TARA Protara Therapeutics, Inc. - Common Stock
$4,08
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 11, 2026
Rango 52S
$3–$8
23% of range
Calificación del Analista
BUY
14 analysts
Precio Objetivo
$27
+552% upside
P/E (TTM)
-3.0
ROE
-33.7%
Margen de Beneficio Neto
—
Acerca de Protara Therapeutics, Inc. - Common Stock Descripción general de la empresa de Wikipedia
Proteon Therapeutics, Inc. is a developer of pharmaceuticals with offices in Waltham, Massachusetts and Kansas City, Missouri.
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Proteon Therapeutics, Inc. is a developer of pharmaceuticals with offices in Waltham, Massachusetts and Kansas City, Missouri.
Company History
Proteon was founded by Dr. F. Nicholas Franano based on technology created at Johns Hopkins University. Major investors in the company include MPM Capital, Rockhill Partners, TVM Capital, Skyline Ventures, Prism VentureWorks, Vectis Life Sciences and Intersouth Partners. They have invested over $72 million in the company.
The company is led by Timothy Noyes, CEO; Steven Burke, CMO; George Eldridge, CFO; and Scott Toner, director of marketing.
On March 5, 2009, the company announced that it had raised $32 million from its existing investors plus MPM Capital and Vectis Life Sciences. Proteon also announced that it had entered into an option agreement to be acquired by Novartis for up to $550 million. The company went public in 2014.
In September 2019, Proteon Therapeutics merged with ArTara Therapeutics.
PRT-201
Proteon is developing PRT-201 (vonapanitase), a drug to improve blood flow following vascular surgery procedures, and, more broadly, is interested in vascular access for hemodialysis and peripheral arterial disease (PAD). PRT-201 is a recombinant human elastase manufactured for Proteon by Lonza.
In September 2008, the company announced that the Food and Drug Administration had granted fast track status to PRT-201.
In December 2016, they announced that the phase III trial of PRT-201 hadn't reached its primary endpoint, causing Proteon's stock price to drop more than 75%.
Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗
TARA Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$4.08
Capitalización Bursátil
$218M
P/E (TTM)
-3.0
BPA (TTM)
$-1.34
Ingresos (TTM)
—
Rendimiento div.
—
ROE
-33.7%
Deuda/Capital
—
Rango 52S
$3 – $8
TARA Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-1.34
2021-12-31
→
2025-12-31
Flujo de caja libre
$-56M
2016-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
TARA
Mediana de Pares
P/E (TTM)
-3.0
88.5
P/B (P/C)
1.1
3.6
Price / FCF (Precio / FCF)
-3.9
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
TARA
Mediana de Pares
ROA
-29.4%
-38.8%
ROE
-33.7%
-61.0%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
TARA
Mediana de Pares
Current Ratio (Ratio corriente)
14.6
3.9
Quick Ratio (Ratio Rápido)
14.2
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
TARA
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
TARA
Mediana de Pares
TARA Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
14 analistas
- Compra fuerte 3 21,4%
- Compra 10 71,4%
- Mantener 1 7,1%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
7 analistas · 2026-08-13
Mediana
$26.00
Media
$26.57
← Por Debajo de Todos los Objetivos
$4.08
Mín
$24.00
Máx
$30.00
Objetivo mediano
$26.00
+538,0%
Objetivo medio
$26.57
+552,1%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.07%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 31 de marzo de 2026 | $-0.31 | $-0.38 | 0.07% |
| 31 de diciembre de 2025 | $-0.37 | $-0.33 | -0.04% |
| 30 de septiembre de 2025 | $-0.31 | $-0.39 | 0.08% |
| 30 de junio de 2025 | $-0.35 | $-0.41 | 0.06% |
| 31 de marzo de 2025 | $-0.29 | $-0.46 | 0.17% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| TARA | $286M | -4.0 | — | — | -33.7% | — |
| CNXU | — | — | — | — | — | — |
| GLSI | $300M | -14.7 | — | — | -2159.7% | — |
| PYXS | $72M | -0.9 | -14.2% | -574.5% | -112.9% | — |
| RCEL | $105M | -2.0 | 11.5% | -67.8% | 328.9% | 82.1% |
| AKBA | $427M | -80.5 | 47.5% | -2.3% | -17.3% | — |
| ALEC | $172M | -1.1 | -79.1% | -679.2% | -280.7% | — |
| EBS | $644M | 13.3 | -28.8% | 7.1% | 9.9% | — |
| ARCT | $174M | -2.6 | -46.1% | -80.2% | -29.6% | — |
