PTGX Protagonist Therapeutics, Inc. - Common Stock
PTGX Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
PTGX Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
PTGX Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 7 35,0%
- Compra 11 55,0%
- Mantener 2 10,0%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
13 analistas · 2026-08-16Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $2.29 | $2.12 | 0.17% |
| 31 de marzo de 2026 | $0.05 | $-0.54 | 0.59% |
| 31 de diciembre de 2025 | $-0.69 | $-0.50 | -0.19% |
| 30 de septiembre de 2025 | $-0.62 | $-0.65 | 0.03% |
| 30 de junio de 2025 | $-0.55 | $-0.59 | 0.04% |
| 31 de marzo de 2025 | $-0.19 | $-0.24 | 0.05% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| PTGX | $5.47B | -42.6 | -89.4% | -282.8% | -20.3% | — |
| CYTK | $7.81B | -9.7 | 376.6% | -891.6% | 152.7% | — |
| PRAX | $7.43B | -21.9 | 249.5% | — | -47.3% | — |
| SMMT | $13.56B | -12.1 | — | — | -235.1% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
| APGE | $5.16B | -17.9 | — | — | — | — |
| KRYS | $7.20B | 36.0 | 33.9% | 52.6% | 18.1% | — |
| IONS | $12.92B | -33.2 | — | — | -68.1% | — |
| SYRE | $2.56B | 10.1 | -62.0% | — | -26.5% | — |
| PCVX | $6.05B | -8.2 | — | — | -26.6% | — |
| IMVT | $5.07B | -9.0 | 229.2% | — | -73.7% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $46M | $434M | $60M | $27M | $27M | $29M | $231.0K | $31M | $20M | |
| R&D Expense | $159M | $138M | $120M | $126M | $126M | $75M | $65M | $59M | $46M | |
| SG&A Expense | $45M | $43M | $33M | $32M | $27M | $19M | $16M | $14M | $12M | |
| Operating Expenses | $204M | $182M | $154M | $158M | $153M | $93M | $81M | $73M | $58M | |
| Operating Income | $-158M | $253M | $-94M | $-131M | $-126M | $-65M | $-81M | $-42M | $-38M | |
| Interest Expense | · | · | · | · | · | $598.0K | $169.0K | · | · | |
| Interest Income | $29M | $26M | $15M | $4M | $443.0K | $900.0K | $3M | $3M | $948.0K | |
| Other Non-op | $27.0K | $250.0K | $-201.0K | $-80.0K | $-149.0K | $-46.0K | $-1.0K | $-20.0K | $-8.0K | |
| Pretax Income | $-129M | $279M | $-79M | $-127M | $-126M | $-65M | $-78M | $-40M | $-37M | |
| Income Tax | $838.0K | $4M | $0 | $0 | $0 | $1M | $-691.0K | $-799.0K | $0 | |
| Net Income | $-130M | $275M | $-79M | $-127M | $-126M | $-66M | $-77M | $-39M | $-37M | |
| EPS (Basic) | $-2.05 | $4.47 | $-1.39 | $-2.60 | $-2.71 | $-1.92 | · | · | · | |
| EPS (Diluted) | $-2.05 | $4.23 | $-1.39 | $-2.60 | $-2.71 | $-1.92 | · | · | · | |
| Shares (Basic) | 63,573,048 | 61,566,989 | 56,763,559 | 49,042,232 | 46,322,910 | 34,396,446 | · | · | · | |
| Shares (Diluted) | 63,573,048 | 65,077,722 | 56,763,559 | 49,042,232 | 46,322,910 | 34,396,446 | · | · | · | |
| EBITDA | $-157M | $254M | $-93M | $-130M | $-125M | $-64M | $-80M | $-42M | $-37M |
Balance general 22
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $128M | $97M | $187M | $126M | $124M | $117M | $33M | $82M | $106M | |
| Short-term Investments | $439M | $322M | $155M | $112M | $203M | $188M | $100M | $47M | $38M | |
| Prepaid Expense | $10M | $8M | $4M | $6M | $9M | $6M | $6M | $3M | $4M | |
| Other Current Assets | $10.0K | $248.0K | $76.0K | $42.0K | · | · | · | · | $1M | |
| Current Assets | $578M | $592M | $356M | $243M | $341M | $316M | $145M | $138M | $151M | |
| PP&E (Net) | $4M | $3M | $1M | $2M | $2M | $1M | $2M | $861.0K | $879.0K | |
| PP&E (Gross) | $12M | $10M | $7M | $7M | $6M | $5M | $4M | $3M | $2M | |
| Accum. Depreciation | $8M | $7M | $6M | $5M | $4M | $3M | $3M | $2M | $2M | |
| Total Assets | $668M | $745M | $358M | $248M | $348M | $324M | $155M | $139M | $164M | |
