CDXS Codexis, Inc. - Common Stock

NASDAQ · Life Sciences Tools & Services · Ver en SEC EDGAR ↗
$1,57
Precio · Ago 18, 2026
Fundamentales a fecha de Ago 11, 2026

Acerca de Codexis, Inc. - Common Stock Descripción general de la empresa de Wikipedia

Codexis, Inc. is a protein engineering company that develops enzymes for pharmaceutical, food and medical applications.

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Codexis, Inc. is a protein engineering company that develops enzymes for pharmaceutical, food and medical applications.

History

Codexis is based in Redwood City, CA and was incorporated in 2002. It went public in April 2010 on NASDAQ, and in October, acquired Maxygen's MolecularBreeding technology portfolio.

Pharmaceutical

Codexis won the Presidential Green Chemistry Challenge Award from the U.S. Environmental Protection Agency (EPA) in 2006 for its work on a building block of Lipitor. It then won a second time in 2010 for its work with Merck & Co. on the active ingredient in Januvia.

Nutrition

In 2017, the company entered a partnership with Tate & Lyle to provide research and development for the production of new ingredients. That same year, Codexis announced a collaboration with Nestle to provide enzymes for metabolic disorders.

Biotherapeutics

In 2017, Codexis developed a recombinant phenylalanine ammonia-lyase (PAL) enzyme, to act as a substitute phenylalanine hydroxylase (PAH) enzyme for people who suffer from phenylketonuria. The enzyme was in-licensed by Nestle Health Sciences.

In 2020, Takeda Pharmaceutical announced a collaboration with Codexis to research and create gene therapies for rare diseases, including lysosomal storage disorders.

Life science

In June 2020, they announced a partnership with Molecular Assemblies to engineer enzymes for DNA synthesis.

Technology

Codexis uses directed evolution to develop its enzymes. Using this method, scientists genetically engineer genes, then screen the enzymes produced to see if it creates the properties needed for a specific reaction. Their protein engineering platform, called CodeEvolver, uses machine learning and high-throughput experimentation to learn protein sequence changes and their impacts on protein function.

Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗

Wikidata ↗

CDXS Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas

Precio
$1.56
Capitalización Bursátil
$142M
P/E (TTM)
-3.1
BPA (TTM)
$-0.50
Ingresos (TTM)
$70M
Rendimiento div.
ROE
-82.8%
Deuda/Capital
0.8
Rango 52S
$1 – $3

CDXS Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista

Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA

Ingresos y Beneficio Neto $70M
10-point trend, +44.1%
2016-12-31 2025-12-31
BPA $-0.50
7-point trend, -138.1%
2019-12-31 2025-12-31
Flujo de caja libre $-24M
10-point trend, -564.4%
2016-12-31 2025-12-31
Márgenes -62.5%

Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?

Métrica
Tendencia a 5 años
CDXS
Mediana de Pares
P/E (TTM)
5-point trend, +96.6%
-3.1
17.5
P/S (TTM) (P/V (TTM))
5-point trend, -89.2%
2.0
3.3
P/B (P/C)
5-point trend, -76.4%
2.8
2.1
EV / EBITDA
3-point trend, +81.5%
-2.8
Price / FCF (Precio / FCF)
5-point trend, +91.5%
-5.9

Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC

Métrica
Tendencia a 5 años
CDXS
Mediana de Pares
Operating Margin (Margen Operativo)
5-point trend, -173.7%
-59.3%
Net Profit Margin (Margen de Beneficio Neto)
5-point trend, -207.6%
-62.5%
-56.5%
ROA
5-point trend, -226.0%
-29.6%
-17.2%
ROE
5-point trend, -549.2%
-82.8%
-41.3%
ROIC
5-point trend, -230.9%
-46.1%

Salud financiera Deuda, liquidez, solvencia — solidez del balance general

Métrica
Tendencia a 5 años
CDXS
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
3-point trend, +6352.8%
0.8
369.6
Current Ratio (Ratio corriente)
5-point trend, -21.2%
3.8
4.9
Quick Ratio (Ratio Rápido)
5-point trend, -27.3%
3.1

Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años

Métrica
Tendencia a 5 años
CDXS
Mediana de Pares
Revenue YoY (Ingresos interanuales)
5-point trend, -32.8%
18.6%
Revenue CAGR 3Y (Ingresos CAGR 3A)
5-point trend, -32.8%
-20.2%
Revenue CAGR 5Y (Ingresos CAGR 5A)
5-point trend, -32.8%
0.38%

Métricas por acción BPA, valor contable por acción, flujo de caja por acción, dividendo por acción

Métrica
Tendencia a 5 años
CDXS
Mediana de Pares
EPS (Diluted) (BPA (Diluido))
5-point trend, -51.5%
$-0.50

Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar

Métrica
Tendencia a 5 años
CDXS
Mediana de Pares

CDXS Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista

COMPRA 13 analistas
  • Compra fuerte 4 30,8%
  • Compra 6 46,2%
  • Mantener 3 23,1%
  • Venta 0 0,0%
  • Venta fuerte 0 0,0%

