PBYI Puma Biotechnology Inc - Common Stock

NASDAQ · Biotechnology · Ver en SEC EDGAR ↗
$8,81
Precio · Ago 18, 2026
Fundamentales a fecha de Ago 6, 2026

Acerca de Puma Biotechnology Inc - Common Stock Descripción general de la empresa de Wikipedia

Puma Biotechnology is a publicly traded biopharmaceutical company headquartered in Los Angeles, CA.

Leer más

Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.

Creation

Puma was founded in September 2010 by Alan Auerbach to identify and in-license compounds that were already in clinical development. This was the same business plan Auerbach had followed at Cougar Biotechnology, which he founded in 2003, and through which he in-licensed abiraterone acetate from BTG plc. Cougar further developed abiraterone before the company was sold to Johnson & Johnson in 2009. Auerbach brought many Cougar employees with him after founding Puma in 2010.

Funding for development

In August 2011 Puma licensed two drug candidates from Pfizer: neratinib (PB272) and an analog (PB357) to serve as a backup candidate.

As part of an approximately $60 million financing round in October 2011, Puma entered into a reverse merger with the shell company Innovative Acquisitions Corp., formed in 2007. In April 2012 the company's stock began trading over the counter. In October 2012 the company raised around $138 million and its shares were listed on the New York Stock Exchange.

In 2016 Puma discovered that Robert Gadimian, senior director of regulatory affairs, had twice bought and sold stock based on his knowledge of unpublished clinical trial results; Puma quickly fired him after conducting an internal investigation and reported the insider trading to the SEC.

Approval and licensing of neratinib

In March 2016 Puma held a pre-NDA meeting with the FDA in which the FDA raised concerns about the design and conduct of clinical trials that Puma had run and recommended that Puma not file the NDA with that data.

Puma did file the NDA, and in May 2017 an FDA review panel recommended that the FDA approve neratinib but raised concerns that the intended use was too broad and should be limited to people with specific mutations. The FDA's briefing document to the panel had raised concerns about the marginal benefit of the drug and the side effects. In July 2017 the FDA approved neratinib for use in preventing the return of breast cancer after treatment that included trastuzumab and without any need for genetic testing, and with warnings about the risk of severe diarrhea. U.S. sales of neratinib totaled $200.5 million in 2018.

In January 2018 an EMA committee gave a negative review to neratinib. In June 2018 this same EMA committee recommended the approval of neratinib, which received European Commission (EC) approval in September 2018.

In 2019 Puma licensed commercialization rights in Europe and part of Africa to Pierre Fabre for an upfront payment of $60 million and milestone payments that could reach $345 million. Previously, Puma licensed rights in Greater China to CANbrdige Life Sciences, rights in Israel to Medison Pharma, rights in Canada to Knight Therapeutics, rights in South East Asian to Specialised Therapeutics and rights in Latin America to Pint Pharma.

== References ==

Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗

Wikidata ↗

PBYI Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas

Precio
$8.81
Capitalización Bursátil
$448M
P/E (TTM)
14.6
BPA (TTM)
$0.61
Ingresos (TTM)
$228M
Rendimiento div.
ROE
26.5%
Deuda/Capital
0.2
Rango 52S
$4 – $9

PBYI Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista

Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA

Ingresos y Beneficio Neto $228M
9-point trend, +724.9%
2017-12-31 2025-12-31
BPA $0.61
6-point trend, +140.1%
2020-12-31 2025-12-31
Flujo de caja libre $42M
8-point trend, +128.6%
2016-12-31 2025-12-31
Márgenes 13.6%

Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?

Métrica
Tendencia a 5 años
PBYI
Mediana de Pares
P/E (TTM)
5-point trend, +244.5%
14.6
17.4
P/S (TTM) (P/V (TTM))
5-point trend, +172.8%
2.0
52.3
P/B (P/C)
5-point trend, +104.6%
3.4
4.8
EV / EBITDA
5-point trend, -94.3%
10.0
Price / FCF (Precio / FCF)
5-point trend, +21.8%
10.7

Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC

Métrica
Tendencia a 5 años
PBYI
Mediana de Pares
Operating Margin (Margen Operativo)
5-point trend, +3102.0%
16.3%
Net Profit Margin (Margen de Beneficio Neto)
5-point trend, +218.3%
13.6%
-670.1%
ROA
5-point trend, +217.1%
14.5%
-41.1%
ROE
5-point trend, -93.9%
26.5%
-52.6%
ROIC
5-point trend, +1437.7%
21.2%

Salud financiera Deuda, liquidez, solvencia — solidez del balance general

Métrica
Tendencia a 5 años
PBYI
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
5-point trend, +100.4%
0.2
Current Ratio (Ratio corriente)
5-point trend, +56.7%
2.0
7.7
Quick Ratio (Ratio Rápido)
5-point trend, +77.9%
1.9

Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años

Métrica
Tendencia a 5 años
PBYI
Mediana de Pares
Revenue YoY (Ingresos interanuales)
5-point trend, -9.8%
-0.91%
Revenue CAGR 3Y (Ingresos CAGR 3A)
5-point trend, -9.8%
0.05%
Revenue CAGR 5Y (Ingresos CAGR 5A)
5-point trend, -9.8%
0.29%
EPS YoY (EPS interanual)
5-point trend, +184.7%
-1.6%
Net Income YoY (Beneficio Neto interanual)
5-point trend, +206.8%
2.8%

Métricas por acción BPA, valor contable por acción, flujo de caja por acción, dividendo por acción

Métrica
Tendencia a 5 años
PBYI
Mediana de Pares
EPS (Diluted) (BPA (Diluido))
5-point trend, +184.7%
$0.61

Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar

Métrica
Tendencia a 5 años
PBYI
Mediana de Pares

PBYI Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista

VENTA 6 analistas
  • Compra fuerte 0 0,0%
  • Compra 0 0,0%
  • Mantener 3 50,0%
  • Venta 1 16,7%
  • Venta fuerte 2 33,3%

Precio objetivo a 12 meses

1 analistas · 2026-08-18
Objetivo mediano $6.00 -31,9%
Objetivo medio $6.00 -31,9%

Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados

Sorpresa Media
0.07%
Período EPS Actual EPS est. Sorpresa
30 de junio de 2026 $0.16 $0.04 0.12%
31 de marzo de 2026 $-0.07 $-0.13 0.06%
31 de diciembre de 2025 $0.26 $0.23 0.03%
30 de septiembre de 2025 $0.17 $0.05 0.12%
30 de junio de 2025 $0.12 $0.10 0.02%
31 de marzo de 2025 $0.06 $-0.02 0.08%

Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector

Ticker Capitalización Bursátil P/E Ingresos interanuales Margen Neto ROE Margen Bruto
PBYI $300M 9.8 -0.91% 13.6% 26.5%
CABA $220M -1.0 -115.5%
QTTB $43M 1.4 55.5% 200.3%
OCGN $422M -5.6 8.8% -1537.4% 1488.8%
LRMR $317M -2.2 -167.4%
RZLT $388M -4.6 -56.9%
BNTC $307M -11.1 -43.8%
EDIT $201M -1.1 25.4% -395.0% -688.8%
CMPX $958M -45.9%
PROK 1075.0% -7725.2% 6.9%

Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja

Estado de resultados 17
Datos anuales de Estado de resultados para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Revenue 9-point trend, +724.9% $228M $230M $236M $228M $253M $225M $272M $251M $28M
Cost of Revenue 9-point trend, +943.7% $58M $64M $63M $55M $64M $39M $37M $35M $6M
R&D Expense 5-point trend, -65.4% · · · · $72M $98M $133M $165M $208M
SG&A Expense 9-point trend, -33.6% $71M $80M $90M $90M $116M $118M $142M $146M $107M
Operating Expenses 9-point trend, -40.3% $191M $200M $203M $204M $252M $256M $311M $346M $320M
Operating Income 9-point trend, +112.8% $37M $31M $33M $24M $1M $-30M $-39M $-95M $-292M
Interest Expense 7-point trend, +1751.4% · · $13M $12M $13M $14M $15M $11M $720.0K
Interest Income 9-point trend, +224.7% $4M $5M $3M $813.0K $160.0K $489.0K $3M $2M $1M
Other Non-op 9-point trend, +1116.8% $1M $862.0K $759.0K $-28.0K $292.0K $367.0K $128.0K $-714.0K $-101.0K
Pretax Income 8-point trend, +131.5% $36M $24M $23M $457.0K $-29M $-60M $-76M $-114M ·
Income Tax 9-point trend, +4671000.00 $5M $-6M $1M $455.0K $324.0K $207.0K $53.0K $17.0K $0
Net Income 9-point trend, +110.7% $31M $30M $22M $2.0K $-29M $-60M $-76M $-114M $-292M
EPS (Basic) 7-point trend, +100.0% $0.62 $0.62 $0.46 $0.00 $-0.72 $-1.52 $-75595.00 · ·
EPS (Diluted) 6-point trend, +140.1% $0.61 $0.62 $0.45 $0.00 $-0.72 $-1.52 · · ·
Shares (Basic) 6-point trend, +26.4% 50,011,485 48,648,701 47,134,331 44,674,501 40,638,852 39,576,107 · · ·
Shares (Diluted) 6-point trend, +28.0% 50,653,283 49,100,433 47,550,852 44,929,998 40,638,852 39,576,107 · · ·
EBITDA 9-point trend, +112.8% $37M $31M $33M $24M $1M $-30M $-39M $-95M $-292M
Balance general 26
Datos anuales de Balance general para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Cash & Equivalents 9-point trend, -63.7% $30M $69M $85M $76M $63M $85M $60M $108M $82M
Short-term Investments 8-point trend, +19.1% $68M $32M $11M $5M $19M $8M $52M $57M ·
Receivables 9-point trend, +454.9% $54M $32M $48M $40M $33M $26M $29M $21M $10M
Inventory 9-point trend, +171.8% $6M $9M $7M $5M $7M $3M $3M $3M $2M
Prepaid Expense 9-point trend, -72.0% $4M $6M $4M $6M $9M $11M $13M $12M $13M
Other Current Assets 8-point trend, -85.7% $256.0K $91.0K $912.0K $2M $447.0K $4M $323.0K $2M ·
Current Assets 9-point trend, +52.9% $163M $148M $156M $134M $140M $146M $166M $203M $106M
PP&E (Net) 9-point trend, -95.8% $187.0K $515.0K $855.0K $1M $2M $2M $3M $4M $4M
PP&E (Gross) 9-point trend, -43.9% $5M $8M $9M $9M $9M $9M $9M $9M $9M
Accum. Depreciation 9-point trend, +13.2% $5M $8M $8M $7M $7M $6M $6M $5M $4M
Intangibles 9-point trend, -14.4% $41M $51M $61M $71M $66M $74M $40M $44M $48M
Total Assets 9-point trend, +30.7% $216M $213M $231M $222M $227M $244M $235M $259M $166M
Accounts Payable 9-point trend, -81.7% $5M $6M $7M $6M $11M $12M $19M $21M $28M
Accrued Liabilities 9-point trend, +63.2% $50M $37M $53M $53M $93M $61M $69M $46M $31M
Current Liabilities 9-point trend, +39.3% $81M $96M $99M $77M $110M $114M $91M $67M $58M
Capital Leases 7-point trend, -79.2% $5M $1M $7M $12M $16M $20M $23M · ·
Other Non-current Liabilities 3-point trend, -100.0% $0 $121.0K $121.0K · · · · · ·
Total Liabilities 9-point trend, -23.4% $86M $121M $177M $200M $229M $250M $217M $225M $112M
Long-term Debt 9-point trend, -53.2% $23M $68M $102M $102M $102M $84M $95M $152M $48M
Total Debt 6-point trend, -77.1% $23M $67M $100M $98M $97M $98M · · ·
Common Stock 9-point trend, +25.0% $5.0K $5.0K $5.0K $5.0K $4.0K $4.0K $4.0K $4.0K $4.0K
Retained Earnings 9-point trend, -17.9% $-1.28B $-1.31B $-1.35B $-1.37B $-1.37B $-1.34B $-1.28B $-1.20B $-1.09B
AOCI 8-point trend, +400.0% $36.0K $6.0K $-4.0K $0 $-2.0K $0 $62.0K $-12.0K ·
Stockholders' Equity 9-point trend, +144.5% $130M $92M $53M $22M $-2M $-6M $17M $34M $53M
Liabilities + Equity 9-point trend, +30.7% $216M $213M $231M $222M $227M $244M $235M $259M $166M
Shares Outstanding 9-point trend, +34.1% 50,408,023 49,105,834 47,646,787 46,345,660 41,175,507 40,086,387 39,203,304 38,325,037 37,594,851
Flujo de Efectivo 14
Datos anuales de Flujo de Efectivo para PBYI
Métrica Tendencia 202520242023202220212020201920182017
D&A 9-point trend, +289.1% $11M $12M $12M $10M $11M $10M $8M $7M $3M
Stock-based Comp 9-point trend, -93.6% $7M $8M $10M $12M $33M $37M $57M $87M $109M
Deferred Tax 4-point trend, +3245000.00 $3M $-7M $0 $0 · · · · ·
Amort. of Intangibles 9-point trend, +506.2% $10M $10M $8M $8M $8M $6M $4M $4M $2M
