ZBIO Zenas BioPharma, Inc. - Common Stock
$31,91
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 13, 2026
Rango 52S
$14–$45
59% of range
Calificación del Analista
STRONG BUY
14 analysts
Precio Objetivo
$44
+36% upside
P/E (TTM)
-3.8
ROE
-156.8%
Margen de Beneficio Neto
-3777.4%
ZBIO Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$31.91
Capitalización Bursátil
$1.74B
P/E (TTM)
-3.8
BPA (TTM)
$-8.44
Ingresos (TTM)
$10M
Rendimiento div.
—
ROE
-156.8%
Deuda/Capital
0.3
Rango 52S
$14 – $45
ZBIO Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$10M
2023-12-31
→
2025-12-31
BPA
$-8.44
2023-12-31
→
2025-12-31
Flujo de caja libre
$-172M
2024-12-31
→
2025-12-31
Márgenes
-3777.4%
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
ZBIO
Mediana de Pares
P/E (TTM)
-3.8
27.2
P/S (TTM) (P/V (TTM))
173.8
25.4
P/B (P/C)
7.2
5.1
EV / EBITDA
-3.8
—
Price / FCF (Precio / FCF)
-10.1
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
ZBIO
Mediana de Pares
Operating Margin (Margen Operativo)
-3830.6%
—
Net Profit Margin (Margen de Beneficio Neto)
-3777.4%
-473.7%
ROA
-100.2%
-40.2%
ROE
-156.8%
-50.4%
ROIC
-119.4%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
ZBIO
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
0.3
—
Current Ratio (Ratio corriente)
5.6
9.0
Quick Ratio (Ratio Rápido)
5.5
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
ZBIO
Mediana de Pares
Revenue YoY (Ingresos interanuales)
100.0%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
ZBIO
Mediana de Pares
ZBIO Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
14 analistas
- Compra fuerte 7 50,0%
- Compra 5 35,7%
- Mantener 2 14,3%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
8 analistas · 2026-08-15
Mediana
$44.50
Ahora
$31.91
Mín
$22.00
Máx
$59.00
Objetivo mediano
$44.50
+39,5%
Objetivo medio
$43.50
+36,3%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
-1.1%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 31 de marzo de 2026 | $-1.46 | $-1.62 | 0.16% |
| 31 de diciembre de 2025 | $-4.54 | $-1.05 | -3.5% |
| 30 de septiembre de 2025 | $-1.22 | $-1.07 | -0.15% |
| 30 de junio de 2025 | $-1.25 | $-1.07 | -0.18% |
| 31 de marzo de 2025 | $-0.80 | $-1.13 | 0.33% |
| 31 de diciembre de 2024 | $-3.99 | $-1.02 | -3.0% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| ZBIO | $1.98B | -4.3 | 100.0% | -3777.4% | -156.8% | — |
| PGEN | $1.48B | -3.1 | 146.7% | -2588.2% | 3159.1% | — |
| ADMA | $4.34B | 30.4 | 19.6% | 28.8% | 33.6% | 57.4% |
| VRDN | $3.17B | -7.7 | 23359.9% | -483.6% | -55.4% | — |
| STOK | $1.87B | -264.5 | 404.5% | -3.7% | -2.0% | — |
| GENB | — | — | — | — | — | — |
| AGIO | $1.59B | -3.8 | 48.0% | -764.0% | -32.2% | — |
| TSHA | $1.57B | -16.2 | 17.3% | -1115.3% | -44.0% | — |
| DMRA | — | — | 38.3% | -17981.1% | -167.0% | — |
| SRPT | $2.26B | -3.0 | 15.6% | -32.5% | -57.1% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 15
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $10M | $5M | $50M | |
| R&D Expense | $168M | $139M | $60M | |
| SG&A Expense | $53M | $30M | $17M | |
| Operating Expenses | $393M | $169M | $87M | |
| Operating Income | $-383M | $-164M | $-37M | |
| Interest Income | $12M | $8M | · | |
| Other Non-op | $417.0K | $202.0K | $624.0K | |
