QURE uniQure N.V. - Ordinary Shares
$47,19
Precio · Ago 19, 2026
Fundamentales a fecha de Jul 29, 2026
Rango 52S
$9–$72
61% of range
Calificación del Analista
BUY
20 analysts
Precio Objetivo
$70
+48% upside
P/E (TTM)
-13.8
ROE
-204.2%
Margen de Beneficio Neto
-1236.0%
QURE Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$47.19
Capitalización Bursátil
$2.97B
P/E (TTM)
-13.8
BPA (TTM)
$-3.46
Ingresos (TTM)
$16M
Rendimiento div.
—
ROE
-204.2%
Deuda/Capital
0.2
Rango 52S
$9 – $72
QURE Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$16M
2016-12-31
→
2025-12-31
BPA
$-3.46
2019-12-31
→
2025-12-31
Flujo de caja libre
$-178M
2016-12-31
→
2025-12-31
Márgenes
-1236.0%
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
QURE
Mediana de Pares
P/E (TTM)
-13.8
—
P/S (TTM) (P/V (TTM))
184.8
92.4
P/B (P/C)
15.0
5.8
EV / EBITDA
-15.9
—
Price / FCF (Precio / FCF)
-16.7
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
QURE
Mediana de Pares
Operating Margin (Margen Operativo)
-1151.4%
—
Net Profit Margin (Margen de Beneficio Neto)
-1236.0%
-905.7%
ROA
-28.8%
-27.1%
ROE
-204.2%
-58.4%
ROIC
-76.7%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
QURE
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
0.2
28.9
Current Ratio (Ratio corriente)
10.4
7.9
Quick Ratio (Ratio Rápido)
1.3
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
QURE
Mediana de Pares
Revenue YoY (Ingresos interanuales)
-40.6%
—
Revenue CAGR 3Y (Ingresos CAGR 3A)
-46.7%
—
Revenue CAGR 5Y (Ingresos CAGR 5A)
-15.6%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
QURE
Mediana de Pares
QURE Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
20 analistas
- Compra fuerte 7 35,0%
- Compra 11 55,0%
- Mantener 2 10,0%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
11 analistas · 2026-08-15
Mediana
$69.15
Ahora
$47.19
Mín
$46.78
Máx
$96.61
Objetivo mediano
$69.15
+46,5%
Objetivo medio
$69.78
+47,9%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
-0.01%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-1.22 | $-0.84 | -0.38% |
| 31 de marzo de 2026 | $-0.85 | $-0.89 | 0.04% |
| 31 de diciembre de 2025 | $-0.64 | $-0.97 | 0.33% |
| 30 de septiembre de 2025 | $-1.38 | $-0.92 | -0.46% |
| 30 de junio de 2025 | $-0.69 | $-0.91 | 0.22% |
| 31 de marzo de 2025 | $-0.82 | $-1.03 | 0.21% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| QURE | $1.49B | -6.9 | -40.6% | -1236.0% | -204.2% | — |
| NAMS | — | — | — | — | — | — |
| PRQR | — | — | — | — | — | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 17
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $16M | $27M | $16M | $106M | $524M | $38M | $7M | $11M | $13M | $25M | $11M | |
| Cost of Revenue | $2M | $1M | $65.0K | $1M | $25M | $3M | $2M | $1M | $817.0K | $1M | · | |
| R&D Expense | $141M | $144M | $215M | $198M | $144M | $122M | $95M | $75M | $72M | $73M | $59M | |
| SG&A Expense | $65M | $53M | $75M | $55M | $56M | $43M | $34M | $25M | $25M | $26M | $23M | |
| Operating Expenses | $208M | $215M | $303M | $256M | $225M | $165M | $128M | $100M | $97M | $99M | $83M | |
| Operating Income | $-185M | $-184M | $-283M | $-143M | $311M | $-125M | $-121M | $-88M | $-71M | $-72M | $-71M | |
| Interest Expense | · | · | $42M | $12M | $7M | $4M | $4M | $2M | $2M | $2M | $3M | |
| Interest Income | $17M | $21M | $20M | $609.0K | $162.0K | $938.0K | $4M | $3M | $117.0K | $70.0K | $121.0K | |
| Other Non-op | $11M | · | · | $3M | $-160.0K | $483.0K | $-3M | $208.0K | $-2M | $785.0K | $-7M | |
| Pretax Income | $-193M | $-237M | $-307M | $-128M | $333M | $-141M | $-124M | $-83M | $-79M | $-72M | $-83M | |
| Income Tax | $6M | $2M | $2M | $-1M | $3M | $-16M | · | $231.0K | $-199.0K | $1M | $-1M | |
| Net Income | $-199M | $-240M | $-308M | $-127M | $330M | $-125M | $-124M | $-83M | $-79M | $-73M | $-82M | |
| EPS (Basic) | $-3.46 | $-4.92 | $-6.47 | $-2.71 | $7.17 | $-2.81 | $-3.11 | · | · | · | · | |
| EPS (Diluted) | $-3.46 | $-4.92 | $-6.47 | $-2.71 | $7.04 | $-2.81 | $-3.11 | · | · | · | · | |
| Shares (Basic) | 57,502,068 | 48,649,129 | 47,670,986 | 46,735,045 | 45,986,467 | 44,466,365 | 39,999,450 | · | · | · | · | |
| Shares (Diluted) | 57,502,068 | 48,649,129 | 47,670,986 | 46,735,045 | 46,840,972 | 44,466,365 | 39,999,450 | · | · | · | · | |
| EBITDA | $-185M | $-184M | $-283M | $-143M | $311M | $-125M | $-121M | · | $-71M | $-72M | · |
Balance general 29
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $80M | $159M | $241M | $228M | $556M | $245M | $378M | $235M | $159M | $132M | $222M | |