Operating Cash Flow 9-point trend, +124.2% $42M $39M $27M $-16M $21M $773.0K $22M $-24M $-172M
CapEx 9-point trend, -83.5% $71.0K $56.0K $140.0K $0 $0 $46.0K $306.0K $439.0K $431.0K
Investing Cash Flow 9-point trend, -134.4% $-36M $-20M $-19M $7M $-11M $33M $5M $-58M $-15M
Debt Issued 3-point trend, -50.0% · · · · · · $25M $105M $50M
Net Debt Issued 3-point trend, -50.0% · · · · · · $25M $105M $50M
Financing Cash Flow 9-point trend, -160.2% $-45M $-34M $0 $12M $-32M $-10M $-67M $108M $75M
Net Change in Cash 9-point trend, +64.9% $-40M $-15M $8M $4M $-22M $24M $-40M $27M $-113M
Taxes Paid $1M · · · · · · · ·
Free Cash Flow 7-point trend, +124.1% $42M $39M $27M $-16M $21M · · $-25M $-173M
Levered FCF 3-point trend, +84.1% · · $14M $-16M $8M · · · ·
Rentabilidad 7
Datos anuales de Rentabilidad para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Operating Margin 9-point trend, +101.5% 16.3% 13.4% 13.9% 10.4% 0.51% -13.5% -14.4% -37.7% -1056.1%
Net Margin 9-point trend, +101.3% 13.6% 13.1% 9.2% 0.00% -11.5% -26.7% -27.8% -45.2% -1054.6%
Pretax Margin 6-point trend, +159.0% 15.7% 10.5% 9.6% 0.20% -11.4% -26.6% · · ·
EBITDA Margin 9-point trend, +101.5% 16.3% 13.4% 13.9% 10.4% 0.51% -13.5% -14.4% -37.7% -1056.1%
ROA 9-point trend, +110.4% 14.5% 13.6% 9.5% 0.00% -12.4% -25.0% -30.6% -53.5% -139.6%
ROE 9-point trend, +111.9% 26.5% 37.1% 46.8% 0.01% 435.8% 1873.7% -436.4% -283.2% -221.9%
ROIC 6-point trend, +164.2% 21.2% 24.4% 20.3% 0.09% 1.4% -33.0% · · ·
Liquidez y Solvencia 5
Datos anuales de Liquidez y Solvencia para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Current Ratio 9-point trend, +9.8% 2.0 1.5 1.6 1.7 1.3 1.3 1.8 3.0 1.8
Quick Ratio 9-point trend, +18.8% 1.9 1.4 1.4 1.6 1.0 1.0 1.5 2.8 1.6
Debt / Equity 6-point trend, +101.0% 0.2 0.7 1.9 4.5 -39.7 -16.5 · · ·
LT Debt / Equity 6-point trend, +100.0% 0.0 0.2 1.2 4.5 -39.7 -14.1 · · ·
Interest Coverage 7-point trend, +100.6% · · 2.4 2.0 0.1 -2.2 -2.6 -8.6 -406.1
Eficiencia 3
Datos anuales de Eficiencia para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Asset Turnover 9-point trend, +702.9% 1.1 1.0 1.0 1.0 1.1 0.9 1.1 1.2 0.1
Inventory Turnover 7-point trend, +48.7% 8.2 8.2 10.8 9.5 12.1 · · 14.9 5.5
Receivables Turnover 9-point trend, -6.9% 5.3 5.8 5.3 6.3 8.7 8.3 11.0 16.5 5.7
Por Acción 5
Datos anuales de Por Acción para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Book Value / Share 9-point trend, +82.4% $2.59 $1.88 $1.12 $0.52 $-0.06 $-0.15 $0.45 $0.90 $1.42
Revenue / Share 4-point trend, -11.2% $4.51 $4.69 $4.96 $5.08 · · · · ·
Cash Flow / Share 4-point trend, +334.3% $0.83 $0.79 $0.57 $-0.35 · · · · ·
Cash / Share 9-point trend, -72.9% $0.59 $1.41 $1.78 $1.85 $1.57 $2.13 $1.53 $2.83 $2.17
EPS (TTM) 6-point trend, +140.1% $0.61 $0.62 $0.45 $0.00 $-0.72 $-1.52 · · ·
Tasas de Crecimiento 6
Datos anuales de Tasas de Crecimiento para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Revenue YoY 5-point trend, -107.3% -0.91% -2.2% 3.3% -9.9% 12.5% · · · ·
Revenue CAGR 3Y 3-point trend, -96.8% 0.05% -3.1% 1.5% · · · · · ·
Revenue CAGR 5Y 0.29% · · · · · · · ·
EPS YoY 2-point trend, -104.3% -1.6% 37.8% · · · · · · ·
Net Income YoY 3-point trend, -100.0% 2.8% 40.2% 1079450.0% · · · · · ·
Net Income CAGR 3Y 2396.3% · · · · · · · ·
Valoración (TTM) 14
Datos anuales de Valoración (TTM) para PBYI
Métrica Tendencia 202520242023202220212020201920182017
Revenue TTM 9-point trend, +724.9% $228M $230M $236M $228M $253M $225M $272M $251M $28M
Net Income TTM 9-point trend, +110.7% $31M $30M $22M $2.0K $-29M $-60M $-76M $-114M $-292M
Market Cap 9-point trend, -91.9% $300M $150M $206M $174M $122M $411M $343M $780M $3.72B
Enterprise Value 6-point trend, -46.0% $225M $116M $210M $191M $137M $416M · · ·
P/E 5-point trend, +244.5% 9.8 4.9 9.6 · -4.2 -6.8 · · ·
P/S 9-point trend, -99.0% 1.3 0.6 0.9 0.8 0.5 1.8 1.3 3.1 134.2
P/B 9-point trend, -96.7% 2.3 1.6 3.9 8.1 -49.8 -69.1 19.6 22.7 69.7
P / Tangible Book 2-point trend, -7.7% 3.4 3.7 · · · · · · ·
P / Cash Flow 9-point trend, +133.3% 7.2 3.8 7.6 -11.0 5.9 532.1 15.3 -32.4 -21.5
P / FCF 7-point trend, +133.4% 7.2 3.9 7.7 -11.0 5.9 · · -31.8 -21.5
EV / EBITDA 6-point trend, +144.0% 6.0 3.7 6.4 8.1 106.1 -13.7 · · ·
EV / FCF 5-point trend, -18.7% 5.4 3.0 7.8 -12.1 6.6 · · · ·
EV / Revenue 6-point trend, -46.7% 1.0 0.5 0.9 0.8 0.5 1.8 · · ·
Earnings Yield 6-point trend, +169.2% 10.2% 20.3% 10.4% 0.00% -23.7% -14.8% · · ·

Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años

Estado de resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ingresos $228M$230M$236M$228M$253M
Margen Operativo % 16.3%13.4%13.9%10.4%0.51%
Beneficio neto $31M$30M$22M$2.0K$-29M
EPS Diluido $0.61$0.62$0.45$0.00$-0.72
Balance general
2025-12-312024-12-312023-12-312022-12-312021-12-31
Deuda / Patrimonio 0.20.71.94.5-39.7
Ratio corriente 2.01.51.61.71.3
Ratio Rápido 1.91.41.41.61.0
Flujo de Efectivo
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flujo de caja libre $42M$39M$27M$-16M$21M

Mis Métricas Tu lista de seguimiento personal — filas seleccionadas de Fundamentales Completos

📊

Elige las métricas que te importan — haz clic en el ➕ junto a cualquier fila en Fundamentales Completos arriba.

Tu selección se guarda y te sigue en todos los tickers.

Propietarios institucionales (13F) 173 declarantes · $239.8M total · A fecha de 30 de junio de 2026

Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.

Actividad institucional — Q2 2026 vs trimestre anterior
Nuevas posiciones Posiciones cerradas Aumentado Disminuido Cambio neto de acciones
28 (+2 vs trimestre anterior) 15 (-2 vs trimestre anterior) 56 (+1 vs trimestre anterior) 47 (+7 vs trimestre anterior) +4.1M

Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.

