SLS SELLAS Life Sciences Group, Inc. - Common Stock

NASDAQ · Biotechnology · Ver en SEC EDGAR ↗
$13,06
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 11, 2026

Acerca de SELLAS Life Sciences Group, Inc. - Common Stock Descripción general de la empresa de Wikipedia

Galena Biopharma, Inc. was a publicly traded pharmaceutical company based in San Ramon, California. The company was founded in Worcester, Massachusetts. In 2011, it moved to Oregon, and in 2015 moved to San Ramon, California. Mark Schwartz was the company's president and chief executive officer. As of December 29, 2017, the company was acquired by Sellas Life Sciences Group Ltd. through a reverse merger transaction. Galena Biopharma was renamed to Sellas Life Sciences Group, Inc..

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Galena Biopharma, Inc. (originally RXi Pharmaceuticals) was a publicly traded pharmaceutical company based in San Ramon, California. The company was founded in Worcester, Massachusetts. In 2011, it moved to Oregon, and in 2015 moved to San Ramon, California. Mark Schwartz was the company's president and chief executive officer. As of December 29, 2017, the company was acquired by Sellas Life Sciences Group Ltd. through a reverse merger transaction. Galena Biopharma was renamed to Sellas Life Sciences Group, Inc. (Nasdaq: SLS).

History

In November 2006, Argonaut Pharmaceuticals, Inc. changed the name to RXi Pharmaceuticals Corporation. RXi was a subsidiary of CytRx Corp., which provided $15 million in financing in April 2007. RXi was founded in part by Nobel Prize winner Craig Mello. In September 2007, RXi signed a licensing deal with TriLink Biotechnologies, a competitor in the RNA interference (RNAi) field, in which RXi would pay TriLink to use three of TriLink's technologies.

In March 2011, the company announced the planned acquisition of Arizona-based Apthera, Inc. for $7 million. The acquisition included the breast cancer drug NeuVax. In June 2011, NeuVax was approved by the United States Food and Drug Administration to start a stage three clinical trial.

In September 2011, the company separated its cancer therapies division. It was renamed Galena Biopharma Inc and moved to Lake Oswego, Oregon. RXi became a subsidiary of Galena and retained RNAi technologies. RXi Pharmaceuticals remained in Massachusetts as a publicly traded company. In January 2014, Galena bought Mills Pharmaceuticals. In April 2014, the company headquarters moved to Portland.

In November 2011, the company partnered with Genentech to combine drugs from each company for a cancer treatment. Galena is currently studying the combination of NeuVax and Herceptin in phase II trials.

Leadership

In March 2011, president and CEO Noah Beerman were replaced by Mark Ahn, and in August 2014, Ahn resigned and was replaced by Mark Schwartz. On January 31, 2017, Galena announced the resignation of Mark Schwartz effective that day, and reported in the same press release that it would be exploring strategic alternatives to maximize shareholder value going forward.

Stock

RXi went public in March 2008. CytRx retained 49% ownership of RXi's stock and gave shares of RXi to existing shareholders. Trading began on the Nasdaq market on March 12, 2008, under the ticker symbol of RXII. Fidelity Investments invested $8.5 million in the company in May 2008, followed by a $25 million private-equity investment by Yorkville in February 2009. In 2010, RXi received a National Institutes of Health grant of $600,000. By August 2010, the company had 30 employees. In April 2011, RXi raised about $12 million from a stock offering and received $580,000 in grants from the National Institutes of Health. The company reported a loss of $11.5 million loss for 2011.

In November 2012, an anonymous internet report caused Galena stock to decline. The company filed a lawsuit claiming the report was false and attempted to manipulate the stock. In 2014, Galena's involvement in a fraudulent stock promotion scheme was exposed. On February 1, 2014, analyst Matt Gravitt published an article that revealed Galena had paid MissionIR, DreamTeam brand, to promote Galena's stock. Galena's stock fell 20% following this revelation that received a heated response, and was one of the three most read articles in Seeking Alpha's history. Over the next few weeks, more revelations came out and the company admitted their stock promotion relationship and insider selling. Galena then disclosed that the SEC was investigation their relationship with The DreamTeam Group. By March 2014, five lawsuits were filed against Galena and several of its officers alleging that the company used misleading articles to boost stock prices. Motley Fool, discussing the 23% stock price drop during March 2015, noted there was stock dilution from the offering and also that Abstral's sales were below Galena's estimates from late 2013. Discussing the Motley Fool article, Portland Business Journal also noted the ongoing insider-trading lawsuits as a factor in the stock price. A few days later, Zacks Investment Research said Galena could be a "great candidate" to beat its earnings. In response, Galena's CEO said there were many positive aspects to the company, and that the lawsuits weren't a worry as they should get covered under Directors and officers liability insurance. The company moved to San Ramon, California, in the Bay Area in 2015.