| Accounts Payable | $5M | $2M | $772.0K | $4M | $2M | $3M | $3M | $6M | $1M | |
| Accrued Liabilities | $28M | $24M | $19M | $25M | $38M | $18M | $12M | $11M | $10M | |
| Current Liabilities | $45M | $47M | $21M | $31M | $44M | $40M | $35M | $26M | $43M | |
| Capital Leases | $8M | $10M | · | $1M | $4M | $4M | $6M | · | · | |
| Other Non-current Liabilities | · | · | · | · | · | $121.0K | · | · | · | |
| Total Liabilities | $53M | $69M | $21M | $32M | $48M | $45M | $75M | $27M | $43M | |
| Long-term Debt | · | · | · | · | · | · | $10M | · | · | |
| Common Stock | $1.0K | $1.0K | $1.0K | · | · | · | · | · | $0 | |
| Retained Earnings | $-471M | $-341M | $-616M | $-537M | $-409M | $-284M | $-218M | $-140M | $-102M | |
| AOCI | $641.0K | $-82.0K | $-105.0K | $-359.0K | $-299.0K | $28.0K | $-221.0K | $-233.0K | $-6.0K | |
| Stockholders' Equity | $615M | $675M | $337M | $216M | $300M | $280M | $80M | $113M | $121M | |
| Liabilities + Equity | $668M | $745M | $358M | $248M | $348M | $324M | $155M | $139M | $164M | |
| Shares Outstanding | 62,577,897 | 61,035,139 | 57,708,613 | 49,339,252 | 47,838,330 | 43,745,465 | 27,217,649 | 23,187,219 | 21,088,306 |
Flujo de Efectivo 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $1M | $826.0K | $977.0K | $1M | $813.0K | $948.0K | $732.0K | $527.0K | $406.0K | |
| Stock-based Comp | $46M | $38M | $29M | $24M | $16M | $8M | $8M | $7M | $4M | |
| Deferred Tax | · | · | · | · | · | $1M | $-775.0K | $-799.0K | · | |
| Other Non-cash | $141M | $-129M | $-22M | $-6M | $478.0K | $-16M | $27M | $-18M | $36M | |
| Operating Cash Flow | $58M | $184M | $-70M | $-108M | $-108M | $-72M | $-42M | $-50M | $4M | |
| CapEx | $2M | $1M | $609.0K | $795.0K | $1M | $471.0K | $967.0K | $486.0K | $666.0K | |
| Investing Cash Flow | $-49M | $-299M | $-39M | $91M | $-16M | $-91M | $-54M | $2M | $16M | |
| Debt Issued | · | · | · | · | · | · | $10M | · | · | |
| Net Debt Issued | · | · | · | · | · | $-11M | · | · | · | |
| Stock Issued | · | · | $108M | · | $124M | $213M | $34M | $2M | · | |
| Net Stock Activity | · | · | $108M | · | $124M | $213M | $34M | $2M | · | |
| Financing Cash Flow | $23M | $26M | $170M | $19M | $130M | $248M | $46M | $24M | $66M | |
| Net Change in Cash | $31M | $-89M | $61M | $2M | $6M | $84M | $-49M | $-24M | $85M | |
| Taxes Paid | $4M | $2M | · | · | · | · | · | · | · | |
| Free Cash Flow | $56M | $183M | $-71M | $-109M | $-109M | $-73M | $-42M | $-50M | $3M | |
| Levered FCF | · | · | · | · | · | $-74M | $-43M | · | · |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -343.6% | 58.2% | -156.1% | -494.2% | -460.0% | · | · | -136.7% | · | |
| Net Margin | -282.8% | 63.3% | -131.6% | -479.3% | -458.9% | · | · | -125.9% | · | |
| Pretax Margin | -281.0% | 64.3% | -131.6% | -479.3% | -458.9% | · | · | -128.4% | · | |
| EBITDA Margin | -340.9% | 58.4% | -154.5% | -490.4% | -457.0% | · | · | -135.0% | · | |
| ROA | -18.4% | 49.9% | -26.1% | -42.8% | -37.4% | -27.6% | -52.4% | -25.7% | -28.7% | |
| ROE | -20.3% | 45.6% | -24.7% | -55.5% | -39.9% | -29.4% | -88.0% | -32.9% | -35.5% | |
| ROIC | -25.9% | 36.9% | -27.8% | -60.9% | -41.9% | -23.5% | -99.8% | -38.3% | -31.4% |
Liquidez y Solvencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.7 | 12.5 | 16.7 | 7.8 | 7.7 | 7.8 | 4.1 | 5.3 | 3.5 | |
| Quick Ratio | 12.5 | 8.8 | 16.1 | 7.6 | 7.4 | 7.6 | 3.8 | 4.9 | 3.4 | |
| Interest Coverage | · | · | · | · | · | -107.9 | -476.5 | · | · |
Eficiencia 1
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.8 | 0.2 | 0.1 | 0.1 | · | · | 0.2 | · |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -89.4% | 624.1% | 125.7% | -2.8% | -4.4% | · | · | · | · | |