| Receivables | $6M | · | · | · | · | $7M | · | · | · | $4M | · | |
| Inventory | · | · | $12M | $7M | · | · | · | · | · | · | $474.0K | |
| Prepaid Expense | $21M | $9M | $15M | $12M | $11M | $4M | $5M | $1M | $1M | $996.0K | $690.0K | |
| Other Current Assets | · | · | · | · | · | $3M | $748.0K | $329.0K | $687.0K | $1M | $1M | |
| Current Assets | $656M | $390M | $652M | $477M | $628M | $259M | $384M | $237M | $163M | $144M | $228M | |
| PP&E (Net) | $14M | $20M | $47M | $51M | $44M | $32M | $29M | $29M | $34M | $36M | $26M | |
| PP&E (Gross) | $58M | $52M | $102M | $95M | $80M | $68M | $57M | $52M | $51M | $48M | $37M | |
| Accum. Depreciation | $44M | $32M | $56M | $44M | $37M | $35M | $29M | $23M | $17M | $12M | $11M | |
| Goodwill | $25M | $22M | $26M | $26M | $28M | $542.0K | $496.0K | $506.0K | $530.0K | $465.0K | $481.0K | |
| Intangibles | $73M | $71M | $60M | $59M | $63M | $3M | $5M | $5M | $10M | $8M | $7M | |
| Other Non-current Assets | $6M | $1M | $3M | $6M | $6M | $3M | · | · | $2M | $2M | $1M | |
| Total Assets | $825M | $557M | $832M | $705M | $809M | $340M | $449M | $274M | $210M | $190M | $263M | |
| Accounts Payable | $5M | $7M | $7M | $11M | $3M | $4M | $6M | $4M | $3M | $6M | $4M | |
| Accrued Liabilities | $41M | $29M | $31M | $31M | $28M | $18M | $12M | $8M | · | · | · | |
| Current Liabilities | $63M | $40M | $74M | $76M | $37M | $27M | $32M | $20M | $19M | $23M | $27M | |
| Capital Leases | $10M | $11M | $28M | $32M | $29M | $30M | $31M | · | · | · | · | |
| Deferred Tax | $8M | $7M | $8M | $8M | $13M | · | · | · | · | · | · | |
| Other Non-current Liabilities | $4M | $8M | $4M | $935.0K | $4M | $3M | $534.0K | $435.0K | $614.0K | $51.0K | $578.0K | |
| Total Liabilities | $626M | $563M | $624M | $229M | $213M | $96M | $126M | $94M | $120M | $127M | $135M | |
| Long-term Debt | $72M | $66M | $148M | $144M | $136M | $42M | $47M | $48M | $24M | $20M | $20M | |
| Total Debt | $50M | $51M | $102M | $103M | $101M | $36M | $36M | · | $21M | $20M | · | |
| Common Stock | $4M | $3M | $3M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | $2M | |
| Paid-in Capital | $1.58B | $1.17B | $1.15B | $1.11B | $1.08B | $1.02B | $987M | $720M | $567M | $465M | $456M | |
| Retained Earnings | $-1.33B | $-1.13B | $-890M | $-582M | $-455M | $-785M | $-660M | $-536M | $-475M | $-396M | $-323M | |
| AOCI | $-58M | $-53M | $-54M | $-58M | $-29M | $-10M | $-7M | $-7M | $-4M | $-7M | $-7M | |
| Stockholders' Equity | $199M | $-7M | $208M | $476M | $596M | $244M | $323M | $180M | $89M | $64M | $128M | |
| Liabilities + Equity | $825M | $557M | $832M | $705M | $809M | $340M | $449M | $274M | $210M | $190M | $263M | |
| Shares Outstanding | 62,336,717 | 48,988,087 | 47,833,830 | 46,968,032 | 46,298,635 | 44,777,799 | 43,711,954 | 37,351,653 | 31,339,040 | 25,257,420 | 24,327,944 |
Flujo de Efectivo 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $15M | $13M | $12M | $9M | $7M | $11M | $7M | $12M | $8M | · | · | |
| Stock-based Comp | $18M | $22M | $35M | $34M | $26M | $22M | $18M | $11M | $10M | $6M | $12M | |
| Deferred Tax | $2M | $2M | $2M | $-1M | $3M | $-16M | · | $209.0K | $-209.0K | $1M | $-1M | |
| Restructuring | · | · | $3M | · | · | · | · | · | · | · | · | |
| Operating Cash Flow | $-178M | $-183M | $-146M | $-145M | $288M | $-135M | $-99M | $-76M | $-64M | $-72M | $7M | |
| CapEx | $439.0K | $3M | $7M | $18M | $17M | $7M | $6M | $2M | $4M | $15M | $8M | |
| Investing Cash Flow | $-322M | $163M | $-206M | $-183M | $-67M | $-9M | $-7M | $-4M | $-6M | $-17M | $-8M | |
| Debt Issued | · | · | · | · | $64M | · | · | $15M | · | · | · | |
| Net Debt Issued | · | $-53M | · | · | $64M | · | · | · | · | · | · | |
| Stock Issued | · | · | · | · | $31M | $7M | $6M | $5M | $4M | $3M | $3M | |
| Net Stock Activity | · | · | · | · | $3M | $7M | $6M | · | $4M | $3M | · | |
| Financing Cash Flow | $415M | $-59M | $363M | $1M | $95M | $7M | $249M | $158M | $90M | $2M | $161M | |
| Net Change in Cash | $-79M | $-84M | $13M | $-328M | $312M | $-133M | $143M | $75M | $28M | $-89M | $157M | |
| Taxes Paid | $8M | $21.0K | $12.0K | · | · | · | · | · | · | · | · | |
| Free Cash Flow | $-178M | $-186M | $-153M | $-163M | $271M | $-142M | $-104M | · | $-69M | $-87M | · | |
| Levered FCF | · | · | $-195M | $-174M | $263M | $-145M | · | · | $-71M | $-90M | · |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1151.4% | -679.6% | -1785.5% | -134.4% | 59.3% | -334.3% | -1663.8% | · | -544.3% | -286.7% | · | |