Institución Valor Acciones % de 13F rastreadas Tipo
ACORN CAPITAL ADVISORS, LLC $33 504 835 4 131 299 13,97% Acciones
VANGUARD GROUP INC $21 011 306 3 531 312 8,76% Acciones
AMERICAN CENTURY COMPANIES INC $18 815 168 2 319 996 7,85% Acciones
RENAISSANCE TECHNOLOGIES LLC $14 891 687 1 836 213 6,21% Acciones
VANGUARD CAPITAL MANAGEMENT LLC $14 887 065 1 835 643 6,21% Acciones
VANGUARD PORTFOLIO MANAGEMENT LLC $14 805 608 1 825 599 6,18% Acciones
DIMENSIONAL FUND ADVISORS LP $11 407 283 1 406 570 4,76% Acciones
GEODE CAPITAL MANAGEMENT, LLC $9 618 136 1 185 702 4,01% Acciones
O'SHAUGHNESSY ASSET MANAGEMENT, LLC $9 113 880 1 123 783 3,80% Acciones
STATE STREET CORP $7 722 058 952 165 3,22% Acciones
KENNEDY CAPITAL MANAGEMENT LLC $7 082 082 873 253 2,95% Acciones
BRIDGEWAY CAPITAL MANAGEMENT, LLC $6 420 006 791 616 2,68% Acciones
RITHOLTZ WEALTH MANAGEMENT $6 080 862 749 798 2,54% Acciones
Connor, Clark & Lunn Investment Management Ltd. $5 214 292 642 946 2,17% Acciones
MILLENNIUM MANAGEMENT LLC $4 884 166 602 240 2,04% Acciones
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $4 318 170 532 450 1,80% Acciones
GLOBEFLEX CAPITAL L P $3 104 565 382 807 1,29% Acciones
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $2 506 850 309 106 1,05% Acciones
D. E. Shaw & Co., Inc. $2 300 377 283 647 0,96% Acciones
Russell Investments Group, Ltd. $2 207 323 272 173 0,92% Acciones
VANGUARD FIDUCIARY TRUST CO $2 182 158 269 070 0,91% Acciones
FEDERATED HERMES, INC. $2 033 712 250 766 0,85% Acciones
Empowered Funds, LLC $1 786 763 220 316 0,75% Acciones
PANAGORA ASSET MANAGEMENT INC $1 764 290 217 545 0,74% Acciones
GOLDMAN SACHS GROUP INC $1 758 256 216 801 0,73% Acciones
FMR LLC $1 708 274 210 638 0,71% Acciones
PRUDENTIAL FINANCIAL INC $1 600 095 197 299 0,67% Acciones
STATE OF WISCONSIN INVESTMENT BOARD $1 526 562 188 232 0,64% Acciones
Prospera Financial Services Inc $1 287 530 158 762 0,54% Acciones
Haven Private, LLC $1 203 913 148 448 0,50% Acciones
TWO SIGMA INVESTMENTS, LP $1 140 161 140 587 0,48% Acciones
BlackRock, Inc. $1 134 784 139 924 0,47% Acciones
FIRST TRUST ADVISORS LP $1 055 970 130 206 0,44% Acciones
Bank of New York Mellon Corp $1 048 964 129 342 0,44% Acciones
Round Rock Advisors LLC $1 045 476 128 912 0,44% Acciones
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1 040 051 128 243 0,43% Acciones
STRS OHIO $686 106 84 600 0,29% Acciones
CANADA PENSION PLAN INVESTMENT BOARD $596 085 73 500 0,25% Acciones
Trexquant Investment LP $585 729 72 223 0,24% Acciones
Vise Technologies, Inc. $584 163 72 030 0,24% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $520 662 64 200 0,22% Opción de compra
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $497 000 61 255 0,21% Acciones
OpenArc Corporate Advisory, LLC $482 472 59 491 0,20% Acciones
RHUMBLINE ADVISERS $466 397 57 510 0,19% Acciones
TWO SIGMA ADVISERS, LP $423 045 71 100 0,18% Acciones
D'Orazio & Associates, Inc. $394 795 48 680 0,16% Acciones
Vanguard Global Advisers, LLC $375 225 46 267 0,16% Acciones
DEUTSCHE BANK AG\ $350 287 43 192 0,15% Acciones
Man Group plc $336 614 41 506 0,14% Acciones
WELLINGTON MANAGEMENT GROUP LLP $333 240 41 090 0,14% Acciones
WINTON GROUP Ltd $328 528 40 509 0,14% Acciones
XTX Topco Ltd $326 801 40 296 0,14% Acciones
State of Wyoming $323 046 39 833 0,13% Acciones
WELLS FARGO & COMPANY/MN $304 977 37 605 0,13% Acciones
EntryPoint Capital, LLC $303 200 37 386 0,13% Acciones
Baron Wealth Management LLC $294 977 36 372 0,12% Acciones
Creative Planning $289 827 35 737 0,12% Acciones
LPL Financial LLC $280 095 34 537 0,12% Acciones
Universal- Beteiligungs- und Servicegesellschaft mbH $279 673 34 485 0,12% Acciones
BANK OF AMERICA CORP /DE/ $257 468 31 747 0,11% Acciones
Kathmere Capital Management, LLC $252 805 31 172 0,11% Acciones
FRANKLIN RESOURCES INC $242 165 29 860 0,10% Acciones
ENVESTNET ASSET MANAGEMENT INC $236 731 29 190 0,10% Acciones
Y-Intercept (Hong Kong) Ltd $212 660 26 222 0,09% Acciones
MARTINGALE ASSET MANAGEMENT L P $205 703 25 364 0,09% Acciones
Metis Global Partners, LLC $204 891 25 264 0,09% Acciones
MetLife Investment Management, LLC $201 720 24 873 0,08% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $195 451 24 100 0,08% Opción de venta
C2C Wealth Management, LLC $191 558 23 620 0,08% Acciones
Nuveen, LLC $187 982 23 179 0,08% Acciones
PRELUDE CAPITAL MANAGEMENT, LLC $174 754 21 548 0,07% Acciones
One Wealth Advisors, LLC $170 951 21 079 0,07% Acciones
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $165 306 20 383 0,07% Acciones
CITIGROUP INC $154 990 19 111 0,06% Acciones
BAILARD, INC. $146 791 18 100 0,06% Acciones
Invesco Ltd. $142 493 17 570 0,06% Acciones
JANE STREET GROUP, LLC $141 925 17 500 0,06% Opción de compra
Spark Investment Management LLC $137 870 17 000 0,06% Acciones
MORGAN STANLEY $137 416 16 944 0,06% Acciones
ALLIANCEBERNSTEIN L.P. $136 490 21 360 0,06% Acciones
Brandywine Global Investment Management, LLC $129 710 21 800 0,05% Acciones
Police & Firemen's Retirement System of New Jersey $127 481 15 719 0,05% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $125 510 15 476 0,05% Acciones
Lido Advisors, LLC $122 015 15 045 0,05% Acciones
Mariner, LLC $120 593 14 869 0,05% Acciones
Caprock Group, LLC $112 421 13 862 0,05% Acciones
PERKINS CAPITAL MANAGEMENT INC $108 674 13 400 0,05% Acciones
TOCQUEVILLE ASSET MANAGEMENT L.P. $107 960 13 312 0,05% Acciones
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $105 624 13 203 0,04% Acciones
UBS Group AG $99 923 12 321 0,04% Acciones
MANUFACTURERS LIFE INSURANCE COMPANY, THE $97 774 12 056 0,04% Acciones
CWM, LLC $97 531 15 263 0,04% Acciones
R Squared Ltd $97 247 11 991 0,04% Acciones
Abel Hall, LLC $93 427 11 520 0,04% Acciones
IEQ CAPITAL, LLC $86 542 10 671 0,04% Acciones
Williams & Novak, LLC $85 066 10 489 0,04% Acciones
Vanguard Personalized Indexing Management, LLC $84 409 10 408 0,04% Acciones
Ethic Inc. $83 290 10 270 0,03% Acciones
AQR CAPITAL MANAGEMENT LLC $83 136 10 251 0,03% Acciones
INTECH INVESTMENT MANAGEMENT LLC $82 803 10 210 0,03% Acciones