| Revenue CAGR 3Y | 20.1% | 151.3% | 28.0% | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 10.0% | · | · | · | · | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $46M | $434M | $60M | $27M | $27M | $29M | $231.0K | $31M | $20M | |
| Net Income TTM | $-130M | $275M | $-79M | $-127M | $-126M | $-66M | $-77M | $-39M | $-37M | |
| Market Cap | $5.47B | $2.36B | $1.32B | $538M | $1.64B | $882M | $192M | $156M | $439M | |
| P/E | -42.6 | 9.1 | -16.5 | -4.2 | -12.6 | -10.5 | · | · | · | |
| P/S | 118.8 | 5.4 | 22.1 | 20.3 | 59.8 | 30.8 | 830.7 | 5.0 | 21.9 | |
| P/B | 8.9 | 3.5 | 3.9 | 2.5 | 5.5 | 3.2 | 2.4 | 1.4 | 3.6 | |
| P / Tangible Book | 8.9 | 3.5 | 3.9 | 2.5 | 5.5 | 3.2 | · | · | · | |
| P / Cash Flow | 94.8 | 12.8 | -18.8 | -5.0 | -15.2 | -12.2 | -4.6 | -3.1 | 113.3 | |
| P / FCF | 97.5 | 12.9 | -18.7 | -4.9 | -15.0 | -12.1 | -4.5 | -3.1 | 136.8 | |
| Earnings Yield | -2.4% | 11.0% | -6.1% | -23.8% | -7.9% | -9.5% | · | · | · |
Estado de resultados 15
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $213M | $56M | $7M | $5M | $6M | $28M | $171M | $5M | $4M | $255M | $60M | $0 | $0 | $0 | $0 | $0 | |
| R&D Expense | $42M | $47M | $46M | $40M | $37M | $36M | $35M | $36M | $34M | $34M | $29M | $31M | $33M | $27M | $30M | $25M | |
| SG&A Expense | $13M | $13M | $11M | $11M | $11M | $12M | $9M | $10M | $9M | $15M | $8M | $8M | $9M | $9M | $7M | $7M | |
| Operating Expenses | $55M | $60M | $58M | $51M | $48M | $48M | $44M | $46M | $43M | $49M | $37M | $38M | $42M | $36M | $37M | $32M | |
| Operating Income | $159M | $-4M | $-50M | $-46M | $-42M | $-19M | $127M | $-41M | $-39M | $206M | $23M | $-38M | $-42M | $-36M | $-37M | $-32M | |
| Interest Income | $6M | $6M | $7M | $7M | $7M | $8M | $7M | $8M | $7M | $4M | $4M | $4M | $4M | $2M | $2M | $1M | |
| Other Non-op | $-81.0K | $53.0K | $-124.0K | $33.0K | $36.0K | $82.0K | $31.0K | $141.0K | $97.0K | $-19.0K | $44.0K | $-31.0K | $-19.0K | $-195.0K | $71.0K | $-86.0K | |
| Pretax Income | $165M | $2M | $-44M | $-39M | $-35M | $-12M | $134M | $-34M | $-31M | $211M | $27M | $-34M | $-38M | $-34M | · | · | |
| Income Tax | $2M | $-2M | $666.0K | $0 | $172.0K | $0 | $2M | $-420.0K | $-676.0K | $3M | · | $0 | $0 | $0 | · | · | |
| Net Income | $163M | $4M | $-44M | $-39M | $-35M | $-12M | $132M | $-33M | $-31M | $207M | $27M | $-34M | $-38M | $-34M | $-34M | $-31M | |
| EPS (Basic) | $2.47 | $0.06 | $-0.69 | $-0.62 | $-0.55 | $-0.19 | $2.10 | $-0.54 | $-0.50 | $3.41 | $0.54 | $-0.58 | $-0.68 | $-0.67 | $-0.69 | $-0.64 | |
| EPS (Diluted) | $2.29 | $0.05 | $-0.69 | $-0.62 | $-0.55 | $-0.19 | $2.01 | $-0.54 | $-0.50 | $3.26 | $0.54 | $-0.58 | $-0.68 | $-0.67 | $-0.69 | $-0.64 | |
| Shares (Basic) | 65,935,769 | 65,087,847 | -126,673,627 | 63,772,332 | 63,510,537 | 62,963,806 | -122,361,923 | 61,767,934 | 61,305,289 | 60,855,689 | -109,768,732 | 59,182,899 | 56,775,742 | 50,573,650 | -97,867,857 | 49,107,639 | |
| Shares (Diluted) | 71,007,011 | 70,492,618 | -126,673,627 | 63,772,332 | 63,510,537 | 62,963,806 | -121,590,829 | 61,767,934 | 61,305,289 | 63,595,328 | -109,768,732 | 59,182,899 | 56,775,742 | 50,573,650 | -97,867,857 | 49,107,639 | |
| EBITDA | $159M | $-3M | · | $-46M | $-42M | $-19M | · | $-41M | $-39M | $207M | · | $-38M | $-42M | $-36M | · | $-32M |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $420M | $194M | $128M | $114M | $169M | $140M | $97M | $131M | $356M | $173M | $187M | $231M | $235M | $128M | $126M | $153M | |
| Short-term Investments | $362M | $354M | $439M | $462M | $402M | $435M | $322M | $338M | $208M | $150M | · | $90M | $78M | $103M | · | $115M | |