| NBP | — | — | — | — | — | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | · | · | · | $3M | |
| R&D Expense | $43M | $32M | $25M | $17M | $21M | $12M | $4M | $12M | $22M | $19M | $12M | $6M | |
| SG&A Expense | $22M | $17M | $19M | $21M | $26M | $22M | $4M | $10M | $9M | $10M | $8M | $4M | |
| Operating Expenses | $65M | $49M | $44M | $67M | $47M | $34M | $8M | $21M | $30M | $29M | $21M | $11M | |
| Operating Income | $-65M | $-49M | $-44M | $-67M | $-47M | $-34M | $-8M | $-21M | $-30M | $-29M | $-21M | $-8M | |
| Interest Expense | · | · | · | · | $0 | $34.0K | · | · | · | · | · | $857.0K | |
| Interest Income | $6M | $4M | $3M | $1M | $237.0K | $500.0K | · | · | · | · | · | · | |
| Other Non-op | $7M | $5M | $3M | $1M | $237.0K | $466.0K | · | $207.0K | $139.0K | $-14.0K | $-651.0K | $5M | |
| Pretax Income | $57M | $45M | · | · | · | · | $-15M | $-21M | $-30M | $-29M | $-21M | $-3M | |
| Income Tax | · | · | · | · | · | · | · | · | · | · | · | $-110.0K | |
| Net Income | $-57M | $-45M | $-40M | $-66M | $-47M | $-34M | $-8M | $-21M | $-30M | $-29M | $-21M | $-3M | |
| EPS (Basic) | $-1.34 | $-2.17 | $-3.57 | $-5.86 | $-4.21 | · | · | · | · | · | · | · | |
| EPS (Diluted) | $-1.34 | $-2.17 | $-3.57 | $-5.86 | $-4.21 | · | · | · | · | · | · | · | |
| Shares (Basic) | 42,836,129 | 20,592,847 | 11,331,338 | 11,259,615 | · | · | · | · | · | · | · | · | |
| Shares (Diluted) | 42,836,129 | 20,592,847 | 11,331,338 | 11,259,615 | 11,232,576 | · | · | · | · | · | · | · | |
| EBITDA | $-65M | $-49M | $-44M | $-67M | $-47M | $-34M | $-15M | · | · | $-29M | $-21M | $-8M |
Balance general 23
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $50M | $163M | $40M | $24M | $36M | $169M | $564.0K | $19M | $21M | $36M | $40M | $69M | |
| Short-term Investments | $106M | $7M | $26M | $60M | $56M | · | · | $2M | $21M | $5M | $25M | $15M | |
| Prepaid Expense | $4M | $2M | $3M | $2M | $2M | $787.0K | $78.0K | $1M | $1M | $1M | $1M | $1M | |
| Other Current Assets | $65.0K | $2.0K | $37.0K | $127.0K | $34.0K | $52.0K | · | · | · | · | · | · | |
| Current Assets | $160M | $172M | $69M | $86M | $93M | $169M | $764.0K | $23M | $43M | $43M | $67M | $85M | |
| PP&E (Net) | $759.0K | $1M | $1M | $2M | $2M | $1M | $459.0K | $263.0K | $259.0K | $372.0K | $224.0K | $83.0K | |
| PP&E (Gross) | $2M | $2M | $2M | $2M | $2M | $1M | $475.0K | $1M | $971.0K | $937.0K | $665.0K | $467.0K | |
| Accum. Depreciation | $1M | $1M | $824.0K | $483.0K | $236.0K | $119.0K | $16.0K | $827.0K | $712.0K | $565.0K | $441.0K | $384.0K | |
| Goodwill | · | · | · | · | $30M | $30M | · | · | · | · | · | · | |
| Other Non-current Assets | $20.0K | $27.0K | $11.0K | $16.0K | $865.0K | $1M | · | · | $218.0K | $393.0K | $706.0K | $114.0K | |
| Total Assets | $209M | $181M | $79M | $113M | $173M | $203M | $1M | $24M | $44M | $44M | $68M | $85M | |
| Accounts Payable | $3M | $4M | $2M | $2M | $954.0K | $914.0K | $716.0K | $441.0K | $291.0K | $556.0K | $1M | $917.0K | |
| Accrued Liabilities | $6M | $5M | $3M | $3M | $2M | $2M | $3M | $3M | $9M | $5M | $3M | $1M | |
| Current Liabilities | $11M | $11M | $6M | $6M | $4M | $3M | $3M | $3M | $9M | $5M | $4M | $2M | |
| Capital Leases | $2M | $3M | $4M | $5M | $6M | $999.0K | · | · | · | · | · | · | |
| Total Liabilities | $13M | $14M | $11M | $11M | $11M | $4M | $3M | $3M | $9M | $5M | $4M | $2M | |
| Common Stock | $54.0K | $35.0K | $11.0K | $11.0K | $11.0K | $11.0K | $3.0K | · | $18.0K | $17.0K | $16.0K | $16.0K | |
| Paid-in Capital | $499M | $412M | $269M | $263M | $256M | $246M | $11M | $209M | $203M | $198M | $195M | $192M | |
| Retained Earnings | $-302M | $-245M | $-200M | $-160M | $-94M | $-47M | $-13M | $-210M | $-190M | $-160M | $-131M | $-110M | |
| AOCI | $90.0K | $2.0K | $-31.0K | $-688.0K | $-211.0K | · | $3.0K | $5.0K | $-14.0K | · | $-11.0K | $-6.0K | |
| Stockholders' Equity | $196M | $167M | $68M | $102M | $162M | $199M | $-2M | $5M | $35M | $38M | $63M | $82M | |
| Liabilities + Equity | $209M | $181M | $79M | $113M | $173M | $203M | $1M | $24M | $44M | $44M | $68M | $85M | |
| Shares Outstanding | 53,587,260 | 35,044,772 | 11,364,903 | 11,267,389 | 11,235,731 | 11,211,840 | 2,627,533 | 481,091 | 17,674,729 | 16,603,559 | 16,501,500 | 16,448,455 |
Flujo de Efectivo 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | · | · | · | · | $123.0K | $57.0K | $30.0K | |