Stock promotion scandal

The revelation that Galena was engaging in fraudulent stock promotion without adequate disclosure led to the investigation of other biotech companies who engaged in similar activities. Richard Pearson, an investor who went undercover to investigate the stock promotion firms, wrote an exposé on DreamTeam and its ties to articles about Galena, CytRx, and other companies on media websites. In April 2017, the Securities and Exchange Commission announced enforcement actions against 27 individuals and entities behind various alleged stock promotion schemes. Fraud charges were filed against three public companies, seven stock promotion or communications firms, and two company CEOs; also on this hit list are six individuals and nine writers.

Merger with Sellas Life Sciences

In 2017, Galena Biopharma Inc. announced a merger "with privately-held oncology company Sellas Life Sciences Group Ltd. in an all-stock transaction." The combined company was Sellas Life Science Group. The newly merged companies focused on the development of novel treatments for cancer.

Products

Galena acquired the experimental breast cancer drug NeuVax in 2011 and are currently in phase II trials to combine the drug with Genentech's Herceptin.

In 2013, Galena began selling its first developed drug, an analgesic for cancer pain named Abstral Sublingual.

Anagrelide controlled-released (GALE-401) was approved by the FDA for phase III clinical trials for the treatment of essential thrombocytosis in December 2016.

GALE-301 and GALE-302 are immunotherapies in phase I and II trials for ovarian and breast cancers.

== References ==

Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗

Wikidata ↗

SLS Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas

Precio
$13.06
Capitalización Bursátil
$2.37B
P/E (TTM)
-61.9
BPA (TTM)
$-0.25
Ingresos (TTM)
$0
Rendimiento div.
ROE
-55.4%
Deuda/Capital
Rango 52S
$1 – $16

SLS Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista

Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA

Ingresos y Beneficio Neto $0
5-point trend, +0.00
2019-12-31 2023-12-31
BPA $-0.25
6-point trend, +88.2%
2020-12-31 2025-12-31
Flujo de caja libre
2016-12-31 2016-12-31
Márgenes

Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?

Métrica
Tendencia a 5 años
SLS
Mediana de Pares
P/E (TTM)
5-point trend, -265.4%
-61.9
55.4
P/B (P/C)
5-point trend, +88.5%
33.4
6.4

Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC

Métrica
Tendencia a 5 años
SLS
Mediana de Pares
ROA
5-point trend, +4.0%
-54.9%
-32.7%
ROE
5-point trend, +37.2%
-55.4%
-37.9%
ROIC
5-point trend, +67.5%
-39.9%

Salud financiera Deuda, liquidez, solvencia — solidez del balance general

Métrica
Tendencia a 5 años
SLS
Mediana de Pares
Current Ratio (Ratio corriente)
5-point trend, +131.7%
10.7
9.7
Quick Ratio (Ratio Rápido)
5-point trend, +138.7%
10.2

Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años

Métrica
Tendencia a 5 años
SLS
Mediana de Pares

Métricas por acción BPA, valor contable por acción, flujo de caja por acción, dividendo por acción

Métrica
Tendencia a 5 años
SLS
Mediana de Pares
EPS (Diluted) (BPA (Diluido))
5-point trend, +81.3%
$-0.25

Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar

Métrica
Tendencia a 5 años
SLS
Mediana de Pares

SLS Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista

COMPRA 6 analistas
  • Compra fuerte 1 16,7%
  • Compra 4 66,7%
  • Mantener 1 16,7%
  • Venta 0 0,0%
  • Venta fuerte 0 0,0%

Precio objetivo a 12 meses

2 analistas · 2026-08-14
Objetivo mediano $27.50 +110,5%
Objetivo medio $27.50 +110,5%

Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados

Sorpresa Media
0.02%
Período EPS Actual EPS est. Sorpresa
31 de marzo de 2026 $-0.05 $-0.04 -0.01%
31 de diciembre de 2025 $-0.05 $-0.07 0.02%
30 de septiembre de 2025 $-0.06 $-0.07 0.01%
30 de junio de 2025 $-0.07 $-0.08 0.01%
31 de marzo de 2025 $-0.07 $-0.11 0.04%
31 de diciembre de 2024 $-0.08 $-0.11 0.03%

Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector

Ticker Capitalización Bursátil P/E Ingresos interanuales Margen Neto ROE Margen Bruto
SLS $577M -15.1 -55.4%
NRIX $1.80B -5.8 53.9% -314.9% -53.6%
BEAM $2.82B -34.2 120.0% -57.2% -7.0%
KOD $1.73B -6.5 -202.0%
RARE $2.22B -3.9 20.2% -85.4% -1613.2%
BCRX $1.66B 6.4 94.1% 30.2% -97.6%
COAG
KLRA
CDNA $959M -47.1 13.8% -5.6% -6.8%
PGEN $1.48B -3.1 146.7% -2588.2% 3159.1%

Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja

Estado de resultados 15
Datos anuales de Estado de resultados para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue 6-point trend, -100.0% · · $0 $1M $8M $2M $0 · · · · $9M
Cost of Revenue 7-point trend, -100.0% $0 $0 $0 $100.0K $200.0K $0 · · · · · $1M
R&D Expense 6-point trend, +37.6% · · · · $16M $9M $7M $9M $6M $11M · ·
SG&A Expense 10-point trend, +166.8% $12M $12M $14M $13M $11M $10M $10M $13M $15M $5M · ·
Operating Expenses 12-point trend, -35.6% $28M $32M $38M $43M $33M $19M $20M $31M $23M $32M $34M $44M
Operating Income 11-point trend, +35.6% $-28M $-32M $-38M $-42M $-25M $-17M $-20M · $-23M $-16M $-34M $-44M
Other Non-op 12-point trend, +730.0% $1M $632.0K $529.0K $649.0K $4M $208.0K $-19M $-29M $-24M $5M $509.0K $170.0K
Pretax Income 12-point trend, +5.0% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-29M $-24M $-18M $-39M $-28M
Income Tax 12-point trend, +0.00 $0 $0 $0 $0 $-237.0K $-17.0K $-81.0K $-1M $300.0K $1.0K $365.0K $0
Net Income 12-point trend, +26.6% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-28M $-24M $-18M $-64M $-37M
EPS (Basic) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
EPS (Diluted) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
Shares (Basic) 6-point trend, +1267.1% 109,051,215 61,202,412 27,777,111 19,395,709 15,481,113 7,977,104 · · · · · ·
Shares (Diluted) 6-point trend, +1267.1% 109,051,215 61,202,412 27,777,111 19,395,709 15,481,113 7,977,104 · · · · · ·
EBITDA 8-point trend, +10.9% $-28M $-32M $-38M $-42M $-25M $-17M · · $-23M $-32M · ·
Balance general 22
Datos anuales de Balance general para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +203.6% $72M $14M $3M $17M $21M $35M $7M $5M $2M $6M $1M $24M
Receivables 2-point trend, -100.0% · · · · $0 · · · · · · $2M
Inventory 2-point trend, -100.0% · · · · · · · · · · $0 $655.0K
Prepaid Expense 12-point trend, +168.2% $3M $2M $542.0K $531.0K $2M $395.0K $557.0K $387.0K $337.0K $332.0K $1M $1M
Current Assets 12-point trend, +44.4% $75M $16M $3M $18M $23M $37M $8M $6M $13M $6M $54M $52M
PP&E (Net) 3-point trend, -30.2% · · · · · · · · · $199.0K $335.0K $285.0K
Goodwill 12-point trend, -67.5% $2M $2M $2M $2M $2M $2M $2M $2M $2M $6M $6M $6M
Total Assets 12-point trend, -2.7% $78M $19M $6M $21M $26M $46M $17M $17M $34M $6M $82M $80M
Accounts Payable 12-point trend, +56.3% $3M $4M $6M $3M $2M $5M $4M $4M $12M $840.0K $2M $2M
Accrued Liabilities 12-point trend, -60.3% $4M $5M $8M $6M $3M $2M $1M $2M $3M $4M $5M $9M
Current Liabilities 12-point trend, -74.2% $7M $10M $14M $16M $5M $12M $5M $6M $25M $6M $57M $27M
Capital Leases 8-point trend, +457000.00 $457.0K $457.0K $460.0K $573.0K $610.0K $825.0K $0 $0 · · · ·
Deferred Tax 5-point trend, -100.0% · · · · $0 $239.0K $262.0K $357.0K $2M · · ·
Total Liabilities 12-point trend, -82.8% $7M $10M $14M $16M $6M $18M $11M $12M $31M $11M $69M $43M
Long-term Debt 4-point trend, -100.0% · · · · · · · $0 $11M · $5M $8M
Total Debt 2-point trend, -33.0% · · · · · · · · $11M $16M · ·
Common Stock 12-point trend, +25.0% $15.0K $7.0K $3.0K $2.0K $2.0K $1.0K $1.0K $1.0K $1.0K $2.0K $15.0K $12.0K
Retained Earnings 10-point trend, -803.6% $-275M $-248M $-217M $-180M $-139M $-118M $-101M $-82M $-54M $-30M · ·
Treasury Stock Flat — no change across 3 periods · · · · · · · · · $4M $4M $4M
Stockholders' Equity 12-point trend, +91.2% $71M $9M $-8M $5M $20M $28M $6M $5M $2M $-5M $-12M $37M
Liabilities + Equity 12-point trend, -2.7% $78M $19M $6M $21M $26M $46M $17M $17M $34M $6M $82M $80M
Shares Outstanding 12-point trend, +39.9% 153,103,459 73,977,459 32,132,890 21,005,405 15,895,637 14,254,554 5,080,100 440,529 5,766,891 1,268,489 8,095,337 109,425,701
Flujo de Efectivo 17
Datos anuales de Flujo de Efectivo para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
D&A 3-point trend, -96.5% · · · · · · · · · $3.0K $107.0K $86.0K
Stock-based Comp 12-point trend, -58.1% $2M $2M $2M $2M $1M $578.0K $573.0K $395.0K $3M $354.0K $2M $5M
Deferred Tax 9-point trend, +0.00 · · · $0 $-239.0K $-22.0K $-95.0K $-1M $39.0K $-41.0K $365.0K $0
Amort. of Intangibles 3-point trend, -100.0% · · · · · · · $0 $2M · · $440.0K
Other Non-cash · · · · · · · · · $-24M · ·