| Prepaid Expense | $8M | $12M | $10M | $10M | $9M | $9M | $8M | $8M | $7M | $5M | · | $4M | $4M | $5M | · | $9M | |
| Other Current Assets | · | · | $10.0K | $191.0K | $92.0K | · | $248.0K | $3M | $1M | $360.0K | · | $65.0K | · | · | · | · | |
| Current Assets | $807M | $613M | $578M | $586M | $603M | $606M | $592M | $477M | $571M | $628M | · | $325M | $317M | $236M | · | $277M | |
| PP&E (Net) | $3M | $4M | $4M | $4M | $4M | $4M | $3M | $2M | $2M | $1M | · | $1M | $1M | $1M | · | $2M | |
| PP&E (Gross) | $13M | $12M | $12M | $12M | $12M | $11M | $10M | $9M | $8M | $8M | · | $7M | $7M | $7M | · | $7M | |
| Accum. Depreciation | $9M | $9M | $8M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | · | $6M | $6M | $5M | · | $5M | |
| Other Non-current Assets | $832.0K | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Total Assets | $886M | $697M | $668M | $702M | $718M | $742M | $745M | $604M | $615M | $629M | · | $330M | $320M | $240M | · | $282M | |
| Accounts Payable | $3M | $8M | $5M | $6M | $3M | $3M | $2M | $3M | $4M | $4M | · | $1M | $5M | $4M | · | $5M | |
| Accrued Liabilities | $22M | $17M | $28M | $23M | $15M | $12M | $24M | $21M | $15M | $16M | · | $25M | $19M | $17M | · | $30M | |
| Current Liabilities | $37M | $35M | $45M | $45M | $36M | $35M | $47M | $45M | $42M | $40M | · | $28M | $26M | $23M | · | $37M | |
| Capital Leases | $7M | $7M | $8M | $9M | $9M | $10M | $10M | $11M | $11M | · | · | · | · | $462.0K | · | $2M | |
| Total Liabilities | $44M | $42M | $53M | $56M | $50M | $53M | $69M | $72M | $73M | $69M | · | $28M | $26M | $24M | · | $39M | |
| Common Stock | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | · | $1.0K | $1.0K | $1.0K | · | · | |
| Retained Earnings | $-304M | $-467M | $-471M | $-426M | $-387M | $-352M | $-341M | $-472M | $-439M | $-408M | · | $-643M | $-609M | $-570M | · | $-503M | |
| AOCI | $-828.0K | $-269.0K | $641.0K | $525.0K | $-15.0K | $85.0K | $-82.0K | $1M | $-249.0K | $-229.0K | · | $-170.0K | $-198.0K | $-122.0K | · | $-480.0K | |
| Stockholders' Equity | $842M | $655M | $615M | $645M | $668M | $689M | $675M | $532M | $541M | $560M | $337M | $302M | $294M | $216M | $216M | $244M | |
| Liabilities + Equity | $886M | $697M | $668M | $702M | $718M | $742M | $745M | $604M | $615M | $629M | · | $330M | $320M | $240M | · | $282M | |
| Shares Outstanding | 64,672,032 | 64,227,057 | 62,577,897 | 62,447,102 | 62,107,572 | 61,928,760 | 61,035,139 | 59,521,903 | 58,762,063 | 58,600,787 | 57,708,613 | 57,647,476 | 57,494,185 | 51,440,503 | 49,339,252 | 49,198,411 |
Flujo de Efectivo 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $397.0K | $407.0K | $376.0K | $361.0K | $304.0K | $239.0K | $118.0K | $231.0K | $241.0K | $236.0K | $248.0K | $244.0K | $237.0K | $248.0K | $256.0K | $270.0K | |
| Stock-based Comp | $14M | $15M | $11M | $11M | $11M | $14M | $9M | $10M | $9M | $9M | $7M | $7M | $8M | $8M | $6M | $6M | |
| Other Non-cash | · | $-68M | · | · | · | $123M | · | · | · | $-244M | · | · | · | $-8M | · | · | |
| Operating Cash Flow | $219M | $-49M | $-37M | $-2M | $-29M | $125M | $-29M | $-28M | $269M | $-27M | $17M | $-27M | $-26M | $-34M | $-32M | $-25M | |
| CapEx | $168.0K | $215.0K | $144.0K | $88.0K | $813.0K | $545.0K | $310.0K | $775.0K | $28.0K | $242.0K | $19.0K | $404.0K | $176.0K | $10.0K | $70.0K | $162.0K | |
| Investing Cash Flow | $-2M | $91M | $49M | $-59M | $55M | $-94M | $-9M | $-209M | $-88M | $6M | $-61M | $-14M | $26M | $10M | $4M | $57M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | $8.0K | $-78.0K | · | · | · | · | |
| Financing Cash Flow | $10M | $23M | $3M | $6M | $3M | $11M | $4M | $12M | $3M | $7M | $527.0K | $35M | $108M | $26M | $553.0K | $680.0K | |
