NKTR Nektar Therapeutics - Common Stock

NASDAQ · Pharmaceuticals · Ver en SEC EDGAR ↗
$75,92
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 14, 2026

Acerca de Nektar Therapeutics - Common Stock Descripción general de la empresa de Wikipedia

Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, etc. The company developed the world's first inhalable non-injectable insulin, Exubera, which was awarded as the bronze award by Wall Street Journal for its technological breakthrough.

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Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, etc. The company developed the world's first inhalable non-injectable insulin, Exubera, which was awarded as the bronze award by Wall Street Journal for its technological breakthrough.

Background

The company is engaged in developing a proprietary pipeline of drug candidates for several therapeutic areas including oncology, pain, anti-infectives, anti-viral and immunology. The company's research and development involve in small molecule and biologic drug candidates. Its drug candidate base consists of naloxegol (Movantik), a Phase III oral opioid antagonist, etirinotecan pegol, a topoisomerase inhibitor under Phase III clinical study as of 2012, NKTR 061, NKTR-181, NKTR-214, etc.

In 2013, the company was assigned a patent which was developed by the company and other four co-inventors. The products of the company is served as a supplement to improve the pharmacokinetics, pharmacodynamics, half-life, bioavailability and other areas of drugs for the patients worldwide. As of March 2014, the company had a market capitalization of $1.7 billion with an enterprise value of $1.67 billion.

As of December 2024, at a stock price-per-share of roughly $1, the market cap is roughly $171 million. Nektar underwent periods of downsizing after unsuccessful partnerships were ended with Eli Lilly in 2023 and Bristol Myers Squibb in 2022, resulting in layoffs of most company employees.

Pipeline

Etirinotecan pegol was in the phase III BEACON trial as well as in the I-SPY2 adaptive clinical trial for breast cancer in 2016. The European Medicines Agency refused a marketing authorisation in 2017.

Bempegaldesleukin (NKTR-214) is a CD122-biased immune-stimulatory cytokine, Phase I results were announced in November 2016. It is now in a phase 2 trial in combination with nivolumab for various advanced cancers.

In 2023 Nektar's partnership with Eli Lilly in development of "rezpeg" was ended. Eli Lilly claimed the drug lacked suitable efficacy, while Nektar responded that Eli Lilly had botched the analysis.

Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗

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NKTR Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas

Precio
$75.92
Capitalización Bursátil
$2.24B
P/E (TTM)
-11.3
BPA (TTM)
$-9.73
Ingresos (TTM)
$55M
Rendimiento div.
ROE
-500.1%
Deuda/Capital
Rango 52S
$25 – $109

NKTR Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista

Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA

Ingresos y Beneficio Neto $55M
10-point trend, -66.6%
2016-12-31 2025-12-31
BPA $-9.73
10-point trend, -784.5%
2016-12-31 2025-12-31
Flujo de caja libre $-209M
10-point trend, -69.1%
2016-12-31 2025-12-31
Márgenes -297.1%

Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?

Métrica
Tendencia a 5 años
NKTR
Mediana de Pares
P/E (TTM)
5-point trend, +93.9%
-11.3
29.4
P/S (TTM) (P/V (TTM))
5-point trend, -95.8%
40.5
4.9
P/B (P/C)
5-point trend, -82.7%
24.9
6.5
Price / FCF (Precio / FCF)
5-point trend, +95.3%
-10.7

Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC

Métrica
Tendencia a 5 años
NKTR
Mediana de Pares
Operating Margin (Margen Operativo)
5-point trend, +42.1%
-253.7%
Net Profit Margin (Margen de Beneficio Neto)
5-point trend, +42.2%
-297.1%
-9.0%
ROA
5-point trend, -42.4%
-56.2%
-8.2%
ROE
5-point trend, -606.9%
-500.1%
-19.4%
ROIC
5-point trend, -137.1%
-155.8%

Salud financiera Deuda, liquidez, solvencia — solidez del balance general

Métrica
Tendencia a 5 años
NKTR
Mediana de Pares
Current Ratio (Ratio corriente)
5-point trend, -46.7%
5.0
3.6
Quick Ratio (Ratio Rápido)
5-point trend, -49.6%
0.3

Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años

Métrica
Tendencia a 5 años
NKTR
Mediana de Pares
Revenue YoY (Ingresos interanuales)
5-point trend, -45.8%
-43.9%
Revenue CAGR 3Y (Ingresos CAGR 3A)
5-point trend, -45.8%
-15.7%
Revenue CAGR 5Y (Ingresos CAGR 5A)
5-point trend, -45.8%
-18.4%

Métricas por acción BPA, valor contable por acción, flujo de caja por acción, dividendo por acción