| Net Margin | -1236.0% | -883.4% | -1947.1% | -119.1% | 62.9% | -333.3% | -1705.8% | · | -604.7% | · | · | |
| Pretax Margin | -1201.0% | -874.4% | -1935.0% | -120.4% | 63.5% | -377.0% | -1705.8% | · | -606.2% | -287.8% | · | |
| EBITDA Margin | -1151.4% | -679.6% | -1785.5% | -134.4% | 59.3% | -334.3% | -1663.8% | · | -544.3% | -286.7% | · | |
| ROA | -28.8% | -34.5% | -40.2% | -16.8% | 57.3% | -31.7% | -34.4% | · | -39.6% | · | · | |
| ROE | -204.2% | -976.4% | -129.5% | -28.3% | 55.6% | -53.0% | -36.9% | · | -103.6% | · | · | |
| ROIC | -76.7% | -417.7% | -92.0% | -24.4% | 44.1% | -39.7% | · | · | -64.6% | -87.2% | · |
Liquidez y Solvencia 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 10.4 | 9.7 | 8.8 | 6.3 | 17.1 | 9.5 | 12.1 | · | 8.5 | 6.3 | · | |
| Quick Ratio | 1.3 | 4.0 | 3.3 | 3.0 | 15.1 | 9.2 | 11.9 | · | 8.3 | 6.0 | · | |
| Debt / Equity | 0.2 | -7.6 | 0.5 | 0.2 | 0.2 | 0.1 | 0.1 | · | 0.2 | 0.3 | · | |
| LT Debt / Equity | 0.2 | -7.6 | 0.5 | 0.2 | 0.2 | 0.1 | 0.1 | · | 0.2 | 0.3 | · | |
| Interest Coverage | · | · | -6.8 | -12.2 | 41.6 | -32.8 | -31.8 | · | -32.0 | -33.1 | · |
Eficiencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | 0.1 | 0.9 | 0.1 | 0.0 | · | 0.1 | 0.1 | · | |
| Inventory Turnover | · | · | 0.0 | 0.3 | · | · | · | · | · | · | · | |
| Receivables Turnover | · | · | · | · | · | 7.3 | · | · | · | 13.6 | · |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -40.6% | 71.2% | -85.1% | -79.7% | 1296.8% | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -46.7% | -62.7% | -25.0% | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | -15.6% | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $16M | $27M | $16M | $106M | $524M | $38M | $7M | $11M | $13M | $25M | · | |
| Net Income TTM | $-199M | $-240M | $-308M | $-127M | $330M | $-125M | $-124M | $-83M | $-79M | $-73M | · | |
| Market Cap | $1.49B | $865M | $324M | $1.06B | $960M | $1.62B | $3.13B | · | $614M | $141M | · | |
| Enterprise Value | $1.46B | $758M | $184M | $940M | $505M | $1.41B | $2.79B | · | $475M | $29M | · | |
| P/E | -6.9 | -3.6 | -1.0 | -8.4 | 2.9 | -12.9 | -23.0 | · | · | · | · | |
| P/S | 92.7 | 31.9 | 20.4 | 10.0 | 1.8 | 43.1 | 430.2 | · | 46.8 | 5.6 | · | |
| P/B | 7.5 | -128.1 | 1.6 | 2.2 | 1.6 | 6.6 | 9.7 | · | 6.9 | 2.2 | · | |
| P / Tangible Book | 14.8 | · | 2.7 | 2.7 | 1.9 | 6.7 | · | · | · | · | · | |
| P / Cash Flow | -8.4 | -4.7 | -2.2 | -7.3 | 3.3 | -12.0 | -31.7 | · | -9.6 | -2.0 | · | |
| P / FCF | -8.4 | -4.6 | -2.1 | -6.5 | 3.5 | -11.4 | -30.0 | · | -8.9 | -1.6 | · | |
| EV / EBITDA | -7.9 | -4.1 | -0.7 | -6.6 | 1.6 | -11.2 | -23.0 | · | -6.7 | -0.4 | · | |
| EV / FCF | -8.2 | -4.1 | -1.2 | -5.8 | 1.9 | -9.9 | -26.7 | · | -6.9 | -0.3 | · | |
| EV / Revenue | 90.8 | 27.9 | 11.6 | 8.8 | 1.0 | 37.5 | 383.3 | · | 36.3 | 1.2 | · | |
| Earnings Yield | -14.5% | -27.9% | -95.6% | -11.9% | 33.9% | -7.8% | -4.3% | · | · | · | · |
Estado de resultados 17
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $6M | $4M | $6M | $4M | $5M | $2M | $5M | $2M | $11M | $8M | $7M | $1M | $2M | $5M | $103M | $1M | |
| Cost of Revenue | $350.0K | $219.0K | $435.0K | $398.0K | $656.0K | $197.0K | $619.0K | $264.0K | $234.0K | $150.0K | · | · | · | · | · | · | |
| R&D Expense | $34M | $29M | $35M | $34M | $35M | $36M | $39M | $31M | $34M | $41M | $43M | $65M | $46M | $61M | $58M | $48M | |
| SG&A Expense | $17M | $20M | $22M | $19M | $14M | $11M | $11M | $12M | $16M | $14M | $17M | $18M | $21M | $18M | $18M | $13M | |
| Operating Expenses | $52M | $49M | $57M | $54M | $50M | $47M | $51M | $43M | $57M | $64M | $69M | $84M | $69M | $81M | $78M | $62M | |
| Operating Income | $-52M | $-46M | $-51M | $-51M | $-44M | $-39M | $-46M | $-40M | $-44M | $-54M | $-62M | $-82M | $-65M | $-74M | $26M | $-60M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | $16M | · | $15M | $7M | $4M | · | $3M | |
| Interest Income | $5M | $5M | $6M | $4M | $4M | $4M | $4M | $5M | $6M | $7M | $7M | $7M | $3M | $2M | $493.0K | $39.0K | |
| Other Non-op | $-16M | $4M | $18M | $-7M | · | · | · | · | · | · | · | · | · | · | $2M | $0 | |
| Pretax Income | $-79M | $-53M | $-41M | $-72M | $-37M | $-43M | $-72M | $-44M | $-55M | $-65M | $-70M | $-90M | $-68M | $-78M | $7M | $-48M | |
| Income Tax | $2M | $488.0K | $-4M | $9M | $425.0K | $496.0K | $856.0K | $-31.0K | $948.0K | $656.0K | $3M | $-69.0K | $163.0K | $-1M | $-207.0K | $-329.0K | |