| Stock-based Comp | $4M | $4M | $6M | $7M | $10M | $10M | $424.0K | $3M | $3M | $3M | $2M | $459.0K | |
| Deferred Tax | $-11M | $-20M | $-14M | $-9M | $-5M | $-9M | · | · | · | · | · | · | |
| Restructuring | · | · | · | · | · | · | $3M | · | · | · | · | · | |
| Other Non-cash | · | · | · | · | · | · | · | · | · | $1M | $2M | $-7M | |
| Operating Cash Flow | $-56M | $-36M | $-38M | $-26M | $-35M | $-23M | $-5M | $-23M | $-22M | $-24M | $-18M | $-10M | |
| CapEx | $94.0K | $63.0K | $45.0K | $120.0K | $596.0K | $884.0K | $475.0K | $119.0K | $35.0K | $271.0K | $198.0K | $51.0K | |
| Investing Cash Flow | $-139M | $19M | $53M | $15M | $-98M | $3M | $-475.0K | $18M | $-16M | $20M | $-11M | · | |
| Stock Issued | · | · | · | · | · | $74M | · | · | · | · | · | $62M | |
| Stock Repurchased | · | · | $91.0K | $90.0K | $228.0K | · | · | · | · | · | · | · | |
| Net Stock Activity | · | · | $-91.0K | $-90.0K | $-228.0K | $66M | · | · | · | · | · | $62M | |
| Financing Cash Flow | $83M | $140M | $-91.0K | $-90.0K | $-228.0K | $189M | $500.0K | $3M | $23M | $208.0K | $163.0K | · | |
| Net Change in Cash | · | · | · | · | · | · | $-13M | $-2M | $-15M | $-4M | $-29M | $66M | |
| Free Cash Flow | $-56M | $-36M | $-38M | $-27M | $-35M | $-24M | $-16M | · | · | $-24M | $-18M | $-10M |
Rentabilidad 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | -7391.4% | · | · | · | · | · | -257.1% | |
| Net Margin | · | · | · | · | · | -7291.4% | · | · | · | · | · | -113.4% | |
| EBITDA Margin | · | · | · | · | · | -7391.4% | · | · | · | · | · | -256.1% | |
| ROA | -29.4% | -34.2% | -42.0% | -46.1% | -25.1% | -33.2% | -98.3% | · | · | -51.4% | -28.1% | -7.4% | |
| ROE | -33.7% | -35.8% | -55.6% | -54.7% | -28.4% | -17.2% | -449.1% | · | · | -56.0% | -29.3% | 37.0% |
Liquidez y Solvencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.6 | 15.7 | 11.2 | 15.0 | 21.7 | 58.1 | 12.0 | · | · | 8.4 | 16.1 | 36.2 | |
| Quick Ratio | 14.2 | 15.5 | 10.7 | 14.7 | 21.2 | 57.8 | 10.6 | · | · | 8.1 | 15.8 | 35.8 | |
| Interest Coverage | · | · | · | · | · | -1013.1 | · | · | · | · | · | -8.8 |
Eficiencia 1
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | 0.0 | · | · | · | · | · | 0.1 |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | · | · | · | · | · | · | · | · | · | · | $3M | |
| Net Income TTM | $-57M | $-45M | $-40M | $-66M | $-47M | $-34M | $-8M | $-21M | $-30M | $-29M | $-21M | $-3M | |
| Market Cap | $286M | $185M | $21M | $30M | $76M | $271M | $9M | · | · | $1.26B | $10.24B | $6.84B | |
| P/E | -4.0 | -2.4 | -0.5 | -0.5 | -1.6 | · | · | · | · | · | · | · | |
| P/S | · | · | · | · | · | · | · | · | · | · | · | 2321.1 | |
| P/B | 1.5 | 1.1 | 0.3 | 0.3 | 0.5 | 1.4 | 1.4 | · | · | 32.8 | 161.5 | 83.0 | |
| P / Tangible Book | 1.5 | 1.1 | 0.3 | 0.3 | 0.6 | 1.6 | · | · | · | · | · | · | |
| P / Cash Flow | -5.1 | -5.2 | -0.6 | -1.1 | -2.2 | -11.6 | -0.6 | · | · | -53.3 | -582.8 | -684.9 | |
| P / FCF | -5.1 | -5.2 | -0.6 | -1.1 | -2.2 | -11.2 | -0.6 | · | · | -52.7 | -576.3 | -681.5 | |
| Earnings Yield | -25.1% | -41.1% | -190.4% | -218.7% | -62.4% | · | · | · | · | · | · | · |
Estado de resultados 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $17M | $14M | $13M | $10M | $11M | $9M | $9M | $8M | $6M | $8M | $6M | $6M | $7M | $5M | $5M | $3M | |
| SG&A Expense | $6M | $6M | $6M | $5M | $6M | $5M | $5M | $4M | $4M | $4M | $5M | $4M | $5M | $5M | $5M | $5M | |
| Operating Expenses | $23M | $20M | $19M | $15M | $17M | $14M | $14M | $12M | $11M | $12M | $11M | $11M | $12M | $10M | $40M | $8M | |
| Operating Income | $-23M | $-20M | $-19M | $-15M | $-17M | $-14M | $-14M | $-12M | $-11M | $-12M | $-11M | $-11M | $-12M | $-10M | $-40M | $-8M | |
| Interest Income | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $756.0K | $820.0K | $840.0K | $846.0K | $687.0K | $542.0K | $283.0K | |
| Other Non-op | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $756.0K | $820.0K | $840.0K | $846.0K | $687.0K | $542.0K | $283.0K | |
| Net Income | $-22M | $-18M | $-17M | $-13M | $-15M | $-12M | $-13M | $-11M | $-10M | $-11M | $-10M | $-10M | $-11M | $-9M | $-39M | $-8M | |
| EPS (Basic) | $-0.36 | $-0.31 | $-0.39 | $-0.31 | $-0.35 | $-0.29 | $-0.25 | $-0.50 | $-0.45 | $-0.97 | $-0.90 | $-0.87 | $-1.00 | $-0.80 | $-3.46 | $-0.68 | |