| Net Change in Cash | $226M | $65M | $15M | $-55M | $29M | $42M | $-34M | $-225M | $183M | $-14M | $-44M | $-5M | $108M | $2M | $-27M | $33M | |
| Free Cash Flow | · | $-49M | · | · | · | $125M | · | · | · | $-28M | · | · | · | $-34M | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 74.4% | -6.5% | · | -985.2% | -758.0% | -68.2% | · | -886.7% | -931.0% | 80.9% | · | · | · | · | · | · | |
| Net Margin | 76.3% | 6.7% | · | -834.9% | -627.0% | -41.1% | · | -710.4% | -734.7% | 81.3% | · | · | · | · | · | · | |
| Pretax Margin | 77.3% | 4.0% | · | -834.9% | -623.9% | -41.1% | · | -719.4% | -751.0% | 82.6% | · | · | · | · | · | · | |
| EBITDA Margin | 74.4% | -5.8% | · | -985.2% | -758.0% | -67.3% | · | -886.7% | -931.0% | 81.0% | · | · | · | · | · | · | |
| ROA | 20.3% | 0.53% | · | -6.0% | -5.2% | -1.7% | · | -7.1% | -6.6% | 47.7% | · | -11.1% | -12.2% | -11.5% | · | -9.5% | |
| ROE | 21.6% | 0.56% | · | -6.7% | -5.8% | -1.9% | · | -8.0% | -7.3% | 53.4% | · | -12.5% | -13.7% | -13.0% | · | -10.9% | |
| ROIC | 18.6% | -0.92% | · | -7.2% | -6.3% | -2.8% | · | -7.7% | -7.0% | 36.2% | · | · | · | · | · | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 21.7 | 17.8 | · | 13.0 | 17.0 | 17.3 | · | 10.7 | 13.7 | 15.7 | · | 11.7 | 12.0 | 10.1 | · | 7.5 | |
| Quick Ratio | 21.0 | 15.9 | · | 12.8 | 16.1 | 16.4 | · | 10.5 | 13.6 | 8.1 | · | 11.5 | 11.9 | 9.9 | · | 7.3 |
Eficiencia 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.3 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.6 | · | 0.0 | 0.0 | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $280M | $95M | · | $43M | $43M | $292M | · | $264M | $259M | $255M | · | $0 | $859.0K | $27M | · | $37M | |
| Net Income TTM | $93M | $-82M | · | $-119M | $-110M | $132M | · | $109M | $104M | $101M | · | $-138M | $-144M | $-127M | · | $-127M | |
| Market Cap | $7.93B | $6.77B | · | $4.15B | $3.43B | $2.99B | · | $2.68B | $2.04B | $1.70B | · | $962M | $1.59B | $1.18B | · | $415M | |
| P/E | 104.8 | -80.5 | · | -35.0 | -31.1 | 23.8 | · | 27.4 | 23.1 | 21.8 | · | -6.5 | -9.8 | -8.9 | · | -3.2 | |
| P/S | 28.3 | 71.3 | · | 95.9 | 80.4 | 10.3 | · | 10.2 | 7.9 | 6.6 | · | · | 1848.6 | 44.5 | · | 11.2 | |
| P/B | 9.4 | 10.3 | · | 6.4 | 5.1 | 4.3 | · | 5.0 | 3.8 | 3.0 | · | 3.2 | 5.4 | 5.5 | · | 1.7 | |
| P / Tangible Book | 9.4 | 10.3 | · | 6.4 | 5.1 | 4.3 | · | 5.0 | 3.8 | 3.0 | · | 3.2 | 5.4 | 5.5 | · | 1.7 | |
| P / Cash Flow | · | -138.3 | · | · | · | 23.9 | · | · | · | -61.8 | · | · | · | -34.4 | · | · | |
| P / FCF | · | -137.7 | · | · | · | 24.0 | · | · | · | -61.3 | · | · | · | -34.4 | · | · | |
| Earnings Yield | 0.95% | -1.2% | · | -2.9% | -3.2% | 4.2% | · | 3.6% | 4.3% | 4.6% | · | -15.4% | -10.2% | -11.2% | · | -31.0% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $46M | $434M | $60M | $27M | $27M |
| Margen Operativo % | -343.6% | 58.2% | -156.1% | -494.2% | -460.0% |
| Beneficio neto | $-130M | $275M | $-79M | $-127M | $-126M |
| EPS Diluido | $-2.05 | $4.23 | $-1.39 | $-2.60 | $-2.71 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 12.7 | 12.5 | 16.7 | 7.8 | 7.7 |
| Ratio Rápido | 12.5 | 8.8 | 16.1 | 7.6 | 7.4 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $56M | $183M | $-71M | $-109M | $-109M |
Últimas noticias Noticias recientes que mencionan a esta empresa
Señales de trading Señales recientes de compra/venta con precio de entrada y ratio riesgo/recompensa
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Elige las métricas que te importan — haz clic en el ➕ junto a cualquier fila en Fundamentales Completos arriba.