Precio objetivo a 12 meses

6 analistas · 2026-08-13
Objetivo mediano $7.00 +347,3%
Objetivo medio $6.58 +320,7%

Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados

Sorpresa Media
0.01%
Período EPS Actual EPS est. Sorpresa
30 de junio de 2026 $-0.13 $-0.14 0.01%
31 de marzo de 2026 $-0.10 $-0.14 0.04%
31 de diciembre de 2025 $0.11 $-0.04 0.15%
30 de septiembre de 2025 $-0.22 $-0.15 -0.07%
30 de junio de 2025 $-0.16 $-0.19 0.03%
31 de marzo de 2025 $-0.25 $-0.24 -0.01%
31 de diciembre de 2024 $-0.13 $-0.04 -0.09%

Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector

Ticker Capitalización Bursátil P/E Ingresos interanuales Margen Neto ROE Margen Bruto
CDXS $147M -3.3 18.6% -62.5% -82.8%
DNA $484M -1.5 -25.1% -183.8% -55.8%
TKNO $204M -11.9 7.3% -42.6% -23.8% 33.2%
PACB $565M -1.0 3.9% -341.5% -1634.9% 28.6%
LAB $495M -6.4 -6.2% -87.8% -17.6% 49.9%
LFCR $249M -5.3 0.47% -30.0% -461.3% 31.3%
QSI
MXCT $166M -3.7 -14.5% -135.1% -24.6% 81.2%
QTRX $297M -2.5 1.1% -77.1% -36.4% 46.8%
SEER -1.4 17.0%
NAUT $247M -4.1 -34.9%

Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja

Estado de resultados 16
Datos anuales de Estado de resultados para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +99.4% $70M $59M $70M $139M $105M $69M $68M $61M $50M $49M $42M $35M
Cost of Revenue 12-point trend, -4.0% $9M $16M $13M $38M $22M $14M $16M $13M $14M $10M $7M $10M
R&D Expense 12-point trend, +129.9% $52M $46M $59M $80M $56M $44M $34M $30M $30M $22M $21M $23M
SG&A Expense 12-point trend, +114.6% $47M $55M $53M $52M $49M $35M $32M $29M $29M $25M $22M $22M
Operating Expenses 12-point trend, +106.0% $112M $118M $138M $173M $127M $93M $81M $72M $73M $57M $50M $54M
Operating Income 12-point trend, -118.4% $-42M $-59M $-68M $-35M $-23M $-24M $-13M $-11M $-23M $-9M $-8M $-19M
Interest Income 12-point trend, +14483.3% $3M $4M $4M $1M $459.0K $405.0K $1M $671.0K $147.0K $60.0K $19.0K $18.0K
Other Non-op 10-point trend, -5020.2% $-5M $-10M $-12M $124.0K $1M $-156.0K $-656.0K $-291.0K $-92.0K $-94.0K · ·
Pretax Income 12-point trend, -127.3% $-44M $-65M $-76M $-33M $-21M $-24M $-12M $-11M $-23M $-9M $-8M $-19M
Income Tax 12-point trend, +118.4% $47.0K $34.0K $69.0K $276.0K $189.0K $339.0K $17.0K $-37.0K $81.0K $-40.0K $-338.0K $-256.0K
Net Income 12-point trend, -130.6% $-44M $-65M $-76M $-34M $-21M $-24M $-12M $-11M $-23M $-9M $-8M $-19M
EPS (Basic) 7-point trend, -138.1% $-0.50 $-0.89 $-1.12 $-0.51 $-0.33 $-0.40 $-0.21 · · · · ·
EPS (Diluted) 7-point trend, -138.1% $-0.50 $-0.89 $-1.12 $-0.51 $-0.33 $-0.40 $-0.21 · · · · ·
Shares (Basic) 7-point trend, +54.2% 87,142,000 73,408,000 68,131,000 65,344,000 64,568,000 59,360,000 56,525,000 · · · · ·
Shares (Diluted) 7-point trend, +54.2% 87,142,000 73,408,000 68,131,000 65,344,000 64,568,000 59,360,000 56,525,000 · · · · ·
EBITDA 12-point trend, -90.9% $-36M $-54M $-68M $-35M $-23M $-24M $-13M $-11M $-23M $-9M $-8M $-19M
Balance general 29
Datos anuales de Balance general para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +91.8% $51M $19M $65M $114M $117M $149M $90M $53M $31M $19M $23M $26M
Short-term Investments 3-point trend, +27416000.00 $27M $54M $0 · · · · · · · · ·
Receivables 10-point trend, +159.3% · · $10M $32M $25M $14M $9M $12M $11M $6M $7M $4M
Inventory 12-point trend, +30.3% $2M $2M $3M $2M $1M $964.0K $371.0K $589.0K $1M $825.0K $992.0K $1M
Prepaid Expense 12-point trend, +348.3% $6M $4M $5M $5M $6M $3M $3M $1M $984.0K $1M $1M $1M
Other Current Assets 4-point trend, -28.6% $500.0K $500.0K $600.0K $700.0K · · · · · · · ·
Current Assets 12-point trend, +193.3% $97M $99M $93M $163M $162M $184M $114M $68M $45M $27M $33M $33M
PP&E (Net) 12-point trend, +226.0% $13M $14M $15M $23M $21M $10M $6M $5M $3M $2M $3M $4M
PP&E (Gross) 12-point trend, +56.3% $58M $55M $55M $62M $57M $43M $40M $38M $35M $34M $35M $37M
Accum. Depreciation 12-point trend, +43.8% $45M $41M $39M $40M $36M $33M $33M $33M $32M $32M $32M $31M
Goodwill 12-point trend, -24.0% $2M $2M $2M $3M $3M $3M $3M $3M $3M $3M $3M $3M
Intangibles 3-point trend, -100.0% · · · · · · · · · $0 $3M $6M
Other Non-current Assets 12-point trend, +200.3% $883.0K $1M $1M $350.0K $276.0K $294.0K $178.0K $1M $302.0K $259.0K $310.0K $294.0K
Total Assets 12-point trend, +207.1% $148M $149M $137M $250M $246M $222M $149M $79M $54M $36M $45M $48M
Accounts Payable 12-point trend, -66.7% $2M $3M $6M $3M $3M $3M $3M $3M $4M $4M $3M $5M
Accrued Liabilities 12-point trend, +5.7% $3M $6M $5M $15M $13M $10M $7M $5M $4M $2M $2M $3M