| Net Income | $-81M | $-54M | $-37M | $-81M | $-38M | $-44M | $-73M | $-44M | $-56M | $-66M | $-73M | $-90M | $-68M | $-77M | $7M | $-48M | |
| EPS (Basic) | $-1.22 | $-0.85 | $-0.57 | $-1.38 | $-0.69 | $-0.82 | $-1.49 | $-0.91 | $-1.16 | $-1.36 | $-1.52 | $-1.88 | $-1.44 | $-1.63 | $0.15 | $-1.02 | |
| EPS (Diluted) | $-1.22 | $-0.85 | $-0.57 | $-1.38 | $-0.69 | $-0.82 | $-1.49 | $-0.91 | $-1.16 | $-1.36 | $-1.52 | $-1.88 | $-1.44 | $-1.63 | $0.15 | $-1.02 | |
| Shares (Basic) | 66,243,879 | 62,742,847 | -108,932,894 | 58,516,415 | 54,807,967 | 53,110,580 | -97,076,354 | 48,718,533 | 48,622,440 | 48,384,510 | -95,184,970 | 47,770,101 | 47,649,520 | 47,436,335 | -93,305,053 | 46,772,430 | |
| Shares (Diluted) | 66,243,879 | 62,742,847 | -108,932,894 | 58,516,415 | 54,807,967 | 53,110,580 | -97,076,354 | 48,718,533 | 48,622,440 | 48,384,510 | -95,184,970 | 47,770,101 | 47,649,520 | 47,436,335 | -93,305,053 | 46,772,430 | |
| EBITDA | $-52M | $-46M | · | $-51M | $-44M | $-39M | · | $-40M | $-44M | $-54M | · | $-82M | $-65M | $-74M | · | $-60M |
Balance general 28
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $413M | $140M | $80M | $597M | $254M | $217M | $159M | $252M | $288M | $243M | $241M | $229M | $514M | $154M | $228M | $440M | |
| Receivables | $6M | $4M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Inventory | · | · | · | · | · | · | · | · | · | $8M | · | $16M | $10M | $7M | · | $4M | |
| Prepaid Expense | $10M | $17M | $21M | $10M | $19M | $13M | $9M | $19M | $18M | $19M | · | $15M | $12M | $13M | · | $14M | |
| Current Assets | $834M | $616M | $656M | $716M | $409M | $435M | $390M | $464M | $592M | $596M | · | $694M | $757M | $443M | · | $465M | |
| PP&E (Net) | $11M | $12M | $14M | $15M | $17M | $18M | $20M | $26M | $26M | $45M | · | $46M | $49M | $50M | · | $48M | |
| PP&E (Gross) | · | · | $58M | · | · | · | $52M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $44M | $44M | $41M | $36M | $32M | $31M | $28M | $58M | · | $52M | $49M | $47M | · | $40M | |
| Goodwill | $25M | $25M | $25M | $25M | $25M | $23M | $22M | $24M | $23M | $26M | · | $25M | $26M | $26M | · | $23M | |
| Intangibles | $62M | $70M | $73M | $74M | $76M | $72M | $71M | $77M | $59M | $59M | · | $58M | $60M | $60M | · | $54M | |
| Other Non-current Assets | $5M | $6M | $6M | $5M | $5M | $5M | $1M | $1M | $5M | $5M | · | $6M | $6M | $6M | · | $6M | |
| Total Assets | $985M | $779M | $825M | $888M | $585M | $605M | $557M | $646M | $731M | $770M | · | $872M | $943M | $631M | · | $638M | |
| Accounts Payable | $5M | $4M | $5M | $6M | $6M | $5M | $7M | $5M | $4M | $5M | · | $6M | $9M | $9M | · | $8M | |
| Accrued Liabilities | $51M | $43M | $41M | $52M | $31M | $27M | $29M | $32M | $26M | $23M | · | $28M | $24M | $23M | · | $26M | |
| Current Liabilities | $83M | $59M | $63M | $101M | $41M | $36M | $40M | $71M | $80M | $63M | · | $69M | $68M | $66M | · | $64M | |
| Capital Leases | $10M | $10M | $10M | $10M | $11M | $11M | $11M | $12M | $12M | $27M | · | $29M | $30M | $31M | · | $30M | |
| Deferred Tax | $8M | $8M | $8M | $8M | $8M | $7M | $7M | $8M | $7M | $7M | · | $5M | $7M | $7M | · | $9M | |
| Other Non-current Liabilities | $3M | $3M | $4M | $6M | $6M | $6M | $8M | $9M | $3M | $3M | · | $1M | $960.0K | $958.0K | · | $3M | |
| Total Liabilities | $661M | $629M | $626M | $660M | $589M | $572M | $563M | $590M | $634M | $623M | · | $603M | $589M | $218M | · | $217M | |
| Long-term Debt | · | · | $72M | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Total Debt | $50M | $50M | · | $52M | $52M | $52M | · | $51M | $103M | $102M | · | $101M | $101M | $103M | · | $102M | |
| Common Stock | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | $3M | · | $3M | $3M | $3M | · | $3M | |
| Paid-in Capital | $1.84B | $1.59B | $1.58B | $1.58B | $1.26B | $1.26B | $1.17B | $1.17B | $1.16B | $1.16B | · | $1.14B | $1.13B | $1.12B | · | $1.10B | |
| Retained Earnings | $-1.46B | $-1.38B | $-1.33B | $-1.29B | $-1.21B | $-1.17B | $-1.13B | $-1.06B | $-1.01B | $-956M | · | $-817M | $-728M | $-659M | · | $-589M | |
| AOCI | $-58M | $-60M | $-58M | $-59M | $-59M | $-54M | $-53M | $-57M | $-56M | $-56M | · | $-59M | $-52M | $-52M | $-58M | $-93M | |
| Stockholders' Equity | $324M | $149M | $199M | $229M | $-4M | $34M | $-7M | $56M | $97M | $147M | $208M | $269M | $353M | $413M | $476M | $421M | |