Métrica
Tendencia a 5 años
NKTR
Mediana de Pares
EPS (Diluted) (BPA (Diluido))
5-point trend, -240.2%
$-9.73

Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar

Métrica
Tendencia a 5 años
NKTR
Mediana de Pares

NKTR Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista

COMPRA 17 analistas
  • Compra fuerte 7 41,2%
  • Compra 8 47,1%
  • Mantener 2 11,8%
  • Venta 0 0,0%
  • Venta fuerte 0 0,0%

Precio objetivo a 12 meses

9 analistas · 2026-08-16
Objetivo mediano $151.00 +98,9%
Objetivo medio $153.22 +101,8%

Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados

Sorpresa Media
0.21%
Período EPS Actual EPS est. Sorpresa
30 de junio de 2026 $-1.23 $-2.02 0.79%
31 de marzo de 2026 $-1.82 $-1.63 -0.19%
31 de diciembre de 2025 $-1.78 $-2.52 0.74%
30 de septiembre de 2025 $-1.87 $-2.74 0.87%
30 de junio de 2025 $-2.95 $-3.10 0.15%
31 de marzo de 2025 $-3.60 $-2.51 -1.1%

Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector

Ticker Capitalización Bursátil P/E Ingresos interanuales Margen Neto ROE Margen Bruto
NKTR $862M -4.3 -43.9% -297.1% -500.1%
ALMS -3.4 -1011.8% -61.9%
TARS $3.48B -51.5 146.7% -14.7% -19.7%
SUPN $2.86B -73.1 8.6% -5.4% -3.6%
ATAI $223M -1.4 -1.9% -48464.0% -83.1%
TRVI $1.61B -39.1 -22.4%
AMRX 57.3 8.1% 2.4% -80.0% 36.9%
AMLX $1.33B -7.9 -77.1% -61.2%
PBH $3.33B 15.2 -4.3% 17.5% 10.2% 54.7%
RAPP $1.45B -10.6 -29.8%
OCUL $2.62B -8.5 -18.5% -511.9% -55.4%

Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja

Estado de resultados 17
Datos anuales de Estado de resultados para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue 12-point trend, -72.5% $55M $98M $90M $92M $102M $153M $115M $1.19B $308M $165M $231M $201M
Cost of Revenue 12-point trend, -100.0% $0 $31M $34M $22M $25M $19M $21M $24M $31M $30M $34M $29M
R&D Expense 12-point trend, -20.6% $117M $121M $114M $218M $400M $409M $435M $400M $268M $204M $183M $148M
SG&A Expense 12-point trend, +67.8% $69M $77M $77M $92M $123M $105M $99M $81M $52M $44M $43M $41M
Operating Expenses 12-point trend, -10.1% $195M $204M $354M $468M $548M $578M $555M $505M $367M $278M $260M $217M
Operating Income 12-point trend, -749.9% $-140M $-105M $-264M $-376M $-446M $-425M $-440M $688M $-60M $-113M $-29M $-16M
Interest Expense 9-point trend, -100.0% · · · $0 $0 $7M $21M $22M $22M $22M $18M $18M
Interest Income 5-point trend, +282.2% $10M $14M $19M $7M $3M · · · · · · ·
Other Non-op 12-point trend, -55.7% $361.0K $-390.0K $-6M $-116.0K $-162.0K $18M $46M $38M $5M $2M $2M $814.0K
Pretax Income 12-point trend, -201.7% $-164M $-119M $-276M $-365M $-523M $-444M $-440M $683M $-96M $-153M $-81M $-54M
Income Tax 12-point trend, +73.0% $-138.0K $-239.0K $-200.0K $3M $557.0K $493.0K $613.0K $1M $616.0K $876.0K $506.0K $-512.0K
Net Income 12-point trend, -204.3% $-164M $-119M $-276M $-368M $-524M $-444M $-441M $681M $-97M $-154M $-81M $-54M
EPS (Basic) 10-point trend, -784.5% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $4.02 $-0.62 $-1.10 · ·
EPS (Diluted) 10-point trend, -784.5% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $3.78 $-0.62 $-1.10 · ·
Shares (Basic) 10-point trend, -87.9% 16,870,930 13,710,775 190,001,000 187,138,000 183,298,000 178,581,000 174,993,000 169,600,000 155,953,000 139,596,000 · ·
Shares (Diluted) 10-point trend, -87.9% 16,870,930 13,710,775 190,001,000 187,138,000 183,298,000 178,581,000 174,993,000 180,119,000 155,953,000 139,596,000 · ·
EBITDA 11-point trend, -377.0% $-140M $-101M $-257M $-364M $-433M $-413M $-429M $697M $-47M $-113M $-29M ·
Balance general 24
Datos anuales de Balance general para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +22.2% $15M $44M $35M $88M $25M $199M $96M $195M $5M $60M $56M $12M
Short-term Investments 4-point trend, +29.2% · · · · · · · · $291M $329M $253M $225M
Receivables 11-point trend, -100.0% · $0 $1M $6M $22M $39M $37M $43M $5M $16M $20M $4M
Inventory 12-point trend, -100.0% $0 $0 $16M $19M $16M $15M $13M $11M $11M $11M $11M $13M
Other Current Assets 12-point trend, +132.7% $21M $6M $10M $16M $23M $22M $15M $21M $8M $10M $10M $9M
Current Assets 12-point trend, -7.6% $266M $261M $331M $546M $796M $1.14B $1.42B $1.44B $327M $426M $350M $288M
PP&E (Net) 12-point trend, -97.1% $2M $3M $19M $32M $61M $60M $66M $49M $47M $66M $71M $70M
Accum. Depreciation 11-point trend, -83.0% · $16M $87M $125M $148M $138M $128M $121M $115M $111M $103M $94M
Goodwill 10-point trend, -100.0% · · $0 $77M $77M $77M $77M $77M $77M $77M $77M $77M
Other Non-current Assets 12-point trend, +115.8% $14M $5M $5M $2M $3M $1M $344.0K $4M $994.0K $817.0K $754.0K $7M
Total Assets 12-point trend, -36.5% $280M $304M $398M $711M $1.12B $1.54B $1.98B $2.15B $509M $569M $499M $442M
Accounts Payable 12-point trend, +298.4% $11M $12M $10M $13M $10M $22M $19M $6M $5M $3M $2M $3M
Accrued Liabilities 5-point trend, +247.0% $22M $30M $22M $37M · · · · · · · $6M
Current Liabilities 12-point trend, -16.4% $54M $61M $51M $68M $85M $116M $354M $82M $56M $72M $61M $64M
Capital Leases 11-point trend, +1476.6% $65M $83M $99M $113M $126M $136M $143M $0 · $2M $1M $4M
Other Non-current Liabilities 12-point trend, -41.4% $9M $7M $5M $8M $4M $9M $768.0K $10M $6M $7M $10M $15M
Total Liabilities 12-point trend, -53.0% $191M $243M $267M $344M $438M $461M $572M $433M $421M $481M $492M $405M
Common Stock 12-point trend, -84.6% $2.0K $1.0K $19.0K $19.0K $19.0K $18.0K $17.0K $17.0K $15.0K $15.0K $13.0K $13.0K
Retained Earnings 12-point trend, -110.5% $-3.76B $-3.60B $-3.48B $-3.20B $-2.83B $-2.31B $-1.86B $-1.42B $-2.12B $-2.02B $-1.87B $-1.79B
Treasury Stock 2-point trend, +3000000.00 · $3M $0 · · · · · · · · ·
AOCI 12-point trend, +101.1% $17.0K $61.0K $80.0K $-7M $-4M $-2M $-1M $-6M $-2M $-2M $-2M $-2M
Stockholders' Equity 12-point trend, +147.3% $90M $61M $131M $367M $680M $1.08B $1.41B $1.72B $88M $88M $6M $36M
Liabilities + Equity 12-point trend, -36.5% $280M $304M $398M $711M $1.12B $1.54B $1.98B $2.15B $509M $569M $499M $442M
Shares Outstanding 12-point trend, -84.5% 20,378,832 12,385,001 12,757,984 188,560,000 185,468,000 180,091,000 176,505,000 173,530,000 159,524,000 153,212,000 135,289,000 131,216,000
Flujo de Efectivo 14
Datos anuales de Flujo de Efectivo para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
D&A 12-point trend, -92.1% $1M $4M $7M $12M $13M $12M $11M $9M $13M $13M $11M $13M
