STOK Stoke Therapeutics, Inc. - Common Stock
STOK Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
STOK Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
STOK Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 8 42,1%
- Compra 10 52,6%
- Mantener 1 5,3%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
12 analistas · 2026-08-22Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.93 | $-0.81 | -0.12% |
| 31 de marzo de 2026 | $-0.79 | $-0.84 | 0.05% |
| 31 de diciembre de 2025 | $-0.97 | $-0.73 | -0.24% |
| 30 de septiembre de 2025 | $-0.65 | $-0.58 | -0.07% |
| 30 de junio de 2025 | $-0.40 | $-0.52 | 0.12% |
| 31 de marzo de 2025 | $1.98 | $-0.43 | 2.4% |
| 31 de diciembre de 2024 | $-0.18 | $-0.54 | 0.36% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| STOK | $1.87B | -264.5 | 404.5% | -3.7% | -2.0% | — |
| PURR | — | — | — | — | — | — |
| GENB | — | — | — | — | — | — |
| VRDN | $3.17B | -7.7 | 23359.9% | -483.6% | -55.4% | — |
| BHVN | $1.50B | -1.6 | — | — | -310.8% | — |
| ZBIO | $1.98B | -4.3 | 100.0% | -3777.4% | -156.8% | — |
| PVLA | $1.30B | -28.2 | 65.3% | -1610.6% | -110.1% | — |
| AGIO | $1.59B | -3.8 | 48.0% | -764.0% | -32.2% | — |
| TSHA | $1.57B | -16.2 | 17.3% | -1115.3% | -44.0% | — |
| SRPT | $2.26B | -3.0 | 15.6% | -32.5% | -57.1% | — |
| DMRA | — | — | 38.3% | -17981.1% | -167.0% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 15
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $184M | $37M | $9M | $12M | |
| R&D Expense | $138M | $89M | $82M | $78M | |
| SG&A Expense | $67M | $49M | $41M | $39M | |
| Operating Expenses | $205M | $138M | $124M | $117M | |
| Operating Income | $-21M | $-101M | $-115M | $-104M | |
| Interest Expense | $9.0K | $26.0K | $49.0K | · | |
| Interest Income | $14M | $13M | $10M | · | |
| Other Non-op | $-51.0K | $-247.0K | $166.0K | $167.0K | |
| Income Tax | $0 | · | · | · | |
| Net Income | $-7M | $-89M | $-105M | $-101M | |
| EPS (Basic) | $-0.12 | $-1.65 | $-2.38 | $-2.60 | |
| EPS (Diluted) | $-0.12 | $-1.65 | $-2.38 | $-2.60 | |
| Shares (Basic) | 59,219,184 | 54,008,883 | 43,994,862 | 38,897,442 | |
| Shares (Diluted) | 59,219,184 | 54,008,883 | 43,994,862 | 38,897,442 | |
| EBITDA | $-21M | $-101M | $-115M | $-104M |
Balance general 21
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $84M | $128M | $191M | $114M | |
| Receivables | $6M | $2M | · | · | |
| Prepaid Expense | $9M | $11M | $11M | $11M | |
| Other Current Assets | $4M | $2M | $3M | $3M | |
| Current Assets | $306M | $233M | $215M | $244M | |
| PP&E (Net) | $3M | $4M | $6M | $7M | |
| PP&E (Gross) | $13M | $13M | $12M | $11M | |
| Accum. Depreciation | $10M | $9M | $7M | $4M | |
| Total Assets | $418M | $272M | $228M | $256M | |
| Accounts Payable | $5M | $2M | $2M | $766.0K | |
| Current Liabilities | $58M | $40M | $31M | $31M | |
| Capital Leases | $1M | $2M | $5M | $3M | |
| Other Non-current Liabilities | $1M | $2M | $5M | $3M | |
| Total Liabilities | $66M | $43M | $69M | $71M | |
| Common Stock | $5.0K | $5.0K | $5.0K | $4.0K | |
| Paid-in Capital | $850M | $720M | $561M | $483M | |
| Retained Earnings | $-498M | $-491M | $-402M | $-297M | |
| AOCI | $543.0K | $-151.0K | $-24.0K | $-1M | |
| Stockholders' Equity | $352M | $229M | $160M | $185M | |
| Liabilities + Equity | $418M | $272M | $228M | $256M | |
| Shares Outstanding | 58,921,999 | 54,032,826 | 45,918,233 | 39,439,575 |
Flujo de Efectivo 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $32M | $27M | $25M | $23M | |
| Operating Cash Flow | $46M | $-87M | $-81M | $-32M | |
| CapEx | $670.0K | $203.0K | $2M | $4M | |