| Pretax Income | $-378M | $-157M | $-37M | |
| Income Tax | $-79.0K | $429.0K | $301.0K | |
| Net Income | $-378M | $-157M | $-37M | |
| EPS (Basic) | $-8.44 | $-11.89 | $-24.25 | |
| EPS (Diluted) | $-8.44 | $-11.89 | $-24.25 | |
| Shares (Basic) | 44,730,052 | 13,198,960 | 1,531,178 | |
| Shares (Diluted) | 44,730,052 | 13,198,960 | 1,531,178 | |
| EBITDA | $-383M | $-164M | · |
Balance general 20
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $111M | $320M | $57M | |
| Short-term Investments | $233M | $31M | · | |
| Prepaid Expense | $8M | $5M | $3M | |
| Current Assets | $351M | $356M | $60M | |
| PP&E (Net) | $34.0K | $185.0K | $193.0K | |
| Other Non-current Assets | $14M | $13M | $7M | |
| Total Assets | $384M | $370M | $68M | |
| Accounts Payable | $7M | $17M | $5M | |
| Accrued Liabilities | $54M | $39M | $17M | |
| Current Liabilities | $63M | $57M | $23M | |
| Capital Leases | $211.0K | $218.0K | $257.0K | |
| Total Liabilities | $141M | $58M | $44M | |
| Total Debt | $79M | · | · | |
| Common Stock | $5.0K | $4.0K | · | |
| Paid-in Capital | $1.01B | $700M | $5M | |
| Retained Earnings | $-765M | $-387M | $-230M | |
| AOCI | $-64.0K | $194.0K | $37.0K | |
| Stockholders' Equity | $242M | $312M | $-226M | |
| Liabilities + Equity | $384M | $370M | $68M | |
| Shares Outstanding | 54,485,518 | 41,793,412 | 1,576,854 |
Flujo de Efectivo 8
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Stock-based Comp | $26M | $11M | $3M | |
| Operating Cash Flow | $-172M | $-120M | $-31M | |
| CapEx | $18.0K | $131.0K | $17.0K | |
| Investing Cash Flow | $-252M | $-31M | $-17.0K | |
| Financing Cash Flow | $215M | $413M | $20M | |
| Net Change in Cash | $-209M | $263M | $-10M | |
| Taxes Paid | $15.0K | · | · | |
| Free Cash Flow | $-172M | $-120M | · |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -3830.6% | -3277.8% | · | |
| Net Margin | -3777.4% | -3139.8% | · | |
| Pretax Margin | -3778.2% | -3131.2% | · | |
| EBITDA Margin | -3830.6% | -3277.8% | · | |
| ROA | -100.2% | -71.7% | · | |
| ROE | -156.8% | -46.7% | · | |
| ROIC | -119.4% | -52.6% | · |
Liquidez y Solvencia 4
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 5.6 | 6.2 | · | |
| Quick Ratio | 5.5 | 6.1 | · | |
| Debt / Equity | 0.3 | · | · | |
| LT Debt / Equity | 0.3 | · | · |
Eficiencia 1
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · |
Tasas de Crecimiento 1
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | 100.0% | -90.0% | · |
Valoración (TTM) 14
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $10M | $5M | · | |
| Net Income TTM | $-378M | $-157M | · | |
| Market Cap | $1.98B | $342M | · | |
| Enterprise Value | $1.71B | · | · | |
| P/E | -4.3 | -0.7 | · | |
| P/S | 197.8 | 68.5 | · | |
| P/B | 8.2 | 1.1 | · | |
| P / Tangible Book | 8.2 | 1.1 | · | |
| P / Cash Flow | -11.5 | -2.9 | · | |
| P / FCF | -11.5 | -2.9 | · | |
| EV / EBITDA | -4.5 | · | · | |
| EV / FCF | -9.9 | · | · | |
| EV / Revenue | 171.4 | · | · | |
| Earnings Yield | -23.2% | -145.2% | · |
Estado de resultados 15
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1M | · | $0 | $0 | $0 | $10M | $5M | $0 | $0 | · | $0 | |
| R&D Expense | $63M | $60M | $56M | $34M | $43M | $35M | $49M | $34M | $34M | $23M | $20M | |
