 | 1,10% | Acciones |
| BANK OF AMERICA CORP /DE/ | $76 695 907 | 577 834 | 1,08% | Acciones |
| SOROS FUND MANAGEMENT LLC | $74 926 085 | 564 500 | 1,06% | Acciones |
| Balyasny Asset Management L.P. | $66 365 000 | 500 000 | 0,94% | Opción de venta |
| ALLIANCEBERNSTEIN L.P. | $65 236 632 | 775 058 | 0,92% | Acciones |
| Woodline Partners LP | $61 669 278 | 464 622 | 0,87% | Acciones |
| WHITEBOX ADVISORS LLC | $59 728 633 | 450 001 | 0,84% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $58 886 726 | 443 658 | 0,83% | Acciones |
| AQR Arbitrage LLC | $57 060 627 | 429 900 | 0,81% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $52 186 781 | 393 180 | 0,74% | Acciones |
| Opaleye Management Inc. | $51 764 700 | 390 000 | 0,73% | Acciones |
| TIG Advisors, LLC | $48 346 902 | 364 250 | 0,68% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $48 264 344 | 363 628 | 0,68% | Acciones |
| Cinctive Capital Management LP | $46 477 400 | 350 165 | 0,66% | Acciones |
| Polar Asset Management Partners Inc. | $42 801 045 | 322 467 | 0,60% | Acciones |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $40 315 285 | 303 739 | 0,57% | Acciones |
| Fairmount Funds Management LLC | $39 639 416 | 298 647 | 0,56% | Acciones |
| NEXPOINT ASSET MANAGEMENT, L.P. | $38 814 234 | 292 430 | 0,55% | Acciones |
| Squarepoint Ops LLC | $38 586 336 | 290 713 | 0,54% | Acciones |
| CITIGROUP INC | $38 075 061 | 286 861 | 0,54% | Acciones |
| LOOMIS SAYLES & CO L P | $37 377 830 | 281 608 | 0,53% | Acciones |
| Magnetar Financial LLC | $36 502 741 | 275 015 | 0,52% | Acciones |
| Slotnik Capital, LLC | $34 608 020 | 260 740 | 0,49% | Acciones |
| Man Group plc | $34 552 274 | 260 320 | 0,49% | Acciones |
| EVENTIDE ASSET MANAGEMENT, LLC | $34 509 800 | 260 000 | 0,49% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $33 182 500 | 250 000 | 0,47% | Acciones |
| D. E. Shaw & Co., Inc. | $32 107 785 | 241 903 | 0,45% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $27 901 439 | 210 212 | 0,39% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $26 917 644 | 202 800 | 0,38% | Opción de venta |
| PICTON MAHONEY ASSET MANAGEMENT | $26 546 000 | 200 000 | 0,37% | Opción de venta |
| VANGUARD GROUP INC | $24 556 890 | 325 343 | 0,35% | Acciones |
| MUFG Securities EMEA plc | $23 957 765 | 180 500 | 0,34% | Acciones |
| Allianz Asset Management GmbH | $23 493 210 | 177 000 | 0,33% | Acciones |
| PICTON MAHONEY ASSET MANAGEMENT | $21 900 456 | 165 000 | 0,31% | Acciones |
| Verition Fund Management LLC | $21 138 049 | 159 256 | 0,30% | Acciones |
| BlackRock, Inc. | $20 914 133 | 157 569 | 0,30% | Acciones |
| HIGHBRIDGE CAPITAL MANAGEMENT LLC | $20 668 197 | 155 857 | 0,29% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $19 484 764 | 146 800 | 0,28% | Acciones |
| First Turn Management, LLC | $18 425 844 | 138 822 | 0,26% | Acciones |
| Grantham, Mayo, Van Otterloo & Co. LLC | $18 236 438 | 137 395 | 0,26% | Acciones |
| Sagefield Capital LP | $17 970 846 | 135 394 | 0,25% | Acciones |
| GABELLI FUNDS LLC | $16 894 007 | 127 281 | 0,24% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $16 094 574 | 121 258 | 0,23% | Acciones |
| CAPSTONE INVESTMENT ADVISORS, LLC | $15 927 600 | 120 000 | 0,22% | Acciones |
| Twin Securities, Inc. | $15 927 600 | 120 000 | 0,22% | Acciones |
| Melqart Asset Management (UK) Ltd | $15 562 460 | 117 249 | 0,22% | Acciones |
| Caption Management, LLC | $15 356 861 | 115 700 | 0,22% | Opción de venta |
| TUDOR INVESTMENT CORP ET AL | $13 352 638 | 100 600 | 0,19% | Opción de venta |
| SEVEN GRAND MANAGERS, LLC | $13 273 000 | 100 000 | 0,19% | Acciones |