| Liabilities + Equity | $985M | $779M | $825M | $888M | $585M | $605M | $557M | $646M | $731M | $770M | · | $872M | $943M | $631M | · | $638M | |
| Shares Outstanding | 69,334,839 | 63,033,249 | 62,336,717 | 62,165,900 | 54,865,673 | 54,698,479 | 48,988,087 | 48,738,874 | 48,694,569 | 48,492,357 | 47,833,830 | 47,810,291 | 47,702,331 | 47,546,673 | 46,968,032 | 46,815,109 |
Flujo de Efectivo 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $5M | $3M | $3M | $4M | $4M | $5M | $4M | $3M | $3M | $3M | $4M | $3M | $3M | $3M | · | $2M | |
| Stock-based Comp | $5M | $5M | $5M | $4M | $5M | $4M | $5M | $3M | $7M | $7M | $7M | $11M | $9M | $8M | $12M | $8M | |
| Deferred Tax | $2M | $500.0K | $-391.0K | $1M | $400.0K | $500.0K | $871.0K | $-120.0K | · | · | $3M | $-69.0K | $163.0K | $-1M | $-231.0K | $-329.0K | |
| Operating Cash Flow | $-29M | $-38M | $-78M | $-16M | $-40M | $-44M | $-53M | $-37M | $-33M | $-61M | $-50M | $39M | $-57M | $-78M | $-55M | $-49M | |
| CapEx | $472.0K | $140.0K | $119.0K | $-66.0K | $260.0K | $126.0K | $40.0K | $380.0K | $604.0K | $2M | $2M | $2M | $1M | $2M | $5M | $4M | |
| Investing Cash Flow | $53M | $99M | $-441M | $27M | $73M | $20M | $-27M | $48M | $78M | $64M | $60M | $-314M | $46M | $3M | $-168M | $-5M | |
| Financing Cash Flow | $249M | $550.0K | $2M | $332M | $44.0K | $81M | $-7M | $-53M | · | · | $46.0K | $-8M | $370M | $131.0K | $601.0K | $301.0K | |
| Net Change in Cash | $273M | $60M | $-517M | $343M | $37M | $58M | $-93M | $-38M | $45M | $2M | $12M | $-284M | $360M | $-74M | $-212M | $-60M | |
| Free Cash Flow | · | $-38M | · | · | · | $-44M | · | · | · | $-63M | · | · | · | $-81M | · | · | |
| Levered FCF | · | · | · | · | · | · | · | · | · | $-79M | · | · | · | $-84M | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -893.7% | -1283.5% | · | -1379.0% | -833.6% | -2510.0% | · | -1759.0% | -395.6% | -639.1% | · | -5819.3% | -2686.8% | -1392.9% | · | -4107.5% | |
| Net Margin | -1387.8% | -1503.0% | · | -2175.9% | -716.8% | -2784.8% | · | · | · | -773.3% | · | · | · | -1450.3% | · | · | |
| Pretax Margin | -1356.2% | -1489.2% | · | -1942.8% | -708.7% | -2753.1% | · | -1941.8% | -497.5% | -765.6% | · | -6371.0% | -2820.4% | -1472.9% | · | -3325.5% | |
| EBITDA Margin | -893.7% | -1283.5% | · | -1379.0% | -833.6% | -2510.0% | · | -1759.0% | -395.6% | -639.1% | · | -5819.3% | -2686.8% | -1392.9% | · | -4107.5% | |
| ROA | -10.3% | -7.7% | · | -10.5% | -5.7% | -6.3% | · | · | · | -9.4% | · | · | · | -11.1% | · | · | |
| ROE | -50.6% | -58.5% | · | -56.6% | -81.0% | -48.4% | · | · | · | -23.4% | · | · | · | -16.1% | · | · | |
| ROIC | -14.3% | -23.2% | · | -20.4% | -92.7% | -46.7% | · | -37.6% | -22.4% | -22.0% | · | -22.1% | -14.3% | -14.1% | · | -11.3% |
Liquidez y Solvencia 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 10.0 | 10.4 | · | 7.1 | 10.0 | 12.0 | · | 6.5 | 7.4 | 9.4 | · | 10.1 | 11.1 | 6.7 | · | 7.3 | |
| Quick Ratio | 5.0 | 2.4 | · | 5.9 | 6.2 | 6.0 | · | 3.5 | 3.6 | 3.8 | · | 3.3 | 7.5 | 2.3 | · | 6.9 | |
| Debt / Equity | 0.2 | 0.3 | · | 0.2 | -13.0 | 1.5 | · | 0.9 | 1.1 | 0.7 | · | 0.4 | 0.3 | 0.3 | · | 0.2 | |
| LT Debt / Equity | 0.2 | 0.3 | · | 0.2 | -13.0 | 1.5 | · | 0.9 | 1.1 | 0.7 | · | 0.4 | 0.3 | 0.3 | · | 0.2 | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -3.4 | · | -5.3 | -9.5 | -20.8 | · | -19.4 |
Eficiencia 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | |
| Inventory Turnover | · | · | · | · | · | · | · | · | · | 0.0 | · | · | · | · | · | · | |
| Receivables Turnover | 1.4 | 0.8 | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 14
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $18M | $14M | · | $13M | $20M | $23M | · | $23M | $23M | $18M | · | $11M | $10M | $9M | · | $6M | |
| Net Income TTM | $-253M | $-215M | · | $-206M | $-182M | $-210M | · | · | · | · | · | · | · | · | · | · | |
| Market Cap | $3.19B | $1.03B | · | $3.63B | $765M | $580M | · | $240M | $218M | $252M | · | $321M | $547M | $958M | · | $878M | |
| Enterprise Value | $2.83B | $941M | · | $3.08B | $563M | $414M | · | $40M | $33M | $111M | · | $193M | $134M | $907M | · | $540M | |
| P/E | -11.1 | -4.4 | · | -15.4 | -3.9 | -2.5 | · | -0.9 | -0.8 | -0.8 | · | -1.1 | -2.3 | -4.5 | · | -5.1 | |
| P/S | 173.9 | 73.1 | · | 283.1 | 37.8 | 24.7 | · | 10.3 | 9.3 | 14.3 | · | 30.3 | 56.4 | 105.7 | · | 153.4 | |
| P/B | 9.9 | 6.9 | · | 15.9 | -191.1 | 17.2 | · | 4.3 | 2.2 | 1.7 | · | 1.2 | 1.5 | 2.3 | · | 2.1 | |