| SG&A Expense | $16M | $17M | $16M | $13M | $12M | $12M | $11M | $7M | $6M | $5M | $4M | |
| Operating Expenses | $109M | $77M | $238M | $53M | $55M | $47M | $61M | $41M | $40M | $28M | $25M | |
| Operating Income | $-108M | $-77M | $-238M | $-53M | $-55M | $-37M | $-56M | $-41M | $-40M | $-28M | $-25M | |
| Interest Income | $7M | $3M | · | · | $3M | $3M | · | · | · | · | · | |
| Other Non-op | $16.0K | $-24.0K | $-7M | $1M | $217.0K | $158.0K | $-5M | $2M | $2M | $472.0K | $793.0K | |
| Pretax Income | $-111M | $-81M | $-240M | $-51M | $-52M | $-34M | $-52M | $-39M | $-38M | $-28M | · | |
| Income Tax | $114.0K | · | $106.0K | $0 | $20.0K | $-205.0K | · | · | · | · | · | |
| Net Income | $-111M | $-81M | $-240M | $-51M | $-52M | $-34M | $-53M | $-39M | $-38M | $-28M | $-25M | |
| EPS (Basic) | $-1.77 | $-1.46 | $-5.17 | $-1.22 | $-1.25 | $-0.80 | $35.25 | $-5.02 | $-24.23 | $-17.89 | $-16.04 | |
| EPS (Diluted) | $-1.77 | $-1.46 | $-5.17 | $-1.22 | $-1.25 | $-0.80 | $35.25 | $-5.02 | $-24.23 | $-17.89 | $-16.04 | |
| Shares (Basic) | 63,112,314 | 55,624,631 | -81,095,490 | 42,159,340 | 41,865,400 | 41,800,802 | 2,379,909 | 7,697,695 | 1,567,269 | 1,554,087 | 3,448 | |
| Shares (Diluted) | 63,112,314 | 55,624,631 | -81,095,490 | 42,159,340 | 41,865,400 | 41,800,802 | 2,379,909 | 7,697,695 | 1,567,269 | 1,554,087 | 3,448 | |
| EBITDA | $-108M | $-77M | · | $-53M | $-55M | $-37M | · | $-41M | · | · | · |
Balance general 20
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $197M | $500M | $111M | $116M | $44M | $197M | $320M | $360M | · | · | $57M | |
| Short-term Investments | $447M | $217M | $233M | $175M | $229M | $116M | $31M | $27M | · | · | · | |
| Prepaid Expense | $11M | $13M | $8M | $6M | $5M | $5M | $5M | $7M | · | · | $3M | |
| Current Assets | $654M | $730M | $351M | $297M | $279M | $318M | $356M | $394M | · | · | $60M | |
| PP&E (Net) | $23.0K | $28.0K | $34.0K | $50.0K | $61.0K | $72.0K | $185.0K | $146.0K | · | · | $193.0K | |
| Other Non-current Assets | $16M | $15M | $14M | $14M | $12M | $13M | $13M | $9M | · | · | $7M | |
| Total Assets | $702M | $748M | $384M | $322M | $293M | $334M | $370M | $403M | · | · | $68M | |
| Accounts Payable | $8M | $9M | $7M | $6M | $8M | $20M | $17M | $15M | · | · | $5M | |
| Accrued Liabilities | $57M | $51M | $54M | $45M | $45M | $28M | $39M | $29M | · | · | $17M | |
| Current Liabilities | $66M | $61M | $63M | $52M | $53M | $49M | $57M | $44M | · | · | $23M | |
| Capital Leases | $22.0K | $77.0K | $211.0K | $180.0K | $215.0K | $317.0K | $218.0K | · | · | · | $257.0K | |
| Total Liabilities | $455M | $412M | $141M | $126M | $53M | $49M | $58M | $44M | · | · | $44M | |
| Total Debt | · | · | · | $73M | · | · | · | · | · | · | · | |
| Common Stock | $6.0K | $6.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | · | · | · | |
| Paid-in Capital | $1.21B | $1.18B | $1.01B | $721M | $713M | $705M | $700M | $694M | · | · | $5M | |
| Retained Earnings | $-958M | $-846M | $-765M | $-525M | $-473M | $-421M | $-387M | $-335M | · | · | $-230M | |
| AOCI | $-1M | $-377.0K | $-64.0K | $-69.0K | $-94.0K | $141.0K | $194.0K | $54.0K | · | · | $37.0K | |
| Stockholders' Equity | $247M | $336M | $242M | $196M | $240M | $284M | $312M | $359M | · | · | $-226M | |
