MBX MBX Biosciences, Inc. - Common Stock
$66,72
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 6, 2026
Rango 52S
$10–$73
91% of range
Calificación del Analista
BUY
15 analysts
Precio Objetivo
$88
+32% upside
P/E (TTM)
-28.0
ROE
-29.6%
Margen de Beneficio Neto
—
MBX Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$66.72
Capitalización Bursátil
$3.00B
P/E (TTM)
-28.0
BPA (TTM)
$-2.38
Ingresos (TTM)
—
Rendimiento div.
—
ROE
-29.6%
Deuda/Capital
—
Rango 52S
$10 – $73
MBX Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-2.38
2023-12-31
→
2025-12-31
Flujo de caja libre
$-82M
2024-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
MBX
Mediana de Pares
P/E (TTM)
-28.0
38.7
P/B (P/C)
8.1
3.8
Price / FCF (Precio / FCF)
-36.6
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
MBX
Mediana de Pares
ROA
-26.6%
-6.4%
ROE
-29.6%
-16.8%
ROIC
-26.6%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
MBX
Mediana de Pares
Current Ratio (Ratio corriente)
24.6
12.8
Quick Ratio (Ratio Rápido)
24.1
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
MBX
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
MBX
Mediana de Pares
MBX Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
15 analistas
- Compra fuerte 5 33,3%
- Compra 9 60,0%
- Mantener 1 6,7%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
10 analistas · 2026-08-18
Mediana
$88.00
← Por Debajo de Todos los Objetivos
$66.72
Mín
$70.00
Máx
$121.00
Objetivo mediano
$88.00
+31,9%
Objetivo medio
$88.40
+32,5%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.06%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.78 | $-0.64 | -0.14% |
| 31 de marzo de 2026 | $-0.51 | $-0.59 | 0.08% |
| 31 de diciembre de 2025 | $-0.49 | $-0.62 | 0.13% |
| 30 de septiembre de 2025 | $-0.63 | $-0.70 | 0.07% |
| 30 de junio de 2025 | $-0.58 | $-0.77 | 0.19% |
| 31 de marzo de 2025 | $-0.71 | $-0.78 | 0.07% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| MBX | $1.42B | -13.3 | — | — | -29.6% | — |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| TARS | $3.48B | -51.5 | 146.7% | -14.7% | -19.7% | — |
| ALMS | — | -3.4 | — | -1011.8% | -61.9% | — |
| SUPN | $2.86B | -73.1 | 8.6% | -5.4% | -3.6% | — |
| ATAI | $223M | -1.4 | -1.9% | -48464.0% | -83.1% | — |
| TRVI | $1.61B | -39.1 | — | — | -22.4% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 12
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| R&D Expense | $79M | $57M | $29M | |
| SG&A Expense | $19M | $11M | $7M | |
| Operating Expenses | $98M | $68M | $35M | |
| Operating Income | $-98M | $-68M | $-35M | |
| Pretax Income | $-87M | $-62M | · | |
| Income Tax | $0 | $0 | $0 | |
| Net Income | $-87M | $-62M | $-33M | |
| EPS (Basic) | $-2.38 | $-5.82 | $-31.96 | |
| EPS (Diluted) | $-2.38 | $-5.82 | $-31.96 | |
| Shares (Basic) | 36,506,092 | 10,642,954 | 1,018,757 | |
| Shares (Diluted) | 36,506,092 | 10,642,954 | 1,018,757 | |
| EBITDA | $-98M | $-68M | · |
Balance general 21
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $75M | $49M | $31M | |
| Short-term Investments | $298M | $213M | $50M | |
| Prepaid Expense | $8M | $5M | $3M | |
| Other Current Assets | $861.0K | $803.0K | $133.0K | |
| Current Assets | $382M | $267M | $83M | |
| PP&E (Net) | $3M | $1M | $439.0K | |
| PP&E (Gross) | $3M | $2M | $617.0K | |
| Accum. Depreciation | $670.0K | $422.0K | $178.0K | |
| Other Non-current Assets | $383.0K | $50.0K | $50.0K | |
| Total Assets | $385M | $269M | $84M | |
