ORIC Oric Pharmaceuticals, Inc. - Common Stock
$14,35
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 3, 2026
Rango 52S
$7–$15
92% of range
Calificación del Analista
BUY
21 analysts
Precio Objetivo
$21
+44% upside
P/E (TTM)
-10.3
ROE
-36.5%
Margen de Beneficio Neto
—
ORIC Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$14.35
Capitalización Bursátil
$1.49B
P/E (TTM)
-10.3
BPA (TTM)
$-1.47
Ingresos (TTM)
—
Rendimiento div.
—
ROE
-36.5%
Deuda/Capital
—
Rango 52S
$7 – $15
ORIC Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-1.47
2021-12-31
→
2025-12-31
Flujo de caja libre
$-112M
2020-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
ORIC
Mediana de Pares
P/E (TTM)
-10.3
—
P/B (P/C)
3.9
3.6
Price / FCF (Precio / FCF)
-13.3
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
ORIC
Mediana de Pares
ROA
-37.9%
-40.9%
ROE
-36.5%
-47.9%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
ORIC
Mediana de Pares
Current Ratio (Ratio corriente)
14.1
8.3
Quick Ratio (Ratio Rápido)
2.2
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
ORIC
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
ORIC
Mediana de Pares
ORIC Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
21 analistas
- Compra fuerte 9 42,9%
- Compra 10 47,6%
- Mantener 2 9,5%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
12 analistas · 2026-08-19
Mediana
$21.50
Ahora
$14.35
Mín
$14.00
Máx
$27.00
Objetivo mediano
$21.50
+49,8%
Objetivo medio
$20.67
+44,0%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.04%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.38 | $-0.37 | -0.01% |
| 31 de marzo de 2026 | $-0.34 | $-0.33 | -0.01% |
| 31 de diciembre de 2025 | $-0.30 | $-0.37 | 0.07% |
| 30 de septiembre de 2025 | $-0.33 | $-0.41 | 0.08% |
| 30 de junio de 2025 | $-0.47 | $-0.45 | -0.02% |
| 31 de marzo de 2025 | $-0.42 | $-0.52 | 0.10% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| ORIC | $806M | -5.6 | — | — | -36.5% | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
| PURR | — | — | — | — | — | — |
| AKTS | — | — | — | — | — | — |
| CGEM | $624M | -3.2 | — | — | -44.0% | — |
| NVAX | $1.09B | 2.6 | 64.7% | 39.2% | -977.1% | — |
| INBX | $1.15B | -8.7 | 550.0% | -10773.5% | -365.9% | — |
| GLUE | $1.03B | — | 63.5% | -31.2% | -15.4% | — |
| MGTX | $645M | -5.6 | 144.6% | -140.3% | 8062.2% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 11
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $33M | $29M | $26M | $25M | $22M | $13M | $6M | |
| Operating Expenses | $143M | $143M | $111M | $92M | $79M | $74M | $29M | |
| Operating Income | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | $-29M | |
| Other Non-op | $14M | $15M | $10M | $3M | $156.0K | $483.0K | $2M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | $-27M | |
| EPS (Basic) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| EPS (Diluted) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| Shares (Basic) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| Shares (Diluted) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| EBITDA | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | · |
Balance general 22
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $46M | $59M | $23M | $67M | $226M | $78M | $89M | |
| Short-term Investments | · | · | · | · | · | $215M | · | |
| Prepaid Expense | $7M | $6M | $4M | $4M | $4M | $3M | $840.0K | |
| Current Assets | $288M | $262M | $213M | $210M | $241M | $297M | $90M | |
| PP&E (Net) | $2M | $3M | $3M | $3M | $2M | $2M | $2M | |
| PP&E (Gross) | $10M | $10M | $9M | $9M | $7M | $6M | $6M | |
| Accum. Depreciation | $8M | $7M | $6M | $6M | $5M | $4M | $4M | |
| Other Non-current Assets | $7M | $9M | $10M | $12M | $12M | $319.0K | $2M | |