| P / Tangible Book | 13.5 | 18.9 | · | 28.1 | · | · | · | · | 14.2 | 4.1 | · | 1.7 | 2.0 | 2.9 | · | 2.6 | |
| P / Cash Flow | · | -26.9 | · | · | · | -13.1 | · | · | · | -4.2 | · | · | · | -12.2 | · | · | |
| P / FCF | · | -26.9 | · | · | · | -13.1 | · | · | · | -4.0 | · | · | · | -11.9 | · | · | |
| EV / EBITDA | -54.2 | -20.6 | · | -60.4 | -12.8 | -10.5 | · | -1.0 | -0.7 | -2.1 | · | -2.4 | -2.1 | -12.2 | · | -9.1 | |
| EV / FCF | · | -24.5 | · | · | · | -9.4 | · | · | · | -1.8 | · | · | · | -11.2 | · | · | |
| EV / Revenue | 154.1 | 66.7 | · | 240.6 | 27.8 | 17.7 | · | 1.7 | 1.4 | 6.3 | · | 18.2 | 13.8 | 100.1 | · | 94.3 | |
| Earnings Yield | -9.0% | -22.9% | · | -6.5% | -25.7% | -40.1% | · | -107.7% | -130.4% | -121.4% | · | -89.0% | -43.0% | -22.3% | · | -19.5% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $16M | $27M | $16M | $106M | $524M |
| Margen Operativo % | -1151.4% | -679.6% | -1785.5% | -134.4% | 59.3% |
| Beneficio neto | $-199M | $-240M | $-308M | $-127M | $330M |
| EPS Diluido | $-3.46 | $-4.92 | $-6.47 | $-2.71 | $7.04 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Deuda / Patrimonio | 0.2 | -7.6 | 0.5 | 0.2 | 0.2 |
| Ratio corriente | 10.4 | 9.7 | 8.8 | 6.3 | 17.1 |
| Ratio Rápido | 1.3 | 4.0 | 3.3 | 3.0 | 15.1 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-178M | $-186M | $-153M | $-163M | $271M |
Últimas noticias Noticias recientes que mencionan a esta empresa
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Propietarios institucionales (13F) 315 declarantes · $3.1B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 104 (+48 vs trimestre anterior) | 44 (-4 vs trimestre anterior) | 87 (-1 vs trimestre anterior) | 84 (+17 vs trimestre anterior) | -705K |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $309 881 409 | 6 727 777 | 10,06% | Acciones |
| RTW INVESTMENTS, LP | $181 548 806 | 3 941 572 | 5,89% | Acciones |
| STATE STREET CORP | $133 750 180 | 2 903 825 | 4,34% | Acciones |
| Aberdeen Group plc | $131 184 269 | 2 848 117 | 4,26% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $118 728 862 | 2 577 700 | 3,85% | Opción de compra |
| ORBIMED ADVISORS LLC | $83 252 805 | 1 807 486 | 2,70% | Acciones |
| Caption Management, LLC | $74 967 256 | 1 627 600 | 2,43% | Opción de compra |
| JENNISON ASSOCIATES LLC | $69 680 259 | 1 512 815 | 2,26% | Acciones |
| Boxer Capital Management, LLC | $69 241 998 | 1 503 300 | 2,25% | Acciones |
| GOLDMAN SACHS GROUP INC | $67 574 626 | 1 467 100 | 2,19% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $67 340 825 | 1 462 024 | 2,19% | Acciones |
| Two Seas Capital LP | $66 391 345 | 1 441 410 | 2,16% | Acciones |
| JANE STREET GROUP, LLC | $58 196 257 | 1 263 488 | 1,89% | Acciones |
| MAK CAPITAL ONE LLC | $56 748 269 | 1 232 051 | 1,84% | Acciones |
| MPM BIOIMPACT LLC | $56 462 881 | 1 225 855 | 1,83% | Acciones |
| FMR LLC | $54 494 830 | 1 183 127 | 1,77% | Acciones |
| CITADEL ADVISORS LLC | $46 069 212 | 1 000 200 | 1,50% | Opción de compra |
| Vestal Point Capital, LP | $43 066 100 | 935 000 | 1,40% | Acciones |
| MAVERICK CAPITAL LTD | $42 623 141 | 925 383 | 1,38% | Acciones |
| Integral Health Asset Management, LLC | $41 454 000 | 900 000 | 1,35% | Acciones |
| Longaeva Partners L.P. | $37 059 600 | 804 594 | 1,20% | Acciones |
| Nantahala Capital Management, LLC | $36 848 000 | 800 000 | 1,20% | Opción de compra |
| VANGUARD CAPITAL MANAGEMENT LLC | $35 916 621 | 779 779 | 1,17% | Acciones |
| Fiera Capital Corp | $35 628 515 | 773 524 | 1,16% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $32 619 201 | 707 810 | 1,06% | Acciones |
| CITIGROUP INC | $30 629 900 | 665 000 | 0,99% | Opción de compra |
| First Turn Management, LLC | $28 047 086 | 608 925 | 0,91% | Acciones |
| Point72 Asset Management, L.P. | $27 922 125 | 606 212 | 0,91% | Acciones |
| CITADEL ADVISORS LLC | $27 484 002 | 596 700 | 0,89% | Opción de venta |
| Balyasny Asset Management L.P. | $27 017 967 | 586 582 | 0,88% | Acciones |
| Kinetic Partners Management, LP | $26 760 860 | 581 000 | 0,87% | Acciones |
| TWO SIGMA ADVISERS, LP | $26 571 872 | 1 110 400 | 0,86% | Acciones |
| 683 Capital Management, LLC | $26 484 501 | 575 000 | 0,86% | Acciones |
| TUDOR INVESTMENT CORP ET AL | $25 254 698 | 548 300 | 0,82% | Opción de compra |
| JANE STREET GROUP, LLC | $25 231 668 | 547 800 | 0,82% | Opción de compra |
| GILDER GAGNON HOWE & CO LLC | $24 456 893 | 530 979 | 0,79% | Acciones |