| Liabilities + Equity | $702M | $748M | $384M | $322M | $293M | $334M | $370M | $403M | · | · | $68M | |
| Shares Outstanding | 63,330,747 | 62,383,377 | 54,485,518 | 42,213,465 | 42,088,697 | 41,821,887 | 41,793,412 | 41,780,938 | · | · | 1,576,854 |
Flujo de Efectivo 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $9M | $9M | $8M | $7M | $6M | $5M | $5M | $3M | $2M | $947.0K | $1M | |
| Operating Cash Flow | $-57M | $-75M | $-52M | $-41M | $-42M | $-37M | $-39M | $-31M | $-31M | $-19M | $-15M | |
| CapEx | $0 | $2.0K | $0 | $0 | $0 | $18.0K | $74.0K | $0 | $35.0K | $22.0K | · | |
| Investing Cash Flow | $-288M | $32M | $-93M | $40M | $-112M | $-86M | $-4M | $-27M | $-35.0K | $-22.0K | · | |
| Financing Cash Flow | $42M | $433M | $141M | $73M | $2M | $99.0K | $2M | $234M | $178M | $-614.0K | $50.0K | |
| Net Change in Cash | $-304M | $390M | $-5M | $72M | $-153M | $-123M | $-40M | $176M | $147M | $-20M | $-15M | |
| Free Cash Flow | · | $-75M | · | · | · | $-37M | · | · | · | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -10765.9% | · | · | · | · | -373.3% | · | · | · | · | · | |
| Net Margin | -11145.6% | · | · | · | · | -335.7% | · | · | · | · | · | |
| Pretax Margin | -11134.2% | · | · | · | · | -337.8% | · | · | · | · | · | |
| EBITDA Margin | -10765.9% | · | · | · | · | -373.3% | · | · | · | · | · | |
| ROA | -22.4% | -15.0% | · | -14.2% | -35.6% | -20.1% | · | -19.1% | · | · | · | |
| ROE | -45.8% | -26.1% | · | -18.5% | -43.6% | -23.6% | · | -21.5% | · | · | · | |
| ROIC | -43.6% | · | · | · | -23.0% | -13.1% | · | · | · | · | · |
Liquidez y Solvencia 4
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.9 | 11.9 | · | 5.7 | 5.2 | 6.5 | · | 9.0 | · | · | · | |
| Quick Ratio | 9.8 | 11.7 | · | 5.5 | 5.1 | 6.4 | · | 8.8 | · | · | · | |
| Debt / Equity | · | · | · | 0.4 | · | · | · | · | · | · | · | |
| LT Debt / Equity | · | · | · | 0.4 | · | · | · | · | · | · | · |
Eficiencia 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | 0.0 | 0.0 | 0.1 | · | · | · | · | · |
Valoración (TTM) 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | $10M | · | $10M | $10M | · | · | · | · | · | · | |
| Net Income TTM | $-296M | $-218M | · | $-176M | $-162M | $-138M | · | $-69M | · | · | · | |
| Market Cap | $1.61B | $1.22B | · | $937M | $408M | $330M | · | $707M | · | · | · | |
| Enterprise Value | · | · | · | $719M | · | · | · | · | · | · | · | |
| P/E | -4.5 | -4.1 | · | -2.7 | -0.3 | -0.2 | · | -0.4 | · | · | · | |
| P/S | · | 122.0 | · | 93.7 | 40.8 | · | · | · | · | · | · | |
| P/B | 6.5 | 3.6 | · | 4.8 | 1.7 | 1.2 | · | 2.0 | · | · | · | |
| P / Tangible Book | 6.5 | 3.6 | · | 4.8 | 1.7 | 1.2 | · | 2.0 | · | · | · | |
| P / Cash Flow | · | -16.2 | · | · | · | -8.9 | · | · | · | · | · | |
| P / FCF | · | -16.2 | · | · | · | -8.9 | · | · | · | · | · | |
| EV / EBITDA | · | · | · | -13.7 | · | · | · | · | · | · | · | |
| EV / Revenue | · | · | · | 71.9 | · | · | · | · | · | · | · | |
| Earnings Yield | -22.5% | -24.2% | · | -37.3% | -323.0% | -606.8% | · | -267.0% | · | · | · |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Ingresos | $10M | $5M | $50M |
| Margen Operativo % | -3830.6% | -3277.8% | — |
| Beneficio neto | $-378M | $-157M | $-37M |