| Total Assets | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Accounts Payable | $4M | $2M | $944.0K | $1M | $2M | $757.0K | $152.0K | |
| Accrued Liabilities | $17M | $23M | $20M | $14M | $13M | $8M | $5M | |
| Current Liabilities | $20M | $25M | $20M | $15M | $15M | $9M | $5M | |
| Capital Leases | $4M | $6M | $7M | $9M | $10M | · | · | |
| Other Non-current Liabilities | $4M | $6M | $7M | $9M | $11M | $219.0K | · | |
| Total Liabilities | $25M | $31M | $28M | $25M | $26M | $9M | $6M | |
| Long-term Debt | · | · | · | · | $10M | · | · | |
| Common Stock | $11.0K | $7.0K | $6.0K | $5.0K | $4.0K | $4.0K | · | |
| Retained Earnings | $-692M | $-563M | $-435M | $-334M | $-245M | $-166M | $-93M | |
| AOCI | $786.0K | $379.0K | $258.0K | $-1M | $-103.0K | $-31.0K | · | |
| Stockholders' Equity | $384M | $243M | $224M | $222M | $273M | $290M | $-90M | |
| Liabilities + Equity | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Shares Outstanding | 98,528,949 | 71,021,855 | 54,865,553 | 45,089,537 | 39,430,120 | 36,672,415 | 1,984,222 |
Flujo de Efectivo 9
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $25M | $20M | $15M | $14M | $13M | $5M | $1M | |
| Operating Cash Flow | $-111M | $-113M | $-86M | $-75M | $-60M | $-45M | $-24M | |
| CapEx | $712.0K | $1M | $849.0K | $2M | $939.0K | $667.0K | $768.0K | |
| Investing Cash Flow | $-148M | $22M | $-43M | $-109M | $158M | $-216M | $-768.0K | |
| Stock Issued | $244M | $125M | $85M | $25M | $50M | $271M | · | |
| Net Stock Activity | $244M | $125M | $85M | $25M | $50M | $133M | · | |
| Financing Cash Flow | $245M | $127M | $86M | $25M | $49M | $251M | $71M | |
| Net Change in Cash | $-14M | $36M | $-43M | $-159M | $148M | $-11M | $47M | |
| Free Cash Flow | $-112M | $-114M | $-87M | $-77M | $-60M | $-46M | · |
Rentabilidad 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -37.9% | -48.6% | -40.3% | -32.7% | -26.3% | -37.5% | · | |
| ROE | -36.5% | -49.5% | -42.7% | -40.8% | -27.9% | -31.1% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 | 33.0 | · | |
| Quick Ratio | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 | 32.6 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | · | |
| Market Cap | $806M | $573M | $505M | $266M | $580M | $1.24B | · | |
| P/E | -5.6 | -4.4 | -4.7 | -2.6 | -7.1 | · | · | |
| P/B | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Tangible Book | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Cash Flow | -7.3 | -5.1 | -5.9 | -3.5 | -9.7 | -27.4 | · | |
| P / FCF | -7.2 | -5.0 | -5.8 | -3.4 | -9.6 | -27.0 | · | |
| Earnings Yield | -18.0% | -22.7% | -21.3% | -38.2% | -14.1% | · | · |
Estado de resultados 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $9M | $8M | $9M | $8M | $9M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $6M | $6M | $6M | $6M | |
| Operating Expenses | $45M | $40M | $35M | $37M | $39M | $33M | $40M | $38M | $36M | $29M | $31M | $29M | $25M | $26M | $22M | $26M | |
| Operating Income | $-45M | $-40M | $-35M | $-37M | $-39M | $-33M | $-40M | $-38M | $-36M | $-29M | $-31M | $-29M | $-25M | $-26M | $-22M | $-26M | |
| Other Non-op | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $4M | $4M | $4M | $3M | $3M | $2M | $2M | $1M | $865.0K | |
| Net Income | $-41M | $-36M | $-31M | $-33M | $-36M | $-30M | $-36M | $-35M | $-32M | $-25M | $-28M | $-25M | $-23M | $-24M | $-21M | $-25M | |
| EPS (Basic) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| EPS (Diluted) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| Shares (Basic) | 108,012,388 | 105,472,766 | -160,326,367 | 98,953,331 | 78,126,257 | 71,040,580 | -138,512,709 | 70,542,684 | 70,348,414 | 67,349,551 | -96,695,752 | 57,402,226 | 45,654,208 | 45,090,166 | -78,833,750 | 39,575,660 | |