Stock-based Comp · · · · · · · · · · · $17M
Deferred Tax 12-point trend, +306.5% $64.0K $-10.0K $-140.0K $3M $-102.0K $-36.0K $-21.0K $93.0K $35.0K $-115.0K $-22.0K $-31.0K
Other Non-cash 8-point trend, -1770.0% · $-61M $77M $49M $98M $119M $101M $28M $4M · · ·
Operating Cash Flow 12-point trend, -46.8% $-209M $-176M $-193M $-304M $-413M $-313M $-329M $718M $-80M $-117M $-73M $-142M
CapEx 12-point trend, -98.3% $171.0K $1M $865.0K $6M $15M $7M $26M $14M $10M $6M $11M $10M
Investing Cash Flow 10-point trend, +98.5% $-1M $143M $140M $366M $203M $496M $207M $-1.38B $-29M $-82M · ·
Stock Repurchased 3-point trend, +0.00 $0 $3M $0 · · · · · · · · ·
Net Stock Activity 2-point trend, +100.0% $0 $-3M · · · · · · · · · ·
Financing Cash Flow 10-point trend, -11.3% $181M $42M $30.0K $2M $36M $-80M $23M $852M $54M $204M · ·
Net Change in Cash 12-point trend, -9.1% $-29M $9M $-53M $63M $-174M $103M $-99M $190M $-55M $4M $43M $-27M
Taxes Paid 12-point trend, -120.2% $-195.0K $76.0K $3M $272.0K $325.0K $539.0K $555.0K $618.0K $556.0K $757.0K $860.0K $964.0K
Free Cash Flow 11-point trend, -147.6% $-209M $-177M $-193M $-310M $-428M $-321M $-355M $704M $-90M $-123M $-84M ·
Levered FCF 8-point trend, -201.6% · · · $-310M $-428M $-327M $-376M $682M $-112M $-146M $-103M ·
Rentabilidad 7
Datos anuales de Rentabilidad para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, -1892.6% -253.7% -106.9% -292.6% -408.6% -437.8% -278.0% -383.9% 57.6% -19.4% -68.2% -12.7% ·
Net Margin 11-point trend, -744.7% -297.1% -120.9% -306.3% -400.0% -514.0% -290.6% -384.5% 57.1% -31.4% -92.8% -35.2% ·
Pretax Margin 11-point trend, -750.5% -297.3% -121.1% -306.5% -396.5% -513.5% -290.3% -383.9% 57.2% -31.2% -92.3% -35.0% ·
EBITDA Margin 11-point trend, -1892.6% -253.7% -102.7% -284.8% -395.4% -425.0% -269.8% -374.3% 58.4% -15.3% -68.2% -12.7% ·
ROA 11-point trend, -226.6% -56.2% -33.9% -49.8% -40.3% -39.5% -25.3% -21.3% 51.2% -17.9% -28.8% -17.2% ·
ROE 11-point trend, -31.7% -500.1% -217.0% -190.2% -94.5% -70.7% -39.5% -30.4% 38.9% -109.9% -324.7% -379.7% ·
ROIC 11-point trend, +66.1% -155.8% -172.9% -201.2% -103.5% -65.7% -39.5% -31.4% 40.0% -68.3% -128.8% -459.7% ·
Liquidez y Solvencia 3
Datos anuales de Liquidez y Solvencia para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -13.0% 5.0 4.3 6.5 8.0 9.3 9.8 4.0 17.5 5.8 5.9 5.7 ·
Quick Ratio 11-point trend, -94.7% 0.3 0.7 0.7 1.4 0.6 2.1 0.4 2.9 5.4 5.6 5.4 ·
Interest Coverage 6-point trend, -3762.2% · · · · · -62.1 -20.6 31.9 -2.7 -5.0 -1.6 ·
Eficiencia 3
Datos anuales de Eficiencia para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, -61.3% 0.2 0.3 0.2 0.1 0.1 0.1 0.1 0.9 0.6 0.3 0.5 ·
Inventory Turnover 10-point trend, +35.8% · 3.8 1.9 1.2 1.6 1.4 1.8 2.2 2.8 2.7 2.8 ·
Receivables Turnover 10-point trend, +733.7% · 163.4 25.1 6.5 3.3 4.0 2.9 49.5 29.7 9.3 19.6 ·
Por Acción 5
Datos anuales de Por Acción para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +9180.2% $4.41 $0.33 $0.68 $1.94 $3.66 $5.98 $7.96 $9.90 $0.55 $0.58 $0.05 ·
Revenue / Share 8-point trend, -50.6% $3.27 $0.48 $0.47 $0.49 $0.56 $0.86 $0.66 $6.63 · · · ·
Cash Flow / Share 8-point trend, -410.0% $-12.36 $-0.85 $-1.01 $-1.62 $-2.25 $-1.75 $-1.88 $3.99 · · · ·
Cash / Share 11-point trend, +80.6% $0.74 $0.24 $0.18 $0.47 $0.14 $1.10 $0.55 $1.12 $0.03 $0.39 $0.41 ·
EPS (TTM) 12-point trend, -2062.2% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $3.78 $-0.62 $-1.10 $-0.61 $-0.45
Tasas de Crecimiento 3
Datos anuales de Tasas de Crecimiento para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -31.6% -43.9% 9.2% -2.1% -9.7% -33.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +3.1% -15.7% -1.1% -16.2% · · · · · · · · ·
Revenue CAGR 5Y -18.4% · · · · · · · · · · ·
Valoración (TTM) 10
Datos anuales de Valoración (TTM) para NKTR
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -72.5% $55M $98M $90M $92M $102M $153M $115M $1.19B $308M $165M $231M $201M
Net Income TTM 12-point trend, -204.3% $-164M $-119M $-276M $-368M $-524M $-444M $-441M $681M $-97M $-154M $-81M $-54M
Market Cap 11-point trend, -97.5% $862M $2.59B $1.61B $6.39B $37.59B $45.92B $57.16B $85.56B $142.90B $28.20B $34.19B ·
P/E 12-point trend, +99.2% -4.3 -1.6 -5.8 -17.2 -70.9 -102.4 -128.5 130.4 -1444.8 -167.3 -414.3 -516.7
P/S 11-point trend, -89.5% 15.6 26.3 17.8 69.4 368.8 300.3 498.7 71.7 464.4 170.5 148.2 ·
P/B 11-point trend, -99.8% 9.6 42.7 12.3 17.4 55.3 42.6 40.7 49.8 1627.1 320.0 5318.8 ·
P / Tangible Book 6-point trend, -79.1% 9.6 42.7 12.3 22.0 62.3 45.9 · · · · · ·
P / Cash Flow 11-point trend, +99.1% -4.1 -14.7 -8.3 -21.0 -91.1 -146.6 -173.9 119.1 -1777.1 -241.0 -467.9 ·
P / FCF 11-point trend, +99.0% -4.1 -14.6 -8.3 -20.6 -87.9 -143.3 -161.0 121.5 -1586.2 -228.5 -405.7 ·
Earnings Yield 12-point trend, -12010.5% -23.0% -62.2% -17.3% -5.8% -1.4% -0.98% -0.78% 0.77% -0.07% -0.60% -0.24% -0.19%

Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años

Estado de resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ingresos $55M$98M$90M$92M$102M
Margen Operativo % -253.7%-106.9%-292.6%-408.6%-437.8%
Beneficio neto $-164M$-119M$-276M$-368M$-524M
EPS Diluido $-9.73$-8.68$-1.45$-1.97$-2.86
Balance general
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ratio corriente 5.04.36.58.09.3
Ratio Rápido 0.30.70.71.40.6
Flujo de Efectivo
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flujo de caja libre $-209M$-177M$-193M$-310M$-428M

Últimas noticias Noticias recientes que mencionan a esta empresa

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Propietarios institucionales (13F) 269 declarantes · $2.1B total · A fecha de 30 de junio de 2026

Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.

Actividad institucional — Q2 2026 vs trimestre anterior
Nuevas posiciones Posiciones cerradas Aumentado Disminuido Cambio neto de acciones
88 (+20 vs trimestre anterior) 41 (+9 vs trimestre anterior) 91 (+21 vs trimestre anterior) 48 (-8 vs trimestre anterior) +8.5M

Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.

Institución Valor Acciones % de 13F rastreadas Tipo
Two Seas Capital LP $215 868 856 3 092 234 10,35% Acciones
FMR LLC $192 088 149 2 751 585 9,21% Acciones
BVF INC/IL $166 920 946 2 391 075 8,00% Acciones
VANGUARD CAPITAL MANAGEMENT LLC $104 495 029 1 496 849 5,01% Acciones
TWO SIGMA INVESTMENTS, LP $83 911 899 1 202 004 4,02% Acciones
Vestal Point Capital, LP $69 810 000 1 000 000 3,35% Acciones
STATE STREET CORP $63 504 691 909 679 3,04% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $57 502 497 823 700 2,76% Opción de compra
Prosight Management, LP $56 546 100 810 000 2,71% Acciones
GEODE CAPITAL MANAGEMENT, LLC $52 759 799 755 586 2,53% Acciones
ARMISTICE CAPITAL, LLC $50 542 440 724 000 2,42% Acciones
GILDER GAGNON HOWE & CO LLC $41 946 944 600 873 2,01% Acciones
MILLENNIUM MANAGEMENT LLC $33 377 557 478 120 1,60% Acciones
BRAIDWELL LP $33 063 203 473 617 1,59% Acciones
Sofinnova Investments, Inc. $32 933 775 471 763 1,58% Acciones
Woodline Partners LP $32 871 784 470 875 1,58% Acciones
ORBIMED ADVISORS LLC $32 485 804 465 346 1,56% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $27 540 045 394 500 1,32% Opción de venta
EMERALD ADVISERS, LLC $27 236 930 390 158 1,31% Acciones
VANGUARD PORTFOLIO MANAGEMENT LLC $24 331 577 348 540 1,17% Acciones
DAFNA Capital Management LLC $22 226 108 318 380 1,07% Acciones
Deep Track Capital, LP $20 943 000 300 000 1,00% Acciones
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19 893 826 284 971 0,95% Acciones
22NW, LP $19 624 638 281 115 0,94% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $19 475 384 278 977 0,93% Acciones
PRIMECAP MANAGEMENT CO/CA/ $19 047 658 272 850 0,91% Acciones
Nearwater Capital Markets, Ltd $18 255 315 261 500 0,88% Acciones
BARCLAYS PLC $17 968 815 257 396 0,86% Acciones
EMERALD MUTUAL FUND ADVISERS TRUST $17 842 528 255 587 0,86% Acciones
ADAR1 Capital Management, LLC $17 046 485 244 184 0,82% Acciones
Creek Drive Management Group LLC $16 963 830 243 000 0,81% Acciones
SEVEN GRAND MANAGERS, LLC $16 754 400 240 000 0,80% Acciones
VANGUARD FIDUCIARY TRUST CO $16 724 731 239 575 0,80% Acciones
NORGES BANK $15 030 093 215 300 0,72% Acciones
Bronte Capital Management Pty Ltd. $13 852 678 198 434 0,66% Acciones
TWO SIGMA ADVISERS, LP $13 039 744 308 414 0,63% Acciones
CITADEL ADVISORS LLC $12 251 655 175 500 0,59% Opción de venta
GREAT POINT PARTNERS LLC $12 216 750 175 000 0,59% Acciones
Caption Management, LLC $11 944 491 171 100 0,57% Opción de compra