| EPS Diluido | $-8.44 | $-11.89 | $-24.25 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Deuda / Patrimonio | 0.3 | — | — |
| Ratio corriente | 5.6 | 6.2 | — |
| Ratio Rápido | 5.5 | 6.1 | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Flujo de caja libre | $-172M | $-120M | — |
Últimas noticias Noticias recientes que mencionan a esta empresa
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Propietarios institucionales (13F) 152 declarantes · $1.3B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 35 (-11 vs trimestre anterior) | 21 (-13 vs trimestre anterior) | 61 (+1 vs trimestre anterior) | 36 (+19 vs trimestre anterior) | +7.0M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| FMR LLC | $189 573 930 | 7 469 422 | 14,77% | Acciones |
| SR One Capital Management, LP | $127 860 735 | 5 037 854 | 9,96% | Acciones |
| NEA Management Company, LLC | $102 109 298 | 4 023 219 | 7,95% | Acciones |
| ENAVATE SCIENCES GP, LLC | $99 468 255 | 3 919 159 | 7,75% | Acciones |
| FEDERATED HERMES, INC. | $79 104 511 | 3 116 805 | 6,16% | Acciones |
| Capital International Investors | $63 523 907 | 2 502 912 | 4,95% | Acciones |
| Polar Capital Holdings Plc | $61 236 153 | 2 412 772 | 4,77% | Acciones |
| Fairmount Funds Management LLC | $59 872 055 | 2 359 025 | 4,66% | Acciones |
| STATE STREET CORP | $52 158 438 | 2 055 100 | 4,06% | Acciones |
| NVP ASSOCIATES, LLC | $46 660 673 | 1 838 482 | 3,63% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $34 386 448 | 1 354 864 | 2,68% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $32 046 159 | 1 262 654 | 2,50% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $21 571 235 | 1 103 388 | 1,68% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $20 688 507 | 815 150 | 1,61% | Acciones |
| EcoR1 Capital, LLC | $20 037 510 | 789 500 | 1,56% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $19 157 734 | 754 651 | 1,49% | Acciones |
| BANK OF AMERICA CORP /DE/ | $17 914 016 | 705 832 | 1,40% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $16 762 729 | 660 470 | 1,31% | Acciones |
| Woodline Partners LP | $14 987 880 | 590 539 | 1,17% | Acciones |
| Balyasny Asset Management L.P. | $14 637 077 | 576 717 | 1,14% | Acciones |
| ArrowMark Colorado Holdings LLC | $14 550 811 | 573 318 | 1,13% | Acciones |
| SILVERARC CAPITAL MANAGEMENT, LLC | $12 938 445 | 509 789 | 1,01% | Acciones |
| Rock Springs Capital Management LP | $12 742 714 | 502 077 | 0,99% | Acciones |
| Pivotal bioVenture Partners Investment Advisor LLC | $12 455 641 | 490 766 | 0,97% | Acciones |
| NEXTBio Capital Management LP | $10 830 560 | 426 736 | 0,84% | Acciones |
| Vestal Point Capital, LP | $9 263 700 | 365 000 | 0,72% | Acciones |
| JENNISON ASSOCIATES LLC | $7 970 564 | 314 049 | 0,62% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $7 737 601 | 304 870 | 0,60% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7 666 917 | 302 085 | 0,60% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $6 462 332 | 254 623 | 0,50% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $5 858 567 | 230 834 | 0,46% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5 740 956 | 226 200 | 0,45% | Opción de compra |
| Walleye Capital LLC | $5 305 689 | 209 050 | 0,41% | Acciones |