| Shares (Diluted) | 108,012,388 | 105,472,766 | -160,326,367 | 98,953,331 | 78,126,257 | 71,040,580 | -138,512,709 | 70,542,684 | 70,348,414 | 67,349,551 | -96,695,752 | 57,402,226 | 45,654,208 | 45,090,166 | -78,833,750 | 39,575,660 | |
| EBITDA | $-45M | $-40M | · | $-37M | $-39M | $-33M | · | $-38M | $-36M | $-29M | · | $-29M | $-25M | $-26M | · | $-26M |
Balance general 20
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $37M | $56M | $46M | $50M | $76M | $49M | $59M | $44M | $50M | $56M | $23M | $26M | $104M | $59M | $67M | $29M | |
| Prepaid Expense | $9M | $8M | $7M | $8M | $9M | $8M | $6M | $7M | $8M | $7M | $4M | $5M | $4M | $4M | $4M | $5M | |
| Current Assets | $274M | $290M | $288M | $296M | $291M | $211M | $262M | $279M | $295M | $324M | $213M | $232M | $268M | $193M | $210M | $199M | |
| PP&E (Net) | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | |
| PP&E (Gross) | $10M | $10M | $10M | $11M | $11M | $11M | $10M | $10M | $10M | $9M | $9M | $10M | $10M | $9M | $9M | $9M | |
| Accum. Depreciation | $8M | $8M | $8M | $8M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $7M | $6M | $6M | $6M | $6M | |
| Other Non-current Assets | $6M | $7M | $7M | $7M | $8M | $8M | $9M | $10M | $9M | $9M | $10M | $10M | $11M | $11M | $12M | $12M | |
| Total Assets | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Accounts Payable | $4M | $3M | $4M | $3M | $3M | $5M | $2M | $4M | $2M | $3M | $944.0K | $4M | $3M | $2M | $1M | $2M | |
| Accrued Liabilities | $17M | $15M | $17M | $17M | $15M | $12M | $23M | $17M | $17M | $12M | $20M | $15M | $11M | $13M | $14M | $12M | |
| Current Liabilities | $21M | $18M | $20M | $20M | $18M | $18M | $25M | $21M | $20M | $15M | $20M | $19M | $15M | $15M | $15M | $13M | |
| Capital Leases | · | · | $4M | · | · | · | $6M | · | · | · | $7M | · | · | · | $9M | · | |
| Other Non-current Liabilities | $3M | $3M | $4M | $4M | $5M | $6M | $6M | $7M | $7M | $7M | $7M | $8M | $8M | $9M | $9M | $10M | |
| Total Liabilities | $23M | $21M | $25M | $24M | $23M | $23M | $31M | $28M | $27M | $22M | $28M | $27M | $23M | $24M | $25M | $23M | |
| Common Stock | $11.0K | $11.0K | $11.0K | $11.0K | $9.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $6.0K | $6.0K | $6.0K | $5.0K | $5.0K | $4.0K | |
| Retained Earnings | $-770M | $-728M | $-692M | $-662M | $-629M | $-593M | $-563M | $-526M | $-492M | $-460M | $-435M | $-407M | $-381M | $-358M | $-334M | $-313M | |
| AOCI | $-1M | $-290.0K | $786.0K | $615.0K | $187.0K | $209.0K | $379.0K | $722.0K | $-256.0K | $-162.0K | $258.0K | $-369.0K | $-567.0K | $-499.0K | $-1M | $-2M | |
| Stockholders' Equity | $381M | $416M | $384M | $407M | $324M | $220M | $243M | $274M | $302M | $329M | $224M | $247M | $269M | $203M | $222M | $215M | |
| Liabilities + Equity | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Shares Outstanding | 103,636,424 | 103,486,412 | 98,528,949 | 97,278,032 | 86,187,328 | 71,078,511 | 71,021,855 | 70,559,183 | 67,672,303 | 67,420,338 | 54,865,553 | 54,540,715 | 54,532,171 | 45,091,215 | 45,089,537 | 39,576,047 |
Flujo de Efectivo 9
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $7M | $7M | $6M | $6M | $7M | $7M | $5M | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $3M | $3M | |
| Operating Cash Flow | $-32M | $-32M | $-22M | $-25M | $-31M | $-33M | $-28M | $-29M | $-26M | $-30M | $-24M | $-20M | $-21M | $-21M | $-15M | $-19M | |
| CapEx | $356.0K | $2.0K | $227.0K | $35.0K | $63.0K | $387.0K | $219.0K | $418.0K | $333.0K | $218.0K | $57.0K | $77.0K | $405.0K | $310.0K | $287.0K | $401.0K | |
| Investing Cash Flow | $12M | $-18M | $17M | $-111M | $-77M | $22M | $43M | $23M | $18M | $-62M | $21M | $-58M | $-19M | $13M | $28M | $-685.0K | |