| Investing Cash Flow | $-187M | $-107M | $106M | $-46M | |
| Financing Cash Flow | $97M | $131M | $53M | $46M | |
| Net Change in Cash | $-44M | $-63M | $78M | $-31M | |
| Taxes Paid | $573.0K | · | · | · | |
| Free Cash Flow | $45M | $-87M | $-83M | $-36M |
Rentabilidad 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | -11.2% | -277.3% | -1307.2% | -841.2% | |
| Net Margin | -3.7% | -243.4% | -1192.5% | -814.7% | |
| EBITDA Margin | -11.2% | -277.3% | -1307.2% | -841.2% | |
| ROA | -2.0% | -35.6% | -43.2% | -40.8% | |
| ROE | -2.0% | -38.6% | -63.0% | -52.0% |
Liquidez y Solvencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 5.3 | 5.8 | 7.0 | 7.8 | |
| Quick Ratio | 1.6 | 3.2 | 6.2 | 3.6 | |
| Interest Coverage | -2287.8 | -3898.9 | · | · |
Eficiencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.5 | 0.1 | 0.0 | 0.1 | |
| Receivables Turnover | 48.5 | · | · | · |
Tasas de Crecimiento 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue YoY | 404.5% | 316.3% | -29.2% | · | |
| Revenue CAGR 3Y | 145.9% | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $184M | $37M | $9M | $12M | |
| Net Income TTM | $-7M | $-89M | $-105M | $-101M | |
| Market Cap | $1.87B | $596M | $242M | $364M | |
| P/E | -264.5 | -6.7 | -2.2 | -3.5 | |
| P/S | 10.1 | 16.3 | 27.5 | 29.3 | |
| P/B | 5.3 | 2.6 | 1.5 | 2.0 | |
| P / Tangible Book | 5.3 | 2.6 | 1.5 | 2.0 | |
| P / Cash Flow | 41.0 | -6.9 | -3.0 | -11.4 | |
| P / FCF | 41.6 | -6.8 | -2.9 | -10.2 | |
| Earnings Yield | -0.38% | -15.0% | -45.2% | -28.2% |
Estado de resultados 16
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $9M | $6M | $1M | $11M | $14M | $159M | $23M | $5M | $5M | $4M | $3M | $3M | $-2M | $5M | $3M | $3M | |
| R&D Expense | $50M | $40M | $42M | $38M | $26M | $33M | $23M | $22M | $21M | $22M | $22M | $20M | $21M | $20M | $21M | $20M | |
| SG&A Expense | $25M | $20M | $21M | $16M | $15M | $15M | $13M | $13M | $13M | $10M | $11M | $10M | $10M | $10M | $9M | $10M | |
| Operating Expenses | $75M | $60M | $63M | $54M | $41M | $47M | $36M | $35M | $34M | $33M | $32M | $31M | $31M | $30M | $30M | $30M | |
| Operating Income | $-65M | $-53M | $-61M | $-43M | $-27M | $111M | $-14M | $-30M | $-29M | $-28M | $-30M | $-27M | $-33M | $-25M | $-27M | $-27M | |
| Interest Expense | $17.0K | $23.0K | $2.0K | $3.0K | $3.0K | $1.0K | $-1.0K | $0 | $5.0K | $22.0K | · | · | · | · | · | · | |
| Interest Income | $4M | $3M | $4M | $3M | $4M | $3M | $3M | $4M | $4M | $2M | · | · | · | · | · | · | |
| Other Non-op | $308.0K | $18.0K | $-110.0K | $3.0K | $28.0K | $28.0K | $201.0K | $28.0K | $-48.0K | $-428.0K | $42.0K | $41.0K | $41.0K | $42.0K | $41.0K | $42.0K | |
| Pretax Income | $-62M | $-50M | · | $-40M | $-23M | $114M | · | $-26M | $-26M | $-26M | · | · | · | · | · | · | |
| Income Tax | $0 | $0 | $0 | $-1M | $0 | $1M | · | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | |
| Net Income | $-62M | $-50M | $-58M | $-38M | $-23M | $113M | $-10M | $-26M | $-26M | $-26M | $-27M | $-25M | $-31M | $-23M | $-26M | $-26M | |
| EPS (Basic) | $-0.93 | $-0.79 | $-1.02 | $-0.65 | $-0.40 | $1.95 | $-0.15 | $-0.47 | $-0.46 | $-0.57 | $-0.61 | $-0.55 | $-0.69 | $-0.53 | $-0.65 | $-0.66 | |
| EPS (Diluted) | $-0.93 | $-0.79 | $-0.97 | $-0.65 | $-0.40 | $1.90 | $-0.15 | $-0.47 | $-0.46 | $-0.57 | $-0.61 | $-0.55 | $-0.69 | $-0.53 | $-0.65 | $-0.66 | |
| Shares (Basic) | 66,017,895 | 63,063,507 | -115,609,022 | 58,611,677 | 58,353,855 | 57,862,674 | -104,345,028 | 56,341,074 | 55,765,948 | 46,246,889 | -86,996,093 | 44,266,017 | 44,188,464 | 42,536,474 | -77,229,527 | 39,420,310 | |