| EPS (Diluted) | $-0.36 | $-0.31 | $-0.39 | $-0.31 | $-0.35 | $-0.29 | $-0.25 | $-0.50 | $-0.45 | $-0.97 | $-0.90 | $-0.87 | $-1.00 | $-0.80 | $-3.46 | $-0.68 | |
| Shares (Basic) | 61,006,766 | 57,538,833 | -82,414,767 | 42,272,104 | 42,270,855 | 40,707,937 | -34,391,036 | 22,329,772 | 21,233,163 | 11,420,948 | -22,628,260 | 11,347,887 | 11,307,842 | 11,303,869 | -22,511,202 | 11,265,475 | |
| Shares (Diluted) | 61,006,766 | 57,538,833 | -82,414,767 | 42,272,104 | 42,270,855 | 40,707,937 | -34,391,036 | 22,329,772 | 21,233,163 | 11,420,948 | -22,628,260 | 11,347,887 | 11,307,842 | 11,303,869 | -22,511,202 | 11,265,475 | |
| EBITDA | $-23M | $-20M | · | $-15M | $-17M | $-14M | · | $-12M | $-11M | $-12M | · | $-11M | $-12M | $-10M | · | $-8M |
Balance general 23
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $17M | $15M | $50M | $13M | $31M | $91M | $163M | $52M | $90M | $52M | $40M | $34M | $34M | $21M | $24M | $47M | |
| Short-term Investments | $125M | $121M | $106M | $120M | $91M | $33M | $7M | $30M | · | $3M | $26M | $40M | $46M | $66M | $60M | $49M | |
| Prepaid Expense | $4M | $4M | $4M | $3M | $3M | $2M | $2M | $4M | $3M | $3M | $3M | $4M | $4M | $8M | $2M | $2M | |
| Other Current Assets | $230.0K | $17.0K | $65.0K | $218.0K | $78.0K | $16.0K | $2.0K | $3.0K | $4.0K | $3.0K | $37.0K | $2.0K | $1.0K | $127.0K | $127.0K | · | |
| Current Assets | $146M | $140M | $160M | $136M | $125M | $127M | $172M | $85M | $92M | $58M | $69M | $78M | $84M | $95M | $86M | $99M | |
| PP&E (Net) | $1M | $669.0K | $759.0K | $828.0K | $912.0K | $988.0K | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $2M | |
| PP&E (Gross) | · | · | $2M | · | · | · | $2M | · | · | · | $2M | · | · | · | $2M | · | |
| Accum. Depreciation | · | · | $1M | · | · | · | $1M | · | · | · | $824.0K | · | · | · | $483.0K | · | |
| Goodwill | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $30M | |
| Other Non-current Assets | $74.0K | $76.0K | $20.0K | $21.0K | $29.0K | $35.0K | $27.0K | $33.0K | $19.0K | $31.0K | $11.0K | $3M | $3M | $586.0K | $16.0K | $734.0K | |
| Total Assets | $176M | $192M | $209M | $145M | $157M | $169M | $181M | $94M | $102M | $68M | $79M | $88M | $95M | $106M | $113M | $149M | |
| Accounts Payable | $5M | $4M | $3M | $5M | $5M | $2M | $4M | $2M | $1M | $972.0K | $2M | $3M | $2M | $4M | $2M | $456.0K | |
| Accrued Liabilities | $7M | $4M | $6M | $4M | $3M | $4M | $5M | $5M | $3M | $4M | $3M | $3M | $2M | $1M | $3M | $2M | |
| Current Liabilities | $13M | $9M | $11M | $10M | $10M | $7M | $11M | $9M | $6M | $6M | $6M | $7M | $5M | $6M | $6M | $4M | |
| Capital Leases | $1M | $2M | $2M | $2M | $3M | $3M | $3M | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $6M | |
| Total Liabilities | $15M | $11M | $13M | $12M | $13M | $10M | $14M | $12M | $10M | $10M | $11M | $12M | $10M | $12M | $11M | $9M | |
| Common Stock | $59.0K | $55.0K | $54.0K | $39.0K | $39.0K | $39.0K | $35.0K | $21.0K | $21.0K | $11.0K | $11.0K | $11.0K | $11.0K | $11.0K | $11.0K | $11.0K | |
| Paid-in Capital | $503M | $502M | $499M | $417M | $416M | $415M | $412M | $314M | $313M | $270M | $269M | $267M | $266M | $264M | $263M | $261M | |
| Retained Earnings | $-342M | $-320M | $-302M | $-285M | $-272M | $-257M | $-245M | $-232M | $-221M | $-211M | $-200M | $-190M | $-180M | $-169M | $-160M | $-121M | |
| AOCI | $-363.0K | $-364.0K | $90.0K | $143.0K | $77.0K | $89.0K | $2.0K | $29.0K | · | $-1.0K | $-31.0K | $-165.0K | $-336.0K | $-469.0K | $-688.0K | $-1M | |
| Stockholders' Equity | $161M | $181M | $196M | $132M | $144M | $158M | $167M | $82M | $92M | $58M | $68M | $77M | $85M | $95M | $102M | $139M | |
| Liabilities + Equity | $176M | $192M | $209M | $145M | $157M | $169M | $181M | $94M | $102M | $68M | $79M | $88M | $95M | $106M | $113M | $149M | |
| Shares Outstanding | 59,083,935 | 55,055,582 | 53,587,260 | 38,587,260 | 38,581,863 | 38,577,813 | 35,044,772 | 20,629,772 | 11,364,903 | 11,433,837 | 11,364,903 | 11,364,903 | 11,307,962 | 11,306,753 | 11,267,389 | 11,267,389 |
Flujo de Efectivo 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $1M | $1M | $1M | $1M | $903.0K | $833.0K | $904.0K | $931.0K | $1M | $1M | $1M | $1M | $2M | $2M | $1M | $1M | |