Informantes de la empresa 24 insiders · 10 directivos · 12 consejeros

Insider Rol Última actividad Acciones en propiedad Compras 12m Ventas 12m Neto 12m
Alan H Auerbach President and CEO 6 de julio de 2026 S 7 261 671 0 1 $-363 919
Maximo F Nougues Chief Financial Officer 6 de julio de 2026 S 230 637 0 1 $-77 528
Douglas M Hunt The Reporting Person is the Senior Vice President of Regulatory Affairs of the Issuer. 6 de julio de 2026 S 196 841 0 1 $-69 880
Alvin F Wong Chief Scientific Officer 17 de junio de 2021 A 0 0 $0
Richard Paul Bryce Title of Reporting Person: Chief Medical and Scientific Officer 5 de abril de 2021 S 121 662 0 0 $0
Jeffrey Jerome Ludwig Chief Commercial Officer 17 de febrero de 2021 A 36 069 0 0 $0
Steven Lo Chief Commercial Officer 22 de julio de 2019 S 19 557 0 0 $0
Charles R Eyler Title of Reporting Person: Senior Vice President, Finance and Administration and Treasurer 4 de febrero de 2019 S 31 957 0 0 $0
Robert Charnas The Reporting Person is the Senior Vice President of Regulatory Affairs and Project Management of the Issuer. 16 de febrero de 2017 A 26 453 0 0 $0
Richard Benton Phillips The Reporting Person is the Interim Head of Regulatory Affairs, Quality Assurance and Pharmacovigilance of the Issuer. 15 de abril de 2016 A 0 0 $0
Brian M Stuglik Consejero 12 de junio de 2026 S 113 858 0 1 $-58 320
Allison Dorval Consejero 12 de junio de 2026 S 90 780 0 1 $-83 592
Adrian Senderowicz Consejero 12 de junio de 2026 S 27 000 0 1 $-194 400
Troy Edward Wilson Consejero 12 de junio de 2026 S 59 750 0 1 $-77 760
Jay M Moyes Consejero 12 de junio de 2026 S 58 322 0 1 $-158 840
Alessandra Cesano Consejero 11 de junio de 2026 A 68 850 0 0 $0
MILLER MICHAEL PATRICK Consejero 11 de junio de 2026 A 81 000 0 0 $0
Ann Calby Miller Consejero 15 de junio de 2021 A 40 732 0 0 $0
Hugh O'Dowd Consejero 9 de junio de 2020 A 25 748 0 0 $0
Frank Zavrl Consejero 9 de junio de 2020 A 50 993 0 0 $0
Thomas Malley Consejero 15 de diciembre de 2014 A 156 551 0 0 $0
Faraaz Siddiqi 4 de octubre de 2011 D 0 0 0 $0
Kapil Munjal 4 de octubre de 2011 D 0 0 0 $0
Robert Andrew Johnson 4 de octubre de 2011 D 0 0 0 $0

Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto

Activistas y propietarios del %+ 5 7 tenencias

Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.