| Shares (Diluted) | 66,017,895 | 63,063,507 | -117,144,948 | 58,611,677 | 58,353,855 | 59,398,600 | -104,345,028 | 56,341,074 | 55,765,948 | 46,246,889 | -86,996,093 | 44,266,017 | 44,188,464 | 42,536,474 | -77,229,527 | 39,420,310 | |
| EBITDA | $-65M | $-53M | · | $-43M | $-27M | $111M | · | $-30M | $-29M | $-28M | · | $-27M | $-33M | $-25M | · | $-27M |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $110M | $156M | $84M | $83M | $101M | $275M | $128M | $150M | $193M | $179M | $191M | $190M | $192M | $190M | $114M | $113M | |
| Receivables | $7M | $4M | $6M | $9M | · | · | $2M | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $15M | $10M | $9M | $8M | $14M | $13M | $11M | $10M | $10M | $11M | $11M | $11M | $11M | $10M | $11M | $13M | |
| Other Current Assets | $6M | $7M | $4M | $6M | $7M | $5M | $2M | $4M | $4M | $4M | $3M | $4M | $4M | $6M | $3M | · | |
| Current Assets | $323M | $367M | $306M | $272M | $270M | $376M | $233M | $254M | $297M | $193M | $215M | $230M | $246M | $270M | $244M | $265M | |
| PP&E (Net) | $5M | $3M | $3M | $3M | $3M | $4M | $4M | $4M | $5M | $5M | $6M | $6M | $6M | $7M | $7M | $7M | |
| PP&E (Gross) | · | · | $13M | · | · | · | $13M | · | · | · | $12M | · | · | · | $11M | · | |
| Accum. Depreciation | · | · | $10M | · | · | · | $9M | · | · | · | $7M | · | · | · | $4M | · | |
| Total Assets | $394M | $443M | $418M | $360M | $385M | $407M | $272M | $293M | $308M | $205M | $228M | $240M | $257M | $282M | $256M | $278M | |
| Accounts Payable | $5M | $7M | $5M | $6M | $4M | $2M | $2M | $2M | $4M | $2M | $2M | $3M | $2M | $4M | $766.0K | $2M | |
| Current Liabilities | $42M | $41M | $58M | $42M | $39M | $45M | $40M | $50M | $44M | $36M | $31M | $25M | $22M | $32M | $31M | $29M | |
| Capital Leases | $837.0K | $990.0K | $1M | $2M | $1M | $2M | $2M | $3M | $4M | $4M | $5M | $819.0K | $1M | $2M | $3M | $3M | |
| Other Non-current Liabilities | $837.0K | $991.0K | $1M | $2M | $1M | $2M | $2M | $3M | $4M | $4M | $5M | $959.0K | $2M | $2M | $3M | $4M | |
| Total Liabilities | $48M | $48M | $66M | $52M | $50M | $57M | $43M | $61M | $65M | $65M | $69M | $67M | $67M | $68M | $71M | $73M | |
| Common Stock | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Paid-in Capital | $955M | $943M | $850M | $747M | $736M | $728M | $720M | $712M | $697M | $569M | $561M | $548M | $541M | $534M | $483M | $477M | |
| Retained Earnings | $-609M | $-548M | $-498M | $-440M | $-401M | $-378M | $-491M | $-480M | $-454M | $-428M | $-402M | $-375M | $-350M | $-320M | $-297M | $-271M | |
| AOCI | $-542.0K | $-115.0K | $543.0K | $446.0K | $96.0K | $-104.0K | $-151.0K | $166.0K | $-15.0K | · | $-24.0K | $-147.0K | $-379.0K | $-598.0K | $-1M | $-2M | |
| Stockholders' Equity | $346M | $395M | $352M | $308M | $335M | $350M | $229M | $232M | $243M | $140M | $160M | $173M | $190M | $214M | $185M | $204M | |
| Liabilities + Equity | $394M | $443M | $418M | $360M | $385M | $407M | $272M | $293M | $308M | $205M | $228M | $240M | $257M | $282M | $256M | $278M | |
| Shares Outstanding | 62,402,595 | 62,240,347 | 58,921,999 | 55,120,002 | 54,723,455 | 54,595,714 | 54,032,826 | 52,941,191 | 52,305,641 | 46,498,077 | 45,918,233 | 44,293,115 | 44,202,997 | 44,175,089 | 39,439,575 | 39,426,440 |
Flujo de Efectivo 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $11M | $9M | $10M | $8M | $8M | $7M | $7M | $7M | $7M | $5M | $6M | $7M | $7M | $6M | $6M | $6M | |
| Operating Cash Flow | $-57M | $-61M | $-30M | $-30M | $-25M | $132M | $-23M | $-22M | $-17M | $-25M | $-21M | $-17M | $-22M | $-21M | $-22M | $-22M | |