| Accounts Payable | $3M | $5M | $1M | |
| Accrued Liabilities | $12M | $6M | $2M | |
| Current Liabilities | $15M | $11M | $4M | |
| Capital Leases | $424.0K | $0 | $171.0K | |
| Total Liabilities | $16M | $11M | $4M | |
| Common Stock | $6.0K | $5.0K | $1.0K | |
| Retained Earnings | $-224M | $-138M | $-76M | |
| AOCI | $286.0K | $55.0K | $60.0K | |
| Stockholders' Equity | $369M | $257M | $-72M | |
| Liabilities + Equity | $385M | $269M | $84M | |
| Shares Outstanding | 44,927,953 | 33,421,525 | 1,257,080 |
Flujo de Efectivo 9
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Stock-based Comp | $9M | $5M | $2M | |
| Operating Cash Flow | $-80M | $-55M | $-32M | |
| CapEx | $2M | $874.0K | $129.0K | |
| Investing Cash Flow | $-84M | $-161M | $-31M | |
| Stock Issued | $602M | · | · | |
| Net Stock Activity | $602M | · | · | |
| Financing Cash Flow | $190M | $234M | $69M | |
| Net Change in Cash | $26M | $19M | $6M | |
| Free Cash Flow | $-82M | $-56M | · |
Rentabilidad 3
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| ROA | -26.6% | -35.1% | · | |
| ROE | -29.6% | -23.4% | · | |
| ROIC | -26.6% | · | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 24.6 | 24.2 | · | |
| Quick Ratio | 24.1 | 23.7 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Net Income TTM | $-87M | $-62M | · | |
| Market Cap | $1.42B | $616M | · | |
| P/E | -13.3 | -3.2 | · | |
| P/B | 3.8 | 2.4 | · | |
| P / Tangible Book | 3.8 | 2.4 | · | |
| P / Cash Flow | -17.7 | -11.3 | · | |
| P / FCF | -17.3 | -11.1 | · | |
| Earnings Yield | -7.5% | -31.6% | · |
Estado de resultados 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $31M | $18M | $20M | $19M | $18M | $22M | $15M | $17M | $8M | |
| SG&A Expense | $10M | $9M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Operating Expenses | $41M | $27M | $26M | $24M | $22M | $27M | $19M | $20M | $10M | |
| Operating Income | $-41M | $-27M | $-26M | $-24M | $-22M | $-27M | $-19M | $-20M | $-10M | |
| Net Income | $-37M | $-24M | $-22M | $-22M | $-19M | $-24M | $-16M | $-18M | $-9M | |
| EPS (Basic) | $-0.78 | $-0.50 | $-0.46 | $-0.63 | $-0.58 | $-0.71 | $19.84 | $-2.78 | $-7.68 | |
| EPS (Diluted) | $-0.78 | $-0.50 | $-0.46 | $-0.63 | $-0.58 | $-0.71 | $19.84 | $-2.78 | $-7.68 | |
| Shares (Basic) | 47,696,363 | 46,576,204 | -64,551,276 | 34,198,597 | 33,446,385 | 33,412,386 | 1,668,393 | 6,515,616 | 41,933 | |
| Shares (Diluted) | 47,696,363 | 46,576,204 | -64,551,276 | 34,198,597 | 33,446,385 | 33,412,386 | 1,668,393 | 6,515,616 | 41,933 | |
| EBITDA | $-41M | $-27M | · | $-24M | $-22M | $-27M | · | $-20M | · |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $54M | $45M | $75M | $223M | $40M | $30M | $49M | $133M | $31M | |
| Short-term Investments | $364M | $395M | $298M | $169M | $185M | $211M | $213M | $144M | $50M | |
| Prepaid Expense | $9M | $9M | $8M | $6M | $4M | $3M | $5M | $4M | $3M | |
| Other Current Assets | $1M | $814.0K | $861.0K | $882.0K | $472.0K | $626.0K | $803.0K | $838.0K | $133.0K | |
| Current Assets | $428M | $449M | $382M | $398M | $229M | $244M | $267M | $281M | $83M | |
| PP&E (Net) | $5M | $3M | $3M | $2M | $2M | $2M | $1M | $1M | $439.0K | |
| PP&E (Gross) | $5M | $4M | $3M | $3M | $2M | $2M | $2M | $1M | $617.0K | |
| Accum. Depreciation | $813.0K | $734.0K | $670.0K | $610.0K | $560.0K | $499.0K | $422.0K | $364.0K | $178.0K | |
| Other Non-current Assets | $625.0K | $579.0K | $383.0K | $50.0K | $50.0K | $50.0K | $50.0K | $50.0K | $50.0K | |