| Sio Capital Management, LLC | $5 293 177 | 208 557 | 0,41% | Acciones |
| Voleon Capital Management LP | $4 242 140 | 167 145 | 0,33% | Acciones |
| CITADEL ADVISORS LLC | $4 231 024 | 166 707 | 0,33% | Acciones |
| UBS Group AG | $4 150 239 | 163 524 | 0,32% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $3 834 563 | 151 086 | 0,30% | Acciones |
| GOLDMAN SACHS GROUP INC | $3 814 842 | 150 309 | 0,30% | Acciones |
| Squarepoint Ops LLC | $3 177 195 | 125 185 | 0,25% | Acciones |
| BARCLAYS PLC | $2 858 652 | 112 634 | 0,22% | Acciones |
| SEVEN GRAND MANAGERS, LLC | $2 538 000 | 100 000 | 0,20% | Acciones |
| Birchview Capital, LP | $2 375 593 | 93 601 | 0,19% | Acciones |
| Verition Fund Management LLC | $1 852 435 | 72 988 | 0,14% | Acciones |
| J. Goldman & Co LP | $1 731 728 | 68 232 | 0,13% | Acciones |
| ALPS ADVISORS INC | $1 616 072 | 63 675 | 0,13% | Acciones |
| Swiss National Bank | $1 350 216 | 53 200 | 0,11% | Acciones |
| Exome Asset Management LLC | $1 331 003 | 52 443 | 0,10% | Acciones |
| Jump Financial, LLC | $1 294 939 | 51 022 | 0,10% | Acciones |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1 230 042 | 48 465 | 0,10% | Acciones |
| CITIGROUP INC | $1 215 118 | 47 877 | 0,09% | Acciones |
| XTX Topco Ltd | $1 016 063 | 40 034 | 0,08% | Acciones |
| Burkehill Global Management, LP | $1 015 200 | 40 000 | 0,08% | Acciones |
| JANE STREET GROUP, LLC | $989 820 | 39 000 | 0,08% | Opción de compra |
| Rafferty Asset Management, LLC | $951 978 | 37 509 | 0,07% | Acciones |
| Atom Investors LP | $942 842 | 37 149 | 0,07% | Acciones |
| RHUMBLINE ADVISERS | $869 128 | 34 245 | 0,07% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $844 646 | 33 280 | 0,07% | Acciones |
| CITADEL ADVISORS LLC | $784 242 | 30 900 | 0,06% | Opción de compra |
| DCF Advisers, LLC | $715 310 | 28 184 | 0,06% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $683 280 | 26 922 | 0,05% | Acciones |
| WELLS FARGO & COMPANY/MN | $659 753 | 25 995 | 0,05% | Acciones |
| MARSHALL WACE, LLP | $597 978 | 23 561 | 0,05% | Acciones |
| BlackRock, Inc. | $580 364 | 22 867 | 0,05% | Acciones |
| VANGUARD GROUP INC | $535 500 | 14 748 | 0,04% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $523 412 | 20 623 | 0,04% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $479 682 | 18 900 | 0,04% | Opción de venta |
| China Universal Asset Management Co., Ltd. | $478 362 | 18 848 | 0,04% | Acciones |
| PROFUND ADVISORS LLC | $478 108 | 18 838 | 0,04% | Acciones |
| ALLSTATE CORP | $462 957 | 18 241 | 0,04% | Acciones |
| Y-Intercept (Hong Kong) Ltd | $439 886 | 17 332 | 0,03% | Acciones |
| MetLife Investment Management, LLC | $432 501 | 17 041 | 0,03% | Acciones |
| Virtus Investment Advisers, LLC | $419 405 | 16 525 | 0,03% | Acciones |
| Bank of New York Mellon Corp | $418 592 | 16 493 | 0,03% | Acciones |
| Point72 Asset Management, L.P. | $409 532 | 16 136 | 0,03% | Acciones |
| Vanguard Global Advisers, LLC | $389 126 | 15 332 | 0,03% | Acciones |
| NORDEA INVESTMENT MANAGEMENT AB | $382 872 | 15 050 | 0,03% | Acciones |
| Brevan Howard Capital Management LP | $372 426 | 14 674 | 0,03% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $331 615 | 13 066 | 0,03% | Acciones |
| Engineers Gate Manager LP | $329 432 | 12 980 | 0,03% | Acciones |