| CapEx | $2M | $353.0K | $232.0K | $132.0K | $154.0K | $152.0K | $42.0K | $103.0K | $46.0K | $12.0K | $229.0K | $383.0K | $839.0K | $165.0K | $409.0K | $2M | |
| Investing Cash Flow | $9M | $51M | $-61M | $9M | $-148M | $14M | $819.0K | $-30M | $-88M | $10M | $15M | $15M | $23M | $53M | $22M | $67M | |
| Financing Cash Flow | $2M | $84M | $92M | $3M | $554.0K | $1M | $568.0K | $8M | $121M | $2M | $7M | $562.0K | $48.0K | $45M | $43.0K | $434.0K | |
| Net Change in Cash | $-46M | $74M | $826.0K | $-18M | $-173M | $147M | $-22M | $-43M | $15M | $-13M | $1M | $-2M | $2M | $77M | $160.0K | $46M | |
| Free Cash Flow | · | $-61M | · | · | · | $132M | · | · | · | $-25M | · | · | · | $-22M | · | · | |
| Levered FCF | · | $-61M | · | · | · | $132M | · | · | · | · | · | · | · | · | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -701.6% | -857.6% | · | -405.3% | -197.6% | 70.2% | · | -613.1% | -607.4% | -673.0% | · | -823.3% | 1340.7% | -479.2% | · | -934.5% | |
| Net Margin | -660.8% | -802.8% | · | -360.7% | -170.0% | 71.2% | · | -540.0% | -531.9% | -625.6% | · | -741.9% | 1235.5% | -437.6% | · | -898.8% | |
| Pretax Margin | -660.8% | -802.8% | · | -372.7% | -170.0% | 72.0% | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -701.6% | -857.6% | · | -405.3% | -197.6% | 70.2% | · | -613.1% | -607.4% | -673.0% | · | -823.3% | 1340.7% | -479.2% | · | -934.5% | |
| ROA | -15.8% | -11.8% | · | -11.7% | -6.8% | 36.9% | · | -9.9% | -9.1% | -10.8% | · | -9.5% | -11.0% | -7.5% | · | -9.8% | |
| ROE | -18.1% | -13.4% | · | -14.2% | -8.1% | 46.0% | · | -13.1% | -11.9% | -14.9% | · | -13.0% | -14.8% | -9.9% | · | -11.8% | |
| ROIC | -18.9% | -13.5% | · | -13.5% | -8.2% | 31.4% | · | · | · | · | · | · | · | · | · | · |
Liquidez y Solvencia 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.7 | 9.0 | · | 6.5 | 7.0 | 8.4 | · | 5.1 | 6.7 | 5.4 | · | 9.1 | 11.3 | 8.6 | · | 9.2 | |
| Quick Ratio | 2.8 | 3.9 | · | 2.2 | 2.6 | 6.2 | · | 3.0 | 4.3 | 5.0 | · | 7.5 | 8.8 | 6.0 | · | 3.9 | |
| Interest Coverage | -3848.8 | -2322.5 | · | -14363.7 | -9100.0 | 111240.0 | · | · | · | · | · | · | · | · | · | · |
Eficiencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.5 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | -0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | 2.6 | 2.8 | · | 2.3 | · | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $40M | $189M | · | $188M | $182M | $173M | · | $17M | $10M | $10M | · | $9M | $9M | $14M | · | · | |
| Net Income TTM | $-173M | $1M | · | $25M | $37M | $34M | · | $-103M | $-107M | $-104M | · | $-104M | $-104M | $-98M | · | $-98M | |
| Market Cap | $2.04B | $2.03B | · | $1.30B | $621M | $363M | · | $651M | $707M | $628M | · | $175M | $470M | $368M | · | $506M | |
| P/E | -11.8 | 542.7 | · | 61.8 | 19.9 | 16.6 | · | -6.0 | -6.0 | -5.8 | · | -1.6 | -4.2 | -3.4 | · | -5.0 | |
| P/S | 51.0 | 10.7 | · | 6.9 | 3.4 | 2.1 | · | 37.7 | 71.6 | 61.6 | · | 19.6 | 53.4 | 25.8 | · | · | |
| P/B | 5.9 | 5.1 | · | 4.2 | 1.9 | 1.0 | · | 2.8 | 2.9 | 4.5 | · | 1.0 | 2.5 | 1.7 | · | 2.5 | |
| P / Tangible Book | 5.9 | 5.1 | · | 4.2 | 1.9 | 1.0 | · | 2.8 | 2.9 | 4.5 | · | 1.0 | 2.5 | 1.7 | · | 2.5 | |
| P / Cash Flow | · | -33.5 | · | · | · | 2.8 | · | · | · | -25.6 | · | · | · | -17.2 | · | · | |
| P / FCF | · | -33.3 | · | · | · | 2.8 | · | · | · | -25.5 | · | · | · | -17.1 | · | · | |
| Earnings Yield | -8.5% | 0.18% | · | 1.6% | 5.0% | 6.0% | · | -16.7% | -16.8% | -17.3% | · | -61.7% | -23.6% | -29.8% | · | -19.9% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $184M | $37M | $9M | $12M | — |
| Margen Operativo % | -11.2% | -277.3% | -1307.2% | -841.2% | — |
| Beneficio neto | $-7M | $-89M | $-105M | $-101M | $-86M |