| Stock Issued | $0 | $61M | $0 | $110M | $134M | $0 | $0 | $0 | $0 | $125M | $0 | $226.0K | $85M | $0 | $25M | $-354.0K | |
| Net Stock Activity | · | $61M | · | · | · | $0 | · | · | · | $125M | · | · | · | · | · | · | |
| Financing Cash Flow | $828.0K | $61M | $2M | $109M | $134M | $11.0K | $575.0K | $126.0K | $816.0K | $125M | $453.0K | $31.0K | $85M | $0 | $25M | $1.0K | |
| Net Change in Cash | $-19M | $11M | $-4M | $-26M | $27M | $-10M | $15M | $-6M | $-7M | $33M | $-3M | $-77M | $45M | $-8M | $38M | $-20M | |
| Free Cash Flow | · | $-32M | · | · | · | $-33M | · | · | · | $-30M | · | · | · | $-21M | · | · |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -11.0% | -10.5% | · | -8.9% | -10.8% | -10.1% | · | -12.0% | -10.3% | -8.7% | · | -10.0% | -8.3% | -9.6% | · | -9.0% | |
| ROE | -11.8% | -11.3% | · | -9.6% | -11.6% | -10.9% | · | -13.3% | -11.2% | -9.4% | · | -11.0% | -9.1% | -10.5% | · | -9.8% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.2 | 16.3 | · | 14.6 | 16.1 | 12.0 | · | 13.2 | 15.1 | 21.3 | · | 12.3 | 18.5 | 13.0 | · | 15.0 | |
| Quick Ratio | 1.8 | 3.2 | · | 2.5 | 4.2 | 2.8 | · | 2.1 | 2.6 | 3.7 | · | 1.4 | 7.1 | 4.0 | · | 2.2 |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-146M | $-135M | · | $-134M | $-133M | $-122M | · | $-117M | $-105M | $-97M | · | $-97M | $-92M | $-92M | · | $-87M | |
| Market Cap | $1.12B | $1.31B | · | $1.17B | $875M | $397M | · | $723M | $478M | $927M | · | $330M | $423M | $257M | · | $127M | |
| P/E | -7.1 | -8.1 | · | -7.0 | -5.5 | -3.2 | · | -5.9 | -4.0 | -7.5 | · | -2.9 | -3.6 | -2.5 | · | -1.5 | |
| P/B | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Tangible Book | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Cash Flow | · | -40.4 | · | · | · | -12.2 | · | · | · | -30.7 | · | · | · | -12.5 | · | · | |
| P / FCF | · | -40.4 | · | · | · | -12.0 | · | · | · | -30.5 | · | · | · | -12.3 | · | · | |
| Earnings Yield | -14.0% | -12.3% | · | -14.2% | -18.0% | -31.0% | · | -17.1% | -24.9% | -13.4% | · | -34.7% | -28.0% | -39.6% | · | -68.8% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-129M | $-128M | $-101M | $-89M | $-79M |
| EPS Diluido | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 |
| Ratio Rápido | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-112M | $-114M | $-87M | $-77M | $-60M |
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Propietarios institucionales (13F) 192 declarantes · $1.1B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 40 (+4 vs trimestre anterior) | 28 (+10 vs trimestre anterior) | 68 (+17 vs trimestre anterior) | 44 (-18 vs trimestre anterior) | +10.7M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Nextech Invest Ltd. | $77 571 359 | 7 162 637 | 6,91% | Acciones |
| EcoR1 Capital, LLC | $72 865 496 | 6 728 116 | 6,49% | Acciones |
| VIKING GLOBAL INVESTORS LP | $55 522 832 | 5 126 762 | 4,95% | Acciones |
| STATE STREET CORP | $53 002 020 | 4 894 000 | 4,72% | Acciones |
| SR One Capital Management, LP | $49 984 609 | 4 615 384 | 4,45% | Acciones |
| Venrock Adviser, LLC | $46 783 055 | 4 319 765 | 4,17% | Acciones |
| NEA Management Company, LLC | $44 604 665 | 4 118 621 | 3,97% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $42 791 160 | 3 951 169 | 3,81% | Acciones |
| Nextech Invest Ltd. | $42 655 712 | 5 285 714 | 3,80% | Acciones |
| AIHC Capital Management Ltd | $41 462 222 | 3 828 460 | 3,69% | Acciones |
| Column Group LLC | $38 346 615 | 3 540 777 | 3,42% | Acciones |
| ALKEON CAPITAL MANAGEMENT LLC | $33 845 158 | 3 125 130 | 3,01% | Acciones |
| VANGUARD GROUP INC | $32 441 356 | 3 965 936 | 2,89% | Acciones |