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Propietarios institucionales (13F) 370 declarantes · $6.0B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 66 (+6 vs trimestre anterior) | 34 (-14 vs trimestre anterior) | 143 (+36 vs trimestre anterior) | 84 (-28 vs trimestre anterior) | +6.9M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $778 248 897 | 6 348 906 | 12,91% | Acciones |
| RTW INVESTMENTS, LP | $620 398 832 | 5 061 175 | 10,29% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $444 879 349 | 3 629 298 | 7,38% | Acciones |
| STATE STREET CORP | $407 156 089 | 3 321 554 | 6,75% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $349 769 037 | 2 853 394 | 5,80% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $349 287 787 | 2 849 468 | 5,79% | Acciones |
| JOHNSON & JOHNSON | $300 220 852 | 2 449 183 | 4,98% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $185 989 291 | 1 516 976 | 3,08% | Acciones |
| Woodline Partners LP | $173 349 326 | 1 414 173 | 2,87% | Acciones |
| BANK OF AMERICA CORP /DE/ | $140 547 654 | 1 146 579 | 2,33% | Acciones |
| PERCEPTIVE ADVISORS LLC | $120 358 728 | 981 879 | 2,00% | Acciones |
| ADAR1 Capital Management, LLC | $117 782 587 | 960 863 | 1,95% | Acciones |
| JENNISON ASSOCIATES LLC | $112 878 407 | 920 855 | 1,87% | Acciones |
| Alyeska Investment Group, L.P. | $109 010 149 | 889 298 | 1,81% | Acciones |
| Hood River Capital Management LLC | $108 206 024 | 882 738 | 1,79% | Acciones |
| Driehaus Capital Management LLC | $89 612 477 | 731 053 | 1,49% | Acciones |
| Clearbridge Investments, LLC | $88 911 554 | 725 335 | 1,47% | Acciones |
| FMR LLC | $82 247 135 | 670 967 | 1,36% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $73 376 587 | 598 600 | 1,22% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $71 559 017 | 583 774 | 1,19% | Acciones |
| Pictet Asset Management Holding SA | $69 624 214 | 567 990 | 1,15% | Acciones |
| GOLDMAN SACHS GROUP INC | $69 261 132 | 565 028 | 1,15% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $53 659 027 | 437 747 | 0,89% | Acciones |
| PRINCIPAL FINANCIAL GROUP INC | $46 648 554 | 380 556 | 0,77% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $36 954 438 | 301 472 | 0,61% | Acciones |
| 683 Capital Management, LLC | $35 548 200 | 290 000 | 0,59% | Acciones |
| Stephens Investment Management Group LLC | $34 546 967 | 281 832 | 0,57% | Acciones |
| Eagle Health Investments LP | $30 439 311 | 248 322 | 0,50% | Acciones |
| NEUBERGER BERMAN GROUP LLC | $30 311 828 | 247 282 | 0,50% | Acciones |
| NEXTBio Capital Management LP | $26 885 839 | 219 333 | 0,45% | Acciones |
| SEGALL BRYANT & HAMILL, LLC | $26 320 868 | 214 724 | 0,44% | Acciones |
| SEB Asset Management AB | $25 737 215 | 209 963 | 0,43% | Acciones |
| Public Sector Pension Investment Board | $25 458 395 | 207 688 | 0,42% | Acciones |
| Bank of New York Mellon Corp | $22 273 031 | 181 702 | 0,37% | Acciones |
| Affinity Asset Advisors, LLC | $21 099 083 | 172 125 | 0,35% | Acciones |
| Fisher Asset Management, LLC | $20 902 831 | 170 524 | 0,35% | Acciones |
| Boxer Capital Management, LLC | $20 838 600 | 170 000 | 0,35% | Acciones |
| Caption Management, LLC | $19 833 444 | 161 800 | 0,33% | Opción de venta |
| NAN FUNG TRINITY (HK) LTD | $19 694 929 | 160 670 | 0,33% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $18 592 199 | 151 674 | 0,31% | Acciones |
| Caption Management, LLC | $18 387 000 | 150 000 | 0,30% | Opción de compra |
| ORBIMED ADVISORS LLC | $18 387 000 | 150 000 | 0,30% | Opción de compra |
| AMERIPRISE FINANCIAL INC | $17 395 696 | 141 913 | 0,29% | Acciones |
| RHUMBLINE ADVISERS | $17 317 951 | 141 279 | 0,29% | Acciones |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $17 294 000 | 141 081 | 0,29% | Acciones |
| TD Asset Management Inc | $16 542 171 | 134 950 | 0,27% | Acciones |
| KENNEDY CAPITAL MANAGEMENT LLC | $16 428 049 | 134 019 | 0,27% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $13 306 672 | 108 555 | 0,22% | Acciones |
| Catalio Capital Management, LP | $13 091 421 | 106 799 | 0,22% | Acciones |
| Swiss National Bank | $12 552 192 | 102 400 | 0,21% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $12 503 406 | 102 002 | 0,21% | Acciones |
| Opaleye Management Inc. | $12 258 000 | 100 000 | 0,20% | Acciones |
| ASSETMARK, INC | $12 097 052 | 98 687 | 0,20% | Acciones |
| JANUS HENDERSON GROUP PLC | $12 077 934 | 114 575 | 0,20% | Acciones |
| Legal & General Group Plc | $11 363 044 | 92 699 | 0,19% | Acciones |
| ALGERT GLOBAL LLC | $10 750 021 | 87 698 | 0,18% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $10 282 379 | 83 883 | 0,17% | Acciones |