| EPS Diluido | $-0.12 | $-1.65 | $-2.38 | $-2.60 | $-2.34 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 5.3 | 5.8 | 7.0 | 7.8 | 13.4 |
| Ratio Rápido | 1.6 | 3.2 | 6.2 | 3.6 | 8.5 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $45M | $-87M | $-83M | $-36M | $-68M |
Últimas noticias Noticias recientes que mencionan a esta empresa
Señales de trading Señales recientes de compra/venta con precio de entrada y ratio riesgo/recompensa
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Propietarios institucionales (13F) 205 declarantes · $2.0B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 30 (-15 vs trimestre anterior) | 25 (-1 vs trimestre anterior) | 67 (-5 vs trimestre anterior) | 57 (-1 vs trimestre anterior) | +3.9M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| RTW INVESTMENTS, LP | $184 001 738 | 5 623 525 | 9,14% | Acciones |
| FMR LLC | $150 968 444 | 4 613 950 | 7,50% | Acciones |
| Lynx1 Capital Management LP | $132 136 579 | 4 038 404 | 6,56% | Acciones |
| Redmile Group, LLC | $129 110 502 | 3 945 920 | 6,41% | Acciones |
| BAKER BROS. ADVISORS LP | $109 176 726 | 3 336 697 | 5,42% | Acciones |
| TORONTO DOMINION BANK | $103 829 002 | 3 173 258 | 5,16% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $97 499 612 | 2 979 817 | 4,84% | Acciones |
| STATE STREET CORP | $93 325 293 | 2 852 240 | 4,63% | Acciones |
| VANGUARD GROUP INC | $86 966 267 | 2 739 958 | 4,32% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $84 644 579 | 2 586 937 | 4,20% | Acciones |
| BVF INC/IL | $83 356 065 | 2 547 557 | 4,14% | Acciones |
| Siren, L.L.C. | $65 287 754 | 1 995 347 | 3,24% | Acciones |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $59 664 920 | 1 823 500 | 2,96% | Acciones |
| Skorpios Trust | $53 020 254 | 2 256 181 | 2,63% | Acciones |
| JANUS HENDERSON GROUP PLC | $51 840 980 | 1 593 881 | 2,57% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $43 134 838 | 1 318 037 | 2,14% | Acciones |
| Assenagon Asset Management S.A. | $36 920 855 | 1 128 388 | 1,83% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $31 236 868 | 954 672 | 1,55% | Acciones |
| Polar Capital Holdings Plc | $27 279 188 | 833 716 | 1,35% | Acciones |
| EcoR1 Capital, LLC | $24 049 200 | 735 000 | 1,19% | Acciones |
| MPM BIOIMPACT LLC | $23 666 834 | 723 314 | 1,18% | Acciones |
| Opaleye Management Inc. | $22 904 000 | 700 000 | 1,14% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $18 552 011 | 566 993 | 0,92% | Acciones |
| Troluce Capital Advisors LLC | $16 242 732 | 496 416 | 0,81% | Acciones |
| FIRST TRUST ADVISORS LP | $16 062 673 | 490 913 | 0,80% | Acciones |
| Candriam S.C.A. | $15 694 935 | 480 136 | 0,78% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $15 280 633 | 467 012 | 0,76% | Acciones |
| Granahan Investment Management, LLC | $15 103 814 | 461 608 | 0,75% | Acciones |
| Erste Asset Management GmbH | $13 875 261 | 428 381 | 0,69% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $13 169 898 | 402 503 | 0,65% | Acciones |
| GOLDMAN SACHS GROUP INC | $12 775 295 | 390 443 | 0,63% | Acciones |
| Parkman Healthcare Partners LLC | $11 630 095 | 355 443 | 0,58% | Acciones |
| Artisan Partners Limited Partnership | $11 620 606 | 355 153 | 0,58% | Acciones |
| TANG CAPITAL MANAGEMENT LLC | $9 816 000 | 300 000 | 0,49% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $8 540 836 | 261 028 | 0,42% | Acciones |
| CITADEL ADVISORS LLC | $7 719 237 | 235 918 | 0,38% | Acciones |
| Birchview Capital, LP | $5 827 759 | 178 110 | 0,29% | Acciones |
| NORGES BANK | $5 339 904 | 163 200 | 0,27% | Acciones |