| Russell Investments Group, Ltd. | $323 341 | 12 740 | 0,03% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $309 261 | 15 819 | 0,02% | Acciones |
| Invesco Ltd. | $286 337 | 11 282 | 0,02% | Acciones |
| VARCOV Co. | $266 617 | 10 505 | 0,02% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $261 414 | 10 300 | 0,02% | Acciones |
| JPMORGAN CHASE & CO | $245 152 | 8 188 | 0,02% | Acciones |
| Scientech Research LLC | $229 131 | 9 028 | 0,02% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $225 222 | 8 874 | 0,02% | Acciones |
| Quantinno Capital Management LP | $217 786 | 8 581 | 0,02% | Acciones |
| State of New Jersey Common Pension Fund D | $217 532 | 8 571 | 0,02% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $213 649 | 8 418 | 0,02% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $203 852 | 8 032 | 0,02% | Acciones |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $191 949 | 7 563 | 0,01% | Acciones |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $191 086 | 7 529 | 0,01% | Acciones |
| Nuveen Asset Management, LLC | $163 055 | 19 909 | 0,01% | Acciones |
| KLP KAPITALFORVALTNING AS | $154 818 | 6 100 | 0,01% | Acciones |
| PNC Financial Services Group, Inc. | $114 845 | 4 525 | 0,01% | Acciones |
| NORTHERN TRUST CORP | $113 601 | 4 476 | 0,01% | Acciones |
| Vanguard Investments Australia, Ltd. | $106 571 | 4 199 | 0,01% | Acciones |
| Mirae Asset Global Investments Co., Ltd. | $71 673 | 2 824 | 0,01% | Acciones |
Informantes de la empresa 13 insiders · 5 directivos · 8 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| MOULDER LEON O JR | Chief Executive Officer | 15 de junio de 2026 A | 96 928 | 10 | 0 | $6 533 809 |
| Jennifer A. Fox | Chief Business Officer and Chief Financial Officer | 15 de junio de 2026 A | 1 592 | 0 | 0 | $0 |
| Joseph L Farmer | President and Chief Operating Officer | 15 de junio de 2026 A | 974 | 0 | 0 | $0 |
| Lisa Von Moltke | Head of Research and Development and Chief Medical Officer | 15 de junio de 2026 A | — | 0 | 0 | $0 |
| Orlando Oliveira | Chief Commercial Officer | 10 de junio de 2025 A | — | 0 | 0 | $0 |
| James P Boylan | Consejero | 15 de junio de 2026 A | — | 0 | 0 | $0 |
| Hongbo Lu | Consejero | 15 de junio de 2026 A | 426 736 | 5 | 0 | $8 154 891 |
| John J Orloff | Consejero | 15 de junio de 2026 A | — | 0 | 0 | $0 |
| Jason Raleigh Nunn | Consejero | 15 de junio de 2026 A | 1 173 395 | 1 | 0 | $1 200 002 |
| Patricia L Allen | Consejero | 15 de junio de 2026 A | 19 860 | 4 | 0 | $499 746 |
| Patrick G. Enright | Consejero | 15 de junio de 2026 A | 11 990 | 2 | 0 | $2 250 027 |
| Ting Xiao | Consejero | 7 de febrero de 2025 P | 10 000 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | Propietario del 10% | 16 de septiembre de 2024 C | 801 624 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 4 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| SR One Capital Management, LLC, SR One Capital Fund II Aggregator, LP, SR One Capital Partners II, LP, AMZL, LP, SR One Capital SMA Partners, LP, SR One Capital Opportunities Fund I, LP, SR One Capital Opportunities Partners I, LP, Simeon George ×3 presentaciones | 17 de agosto de 2026 | 7,70% | Enmienda | — | SEC |