| VOYA INVESTMENT MANAGEMENT LLC | $10 246 953 | 83 594 | 0,17% | Acciones |
| AXIOM INVESTORS LLC /DE | $10 012 702 | 81 683 | 0,17% | Acciones |
| PRUDENTIAL FINANCIAL INC | $9 693 626 | 79 080 | 0,16% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $8 385 940 | 79 563 | 0,14% | Acciones |
| Nuveen, LLC | $8 236 886 | 67 196 | 0,14% | Acciones |
| BlackRock, Inc. | $8 091 628 | 66 011 | 0,13% | Acciones |
| Knott David M Jr | $7 722 540 | 63 000 | 0,13% | Acciones |
| Moody Aldrich Partners LLC | $7 305 891 | 59 601 | 0,12% | Acciones |
| Eversept Partners, LP | $7 171 420 | 58 504 | 0,12% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6 994 660 | 57 062 | 0,12% | Acciones |
| Bellevue Group AG | $6 825 500 | 55 682 | 0,11% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6 790 932 | 55 400 | 0,11% | Opción de venta |
| FIRST TRUST ADVISORS LP | $6 725 351 | 54 865 | 0,11% | Acciones |
| KVP Capital Advisors, LP | $6 496 740 | 53 000 | 0,11% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $6 329 909 | 51 639 | 0,10% | Acciones |
| CASTLEARK MANAGEMENT LLC | $6 198 871 | 50 570 | 0,10% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $6 184 556 | 58 677 | 0,10% | Acciones |
| Granahan Investment Management, LLC | $6 105 587 | 49 809 | 0,10% | Acciones |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | $5 993 427 | 48 894 | 0,10% | Acciones |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $5 597 983 | 45 668 | 0,09% | Acciones |
| Seven Fleet Capital Management LP | $5 565 132 | 45 400 | 0,09% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5 565 132 | 45 400 | 0,09% | Opción de compra |
| Caption Management, LLC | $5 516 100 | 45 000 | 0,09% | Acciones |
| EFG Asset Management (North America) Corp. | $5 492 601 | 82 639 | 0,09% | Acciones |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $5 458 365 | 44 529 | 0,09% | Acciones |
| GREAT LAKES ADVISORS, LLC | $5 369 004 | 43 800 | 0,09% | Acciones |
| ORBIMED ADVISORS LLC | $5 160 618 | 42 100 | 0,09% | Acciones |
| Elmind Capital, LP | $4 658 040 | 38 000 | 0,08% | Acciones |
| LMR Partners LLP | $4 658 040 | 38 000 | 0,08% | Acciones |
| Atika Capital Management LLC | $4 444 260 | 36 256 | 0,07% | Acciones |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $4 443 770 | 36 252 | 0,07% | Acciones |
| MetLife Investment Management, LLC | $4 387 383 | 35 792 | 0,07% | Acciones |
| Birchview Capital, LP | $4 292 506 | 35 018 | 0,07% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $4 063 772 | 33 152 | 0,07% | Acciones |
| CITADEL ADVISORS LLC | $3 971 592 | 32 400 | 0,07% | Opción de compra |
| Aquilo Capital Management, LLC | $3 950 625 | 81 692 | 0,07% | Acciones |
| MORGAN STANLEY | $3 857 347 | 31 468 | 0,06% | Acciones |
| Illinois Municipal Retirement Fund | $3 580 684 | 29 211 | 0,06% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $3 574 555 | 29 161 | 0,06% | Acciones |
| Vanguard Global Advisers, LLC | $3 488 995 | 28 463 | 0,06% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $3 474 530 | 28 345 | 0,06% | Acciones |
| DEUTSCHE BANK AG\ | $3 463 620 | 28 256 | 0,06% | Acciones |
| Schonfeld Strategic Advisors LLC | $3 441 064 | 28 072 | 0,06% | Acciones |
Informantes de la empresa 20 insiders · 9 directivos · 10 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Asif Ali | Chief Financial Officer | 20 de abril de 2026 S | 59 003 | 0 | 5 | $-7 315 451 |
| Donald A. Kalkofen | Chief Financial Officer | 15 de febrero de 2022 A | 18 521 | 0 | 0 | $0 |
| Thomas P. O'Neil | Chief Financial Officer | 15 de agosto de 2018 A | 30 560 | 0 | 0 | $0 |
| Arturo Molina MD | Chief Medical Officer | 26 de marzo de 2026 M | 84 115 | 0 | 6 | $-4 491 766 |
| Suneel Gupta | Chief Development Officer | 26 de noviembre de 2024 M | 267 433 | 0 | 0 | $0 |
| David Y Liu | Chief R&D Strategy Officer | 16 de noviembre de 2022 M | 167 590 | 0 | 0 | $0 |
| Samuel R Saks | Chief Medical Officer | 26 de febrero de 2021 A | 14 000 | 0 | 0 | $0 |
| Richard S Shame | Chief Medical Officer | 28 de febrero de 2019 A | 32 021 | 0 | 0 | $0 |
| William A Hodder | Sr. VP - Corporate Development | 11 de octubre de 2016 A | — | 0 | 0 | $0 |
| William D. Waddill | Consejero | 23 de junio de 2026 M | 7 825 | 0 | 8 | $-6 074 420 |
| Bryan Giraudo | Consejero | 7 de mayo de 2026 M | 12 695 | 0 | 4 | $-5 918 880 |
| Harold E Selick | Consejero | 26 de marzo de 2026 M | 60 845 | 0 | 1 | $-2 520 000 |
| Lewis T Williams | Consejero | 17 de febrero de 2026 M | 7 825 | 0 | 1 | $-1 483 560 |
| Sarah A O'Dowd | Consejero | 2 de enero de 2026 A | 7 825 | 0 | 0 | $0 |
| Daniel N Swisher JR | Consejero | 26 de octubre de 2023 A | — | 0 | 0 | $0 |