| Total Assets | $436M | $453M | $385M | $400M | $232M | $246M | $269M | $282M | $84M | |
| Accounts Payable | $4M | $7M | $3M | $4M | $6M | $4M | $5M | $5M | $1M | |
| Accrued Liabilities | $19M | $7M | $12M | $8M | $6M | $6M | $6M | $6M | $2M | |
| Current Liabilities | $24M | $15M | $15M | $12M | $12M | $10M | $11M | $11M | $4M | |
| Capital Leases | $3M | $377.0K | $424.0K | $469.0K | $512.0K | · | $0 | $44.0K | $171.0K | |
| Total Liabilities | $26M | $15M | $16M | $13M | $12M | $11M | $11M | $11M | $4M | |
| Common Stock | $6.0K | $6.0K | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $1.0K | |
| Retained Earnings | $-285M | $-248M | $-224M | $-202M | $-181M | $-161M | $-138M | $-122M | $-76M | |
| AOCI | $-1M | $-606.0K | $286.0K | $154.0K | $11.0K | $53.0K | $55.0K | $106.0K | $60.0K | |
| Stockholders' Equity | $410M | $438M | $369M | $388M | $219M | $235M | $257M | $271M | $-72M | |
| Liabilities + Equity | $436M | $453M | $385M | $400M | $232M | $246M | $269M | $282M | $84M | |
| Shares Outstanding | 47,949,804 | 47,570,464 | 44,927,953 | 44,715,498 | 33,592,226 | 33,424,371 | 33,421,525 | 33,376,058 | 1,257,080 |
Flujo de Efectivo 9
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $6M | $5M | $3M | $2M | $2M | $2M | $1M | $1M | $1M | |
| Operating Cash Flow | $-23M | $-20M | $-18M | $-22M | $-17M | $-23M | $-16M | $-15M | $-11M | |
| CapEx | $901.0K | $437.0K | $793.0K | $399.0K | $707.0K | $30.0K | $92.0K | $57.0K | $55.0K | |
| Investing Cash Flow | $29M | $-97M | $-130M | $17M | $26M | $3M | $-67M | $-101M | $-29M | |
| Stock Issued | $0 | $689M | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $689M | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $87M | $438.0K | $188M | $1M | $4.0K | $-132.0K | $236M | $19.0K | |
| Net Change in Cash | $9M | $-30M | $-148M | $183M | $10M | $-19M | $-84M | $120M | $-40M | |
| Free Cash Flow | · | $-21M | · | · | · | $-23M | · | · | · |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -11.1% | -6.7% | · | -6.3% | -16.8% | -19.4% | · | -12.8% | · | |
| ROE | -11.8% | -7.0% | · | -6.6% | -17.7% | -20.3% | · | -13.4% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 18.1 | 30.8 | · | 33.0 | 19.5 | 23.3 | · | 25.7 | · | |
| Quick Ratio | 17.7 | 30.2 | · | 32.5 | 19.1 | 23.0 | · | 25.4 | · |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-102M | $-88M | · | $-83M | $-77M | $-70M | · | $-56M | · | |
| Market Cap | $2.65B | $1.42B | · | $783M | $383M | $247M | · | $867M | · | |
| P/E | -22.2 | -12.3 | · | -3.7 | -0.7 | -0.3 | · | -0.7 | · | |
| P/B | 6.5 | 3.2 | · | 2.0 | 1.7 | 1.0 | · | 3.2 | · | |
| P / Tangible Book | 6.5 | 3.2 | · | 2.0 | 1.7 | 1.0 | · | 3.2 | · | |
| P / Cash Flow | · | -70.3 | · | · | · | -10.9 | · | · | · | |
| P / FCF | · | -68.8 | · | · | · | -10.9 | · | · | · | |
| Earnings Yield | -4.5% | -8.1% | · | -26.9% | -146.3% | -357.3% | · | -134.9% | · |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Beneficio neto | $-87M | $-62M | $-33M |
| EPS Diluido | $-2.38 | $-5.82 | $-31.96 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Ratio corriente | 24.6 | 24.2 | — |
| Ratio Rápido | 24.1 | 23.7 | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Flujo de caja libre | $-82M | $-56M | — |