Current Liabilities 12-point trend, +84.3% $25M $24M $36M $49M $33M $25M $15M $18M $25M $12M $15M $14M
Capital Leases 9-point trend, +9886.4% $30M $28M $12M $38M $44M $22M $25M $61.0K $302.0K · · ·
Other Non-current Liabilities 12-point trend, -47.5% $1M $1M $1M $1M $1M $1M $1M $1M $2M $2M $2M $3M
Total Liabilities 11-point trend, +346.8% $97M $82M $50M $106M $82M $52M $44M $23M $29M $17M $22M ·
Long-term Debt 2-point trend, +38.7% $40M $29M · · · · · · · · · ·
Total Debt 3-point trend, +13179.8% $40M $29M · · · · · · $302.0K · · ·
Common Stock 12-point trend, +125.0% $9.0K $8.0K $7.0K $6.0K $6.0K $6.0K $6.0K $5.0K $5.0K $4.0K $4.0K $4.0K
Paid-in Capital 12-point trend, +117.4% $657M $630M $584M $566M $552M $537M $448M $387M $340M $311M $306M $302M
Retained Earnings 12-point trend, -119.9% $-607M $-563M $-498M $-421M $-388M $-366M $-342M $-330M $-315M $-292M $-284M $-276M
AOCI 8-point trend, +105.6% $8.0K $52.0K $0 · · · · $0 $-472.0K $0 $405.0K $-142.0K
Stockholders' Equity 12-point trend, +92.0% $51M $67M $87M $145M $164M $170M $106M $56M $25M $19M $23M $26M
Liabilities + Equity 12-point trend, +207.1% $148M $149M $137M $250M $246M $222M $149M $79M $54M $36M $45M $48M
Shares Outstanding 12-point trend, +128.7% 90,478,000 81,850,000 69,905,000 65,811,000 65,109,000 64,283,000 58,877,000 54,065,000 48,365,000 41,255,000 40,343,000 39,563,000
Flujo de Efectivo 17
Datos anuales de Flujo de Efectivo para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
D&A 4-point trend, -2.9% $5M $5M $6M $5M · · · · · · · ·
Stock-based Comp 12-point trend, +108.3% $10M $13M $10M $15M $12M $8M $7M $8M $7M $6M $5M $5M
Deferred Tax 12-point trend, -102.7% $-3.0K $-2.0K $0 $-7.0K $-9.0K $-8.0K $-6.0K $-29.0K $12.0K $-31.0K $-330.0K $110.0K
Amort. of Intangibles 5-point trend, -100.0% · · · · · · · $0 $0 $3M $3M $3M
Restructuring 6-point trend, +3407000.00 $3M $0 $3M $3M $0 $0 · · · · · ·
Other Non-cash 2-point trend, +549.4% $10M $-2M · · · · · · · · · ·
Operating Cash Flow 12-point trend, -6136.1% $-19M $-49M $-53M $11M $-14M $-16M $-13M $-14M $-9M $-2M $-433.0K $321.0K
CapEx 12-point trend, +1380.5% $4M $4M $4M $8M $14M $4M $4M $3M $985.0K $888.0K $1M $302.0K
Investing Cash Flow 12-point trend, +405.7% $24M $-57M $-5M $-14M $-21M $-6M $-4M $-3M $-983.0K $-846.0K $-1M $5M
Debt Issued 4-point trend, +9897000.00 $10M $30M $0 $0 · · · · · · · ·
Net Debt Issued 2-point trend, -66.5% $10M $30M · · · · · · · · · ·
Stock Issued 12-point trend, +191755.6% $17M $31M $9M $0 $0 $86M $0 $37M $24M $0 $0 $9.0K
Net Stock Activity 11-point trend, +191755.6% $17M $31M $9M $0 $0 $86M $50M · $24M $0 $0 $9.0K
Financing Cash Flow 12-point trend, +4670.9% $28M $61M $8M $-575.0K $4M $81M $54M $39M $22M $-490.0K $-2M $-611.0K
Net Change in Cash 12-point trend, +635.7% $32M $-46M $-49M $-3M $-32M $59M $38M $22M $12M $-3M $-3M $4M
Taxes Paid 11-point trend, +13.3% · $17.0K $194.0K $100.0K $102.0K $312.0K $5.0K $5.0K $32.0K $5.0K $8.0K $15.0K
Free Cash Flow 12-point trend, -125610.5% $-24M $-54M $-57M $3M $-28M $-20M $-16M $-17M $-10M $-4M $-2M $19.0K
Rentabilidad 7
Datos anuales de Rentabilidad para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Operating Margin 12-point trend, -9.6% -59.3% -98.6% -97.0% -25.2% -21.7% -34.6% -18.3% -18.6% -45.9% -17.5% -18.6% -54.1%
Net Margin 12-point trend, -15.7% -62.5% -110.0% -108.7% -24.2% -20.3% -34.8% -17.4% -17.9% -46.0% -17.5% -18.1% -54.0%