| BAILLIE GIFFORD & CO | $4 441 216 | 135 734 | 0,22% | Acciones |
| DAFNA Capital Management LLC | $4 282 230 | 130 875 | 0,21% | Acciones |
| ExodusPoint Capital Management, LP | $4 242 475 | 129 660 | 0,21% | Acciones |
| BANK OF AMERICA CORP /DE/ | $4 226 737 | 129 179 | 0,21% | Acciones |
| JANE STREET GROUP, LLC | $3 932 879 | 120 198 | 0,20% | Acciones |
| GILDER GAGNON HOWE & CO LLC | $3 699 487 | 113 065 | 0,18% | Acciones |
| BlackRock, Inc. | $3 657 180 | 111 772 | 0,18% | Acciones |
| Jump Financial, LLC | $3 414 332 | 104 350 | 0,17% | Acciones |
| Schonfeld Strategic Advisors LLC | $3 344 932 | 102 229 | 0,17% | Acciones |
| JPMORGAN CHASE & CO | $2 800 925 | 83 993 | 0,14% | Acciones |
| Palo Alto Investors LP | $2 769 126 | 84 631 | 0,14% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $2 649 273 | 80 968 | 0,13% | Acciones |
| XTX Topco Ltd | $2 604 937 | 79 613 | 0,13% | Acciones |
| RHUMBLINE ADVISERS | $2 484 451 | 75 931 | 0,12% | Acciones |
| Swiss National Bank | $2 427 824 | 74 200 | 0,12% | Acciones |
| Trexquant Investment LP | $2 404 102 | 73 475 | 0,12% | Acciones |
| TD Asset Management Inc | $2 198 784 | 67 200 | 0,11% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2 164 755 | 66 160 | 0,11% | Acciones |
| CITIGROUP INC | $2 164 330 | 66 147 | 0,11% | Acciones |
| Rhenman & Partners Asset Management AB | $2 110 440 | 64 500 | 0,10% | Acciones |
| ALPS ADVISORS INC | $2 061 687 | 63 010 | 0,10% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $2 040 779 | 62 371 | 0,10% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $2 031 418 | 62 390 | 0,10% | Acciones |
| HighVista Strategies LLC | $2 006 260 | 61 316 | 0,10% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 968 664 | 60 167 | 0,10% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $1 925 343 | 58 843 | 0,10% | Acciones |
| Bank of New York Mellon Corp | $1 903 453 | 58 174 | 0,09% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 680 291 | 51 606 | 0,08% | Acciones |
| Woodline Partners LP | $1 639 926 | 50 120 | 0,08% | Acciones |
| Quantinno Capital Management LP | $1 633 644 | 49 928 | 0,08% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $1 623 272 | 49 611 | 0,08% | Acciones |
| Moran Wealth Management, LLC | $1 569 807 | 47 977 | 0,08% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $1 469 128 | 44 900 | 0,07% | Acciones |
| Rafferty Asset Management, LLC | $1 431 238 | 43 742 | 0,07% | Acciones |
| HUSSMAN STRATEGIC ADVISORS, INC. | $1 374 240 | 42 000 | 0,07% | Acciones |
| Quadrature Capital Ltd | $1 348 882 | 41 225 | 0,07% | Acciones |
| PLATINUM INVESTMENT MANAGEMENT LTD | $1 335 467 | 40 815 | 0,07% | Acciones |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1 164 766 | 35 598 | 0,06% | Acciones |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1 093 033 | 33 746 | 0,05% | Acciones |
| MetLife Investment Management, LLC | $1 051 359 | 32 132 | 0,05% | Acciones |
| Corient Private Wealth LP | $1 009 020 | 30 838 | 0,05% | Acciones |
| OMERS ADMINISTRATION Corp | $981 600 | 30 000 | 0,05% | Acciones |
| Squarepoint Ops LLC | $959 023 | 29 310 | 0,05% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $883 833 | 27 012 | 0,04% | Acciones |
| Vanguard Global Advisers, LLC | $871 628 | 26 639 | 0,04% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $821 730 | 25 114 | 0,04% | Acciones |
| Cresset Asset Management, LLC | $798 728 | 24 411 | 0,04% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $736 200 | 22 500 | 0,04% | Opción de compra |
| PROFUND ADVISORS LLC | $733 452 | 22 416 | 0,04% | Acciones |