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Propietarios institucionales (13F) 182 declarantes · $2.7B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 47 (+14 vs trimestre anterior) | 18 (-1 vs trimestre anterior) | 59 (+20 vs trimestre anterior) | 47 (-3 vs trimestre anterior) | +4.5M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $367 191 118 | 6 652 013 | 13,63% | Acciones |
| FMR LLC | $268 545 074 | 4 864 947 | 9,97% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $218 738 501 | 3 962 654 | 8,12% | Acciones |
| NEA Management Company, LLC | $199 519 627 | 3 614 486 | 7,41% | Acciones |
| ORBIMED ADVISORS LLC | $189 266 227 | 3 428 736 | 7,03% | Acciones |
| Paradigm Biocapital Advisors LP | $138 442 428 | 2 508 015 | 5,14% | Acciones |
| NVP ASSOCIATES, LLC | $117 925 692 | 2 136 335 | 4,38% | Acciones |
| Deep Track Capital, LP | $95 637 809 | 1 732 569 | 3,55% | Acciones |
| Polar Capital Holdings Plc | $88 789 973 | 1 608 514 | 3,30% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $81 551 818 | 1 477 388 | 3,03% | Acciones |
| Aaron Wealth Advisors LLC | $64 462 505 | 1 167 799 | 2,39% | Acciones |
| Driehaus Capital Management LLC | $58 323 161 | 1 056 579 | 2,17% | Acciones |
| Kynam Capital Management, LP | $51 600 905 | 934 799 | 1,92% | Acciones |
| Woodline Partners LP | $49 685 078 | 900 092 | 1,84% | Acciones |
| EVENTIDE ASSET MANAGEMENT, LLC | $48 216 758 | 873 492 | 1,79% | Acciones |
| STATE STREET CORP | $47 718 523 | 864 466 | 1,77% | Acciones |
| Parkman Healthcare Partners LLC | $44 169 550 | 800 173 | 1,64% | Acciones |
| BRAIDWELL LP | $39 240 576 | 710 880 | 1,46% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $36 875 889 | 667 870 | 1,37% | Acciones |
| TCG Crossover Management, LLC | $35 880 000 | 650 000 | 1,33% | Acciones |
| Cormorant Asset Management, LP | $30 360 000 | 550 000 | 1,13% | Acciones |
| Soleus Capital Management, L.P. | $28 443 401 | 515 279 | 1,06% | Acciones |
| MARSHALL WACE, LLP | $22 184 052 | 401 885 | 0,82% | Acciones |
| EcoR1 Capital, LLC | $21 445 200 | 388 500 | 0,80% | Acciones |
| GOLDMAN SACHS GROUP INC | $21 151 812 | 383 185 | 0,79% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $19 138 778 | 346 717 | 0,71% | Acciones |
| Rock Springs Capital Management LP | $16 461 634 | 298 218 | 0,61% | Acciones |
| Candriam S.C.A. | $15 986 698 | 289 893 | 0,59% | Acciones |
| BANK OF AMERICA CORP /DE/ | $15 871 325 | 287 524 | 0,59% | Acciones |
| Opaleye Management Inc. | $14 352 000 | 260 000 | 0,53% | Acciones |
| Schonfeld Strategic Advisors LLC | $13 726 583 | 248 670 | 0,51% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $12 866 844 | 233 095 | 0,48% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $12 527 364 | 226 945 | 0,47% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $12 483 535 | 226 151 | 0,46% | Acciones |
| Tetragon Partners GP Ltd | $11 235 574 | 203 543 | 0,42% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $11 118 881 | 201 429 | 0,41% | Acciones |
| Caption Management, LLC | $11 040 000 | 200 000 | 0,41% | Opción de compra |
| Caption Management, LLC | $11 040 000 | 200 000 | 0,41% | Opción de venta |
| Caligan Partners LP | $11 040 000 | 200 000 | 0,41% | Acciones |
| D. E. Shaw & Co., Inc. | $10 088 738 | 182 767 | 0,37% | Acciones |
| KVP Capital Advisors, LP | $6 708 125 | 121 524 | 0,25% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $6 263 820 | 113 475 | 0,23% | Acciones |
| Burkehill Global Management, LP | $5 520 000 | 100 000 | 0,20% | Acciones |
| TD Asset Management Inc | $5 277 010 | 95 598 | 0,20% | Acciones |