Pretax Margin 12-point trend, -14.0% -62.4% -109.9% -108.6% -24.0% -20.1% -34.3% -17.4% -18.0% -45.8% -17.6% -18.9% -54.7%
EBITDA Margin 12-point trend, +4.2% -51.8% -90.3% -97.0% -25.2% -21.7% -34.6% -18.3% -18.6% -45.9% -17.5% -18.6% -54.1%
ROA 12-point trend, +16.9% -29.6% -45.7% -39.4% -13.5% -9.1% -13.0% -10.4% -16.4% -51.5% -21.3% -16.3% -35.7%
ROE 12-point trend, -47.2% -82.8% -93.0% -85.6% -22.5% -12.8% -18.4% -11.5% -19.6% -98.6% -40.8% -30.8% -56.3%
ROIC 12-point trend, +35.7% -46.1% -61.1% -78.7% -24.3% -13.9% -14.3% -11.9% -20.0% -92.8% -44.6% -32.5% -71.7%
Liquidez y Solvencia 4
Datos anuales de Liquidez y Solvencia para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, +59.1% 3.8 4.2 2.6 3.3 4.9 7.4 7.4 3.8 1.8 2.2 2.2 2.4
Quick Ratio 12-point trend, +39.8% 3.1 3.1 2.1 3.0 4.2 6.5 6.5 3.6 1.7 2.0 2.1 2.2
Debt / Equity 3-point trend, +6352.8% 0.8 0.4 · · · · · · 0.0 · · ·
LT Debt / Equity 3-point trend, +6352.8% 0.8 0.4 · · · · · · 0.0 · · ·
Eficiencia 3
Datos anuales de Eficiencia para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Asset Turnover 12-point trend, -28.2% 0.5 0.4 0.4 0.6 0.4 0.4 0.6 0.9 1.1 1.2 0.9 0.7
Inventory Turnover 12-point trend, -23.5% 5.2 7.3 5.4 23.9 20.9 20.6 32.6 15.5 15.4 10.7 5.5 6.7
Receivables Turnover 10-point trend, -56.0% · · 3.3 4.9 5.4 6.0 6.7 5.3 5.6 7.4 7.5 7.6
Por Acción 5
Datos anuales de Por Acción para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, -16.0% $0.56 $0.82 $1.24 $2.20 $2.52 $2.65 $1.79 $1.03 $0.51 $0.46 $0.57 $0.67
Revenue / Share 5-point trend, -50.2% $0.81 $0.81 $1.03 $2.12 $1.62 · · · · · · ·
Cash Flow / Share 5-point trend, -0.6% $-0.22 $-0.67 $-0.77 $0.17 $-0.22 · · · · · · ·
Cash / Share 12-point trend, -16.1% $0.56 $0.24 $0.93 $1.73 $1.79 $2.32 $1.54 $0.97 $0.65 $0.47 $0.58 $0.67
EPS (TTM) 7-point trend, -138.1% $-0.50 $-0.89 $-1.12 $-0.51 $-0.33 $-0.40 $-0.21 · · · · ·
Tasas de Crecimiento 3
Datos anuales de Tasas de Crecimiento para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -64.0% 18.6% -15.4% -49.4% 32.3% 51.7% · · · · · · ·
Revenue CAGR 3Y 3-point trend, -3988.5% -20.2% -17.3% 0.52% · · · · · · · · ·
Revenue CAGR 5Y 0.38% · · · · · · · · · · ·
Valoración (TTM) 14
Datos anuales de Valoración (TTM) para CDXS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +99.4% $70M $59M $70M $139M $105M $69M $68M $61M $50M $49M $42M $35M
Net Income TTM 12-point trend, -130.6% $-44M $-65M $-76M $-34M $-21M $-24M $-12M $-11M $-23M $-9M $-8M $-19M
Market Cap 12-point trend, +47.9% $147M $390M $213M $307M $2.04B $1.40B $941M $912M $404M $190M $171M $100M
Enterprise Value 3-point trend, -70.7% $109M $346M · · · · · · $373M · · ·
P/E 7-point trend, +95.7% -3.3 -5.4 -2.7 -9.1 -94.8 -54.6 -76.1 · · · · ·
P/S 12-point trend, -25.8% 2.1 6.6 3.0 2.2 19.4 20.3 13.8 15.0 8.1 3.9 4.1 2.8
P/B 12-point trend, -23.0% 2.9 5.8 2.5 2.1 12.4 8.2 8.9 16.2 16.5 9.9 7.5 3.8
P / Tangible Book 6-point trend, -63.5% 3.1 6.1 2.5 2.2 12.6 8.4 · · · · · ·
P / Cash Flow 12-point trend, -102.5% -7.6 -7.9 -4.1 27.2 -142.7 -85.2 -75.0 -64.7 -46.1 -70.3 -394.1 310.6
P / FCF 12-point trend, -100.1% -6.2 -7.3 -3.7 103.0 -72.5 -69.4 -57.8 -54.1 -41.4 -52.9 -104.6 5247.3
EV / EBITDA 3-point trend, +81.5% -3.0 -6.5 · · · · · · -16.2 · · ·
EV / FCF 3-point trend, +88.0% -4.6 -6.4 · · · · · · -38.3 · · ·
EV / Revenue 3-point trend, -79.2% 1.6 5.8 · · · · · · 7.5 · · ·
Earnings Yield 7-point trend, -2241.2% -30.7% -18.7% -36.7% -10.9% -1.1% -1.8% -1.3% · · · · ·

Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años

Estado de resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ingresos $70M$59M$70M$139M$105M
Margen Operativo % -59.3%-98.6%-97.0%-25.2%-21.7%
Beneficio neto $-44M$-65M$-76M$-34M$-21M
EPS Diluido $-0.50$-0.89$-1.12$-0.51$-0.33
Balance general
2025-12-312024-12-312023-12-312022-12-312021-12-31
Deuda / Patrimonio 0.80.4
Ratio corriente 3.84.22.63.34.9
Ratio Rápido 3.13.12.13.04.2
Flujo de Efectivo
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flujo de caja libre $-24M$-54M$-57M$3M$-28M

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Propietarios institucionales (13F) 156 declarantes · $120.9M total · A fecha de 30 de junio de 2026

Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.

Actividad institucional — Q2 2026 vs trimestre anterior
Nuevas posiciones Posiciones cerradas Aumentado Disminuido Cambio neto de acciones
32 (+4 vs trimestre anterior) 11 (-10 vs trimestre anterior) 50 (+4 vs trimestre anterior) 41 (+8 vs trimestre anterior) +6.7M

Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.

Institución Valor Acciones % de 13F rastreadas Tipo
Opaleye Management Inc. $15 334 100 6 785 000 12,69% Acciones
Aberdeen Group plc $15 300 096 6 769 954 12,66% Acciones
MILLENNIUM MANAGEMENT LLC $12 541 054 5 549 139 10,38% Acciones
Telemark Asset Management, LLC $8 692 889 3 846 411 7,19% Acciones
AMERIPRISE FINANCIAL INC $8 609 334 3 809 440 7,12% Acciones
Nantahala Capital Management, LLC $8 189 365 3 623 613 6,78% Acciones
VANGUARD CAPITAL MANAGEMENT LLC $8 174 666 3 617 109 6,76% Acciones
GEODE CAPITAL MANAGEMENT, LLC $4 204 899 1 860 140 3,48% Acciones
STATE STREET CORP $3 970 400 1 756 814 3,29% Acciones
JACOBS LEVY EQUITY MANAGEMENT, INC $3 006 263 1 330 205 2,49% Acciones
VANGUARD PORTFOLIO MANAGEMENT LLC $2 954 206 1 307 171 2,44% Acciones
Assenagon Asset Management S.A. $2 888 746 1 278 206 2,39% Acciones
D. E. Shaw & Co., Inc. $2 500 229 1 106 296 2,07% Acciones
Tallon Kerry Patrick $2 018 337 403 667 1,67% Acciones
TWO SIGMA INVESTMENTS, LP $1 574 314 696 599 1,30% Acciones
FRANKLIN RESOURCES INC $1 533 726 678 640 1,27% Acciones
VANGUARD FIDUCIARY TRUST CO $1 313 191 581 058 1,09% Acciones
Man Group plc $1 278 240 565 593 1,06% Acciones
Post Resch Tallon Group Inc. $1 273 460 563 478 1,05% Acciones
PERKINS CAPITAL MANAGEMENT INC $1 188 986 526 100 0,98% Acciones
ALGERT GLOBAL LLC $973 857 430 910 0,81% Acciones
TUDOR INVESTMENT CORP ET AL $808 910 357 925 0,67% Acciones
BlackRock, Inc. $648 681 287 027 0,54% Acciones
PLATINUM INVESTMENT MANAGEMENT LTD $597 689 264 464 0,49% Acciones
Potomac Capital Management, Inc. $587 600 260 000 0,49% Acciones
DIMENSIONAL FUND ADVISORS LP $583 674 258 263 0,48% Acciones
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $547 397 242 211 0,45% Acciones
XTX Topco Ltd $543 817 240 627 0,45% Acciones
UBS Group AG $542 188 239 906 0,45% Acciones
FMR LLC $457 501 202 434 0,38% Acciones
GOLDMAN SACHS GROUP INC $389 726 172 445 0,32% Acciones
Cubist Systematic Strategies, LLC $359 610 147 381 0,30% Acciones
BARCLAYS PLC $347 740 153 867 0,29% Acciones
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $334 595 148 051 0,28% Acciones
BRIDGEWAY CAPITAL MANAGEMENT, LLC $284 552 125 908 0,24% Acciones
STRS OHIO $273 460 121 000 0,23% Acciones
JANE STREET GROUP, LLC $261 857 115 866 0,22% Acciones
MARSHALL WACE, LLP $254 791 112 739 0,21% Acciones
Stonepine Capital Management, LLC $247 836 109 662 0,21% Acciones
RHUMBLINE ADVISERS $233 449 103 301 0,19% Acciones
CITADEL ADVISORS LLC $227 295 100 573 0,19% Acciones
ALLIANCEBERNSTEIN L.P. $206 081 126 430 0,17% Acciones
WELLS FARGO & COMPANY/MN $176 113 77 926 0,15% Acciones
Bank of New York Mellon Corp $174 178 77 070 0,14% Acciones
LPL Financial LLC $173 026 76 560 0,14% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $161 879 71 628 0,13% Acciones
BANK OF AMERICA CORP /DE/ $145 582 64 417 0,12% Acciones
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO $144 082 63 753 0,12% Acciones
Numerai GP LLC $136 072 60 209 0,11% Acciones
PANAGORA ASSET MANAGEMENT INC $131 532 58 200 0,11% Acciones
Mariner, LLC $123 484 54 637 0,10% Acciones
MetLife Investment Management, LLC $117 545 52 011 0,10% Acciones
ENVESTNET ASSET MANAGEMENT INC $116 108 51 375 0,10% Acciones
LOS ANGELES CAPITAL MANAGEMENT LLC $108 763 48 125 0,09% Acciones
IEQ CAPITAL, LLC $104 559 46 265 0,09% Acciones
TWO SIGMA ADVISERS, LP $96 822 59 400 0,08% Acciones
RENAISSANCE TECHNOLOGIES LLC $93 790 41 500 0,08% Acciones
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $89 957 39 804 0,07% Acciones
CITIGROUP INC $86 660 38 345 0,07% Acciones
Frec Markets, Inc. $84 228 37 269 0,07% Acciones
OSAIC HOLDINGS, INC. $82 186 36 366 0,07% Acciones
COMMONWEALTH EQUITY SERVICES, LLC $81 820 36 204 0,07% Acciones
BANK OF MONTREAL /CAN/ $79 095 34 998 0,07% Acciones
Krilogy Financial LLC $78 705 34 825 0,07% Acciones
MORGAN STANLEY $77 462 34 275 0,06% Acciones
Invesco Ltd. $77 181 34 151 0,06% Acciones
Dynamic Technology Lab Private Ltd $74 000 33 000 0,06% Acciones
Vanguard Global Advisers, LLC $73 681 32 602 0,06% Acciones
MERCER GLOBAL ADVISORS INC /ADV $73 111 32 350 0,06% Acciones
AMERICAN CENTURY COMPANIES INC $68 932 30 501 0,06% Acciones
BLAIR WILLIAM & CO/IL $68 295 30 219 0,06% Acciones
EVERGREEN CAPITAL MANAGEMENT LLC $65 540 29 000 0,05% Acciones
CWM, LLC $63 696 39 077 0,05% Acciones
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $61 418 25 275 0,05% Acciones
Nuveen Asset Management, LLC $59 902 12 558 0,05% Acciones
PRUDENTIAL FINANCIAL INC $59 619 26 380 0,05% Acciones
MANUFACTURERS LIFE INSURANCE COMPANY, THE $56 963 25 205 0,05% Acciones
Cerity Partners LLC $53 695 23 759 0,04% Acciones
VANGUARD GROUP INC $53 141 32 602 0,04% Acciones
INTECH INVESTMENT MANAGEMENT LLC $48 486 21 454 0,04% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $45 426 20 100 0,04% Opción de compra
Police & Firemen's Retirement System of New Jersey $43 937 19 441 0,04% Acciones
VOYA INVESTMENT MANAGEMENT LLC $41 948 18 561 0,03% Acciones
Vanguard Personalized Indexing Management, LLC $40 562 17 948 0,03% Acciones
Simplicity Wealth,LLC $39 410 17 438 0,03% Acciones
NEW YORK STATE COMMON RETIREMENT FUND $38 167 16 888 0,03% Acciones
CITADEL ADVISORS LLC $35 708 15 800 0,03% Opción de compra
Creative Planning $35 003 15 488 0,03% Acciones
BNP PARIBAS FINANCIAL MARKETS $34 942 15 461 0,03% Acciones
Navalign, LLC $34 668 15 340 0,03% Acciones
EP Wealth Advisors, LLC $34 526 15 277 0,03% Acciones
China Universal Asset Management Co., Ltd. $32 693 14 466 0,03% Acciones
ProShare Advisors LLC $32 324 14 303 0,03% Acciones
Elmwood Wealth Management, Inc. $28 691 12 695 0,02% Acciones
NORTHERN TRUST CORP $27 992 12 386 0,02% Acciones
OXFORD ASSET MANAGEMENT LLP $27 335 12 095 0,02% Acciones
Graham Capital Management, L.P. $27 287 12 074 0,02% Acciones
Tower Research Capital LLC (TRC) $27 244 12 055 0,02% Acciones
Abel Hall, LLC $26 930 11 916 0,02% Acciones
Caerus Investment Advisors, LLC $26 297 11 636 0,02% Acciones