Declarante Presentado Participación Estado Propósito Presentación
Alan H. Auerbach ×6 presentaciones 13 de diciembre de 2022 Presentación inicial SEC
Kapil Munjal 2) 4 de octubre de 2011 Presentación inicial SEC
Faraaz Siddiqi 2) 4 de octubre de 2011 Presentación inicial SEC
Robert Johnson 2) 4 de octubre de 2011 Presentación inicial SEC
Robert Johnson 21 de noviembre de 2007 Presentación inicial SEC
Persona informante no revelada 19 de noviembre de 2007 Presentación inicial SEC
Faraaz Siddiqi 19 de noviembre de 2007 Presentación inicial SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Propiedad de ETFs Mantenido por 36 ETFs

El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.

Fondo Ponderación Unidades A fecha de Fuente
ROSC · Lattice Strategies Trust 0,72% 52 608 NS 30 de abril de 2026 N-PORT
DWAS · Invesco Exchange-Traded Fund Trust … 0,46% 233 908 SH 8 de agosto de 2026 Diario
IWC · iShares Trust 0,08% 150 797 SH 8 de agosto de 2026 Diario
VFQY · VANGUARD WELLINGTON FUND 0,06% 34 260 SH 8 de agosto de 2026 Diario
AVUV · AMERICAN CENTURY ETF TRUST 0,05% 1 924 360 NS 31 de mayo de 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,04% 55 680 NS 31 de mayo de 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0,03% 2 746 SH 8 de agosto de 2026 Diario
AVSC · AMERICAN CENTURY ETF TRUST 0,02% 95 559 NS 31 de mayo de 2026 N-PORT
VTWV · VANGUARD SCOTTSDALE FUNDS 0,02% 32 358 SH 8 de agosto de 2026 Diario
IWN · iShares Trust 0,02% 356 623 SH 8 de agosto de 2026 Diario
BIB · ProShares Trust 0,02% 1 879 NS 31 de mayo de 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,02% 55 064 SH 8 de agosto de 2026 Diario
IWM · iShares Trust 0,01% 1 153 241 SH 8 de agosto de 2026 Diario
RSSL · Global X Funds 0,01% 19 123 NS 30 de abril de 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,01% 16 014 SH 8 de agosto de 2026 Diario
VTWO · VANGUARD SCOTTSDALE FUNDS 0,01% 254 380 SH 8 de agosto de 2026 Diario
DFAS · Dimensional ETF Trust 0,01% 166 672 NS 30 de abril de 2026 N-PORT
DFAT · Dimensional ETF Trust 0,01% 156 761 NS 30 de abril de 2026 N-PORT
DFSV · Dimensional ETF Trust 0,01% 82 003 NS 30 de abril de 2026 N-PORT
ITWO · ProShares Trust 0,01% 2 027 NS 31 de mayo de 2026 N-PORT
DXUV · Dimensional ETF Trust 0,01% 3 611 NS 30 de abril de 2026 N-PORT
EBI · RBB Fund Trust 0,01% 5 394 NS 31 de mayo de 2026 N-PORT
UWM · ProShares Trust 0,00% 1 585 NS 31 de mayo de 2026 N-PORT
IWO · iShares Trust 0,00% 65 370 SH 8 de agosto de 2026 Diario
URTY · ProShares Trust 0,00% 1 603 NS 31 de mayo de 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,00% 2 071 NS 31 de mayo de 2026 N-PORT
AVUS · AMERICAN CENTURY ETF TRUST 0,00% 34 919 NS 31 de mayo de 2026 N-PORT
DCOR · Dimensional ETF Trust 0,00% 6 348 NS 30 de abril de 2026 N-PORT
HDG · ProShares Trust 0,00% 40 NS 31 de mayo de 2026 N-PORT
DFAU · Dimensional ETF Trust 0,00% 9 704 NS 30 de abril de 2026 N-PORT
DFUS · Dimensional ETF Trust 0,00% 15 090 NS 30 de abril de 2026 N-PORT
DFAC · Dimensional ETF Trust 0,00% 12 376 NS 30 de abril de 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0,00% 446 899 SH 8 de agosto de 2026 Diario
VTI · VANGUARD INDEX FUNDS 0,00% 1 343 121 SH 8 de agosto de 2026 Diario
VTWG · VANGUARD SCOTTSDALE FUNDS 0,00% 7 680 SH 8 de agosto de 2026 Diario
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 2 979 SH 8 de agosto de 2026 Diario