| WATER ISLAND CAPITAL LLC | $12 596 077 | 94 900 | 0,18% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $12 577 362 | 94 759 | 0,18% | Acciones |
| Maven Securities LTD | $12 080 819 | 91 018 | 0,17% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $11 674 002 | 87 953 | 0,16% | Acciones |
| ExodusPoint Capital Management, LP | $11 608 625 | 87 500 | 0,16% | Opción de compra |
| GABELLI & Co INVESTMENT ADVISERS, INC. | $10 836 741 | 81 645 | 0,15% | Acciones |
| GARDNER LEWIS ASSET MANAGEMENT L P | $10 618 400 | 80 000 | 0,15% | Acciones |
| Candriam S.C.A. | $10 566 281 | 79 684 | 0,15% | Acciones |
| HARVEST MANAGEMENT LLC | $10 485 670 | 79 000 | 0,15% | Acciones |
| Swiss National Bank | $10 180 391 | 76 700 | 0,14% | Acciones |
| WCM INVESTMENT MANAGEMENT, LLC | $10 074 912 | 75 974 | 0,14% | Acciones |
| Alberta Investment Management Corp | $9 954 750 | 75 000 | 0,14% | Acciones |
| Chicago Capital Management, LLC | $9 807 420 | 97 100 | 0,14% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9 768 928 | 73 600 | 0,14% | Opción de compra |
| Boxer Capital Management, LLC | $9 291 100 | 70 000 | 0,13% | Acciones |
| PRUDENTIAL FINANCIAL INC | $8 510 648 | 64 120 | 0,12% | Acciones |
| KENNEDY CAPITAL MANAGEMENT LLC | $8 492 198 | 63 981 | 0,12% | Acciones |
| CREDIT INDUSTRIEL ET COMMERCIAL | $8 418 268 | 63 424 | 0,12% | Acciones |
| ALPS ADVISORS INC | $8 298 678 | 62 523 | 0,12% | Acciones |
| Westchester Capital Management, LLC | $8 253 417 | 62 182 | 0,12% | Acciones |
| Beryl Capital Management LLC | $7 788 065 | 58 676 | 0,11% | Acciones |
| PRELUDE CAPITAL MANAGEMENT, LLC | $7 776 651 | 58 590 | 0,11% | Acciones |
| PLATINUM INVESTMENT MANAGEMENT LTD | $7 740 017 | 58 314 | 0,11% | Acciones |
| ALPINE ASSOCIATES MANAGEMENT INC. | $7 685 067 | 57 900 | 0,11% | Acciones |
| RHUMBLINE ADVISERS | $7 514 630 | 56 616 | 0,11% | Acciones |
| Point72 Asset Management, L.P. | $7 241 616 | 54 559 | 0,10% | Acciones |
| FIRST TRUST ADVISORS LP | $7 073 447 | 53 292 | 0,10% | Acciones |
| ABC ARBITRAGE SA | $7 023 806 | 52 918 | 0,10% | Acciones |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $6 755 957 | 50 900 | 0,10% | Acciones |
| Centiva Capital, LP | $6 650 038 | 50 102 | 0,09% | Acciones |
| Symmetry Investments LP | $6 636 500 | 50 000 | 0,09% | Opción de compra |
Informantes de la empresa 9 insiders · 2 directivos · 7 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Michael Thomas Henderson | Chief Executive Officer | 10 de julio de 2026 G | 920 941 | 0 | 33 | $-28 389 804 |
| Jane Henderson | Chief Financial Officer | 24 de julio de 2026 G | 158 371 | 0 | 22 | $-2 092 806 |
| Lisa Bollinger | Consejero | 9 de junio de 2026 A | — | 0 | 0 | $0 |
| Jennifer A. Fox | Consejero | 9 de junio de 2026 A | — | 0 | 0 | $0 |
| Mark C. Mckenna | Consejero | 9 de junio de 2026 A | 20 000 | 0 | 0 | $0 |
| Nimish P Shah | Consejero | 9 de junio de 2026 A | 1 750 000 | 0 | 0 | $0 |
| William A Jones JR | Consejero | 9 de junio de 2026 A | — | 0 | 0 | $0 |
| Andrew Gottesdiener | Consejero | 17 de junio de 2025 A | — | 0 | 0 | $0 |
| Carl Dambkowski | — | 5 de agosto de 2026 M | 168 498 | 0 | 29 | $-10 257 229 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 2 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC, Fairmount Healthcare Fund II L.P., Peter Evan Harwin, Tomas Kiselak ×7 presentaciones | 23 de junio de 2026 | 9,99% | Enmienda | — | SEC |
| Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Shah, Nimish, Koh, Bong | 28 de julio de 2023 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 49 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 2,93% | 57 722 NS | 31 de mayo de 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 1,97% | 4 823 NS | 31 de mayo de 2026 | N-PORT |