| VANGUARD GROUP INC | $5 248 193 | 166 398 | 0,19% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5 210 880 | 94 400 | 0,19% | Opción de compra |
| Elmind Capital, LP | $5 023 200 | 91 000 | 0,19% | Acciones |
| BARCLAYS PLC | $4 755 424 | 86 149 | 0,18% | Acciones |
| Affinity Asset Advisors, LLC | $4 140 000 | 75 000 | 0,15% | Acciones |
| PFM Health Sciences, LP | $3 917 599 | 70 971 | 0,15% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $3 883 486 | 70 353 | 0,14% | Acciones |
| PRUDENTIAL FINANCIAL INC | $3 684 324 | 66 745 | 0,14% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $3 649 382 | 66 112 | 0,14% | Acciones |
| MOORE CAPITAL MANAGEMENT, LP | $3 582 094 | 64 893 | 0,13% | Acciones |
| Rhenman & Partners Asset Management AB | $3 422 400 | 62 000 | 0,13% | Acciones |
| BlackRock, Inc. | $2 806 534 | 50 843 | 0,10% | Acciones |
| ALPS ADVISORS INC | $2 650 262 | 48 012 | 0,10% | Acciones |
| PLATINUM INVESTMENT MANAGEMENT LTD | $2 406 554 | 43 597 | 0,09% | Acciones |
| Swiss National Bank | $2 368 080 | 42 900 | 0,09% | Acciones |
| Ensign Peak Advisors, Inc | $2 327 011 | 42 156 | 0,09% | Acciones |
| ALGERT GLOBAL LLC | $2 322 264 | 42 070 | 0,09% | Acciones |
| JANE STREET GROUP, LLC | $2 075 520 | 37 600 | 0,08% | Opción de compra |
| RHUMBLINE ADVISERS | $2 053 213 | 37 196 | 0,08% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 711 200 | 31 000 | 0,06% | Opción de venta |
| Bank of New York Mellon Corp | $1 627 958 | 29 492 | 0,06% | Acciones |
| WELLS FARGO & COMPANY/MN | $1 562 878 | 28 313 | 0,06% | Acciones |
| EXCHANGE TRADED CONCEPTS, LLC | $1 513 639 | 27 421 | 0,06% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 472 957 | 26 684 | 0,05% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $1 424 160 | 25 800 | 0,05% | Acciones |
| CITIGROUP INC | $1 287 871 | 23 331 | 0,05% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $1 251 936 | 22 680 | 0,05% | Acciones |
| CITADEL ADVISORS LLC | $1 236 480 | 22 400 | 0,05% | Opción de compra |
| AQR CAPITAL MANAGEMENT LLC | $1 215 007 | 22 011 | 0,05% | Acciones |
| Cerity Partners LLC | $1 149 374 | 20 822 | 0,04% | Acciones |
| Vanguard Global Advisers, LLC | $1 047 089 | 18 969 | 0,04% | Acciones |
| MetLife Investment Management, LLC | $1 007 400 | 18 250 | 0,04% | Acciones |
| Koa Wealth Management, LLC | $944 638 | 17 113 | 0,04% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $925 350 | 31 000 | 0,03% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $881 599 | 15 971 | 0,03% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $814 310 | 14 752 | 0,03% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $788 918 | 14 292 | 0,03% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $679 535 | 22 765 | 0,03% | Acciones |
| Invesco Ltd. | $679 015 | 12 301 | 0,03% | Acciones |
| DAFNA Capital Management LLC | $651 857 | 11 809 | 0,02% | Acciones |
| HighVista Strategies LLC | $642 197 | 11 634 | 0,02% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $607 200 | 11 000 | 0,02% | Acciones |
| FRED ALGER MANAGEMENT, LLC | $545 210 | 9 877 | 0,02% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $544 272 | 9 860 | 0,02% | Acciones |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $539 690 | 9 777 | 0,02% | Acciones |
| Virtus Investment Advisers, LLC | $508 668 | 9 215 | 0,02% | Acciones |
| China Universal Asset Management Co., Ltd. | $506 460 | 9 175 | 0,02% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $505 301 | 9 154 | 0,02% | Acciones |