| CITADEL ADVISORS LLC | $23 789 416 | 2 196 622 | 2,12% | Acciones |
| First Turn Management, LLC | $21 847 186 | 2 017 284 | 1,95% | Acciones |
| ORBIMED ADVISORS LLC | $21 822 450 | 2 015 000 | 1,94% | Acciones |
| Integral Health Asset Management, LLC | $20 577 000 | 1 900 000 | 1,83% | Acciones |
| MPM BIOIMPACT LLC | $20 383 814 | 1 882 162 | 1,82% | Acciones |
| Vivo Capital, LLC | $20 022 352 | 1 848 786 | 1,78% | Acciones |
| GOLDMAN SACHS GROUP INC | $19 593 582 | 1 809 195 | 1,75% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $19 414 443 | 1 792 258 | 1,73% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $18 476 857 | 1 706 081 | 1,65% | Acciones |
| FMR LLC | $14 205 494 | 1 311 680 | 1,27% | Acciones |
| Woodline Partners LP | $13 510 587 | 1 247 515 | 1,20% | Acciones |
| ALGERT GLOBAL LLC | $13 161 623 | 1 215 293 | 1,17% | Acciones |
| BRAIDWELL LP | $13 153 468 | 1 214 540 | 1,17% | Acciones |
| Candriam S.C.A. | $12 764 594 | 1 179 768 | 1,14% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11 392 109 | 1 051 903 | 1,01% | Acciones |
| Defilade Capital Management, L.P. | $11 346 483 | 1 047 690 | 1,01% | Acciones |
| Siren, L.L.C. | $10 912 037 | 1 007 575 | 0,97% | Acciones |
| Euclidean Capital LLC | $10 715 310 | 989 410 | 0,95% | Acciones |
| ROYCE & ASSOCIATES LP | $10 609 761 | 979 664 | 0,94% | Acciones |
| EVENTIDE ASSET MANAGEMENT, LLC | $10 337 886 | 954 768 | 0,92% | Acciones |
| Qube Research & Technologies Ltd | $8 604 890 | 794 542 | 0,77% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $8 154 806 | 752 983 | 0,73% | Acciones |
| Jones Hill Capital LP | $8 093 400 | 747 313 | 0,72% | Acciones |
| SILVERARC CAPITAL MANAGEMENT, LLC | $8 001 995 | 738 873 | 0,71% | Acciones |
| NEXTBio Capital Management LP | $7 647 323 | 706 124 | 0,68% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $7 556 026 | 697 694 | 0,67% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7 340 823 | 677 823 | 0,65% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6 808 626 | 628 682 | 0,61% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $6 537 681 | 603 664 | 0,58% | Acciones |
| ArrowMark Colorado Holdings LLC | $6 312 536 | 582 875 | 0,56% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $6 130 192 | 566 038 | 0,55% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $5 614 922 | 518 460 | 0,50% | Acciones |
| SUPERSTRING CAPITAL MANAGEMENT LP | $4 397 814 | 406 077 | 0,39% | Acciones |
| Blue Owl Capital Holdings LP | $4 332 000 | 400 000 | 0,39% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $4 256 948 | 393 070 | 0,38% | Acciones |
| Redmile Group, LLC | $3 920 568 | 362 010 | 0,35% | Acciones |
| Boxer Capital Management, LLC | $3 790 500 | 350 000 | 0,34% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $3 736 762 | 345 038 | 0,33% | Acciones |
| Squarepoint Ops LLC | $3 729 235 | 344 343 | 0,33% | Acciones |
| Pfizer Inc | $3 553 775 | 372 904 | 0,32% | Acciones |
| TD Asset Management Inc | $2 664 202 | 246 002 | 0,24% | Acciones |
| CITIGROUP INC | $2 647 339 | 244 445 | 0,24% | Acciones |
| BANK OF AMERICA CORP /DE/ | $2 638 892 | 243 665 | 0,24% | Acciones |
| Trexquant Investment LP | $2 402 300 | 221 819 | 0,21% | Acciones |
| XTX Topco Ltd | $2 359 066 | 217 827 | 0,21% | Acciones |
| UBS Group AG | $2 266 578 | 209 287 | 0,20% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 935 321 | 178 700 | 0,17% | Opción de compra |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 886 824 | 174 222 | 0,17% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $1 826 241 | 168 628 | 0,16% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 508 251 | 139 266 | 0,13% | Acciones |