| Invesco Ltd. | $24 439 021 | 530 591 | 0,79% | Acciones |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | $24 028 443 | 521 677 | 0,78% | Acciones |
| Assenagon Asset Management S.A. | $23 653 192 | 513 530 | 0,77% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $22 887 076 | 496 897 | 0,74% | Acciones |
| Nantahala Capital Management, LLC | $20 987 700 | 455 660 | 0,68% | Acciones |
| Voss Capital, LP | $20 743 628 | 450 361 | 0,67% | Acciones |
| CITADEL ADVISORS LLC | $20 275 658 | 440 201 | 0,66% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $19 349 806 | 420 100 | 0,63% | Opción de venta |
| Rubric Capital Management LP | $18 819 241 | 408 581 | 0,61% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $18 577 748 | 403 338 | 0,60% | Acciones |
| READYSTATE ASSET MANAGEMENT LP | $18 469 553 | 400 989 | 0,60% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $17 024 098 | 369 607 | 0,55% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $15 804 384 | 343 126 | 0,51% | Acciones |
| Creek Drive Management Group LLC | $15 522 220 | 337 000 | 0,50% | Acciones |
| TUDOR INVESTMENT CORP ET AL | $15 148 627 | 328 889 | 0,49% | Acciones |
| Privium Fund Management B.V. | $15 122 511 | 328 322 | 0,49% | Acciones |
| ADAR1 Capital Management, LLC | $14 954 392 | 324 672 | 0,49% | Acciones |
| 683 Capital Management, LLC | $14 564 172 | 316 200 | 0,47% | Opción de compra |
| BRAIDWELL LP | $13 894 091 | 301 652 | 0,45% | Acciones |
| DIADEMA PARTNERS LP | $13 771 940 | 299 000 | 0,45% | Opción de venta |
| Squarepoint Ops LLC | $12 910 618 | 280 300 | 0,42% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $11 249 602 | 244 238 | 0,37% | Acciones |
| DIADEMA PARTNERS LP | $10 842 524 | 235 400 | 0,35% | Opción de compra |
| FourWorld Capital Management LLC | $10 133 200 | 220 000 | 0,33% | Opción de compra |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $10 018 000 | 217 500 | 0,33% | Acciones |
| Parkman Healthcare Partners LLC | $9 588 310 | 208 170 | 0,31% | Acciones |
| D. E. Shaw & Co., Inc. | $9 563 392 | 207 629 | 0,31% | Acciones |
| TUDOR INVESTMENT CORP ET AL | $9 396 240 | 204 000 | 0,31% | Opción de venta |
| BANK OF AMERICA CORP /DE/ | $9 386 844 | 203 796 | 0,30% | Acciones |
| Caption Management, LLC | $9 262 666 | 201 100 | 0,30% | Opción de venta |
| Affinity Asset Advisors, LLC | $9 212 000 | 200 000 | 0,30% | Opción de compra |
| MILLENNIUM MANAGEMENT LLC | $9 202 788 | 199 800 | 0,30% | Opción de compra |
| Diametric Capital, LP | $9 084 966 | 197 242 | 0,29% | Acciones |
| BARCLAYS PLC | $8 686 916 | 188 600 | 0,28% | Opción de compra |
| PICTON MAHONEY ASSET MANAGEMENT | $8 346 765 | 181 215 | 0,27% | Acciones |
| Affinity Asset Advisors, LLC | $8 060 500 | 175 000 | 0,26% | Acciones |
| Trexquant Investment LP | $7 883 123 | 171 149 | 0,26% | Acciones |
| PERCEPTIVE ADVISORS LLC | $7 738 080 | 168 000 | 0,25% | Acciones |
| VANGUARD GROUP INC | $7 660 137 | 320 106 | 0,25% | Acciones |
| Nantahala Capital Management, LLC | $7 438 690 | 161 500 | 0,24% | Opción de venta |
| FLAX POND CAPITAL, LLC | $7 218 800 | 156 726 | 0,23% | Acciones |
| AMERIPRISE FINANCIAL INC | $7 002 133 | 152 022 | 0,23% | Acciones |
| Casdin Capital, LLC | $6 909 000 | 150 000 | 0,22% | Acciones |
| LMR Partners LLP | $6 909 000 | 150 000 | 0,22% | Opción de compra |
| MARSHALL WACE, LLP | $6 615 321 | 143 624 | 0,21% | Acciones |
| WOLVERINE TRADING, LLC | $6 599 340 | 111 100 | 0,21% | Opción de compra |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6 498 744 | 141 093 | 0,21% | Acciones |
| UBS Group AG | $6 110 412 | 132 662 | 0,20% | Acciones |
| CITIGROUP INC | $5 893 101 | 127 944 | 0,19% | Acciones |
| SIG BROKERAGE, LP | $5 872 650 | 127 500 | 0,19% | Opción de compra |
| ENVESTNET ASSET MANAGEMENT INC | $5 830 106 | 126 576 | 0,19% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $5 613 286 | 121 869 | 0,18% | Acciones |
| Hudson Bay Capital Management LP | $5 527 200 | 120 000 | 0,18% | Acciones |
| WOLVERINE TRADING, LLC | $5 482 620 | 92 300 | 0,18% | Opción de venta |
| NAN FUNG TRINITY (HK) LTD | $5 319 654 | 115 494 | 0,17% | Acciones |
| SIMPLEX TRADING, LLC | $5 076 687 | 110 219 | 0,16% | Acciones |
| SILVERARC CAPITAL MANAGEMENT, LLC | $4 836 300 | 105 000 | 0,16% | Acciones |
| Ghisallo Capital Management LLC | $4 606 000 | 100 000 | 0,15% | Acciones |
| Pekin Hardy Strauss, Inc. | $4 341 155 | 94 250 | 0,14% | Acciones |