Operating Cash Flow 12-point trend, +33.8% $-28M $-35M $-31M $-24M $-26M $-10M $-18M $-30M $-11M $-12M $-48M $-43M
CapEx 3-point trend, -89.5% · · · · · · · · · $6.0K $153.0K $57.0K
Investing Cash Flow 9-point trend, +100.0% · $0 $-6M $-4M $0 · · $0 $12M $-85.0K $10M $-6M
Debt Issued 3-point trend, +1500000.00 · · · · · · · · · $2M $0 $0
Net Debt Issued 2-point trend, -100.0% · · · · · · $0 · · $18M · ·
Stock Issued 11-point trend, -100.0% · $0 $289.0K $1M $9M $30M $16M $22M $6M $34M $47M $11M
Net Stock Activity 8-point trend, -100.0% · $0 $289.0K $1M $9M $30M $16M · $6M $34M · ·
Dividends Paid 3-point trend, +0.00 · · · · · · $0 $487.0K $0 · · ·
Financing Cash Flow 12-point trend, +255.7% $86M $47M $22M $24M $12M $38M $20M $23M $6M $16M $44M $24M
Net Change in Cash 12-point trend, +339.9% $58M $11M $-15M $-4M $-14M $28M $2M $-7M $7M $5M $6M $-24M
Taxes Paid Flat — no change across 2 periods $0 $0 · · · · · · · · · ·
Free Cash Flow · · · · · · · · · $-45M · ·
Rentabilidad 7
Datos anuales de Rentabilidad para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Operating Margin 4-point trend, -184.1% · · · -4195.0% -332.8% -893.8% · · 4986.8% · · ·
Net Margin 5-point trend, -180.3% · · · -4130.1% -272.4% -881.9% -16349.1% · 5141.6% · · ·
Pretax Margin 5-point trend, -181.2% · · · -4130.1% -275.5% -882.8% -16417.0% · 5086.8% · · ·
EBITDA Margin 4-point trend, -184.1% · · · -4195.0% -332.8% -893.8% · · 4986.8% · · ·
ROA 9-point trend, -72.6% -54.9% -240.8% -274.9% -174.9% -57.2% -53.5% -115.1% · -118.9% -31.8% · ·
ROE 9-point trend, +80.7% -55.4% -243.6% 632.7% -473.4% -88.2% -93.3% -340.3% · 1623.1% -287.3% · ·
ROIC 8-point trend, +44.8% -39.9% -332.9% 474.8% -864.8% -122.9% -60.7% · · -178.3% -72.3% · ·
Liquidez y Solvencia 4
Datos anuales de Liquidez y Solvencia para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Current Ratio 9-point trend, +768.9% 10.7 1.7 0.2 1.1 4.6 3.0 1.6 · 0.5 1.2 · ·
Quick Ratio 9-point trend, +1619.8% 10.2 1.5 0.2 1.1 4.3 2.9 1.4 · 0.1 0.6 · ·
Debt / Equity 2-point trend, +827.7% · · · · · · · · 5.3 0.6 · ·
LT Debt / Equity · · · · · · · · 1.3 · · ·
Eficiencia 1
Datos anuales de Eficiencia para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Asset Turnover 6-point trend, +100.0% · · 0.0 0.0 0.2 0.1 0.0 · -0.0 · · ·
Por Acción 5
Datos anuales de Por Acción para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, -75.5% $0.46 $0.13 $-0.25 $0.23 $1.28 $1.96 $1.20 · $0.36 $1.89 · ·
Revenue / Share 3-point trend, -100.0% · · $0.00 $0.05 $0.49 · · · · · · ·
Cash Flow / Share 5-point trend, +84.5% $-0.26 $-0.58 $-1.13 $-1.23 $-1.68 · · · · · · ·
Cash / Share 9-point trend, -60.6% $0.47 $0.19 $0.08 $0.82 $1.34 $2.48 $1.43 · $0.40 $1.19 · ·
EPS (TTM) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
Tasas de Crecimiento 1
Datos anuales de Tasas de Crecimiento para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue YoY 2-point trend, -128.9% · · · -86.8% 300.0% · · · · · · ·
Valoración (TTM) 17
Datos anuales de Valoración (TTM) para SLS
Métrica Tendencia 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -100.0% $0 $0 $0 $1M $8M $2M $0 $10M $10M $10M $10M $9M
Net Income TTM 12-point trend, +26.6% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-28M $-24M $-18M $-64M $-37M
Market Cap 9-point trend, -98.7% $577M $77M $34M $50M $88M $83M $22M · $2.25B $44.20B · ·
Enterprise Value 2-point trend, -94.9% · · · · · · · · $2.26B $44.20B · ·
P/E 6-point trend, -447.6% -15.1 -2.1 -0.8 -1.1 -4.1 -2.8 · · · · · ·
P/S 5-point trend, -98.9% · · · 49.6 11.6 43.6 · · 223.1 4384.0 · ·
P/B 9-point trend, -99.5% 8.1 8.1 -4.3 10.2 4.3 3.0 3.6 · 1086.5 1542.5 · ·
P / Tangible Book 5-point trend, +163.3% 8.4 10.2 · 16.9 4.8 3.2 · · · · · ·
P / Cash Flow 9-point trend, +97.9% -20.3 -2.2 -1.1 -2.1 -3.4 -8.0 -1.2 · -204.7 -984.2 · ·
P / FCF · · · · · · · · · -984.0 · ·
EV / EBITDA 2-point trend, +93.0% · · · · · · · · -98.0 -1393.3 · ·
EV / FCF · · · · · · · · · -984.0 · ·
EV / Revenue 2-point trend, -94.9% · · · · · · · · 223.9 4383.9 · ·
Dividend Yield Flat — no change across 2 periods · · · · · · 0.00% · 0.00% · · ·
Earnings Yield 6-point trend, +81.7% -6.6% -48.1% -126.4% -90.2% -24.2% -36.3% · · · · · ·
Payout Ratio · · · · · · 0.00% · · · · ·
Annual Payout 3-point trend, +0.00 · · · · · · $0 $487.0K $0 · · ·

Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años

Estado de resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ingresos $0$1M$8M
Margen Operativo % -4195.0%-332.8%
Beneficio neto $-27M$-31M$-37M$-41M$-21M
EPS Diluido $-0.25$-0.50$-1.34$-2.13$-1.34
Balance general
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ratio corriente 10.71.70.21.14.6
Ratio Rápido 10.21.50.21.14.3

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Propietarios institucionales (13F) 231 declarantes · $1.2B total · A fecha de 30 de junio de 2026

Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.

Actividad institucional — Q2 2026 vs trimestre anterior
Nuevas posiciones Posiciones cerradas Aumentado Disminuido Cambio neto de acciones
87 (+24 vs trimestre anterior) 19 (+4 vs trimestre anterior) 70 (+12 vs trimestre anterior) 38 (+15 vs trimestre anterior) +39.9M

Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.

Institución Valor Acciones % de 13F rastreadas Tipo
STATE STREET CORP $191 829 196 12 996 558 15,97% Acciones
VANGUARD CAPITAL MANAGEMENT LLC $121 417 310 8 226 105 10,11% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $105 640 272 7 157 200 8,79% Opción de compra
Anson Funds Management LP $66 420 000 4 500 000 5,53% Acciones
CITADEL ADVISORS LLC $64 157 292 4 346 700 5,34% Opción de compra
GEODE CAPITAL MANAGEMENT, LLC $61 905 400 4 193 009 5,15% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $61 832 592 4 189 200 5,15% Opción de venta
CITADEL ADVISORS LLC $33 333 984 2 258 400 2,77% Opción de venta
VANGUARD PORTFOLIO MANAGEMENT LLC $31 897 821 2 161 099 2,66% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $30 266 812 2 050 597 2,52% Acciones
JONES FINANCIAL COMPANIES LLLP $28 553 511 2 304 561 2,38% Acciones
VANGUARD GROUP INC $27 868 421 7 392 154 2,32% Acciones
Anson Funds Management LP $27 245 484 1 845 900 2,27% Opción de venta
PERCEPTIVE ADVISORS LLC $22 140 000 1 500 000 1,84% Opción de venta
VANGUARD FIDUCIARY TRUST CO $19 707 050 1 335 166 1,64% Acciones
Sio Capital Management, LLC $18 165 132 1 230 700 1,51% Opción de venta
BNP PARIBAS FINANCIAL MARKETS $15 823 045 1 072 022 1,32% Acciones
MILLENNIUM MANAGEMENT LLC $13 372 560 906 000 1,11% Opción de venta
BARCLAYS PLC $11 831 616 801 600 0,98% Opción de venta
Anson Funds Management LP $11 808 000 800 000 0,98% Opción de compra
BNP PARIBAS FINANCIAL MARKETS $11 734 200 7 950 0,98% Opción de venta
JANE STREET GROUP, LLC $11 058 192 749 200 0,92% Opción de compra
MORGAN STANLEY $9 922 380 672 248 0,83% Acciones
BANK OF AMERICA CORP /DE/ $9 150 359 619 943 0,76% Acciones
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $8 339 518 565 008 0,69% Acciones
JANE STREET GROUP, LLC $7 462 700 505 603 0,62% Acciones
Balyasny Asset Management L.P. $7 380 000 500 000 0,61% Opción de venta
LMR Partners LLP $6 642 000 450 000 0,55% Opción de venta
NOMURA HOLDINGS INC $6 273 000 425 000 0,52% Opción de compra
DIADEMA PARTNERS LP $5 904 000 400 000 0,49% Opción de compra
Swiss National Bank $5 319 504 360 400 0,44% Acciones
XTX Topco Ltd $5 300 168 359 090 0,44% Acciones
Ikarian Capital, LLC $5 235 372 354 700 0,44% Opción de venta
CITIGROUP INC $4 659 717 315 699 0,39% Acciones
RENAISSANCE TECHNOLOGIES LLC $4 580 973 310 364 0,38% Acciones
DAGCO, INC. $4 351 740 1 028 780 0,36% Acciones
Everhart Financial Group, Inc. $4 251 146 288 018 0,35% Acciones
Rafferty Asset Management, LLC $3 540 806 239 892 0,29% Acciones
RHUMBLINE ADVISERS $3 400 726 230 402 0,28% Acciones
Walleye Capital LLC $3 377 088 228 800 0,28% Opción de venta
GOLDMAN SACHS GROUP INC $3 125 991 211 788 0,26% Acciones