| Invesco Ltd. | $719 415 | 21 987 | 0,04% | Acciones |
| D. E. Shaw & Co., Inc. | $698 736 | 21 355 | 0,03% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $687 120 | 21 000 | 0,03% | Opción de venta |
| LPL Financial LLC | $675 504 | 20 645 | 0,03% | Acciones |
| AMERIPRISE FINANCIAL INC | $668 240 | 20 423 | 0,03% | Acciones |
| Balyasny Asset Management L.P. | $652 404 | 19 939 | 0,03% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $558 432 | 17 067 | 0,03% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $531 536 | 16 245 | 0,03% | Acciones |
| Aquatic Capital Management LLC | $506 211 | 15 471 | 0,03% | Acciones |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $498 587 | 15 238 | 0,02% | Acciones |
| AlphaQuest LLC | $477 243 | 15 036 | 0,02% | Acciones |
| MORGAN STANLEY | $476 959 | 14 577 | 0,02% | Acciones |
| CIM, LLC | $476 272 | 14 556 | 0,02% | Acciones |
Informantes de la empresa 17 insiders · 8 directivos · 9 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Ian F Smith | Chief Executive Officer | 17 de febrero de 2026 A | — | 0 | 0 | $0 |
| Thomas Leggett | Chief Financial Officer | 20 de marzo de 2025 A | — | 0 | 0 | $0 |
| Stephen J Tulipano | Former CFO | 27 de marzo de 2024 A | 20 746 | 0 | 0 | $0 |
| Jonathan Allan | GENERAL COUNSEL & CORP SEC | 14 de agosto de 2026 M | 21 225 | 0 | 6 | $-580 157 |
| Barry Ticho | CHIEF MEDICAL OFFICER | 14 de agosto de 2026 M | 25 655 | 0 | 8 | $-761 381 |
| Thomas Mccauley | Chief Scientific Officer | 15 de julio de 2026 A | — | 0 | 0 | $0 |
| Huw M. Nash | Chief Business Officer | 2 de julio de 2024 S | 0 | 0 | 0 | $0 |
| Gene Liau | EVP Research & Preclinical Dev | 2 de marzo de 2021 M | 21 351 | 0 | 0 | $0 |
| Edward M. Kaye MD | Consejero | 14 de agosto de 2026 M | 124 557 | 0 | 5 | $-1 648 321 |
| Seth Loring Harrison | Consejero | 16 de julio de 2026 G | 17 161 713 | 0 | 0 | $0 |
| Adrian R. Krainer | Consejero | 3 de junio de 2026 A | — | 0 | 0 | $0 |
| Jennifer Burstein | Consejero | 3 de junio de 2026 A | — | 0 | 0 | $0 |
| Arthur Tzianabos | Consejero | 3 de junio de 2026 A | — | 0 | 0 | $0 |
| Julie Smith | Consejero | 3 de junio de 2026 A | — | 0 | 0 | $0 |
| LEVIN ARTHUR A | Consejero | 3 de junio de 2026 A | 4 237 | 0 | 1 | $-22 264 |
| Garry E Menzel | Consejero | 3 de junio de 2025 A | — | 0 | 0 | $0 |
| Robin A. Walker | — | 7 de julio de 2020 S | 0 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 4 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Blue Horizon Enterprise Ltd, Ezbon International Ltd, Montrago Trustees Ltd, Skorpios Trust ×3 presentaciones | 26 de agosto de 2025 | 4,10% | Enmienda | — | SEC |
| Blue Horizon Enterprise Ltd., Ezbon International Limited, Montrago Trustees Limited, Skorpios Trust ×4 presentaciones | 27 de diciembre de 2024 | 13,00% | Enmienda | — | SEC |
| ATP Life Science Ventures, L.P., formerly known as Apple Tree Partners IV, L.P., ATP III GP, Ltd., Seth L. Harrison | 29 de junio de 2021 | — | Presentación inicial | — | SEC |
| Apple Tree Partners IV, L.P., ATP III GP, Ltd., Seth L. Harrison ×2 presentaciones | 27 de noviembre de 2020 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 53 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| FDM · First Trust Exchange-Traded Fund | 2,29% | 186 035 NS | 30 de junio de 2026 | N-PORT |