| PROFUND ADVISORS LLC | $486 422 | 8 812 | 0,02% | Acciones |
| ACT CAPITAL MANAGEMENT, LLC | $441 600 | 8 000 | 0,02% | Acciones |
| Optimize Financial Inc | $433 064 | 14 508 | 0,02% | Acciones |
| DNB Asset Management AS | $430 174 | 7 793 | 0,02% | Acciones |
| AXQ CAPITAL, LP | $428 186 | 7 757 | 0,02% | Acciones |
| State of New Jersey Common Pension Fund D | $381 598 | 6 913 | 0,01% | Acciones |
| Quantinno Capital Management LP | $358 634 | 6 497 | 0,01% | Acciones |
| Rafferty Asset Management, LLC | $353 832 | 6 410 | 0,01% | Acciones |
Informantes de la empresa 22 insiders · 4 directivos · 10 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Steven L. Hoerter | President and CEO | 3 de agosto de 2026 A | 82 938 | 1 | 0 | $265 000 |
| Kent P. Hawryluk | President & CEO | 6 de mayo de 2026 S | 727 667 | 2 | 1 | $780 454 |
| John W Smither | Chief Financial Officer | 3 de agosto de 2026 A | 28 000 | 0 | 0 | $0 |
| Richard Bartram | Chief Financial Officer | 2 de febrero de 2026 A | 15 000 | 0 | 0 | $0 |
| Steven Ryder | Consejero | 4 de junio de 2026 A | — | 0 | 0 | $0 |
| Tiba Aynechi | Consejero | 4 de junio de 2026 A | 2 136 335 | 0 | 0 | $0 |
| Laurie Stelzer | Consejero | 4 de junio de 2026 A | — | 0 | 0 | $0 |
| Ora H. Pescovitz | Consejero | 4 de junio de 2026 A | 24 329 | 0 | 0 | $0 |
| Patrick J. Heron | Consejero | 4 de junio de 2026 A | 4 552 774 | 0 | 0 | $0 |
| Edward T. Mathers | Consejero | 4 de junio de 2026 A | 3 614 486 | 0 | 0 | $0 |
| James M Cornelius | Consejero | 5 de junio de 2025 A | 102 082 | 0 | 0 | $0 |
| GORDON CARL L | Consejero | 18 de febrero de 2025 P | 747 887 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | Propietario del 10% | 16 de septiembre de 2024 C | 1 790 122 | 0 | 0 | $0 |
| Rick Yang | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Carmen Chang | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Mohamad Makhzoumi | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Ali Behbahani | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Anthony A. Florence, Jr. | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Paul Walker | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Forest Baskett | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Scott D. Sandell | Propietario del 10% | 16 de septiembre de 2024 C | 3 614 486 | 0 | 0 | $0 |
| Salomon Azoulay | — | 4 de agosto de 2026 S | 14 399 | 0 | 4 | $-2 716 674 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 4 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P., FHMLSP, L.L.C., Frazier Life Sciences X, L.P., FHMLS X, L.P., FHMLS X, L.L.C., Frazier Life Sciences XI, L.P., FHMLS XI, L.P., FHMLS XI, L.L.C., James N. Topper, Patrick J. Heron ×4 presentaciones | 10 de agosto de 2026 | 11,70% | Enmienda | — | SEC |
| ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP VII LLC, ORBIMED GENESIS GP LLC ×4 presentaciones | 10 de agosto de 2026 | 6,40% | Enmienda | — | SEC |
| New Enterprise Associates 17, L.P., NEA Partners 17, L.P., NEA 17 GP, LLC, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad H. Makhzoumi, Edward T. Mathers, Scott D. Sandell, Paul Walker, Rick Yang ×2 presentaciones | 10 de noviembre de 2025 | 8,10% | Enmienda | Inversión pasiva | SEC |