TUDOR INVESTMENT CORP ET AL $3 087 792 209 200 0,26% Opción de venta
WELLINGTON MANAGEMENT GROUP LLP $2 992 738 202 760 0,25% Acciones
BOOTHBAY FUND MANAGEMENT, LLC $2 982 996 202 100 0,25% Opción de venta
Jefferies Financial Group Inc. $2 958 775 200 459 0,25% Acciones
Jefferies Financial Group Inc. $2 953 476 200 100 0,25% Opción de venta
Mariner, LLC $2 925 609 198 212 0,24% Acciones
MILLENNIUM MANAGEMENT LLC $2 895 912 196 200 0,24% Opción de compra
Bank of New York Mellon Corp $2 801 212 189 784 0,23% Acciones
ALPS ADVISORS INC $2 776 459 188 107 0,23% Acciones
JANE STREET GROUP, LLC $2 405 880 163 000 0,20% Opción de venta
LPL Financial LLC $2 297 586 155 663 0,19% Acciones
SIMPLEX TRADING, LLC $2 274 501 154 099 0,19% Acciones
BlackRock, Inc. $2 222 708 150 590 0,19% Acciones
WELLS FARGO & COMPANY/MN $2 208 775 149 646 0,18% Acciones
Vontobel Holding Ltd. $2 166 207 146 762 0,18% Acciones
TUDOR INVESTMENT CORP ET AL $2 069 352 140 200 0,17% Opción de compra
Vanguard Global Advisers, LLC $1 918 874 130 005 0,16% Acciones
VANGUARD ASSET MANAGEMENT, Ltd $1 859 598 125 989 0,15% Acciones
Caption Management, LLC $1 845 000 125 000 0,15% Opción de venta
PROFUND ADVISORS LLC $1 780 159 120 607 0,15% Acciones
MetLife Investment Management, LLC $1 624 810 110 082 0,14% Acciones
Daiwa Securities Group Inc. $1 589 652 107 700 0,13% Opción de venta
Daiwa Securities Group Inc. $1 512 900 102 500 0,13% Acciones
DIADEMA PARTNERS LP $1 476 000 100 000 0,12% Opción de venta
HIGHBRIDGE CAPITAL MANAGEMENT LLC $1 467 144 99 400 0,12% Acciones
STATE OF WISCONSIN INVESTMENT BOARD $1 405 300 95 210 0,12% Acciones
Harvest Investment Services, LLC $1 394 554 94 482 0,12% Acciones
ORBIMED ADVISORS LLC $1 365 300 92 500 0,11% Opción de venta
Zurcher Kantonalbank (Zurich Cantonalbank) $1 229 582 83 305 0,10% Acciones
Invesco Ltd. $1 104 816 74 852 0,09% Acciones
Gotham Asset Management, LLC $1 097 317 74 344 0,09% Acciones
FULCRUM WEALTH ADVISORS, LLC $1 081 214 73 253 0,09% Acciones
ALLIANCEBERNSTEIN L.P. $998 534 236 060 0,08% Acciones
NEW YORK STATE COMMON RETIREMENT FUND $978 588 66 300 0,08% Acciones
Verition Fund Management LLC $916 596 62 100 0,08% Opción de venta
OSAIC HOLDINGS, INC. $889 776 60 284 0,07% Acciones
FIFTH THIRD BANCORP $888 404 60 190 0,07% Acciones
State of New Jersey Common Pension Fund D $857 069 58 067 0,07% Acciones
Verition Fund Management LLC $832 464 56 400 0,07% Opción de compra
Police & Firemen's Retirement System of New Jersey $821 630 55 666 0,07% Acciones
ARIZONA STATE RETIREMENT SYSTEM $731 388 49 552 0,06% Acciones
Caption Management, LLC $728 745 49 373 0,06% Acciones
MANUFACTURERS LIFE INSURANCE COMPANY, THE $722 310 48 937 0,06% Acciones
Russell Investments Group, Ltd. $704 494 47 730 0,06% Acciones
SIG BROKERAGE, LP $689 292 46 700 0,06% Opción de compra
Vanguard Investments Australia, Ltd. $684 643 46 385 0,06% Acciones
COMMONWEALTH EQUITY SERVICES, LLC $665 481 45 087 0,06% Acciones
INSTRUMENTAL WEALTH, LLC $662 931 44 914 0,06% Acciones
Persistent Asset Partners Ltd $655 647 758 0,05% Opción de compra
Virtus Investment Advisers, LLC $616 791 41 788 0,05% Acciones
Accurate Wealth Management, LLC $614 707 47 462 0,05% Acciones
AXXCESS WEALTH MANAGEMENT, LLC $610 665 41 373 0,05% Acciones
KLP KAPITALFORVALTNING AS $600 732 40 700 0,05% Acciones
SJS Investment Consulting Inc. $590 400 40 000 0,05% Acciones
Wealthfront Advisers LLC $587 773 39 822 0,05% Acciones
Quantinno Capital Management LP $546 651 37 036 0,05% Acciones
Visionary Horizons, LLC $531 360 36 000 0,04% Acciones
Kestra Advisory Services, LLC $516 305 34 980 0,04% Acciones
NORTHSTAR ASSET MANAGEMENT Co $509 400 45 000 0,04% Acciones