MILLENNIUM MANAGEMENT LLC $11 867 700 170 000 0,57% Opción de compra
CITADEL ADVISORS LLC $11 434 878 163 800 0,55% Opción de compra
AMERIPRISE FINANCIAL INC $11 050 085 158 288 0,53% Acciones
Quinn Opportunity Partners LLC $10 686 236 153 076 0,51% Acciones
GOLDMAN SACHS GROUP INC $10 011 801 143 415 0,48% Acciones
Rhenman & Partners Asset Management AB $9 860 662 141 250 0,47% Acciones
Qube Research & Technologies Ltd $9 111 671 130 521 0,44% Acciones
LMR Partners LLP $9 075 300 130 000 0,44% Opción de venta
Soleus Capital Management, L.P. $8 960 951 128 362 0,43% Acciones
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. $8 570 364 122 767 0,41% Acciones
Stonepine Capital Management, LLC $8 422 856 120 654 0,40% Acciones
SummitTX Capital, L.P. $7 883 923 112 934 0,38% Acciones
APEIRON CAPITAL Ltd $7 429 948 106 431 0,36% Acciones
CITIGROUP INC $7 034 824 100 771 0,34% Acciones
ING GROEP NV $6 981 000 100 000 0,33% Acciones
LMR Partners LLP $6 981 000 100 000 0,33% Acciones
Susquehanna Portfolio Strategies, LLC $6 685 704 95 770 0,32% Acciones
Militia Capital Management LLC $6 282 900 90 000 0,30% Acciones
ACT CAPITAL MANAGEMENT, LLC $6 234 033 89 300 0,30% Acciones
Tetragon Partners GP Ltd $6 073 191 86 996 0,29% Acciones
READYSTATE ASSET MANAGEMENT LP $5 941 529 85 110 0,28% Acciones
Birchview Capital, LP $5 654 610 81 000 0,27% Acciones
BlackRock, Inc. $5 444 412 77 989 0,26% Acciones
GROUP ONE TRADING LLC $4 912 600 70 371 0,24% Acciones
ALGERT GLOBAL LLC $4 686 345 67 130 0,22% Acciones
Moody Aldrich Partners LLC $4 477 264 64 135 0,21% Acciones
WOLVERINE TRADING, LLC $4 330 620 73 500 0,21% Opción de venta
Swiss National Bank $4 300 296 61 600 0,21% Acciones
F/m Investments LLC $4 229 439 60 585 0,20% Acciones
BANK OF AMERICA CORP /DE/ $4 227 764 60 561 0,20% Acciones
ExodusPoint Capital Management, LP $4 084 374 58 507 0,20% Acciones
Trexquant Investment LP $3 956 831 56 680 0,19% Acciones
K2 PRINCIPAL FUND, L.P. $3 522 962 50 465 0,17% Acciones
WOLVERINE TRADING, LLC $3 403 101 57 758 0,16% Acciones
RHUMBLINE ADVISERS $3 008 381 43 094 0,14% Acciones
MORGAN STANLEY $2 943 050 42 158 0,14% Acciones
Voleon Capital Management LP $2 850 901 40 838 0,14% Acciones
Anson Funds Management LP $2 829 748 40 535 0,14% Acciones
Atom Investors LP $2 828 631 40 519 0,14% Acciones
WOLVERINE TRADING, LLC $2 792 808 47 400 0,13% Opción de compra
Burkehill Global Management, LP $2 792 400 40 000 0,13% Acciones
NOMURA HOLDINGS INC $2 792 400 40 000 0,13% Opción de venta
IRIDIAN ASSET MANAGEMENT LLC/CT $2 708 768 38 802 0,13% Acciones
NOMURA HOLDINGS INC $2 698 645 38 657 0,13% Acciones
Jefferies Financial Group Inc. $2 664 299 38 165 0,13% Acciones
ALLIANCEBERNSTEIN L.P. $2 590 200 36 000 0,12% Acciones
Connor, Clark & Lunn Investment Management Ltd. $2 575 780 36 897 0,12% Acciones
ALPS ADVISORS INC $2 386 664 34 188 0,11% Acciones
FRED ALGER MANAGEMENT, LLC $2 350 712 33 673 0,11% Acciones
TUDOR INVESTMENT CORP ET AL $2 345 616 33 600 0,11% Opción de compra
Bank of New York Mellon Corp $2 306 522 33 040 0,11% Acciones
Ghisallo Capital Management LLC $2 233 920 32 000 0,11% Acciones
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $2 063 670 28 682 0,10% Acciones
Blackstone Inc. $2 002 011 28 678 0,10% Acciones
KVP Capital Advisors, LP $1 877 889 26 900 0,09% Acciones
Ishara Investments LP $1 860 437 26 650 0,09% Acciones
Erste Asset Management GmbH $1 830 920 28 000 0,09% Acciones
Caption Management, LLC $1 822 041 26 100 0,09% Opción de venta
WINTON GROUP Ltd $1 808 079 25 900 0,09% Acciones
K2 PRINCIPAL FUND, L.P. $1 745 250 25 000 0,08% Opción de compra
Empowered Funds, LLC $1 636 416 23 441 0,08% Acciones