| GURU · Global X Funds | 1,29% | 9 059 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 1,04% | 65 006 NS | 30 de abril de 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,86% | 1 152 NS | 30 de abril de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,79% | 3 580 NS | 30 de abril de 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,64% | 4 048 NS | 31 de mayo de 2026 | N-PORT |
| IBB · iShares Trust | 0,59% | 418 176 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,57% | 3 368 SH | 8 de agosto de 2026 | Diario |
| FSCC · Federated Hermes ETF Trust | 0,50% | 16 880 NS | 31 de mayo de 2026 | N-PORT |
| IWO · iShares Trust | 0,37% | 408 942 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,35% | 48 245 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,23% | 2 028 NS | 31 de mayo de 2026 | N-PORT |
| IWM · iShares Trust | 0,19% | 1 143 929 SH | 8 de agosto de 2026 | Diario |
| BKSE · BNY Mellon ETF Trust | 0,19% | 1 817 NS | 30 de abril de 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,18% | 259 546 SH | 8 de agosto de 2026 | Diario |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,17% | 15 226 NS | 30 de abril de 2026 | N-PORT |
| ISCG · iShares Trust | 0,17% | 12 662 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,11% | 19 243 NS | 30 de abril de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,09% | 258 020 NS | 31 de mayo de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,09% | 2 095 NS | 31 de mayo de 2026 | N-PORT |
| ISCB · iShares Trust | 0,08% | 1 801 SH | 8 de agosto de 2026 | Diario |
| VXF · VANGUARD INDEX FUNDS | 0,08% | 641 337 SH | 8 de agosto de 2026 | Diario |
| VBR · VANGUARD INDEX FUNDS | 0,08% | 428 167 SH | 8 de agosto de 2026 | Diario |
| ESML · iShares Trust | 0,08% | 17 140 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,07% | 114 655 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,05% | 1 637 NS | 31 de mayo de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,05% | 11 341 SH | 8 de agosto de 2026 | Diario |
| FHLC · FIDELITY COVINGTON TRUST | 0,05% | 17 612 NS | 30 de abril de 2026 | N-PORT |
| VB · VANGUARD INDEX FUNDS | 0,05% | 674 464 SH | 8 de agosto de 2026 | Diario |
| WSML · iShares Trust | 0,05% | 2 338 SH | 8 de agosto de 2026 | Diario |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,05% | 58 NS | 31 de mayo de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,04% | 4 882 NS | 31 de mayo de 2026 | N-PORT |
| URTY · ProShares Trust | 0,04% | 1 660 NS | 31 de mayo de 2026 | N-PORT |
| SMLF · iShares Trust | 0,03% | 10 566 SH | 8 de agosto de 2026 | Diario |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,02% | 1 535 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,02% | 42 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 15 716 NS | 31 de mayo de 2026 | N-PORT |
| FBCG · FIDELITY COVINGTON TRUST | 0,01% | 8 874 NS | 30 de abril de 2026 | N-PORT |
| ITOT · iShares Trust | 0,01% | 75 741 SH | 8 de agosto de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | 0,01% | 1 871 044 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,01% | 3 673 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,01% | 11 143 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,01% | 31 667 NS | 31 de mayo de 2026 | N-PORT |
| TILT · FlexShares Trust | 0,00% | 924 NS | 30 de abril de 2026 | N-PORT |
| AVLC · AMERICAN CENTURY ETF TRUST | 0,00% | 106 NS | 31 de mayo de 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 17 NS | 31 de mayo de 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 52 NS | 31 de mayo de 2026 | N-PORT |
| FTLS · First Trust Exchange-Traded Fund III | -0,06% | -17 470 NS | 30 de abril de 2026 | N-PORT |