| Operating Cash Flow | $-15M | $-21M | $-17M | $-12M | $-12M | $-15M | $-9M | $-8M | $-8M | $-10M | $-9M | $-7M | $-9M | $-13M | $-5M | $-5M | |
| CapEx | · | · | $24.0K | $4.0K | $22.0K | $44.0K | $0 | $8.0K | · | · | $0 | $37.0K | $2.0K | $6.0K | $6.0K | $83.0K | |
| Investing Cash Flow | $18M | $-15M | $-27M | $-7M | $-48M | $-58M | $22M | $-29M | $3M | $23M | $15M | $6M | $22M | $10M | $-18M | $19M | |
| Stock Repurchased | · | · | · | · | · | · | · | · | · | $76.0K | · | $27.0K | $0 | $64.0K | $0 | $18.0K | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $-76.0K | · | · | · | $-64.0K | · | · | |
| Financing Cash Flow | $-26.0K | $1M | $81M | $13.0K | $8.0K | $2M | $98M | $0 | $42M | $-76.0K | $0 | $-27.0K | $0 | $-64.0K | $0 | $-18.0K | |
| Free Cash Flow | · | · | · | · | · | $-15M | · | · | · | · | · | · | · | $-13M | · | · |
Rentabilidad 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1575.9% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Net Margin | -1464.0% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -1575.9% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| ROA | -13.0% | -9.9% | · | -11.1% | -11.6% | -10.1% | · | -12.3% | -9.7% | -12.7% | · | -8.3% | -9.0% | -6.8% | · | -4.7% | |
| ROE | -14.2% | -10.5% | · | -12.4% | -12.7% | -11.0% | · | -14.1% | -10.7% | -14.5% | · | -9.1% | -9.8% | -7.3% | · | -5.0% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 11.0 | 15.7 | · | 13.7 | 12.8 | 18.0 | · | 9.8 | 16.3 | 10.5 | · | 11.5 | 17.1 | 14.8 | · | 26.6 | |
| Quick Ratio | 10.7 | 15.2 | · | 13.4 | 12.5 | 17.7 | · | 9.4 | 15.9 | 10.0 | · | 10.9 | 16.3 | 13.5 | · | 26.0 |
Eficiencia 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-68M | $-58M | · | $-51M | $-48M | $-44M | · | $-42M | $-42M | $-41M | · | $-38M | $-37M | $-36M | · | $-38M | |
| Market Cap | $226M | $287M | · | $168M | $117M | $164M | · | $38M | $24M | $46M | · | $19M | $27M | $35M | · | $33M | |
| P/E | -2.9 | -4.1 | · | -3.0 | -1.9 | -1.9 | · | -0.7 | -0.6 | -1.1 | · | -0.5 | -0.7 | -1.0 | · | -0.9 | |
| P/B | 1.4 | 1.6 | · | 1.3 | 0.8 | 1.0 | · | 0.5 | 0.3 | 0.8 | · | 0.2 | 0.3 | 0.4 | · | 0.2 | |
| P / Tangible Book | 1.4 | 1.6 | · | 1.3 | 0.8 | 1.0 | · | 0.5 | 0.3 | 0.8 | · | 0.2 | 0.3 | 0.4 | · | 0.3 | |
| P / Cash Flow | · | -13.4 | · | · | · | -11.2 | · | · | · | -4.4 | · | · | · | -2.7 | · | · | |
| P / FCF | · | · | · | · | · | -11.1 | · | · | · | · | · | · | · | -2.7 | · | · | |
| Earnings Yield | -34.8% | -24.2% | · | -33.3% | -52.5% | -51.9% | · | -152.5% | -158.2% | -90.8% | · | -200.6% | -135.6% | -102.2% | · | -113.5% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-57M | $-45M | $-40M | $-66M | $-47M |
| EPS Diluido | $-1.34 | $-2.17 | $-3.57 | $-5.86 | $-4.21 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 14.6 | 15.7 | 11.2 | 15.0 | 21.7 |
| Ratio Rápido | 14.2 | 15.5 | 10.7 | 14.7 | 21.2 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-56M | $-36M | $-38M | $-27M | $-35M |
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Propietarios institucionales (13F) 127 declarantes · $162.3M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 31 (+4 vs trimestre anterior) | 16 (-5 vs trimestre anterior) | 39 (-8 vs trimestre anterior) | 33 (+10 vs trimestre anterior) | +760K |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | $27 154 562 | 5 207 011 | 16,73% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $11 846 454 | 3 101 166 | 7,30% | Acciones |
| Velan Capital Investment Management LP | $10 866 571 | 2 844 652 | 6,70% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $8 786 508 | 2 300 133 | 5,41% | Acciones |
| Blackstone Inc. | $8 654 263 | 2 265 514 | 5,33% | Acciones |
| ORBIMED ADVISORS LLC | $8 480 400 | 2 220 000 | 5,23% | Acciones |
| Sio Capital Management, LLC | $7 341 551 | 1 921 872 | 4,52% | Acciones |
| ACORN CAPITAL ADVISORS, LLC | $6 693 079 | 1 752 115 | 4,12% | Acciones |
| Integral Health Asset Management, LLC | $5 730 000 | 1 500 000 | 3,53% | Acciones |
| 5AM Venture Management, LLC | $5 232 567 | 1 369 782 | 3,22% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $4 362 540 | 1 141 710 | 2,69% | Acciones |
| STATE STREET CORP | $4 080 887 | 1 068 295 | 2,51% | Acciones |
| Qube Research & Technologies Ltd | $3 993 871 | 1 045 516 | 2,46% | Acciones |
| Balyasny Asset Management L.P. | $3 921 960 | 1 026 691 | 2,42% | Acciones |