Informantes de la empresa 40 insiders · 19 directivos · 20 consejeros

Insider Rol Última actividad Acciones en propiedad Compras 12m Ventas 12m Neto 12m
John J Nicols President and CEO 11 de junio de 2018 M 1 072 679 0 0 $0
Peter M Strumph Interim President and CEO 1 de junio de 2012 A 60 756 0 0 $0
Alan Shaw President and CEO 16 de diciembre de 2011 S 202 000 0 0 $0
Georgia Erbez Chief Financial Officer 5 de febrero de 2025 A 76 875 0 0 $0
Sriram Ryali Chief Financial Officer 1 de enero de 2024 A 175 791 0 0 $0
Gordon Sangster SVP & Chief Financial Officer 24 de mayo de 2018 S 153 189 0 0 $0
David D O'Toole SVP & Chief Financial Officer 4 de septiembre de 2013 F 110 687 0 0 $0
Brian Paul Dowd Interim CFO 1 de junio de 2012 A 28 310 0 0 $0
Robert J Lawson SVP and CFO 11 de mayo de 2011 P 44 000 0 0 $0
Kevin Norrett Chief Operating Officer 5 de febrero de 2025 A 177 327 0 0 $0
Alison Moore Chief Technical Officer 5 de febrero de 2025 A 175 571 0 0 $0
Margaret Nell Fitzgerald Chief Legal and Compliance Officer 1 de enero de 2024 A 133 770 0 0 $0
James Lalonde SVP, R&D 17 de julio de 2018 S 195 066 0 0 $0
Michael D. Aldridge Senior Vice President, Corporate & Strategic Development 17 de mayo de 2018 M 0 0 0 $0
Douglas T. Sheehy EVP, Chief Administrative Officer, General Counsel & Secretary 5 de marzo de 2016 F 247 617 0 0 $0
Matthew Tobin SVP, Research & Development 16 de mayo de 2013 M 78 707 0 0 $0
David L. Anton SVP, BioIndustrials 10 de febrero de 2013 F 93 777 0 0 $0
Seufer-Wasserthal Peter SVP, Pharmaceuticals 24 de enero de 2013 A 93 064 0 0 $0
Joseph J. Sarret SVP and CBO 7 de marzo de 2012 A 74 000 0 0 $0
Raymond De Vre Consejero 17 de junio de 2026 A 84 811 0 1 $-6 174
Esther Martinborough Consejero 17 de junio de 2026 A 129 036 0 0 $0
Christos Richards Consejero 17 de junio de 2026 A 85 133 0 0 $0
Cynthia Collins Consejero 17 de junio de 2026 A 112 157 0 0 $0
Stephen George Dilly Consejero 17 de junio de 2026 A 673 053 0 0 $0
Rahul Singhvi Consejero 17 de junio de 2026 A 137 052 0 0 $0
David V Smith Consejero 17 de junio de 2026 A 105 705 0 0 $0
PARKER H STEWART Consejero 17 de junio de 2026 A 143 583 0 0 $0
Dennis P Wolf Consejero 10 de junio de 2025 A 147 903 0 0 $0
Byron L Dorgan Consejero 11 de junio de 2024 A 223 581 0 0 $0
Patrick Y Yang Consejero 19 de julio de 2018 S 304 157 0 0 $0
Kathleen Sereda Glaub Consejero 18 de julio de 2018 S 98 120 0 0 $0
Thomas R Baruch Consejero 26 de junio de 2018 S 153 093 0 0 $0
Bernard J Kelley Consejero 21 de junio de 2018 S 225 668 0 0 $0
Pam P. Cheng Consejero 11 de junio de 2018 A 64 642 0 0 $0
Alexander Karsner Consejero 2 de enero de 2014 A 78 519 0 0 $0
Bruce A Pasternack Consejero 24 de agosto de 2010 P 10 000 0 0 $0
James R Sulat Consejero 27 de abril de 2010 J 5 957 108 0 0 $0
Brazil Holding B.V. Shell Propietario del 10% 31 de mayo de 2011 J 5 573 319 0 0 $0
Equilon Enterprises LLC Propietario del 10% 20 de mayo de 2011 J 5 573 319 0 0 $0
MAXYGEN INC Propietario del 10% 14 de diciembre de 2010 J 524 643 0 0 $0

Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto

Activistas y propietarios del %+ 5 3 tenencias

Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.

Declarante Presentado Participación Estado Propósito Presentación
John Nicols 16 de febrero de 2021 Presentación inicial SEC
– I.RS. IDENTIFICATION NO. OF ABOVE PERSON RAÍZEN ENERGIA S.A., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON SHELL BRAZIL HOLDING B.V., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON ROYAL DUTCH SHELL PLC, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN S.A. INDUSTRIA E COMÉRCIO, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN INVESTIMENTOS E PARTICIPAÇÕES S.A., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN LIMITED ×2 presentaciones 26 de mayo de 2015 Presentación inicial SEC
– I.RS. IDENTIFICATION NO. OF ABOVE PERSON RAIZEN ENERGIA PARTICIPA Ç Õ ES S.A., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON ISPAGNAC PARTICIPA Ç Õ ES LTDA., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON ROYAL DUTCH SHELL PLC, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN S.A. INDUSTRIA E COM É RCIO, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN LIMITED 7 de junio de 2011 Presentación inicial SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Propiedad de ETFs Mantenido por 26 ETFs

El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.

Fondo Ponderación Unidades A fecha de Fuente
QQQS · Invesco Exchange-Traded Fund Trust … 0,26% 40 370 SH 8 de agosto de 2026 Diario
IWC · iShares Trust 0,03% 290 804 SH 8 de agosto de 2026 Diario
BIB · ProShares Trust 0,01% 3 341 NS 31 de mayo de 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0,01% 496 936 SH 8 de agosto de 2026 Diario
VTWG · VANGUARD SCOTTSDALE FUNDS 0,01% 78 444 SH 8 de agosto de 2026 Diario
IBB · iShares Trust 0,01% 613 531 SH 8 de agosto de 2026 Diario
IBBQ · Invesco Exchange-Traded Fund Trust … 0,01% 4 900 SH 8 de agosto de 2026 Diario
RSSL · Global X Funds 0,01% 38 712 NS 30 de abril de 2026 N-PORT
IWO · iShares Trust 0,01% 679 206 SH 8 de agosto de 2026 Diario
ITWO · ProShares Trust 0,01% 4 198 NS 31 de mayo de 2026 N-PORT
IWM · iShares Trust 0,00% 2 240 076 SH 8 de agosto de 2026 Diario
UWM · ProShares Trust 0,00% 3 283 NS 31 de mayo de 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,00% 71 405 SH 8 de agosto de 2026 Diario
AVSC · AMERICAN CENTURY ETF TRUST 0,00% 28 868 NS 31 de mayo de 2026 N-PORT
URTY · ProShares Trust 0,00% 3 320 NS 31 de mayo de 2026 N-PORT
IWN · iShares Trust 0,00% 128 823 SH 8 de agosto de 2026 Diario
HDG · ProShares Trust 0,00% 83 NS 31 de mayo de 2026 N-PORT
DFAS · Dimensional ETF Trust 0,00% 52 788 NS 30 de abril de 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,00% 2 554 NS 31 de mayo de 2026 N-PORT
DCOR · Dimensional ETF Trust 0,00% 1 729 NS 30 de abril de 2026 N-PORT
IWV · iShares Trust 0,00% 16 926 SH 8 de agosto de 2026 Diario
DFAC · Dimensional ETF Trust 0,00% 19 277 NS 30 de abril de 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0,00% 895 869 SH 8 de agosto de 2026 Diario
VTI · VANGUARD INDEX FUNDS 0,00% 2 633 770 SH 8 de agosto de 2026 Diario
VTWV · VANGUARD SCOTTSDALE FUNDS 0,00% 9 454 SH 8 de agosto de 2026 Diario
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 6 744 SH 8 de agosto de 2026 Diario