Informantes de la empresa 42 insiders · 17 directivos · 9 consejeros

Insider Rol Última actividad Acciones en propiedad Compras 12m Ventas 12m Neto 12m
Andelos M. Stergiou President and CEO 16 de junio de 2026 A 1 759 183 0 0 $0
Noah D Beerman CEO and President 15 de marzo de 2011 A 92 994 0 0 $0
John Thomas Burns CFO 7 de enero de 2026 A 554 327 0 0 $0
Gene Mack CFO and Treasurer 20 de abril de 2018 A 0 0 $0
Robert Eugene Kennedy Vice President and CFO 13 de abril de 2011 A 379 294 0 0 $0
Stephen J. Dipalma CFO, EVP, Secretary 15 de enero de 2009 A 0 0 $0
Dragan Cicic SVP, Chief Development Officer 7 de enero de 2026 A 557 805 0 0 $0
Robert Francomano Chief Commercial Officer 22 de enero de 2024 A 40 918 0 0 $0
Barbara A Wood EVP, Gen. Counsel, Corp. Sec. 22 de enero de 2024 A 117 225 0 0 $0
Nicholas J. Sarlis Chief Medical Officer and SVP 14 de marzo de 2019 A 0 0 $0
Gregory M Torre CRO and SVP 13 de marzo de 2018 A 0 0 $0
Amy B Tata Principlw Acctg Officer & Cont 15 de marzo de 2011 A 14 065 0 0 $0
Ramani Varanasi VP Business Development 15 de marzo de 2011 A 41 083 0 0 $0
Anastasia Khvorova Chief Science Officer 15 de marzo de 2011 A 60 559 0 0 $0
Pamela Pavco VP of Pharmaceutical Devlpmt 15 de marzo de 2011 A 44 940 0 0 $0
Konstantinos Andrikopoulos VP, Legal 15 de abril de 2010 A 5 750 0 0 $0
Dmitry Samarsky VP, Technology Development 31 de marzo de 2010 S 0 0 0 $0
Katherine Bach Kalin Consejero 7 de enero de 2026 A 154 400 1 0 $100 806
John Varian Consejero 7 de enero de 2026 A 72 900 0 0 $0
Jane Wasman Consejero 7 de enero de 2026 A 92 900 0 0 $0
David A Scheinberg Consejero 7 de enero de 2026 A 73 082 0 0 $0
Robert L Van Nostrand Consejero 7 de enero de 2026 A 82 900 0 0 $0
Stephen F Ghiglieri Consejero 14 de marzo de 2019 A 0 0 $0
Fabio Lopez Consejero 12 de junio de 2018 A 0 0 $0
Irving M. Einhorn 10 de octubre de 2017 A 34 690 0 0 $0
William Ashton 10 de octubre de 2017 A 38 154 0 0 $0
Richard Chin 10 de octubre de 2017 A 31 339 0 0 $0
Rudolph Nisi 10 de octubre de 2017 A 42 918 0 0 $0
Sanford Hillsberg 10 de octubre de 2017 A 56 950 0 0 $0
Mary Ann Gray 10 de octubre de 2017 A 39 167 0 0 $0
Stephen S Galliker 10 de octubre de 2017 A 36 039 0 0 $0
Thomas J Knapp 6 de febrero de 2017 A 0 0 $0
Bijan Nejadnik 17 de enero de 2017 A 0 0 $0
Ryan Dunlap 1 de junio de 2016 M 18 702 0 0 $0
Mark W. Schwartz 18 de diciembre de 2015 A 415 972 0 0 $0
Steven A Kriegsman 19 de junio de 2015 A 5 000 0 0 $0
Margaret Kivinski 16 de enero de 2015 A 0 0 $0
Brian L Hamilton 30 de junio de 2014 J 2 461 0 0 $0
Mark J Ahn 30 de junio de 2014 A 116 225 0 0 $0
Rosemary Mazanet 29 de enero de 2013 A 0 0 $0
CYTRX CORP 29 de diciembre de 2010 S 0 0 0 $0
Tod Woolf 15 de enero de 2009 A 0 0 $0

Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto

Activistas y propietarios del %+ 5 2 tenencias

Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.

Declarante Presentado Participación Estado Propósito Presentación
Equilibria Capital Management Limited (2), EQC Private Markets SAC Fund II Ltd — EQC Biotech Sely S Fund (2), EQC Private Markets SAC Fund Ltd — EQC Biotech Sely I Fund (2), EQC Private Markets SAC Fund Ltd — EQC Biotech Sely II Fund (2), EQC Private Markets II SAC Fund Ltd — EQC Biotech Sely III Fund (2), Varibobi Financial Holdings Ltd. (2), Daniel Tafur (2), Fabio López (2) ×4 presentaciones 10 de octubre de 2018 Presentación inicial SEC
Angelos M. Stergiou, M.D., Sc.D. h.c. 8 de enero de 2018 Presentación inicial M&A / venta SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Propiedad de ETFs Mantenido por 29 ETFs

El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.

Fondo Ponderación Unidades A fecha de Fuente
DWAS · Invesco Exchange-Traded Fund Trust … 0,77% 288 499 SH 8 de agosto de 2026 Diario
IWC · iShares Trust 0,50% 640 415 SH 8 de agosto de 2026 Diario
LABU · Direxion Shares ETF Trust 0,26% 268 465 NS 30 de abril de 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,23% 316 525 SH 8 de agosto de 2026 Diario
ICOP · iShares Trust 0,22% 126 361 SH 8 de agosto de 2026 Diario
CANC · Tema ETF Trust 0,22% 40 702 NS 31 de mayo de 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0,16% 202 339 SH 8 de agosto de 2026 Diario
IWO · iShares Trust 0,14% 1 712 069 SH 8 de agosto de 2026 Diario
VTWO · VANGUARD SCOTTSDALE FUNDS 0,08% 1 086 285 SH 8 de agosto de 2026 Diario
IWM · iShares Trust 0,07% 4 828 431 SH 8 de agosto de 2026 Diario
ISCG · iShares Trust 0,07% 57 511 SH 8 de agosto de 2026 Diario
GSSC · Goldman Sachs ETF Trust 0,05% 51 293 NS 31 de mayo de 2026 N-PORT
PICK · iShares, Inc. 0,04% 122 564 SH 8 de agosto de 2026 Diario
ITWO · ProShares Trust 0,04% 8 088 NS 31 de mayo de 2026 N-PORT
VHT · VANGUARD WORLD FUND 0,04% 540 244 SH 8 de agosto de 2026 Diario
ISCF · iShares Trust 0,04% 30 200 SH 8 de agosto de 2026 Diario
ISCB · iShares Trust 0,03% 8 283 SH 8 de agosto de 2026 Diario
VXF · VANGUARD INDEX FUNDS 0,03% 2 134 285 SH 8 de agosto de 2026 Diario
WSML · iShares Trust 0,03% 16 889 SH 8 de agosto de 2026 Diario
RSSL · Global X Funds 0,03% 74 459 NS 30 de abril de 2026 N-PORT
UWM · ProShares Trust 0,02% 6 326 NS 31 de mayo de 2026 N-PORT
URTY · ProShares Trust 0,02% 6 397 NS 31 de mayo de 2026 N-PORT
HDG · ProShares Trust 0,01% 161 NS 31 de mayo de 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0,01% 64 480 NS 31 de mayo de 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,00% 3 554 NS 31 de mayo de 2026 N-PORT
ITOT · iShares Trust 0,00% 273 812 SH 8 de agosto de 2026 Diario
IWV · iShares Trust 0,00% 43 929 SH 8 de agosto de 2026 Diario
VTI · VANGUARD INDEX FUNDS 0,00% 5 908 560 SH 8 de agosto de 2026 Diario
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 15 706 SH 8 de agosto de 2026 Diario