| Norwest Venture Partners XVI, LP, Genesis VC Partners XVI, LLC, NVP Associates, LLC, Jeffrey Crowe, Jon Erik Kossow, Tiba Aynechi ×2 presentaciones | 30 de septiembre de 2025 | 4,80% | Enmienda | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 45 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| PTH · Invesco Exchange-Traded Fund Trust | 1,52% | 55 186 SH | 8 de agosto de 2026 | Diario |
| PILL · Direxion Shares ETF Trust | 1,37% | 5 866 NS | 30 de abril de 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 0,90% | 46 286 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,75% | 9 242 NS | 30 de abril de 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,53% | 8 761 NS | 31 de mayo de 2026 | N-PORT |
| IWC · iShares Trust | 0,47% | 105 329 SH | 8 de agosto de 2026 | Diario |
| IHE · iShares Trust | 0,39% | 95 133 SH | 8 de agosto de 2026 | Diario |
| FMED · Fidelity Covington Trust | 0,39% | 5 128 NS | 31 de mayo de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,22% | 2 591 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,19% | 67 904 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,15% | 216 559 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,13% | 281 995 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,10% | 33 276 SH | 8 de agosto de 2026 | Diario |
| FFSM · FIDELITY COVINGTON TRUST | 0,08% | 36 306 NS | 30 de abril de 2026 | N-PORT |
| BIB · ProShares Trust | 0,07% | 1 658 NS | 31 de mayo de 2026 | N-PORT |
| IWM · iShares Trust | 0,07% | 784 502 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,05% | 178 613 SH | 8 de agosto de 2026 | Diario |
| ISCV · iShares Trust | 0,03% | 3 348 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,03% | 12 353 NS | 30 de abril de 2026 | N-PORT |
| ISCB · iShares Trust | 0,03% | 1 098 SH | 8 de agosto de 2026 | Diario |
| GSSC · Goldman Sachs ETF Trust | 0,02% | 7 648 NS | 31 de mayo de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 1 340 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,02% | 305 918 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,02% | 64 357 SH | 8 de agosto de 2026 | Diario |
| ISCG · iShares Trust | 0,02% | 2 970 SH | 8 de agosto de 2026 | Diario |
| SCHA · SCHWAB STRATEGIC TRUST | 0,02% | 119 833 NS | 31 de mayo de 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 1 376 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,01% | 1 048 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 10 305 NS | 30 de abril de 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 1 060 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,01% | 40 965 NS | 30 de abril de 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 5 970 NS | 31 de mayo de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 1 397 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 14 062 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 27 NS | 31 de mayo de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 41 133 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 7 686 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 15 071 NS | 31 de mayo de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 5 577 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 8 774 NS | 30 de abril de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 344 NS | 30 de abril de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 869 NS | 30 de abril de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 135 725 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 2 567 SH | 8 de agosto de 2026 | Diario |
| DFSU · Dimensional ETF Trust | 0,00% | 29 NS | 30 de abril de 2026 | N-PORT |