| Jump Financial, LLC | $1 423 062 | 131 400 | 0,13% | Acciones |
| Atom Investors LP | $1 408 756 | 130 079 | 0,13% | Acciones |
| Ishara Investments LP | $1 332 090 | 123 000 | 0,12% | Acciones |
| Caption Management, LLC | $1 191 300 | 110 000 | 0,11% | Opción de compra |
| SPHERA FUNDS MANAGEMENT LTD. | $1 083 000 | 100 000 | 0,10% | Opción de compra |
| Caption Management, LLC | $1 083 000 | 100 000 | 0,10% | Opción de venta |
| RHUMBLINE ADVISERS | $1 017 131 | 93 919 | 0,09% | Acciones |
| Rafferty Asset Management, LLC | $982 963 | 90 763 | 0,09% | Acciones |
| Abu Dhabi Investment Council Co P.J.S.C | $968 646 | 89 441 | 0,09% | Acciones |
| Bank of New York Mellon Corp | $965 776 | 89 176 | 0,09% | Acciones |
| Swiss National Bank | $933 546 | 86 200 | 0,08% | Acciones |
| WINTON GROUP Ltd | $898 890 | 83 000 | 0,08% | Acciones |
| BlackRock, Inc. | $864 407 | 79 816 | 0,08% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $808 473 | 63 810 | 0,07% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $745 169 | 68 806 | 0,07% | Acciones |
| WELLS FARGO & COMPANY/MN | $696 228 | 64 287 | 0,06% | Acciones |
| Engineers Gate Manager LP | $693 683 | 64 052 | 0,06% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $612 835 | 48 369 | 0,05% | Acciones |
| Caption Management, LLC | $521 248 | 48 130 | 0,05% | Acciones |
| PROFUND ADVISORS LLC | $494 931 | 45 700 | 0,04% | Acciones |
| MetLife Investment Management, LLC | $474 787 | 43 840 | 0,04% | Acciones |
| TUDOR INVESTMENT CORP ET AL | $459 289 | 42 409 | 0,04% | Acciones |
| Virtus Investment Advisers, LLC | $428 489 | 39 565 | 0,04% | Acciones |
| Optimize Financial Inc | $409 596 | 32 328 | 0,04% | Acciones |
| AXQ CAPITAL, LP | $395 501 | 36 519 | 0,04% | Acciones |
| Quadrature Capital Ltd | $393 086 | 36 296 | 0,04% | Acciones |
| LMR Partners LLP | $381 942 | 35 267 | 0,03% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $372 639 | 34 408 | 0,03% | Acciones |
| AlphaQuest LLC | $363 086 | 44 387 | 0,03% | Acciones |
| Russell Investments Group, Ltd. | $332 914 | 30 740 | 0,03% | Acciones |
| Brevan Howard Capital Management LP | $331 983 | 30 654 | 0,03% | Acciones |
| Invesco Ltd. | $318 456 | 29 405 | 0,03% | Acciones |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $310 626 | 28 682 | 0,03% | Acciones |
| Vanguard Global Advisers, LLC | $306 457 | 28 297 | 0,03% | Acciones |
| D. E. Shaw & Co., Inc. | $287 103 | 26 510 | 0,03% | Acciones |
| CITADEL ADVISORS LLC | $281 580 | 26 000 | 0,03% | Opción de compra |
| VANGUARD ASSET MANAGEMENT, Ltd | $272 797 | 25 189 | 0,02% | Acciones |
Informantes de la empresa 11 insiders · 3 directivos · 9 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Jacob Chacko | President and CEO | 2 de enero de 2024 A | 808 544 | 0 | 0 | $0 |
| Dominic Piscitelli | Chief Financial Officer | 2 de enero de 2024 A | 83 809 | 0 | 0 | $0 |
| Pratik S Multani | Chief Medical Officer | 2 de enero de 2024 A | 23 809 | 0 | 0 | $0 |
| Richard A. Heyman | Consejero | 24 de julio de 2026 M | 206 672 | 0 | 3 | $-161 062 |
| Angie You | Consejero | 14 de junio de 2023 A | — | 0 | 0 | $0 |
| Mardi Dier | Consejero | 14 de junio de 2023 A | — | 0 | 0 | $0 |
| Lori Anne Kunkel | Consejero | 14 de junio de 2023 A | — | 0 | 0 | $0 |
| Steven L. Hoerter | Consejero | 14 de junio de 2023 A | — | 0 | 0 | $0 |
| Peter Svennilson | Consejero | 16 de junio de 2021 A | 4 768 181 | 0 | 0 | $0 |
| GORDON CARL L | Consejero | 16 de junio de 2021 A | 2 212 571 | 0 | 0 | $0 |