| BAKER BROS. ADVISORS LP | $3 711 565 | 971 614 | 2,29% | Acciones |
| ADAR1 Capital Management, LLC | $3 592 756 | 940 512 | 2,21% | Acciones |
| CITADEL ADVISORS LLC | $3 414 045 | 893 729 | 2,10% | Acciones |
| BANK OF AMERICA CORP /DE/ | $3 287 679 | 860 649 | 2,03% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $2 389 918 | 625 633 | 1,47% | Acciones |
| Point72 Asset Management, L.P. | $2 096 920 | 548 932 | 1,29% | Acciones |
| Catalio Capital Management, LP | $1 986 965 | 520 148 | 1,22% | Acciones |
| GOLDMAN SACHS GROUP INC | $1 936 106 | 506 834 | 1,19% | Acciones |
| Walleye Capital LLC | $1 930 750 | 505 432 | 1,19% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 878 130 | 491 657 | 1,16% | Acciones |
| MORGAN STANLEY | $1 833 917 | 480 083 | 1,13% | Acciones |
| UBS Group AG | $1 723 538 | 451 188 | 1,06% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $1 278 489 | 334 683 | 0,79% | Acciones |
| Verdad Advisers, LP | $1 192 791 | 312 249 | 0,73% | Acciones |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1 129 058 | 295 565 | 0,70% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $960 730 | 251 500 | 0,59% | Acciones |
| OPPENHEIMER & CO INC | $910 543 | 238 362 | 0,56% | Acciones |
| Jump Financial, LLC | $775 842 | 203 100 | 0,48% | Acciones |
| CIBC WORLD MARKET INC. | $636 011 | 166 495 | 0,39% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $603 449 | 157 971 | 0,37% | Acciones |
| J. Goldman & Co LP | $515 700 | 135 000 | 0,32% | Acciones |
| SUPERSTRING CAPITAL MANAGEMENT LP | $463 966 | 121 457 | 0,29% | Acciones |
| Fisher Asset Management, LLC | $380 342 | 99 566 | 0,23% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $376 220 | 98 487 | 0,23% | Acciones |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $325 961 | 85 330 | 0,20% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $266 071 | 69 652 | 0,16% | Acciones |
| FMR LLC | $260 012 | 68 066 | 0,16% | Acciones |
| XTX Topco Ltd | $244 281 | 63 948 | 0,15% | Acciones |
| RHUMBLINE ADVISERS | $241 589 | 63 245 | 0,15% | Acciones |
| TRUIST FINANCIAL CORP | $229 200 | 60 000 | 0,14% | Acciones |
| Assenagon Asset Management S.A. | $229 024 | 59 954 | 0,14% | Acciones |
| Trexquant Investment LP | $227 733 | 59 616 | 0,14% | Acciones |
| DEUTSCHE BANK AG\ | $220 464 | 57 713 | 0,14% | Acciones |
| ALPS ADVISORS INC | $217 897 | 57 041 | 0,13% | Acciones |
| AMERIPRISE FINANCIAL INC | $214 863 | 56 247 | 0,13% | Acciones |
| PRUDENTIAL FINANCIAL INC | $193 789 | 50 730 | 0,12% | Acciones |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | $191 000 | 50 000 | 0,12% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $154 252 | 40 380 | 0,10% | Acciones |
| Alyeska Investment Group, L.P. | $151 753 | 39 726 | 0,09% | Acciones |
| Quadrature Capital Ltd | $150 199 | 39 319 | 0,09% | Acciones |
| Marex Group Ltd | $134 655 | 35 250 | 0,08% | Acciones |
| WINTON GROUP Ltd | $125 296 | 32 800 | 0,08% | Acciones |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $113 454 | 29 700 | 0,07% | Acciones |
| MetLife Investment Management, LLC | $108 404 | 28 378 | 0,07% | Acciones |
| MARSHALL WACE, LLP | $106 995 | 28 009 | 0,07% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $93 988 | 18 040 | 0,06% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $92 043 | 24 095 | 0,06% | Acciones |
| WOLVERINE TRADING, LLC | $88 200 | 20 000 | 0,05% | Opción de venta |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $87 478 | 22 900 | 0,05% | Opción de venta |
| CITIGROUP INC | $80 698 | 21 125 | 0,05% | Acciones |
| Jain Global LLC | $80 220 | 21 000 | 0,05% | Acciones |
| Invesco Ltd. | $78 295 | 20 496 | 0,05% | Acciones |
| Vanguard Global Advisers, LLC | $76 885 | 20 127 | 0,05% | Acciones |
| PRELUDE CAPITAL MANAGEMENT, LLC | $74 922 | 19 613 | 0,05% | Acciones |
| EntryPoint Capital, LLC | $73 673 | 19 286 | 0,05% | Acciones |
| LPL Financial LLC | $73 077 | 19 130 | 0,05% | Acciones |
| VANGUARD GROUP INC | $70 479 | 13 223 | 0,04% | Acciones |
| Squarepoint Ops LLC | $69 234 | 18 124 | 0,04% | Acciones |
| IEQ CAPITAL, LLC | $68 489 | 17 929 | 0,04% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $67 114 | 17 569 | 0,04% | Acciones |
| BARCLAYS PLC | $60 665 | 15 881 | 0,04% | Acciones |
