ACET — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $8 057 871 | 932 624 | 14,03% | Actions |
| ORBIMED ADVISORS LLC | $7 298 960 | 844 787 | 12,71% | Actions |
| FRANKLIN RESOURCES INC | $5 413 573 | 626 571 | 9,43% | Actions |
| CITADEL ADVISORS LLC | $3 738 856 | 432 738 | 6,51% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $2 965 490 | 343 228 | 5,17% | Actions |
| VANGUARD GROUP INC | $2 452 552 | 291 277 | 4,27% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $2 370 600 | 274 375 | 4,13% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $2 297 765 | 265 945 | 4,00% | Actions |
| Stonepine Capital Management, LLC | $2 121 276 | 245 518 | 3,69% | Actions |
| Aquilo Capital Management, LLC | $1 854 426 | 2 456 194 | 3,23% | Actions |
| Alyeska Investment Group, L.P. | $1 760 823 | 203 799 | 3,07% | Actions |
| Schonfeld Strategic Advisors LLC | $1 689 238 | 195 514 | 2,94% | Actions |
| Carlyle Group Inc. | $1 592 308 | 184 295 | 2,77% | Actions |
| NEXTBio Capital Management LP | $1 363 625 | 157 827 | 2,38% | Actions |
| TWO SIGMA ADVISERS, LP | $937 449 | 111 336 | 1,63% | Actions |
| TWO SIGMA INVESTMENTS, LP | $836 689 | 96 839 | 1,46% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $826 703 | 95 634 | 1,44% | Actions |
| DAFNA Capital Management LLC | $810 536 | 93 812 | 1,41% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $742 686 | 85 959 | 1,29% | Actions |
| MARSHALL WACE, LLP | $686 775 | 79 488 | 1,20% | Actions |
| Trexquant Investment LP | $673 937 | 78 002 | 1,17% | Actions |
| JANE STREET GROUP, LLC | $609 647 | 70 561 | 1,06% | Actions |
| Burkehill Global Management, LP | $540 000 | 62 500 | 0,94% | Actions |
| BlackRock, Inc. | $536 769 | 62 126 | 0,93% | Actions |
| REGENERON PHARMACEUTICALS, INC. | $522 819 | 60 511 | 0,91% | Actions |
| Rangeley Capital, LLC | $439 707 | 50 892 | 0,77% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $437 789 | 50 670 | 0,76% | Actions |
| RBF Capital, LLC | $333 348 | 38 582 | 0,58% | Actions |
| STATE STREET CORP | $312 958 | 36 222 | 0,55% | Actions |
| Quadrature Capital Ltd | $312 708 | 36 193 | 0,54% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $273 049 | 31 603 | 0,48% | Actions |
| UBS Group AG | $257 619 | 29 817 | 0,45% | Actions |
| Verdad Advisers, LP | $217 728 | 25 200 | 0,38% | Actions |
| XTX Topco Ltd | $209 814 | 24 284 | 0,37% | Actions |
| CITADEL ADVISORS LLC | $196 992 | 22 800 | 0,34% | Option de vente |
| JOHNSON & JOHNSON | $196 811 | 22 779 | 0,34% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $178 416 | 20 650 | 0,31% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $169 344 | 19 600 | 0,29% | Option de vente |
| PRELUDE CAPITAL MANAGEMENT, LLC | $160 272 | 18 550 | 0,28% | Actions |
| NORTHERN TRUST CORP | $159 287 | 18 436 | 0,28% | Actions |
| OCCUDO QUANTITATIVE STRATEGIES LP | $143 735 | 16 636 | 0,25% | Actions |
| Squarepoint Ops LLC | $131 795 | 15 254 | 0,23% | Actions |
| Vontobel Holding Ltd. | $119 025 | 13 776 | 0,21% | Actions |
| AXQ CAPITAL, LP | $94 962 | 10 991 | 0,17% | Actions |
| Jump Financial, LLC | $94 539 | 10 942 | 0,16% | Actions |
| CITADEL ADVISORS LLC | $92 534 | 10 710 | 0,16% | Option d'achat |
| Arax Advisory Partners | $51 840 | 6 000 | 0,09% | Actions |
| Vanguard Global Advisers, LLC | $45 109 | 5 221 | 0,08% | Actions |
| SIMPLEX TRADING, LLC | $41 592 | 4 814 | 0,07% | Actions |
| MORGAN STANLEY | $19 795 | 2 291 | 0,03% | Actions |
| ROYAL BANK OF CANADA | $15 000 | 1 701 | 0,03% | Actions |
| Tower Research Capital LLC (TRC) | $2 393 | 277 | 0,00% | Actions |
| JPMORGAN CHASE & CO | $1 677 | 196 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $1 076 | 124 832 | 0,00% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $432 | 50 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $406 | 47 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $207 | 24 | 0,00% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $146 | 17 | 0,00% | Actions |
| FMR LLC | $52 | 6 | 0,00% | Actions |
| TD Waterhouse Canada Inc. | $26 | 3 | 0,00% | Actions |
| DANSKE BANK A/S | $9 | 1 | 0,00% | Actions |
| Avion Wealth | $2 | 246 | 0,00% | Actions |