| Sarah B. Noonberg | Consejero | 16 de enero de 2023 A | 0 | 0 | 0 | $0 |
| Chaitan Khosla PHD | Consejero | 11 de agosto de 2020 M | 0 | 0 | 0 | $0 |
| Armen Shanafelt | Consejero | 29 de mayo de 2018 A | 2 099 482 | 0 | 0 | $0 |
| Julie Papanek | Consejero | 25 de mayo de 2017 A | 2 453 255 | 0 | 0 | $0 |
| PATEL DINESH V PH D | — | 11 de agosto de 2026 M | 523 478 | 0 | 11 | $-42 337 688 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 1 tenencia
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Lilly Ventures Fund I, LLC, LV Management Group, LLC, S. Edward Torres, Steven E. Hall, Ph.D., Armen B. Shanafelt, Ph.D. ×2 presentaciones | 8 de junio de 2020 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 77 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| NBDS · Neuberger Berman ETF Trust | 2,97% | 10 761 NS | 31 de mayo de 2026 | N-PORT |
| CAFG · Pacer Funds Trust | 2,15% | 4 916 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,96% | 50 321 NS | 30 de abril de 2026 | N-PORT |
| VAMO · Cambria ETF Trust | 0,82% | 6 865 NS | 30 de abril de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,77% | 2 894 NS | 30 de abril de 2026 | N-PORT |
| FDMO · FIDELITY COVINGTON TRUST | 0,72% | 61 466 NS | 30 de abril de 2026 | N-PORT |
| PSC · Principal Exchange-Traded Funds | 0,47% | 88 659 NS | 30 de junio de 2026 | N-PORT |
| ESSC · Strategy Shares | 0,41% | 1 068 NS | 30 de abril de 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,41% | 2 139 NS | 31 de mayo de 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,37% | 19 517 NS | 30 de abril de 2026 | N-PORT |
| AFSM · First Trust Exchange-Traded Fund VI… | 0,33% | 3 261 NS | 31 de mayo de 2026 | N-PORT |
| BIB · ProShares Trust | 0,32% | 2 361 NS | 31 de mayo de 2026 | N-PORT |
| JPSE · J.P. Morgan Exchange-Traded Fund Tr… | 0,29% | 17 406 NS | 30 de abril de 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,27% | 20 237 NS | 30 de abril de 2026 | N-PORT |
| BKSE · BNY Mellon ETF Trust | 0,26% | 2 151 NS | 30 de abril de 2026 | N-PORT |
| SAA · ProShares Trust | 0,26% | 705 NS | 31 de mayo de 2026 | N-PORT |
| ROSC · Lattice Strategies Trust | 0,17% | 917 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,15% | 2 739 NS | 31 de mayo de 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,13% | 17 224 NS | 30 de abril de 2026 | N-PORT |
| ESUM · Strategy Shares | 0,13% | 1 964 NS | 30 de abril de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,12% | 282 329 NS | 31 de mayo de 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,11% | 5 370 NS | 30 de abril de 2026 | N-PORT |
| UWM · ProShares Trust | 0,09% | 2 143 NS | 31 de mayo de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,08% | 8 339 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,08% | 23 132 NS | 30 de abril de 2026 | N-PORT |
| URTY · ProShares Trust | 0,06% | 2 169 NS | 31 de mayo de 2026 | N-PORT |
| AFMC · First Trust Exchange-Traded Fund VI… | 0,06% | 937 NS | 31 de mayo de 2026 | N-PORT |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,05% | 51 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,04% | 62 681 NS | 30 de abril de 2026 | N-PORT |
| SMDX · Tidal Trust III | 0,04% | 474 NS | 30 de abril de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,03% | 2 278 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,02% | 54 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 16 137 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 3 216 NS | 30 de abril de 2026 | N-PORT |
| TILT · FlexShares Trust | 0,01% | 1 694 NS | 30 de abril de 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,01% | 34 764 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,01% | 8 569 NS | 30 de abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 9 634 NS | 30 de abril de 2026 | N-PORT |
| AVLC · AMERICAN CENTURY ETF TRUST | 0,00% | 388 NS | 31 de mayo de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 5 700 NS | 30 de abril de 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 428 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 de julio de 2026 | Diario |
| VB · VANGUARD INDEX FUNDS | — | — | 15 de julio de 2026 | Diario |
| VBK · VANGUARD INDEX FUNDS | — | — | 15 de julio de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 de julio de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | — | — | 30 de julio de 2026 | Diario |
| VT · VANGUARD INTERNATIONAL EQUITY INDEX… | — | — | 15 de julio de 2026 | Diario |
| VIOO · VANGUARD ADMIRAL FUNDS | — | — | 15 de julio de 2026 | Diario |
| VIOG · VANGUARD ADMIRAL FUNDS | — | — | 30 de julio de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 15 de julio de 2026 | Diario |