| BlackRock, Inc. | $58 950 | 15 432 | 0,04% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $56 834 | 14 878 | 0,04% | Acciones |
| INTECH INVESTMENT MANAGEMENT LLC | $51 807 | 13 562 | 0,03% | Acciones |
| WOLVERINE TRADING, LLC | $51 315 | 11 636 | 0,03% | Acciones |
| Mariner, LLC | $45 441 | 11 899 | 0,03% | Acciones |
| Bank of New York Mellon Corp | $43 877 | 11 486 | 0,03% | Acciones |
| VOYA INVESTMENT MANAGEMENT LLC | $43 812 | 11 469 | 0,03% | Acciones |
| D. E. Shaw & Co., Inc. | $42 452 | 11 113 | 0,03% | Acciones |
| COMMONWEALTH EQUITY SERVICES, LLC | $42 020 | 11 000 | 0,03% | Acciones |
| WELLS FARGO & COMPANY/MN | $41 161 | 10 775 | 0,03% | Acciones |
| Essential Partners LLC | $37 444 | 9 802 | 0,02% | Acciones |
| MERCER GLOBAL ADVISORS INC /ADV | $34 525 | 9 038 | 0,02% | Acciones |
| NORTHERN TRUST CORP | $32 061 | 8 393 | 0,02% | Acciones |
| CWM, LLC | $30 458 | 5 846 | 0,02% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $30 178 | 7 900 | 0,02% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $28 788 | 7 536 | 0,02% | Acciones |
| Tower Research Capital LLC (TRC) | $19 062 | 4 990 | 0,01% | Acciones |
| Legal & General Group Plc | $17 129 | 4 490 | 0,01% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $14 645 | 2 811 | 0,01% | Acciones |
| Ameritas Investment Partners, Inc. | $12 598 | 3 298 | 0,01% | Acciones |
| Nuveen, LLC | $9 642 | 2 524 | 0,01% | Acciones |
| Integrated Wealth Concepts LLC | $6 684 | 1 750 | 0,00% | Acciones |
| Arax Advisory Partners | $6 383 | 1 671 | 0,00% | Acciones |
| Russell Investments Group, Ltd. | $6 085 | 1 593 | 0,00% | Acciones |
| ROYAL BANK OF CANADA | $6 000 | 1 577 | 0,00% | Acciones |
Informantes de la empresa 40 insiders · 16 directivos · 20 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Jesse Shefferman | CEO and President | 29 de junio de 2026 M | 691 832 | 0 | 1 | $-882 160 |
| Timothy P Noyes | President and CEO | 31 de enero de 2019 A | 0 | 0 | 0 | $0 |
| Patrick Fabbio | Chief Financial Officer | 26 de enero de 2026 F | 64 115 | 0 | 0 | $0 |
| Blaine Davis | Chief Financial Officer | 15 de julio de 2022 F | 20 662 | 0 | 0 | $0 |
| George Arthur Eldridge, | Sr VP, CFO, Treasr, Asst Secy | 18 de enero de 2019 A | 29 132 | 0 | 0 | $0 |
| William Conkling | Chief Commercial Officer | 2 de junio de 2026 F | 69 992 | 0 | 0 | $0 |
| Jacqueline Zummo | Chief R&D Officer | 8 de abril de 2026 S | 94 827 | 0 | 2 | $-124 989 |
| Hannah Fry | VP, Controller | 26 de enero de 2026 F | 42 723 | 0 | 0 | $0 |
| Leonardo Viana Nicacio | Chief Medical Officer | 16 de enero de 2026 A | 78 181 | 0 | 0 | $0 |
| Jathin Bandari | Chief Medical Officer | 19 de enero de 2024 A | 56 704 | 0 | 0 | $0 |
| Julio Casoy | Chief Medical Officer | 9 de enero de 2020 A | 45 500 | 0 | 0 | $0 |
| Steven Keith Burke | SVP and Chief Medical Officer | 15 de marzo de 2019 G | 26 332 | 0 | 0 | $0 |
| Bradley J Hartman | VP, People | 18 de enero de 2019 A | — | 0 | 0 | $0 |
| Matthew Paul Kowalsky | VP, Legal and Secretary | 18 de enero de 2019 A | 29 479 | 0 | 0 | $0 |
| Scott E. Toner | Senior VP of Commercial | 18 de enero de 2019 A | 23 357 | 0 | 0 | $0 |
| Gottlieb Daniel Philip | VP Corporate Development | 18 de enero de 2019 A | 244 | 0 | 0 | $0 |
| Michael Edward Solomon | Consejero | 15 de junio de 2026 A | 26 500 | 0 | 0 | $0 |
| Jane Huang | Consejero | 15 de junio de 2026 A | — | 0 | 0 | $0 |
| Barry P Flannelly | Consejero | 15 de junio de 2026 A | — | 0 | 0 | $0 |
| Cynthia Smith | Consejero | 15 de junio de 2026 A | — | 0 | 0 | $0 |
| Richard S Levy | Consejero | 15 de junio de 2026 A | 51 000 | 0 | 0 | $0 |
| Roger Garceau | Consejero | 15 de junio de 2026 A | 33 000 | 0 | 0 | $0 |
| Gregory Sargen | Consejero | 15 de junio de 2026 A | 31 000 | 0 | 0 | $0 |
| Luke M Beshar | Consejero | 15 de junio de 2026 A | 198 000 | 0 | 0 | $0 |
| Scott Braunstein | Consejero | 9 de junio de 2020 A | 26 500 | 0 | 0 | $0 |
| John Gordon Freund | Consejero | 8 de noviembre de 2019 C | 2 175 882 | 0 | 0 | $0 |
| Hubert Birner | Consejero | 8 de junio de 2018 A | 1 943 059 | 0 | 0 | $0 |
| Paul J Hastings | Consejero | 8 de junio de 2018 A | — | 0 | 0 | $0 |
| Scott A Canute | Consejero | 8 de junio de 2018 A | — | 0 | 0 | $0 |