| GNOM · Global X Funds | 1,45% | 26 232 NS | 31 de mayo de 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 1,18% | 15 670 NS | 31 de mayo de 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 1,12% | 58 873 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,75% | 8 521 NS | 30 de abril de 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,60% | 10 049 NS | 31 de mayo de 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0,56% | 179 037 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,41% | 64 471 NS | 30 de abril de 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,26% | 100 854 NS | 30 de abril de 2026 | N-PORT |
| FYX · First Trust Exchange-Traded AlphaDE… | 0,23% | 85 288 NS | 30 de abril de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,13% | 3 654 SH | 21 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,12% | 75 065 SH | 19 de agosto de 2026 | Diario |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,11% | 16 704 NS | 30 de abril de 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,11% | 59 041 SH | 19 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,11% | 368 262 SH | 21 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,11% | 508 416 SH | 21 de agosto de 2026 | Diario |
| FSMD · FIDELITY COVINGTON TRUST | 0,10% | 72 925 NS | 30 de abril de 2026 | N-PORT |
| PSC · Principal Exchange-Traded Funds | 0,09% | 64 927 NS | 30 de junio de 2026 | N-PORT |
| BIB · ProShares Trust | 0,09% | 2 111 NS | 31 de mayo de 2026 | N-PORT |
| ESSC · Strategy Shares | 0,08% | 623 NS | 30 de abril de 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,07% | 6 327 SH | 21 de agosto de 2026 | Diario |
| GSSC · Goldman Sachs ETF Trust | 0,07% | 22 102 NS | 31 de mayo de 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,06% | 13 588 NS | 30 de abril de 2026 | N-PORT |
| IWM · iShares Trust | 0,05% | 1 391 940 SH | 21 de agosto de 2026 | Diario |
| ISCG · iShares Trust | 0,05% | 16 624 SH | 21 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,05% | 317 008 SH | 19 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,05% | 21 239 NS | 30 de abril de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,04% | 179 692 NS | 30 de abril de 2026 | N-PORT |
| RB · ProShares Trust | 0,04% | 15 NS | 31 de mayo de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,04% | 2 305 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,03% | 247 558 NS | 31 de mayo de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 27 657 SH | 21 de agosto de 2026 | Diario |
| ISCB · iShares Trust | 0,03% | 2 364 SH | 21 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,02% | 1 803 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,02% | 18 412 NS | 30 de abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,02% | 643 361 SH | 19 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,02% | 111 259 SH | 19 de agosto de 2026 | Diario |
| URTY · ProShares Trust | 0,02% | 1 824 NS | 31 de mayo de 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 2 915 SH | 21 de agosto de 2026 | Diario |
| DFAC · Dimensional ETF Trust | 0,01% | 127 867 NS | 30 de abril de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 1 903 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 46 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 4 751 NS | 30 de abril de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 16 308 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 10 507 NS | 30 de abril de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 80 377 SH | 21 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 13 611 SH | 21 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 28 492 NS | 31 de mayo de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 11 068 NS | 30 de abril de 2026 | N-PORT |
| DFSU · Dimensional ETF Trust | 0,00% | 407 NS | 30 de abril de 2026 | N-PORT |