PRLD — Propietarios institucionales (13F)
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $73 151 963 | 13 724 571 | 27,36% | Acciones |
| BAKER BROS. ADVISORS LP | $53 959 982 | 10 123 824 | 20,19% | Acciones |
| RA CAPITAL MANAGEMENT, L.P. | $34 516 451 | 6 475 882 | 12,91% | Acciones |
| Soleus Capital Management, L.P. | $18 006 755 | 3 378 378 | 6,74% | Acciones |
| Kynam Capital Management, LP | $12 872 414 | 2 415 087 | 4,82% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $10 710 342 | 2 009 445 | 4,01% | Acciones |
| BlackRock, Inc. | $9 580 681 | 1 797 501 | 3,58% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $5 435 705 | 1 019 832 | 2,03% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $5 294 657 | 993 369 | 1,98% | Acciones |
| ADAR1 Capital Management, LLC | $4 801 797 | 900 900 | 1,80% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $4 503 813 | 844 993 | 1,68% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $4 487 860 | 841 862 | 1,68% | Acciones |
| VANGUARD GROUP INC | $4 100 559 | 1 413 986 | 1,53% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4 083 286 | 766 095 | 1,53% | Acciones |
| MORGAN STANLEY | $2 685 574 | 503 860 | 1,00% | Acciones |
| STATE STREET CORP | $2 285 435 | 428 787 | 0,85% | Acciones |
| UBS Group AG | $1 699 188 | 318 797 | 0,64% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $1 518 442 | 284 886 | 0,57% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $1 498 796 | 281 200 | 0,56% | Acciones |
| NORTHERN TRUST CORP | $1 282 393 | 240 599 | 0,48% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 033 594 | 193 920 | 0,39% | Acciones |
| MARSHALL WACE, LLP | $1 016 387 | 190 692 | 0,38% | Acciones |
| TWO SIGMA ADVISERS, LP | $688 170 | 237 300 | 0,26% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $669 480 | 125 606 | 0,25% | Acciones |
| GOLDMAN SACHS GROUP INC | $644 045 | 120 834 | 0,24% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $591 630 | 111 000 | 0,22% | Opción de compra |
| Hillsdale Investment Management Inc. | $433 862 | 81 400 | 0,16% | Acciones |
| Bank of New York Mellon Corp | $363 436 | 68 187 | 0,14% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $360 425 | 67 622 | 0,13% | Acciones |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $343 785 | 64 500 | 0,13% | Acciones |
| JANE STREET GROUP, LLC | $341 653 | 64 100 | 0,13% | Opción de compra |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $339 521 | 63 700 | 0,13% | Opción de venta |
| Squarepoint Ops LLC | $317 348 | 59 540 | 0,12% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $253 569 | 47 574 | 0,09% | Acciones |
| Mariner, LLC | $241 241 | 45 261 | 0,09% | Acciones |
| Nuveen, LLC | $197 333 | 37 023 | 0,07% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $186 839 | 35 210 | 0,07% | Acciones |
| Invesco Ltd. | $185 175 | 34 742 | 0,07% | Acciones |
| Cerity Partners LLC | $175 224 | 32 875 | 0,07% | Acciones |
| State of Wyoming | $175 154 | 32 862 | 0,07% | Acciones |
| CITADEL ADVISORS LLC | $166 829 | 31 300 | 0,06% | Opción de venta |
| Graham Capital Management, L.P. | $158 674 | 29 770 | 0,06% | Acciones |
| DEUTSCHE BANK AG\ | $148 302 | 27 824 | 0,06% | Acciones |
| WELLS FARGO & COMPANY/MN | $134 982 | 25 325 | 0,05% | Acciones |
| BANK OF AMERICA CORP /DE/ | $127 254 | 23 875 | 0,05% | Acciones |
| CITADEL ADVISORS LLC | $120 213 | 22 554 | 0,04% | Acciones |
| RHUMBLINE ADVISERS | $117 649 | 22 074 | 0,04% | Acciones |
| JANE STREET GROUP, LLC | $107 133 | 20 100 | 0,04% | Opción de venta |
| Vanguard Global Advisers, LLC | $86 399 | 16 210 | 0,03% | Acciones |
| CITADEL ADVISORS LLC | $85 813 | 16 100 | 0,03% | Opción de compra |
| ExodusPoint Capital Management, LP | $82 482 | 15 475 | 0,03% | Acciones |
| BARCLAYS PLC | $77 439 | 14 529 | 0,03% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $75 686 | 14 200 | 0,03% | Acciones |
| HSBC HOLDINGS PLC | $74 403 | 13 652 | 0,03% | Acciones |
| MANGROVE PARTNERS IM, LLC | $71 166 | 13 352 | 0,03% | Acciones |
| Qube Research & Technologies Ltd | $69 876 | 13 110 | 0,03% | Acciones |
| CITIGROUP INC | $69 466 | 13 033 | 0,03% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $68 139 | 12 784 | 0,03% | Acciones |
| JPMORGAN CHASE & CO | $66 742 | 13 538 | 0,02% | Acciones |
| Spark Investment Management LLC | $56 498 | 10 600 | 0,02% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $55 922 | 10 492 | 0,02% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $36 013 | 10 530 | 0,01% | Acciones |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $34 272 | 6 430 | 0,01% | Acciones |
| FMR LLC | $30 003 | 5 629 | 0,01% | Acciones |
| STRS OHIO | $29 315 | 5 500 | 0,01% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $21 874 | 4 104 | 0,01% | Acciones |
| GROUP ONE TRADING LLC | $20 824 | 3 907 | 0,01% | Acciones |
| Legal & General Group Plc | $14 386 | 2 699 | 0,01% | Acciones |
| ROYAL BANK OF CANADA | $14 000 | 2 658 | 0,01% | Acciones |
| Ameritas Investment Partners, Inc. | $13 432 | 2 520 | 0,01% | Acciones |
| Tower Research Capital LLC (TRC) | $12 669 | 2 377 | 0,00% | Acciones |
| Russell Investments Group, Ltd. | $11 832 | 2 220 | 0,00% | Acciones |
| NISA INVESTMENT ADVISORS, LLC | $8 709 | 1 634 | 0,00% | Acciones |
| PNC Financial Services Group, Inc. | $6 242 | 1 171 | 0,00% | Acciones |
| Quarry LP | $4 024 | 755 | 0,00% | Acciones |
| ACADIAN ASSET MANAGEMENT LLC | $3 253 | 611 359 | 0,00% | Acciones |
| CWM, LLC | $1 960 | 573 | 0,00% | Acciones |
| Fortitude Family Office, LLC | $1 226 | 230 | 0,00% | Acciones |
| Sterling Capital Management LLC | $517 | 97 | 0,00% | Acciones |
| PRICE T ROWE ASSOCIATES INC /MD/ | $122 | 22 758 | 0,00% | Acciones |
| SBI Securities Co., Ltd. | $117 | 22 | 0,00% | Acciones |
| Caitong International Asset Management Co., Ltd | $96 | 18 | 0,00% | Acciones |
| GSA CAPITAL PARTNERS LLP | $68 | 12 672 | 0,00% | Acciones |
| Optiver Holding B.V. | $21 | 4 | 0,00% | Acciones |