| Garen G Bohlin | Consejero | 8 de junio de 2018 A | 53 312 | 0 | 0 | $0 |
| Jonathan S Leff | Consejero | 8 de junio de 2018 A | — | 0 | 0 | $0 |
| Brendan O'Leary | Consejero | 9 de junio de 2016 A | 1 387 198 | 0 | 0 | $0 |
| Dmitry Kobyzev | Consejero | 2 de junio de 2015 A | 1 165 344 | 0 | 0 | $0 |
| Gregory D Phelps | Consejero | 2 de junio de 2015 A | — | 0 | 0 | $0 |
| Opaleye, L.P. | Propietario del 10% | 9 de enero de 2020 A | 2 208 472 | 0 | 0 | $0 |
| Martin Sebastian Olivo | — | 10 de junio de 2021 P | 14 344 | 0 | 0 | $0 |
| Randall Marshall | — | 14 de septiembre de 2020 S | 585 600 | 0 | 0 | $0 |
| Timothy Haines | — | 12 de noviembre de 2019 C | 2 144 517 | 0 | 0 | $0 |
| Abingworth LLP | — | 12 de noviembre de 2019 C | 2 144 517 | 0 | 0 | $0 |
| Stuart A Kingsley | — | 8 de junio de 2018 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 8 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Deerfield Partners, L.P., Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt IV, L.P., Deerfield Management Company, L.P., James E. Flynn | 8 de enero de 2021 | — | Presentación inicial | — | SEC |
| Opaleye Management Inc., Opaleye, L.P., James Silverman ×3 presentaciones | 25 de septiembre de 2020 | — | Presentación inicial | — | SEC |
| Deerfield Special Situations Fund, L.P., Deerfield Partners, L.P., Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt IV, L.P., Deerfield Management Company, L.P., James E. Flynn ×6 presentaciones | 17 de enero de 2020 | — | Presentación inicial | — | SEC |
| Abingworth LLP, Abingworth Bioventures VI, LP | 17 de enero de 2020 | — | Presentación inicial | M&A / venta | SEC |
| Abingworth LLP 98-051-8585, Abingworth Bioventures VI, LP 98-040-3543 ×3 presentaciones | 14 de noviembre de 2019 | — | Presentación inicial | Campaña de la junta directiva | SEC |
| TVM Life Science Ventures VI L.P., TVM Life Science Ventures VI GmbH & Co. KG, TVM Life Science Ventures Management VI L.P., Hubert Birner, Stefan Fischer, Helmut Schuehsler ×2 presentaciones | 2 de agosto de 2017 | — | Presentación inicial | Inversión pasiva | SEC |
| Deerfield Mgmt, L.P., Deerfield Management Company, L.P., Deerfield Mgmt III, L.P., Deerfield Special Situations Fund, L.P., Deerfield Partners, L.P., Deerfield International Master Fund, L.P., Deerfield Private Design Fund III, L.P., James E. Flynn | 29 de junio de 2017 | — | Presentación inicial | — | SEC |
| Skyline Venture Partners Qualified Purchaser Fund IV, L.P., Skyline Venture Management IV, LLC, John G. Freund, Yasunori Kaneko | 3 de noviembre de 2014 | — | Presentación inicial | Inversión pasiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 22 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 0,16% | 55 748 NS | 31 de mayo de 2026 | N-PORT |
| IWC · iShares Trust | 0,05% | 175 831 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,03% | 141 979 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,02% | 91 844 NS | 31 de mayo de 2026 | N-PORT |
| IWN · iShares Trust | 0,01% | 470 658 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,01% | 300 912 SH | 8 de agosto de 2026 | Diario |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 45 581 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,01% | 22 265 NS | 30 de abril de 2026 | N-PORT |
| IWM · iShares Trust | 0,01% | 1 336 607 SH | 8 de agosto de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,01% | 179 929 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 2 419 NS | 31 de mayo de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,01% | 3 715 NS | 30 de abril de 2026 | N-PORT |
| UWM · ProShares Trust | 0,00% | 1 891 NS | 31 de mayo de 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 1 912 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 48 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 5 791 NS | 30 de abril de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 18 477 NS | 30 de abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 7 914 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 20 174 NS | 30 de abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 586 965 SH | 8 de agosto de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 657 879 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 3 185 SH | 8 de agosto de 2026 | Diario |