| Swiss National Bank | $4 334 246 | 94 100 | 0,14% | Acciones |
| JANE STREET GROUP, LLC | $4 209 884 | 91 400 | 0,14% | Opción de venta |
| STEMPOINT CAPITAL LP | $4 058 577 | 88 115 | 0,13% | Acciones |
| FourWorld Capital Management LLC | $4 007 220 | 87 000 | 0,13% | Acciones |
| Marex Group Ltd | $3 753 890 | 81 500 | 0,12% | Acciones |
Informantes de la empresa 28 insiders · 17 directivos · 12 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Matthew C Kapusta | CEO, Managing Director | 2 de julio de 2026 M | 519 227 | 0 | 21 | $-22 247 399 |
| Christian Klemt | Chief Financial Officer | 4 de marzo de 2026 A | 226 581 | 0 | 5 | $-1 326 871 |
| Ricardo Dolmetsch | President, R&D | 18 de septiembre de 2023 S | 163 404 | 0 | 0 | $0 |
| Pierre Caloz | Chief Operating Officer | 17 de junio de 2024 S | 115 707 | 0 | 0 | $0 |
| Scott T. Mcmillan | Chief Operating Officer | 28 de enero de 2019 S | 20 432 | 0 | 0 | $0 |
| Walid Abi-Saab | Chief Medical Officer | 30 de junio de 2026 M | 148 235 | 0 | 7 | $-2 611 134 |
| Jeannette Potts | Chief Legal Officer | 15 de junio de 2026 S | 133 246 | 0 | 3 | $-261 172 |
| Kylie O'Keefe | Chief Customer & Strat Officer | 11 de junio de 2026 S | 108 864 | 0 | 1 | $-431 228 |
| Alexander Edward Kuta III | Executive VP, Operations | 7 de marzo de 2023 S | 90 381 | 0 | 0 | $0 |
| Sander Van Deventer | EVP, Research & Product Dev. | 27 de febrero de 2020 A | 61 599 | 0 | 0 | $0 |
| Steven Zelenkofske | Chief Medical Officer | 6 de junio de 2018 S | 159 458 | 0 | 0 | $0 |
| Jonathan Garen | Chief Business Officer | 26 de enero de 2018 A | 93 638 | 0 | 0 | $0 |
| Paul E Firuta | Chief Commercial Officer | 26 de enero de 2018 A | 93 817 | 0 | 0 | $0 |
| Maria E Cantor | SVP, Investor Rel. & Comm. | 26 de enero de 2018 A | 92 439 | 0 | 0 | $0 |
| Harald Petry | Chief Scientific Officer | 29 de junio de 2017 M | 0 | 0 | 0 | $0 |
| Christian Meyer | Chief Medical Officer | 27 de enero de 2017 A | — | 0 | 0 | $0 |
| Maiken Keson-Brookes | General Counsel | 27 de enero de 2017 A | — | 0 | 0 | $0 |
| Jack Kaye | Consejero | 30 de junio de 2026 M | 25 996 | 0 | 9 | $-2 693 581 |
| Madhavan Balachandran | Consejero | 17 de junio de 2026 M | 43 254 | 0 | 5 | $-858 916 |
| Rachelle Suzanne Jacques | Consejero | 10 de junio de 2026 A | 33 903 | 0 | 1 | $-53 931 |
| Jeremy P. Springhorn | Consejero | 10 de junio de 2026 A | 43 251 | 0 | 1 | $-53 931 |
| Robert Gut | Consejero | 10 de junio de 2026 A | 32 259 | 0 | 9 | $-1 757 850 |
| David D. Meek | Consejero | 10 de junio de 2026 A | 39 747 | 0 | 1 | $-53 931 |
| Leonard E Post | Consejero | 10 de junio de 2026 A | 35 494 | 0 | 1 | $-53 931 |
| Paula Soteropoulos | Consejero | 13 de junio de 2024 S | 20 203 | 0 | 0 | $0 |
| Philip Astley-Sparke | Consejero | 2 de marzo de 2021 S | 9 946 | 0 | 0 | $0 |
| David Schaffer | Consejero | 27 de febrero de 2020 A | 46 978 | 0 | 0 | $0 |
| William Lewis | Consejero | 27 de enero de 2017 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 1 tenencia
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Coller Investment Management Limited, Coller International General Partner V, L.P, Coller International Partners V-A, L.P ×4 presentaciones | 3 de abril de 2019 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 14 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| GNOM · Global X Funds | 1,59% | 31 188 NS | 31 de mayo de 2026 | N-PORT |
| PTH · Invesco Exchange-Traded Fund Trust | 1,54% | 81 827 SH | 8 de agosto de 2026 | Diario |
| DWAS · Invesco Exchange-Traded Fund Trust … | 0,47% | 45 896 SH | 8 de agosto de 2026 | Diario |
| LABU · Direxion Shares ETF Trust | 0,37% | 97 163 NS | 30 de abril de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,20% | 3 429 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,20% | 416 066 SH | 8 de agosto de 2026 | Diario |
| ESIM · Strategy Shares | 0,11% | 867 NS | 30 de abril de 2026 | N-PORT |
| ISCV · iShares Trust | 0,09% | 14 177 SH | 8 de agosto de 2026 | Diario |
| ISCB · iShares Trust | 0,05% | 2 897 SH | 8 de agosto de 2026 | Diario |
| VXF · VANGUARD INDEX FUNDS | 0,03% | 757 841 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,03% | 141 093 SH | 8 de agosto de 2026 | Diario |
| WSML · iShares Trust | 0,02% | 2 372 SH | 8 de agosto de 2026 | Diario |
| ITOT · iShares Trust | 0,00% | 89 144 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,00% | 52 NS | 31 de mayo de 2026 | N-PORT |