| Richard H Scheller | Consejero | 24 de mayo de 2021 S | 39 092 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 2 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| SR One Capital Management, LLC, SR One Capital Opportunities Fund I, LP, SR One Capital Opportunities Partners I, LP, AMZL, LP, SR One Capital SMA Partners, LP, SR One Capital Fund II Aggregator, LP, SR One Capital Partners II, LP, Simeon George ×2 presentaciones | 14 de agosto de 2025 | 4,75% | Enmienda | — | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP VI LLC, OrbiMed Capital LLC ×5 presentaciones | 27 de diciembre de 2022 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 43 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0,78% | 29 424 NS | 30 de abril de 2026 | N-PORT |
| CANC · Tema ETF Trust | 0,28% | 57 977 NS | 31 de mayo de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,24% | 124 292 NS | 30 de abril de 2026 | N-PORT |
| IWC · iShares Trust | 0,22% | 253 807 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,10% | 5 635 SH | 8 de agosto de 2026 | Diario |
| ESSC · Strategy Shares | 0,08% | 2 136 NS | 30 de abril de 2026 | N-PORT |
| IBB · iShares Trust | 0,06% | 453 772 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,04% | 146 225 NS | 31 de mayo de 2026 | N-PORT |
| BIB · ProShares Trust | 0,04% | 3 711 NS | 31 de mayo de 2026 | N-PORT |
| IWN · iShares Trust | 0,04% | 478 494 SH | 8 de agosto de 2026 | Diario |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,04% | 44 861 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,03% | 1 907 813 SH | 8 de agosto de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 62 749 SH | 8 de agosto de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,02% | 327 184 NS | 30 de abril de 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 429 878 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,02% | 28 629 NS | 30 de abril de 2026 | N-PORT |
| IWO · iShares Trust | 0,02% | 209 299 SH | 8 de agosto de 2026 | Diario |
| ISCV · iShares Trust | 0,02% | 9 176 SH | 8 de agosto de 2026 | Diario |
| ITWO · ProShares Trust | 0,01% | 3 114 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 365 890 NS | 31 de mayo de 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 2 918 SH | 8 de agosto de 2026 | Diario |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 942 459 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,01% | 23 339 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 125 232 SH | 8 de agosto de 2026 | Diario |
| ISCG · iShares Trust | 0,01% | 7 494 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,01% | 2 435 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 20 039 NS | 30 de abril de 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 2 463 NS | 31 de mayo de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,01% | 2 102 NS | 30 de abril de 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 2 651 SH | 8 de agosto de 2026 | Diario |
| DCOR · Dimensional ETF Trust | 0,00% | 9 920 NS | 30 de abril de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 40 897 NS | 31 de mayo de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 2 346 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 30 514 NS | 30 de abril de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 62 NS | 31 de mayo de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 97 392 NS | 30 de abril de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 116 415 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 17 499 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 46 809 NS | 31 de mayo de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 11 258 NS | 30 de abril de 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 7 147 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 2 918 973 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 5 372 SH | 8 de agosto de 2026 | Diario |