Informantes de la empresa 40 insiders · 20 directivos · 18 consejeros

Insider Rol Última actividad Acciones en propiedad Compras 12m Ventas 12m Neto 12m
Howard W Robin President & CEO 24 de julio de 2026 A 55 045 0 20 $-2 224 055
Jillian B. Thomsen Chief Financial Officer 16 de febrero de 2023 S 313 497 0 0 $0
Gil M Labrucherie SVP, COO & CFO 16 de mayo de 2022 S 312 905 0 0 $0
Timothy Harkness SVP & Chief Financial Officer 23 de agosto de 2007 A 0 0 $0
Louis Drapeau Sr. VP Finance, CFO 14 de mayo de 2007 A 6 000 0 0 $0
Milton J Harris President of Nektar AL 4 de marzo de 2004 S 743 904 0 0 $0
John Nicholson SVP & Chief Operating Officer 16 de agosto de 2019 S 162 759 0 0 $0
Bharat M Chowrira Chief Operating Officer 1 de febrero de 2010 A 0 0 $0
Jonathan Zalevsky Chief R&D Officer 24 de julio de 2026 A 9 756 0 12 $-1 052 364
Mark Andrew Wilson Chief Legal Officer 21 de noviembre de 2025 A 21 585 0 2 $-52 171
John Northcott SVP & Chief Commercial Officer 16 de mayo de 2022 S 223 210 0 0 $0
Stephen K Doberstein SVP & Chief Scientific Officer 5 de septiembre de 2019 P 107 668 0 0 $0
Maninder Hora SVP Pharma Dev & Mfg Ops 16 de mayo de 2019 S 94 694 0 0 $0
Ivan P. Gergel SVP & Chief Medical Officer 15 de noviembre de 2017 A 56 553 0 0 $0
Robert Medve SVP & Chief Medical Officer 5 de febrero de 2014 A 0 0 $0
Rinko Ghosh Chief Business Officer 6 de febrero de 2013 A 9 753 0 0 $0
Randall W Moreadith SVP Drug Development 23 de febrero de 2009 A 0 0 $0
John Stuart Patton Chief Scientific Officer 14 de noviembre de 2008 M 313 880 0 0 $0
Nevan C Elam SVP & Head of Pulmonary Bus 25 de febrero de 2008 A 1 400 0 0 $0
David Johnston SVP, Research & Development 14 de mayo de 2007 D 6 600 0 0 $0
Diana Brainard Consejero 30 de septiembre de 2025 A 28 560 0 0 $0
Jeffrey Robert Ajer Consejero 30 de septiembre de 2025 A 34 153 0 0 $0
Robert Chess Consejero 30 de septiembre de 2025 A 255 273 0 0 $0
Scott R Greer Consejero 30 de septiembre de 2025 A 303 574 0 0 $0
Roy A Whitfield Consejero 30 de septiembre de 2025 A 216 250 0 0 $0
Myriam Curet Consejero 19 de septiembre de 2023 A 27 418 0 0 $0
Karin Eastham Consejero 16 de septiembre de 2022 A 23 233 0 0 $0
Lutz Lingnau Consejero 22 de septiembre de 2020 A 35 800 0 0 $0
Christopher A Kuebler Consejero 27 de septiembre de 2018 A 45 250 0 0 $0
Dennis L Winger Consejero 21 de agosto de 2018 M 42 750 0 0 $0
Joseph J Krivulka Consejero 19 de septiembre de 2017 A 82 000 0 0 $0
Susan Wang Consejero 20 de noviembre de 2015 M 20 000 0 0 $0
BROWN MICHAEL A/CA Consejero 15 de septiembre de 2009 A 10 000 0 0 $0
Hoyoung Huh Consejero 2 de diciembre de 2008 A 0 0 $0
Irwin Lerner Consejero 2 de diciembre de 2008 A 10 000 0 0 $0
James B Glavin Consejero 4 de septiembre de 2003 A 0 0 $0
Masuoka K. Lorianne 8 de febrero de 2011 A 0 0 $0
Ajit Gill President & CEO 23 de marzo de 2006 S 87 991 0 0 $0
Ajay Bansal 10 de marzo de 2006 S 5 166 0 0 $0
Melvin Perelman 2 de septiembre de 2004 A 0 0 $0

Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto

Activistas y propietarios del %+ 5 1 tenencia

Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.

Declarante Presentado Participación Estado Propósito Presentación
Nektar Therapeutics ( 22 de agosto de 2005 Presentación inicial M&A / venta SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Propiedad de ETFs Mantenido por 28 ETFs

El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.

Fondo Ponderación Unidades A fecha de Fuente
LFSC · RBB Fund, Inc. 3,14% 50 876 NS 31 de mayo de 2026 N-PORT
SPIT · RBB Fund, Inc. 3,11% 10 455 NS 30 de abril de 2026 N-PORT
PILL · Direxion Shares ETF Trust 1,55% 2 353 NS 30 de abril de 2026 N-PORT
BBC · ETFis Series Trust I 1,15% 5 045 NS 30 de abril de 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0,58% 1 726 SH 8 de agosto de 2026 Diario
IHE · iShares Trust 0,55% 120 730 SH 8 de agosto de 2026 Diario
PRFZ · Invesco Exchange-Traded Fund Trust 0,16% 59 612 SH 8 de agosto de 2026 Diario
IWO · iShares Trust 0,14% 278 376 SH 8 de agosto de 2026 Diario
VTWG · VANGUARD SCOTTSDALE FUNDS 0,13% 33 135 SH 8 de agosto de 2026 Diario
TMFX · RBB Fund, Inc. 0,09% 455 NS 31 de mayo de 2026 N-PORT
IWM · iShares Trust 0,08% 877 973 SH 8 de agosto de 2026 Diario
VTWO · VANGUARD SCOTTSDALE FUNDS 0,07% 198 365 SH 8 de agosto de 2026 Diario
ISCV · iShares Trust 0,07% 6 414 SH 8 de agosto de 2026 Diario
SCHA · SCHWAB STRATEGIC TRUST 0,04% 151 830 NS 31 de mayo de 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0,03% 11 131 NS 30 de abril de 2026 N-PORT
ISCB · iShares Trust 0,03% 1 294 SH 8 de agosto de 2026 Diario
VXF · VANGUARD INDEX FUNDS 0,03% 387 471 SH 8 de agosto de 2026 Diario
VHT · VANGUARD WORLD FUND 0,03% 92 340 SH 8 de agosto de 2026 Diario
WSML · iShares Trust 0,02% 1 887 SH 8 de agosto de 2026 Diario
VTWV · VANGUARD SCOTTSDALE FUNDS 0,02% 3 096 SH 8 de agosto de 2026 Diario
IWN · iShares Trust 0,02% 32 466 SH 8 de agosto de 2026 Diario
ONEQ · Fidelity Commonwealth Trust 0,00% 6 903 NS 31 de mayo de 2026 N-PORT
ITOT · iShares Trust 0,00% 48 124 SH 8 de agosto de 2026 Diario
IWV · iShares Trust 0,00% 9 139 SH 8 de agosto de 2026 Diario
TILT · FlexShares Trust 0,00% 770 NS 30 de abril de 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0,00% 18 540 NS 31 de mayo de 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0,00% 1 075 430 SH 8 de agosto de 2026 Diario
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 2 837 SH 8 de agosto de 2026 Diario