| MOULDER LEON O JR, Tellus BioVentures, LLC, Leon O. Moulder, Jr. Revocable Trust U/A dtd 9/9/2008 ×5 presentaciones | 5 de mayo de 2026 | 5,09% | Presentación inicial | Inversión pasiva | SEC |
| Enavate Sciences GP, LLC, Zebra Aggregator, LP ×2 presentaciones | 14 de octubre de 2025 | 7,30% | Enmienda | — | SEC |
| Longitude Capital Partners IV, LLC, Longitude Venture Partners IV, L.P., Longitude Prime Partners, LLC, Longitude Prime Fund, L.P., Patrick G. Enright, Juliet Tammenoms Bakker ×2 presentaciones | 14 de octubre de 2025 | 4,90% | Enmienda | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 36 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 0,63% | 55 332 NS | 31 de mayo de 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,44% | 9 817 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,35% | 6 799 NS | 30 de abril de 2026 | N-PORT |
| IWC · iShares Trust | 0,21% | 96 703 SH | 8 de agosto de 2026 | Diario |
| LABU · Direxion Shares ETF Trust | 0,19% | 51 847 NS | 30 de abril de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,14% | 3 433 SH | 8 de agosto de 2026 | Diario |
| FFSM · FIDELITY COVINGTON TRUST | 0,09% | 56 997 NS | 30 de abril de 2026 | N-PORT |
| IBB · iShares Trust | 0,08% | 235 244 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,06% | 261 112 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,05% | 1 983 NS | 31 de mayo de 2026 | N-PORT |
| PKW · Invesco Exchange-Traded Fund Trust | 0,05% | 24 662 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,04% | 27 907 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,04% | 30 536 SH | 8 de agosto de 2026 | Diario |
| ISCV · iShares Trust | 0,03% | 6 636 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,03% | 729 732 SH | 8 de agosto de 2026 | Diario |
| GSSC · Goldman Sachs ETF Trust | 0,03% | 15 596 NS | 31 de mayo de 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,03% | 9 928 NS | 30 de abril de 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 164 002 SH | 8 de agosto de 2026 | Diario |
| ISCB · iShares Trust | 0,02% | 1 340 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,01% | 10 171 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 1 108 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 134 982 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 435 390 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 79 801 SH | 8 de agosto de 2026 | Diario |
| WSML · iShares Trust | 0,01% | 1 963 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,01% | 865 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 7 339 NS | 30 de abril de 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 874 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 16 937 NS | 31 de mayo de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 58 988 SH | 8 de agosto de 2026 | Diario |
| HDG · ProShares Trust | 0,00% | 22 NS | 31 de mayo de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 595 NS | 31 de mayo de 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 4 711 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 16 334 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 891 196 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 2 624 SH | 8 de agosto de 2026 | Diario |